Annotation of imach/src/imach.c, revision 1.259

1.259   ! brouard     1: /* $Id: imach.c,v 1.258 2017/04/03 10:17:47 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.259   ! brouard     4:   Revision 1.258  2017/04/03 10:17:47  brouard
        !             5:   Summary: Version 0.99r12
        !             6: 
        !             7:   Some cleanings, conformed with updated documentation.
        !             8: 
1.258     brouard     9:   Revision 1.257  2017/03/29 16:53:30  brouard
                     10:   Summary: Temp
                     11: 
1.257     brouard    12:   Revision 1.256  2017/03/27 05:50:23  brouard
                     13:   Summary: Temporary
                     14: 
1.256     brouard    15:   Revision 1.255  2017/03/08 16:02:28  brouard
                     16:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     17: 
1.255     brouard    18:   Revision 1.254  2017/03/08 07:13:00  brouard
                     19:   Summary: Fixing data parameter line
                     20: 
1.254     brouard    21:   Revision 1.253  2016/12/15 11:59:41  brouard
                     22:   Summary: 0.99 in progress
                     23: 
1.253     brouard    24:   Revision 1.252  2016/09/15 21:15:37  brouard
                     25:   *** empty log message ***
                     26: 
1.252     brouard    27:   Revision 1.251  2016/09/15 15:01:13  brouard
                     28:   Summary: not working
                     29: 
1.251     brouard    30:   Revision 1.250  2016/09/08 16:07:27  brouard
                     31:   Summary: continue
                     32: 
1.250     brouard    33:   Revision 1.249  2016/09/07 17:14:18  brouard
                     34:   Summary: Starting values from frequencies
                     35: 
1.249     brouard    36:   Revision 1.248  2016/09/07 14:10:18  brouard
                     37:   *** empty log message ***
                     38: 
1.248     brouard    39:   Revision 1.247  2016/09/02 11:11:21  brouard
                     40:   *** empty log message ***
                     41: 
1.247     brouard    42:   Revision 1.246  2016/09/02 08:49:22  brouard
                     43:   *** empty log message ***
                     44: 
1.246     brouard    45:   Revision 1.245  2016/09/02 07:25:01  brouard
                     46:   *** empty log message ***
                     47: 
1.245     brouard    48:   Revision 1.244  2016/09/02 07:17:34  brouard
                     49:   *** empty log message ***
                     50: 
1.244     brouard    51:   Revision 1.243  2016/09/02 06:45:35  brouard
                     52:   *** empty log message ***
                     53: 
1.243     brouard    54:   Revision 1.242  2016/08/30 15:01:20  brouard
                     55:   Summary: Fixing a lots
                     56: 
1.242     brouard    57:   Revision 1.241  2016/08/29 17:17:25  brouard
                     58:   Summary: gnuplot problem in Back projection to fix
                     59: 
1.241     brouard    60:   Revision 1.240  2016/08/29 07:53:18  brouard
                     61:   Summary: Better
                     62: 
1.240     brouard    63:   Revision 1.239  2016/08/26 15:51:03  brouard
                     64:   Summary: Improvement in Powell output in order to copy and paste
                     65: 
                     66:   Author:
                     67: 
1.239     brouard    68:   Revision 1.238  2016/08/26 14:23:35  brouard
                     69:   Summary: Starting tests of 0.99
                     70: 
1.238     brouard    71:   Revision 1.237  2016/08/26 09:20:19  brouard
                     72:   Summary: to valgrind
                     73: 
1.237     brouard    74:   Revision 1.236  2016/08/25 10:50:18  brouard
                     75:   *** empty log message ***
                     76: 
1.236     brouard    77:   Revision 1.235  2016/08/25 06:59:23  brouard
                     78:   *** empty log message ***
                     79: 
1.235     brouard    80:   Revision 1.234  2016/08/23 16:51:20  brouard
                     81:   *** empty log message ***
                     82: 
1.234     brouard    83:   Revision 1.233  2016/08/23 07:40:50  brouard
                     84:   Summary: not working
                     85: 
1.233     brouard    86:   Revision 1.232  2016/08/22 14:20:21  brouard
                     87:   Summary: not working
                     88: 
1.232     brouard    89:   Revision 1.231  2016/08/22 07:17:15  brouard
                     90:   Summary: not working
                     91: 
1.231     brouard    92:   Revision 1.230  2016/08/22 06:55:53  brouard
                     93:   Summary: Not working
                     94: 
1.230     brouard    95:   Revision 1.229  2016/07/23 09:45:53  brouard
                     96:   Summary: Completing for func too
                     97: 
1.229     brouard    98:   Revision 1.228  2016/07/22 17:45:30  brouard
                     99:   Summary: Fixing some arrays, still debugging
                    100: 
1.227     brouard   101:   Revision 1.226  2016/07/12 18:42:34  brouard
                    102:   Summary: temp
                    103: 
1.226     brouard   104:   Revision 1.225  2016/07/12 08:40:03  brouard
                    105:   Summary: saving but not running
                    106: 
1.225     brouard   107:   Revision 1.224  2016/07/01 13:16:01  brouard
                    108:   Summary: Fixes
                    109: 
1.224     brouard   110:   Revision 1.223  2016/02/19 09:23:35  brouard
                    111:   Summary: temporary
                    112: 
1.223     brouard   113:   Revision 1.222  2016/02/17 08:14:50  brouard
                    114:   Summary: Probably last 0.98 stable version 0.98r6
                    115: 
1.222     brouard   116:   Revision 1.221  2016/02/15 23:35:36  brouard
                    117:   Summary: minor bug
                    118: 
1.220     brouard   119:   Revision 1.219  2016/02/15 00:48:12  brouard
                    120:   *** empty log message ***
                    121: 
1.219     brouard   122:   Revision 1.218  2016/02/12 11:29:23  brouard
                    123:   Summary: 0.99 Back projections
                    124: 
1.218     brouard   125:   Revision 1.217  2015/12/23 17:18:31  brouard
                    126:   Summary: Experimental backcast
                    127: 
1.217     brouard   128:   Revision 1.216  2015/12/18 17:32:11  brouard
                    129:   Summary: 0.98r4 Warning and status=-2
                    130: 
                    131:   Version 0.98r4 is now:
                    132:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    133:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    134:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    135: 
1.216     brouard   136:   Revision 1.215  2015/12/16 08:52:24  brouard
                    137:   Summary: 0.98r4 working
                    138: 
1.215     brouard   139:   Revision 1.214  2015/12/16 06:57:54  brouard
                    140:   Summary: temporary not working
                    141: 
1.214     brouard   142:   Revision 1.213  2015/12/11 18:22:17  brouard
                    143:   Summary: 0.98r4
                    144: 
1.213     brouard   145:   Revision 1.212  2015/11/21 12:47:24  brouard
                    146:   Summary: minor typo
                    147: 
1.212     brouard   148:   Revision 1.211  2015/11/21 12:41:11  brouard
                    149:   Summary: 0.98r3 with some graph of projected cross-sectional
                    150: 
                    151:   Author: Nicolas Brouard
                    152: 
1.211     brouard   153:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   154:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   155:   Summary: Adding ftolpl parameter
                    156:   Author: N Brouard
                    157: 
                    158:   We had difficulties to get smoothed confidence intervals. It was due
                    159:   to the period prevalence which wasn't computed accurately. The inner
                    160:   parameter ftolpl is now an outer parameter of the .imach parameter
                    161:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    162:   computation are long.
                    163: 
1.209     brouard   164:   Revision 1.208  2015/11/17 14:31:57  brouard
                    165:   Summary: temporary
                    166: 
1.208     brouard   167:   Revision 1.207  2015/10/27 17:36:57  brouard
                    168:   *** empty log message ***
                    169: 
1.207     brouard   170:   Revision 1.206  2015/10/24 07:14:11  brouard
                    171:   *** empty log message ***
                    172: 
1.206     brouard   173:   Revision 1.205  2015/10/23 15:50:53  brouard
                    174:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    175: 
1.205     brouard   176:   Revision 1.204  2015/10/01 16:20:26  brouard
                    177:   Summary: Some new graphs of contribution to likelihood
                    178: 
1.204     brouard   179:   Revision 1.203  2015/09/30 17:45:14  brouard
                    180:   Summary: looking at better estimation of the hessian
                    181: 
                    182:   Also a better criteria for convergence to the period prevalence And
                    183:   therefore adding the number of years needed to converge. (The
                    184:   prevalence in any alive state shold sum to one
                    185: 
1.203     brouard   186:   Revision 1.202  2015/09/22 19:45:16  brouard
                    187:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    188: 
1.202     brouard   189:   Revision 1.201  2015/09/15 17:34:58  brouard
                    190:   Summary: 0.98r0
                    191: 
                    192:   - Some new graphs like suvival functions
                    193:   - Some bugs fixed like model=1+age+V2.
                    194: 
1.201     brouard   195:   Revision 1.200  2015/09/09 16:53:55  brouard
                    196:   Summary: Big bug thanks to Flavia
                    197: 
                    198:   Even model=1+age+V2. did not work anymore
                    199: 
1.200     brouard   200:   Revision 1.199  2015/09/07 14:09:23  brouard
                    201:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    202: 
1.199     brouard   203:   Revision 1.198  2015/09/03 07:14:39  brouard
                    204:   Summary: 0.98q5 Flavia
                    205: 
1.198     brouard   206:   Revision 1.197  2015/09/01 18:24:39  brouard
                    207:   *** empty log message ***
                    208: 
1.197     brouard   209:   Revision 1.196  2015/08/18 23:17:52  brouard
                    210:   Summary: 0.98q5
                    211: 
1.196     brouard   212:   Revision 1.195  2015/08/18 16:28:39  brouard
                    213:   Summary: Adding a hack for testing purpose
                    214: 
                    215:   After reading the title, ftol and model lines, if the comment line has
                    216:   a q, starting with #q, the answer at the end of the run is quit. It
                    217:   permits to run test files in batch with ctest. The former workaround was
                    218:   $ echo q | imach foo.imach
                    219: 
1.195     brouard   220:   Revision 1.194  2015/08/18 13:32:00  brouard
                    221:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    222: 
1.194     brouard   223:   Revision 1.193  2015/08/04 07:17:42  brouard
                    224:   Summary: 0.98q4
                    225: 
1.193     brouard   226:   Revision 1.192  2015/07/16 16:49:02  brouard
                    227:   Summary: Fixing some outputs
                    228: 
1.192     brouard   229:   Revision 1.191  2015/07/14 10:00:33  brouard
                    230:   Summary: Some fixes
                    231: 
1.191     brouard   232:   Revision 1.190  2015/05/05 08:51:13  brouard
                    233:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    234: 
                    235:   Fix 1+age+.
                    236: 
1.190     brouard   237:   Revision 1.189  2015/04/30 14:45:16  brouard
                    238:   Summary: 0.98q2
                    239: 
1.189     brouard   240:   Revision 1.188  2015/04/30 08:27:53  brouard
                    241:   *** empty log message ***
                    242: 
1.188     brouard   243:   Revision 1.187  2015/04/29 09:11:15  brouard
                    244:   *** empty log message ***
                    245: 
1.187     brouard   246:   Revision 1.186  2015/04/23 12:01:52  brouard
                    247:   Summary: V1*age is working now, version 0.98q1
                    248: 
                    249:   Some codes had been disabled in order to simplify and Vn*age was
                    250:   working in the optimization phase, ie, giving correct MLE parameters,
                    251:   but, as usual, outputs were not correct and program core dumped.
                    252: 
1.186     brouard   253:   Revision 1.185  2015/03/11 13:26:42  brouard
                    254:   Summary: Inclusion of compile and links command line for Intel Compiler
                    255: 
1.185     brouard   256:   Revision 1.184  2015/03/11 11:52:39  brouard
                    257:   Summary: Back from Windows 8. Intel Compiler
                    258: 
1.184     brouard   259:   Revision 1.183  2015/03/10 20:34:32  brouard
                    260:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    261: 
                    262:   We use directest instead of original Powell test; probably no
                    263:   incidence on the results, but better justifications;
                    264:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    265:   wrong results.
                    266: 
1.183     brouard   267:   Revision 1.182  2015/02/12 08:19:57  brouard
                    268:   Summary: Trying to keep directest which seems simpler and more general
                    269:   Author: Nicolas Brouard
                    270: 
1.182     brouard   271:   Revision 1.181  2015/02/11 23:22:24  brouard
                    272:   Summary: Comments on Powell added
                    273: 
                    274:   Author:
                    275: 
1.181     brouard   276:   Revision 1.180  2015/02/11 17:33:45  brouard
                    277:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    278: 
1.180     brouard   279:   Revision 1.179  2015/01/04 09:57:06  brouard
                    280:   Summary: back to OS/X
                    281: 
1.179     brouard   282:   Revision 1.178  2015/01/04 09:35:48  brouard
                    283:   *** empty log message ***
                    284: 
1.178     brouard   285:   Revision 1.177  2015/01/03 18:40:56  brouard
                    286:   Summary: Still testing ilc32 on OSX
                    287: 
1.177     brouard   288:   Revision 1.176  2015/01/03 16:45:04  brouard
                    289:   *** empty log message ***
                    290: 
1.176     brouard   291:   Revision 1.175  2015/01/03 16:33:42  brouard
                    292:   *** empty log message ***
                    293: 
1.175     brouard   294:   Revision 1.174  2015/01/03 16:15:49  brouard
                    295:   Summary: Still in cross-compilation
                    296: 
1.174     brouard   297:   Revision 1.173  2015/01/03 12:06:26  brouard
                    298:   Summary: trying to detect cross-compilation
                    299: 
1.173     brouard   300:   Revision 1.172  2014/12/27 12:07:47  brouard
                    301:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    302: 
1.172     brouard   303:   Revision 1.171  2014/12/23 13:26:59  brouard
                    304:   Summary: Back from Visual C
                    305: 
                    306:   Still problem with utsname.h on Windows
                    307: 
1.171     brouard   308:   Revision 1.170  2014/12/23 11:17:12  brouard
                    309:   Summary: Cleaning some \%% back to %%
                    310: 
                    311:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    312: 
1.170     brouard   313:   Revision 1.169  2014/12/22 23:08:31  brouard
                    314:   Summary: 0.98p
                    315: 
                    316:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    317: 
1.169     brouard   318:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   319:   Summary: update
1.169     brouard   320: 
1.168     brouard   321:   Revision 1.167  2014/12/22 13:50:56  brouard
                    322:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    323: 
                    324:   Testing on Linux 64
                    325: 
1.167     brouard   326:   Revision 1.166  2014/12/22 11:40:47  brouard
                    327:   *** empty log message ***
                    328: 
1.166     brouard   329:   Revision 1.165  2014/12/16 11:20:36  brouard
                    330:   Summary: After compiling on Visual C
                    331: 
                    332:   * imach.c (Module): Merging 1.61 to 1.162
                    333: 
1.165     brouard   334:   Revision 1.164  2014/12/16 10:52:11  brouard
                    335:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    336: 
                    337:   * imach.c (Module): Merging 1.61 to 1.162
                    338: 
1.164     brouard   339:   Revision 1.163  2014/12/16 10:30:11  brouard
                    340:   * imach.c (Module): Merging 1.61 to 1.162
                    341: 
1.163     brouard   342:   Revision 1.162  2014/09/25 11:43:39  brouard
                    343:   Summary: temporary backup 0.99!
                    344: 
1.162     brouard   345:   Revision 1.1  2014/09/16 11:06:58  brouard
                    346:   Summary: With some code (wrong) for nlopt
                    347: 
                    348:   Author:
                    349: 
                    350:   Revision 1.161  2014/09/15 20:41:41  brouard
                    351:   Summary: Problem with macro SQR on Intel compiler
                    352: 
1.161     brouard   353:   Revision 1.160  2014/09/02 09:24:05  brouard
                    354:   *** empty log message ***
                    355: 
1.160     brouard   356:   Revision 1.159  2014/09/01 10:34:10  brouard
                    357:   Summary: WIN32
                    358:   Author: Brouard
                    359: 
1.159     brouard   360:   Revision 1.158  2014/08/27 17:11:51  brouard
                    361:   *** empty log message ***
                    362: 
1.158     brouard   363:   Revision 1.157  2014/08/27 16:26:55  brouard
                    364:   Summary: Preparing windows Visual studio version
                    365:   Author: Brouard
                    366: 
                    367:   In order to compile on Visual studio, time.h is now correct and time_t
                    368:   and tm struct should be used. difftime should be used but sometimes I
                    369:   just make the differences in raw time format (time(&now).
                    370:   Trying to suppress #ifdef LINUX
                    371:   Add xdg-open for __linux in order to open default browser.
                    372: 
1.157     brouard   373:   Revision 1.156  2014/08/25 20:10:10  brouard
                    374:   *** empty log message ***
                    375: 
1.156     brouard   376:   Revision 1.155  2014/08/25 18:32:34  brouard
                    377:   Summary: New compile, minor changes
                    378:   Author: Brouard
                    379: 
1.155     brouard   380:   Revision 1.154  2014/06/20 17:32:08  brouard
                    381:   Summary: Outputs now all graphs of convergence to period prevalence
                    382: 
1.154     brouard   383:   Revision 1.153  2014/06/20 16:45:46  brouard
                    384:   Summary: If 3 live state, convergence to period prevalence on same graph
                    385:   Author: Brouard
                    386: 
1.153     brouard   387:   Revision 1.152  2014/06/18 17:54:09  brouard
                    388:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    389: 
1.152     brouard   390:   Revision 1.151  2014/06/18 16:43:30  brouard
                    391:   *** empty log message ***
                    392: 
1.151     brouard   393:   Revision 1.150  2014/06/18 16:42:35  brouard
                    394:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    395:   Author: brouard
                    396: 
1.150     brouard   397:   Revision 1.149  2014/06/18 15:51:14  brouard
                    398:   Summary: Some fixes in parameter files errors
                    399:   Author: Nicolas Brouard
                    400: 
1.149     brouard   401:   Revision 1.148  2014/06/17 17:38:48  brouard
                    402:   Summary: Nothing new
                    403:   Author: Brouard
                    404: 
                    405:   Just a new packaging for OS/X version 0.98nS
                    406: 
1.148     brouard   407:   Revision 1.147  2014/06/16 10:33:11  brouard
                    408:   *** empty log message ***
                    409: 
1.147     brouard   410:   Revision 1.146  2014/06/16 10:20:28  brouard
                    411:   Summary: Merge
                    412:   Author: Brouard
                    413: 
                    414:   Merge, before building revised version.
                    415: 
1.146     brouard   416:   Revision 1.145  2014/06/10 21:23:15  brouard
                    417:   Summary: Debugging with valgrind
                    418:   Author: Nicolas Brouard
                    419: 
                    420:   Lot of changes in order to output the results with some covariates
                    421:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    422:   improve the code.
                    423:   No more memory valgrind error but a lot has to be done in order to
                    424:   continue the work of splitting the code into subroutines.
                    425:   Also, decodemodel has been improved. Tricode is still not
                    426:   optimal. nbcode should be improved. Documentation has been added in
                    427:   the source code.
                    428: 
1.144     brouard   429:   Revision 1.143  2014/01/26 09:45:38  brouard
                    430:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    431: 
                    432:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    433:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    434: 
1.143     brouard   435:   Revision 1.142  2014/01/26 03:57:36  brouard
                    436:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    437: 
                    438:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    439: 
1.142     brouard   440:   Revision 1.141  2014/01/26 02:42:01  brouard
                    441:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    442: 
1.141     brouard   443:   Revision 1.140  2011/09/02 10:37:54  brouard
                    444:   Summary: times.h is ok with mingw32 now.
                    445: 
1.140     brouard   446:   Revision 1.139  2010/06/14 07:50:17  brouard
                    447:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    448:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    449: 
1.139     brouard   450:   Revision 1.138  2010/04/30 18:19:40  brouard
                    451:   *** empty log message ***
                    452: 
1.138     brouard   453:   Revision 1.137  2010/04/29 18:11:38  brouard
                    454:   (Module): Checking covariates for more complex models
                    455:   than V1+V2. A lot of change to be done. Unstable.
                    456: 
1.137     brouard   457:   Revision 1.136  2010/04/26 20:30:53  brouard
                    458:   (Module): merging some libgsl code. Fixing computation
                    459:   of likelione (using inter/intrapolation if mle = 0) in order to
                    460:   get same likelihood as if mle=1.
                    461:   Some cleaning of code and comments added.
                    462: 
1.136     brouard   463:   Revision 1.135  2009/10/29 15:33:14  brouard
                    464:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    465: 
1.135     brouard   466:   Revision 1.134  2009/10/29 13:18:53  brouard
                    467:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    468: 
1.134     brouard   469:   Revision 1.133  2009/07/06 10:21:25  brouard
                    470:   just nforces
                    471: 
1.133     brouard   472:   Revision 1.132  2009/07/06 08:22:05  brouard
                    473:   Many tings
                    474: 
1.132     brouard   475:   Revision 1.131  2009/06/20 16:22:47  brouard
                    476:   Some dimensions resccaled
                    477: 
1.131     brouard   478:   Revision 1.130  2009/05/26 06:44:34  brouard
                    479:   (Module): Max Covariate is now set to 20 instead of 8. A
                    480:   lot of cleaning with variables initialized to 0. Trying to make
                    481:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    482: 
1.130     brouard   483:   Revision 1.129  2007/08/31 13:49:27  lievre
                    484:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    485: 
1.129     lievre    486:   Revision 1.128  2006/06/30 13:02:05  brouard
                    487:   (Module): Clarifications on computing e.j
                    488: 
1.128     brouard   489:   Revision 1.127  2006/04/28 18:11:50  brouard
                    490:   (Module): Yes the sum of survivors was wrong since
                    491:   imach-114 because nhstepm was no more computed in the age
                    492:   loop. Now we define nhstepma in the age loop.
                    493:   (Module): In order to speed up (in case of numerous covariates) we
                    494:   compute health expectancies (without variances) in a first step
                    495:   and then all the health expectancies with variances or standard
                    496:   deviation (needs data from the Hessian matrices) which slows the
                    497:   computation.
                    498:   In the future we should be able to stop the program is only health
                    499:   expectancies and graph are needed without standard deviations.
                    500: 
1.127     brouard   501:   Revision 1.126  2006/04/28 17:23:28  brouard
                    502:   (Module): Yes the sum of survivors was wrong since
                    503:   imach-114 because nhstepm was no more computed in the age
                    504:   loop. Now we define nhstepma in the age loop.
                    505:   Version 0.98h
                    506: 
1.126     brouard   507:   Revision 1.125  2006/04/04 15:20:31  lievre
                    508:   Errors in calculation of health expectancies. Age was not initialized.
                    509:   Forecasting file added.
                    510: 
                    511:   Revision 1.124  2006/03/22 17:13:53  lievre
                    512:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    513:   The log-likelihood is printed in the log file
                    514: 
                    515:   Revision 1.123  2006/03/20 10:52:43  brouard
                    516:   * imach.c (Module): <title> changed, corresponds to .htm file
                    517:   name. <head> headers where missing.
                    518: 
                    519:   * imach.c (Module): Weights can have a decimal point as for
                    520:   English (a comma might work with a correct LC_NUMERIC environment,
                    521:   otherwise the weight is truncated).
                    522:   Modification of warning when the covariates values are not 0 or
                    523:   1.
                    524:   Version 0.98g
                    525: 
                    526:   Revision 1.122  2006/03/20 09:45:41  brouard
                    527:   (Module): Weights can have a decimal point as for
                    528:   English (a comma might work with a correct LC_NUMERIC environment,
                    529:   otherwise the weight is truncated).
                    530:   Modification of warning when the covariates values are not 0 or
                    531:   1.
                    532:   Version 0.98g
                    533: 
                    534:   Revision 1.121  2006/03/16 17:45:01  lievre
                    535:   * imach.c (Module): Comments concerning covariates added
                    536: 
                    537:   * imach.c (Module): refinements in the computation of lli if
                    538:   status=-2 in order to have more reliable computation if stepm is
                    539:   not 1 month. Version 0.98f
                    540: 
                    541:   Revision 1.120  2006/03/16 15:10:38  lievre
                    542:   (Module): refinements in the computation of lli if
                    543:   status=-2 in order to have more reliable computation if stepm is
                    544:   not 1 month. Version 0.98f
                    545: 
                    546:   Revision 1.119  2006/03/15 17:42:26  brouard
                    547:   (Module): Bug if status = -2, the loglikelihood was
                    548:   computed as likelihood omitting the logarithm. Version O.98e
                    549: 
                    550:   Revision 1.118  2006/03/14 18:20:07  brouard
                    551:   (Module): varevsij Comments added explaining the second
                    552:   table of variances if popbased=1 .
                    553:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    554:   (Module): Function pstamp added
                    555:   (Module): Version 0.98d
                    556: 
                    557:   Revision 1.117  2006/03/14 17:16:22  brouard
                    558:   (Module): varevsij Comments added explaining the second
                    559:   table of variances if popbased=1 .
                    560:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    561:   (Module): Function pstamp added
                    562:   (Module): Version 0.98d
                    563: 
                    564:   Revision 1.116  2006/03/06 10:29:27  brouard
                    565:   (Module): Variance-covariance wrong links and
                    566:   varian-covariance of ej. is needed (Saito).
                    567: 
                    568:   Revision 1.115  2006/02/27 12:17:45  brouard
                    569:   (Module): One freematrix added in mlikeli! 0.98c
                    570: 
                    571:   Revision 1.114  2006/02/26 12:57:58  brouard
                    572:   (Module): Some improvements in processing parameter
                    573:   filename with strsep.
                    574: 
                    575:   Revision 1.113  2006/02/24 14:20:24  brouard
                    576:   (Module): Memory leaks checks with valgrind and:
                    577:   datafile was not closed, some imatrix were not freed and on matrix
                    578:   allocation too.
                    579: 
                    580:   Revision 1.112  2006/01/30 09:55:26  brouard
                    581:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    582: 
                    583:   Revision 1.111  2006/01/25 20:38:18  brouard
                    584:   (Module): Lots of cleaning and bugs added (Gompertz)
                    585:   (Module): Comments can be added in data file. Missing date values
                    586:   can be a simple dot '.'.
                    587: 
                    588:   Revision 1.110  2006/01/25 00:51:50  brouard
                    589:   (Module): Lots of cleaning and bugs added (Gompertz)
                    590: 
                    591:   Revision 1.109  2006/01/24 19:37:15  brouard
                    592:   (Module): Comments (lines starting with a #) are allowed in data.
                    593: 
                    594:   Revision 1.108  2006/01/19 18:05:42  lievre
                    595:   Gnuplot problem appeared...
                    596:   To be fixed
                    597: 
                    598:   Revision 1.107  2006/01/19 16:20:37  brouard
                    599:   Test existence of gnuplot in imach path
                    600: 
                    601:   Revision 1.106  2006/01/19 13:24:36  brouard
                    602:   Some cleaning and links added in html output
                    603: 
                    604:   Revision 1.105  2006/01/05 20:23:19  lievre
                    605:   *** empty log message ***
                    606: 
                    607:   Revision 1.104  2005/09/30 16:11:43  lievre
                    608:   (Module): sump fixed, loop imx fixed, and simplifications.
                    609:   (Module): If the status is missing at the last wave but we know
                    610:   that the person is alive, then we can code his/her status as -2
                    611:   (instead of missing=-1 in earlier versions) and his/her
                    612:   contributions to the likelihood is 1 - Prob of dying from last
                    613:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    614:   the healthy state at last known wave). Version is 0.98
                    615: 
                    616:   Revision 1.103  2005/09/30 15:54:49  lievre
                    617:   (Module): sump fixed, loop imx fixed, and simplifications.
                    618: 
                    619:   Revision 1.102  2004/09/15 17:31:30  brouard
                    620:   Add the possibility to read data file including tab characters.
                    621: 
                    622:   Revision 1.101  2004/09/15 10:38:38  brouard
                    623:   Fix on curr_time
                    624: 
                    625:   Revision 1.100  2004/07/12 18:29:06  brouard
                    626:   Add version for Mac OS X. Just define UNIX in Makefile
                    627: 
                    628:   Revision 1.99  2004/06/05 08:57:40  brouard
                    629:   *** empty log message ***
                    630: 
                    631:   Revision 1.98  2004/05/16 15:05:56  brouard
                    632:   New version 0.97 . First attempt to estimate force of mortality
                    633:   directly from the data i.e. without the need of knowing the health
                    634:   state at each age, but using a Gompertz model: log u =a + b*age .
                    635:   This is the basic analysis of mortality and should be done before any
                    636:   other analysis, in order to test if the mortality estimated from the
                    637:   cross-longitudinal survey is different from the mortality estimated
                    638:   from other sources like vital statistic data.
                    639: 
                    640:   The same imach parameter file can be used but the option for mle should be -3.
                    641: 
1.133     brouard   642:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   643:   former routines in order to include the new code within the former code.
                    644: 
                    645:   The output is very simple: only an estimate of the intercept and of
                    646:   the slope with 95% confident intervals.
                    647: 
                    648:   Current limitations:
                    649:   A) Even if you enter covariates, i.e. with the
                    650:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    651:   B) There is no computation of Life Expectancy nor Life Table.
                    652: 
                    653:   Revision 1.97  2004/02/20 13:25:42  lievre
                    654:   Version 0.96d. Population forecasting command line is (temporarily)
                    655:   suppressed.
                    656: 
                    657:   Revision 1.96  2003/07/15 15:38:55  brouard
                    658:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    659:   rewritten within the same printf. Workaround: many printfs.
                    660: 
                    661:   Revision 1.95  2003/07/08 07:54:34  brouard
                    662:   * imach.c (Repository):
                    663:   (Repository): Using imachwizard code to output a more meaningful covariance
                    664:   matrix (cov(a12,c31) instead of numbers.
                    665: 
                    666:   Revision 1.94  2003/06/27 13:00:02  brouard
                    667:   Just cleaning
                    668: 
                    669:   Revision 1.93  2003/06/25 16:33:55  brouard
                    670:   (Module): On windows (cygwin) function asctime_r doesn't
                    671:   exist so I changed back to asctime which exists.
                    672:   (Module): Version 0.96b
                    673: 
                    674:   Revision 1.92  2003/06/25 16:30:45  brouard
                    675:   (Module): On windows (cygwin) function asctime_r doesn't
                    676:   exist so I changed back to asctime which exists.
                    677: 
                    678:   Revision 1.91  2003/06/25 15:30:29  brouard
                    679:   * imach.c (Repository): Duplicated warning errors corrected.
                    680:   (Repository): Elapsed time after each iteration is now output. It
                    681:   helps to forecast when convergence will be reached. Elapsed time
                    682:   is stamped in powell.  We created a new html file for the graphs
                    683:   concerning matrix of covariance. It has extension -cov.htm.
                    684: 
                    685:   Revision 1.90  2003/06/24 12:34:15  brouard
                    686:   (Module): Some bugs corrected for windows. Also, when
                    687:   mle=-1 a template is output in file "or"mypar.txt with the design
                    688:   of the covariance matrix to be input.
                    689: 
                    690:   Revision 1.89  2003/06/24 12:30:52  brouard
                    691:   (Module): Some bugs corrected for windows. Also, when
                    692:   mle=-1 a template is output in file "or"mypar.txt with the design
                    693:   of the covariance matrix to be input.
                    694: 
                    695:   Revision 1.88  2003/06/23 17:54:56  brouard
                    696:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    697: 
                    698:   Revision 1.87  2003/06/18 12:26:01  brouard
                    699:   Version 0.96
                    700: 
                    701:   Revision 1.86  2003/06/17 20:04:08  brouard
                    702:   (Module): Change position of html and gnuplot routines and added
                    703:   routine fileappend.
                    704: 
                    705:   Revision 1.85  2003/06/17 13:12:43  brouard
                    706:   * imach.c (Repository): Check when date of death was earlier that
                    707:   current date of interview. It may happen when the death was just
                    708:   prior to the death. In this case, dh was negative and likelihood
                    709:   was wrong (infinity). We still send an "Error" but patch by
                    710:   assuming that the date of death was just one stepm after the
                    711:   interview.
                    712:   (Repository): Because some people have very long ID (first column)
                    713:   we changed int to long in num[] and we added a new lvector for
                    714:   memory allocation. But we also truncated to 8 characters (left
                    715:   truncation)
                    716:   (Repository): No more line truncation errors.
                    717: 
                    718:   Revision 1.84  2003/06/13 21:44:43  brouard
                    719:   * imach.c (Repository): Replace "freqsummary" at a correct
                    720:   place. It differs from routine "prevalence" which may be called
                    721:   many times. Probs is memory consuming and must be used with
                    722:   parcimony.
                    723:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    724: 
                    725:   Revision 1.83  2003/06/10 13:39:11  lievre
                    726:   *** empty log message ***
                    727: 
                    728:   Revision 1.82  2003/06/05 15:57:20  brouard
                    729:   Add log in  imach.c and  fullversion number is now printed.
                    730: 
                    731: */
                    732: /*
                    733:    Interpolated Markov Chain
                    734: 
                    735:   Short summary of the programme:
                    736:   
1.227     brouard   737:   This program computes Healthy Life Expectancies or State-specific
                    738:   (if states aren't health statuses) Expectancies from
                    739:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    740: 
                    741:   -1- a first survey ("cross") where individuals from different ages
                    742:   are interviewed on their health status or degree of disability (in
                    743:   the case of a health survey which is our main interest)
                    744: 
                    745:   -2- at least a second wave of interviews ("longitudinal") which
                    746:   measure each change (if any) in individual health status.  Health
                    747:   expectancies are computed from the time spent in each health state
                    748:   according to a model. More health states you consider, more time is
                    749:   necessary to reach the Maximum Likelihood of the parameters involved
                    750:   in the model.  The simplest model is the multinomial logistic model
                    751:   where pij is the probability to be observed in state j at the second
                    752:   wave conditional to be observed in state i at the first
                    753:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    754:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    755:   have a more complex model than "constant and age", you should modify
                    756:   the program where the markup *Covariates have to be included here
                    757:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   758:   convergence.
                    759: 
                    760:   The advantage of this computer programme, compared to a simple
                    761:   multinomial logistic model, is clear when the delay between waves is not
                    762:   identical for each individual. Also, if a individual missed an
                    763:   intermediate interview, the information is lost, but taken into
                    764:   account using an interpolation or extrapolation.  
                    765: 
                    766:   hPijx is the probability to be observed in state i at age x+h
                    767:   conditional to the observed state i at age x. The delay 'h' can be
                    768:   split into an exact number (nh*stepm) of unobserved intermediate
                    769:   states. This elementary transition (by month, quarter,
                    770:   semester or year) is modelled as a multinomial logistic.  The hPx
                    771:   matrix is simply the matrix product of nh*stepm elementary matrices
                    772:   and the contribution of each individual to the likelihood is simply
                    773:   hPijx.
                    774: 
                    775:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   776:   of the life expectancies. It also computes the period (stable) prevalence.
                    777: 
                    778: Back prevalence and projections:
1.227     brouard   779: 
                    780:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    781:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    782:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    783:    mobilavproj)
                    784: 
                    785:     Computes the back prevalence limit for any combination of
                    786:     covariate values k at any age between ageminpar and agemaxpar and
                    787:     returns it in **bprlim. In the loops,
                    788: 
                    789:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    790:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    791: 
                    792:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   793:    Computes for any combination of covariates k and any age between bage and fage 
                    794:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    795:                        oldm=oldms;savm=savms;
1.227     brouard   796: 
                    797:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   798:      Computes the transition matrix starting at age 'age' over
                    799:      'nhstepm*hstepm*stepm' months (i.e. until
                    800:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   801:      nhstepm*hstepm matrices. 
                    802: 
                    803:      Returns p3mat[i][j][h] after calling
                    804:      p3mat[i][j][h]=matprod2(newm,
                    805:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    806:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    807:      oldm);
1.226     brouard   808: 
                    809: Important routines
                    810: 
                    811: - func (or funcone), computes logit (pij) distinguishing
                    812:   o fixed variables (single or product dummies or quantitative);
                    813:   o varying variables by:
                    814:    (1) wave (single, product dummies, quantitative), 
                    815:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    816:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    817:        % varying dummy (not done) or quantitative (not done);
                    818: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    819:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    820: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    821:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    822:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   823: 
1.226     brouard   824: 
                    825:   
1.133     brouard   826:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    827:            Institut national d'études démographiques, Paris.
1.126     brouard   828:   This software have been partly granted by Euro-REVES, a concerted action
                    829:   from the European Union.
                    830:   It is copyrighted identically to a GNU software product, ie programme and
                    831:   software can be distributed freely for non commercial use. Latest version
                    832:   can be accessed at http://euroreves.ined.fr/imach .
                    833: 
                    834:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    835:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    836:   
                    837:   **********************************************************************/
                    838: /*
                    839:   main
                    840:   read parameterfile
                    841:   read datafile
                    842:   concatwav
                    843:   freqsummary
                    844:   if (mle >= 1)
                    845:     mlikeli
                    846:   print results files
                    847:   if mle==1 
                    848:      computes hessian
                    849:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    850:       begin-prev-date,...
                    851:   open gnuplot file
                    852:   open html file
1.145     brouard   853:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    854:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    855:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    856:     freexexit2 possible for memory heap.
                    857: 
                    858:   h Pij x                         | pij_nom  ficrestpij
                    859:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    860:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    861:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    862: 
                    863:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    864:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    865:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    866:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    867:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    868: 
1.126     brouard   869:   forecasting if prevfcast==1 prevforecast call prevalence()
                    870:   health expectancies
                    871:   Variance-covariance of DFLE
                    872:   prevalence()
                    873:    movingaverage()
                    874:   varevsij() 
                    875:   if popbased==1 varevsij(,popbased)
                    876:   total life expectancies
                    877:   Variance of period (stable) prevalence
                    878:  end
                    879: */
                    880: 
1.187     brouard   881: /* #define DEBUG */
                    882: /* #define DEBUGBRENT */
1.203     brouard   883: /* #define DEBUGLINMIN */
                    884: /* #define DEBUGHESS */
                    885: #define DEBUGHESSIJ
1.224     brouard   886: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   887: #define POWELL /* Instead of NLOPT */
1.224     brouard   888: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   889: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    890: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   891: 
                    892: #include <math.h>
                    893: #include <stdio.h>
                    894: #include <stdlib.h>
                    895: #include <string.h>
1.226     brouard   896: #include <ctype.h>
1.159     brouard   897: 
                    898: #ifdef _WIN32
                    899: #include <io.h>
1.172     brouard   900: #include <windows.h>
                    901: #include <tchar.h>
1.159     brouard   902: #else
1.126     brouard   903: #include <unistd.h>
1.159     brouard   904: #endif
1.126     brouard   905: 
                    906: #include <limits.h>
                    907: #include <sys/types.h>
1.171     brouard   908: 
                    909: #if defined(__GNUC__)
                    910: #include <sys/utsname.h> /* Doesn't work on Windows */
                    911: #endif
                    912: 
1.126     brouard   913: #include <sys/stat.h>
                    914: #include <errno.h>
1.159     brouard   915: /* extern int errno; */
1.126     brouard   916: 
1.157     brouard   917: /* #ifdef LINUX */
                    918: /* #include <time.h> */
                    919: /* #include "timeval.h" */
                    920: /* #else */
                    921: /* #include <sys/time.h> */
                    922: /* #endif */
                    923: 
1.126     brouard   924: #include <time.h>
                    925: 
1.136     brouard   926: #ifdef GSL
                    927: #include <gsl/gsl_errno.h>
                    928: #include <gsl/gsl_multimin.h>
                    929: #endif
                    930: 
1.167     brouard   931: 
1.162     brouard   932: #ifdef NLOPT
                    933: #include <nlopt.h>
                    934: typedef struct {
                    935:   double (* function)(double [] );
                    936: } myfunc_data ;
                    937: #endif
                    938: 
1.126     brouard   939: /* #include <libintl.h> */
                    940: /* #define _(String) gettext (String) */
                    941: 
1.251     brouard   942: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   943: 
                    944: #define GNUPLOTPROGRAM "gnuplot"
                    945: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    946: #define FILENAMELENGTH 132
                    947: 
                    948: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    949: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    950: 
1.144     brouard   951: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    952: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   953: 
                    954: #define NINTERVMAX 8
1.144     brouard   955: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    956: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    957: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   958: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   959: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    960: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   961: #define MAXN 20000
1.144     brouard   962: #define YEARM 12. /**< Number of months per year */
1.218     brouard   963: /* #define AGESUP 130 */
                    964: #define AGESUP 150
                    965: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   966: #define AGEBASE 40
1.194     brouard   967: #define AGEOVERFLOW 1.e20
1.164     brouard   968: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   969: #ifdef _WIN32
                    970: #define DIRSEPARATOR '\\'
                    971: #define CHARSEPARATOR "\\"
                    972: #define ODIRSEPARATOR '/'
                    973: #else
1.126     brouard   974: #define DIRSEPARATOR '/'
                    975: #define CHARSEPARATOR "/"
                    976: #define ODIRSEPARATOR '\\'
                    977: #endif
                    978: 
1.259   ! brouard   979: /* $Id: imach.c,v 1.258 2017/04/03 10:17:47 brouard Exp $ */
1.126     brouard   980: /* $State: Exp $ */
1.196     brouard   981: #include "version.h"
                    982: char version[]=__IMACH_VERSION__;
1.224     brouard   983: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.259   ! brouard   984: char fullversion[]="$Revision: 1.258 $ $Date: 2017/04/03 10:17:47 $"; 
1.126     brouard   985: char strstart[80];
                    986: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   987: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   988: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   989: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    990: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    991: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   992: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    993: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   994: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    995: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    996: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   997: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    998: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   999: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1000: int nsd=0; /**< Total number of single dummy variables (output) */
                   1001: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1002: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1003: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1004: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1005: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1006: int cptcov=0; /* Working variable */
1.218     brouard  1007: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1008: int npar=NPARMAX;
                   1009: int nlstate=2; /* Number of live states */
                   1010: int ndeath=1; /* Number of dead states */
1.130     brouard  1011: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1012: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1013: int popbased=0;
                   1014: 
                   1015: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1016: int maxwav=0; /* Maxim number of waves */
                   1017: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1018: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1019: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1020:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1021: int mle=1, weightopt=0;
1.126     brouard  1022: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1023: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1024: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1025:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1026: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1027: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1028: 
1.130     brouard  1029: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1030: double **matprod2(); /* test */
1.126     brouard  1031: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1032: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1033: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1034: 
1.136     brouard  1035: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1036: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1037: FILE *ficlog, *ficrespow;
1.130     brouard  1038: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1039: double fretone; /* Only one call to likelihood */
1.130     brouard  1040: long ipmx=0; /* Number of contributions */
1.126     brouard  1041: double sw; /* Sum of weights */
                   1042: char filerespow[FILENAMELENGTH];
                   1043: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1044: FILE *ficresilk;
                   1045: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1046: FILE *ficresprobmorprev;
                   1047: FILE *fichtm, *fichtmcov; /* Html File */
                   1048: FILE *ficreseij;
                   1049: char filerese[FILENAMELENGTH];
                   1050: FILE *ficresstdeij;
                   1051: char fileresstde[FILENAMELENGTH];
                   1052: FILE *ficrescveij;
                   1053: char filerescve[FILENAMELENGTH];
                   1054: FILE  *ficresvij;
                   1055: char fileresv[FILENAMELENGTH];
                   1056: FILE  *ficresvpl;
                   1057: char fileresvpl[FILENAMELENGTH];
                   1058: char title[MAXLINE];
1.234     brouard  1059: char model[MAXLINE]; /**< The model line */
1.217     brouard  1060: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1061: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1062: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1063: char command[FILENAMELENGTH];
                   1064: int  outcmd=0;
                   1065: 
1.217     brouard  1066: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1067: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1068: char filelog[FILENAMELENGTH]; /* Log file */
                   1069: char filerest[FILENAMELENGTH];
                   1070: char fileregp[FILENAMELENGTH];
                   1071: char popfile[FILENAMELENGTH];
                   1072: 
                   1073: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1074: 
1.157     brouard  1075: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1076: /* struct timezone tzp; */
                   1077: /* extern int gettimeofday(); */
                   1078: struct tm tml, *gmtime(), *localtime();
                   1079: 
                   1080: extern time_t time();
                   1081: 
                   1082: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1083: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1084: struct tm tm;
                   1085: 
1.126     brouard  1086: char strcurr[80], strfor[80];
                   1087: 
                   1088: char *endptr;
                   1089: long lval;
                   1090: double dval;
                   1091: 
                   1092: #define NR_END 1
                   1093: #define FREE_ARG char*
                   1094: #define FTOL 1.0e-10
                   1095: 
                   1096: #define NRANSI 
1.240     brouard  1097: #define ITMAX 200
                   1098: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1099: 
                   1100: #define TOL 2.0e-4 
                   1101: 
                   1102: #define CGOLD 0.3819660 
                   1103: #define ZEPS 1.0e-10 
                   1104: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1105: 
                   1106: #define GOLD 1.618034 
                   1107: #define GLIMIT 100.0 
                   1108: #define TINY 1.0e-20 
                   1109: 
                   1110: static double maxarg1,maxarg2;
                   1111: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1112: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1113:   
                   1114: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1115: #define rint(a) floor(a+0.5)
1.166     brouard  1116: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1117: #define mytinydouble 1.0e-16
1.166     brouard  1118: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1119: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1120: /* static double dsqrarg; */
                   1121: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1122: static double sqrarg;
                   1123: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1124: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1125: int agegomp= AGEGOMP;
                   1126: 
                   1127: int imx; 
                   1128: int stepm=1;
                   1129: /* Stepm, step in month: minimum step interpolation*/
                   1130: 
                   1131: int estepm;
                   1132: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1133: 
                   1134: int m,nb;
                   1135: long *num;
1.197     brouard  1136: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1137: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1138:                   covariate for which somebody answered excluding 
                   1139:                   undefined. Usually 2: 0 and 1. */
                   1140: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1141:                             covariate for which somebody answered including 
                   1142:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1143: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1144: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1145: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1146: double *ageexmed,*agecens;
                   1147: double dateintmean=0;
                   1148: 
                   1149: double *weight;
                   1150: int **s; /* Status */
1.141     brouard  1151: double *agedc;
1.145     brouard  1152: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1153:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1154:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1155: double **coqvar; /* Fixed quantitative covariate iqv */
                   1156: double ***cotvar; /* Time varying covariate itv */
                   1157: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1158: double  idx; 
                   1159: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1160: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1161: /*k          1  2   3   4     5    6    7     8    9 */
                   1162: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1163: /* Tndvar[k]    1   2   3               4          5 */
                   1164: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1165: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1166: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1167: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1168: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1169: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1170: /* Tprod[i]=k           4               7            */
                   1171: /* Tage[i]=k                  5               8      */
                   1172: /* */
                   1173: /* Type                    */
                   1174: /* V         1  2  3  4  5 */
                   1175: /*           F  F  V  V  V */
                   1176: /*           D  Q  D  D  Q */
                   1177: /*                         */
                   1178: int *TvarsD;
                   1179: int *TvarsDind;
                   1180: int *TvarsQ;
                   1181: int *TvarsQind;
                   1182: 
1.235     brouard  1183: #define MAXRESULTLINES 10
                   1184: int nresult=0;
1.258     brouard  1185: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1186: int TKresult[MAXRESULTLINES];
1.237     brouard  1187: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1188: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1189: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1190: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1191: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1192: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1193: 
1.234     brouard  1194: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1195: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1196: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1197: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1198: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1199: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1200: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1201: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1202: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1203: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1204: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1205: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1206: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1207: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1208: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1209: 
1.230     brouard  1210: int *Tvarsel; /**< Selected covariates for output */
                   1211: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1212: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1213: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1214: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1215: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1216: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1217: int *Tage;
1.227     brouard  1218: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1219: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1220: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1221: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1222: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1223: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1224: int **Tvard;
                   1225: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1226: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1227: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1228:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1229:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1230: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1231: double *lsurv, *lpop, *tpop;
                   1232: 
1.231     brouard  1233: #define FD 1; /* Fixed dummy covariate */
                   1234: #define FQ 2; /* Fixed quantitative covariate */
                   1235: #define FP 3; /* Fixed product covariate */
                   1236: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1237: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1238: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1239: #define VD 10; /* Varying dummy covariate */
                   1240: #define VQ 11; /* Varying quantitative covariate */
                   1241: #define VP 12; /* Varying product covariate */
                   1242: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1243: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1244: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1245: #define APFD 16; /* Age product * fixed dummy covariate */
                   1246: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1247: #define APVD 18; /* Age product * varying dummy covariate */
                   1248: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1249: 
                   1250: #define FTYPE 1; /* Fixed covariate */
                   1251: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1252: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1253: 
                   1254: struct kmodel{
                   1255:        int maintype; /* main type */
                   1256:        int subtype; /* subtype */
                   1257: };
                   1258: struct kmodel modell[NCOVMAX];
                   1259: 
1.143     brouard  1260: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1261: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1262: 
                   1263: /**************** split *************************/
                   1264: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1265: {
                   1266:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1267:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1268:   */ 
                   1269:   char *ss;                            /* pointer */
1.186     brouard  1270:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1271: 
                   1272:   l1 = strlen(path );                  /* length of path */
                   1273:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1274:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1275:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1276:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1277:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1278:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1279:     /* get current working directory */
                   1280:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1281: #ifdef WIN32
                   1282:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1283: #else
                   1284:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1285: #endif
1.126     brouard  1286:       return( GLOCK_ERROR_GETCWD );
                   1287:     }
                   1288:     /* got dirc from getcwd*/
                   1289:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1290:   } else {                             /* strip directory from path */
1.126     brouard  1291:     ss++;                              /* after this, the filename */
                   1292:     l2 = strlen( ss );                 /* length of filename */
                   1293:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1294:     strcpy( name, ss );                /* save file name */
                   1295:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1296:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1297:     printf(" DIRC2 = %s \n",dirc);
                   1298:   }
                   1299:   /* We add a separator at the end of dirc if not exists */
                   1300:   l1 = strlen( dirc );                 /* length of directory */
                   1301:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1302:     dirc[l1] =  DIRSEPARATOR;
                   1303:     dirc[l1+1] = 0; 
                   1304:     printf(" DIRC3 = %s \n",dirc);
                   1305:   }
                   1306:   ss = strrchr( name, '.' );           /* find last / */
                   1307:   if (ss >0){
                   1308:     ss++;
                   1309:     strcpy(ext,ss);                    /* save extension */
                   1310:     l1= strlen( name);
                   1311:     l2= strlen(ss)+1;
                   1312:     strncpy( finame, name, l1-l2);
                   1313:     finame[l1-l2]= 0;
                   1314:   }
                   1315: 
                   1316:   return( 0 );                         /* we're done */
                   1317: }
                   1318: 
                   1319: 
                   1320: /******************************************/
                   1321: 
                   1322: void replace_back_to_slash(char *s, char*t)
                   1323: {
                   1324:   int i;
                   1325:   int lg=0;
                   1326:   i=0;
                   1327:   lg=strlen(t);
                   1328:   for(i=0; i<= lg; i++) {
                   1329:     (s[i] = t[i]);
                   1330:     if (t[i]== '\\') s[i]='/';
                   1331:   }
                   1332: }
                   1333: 
1.132     brouard  1334: char *trimbb(char *out, char *in)
1.137     brouard  1335: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1336:   char *s;
                   1337:   s=out;
                   1338:   while (*in != '\0'){
1.137     brouard  1339:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1340:       in++;
                   1341:     }
                   1342:     *out++ = *in++;
                   1343:   }
                   1344:   *out='\0';
                   1345:   return s;
                   1346: }
                   1347: 
1.187     brouard  1348: /* char *substrchaine(char *out, char *in, char *chain) */
                   1349: /* { */
                   1350: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1351: /*   char *s, *t; */
                   1352: /*   t=in;s=out; */
                   1353: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1354: /*     *out++ = *in++; */
                   1355: /*   } */
                   1356: 
                   1357: /*   /\* *in matches *chain *\/ */
                   1358: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1359: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1360: /*   } */
                   1361: /*   in--; chain--; */
                   1362: /*   while ( (*in != '\0')){ */
                   1363: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1364: /*     *out++ = *in++; */
                   1365: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1366: /*   } */
                   1367: /*   *out='\0'; */
                   1368: /*   out=s; */
                   1369: /*   return out; */
                   1370: /* } */
                   1371: char *substrchaine(char *out, char *in, char *chain)
                   1372: {
                   1373:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1374:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1375: 
                   1376:   char *strloc;
                   1377: 
                   1378:   strcpy (out, in); 
                   1379:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1380:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1381:   if(strloc != NULL){ 
                   1382:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1383:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1384:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1385:   }
                   1386:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1387:   return out;
                   1388: }
                   1389: 
                   1390: 
1.145     brouard  1391: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1392: {
1.187     brouard  1393:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1394:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1395:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1396:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1397:   */
1.160     brouard  1398:   char *s, *t;
1.145     brouard  1399:   t=in;s=in;
                   1400:   while ((*in != occ) && (*in != '\0')){
                   1401:     *alocc++ = *in++;
                   1402:   }
                   1403:   if( *in == occ){
                   1404:     *(alocc)='\0';
                   1405:     s=++in;
                   1406:   }
                   1407:  
                   1408:   if (s == t) {/* occ not found */
                   1409:     *(alocc-(in-s))='\0';
                   1410:     in=s;
                   1411:   }
                   1412:   while ( *in != '\0'){
                   1413:     *blocc++ = *in++;
                   1414:   }
                   1415: 
                   1416:   *blocc='\0';
                   1417:   return t;
                   1418: }
1.137     brouard  1419: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1420: {
1.187     brouard  1421:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1422:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1423:      gives blocc="abcdef2ghi" and alocc="j".
                   1424:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1425:   */
                   1426:   char *s, *t;
                   1427:   t=in;s=in;
                   1428:   while (*in != '\0'){
                   1429:     while( *in == occ){
                   1430:       *blocc++ = *in++;
                   1431:       s=in;
                   1432:     }
                   1433:     *blocc++ = *in++;
                   1434:   }
                   1435:   if (s == t) /* occ not found */
                   1436:     *(blocc-(in-s))='\0';
                   1437:   else
                   1438:     *(blocc-(in-s)-1)='\0';
                   1439:   in=s;
                   1440:   while ( *in != '\0'){
                   1441:     *alocc++ = *in++;
                   1442:   }
                   1443: 
                   1444:   *alocc='\0';
                   1445:   return s;
                   1446: }
                   1447: 
1.126     brouard  1448: int nbocc(char *s, char occ)
                   1449: {
                   1450:   int i,j=0;
                   1451:   int lg=20;
                   1452:   i=0;
                   1453:   lg=strlen(s);
                   1454:   for(i=0; i<= lg; i++) {
1.234     brouard  1455:     if  (s[i] == occ ) j++;
1.126     brouard  1456:   }
                   1457:   return j;
                   1458: }
                   1459: 
1.137     brouard  1460: /* void cutv(char *u,char *v, char*t, char occ) */
                   1461: /* { */
                   1462: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1463: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1464: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1465: /*   int i,lg,j,p=0; */
                   1466: /*   i=0; */
                   1467: /*   lg=strlen(t); */
                   1468: /*   for(j=0; j<=lg-1; j++) { */
                   1469: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1470: /*   } */
1.126     brouard  1471: 
1.137     brouard  1472: /*   for(j=0; j<p; j++) { */
                   1473: /*     (u[j] = t[j]); */
                   1474: /*   } */
                   1475: /*      u[p]='\0'; */
1.126     brouard  1476: 
1.137     brouard  1477: /*    for(j=0; j<= lg; j++) { */
                   1478: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1479: /*   } */
                   1480: /* } */
1.126     brouard  1481: 
1.160     brouard  1482: #ifdef _WIN32
                   1483: char * strsep(char **pp, const char *delim)
                   1484: {
                   1485:   char *p, *q;
                   1486:          
                   1487:   if ((p = *pp) == NULL)
                   1488:     return 0;
                   1489:   if ((q = strpbrk (p, delim)) != NULL)
                   1490:   {
                   1491:     *pp = q + 1;
                   1492:     *q = '\0';
                   1493:   }
                   1494:   else
                   1495:     *pp = 0;
                   1496:   return p;
                   1497: }
                   1498: #endif
                   1499: 
1.126     brouard  1500: /********************** nrerror ********************/
                   1501: 
                   1502: void nrerror(char error_text[])
                   1503: {
                   1504:   fprintf(stderr,"ERREUR ...\n");
                   1505:   fprintf(stderr,"%s\n",error_text);
                   1506:   exit(EXIT_FAILURE);
                   1507: }
                   1508: /*********************** vector *******************/
                   1509: double *vector(int nl, int nh)
                   1510: {
                   1511:   double *v;
                   1512:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1513:   if (!v) nrerror("allocation failure in vector");
                   1514:   return v-nl+NR_END;
                   1515: }
                   1516: 
                   1517: /************************ free vector ******************/
                   1518: void free_vector(double*v, int nl, int nh)
                   1519: {
                   1520:   free((FREE_ARG)(v+nl-NR_END));
                   1521: }
                   1522: 
                   1523: /************************ivector *******************************/
                   1524: int *ivector(long nl,long nh)
                   1525: {
                   1526:   int *v;
                   1527:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1528:   if (!v) nrerror("allocation failure in ivector");
                   1529:   return v-nl+NR_END;
                   1530: }
                   1531: 
                   1532: /******************free ivector **************************/
                   1533: void free_ivector(int *v, long nl, long nh)
                   1534: {
                   1535:   free((FREE_ARG)(v+nl-NR_END));
                   1536: }
                   1537: 
                   1538: /************************lvector *******************************/
                   1539: long *lvector(long nl,long nh)
                   1540: {
                   1541:   long *v;
                   1542:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1543:   if (!v) nrerror("allocation failure in ivector");
                   1544:   return v-nl+NR_END;
                   1545: }
                   1546: 
                   1547: /******************free lvector **************************/
                   1548: void free_lvector(long *v, long nl, long nh)
                   1549: {
                   1550:   free((FREE_ARG)(v+nl-NR_END));
                   1551: }
                   1552: 
                   1553: /******************* imatrix *******************************/
                   1554: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1555:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1556: { 
                   1557:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1558:   int **m; 
                   1559:   
                   1560:   /* allocate pointers to rows */ 
                   1561:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1562:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1563:   m += NR_END; 
                   1564:   m -= nrl; 
                   1565:   
                   1566:   
                   1567:   /* allocate rows and set pointers to them */ 
                   1568:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1569:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1570:   m[nrl] += NR_END; 
                   1571:   m[nrl] -= ncl; 
                   1572:   
                   1573:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1574:   
                   1575:   /* return pointer to array of pointers to rows */ 
                   1576:   return m; 
                   1577: } 
                   1578: 
                   1579: /****************** free_imatrix *************************/
                   1580: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1581:       int **m;
                   1582:       long nch,ncl,nrh,nrl; 
                   1583:      /* free an int matrix allocated by imatrix() */ 
                   1584: { 
                   1585:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1586:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1587: } 
                   1588: 
                   1589: /******************* matrix *******************************/
                   1590: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1591: {
                   1592:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1593:   double **m;
                   1594: 
                   1595:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1596:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1597:   m += NR_END;
                   1598:   m -= nrl;
                   1599: 
                   1600:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1601:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1602:   m[nrl] += NR_END;
                   1603:   m[nrl] -= ncl;
                   1604: 
                   1605:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1606:   return m;
1.145     brouard  1607:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1608: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1609: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1610:    */
                   1611: }
                   1612: 
                   1613: /*************************free matrix ************************/
                   1614: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1615: {
                   1616:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1617:   free((FREE_ARG)(m+nrl-NR_END));
                   1618: }
                   1619: 
                   1620: /******************* ma3x *******************************/
                   1621: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1622: {
                   1623:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1624:   double ***m;
                   1625: 
                   1626:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1627:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1628:   m += NR_END;
                   1629:   m -= nrl;
                   1630: 
                   1631:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1632:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1633:   m[nrl] += NR_END;
                   1634:   m[nrl] -= ncl;
                   1635: 
                   1636:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1637: 
                   1638:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1639:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1640:   m[nrl][ncl] += NR_END;
                   1641:   m[nrl][ncl] -= nll;
                   1642:   for (j=ncl+1; j<=nch; j++) 
                   1643:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1644:   
                   1645:   for (i=nrl+1; i<=nrh; i++) {
                   1646:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1647:     for (j=ncl+1; j<=nch; j++) 
                   1648:       m[i][j]=m[i][j-1]+nlay;
                   1649:   }
                   1650:   return m; 
                   1651:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1652:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1653:   */
                   1654: }
                   1655: 
                   1656: /*************************free ma3x ************************/
                   1657: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1658: {
                   1659:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1660:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1661:   free((FREE_ARG)(m+nrl-NR_END));
                   1662: }
                   1663: 
                   1664: /*************** function subdirf ***********/
                   1665: char *subdirf(char fileres[])
                   1666: {
                   1667:   /* Caution optionfilefiname is hidden */
                   1668:   strcpy(tmpout,optionfilefiname);
                   1669:   strcat(tmpout,"/"); /* Add to the right */
                   1670:   strcat(tmpout,fileres);
                   1671:   return tmpout;
                   1672: }
                   1673: 
                   1674: /*************** function subdirf2 ***********/
                   1675: char *subdirf2(char fileres[], char *preop)
                   1676: {
                   1677:   
                   1678:   /* Caution optionfilefiname is hidden */
                   1679:   strcpy(tmpout,optionfilefiname);
                   1680:   strcat(tmpout,"/");
                   1681:   strcat(tmpout,preop);
                   1682:   strcat(tmpout,fileres);
                   1683:   return tmpout;
                   1684: }
                   1685: 
                   1686: /*************** function subdirf3 ***********/
                   1687: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1688: {
                   1689:   
                   1690:   /* Caution optionfilefiname is hidden */
                   1691:   strcpy(tmpout,optionfilefiname);
                   1692:   strcat(tmpout,"/");
                   1693:   strcat(tmpout,preop);
                   1694:   strcat(tmpout,preop2);
                   1695:   strcat(tmpout,fileres);
                   1696:   return tmpout;
                   1697: }
1.213     brouard  1698:  
                   1699: /*************** function subdirfext ***********/
                   1700: char *subdirfext(char fileres[], char *preop, char *postop)
                   1701: {
                   1702:   
                   1703:   strcpy(tmpout,preop);
                   1704:   strcat(tmpout,fileres);
                   1705:   strcat(tmpout,postop);
                   1706:   return tmpout;
                   1707: }
1.126     brouard  1708: 
1.213     brouard  1709: /*************** function subdirfext3 ***********/
                   1710: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1711: {
                   1712:   
                   1713:   /* Caution optionfilefiname is hidden */
                   1714:   strcpy(tmpout,optionfilefiname);
                   1715:   strcat(tmpout,"/");
                   1716:   strcat(tmpout,preop);
                   1717:   strcat(tmpout,fileres);
                   1718:   strcat(tmpout,postop);
                   1719:   return tmpout;
                   1720: }
                   1721:  
1.162     brouard  1722: char *asc_diff_time(long time_sec, char ascdiff[])
                   1723: {
                   1724:   long sec_left, days, hours, minutes;
                   1725:   days = (time_sec) / (60*60*24);
                   1726:   sec_left = (time_sec) % (60*60*24);
                   1727:   hours = (sec_left) / (60*60) ;
                   1728:   sec_left = (sec_left) %(60*60);
                   1729:   minutes = (sec_left) /60;
                   1730:   sec_left = (sec_left) % (60);
                   1731:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1732:   return ascdiff;
                   1733: }
                   1734: 
1.126     brouard  1735: /***************** f1dim *************************/
                   1736: extern int ncom; 
                   1737: extern double *pcom,*xicom;
                   1738: extern double (*nrfunc)(double []); 
                   1739:  
                   1740: double f1dim(double x) 
                   1741: { 
                   1742:   int j; 
                   1743:   double f;
                   1744:   double *xt; 
                   1745:  
                   1746:   xt=vector(1,ncom); 
                   1747:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1748:   f=(*nrfunc)(xt); 
                   1749:   free_vector(xt,1,ncom); 
                   1750:   return f; 
                   1751: } 
                   1752: 
                   1753: /*****************brent *************************/
                   1754: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1755: {
                   1756:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1757:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1758:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1759:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1760:    * returned function value. 
                   1761:   */
1.126     brouard  1762:   int iter; 
                   1763:   double a,b,d,etemp;
1.159     brouard  1764:   double fu=0,fv,fw,fx;
1.164     brouard  1765:   double ftemp=0.;
1.126     brouard  1766:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1767:   double e=0.0; 
                   1768:  
                   1769:   a=(ax < cx ? ax : cx); 
                   1770:   b=(ax > cx ? ax : cx); 
                   1771:   x=w=v=bx; 
                   1772:   fw=fv=fx=(*f)(x); 
                   1773:   for (iter=1;iter<=ITMAX;iter++) { 
                   1774:     xm=0.5*(a+b); 
                   1775:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1776:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1777:     printf(".");fflush(stdout);
                   1778:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1779: #ifdef DEBUGBRENT
1.126     brouard  1780:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1781:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1782:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1783: #endif
                   1784:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1785:       *xmin=x; 
                   1786:       return fx; 
                   1787:     } 
                   1788:     ftemp=fu;
                   1789:     if (fabs(e) > tol1) { 
                   1790:       r=(x-w)*(fx-fv); 
                   1791:       q=(x-v)*(fx-fw); 
                   1792:       p=(x-v)*q-(x-w)*r; 
                   1793:       q=2.0*(q-r); 
                   1794:       if (q > 0.0) p = -p; 
                   1795:       q=fabs(q); 
                   1796:       etemp=e; 
                   1797:       e=d; 
                   1798:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1799:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1800:       else { 
1.224     brouard  1801:                                d=p/q; 
                   1802:                                u=x+d; 
                   1803:                                if (u-a < tol2 || b-u < tol2) 
                   1804:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1805:       } 
                   1806:     } else { 
                   1807:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1808:     } 
                   1809:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1810:     fu=(*f)(u); 
                   1811:     if (fu <= fx) { 
                   1812:       if (u >= x) a=x; else b=x; 
                   1813:       SHFT(v,w,x,u) 
1.183     brouard  1814:       SHFT(fv,fw,fx,fu) 
                   1815:     } else { 
                   1816:       if (u < x) a=u; else b=u; 
                   1817:       if (fu <= fw || w == x) { 
1.224     brouard  1818:                                v=w; 
                   1819:                                w=u; 
                   1820:                                fv=fw; 
                   1821:                                fw=fu; 
1.183     brouard  1822:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1823:                                v=u; 
                   1824:                                fv=fu; 
1.183     brouard  1825:       } 
                   1826:     } 
1.126     brouard  1827:   } 
                   1828:   nrerror("Too many iterations in brent"); 
                   1829:   *xmin=x; 
                   1830:   return fx; 
                   1831: } 
                   1832: 
                   1833: /****************** mnbrak ***********************/
                   1834: 
                   1835: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1836:            double (*func)(double)) 
1.183     brouard  1837: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1838: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1839: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1840: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1841:    */
1.126     brouard  1842:   double ulim,u,r,q, dum;
                   1843:   double fu; 
1.187     brouard  1844: 
                   1845:   double scale=10.;
                   1846:   int iterscale=0;
                   1847: 
                   1848:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1849:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1850: 
                   1851: 
                   1852:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1853:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1854:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1855:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1856:   /* } */
                   1857: 
1.126     brouard  1858:   if (*fb > *fa) { 
                   1859:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1860:     SHFT(dum,*fb,*fa,dum) 
                   1861:   } 
1.126     brouard  1862:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1863:   *fc=(*func)(*cx); 
1.183     brouard  1864: #ifdef DEBUG
1.224     brouard  1865:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1866:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1867: #endif
1.224     brouard  1868:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1869:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1870:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1871:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1872:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1873:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1874:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1875:       fu=(*func)(u); 
1.163     brouard  1876: #ifdef DEBUG
                   1877:       /* f(x)=A(x-u)**2+f(u) */
                   1878:       double A, fparabu; 
                   1879:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1880:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1881:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1882:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1883:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1884:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1885:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1886:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1887: #endif 
1.184     brouard  1888: #ifdef MNBRAKORIGINAL
1.183     brouard  1889: #else
1.191     brouard  1890: /*       if (fu > *fc) { */
                   1891: /* #ifdef DEBUG */
                   1892: /*       printf("mnbrak4  fu > fc \n"); */
                   1893: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1894: /* #endif */
                   1895: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1896: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1897: /*     dum=u; /\* Shifting c and u *\/ */
                   1898: /*     u = *cx; */
                   1899: /*     *cx = dum; */
                   1900: /*     dum = fu; */
                   1901: /*     fu = *fc; */
                   1902: /*     *fc =dum; */
                   1903: /*       } else { /\* end *\/ */
                   1904: /* #ifdef DEBUG */
                   1905: /*       printf("mnbrak3  fu < fc \n"); */
                   1906: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1907: /* #endif */
                   1908: /*     dum=u; /\* Shifting c and u *\/ */
                   1909: /*     u = *cx; */
                   1910: /*     *cx = dum; */
                   1911: /*     dum = fu; */
                   1912: /*     fu = *fc; */
                   1913: /*     *fc =dum; */
                   1914: /*       } */
1.224     brouard  1915: #ifdef DEBUGMNBRAK
                   1916:                 double A, fparabu; 
                   1917:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1918:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1919:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1920:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1921: #endif
1.191     brouard  1922:       dum=u; /* Shifting c and u */
                   1923:       u = *cx;
                   1924:       *cx = dum;
                   1925:       dum = fu;
                   1926:       fu = *fc;
                   1927:       *fc =dum;
1.183     brouard  1928: #endif
1.162     brouard  1929:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1930: #ifdef DEBUG
1.224     brouard  1931:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1932:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1933: #endif
1.126     brouard  1934:       fu=(*func)(u); 
                   1935:       if (fu < *fc) { 
1.183     brouard  1936: #ifdef DEBUG
1.224     brouard  1937:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1938:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1939: #endif
                   1940:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1941:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1942: #ifdef DEBUG
                   1943:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1944: #endif
                   1945:       } 
1.162     brouard  1946:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1947: #ifdef DEBUG
1.224     brouard  1948:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1949:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1950: #endif
1.126     brouard  1951:       u=ulim; 
                   1952:       fu=(*func)(u); 
1.183     brouard  1953:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1954: #ifdef DEBUG
1.224     brouard  1955:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1956:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1957: #endif
1.126     brouard  1958:       u=(*cx)+GOLD*(*cx-*bx); 
                   1959:       fu=(*func)(u); 
1.224     brouard  1960: #ifdef DEBUG
                   1961:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1962:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1963: #endif
1.183     brouard  1964:     } /* end tests */
1.126     brouard  1965:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1966:     SHFT(*fa,*fb,*fc,fu) 
                   1967: #ifdef DEBUG
1.224     brouard  1968:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1969:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1970: #endif
                   1971:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1972: } 
                   1973: 
                   1974: /*************** linmin ************************/
1.162     brouard  1975: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1976: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1977: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1978: the value of func at the returned location p . This is actually all accomplished by calling the
                   1979: routines mnbrak and brent .*/
1.126     brouard  1980: int ncom; 
                   1981: double *pcom,*xicom;
                   1982: double (*nrfunc)(double []); 
                   1983:  
1.224     brouard  1984: #ifdef LINMINORIGINAL
1.126     brouard  1985: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1986: #else
                   1987: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1988: #endif
1.126     brouard  1989: { 
                   1990:   double brent(double ax, double bx, double cx, 
                   1991:               double (*f)(double), double tol, double *xmin); 
                   1992:   double f1dim(double x); 
                   1993:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1994:              double *fc, double (*func)(double)); 
                   1995:   int j; 
                   1996:   double xx,xmin,bx,ax; 
                   1997:   double fx,fb,fa;
1.187     brouard  1998: 
1.203     brouard  1999: #ifdef LINMINORIGINAL
                   2000: #else
                   2001:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2002: #endif
                   2003:   
1.126     brouard  2004:   ncom=n; 
                   2005:   pcom=vector(1,n); 
                   2006:   xicom=vector(1,n); 
                   2007:   nrfunc=func; 
                   2008:   for (j=1;j<=n;j++) { 
                   2009:     pcom[j]=p[j]; 
1.202     brouard  2010:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2011:   } 
1.187     brouard  2012: 
1.203     brouard  2013: #ifdef LINMINORIGINAL
                   2014:   xx=1.;
                   2015: #else
                   2016:   axs=0.0;
                   2017:   xxs=1.;
                   2018:   do{
                   2019:     xx= xxs;
                   2020: #endif
1.187     brouard  2021:     ax=0.;
                   2022:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2023:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2024:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2025:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2026:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2027:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2028:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2029: #ifdef LINMINORIGINAL
                   2030: #else
                   2031:     if (fx != fx){
1.224     brouard  2032:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2033:                        printf("|");
                   2034:                        fprintf(ficlog,"|");
1.203     brouard  2035: #ifdef DEBUGLINMIN
1.224     brouard  2036:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2037: #endif
                   2038:     }
1.224     brouard  2039:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2040: #endif
                   2041:   
1.191     brouard  2042: #ifdef DEBUGLINMIN
                   2043:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2044:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2045: #endif
1.224     brouard  2046: #ifdef LINMINORIGINAL
                   2047: #else
                   2048:        if(fb == fx){ /* Flat function in the direction */
                   2049:                xmin=xx;
                   2050:     *flat=1;
                   2051:        }else{
                   2052:     *flat=0;
                   2053: #endif
                   2054:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2055:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2056:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2057:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2058:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2059:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2060: #ifdef DEBUG
1.224     brouard  2061:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2062:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2063: #endif
                   2064: #ifdef LINMINORIGINAL
                   2065: #else
                   2066:                        }
1.126     brouard  2067: #endif
1.191     brouard  2068: #ifdef DEBUGLINMIN
                   2069:   printf("linmin end ");
1.202     brouard  2070:   fprintf(ficlog,"linmin end ");
1.191     brouard  2071: #endif
1.126     brouard  2072:   for (j=1;j<=n;j++) { 
1.203     brouard  2073: #ifdef LINMINORIGINAL
                   2074:     xi[j] *= xmin; 
                   2075: #else
                   2076: #ifdef DEBUGLINMIN
                   2077:     if(xxs <1.0)
                   2078:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2079: #endif
                   2080:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2081: #ifdef DEBUGLINMIN
                   2082:     if(xxs <1.0)
                   2083:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2084: #endif
                   2085: #endif
1.187     brouard  2086:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2087:   } 
1.191     brouard  2088: #ifdef DEBUGLINMIN
1.203     brouard  2089:   printf("\n");
1.191     brouard  2090:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2091:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2092:   for (j=1;j<=n;j++) { 
1.202     brouard  2093:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2094:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2095:     if(j % ncovmodel == 0){
1.191     brouard  2096:       printf("\n");
1.202     brouard  2097:       fprintf(ficlog,"\n");
                   2098:     }
1.191     brouard  2099:   }
1.203     brouard  2100: #else
1.191     brouard  2101: #endif
1.126     brouard  2102:   free_vector(xicom,1,n); 
                   2103:   free_vector(pcom,1,n); 
                   2104: } 
                   2105: 
                   2106: 
                   2107: /*************** powell ************************/
1.162     brouard  2108: /*
                   2109: Minimization of a function func of n variables. Input consists of an initial starting point
                   2110: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2111: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2112: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2113: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2114: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2115:  */
1.224     brouard  2116: #ifdef LINMINORIGINAL
                   2117: #else
                   2118:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2119:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2120: #endif
1.126     brouard  2121: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2122:            double (*func)(double [])) 
                   2123: { 
1.224     brouard  2124: #ifdef LINMINORIGINAL
                   2125:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2126:              double (*func)(double [])); 
1.224     brouard  2127: #else 
1.241     brouard  2128:  void linmin(double p[], double xi[], int n, double *fret,
                   2129:             double (*func)(double []),int *flat); 
1.224     brouard  2130: #endif
1.239     brouard  2131:  int i,ibig,j,jk,k; 
1.126     brouard  2132:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2133:   double directest;
1.126     brouard  2134:   double fp,fptt;
                   2135:   double *xits;
                   2136:   int niterf, itmp;
1.224     brouard  2137: #ifdef LINMINORIGINAL
                   2138: #else
                   2139: 
                   2140:   flatdir=ivector(1,n); 
                   2141:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2142: #endif
1.126     brouard  2143: 
                   2144:   pt=vector(1,n); 
                   2145:   ptt=vector(1,n); 
                   2146:   xit=vector(1,n); 
                   2147:   xits=vector(1,n); 
                   2148:   *fret=(*func)(p); 
                   2149:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2150:   rcurr_time = time(NULL);  
1.126     brouard  2151:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2152:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2153:     ibig=0; 
                   2154:     del=0.0; 
1.157     brouard  2155:     rlast_time=rcurr_time;
                   2156:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2157:     rcurr_time = time(NULL);  
                   2158:     curr_time = *localtime(&rcurr_time);
                   2159:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2160:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2161: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2162:     for (i=1;i<=n;i++) {
1.126     brouard  2163:       fprintf(ficrespow," %.12lf", p[i]);
                   2164:     }
1.239     brouard  2165:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2166:     printf("\n#model=  1      +     age ");
                   2167:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2168:     if(nagesqr==1){
1.241     brouard  2169:        printf("  + age*age  ");
                   2170:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2171:     }
                   2172:     for(j=1;j <=ncovmodel-2;j++){
                   2173:       if(Typevar[j]==0) {
                   2174:        printf("  +      V%d  ",Tvar[j]);
                   2175:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2176:       }else if(Typevar[j]==1) {
                   2177:        printf("  +    V%d*age ",Tvar[j]);
                   2178:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2179:       }else if(Typevar[j]==2) {
                   2180:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2181:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2182:       }
                   2183:     }
1.126     brouard  2184:     printf("\n");
1.239     brouard  2185: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2186: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2187:     fprintf(ficlog,"\n");
1.239     brouard  2188:     for(i=1,jk=1; i <=nlstate; i++){
                   2189:       for(k=1; k <=(nlstate+ndeath); k++){
                   2190:        if (k != i) {
                   2191:          printf("%d%d ",i,k);
                   2192:          fprintf(ficlog,"%d%d ",i,k);
                   2193:          for(j=1; j <=ncovmodel; j++){
                   2194:            printf("%12.7f ",p[jk]);
                   2195:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2196:            jk++; 
                   2197:          }
                   2198:          printf("\n");
                   2199:          fprintf(ficlog,"\n");
                   2200:        }
                   2201:       }
                   2202:     }
1.241     brouard  2203:     if(*iter <=3 && *iter >1){
1.157     brouard  2204:       tml = *localtime(&rcurr_time);
                   2205:       strcpy(strcurr,asctime(&tml));
                   2206:       rforecast_time=rcurr_time; 
1.126     brouard  2207:       itmp = strlen(strcurr);
                   2208:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2209:        strcurr[itmp-1]='\0';
1.162     brouard  2210:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2211:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2212:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2213:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2214:        forecast_time = *localtime(&rforecast_time);
                   2215:        strcpy(strfor,asctime(&forecast_time));
                   2216:        itmp = strlen(strfor);
                   2217:        if(strfor[itmp-1]=='\n')
                   2218:          strfor[itmp-1]='\0';
                   2219:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2220:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2221:       }
                   2222:     }
1.187     brouard  2223:     for (i=1;i<=n;i++) { /* For each direction i */
                   2224:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2225:       fptt=(*fret); 
                   2226: #ifdef DEBUG
1.203     brouard  2227:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2228:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2229: #endif
1.203     brouard  2230:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2231:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2232: #ifdef LINMINORIGINAL
1.188     brouard  2233:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2234: #else
                   2235:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2236:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2237: #endif
                   2238:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2239:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2240:                                /* because that direction will be replaced unless the gain del is small */
                   2241:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2242:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2243:                                /* with the new direction. */
                   2244:                                del=fabs(fptt-(*fret)); 
                   2245:                                ibig=i; 
1.126     brouard  2246:       } 
                   2247: #ifdef DEBUG
                   2248:       printf("%d %.12e",i,(*fret));
                   2249:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2250:       for (j=1;j<=n;j++) {
1.224     brouard  2251:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2252:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2253:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2254:       }
                   2255:       for(j=1;j<=n;j++) {
1.225     brouard  2256:                                printf(" p(%d)=%.12e",j,p[j]);
                   2257:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2258:       }
                   2259:       printf("\n");
                   2260:       fprintf(ficlog,"\n");
                   2261: #endif
1.187     brouard  2262:     } /* end loop on each direction i */
                   2263:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2264:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2265:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2266:       for(j=1;j<=n;j++) {
1.225     brouard  2267:                                if(flatdir[j] >0){
                   2268:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2269:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2270:                                }
                   2271:                                /* printf("\n"); */
                   2272:                                /* fprintf(ficlog,"\n"); */
                   2273:                        }
1.243     brouard  2274:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2275:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2276:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2277:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2278:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2279:       /* decreased of more than 3.84  */
                   2280:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2281:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2282:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2283:                        
1.188     brouard  2284:       /* Starting the program with initial values given by a former maximization will simply change */
                   2285:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2286:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2287:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2288: #ifdef DEBUG
                   2289:       int k[2],l;
                   2290:       k[0]=1;
                   2291:       k[1]=-1;
                   2292:       printf("Max: %.12e",(*func)(p));
                   2293:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2294:       for (j=1;j<=n;j++) {
                   2295:        printf(" %.12e",p[j]);
                   2296:        fprintf(ficlog," %.12e",p[j]);
                   2297:       }
                   2298:       printf("\n");
                   2299:       fprintf(ficlog,"\n");
                   2300:       for(l=0;l<=1;l++) {
                   2301:        for (j=1;j<=n;j++) {
                   2302:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2303:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2304:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2305:        }
                   2306:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2307:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2308:       }
                   2309: #endif
                   2310: 
1.224     brouard  2311: #ifdef LINMINORIGINAL
                   2312: #else
                   2313:       free_ivector(flatdir,1,n); 
                   2314: #endif
1.126     brouard  2315:       free_vector(xit,1,n); 
                   2316:       free_vector(xits,1,n); 
                   2317:       free_vector(ptt,1,n); 
                   2318:       free_vector(pt,1,n); 
                   2319:       return; 
1.192     brouard  2320:     } /* enough precision */ 
1.240     brouard  2321:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2322:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2323:       ptt[j]=2.0*p[j]-pt[j]; 
                   2324:       xit[j]=p[j]-pt[j]; 
                   2325:       pt[j]=p[j]; 
                   2326:     } 
1.181     brouard  2327:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2328: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2329:                if (*iter <=4) {
1.225     brouard  2330: #else
                   2331: #endif
1.224     brouard  2332: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2333: #else
1.161     brouard  2334:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2335: #endif
1.162     brouard  2336:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2337:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2338:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2339:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2340:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2341:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2342:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2343:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2344:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2345:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2346:       /* mu² and del² are equal when f3=f1 */
                   2347:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2348:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2349:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2350:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2351: #ifdef NRCORIGINAL
                   2352:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2353: #else
                   2354:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2355:       t= t- del*SQR(fp-fptt);
1.183     brouard  2356: #endif
1.202     brouard  2357:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2358: #ifdef DEBUG
1.181     brouard  2359:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2360:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2361:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2362:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2363:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2364:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2365:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2366:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2367: #endif
1.183     brouard  2368: #ifdef POWELLORIGINAL
                   2369:       if (t < 0.0) { /* Then we use it for new direction */
                   2370: #else
1.182     brouard  2371:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2372:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2373:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2374:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2375:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2376:       } 
1.181     brouard  2377:       if (directest < 0.0) { /* Then we use it for new direction */
                   2378: #endif
1.191     brouard  2379: #ifdef DEBUGLINMIN
1.234     brouard  2380:        printf("Before linmin in direction P%d-P0\n",n);
                   2381:        for (j=1;j<=n;j++) {
                   2382:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2383:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2384:          if(j % ncovmodel == 0){
                   2385:            printf("\n");
                   2386:            fprintf(ficlog,"\n");
                   2387:          }
                   2388:        }
1.224     brouard  2389: #endif
                   2390: #ifdef LINMINORIGINAL
1.234     brouard  2391:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2392: #else
1.234     brouard  2393:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2394:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2395: #endif
1.234     brouard  2396:        
1.191     brouard  2397: #ifdef DEBUGLINMIN
1.234     brouard  2398:        for (j=1;j<=n;j++) { 
                   2399:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2400:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2401:          if(j % ncovmodel == 0){
                   2402:            printf("\n");
                   2403:            fprintf(ficlog,"\n");
                   2404:          }
                   2405:        }
1.224     brouard  2406: #endif
1.234     brouard  2407:        for (j=1;j<=n;j++) { 
                   2408:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2409:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2410:        }
1.224     brouard  2411: #ifdef LINMINORIGINAL
                   2412: #else
1.234     brouard  2413:        for (j=1, flatd=0;j<=n;j++) {
                   2414:          if(flatdir[j]>0)
                   2415:            flatd++;
                   2416:        }
                   2417:        if(flatd >0){
1.255     brouard  2418:          printf("%d flat directions: ",flatd);
                   2419:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2420:          for (j=1;j<=n;j++) { 
                   2421:            if(flatdir[j]>0){
                   2422:              printf("%d ",j);
                   2423:              fprintf(ficlog,"%d ",j);
                   2424:            }
                   2425:          }
                   2426:          printf("\n");
                   2427:          fprintf(ficlog,"\n");
                   2428:        }
1.191     brouard  2429: #endif
1.234     brouard  2430:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2431:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2432:        
1.126     brouard  2433: #ifdef DEBUG
1.234     brouard  2434:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2435:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2436:        for(j=1;j<=n;j++){
                   2437:          printf(" %lf",xit[j]);
                   2438:          fprintf(ficlog," %lf",xit[j]);
                   2439:        }
                   2440:        printf("\n");
                   2441:        fprintf(ficlog,"\n");
1.126     brouard  2442: #endif
1.192     brouard  2443:       } /* end of t or directest negative */
1.224     brouard  2444: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2445: #else
1.234     brouard  2446:       } /* end if (fptt < fp)  */
1.192     brouard  2447: #endif
1.225     brouard  2448: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2449:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2450: #else
1.224     brouard  2451: #endif
1.234     brouard  2452:                } /* loop iteration */ 
1.126     brouard  2453: } 
1.234     brouard  2454:   
1.126     brouard  2455: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2456:   
1.235     brouard  2457:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2458:   {
1.235     brouard  2459:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2460:        (and selected quantitative values in nres)
                   2461:        by left multiplying the unit
1.234     brouard  2462:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2463:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2464:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2465:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2466:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2467:   /* Initial matrix pimij */
                   2468:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2469:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2470:   /*  0,                   0                  , 1} */
                   2471:   /*
                   2472:    * and after some iteration: */
                   2473:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2474:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2475:   /*  0,                   0                  , 1} */
                   2476:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2477:   /* {0.51571254859325999, 0.4842874514067399, */
                   2478:   /*  0.51326036147820708, 0.48673963852179264} */
                   2479:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2480:     
1.126     brouard  2481:   int i, ii,j,k;
1.209     brouard  2482:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2483:   /* double **matprod2(); */ /* test */
1.218     brouard  2484:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2485:   double **newm;
1.209     brouard  2486:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2487:   int ncvloop=0;
1.169     brouard  2488:   
1.209     brouard  2489:   min=vector(1,nlstate);
                   2490:   max=vector(1,nlstate);
                   2491:   meandiff=vector(1,nlstate);
                   2492: 
1.218     brouard  2493:        /* Starting with matrix unity */
1.126     brouard  2494:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2495:     for (j=1;j<=nlstate+ndeath;j++){
                   2496:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2497:     }
1.169     brouard  2498:   
                   2499:   cov[1]=1.;
                   2500:   
                   2501:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2502:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2503:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2504:     ncvloop++;
1.126     brouard  2505:     newm=savm;
                   2506:     /* Covariates have to be included here again */
1.138     brouard  2507:     cov[2]=agefin;
1.187     brouard  2508:     if(nagesqr==1)
                   2509:       cov[3]= agefin*agefin;;
1.234     brouard  2510:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2511:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2512:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2513:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2514:     }
                   2515:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2516:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2517:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2518:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2519:     }
1.237     brouard  2520:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2521:       if(Dummy[Tvar[Tage[k]]]){
                   2522:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2523:       } else{
1.235     brouard  2524:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2525:       }
1.235     brouard  2526:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2527:     }
1.237     brouard  2528:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2529:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2530:       if(Dummy[Tvard[k][1]==0]){
                   2531:        if(Dummy[Tvard[k][2]==0]){
                   2532:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2533:        }else{
                   2534:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2535:        }
                   2536:       }else{
                   2537:        if(Dummy[Tvard[k][2]==0]){
                   2538:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2539:        }else{
                   2540:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2541:        }
                   2542:       }
1.234     brouard  2543:     }
1.138     brouard  2544:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2545:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2546:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2547:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2548:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2549:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2550:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2551:     
1.126     brouard  2552:     savm=oldm;
                   2553:     oldm=newm;
1.209     brouard  2554: 
                   2555:     for(j=1; j<=nlstate; j++){
                   2556:       max[j]=0.;
                   2557:       min[j]=1.;
                   2558:     }
                   2559:     for(i=1;i<=nlstate;i++){
                   2560:       sumnew=0;
                   2561:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2562:       for(j=1; j<=nlstate; j++){ 
                   2563:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2564:        max[j]=FMAX(max[j],prlim[i][j]);
                   2565:        min[j]=FMIN(min[j],prlim[i][j]);
                   2566:       }
                   2567:     }
                   2568: 
1.126     brouard  2569:     maxmax=0.;
1.209     brouard  2570:     for(j=1; j<=nlstate; j++){
                   2571:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2572:       maxmax=FMAX(maxmax,meandiff[j]);
                   2573:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2574:     } /* j loop */
1.203     brouard  2575:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2576:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2577:     if(maxmax < ftolpl){
1.209     brouard  2578:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2579:       free_vector(min,1,nlstate);
                   2580:       free_vector(max,1,nlstate);
                   2581:       free_vector(meandiff,1,nlstate);
1.126     brouard  2582:       return prlim;
                   2583:     }
1.169     brouard  2584:   } /* age loop */
1.208     brouard  2585:     /* After some age loop it doesn't converge */
1.209     brouard  2586:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2587: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2588:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2589:   free_vector(min,1,nlstate);
                   2590:   free_vector(max,1,nlstate);
                   2591:   free_vector(meandiff,1,nlstate);
1.208     brouard  2592:   
1.169     brouard  2593:   return prlim; /* should not reach here */
1.126     brouard  2594: }
                   2595: 
1.217     brouard  2596: 
                   2597:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2598: 
1.218     brouard  2599:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2600:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2601:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2602: {
1.218     brouard  2603:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2604:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2605:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2606:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2607:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2608:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2609:   /* Initial matrix pimij */
                   2610:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2611:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2612:   /*  0,                   0                  , 1} */
                   2613:   /*
                   2614:    * and after some iteration: */
                   2615:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2616:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2617:   /*  0,                   0                  , 1} */
                   2618:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2619:   /* {0.51571254859325999, 0.4842874514067399, */
                   2620:   /*  0.51326036147820708, 0.48673963852179264} */
                   2621:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2622: 
                   2623:   int i, ii,j,k;
1.247     brouard  2624:   int first=0;
1.217     brouard  2625:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2626:   /* double **matprod2(); */ /* test */
                   2627:   double **out, cov[NCOVMAX+1], **bmij();
                   2628:   double **newm;
1.218     brouard  2629:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2630:   double        **oldm, **savm;  /* for use */
                   2631: 
1.217     brouard  2632:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2633:   int ncvloop=0;
                   2634:   
                   2635:   min=vector(1,nlstate);
                   2636:   max=vector(1,nlstate);
                   2637:   meandiff=vector(1,nlstate);
                   2638: 
1.218     brouard  2639:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2640:        oldm=oldms; savm=savms;
                   2641: 
                   2642:        /* Starting with matrix unity */
                   2643:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2644:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2645:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2646:     }
                   2647:   
                   2648:   cov[1]=1.;
                   2649:   
                   2650:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2651:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2652:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2653:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2654:     ncvloop++;
1.218     brouard  2655:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2656:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2657:     /* Covariates have to be included here again */
                   2658:     cov[2]=agefin;
                   2659:     if(nagesqr==1)
                   2660:       cov[3]= agefin*agefin;;
1.242     brouard  2661:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2662:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2663:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2664:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2665:     }
                   2666:     /* for (k=1; k<=cptcovn;k++) { */
                   2667:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2668:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2669:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2670:     /* } */
                   2671:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2672:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2673:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2674:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2675:     }
                   2676:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2677:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2678:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2679:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2680:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2681:       if(Dummy[Tvar[Tage[k]]]){
                   2682:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2683:       } else{
                   2684:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2685:       }
                   2686:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2687:     }
                   2688:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2689:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2690:       if(Dummy[Tvard[k][1]==0]){
                   2691:        if(Dummy[Tvard[k][2]==0]){
                   2692:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2693:        }else{
                   2694:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2695:        }
                   2696:       }else{
                   2697:        if(Dummy[Tvard[k][2]==0]){
                   2698:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2699:        }else{
                   2700:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2701:        }
                   2702:       }
1.217     brouard  2703:     }
                   2704:     
                   2705:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2706:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2707:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2708:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2709:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2710:                /* ij should be linked to the correct index of cov */
                   2711:                /* age and covariate values ij are in 'cov', but we need to pass
                   2712:                 * ij for the observed prevalence at age and status and covariate
                   2713:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2714:                 */
                   2715:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2716:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2717:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2718:     savm=oldm;
                   2719:     oldm=newm;
                   2720:     for(j=1; j<=nlstate; j++){
                   2721:       max[j]=0.;
                   2722:       min[j]=1.;
                   2723:     }
                   2724:     for(j=1; j<=nlstate; j++){ 
                   2725:       for(i=1;i<=nlstate;i++){
1.234     brouard  2726:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2727:        bprlim[i][j]= newm[i][j];
                   2728:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2729:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2730:       }
                   2731:     }
1.218     brouard  2732:                
1.217     brouard  2733:     maxmax=0.;
                   2734:     for(i=1; i<=nlstate; i++){
                   2735:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2736:       maxmax=FMAX(maxmax,meandiff[i]);
                   2737:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2738:     } /* j loop */
                   2739:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2740:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2741:     if(maxmax < ftolpl){
1.220     brouard  2742:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2743:       free_vector(min,1,nlstate);
                   2744:       free_vector(max,1,nlstate);
                   2745:       free_vector(meandiff,1,nlstate);
                   2746:       return bprlim;
                   2747:     }
                   2748:   } /* age loop */
                   2749:     /* After some age loop it doesn't converge */
1.247     brouard  2750:   if(first){
                   2751:     first=1;
                   2752:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2753: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2754:   }
                   2755:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2756: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2757:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2758:   free_vector(min,1,nlstate);
                   2759:   free_vector(max,1,nlstate);
                   2760:   free_vector(meandiff,1,nlstate);
                   2761:   
                   2762:   return bprlim; /* should not reach here */
                   2763: }
                   2764: 
1.126     brouard  2765: /*************** transition probabilities ***************/ 
                   2766: 
                   2767: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2768: {
1.138     brouard  2769:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2770:      computes the probability to be observed in state j being in state i by appying the
                   2771:      model to the ncovmodel covariates (including constant and age).
                   2772:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2773:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2774:      ncth covariate in the global vector x is given by the formula:
                   2775:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2776:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2777:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2778:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2779:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2780:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2781:   */
                   2782:   double s1, lnpijopii;
1.126     brouard  2783:   /*double t34;*/
1.164     brouard  2784:   int i,j, nc, ii, jj;
1.126     brouard  2785: 
1.223     brouard  2786:   for(i=1; i<= nlstate; i++){
                   2787:     for(j=1; j<i;j++){
                   2788:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2789:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2790:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2791:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2792:       }
                   2793:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2794:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2795:     }
                   2796:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2797:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2798:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2799:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2800:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2801:       }
                   2802:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2803:     }
                   2804:   }
1.218     brouard  2805:   
1.223     brouard  2806:   for(i=1; i<= nlstate; i++){
                   2807:     s1=0;
                   2808:     for(j=1; j<i; j++){
                   2809:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2810:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2811:     }
                   2812:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2813:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2814:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2815:     }
                   2816:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2817:     ps[i][i]=1./(s1+1.);
                   2818:     /* Computing other pijs */
                   2819:     for(j=1; j<i; j++)
                   2820:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2821:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2822:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2823:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2824:   } /* end i */
1.218     brouard  2825:   
1.223     brouard  2826:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2827:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2828:       ps[ii][jj]=0;
                   2829:       ps[ii][ii]=1;
                   2830:     }
                   2831:   }
1.218     brouard  2832:   
                   2833:   
1.223     brouard  2834:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2835:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2836:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2837:   /*   } */
                   2838:   /*   printf("\n "); */
                   2839:   /* } */
                   2840:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2841:   /*
                   2842:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2843:                goto end;*/
1.223     brouard  2844:   return ps;
1.126     brouard  2845: }
                   2846: 
1.218     brouard  2847: /*************** backward transition probabilities ***************/ 
                   2848: 
                   2849:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2850: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2851:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2852: {
1.222     brouard  2853:   /* Computes the backward probability at age agefin and covariate ij
                   2854:    * and returns in **ps as well as **bmij.
                   2855:    */
1.218     brouard  2856:   int i, ii, j,k;
1.222     brouard  2857:   
                   2858:   double **out, **pmij();
                   2859:   double sumnew=0.;
1.218     brouard  2860:   double agefin;
1.222     brouard  2861:   
                   2862:   double **dnewm, **dsavm, **doldm;
                   2863:   double **bbmij;
                   2864:   
1.218     brouard  2865:   doldm=ddoldms; /* global pointers */
1.222     brouard  2866:   dnewm=ddnewms;
                   2867:   dsavm=ddsavms;
                   2868:   
                   2869:   agefin=cov[2];
                   2870:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2871:      the observed prevalence (with this covariate ij) */
                   2872:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2873:   /* We do have the matrix Px in savm  and we need pij */
                   2874:   for (j=1;j<=nlstate+ndeath;j++){
                   2875:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2876:     for (ii=1;ii<=nlstate;ii++){
                   2877:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2878:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2879:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2880:       if(sumnew >= 1.e-10){
                   2881:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2882:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2883:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2884:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2885:        /* }else */
                   2886:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2887:       }else{
1.242     brouard  2888:        ;
                   2889:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2890:       }
                   2891:     } /*End ii */
                   2892:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2893:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2894:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2895:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2896:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2897:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2898:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2899:   for (j=1;j<=nlstate+ndeath;j++){
                   2900:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2901:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2902:     }
                   2903:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2904:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2905:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2906:   /* end bmij */
                   2907:   return ps; 
1.218     brouard  2908: }
1.217     brouard  2909: /*************** transition probabilities ***************/ 
                   2910: 
1.218     brouard  2911: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2912: {
                   2913:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2914:      computes the probability to be observed in state j being in state i by appying the
                   2915:      model to the ncovmodel covariates (including constant and age).
                   2916:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2917:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2918:      ncth covariate in the global vector x is given by the formula:
                   2919:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2920:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2921:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2922:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2923:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2924:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2925:   */
                   2926:   double s1, lnpijopii;
                   2927:   /*double t34;*/
                   2928:   int i,j, nc, ii, jj;
                   2929: 
1.234     brouard  2930:   for(i=1; i<= nlstate; i++){
                   2931:     for(j=1; j<i;j++){
                   2932:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2933:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2934:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2935:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2936:       }
                   2937:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2938:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2939:     }
                   2940:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2941:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2942:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2943:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2944:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2945:       }
                   2946:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2947:     }
                   2948:   }
                   2949:   
                   2950:   for(i=1; i<= nlstate; i++){
                   2951:     s1=0;
                   2952:     for(j=1; j<i; j++){
                   2953:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2954:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2955:     }
                   2956:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2957:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2958:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2959:     }
                   2960:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2961:     ps[i][i]=1./(s1+1.);
                   2962:     /* Computing other pijs */
                   2963:     for(j=1; j<i; j++)
                   2964:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2965:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2966:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2967:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2968:   } /* end i */
                   2969:   
                   2970:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2971:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2972:       ps[ii][jj]=0;
                   2973:       ps[ii][ii]=1;
                   2974:     }
                   2975:   }
                   2976:   /* Added for backcast */ /* Transposed matrix too */
                   2977:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2978:     s1=0.;
                   2979:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2980:       s1+=ps[ii][jj];
                   2981:     }
                   2982:     for(ii=1; ii<= nlstate; ii++){
                   2983:       ps[ii][jj]=ps[ii][jj]/s1;
                   2984:     }
                   2985:   }
                   2986:   /* Transposition */
                   2987:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2988:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2989:       s1=ps[ii][jj];
                   2990:       ps[ii][jj]=ps[jj][ii];
                   2991:       ps[jj][ii]=s1;
                   2992:     }
                   2993:   }
                   2994:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2995:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2996:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2997:   /*   } */
                   2998:   /*   printf("\n "); */
                   2999:   /* } */
                   3000:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3001:   /*
                   3002:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3003:     goto end;*/
                   3004:   return ps;
1.217     brouard  3005: }
                   3006: 
                   3007: 
1.126     brouard  3008: /**************** Product of 2 matrices ******************/
                   3009: 
1.145     brouard  3010: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3011: {
                   3012:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3013:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3014:   /* in, b, out are matrice of pointers which should have been initialized 
                   3015:      before: only the contents of out is modified. The function returns
                   3016:      a pointer to pointers identical to out */
1.145     brouard  3017:   int i, j, k;
1.126     brouard  3018:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3019:     for(k=ncolol; k<=ncoloh; k++){
                   3020:       out[i][k]=0.;
                   3021:       for(j=ncl; j<=nch; j++)
                   3022:        out[i][k] +=in[i][j]*b[j][k];
                   3023:     }
1.126     brouard  3024:   return out;
                   3025: }
                   3026: 
                   3027: 
                   3028: /************* Higher Matrix Product ***************/
                   3029: 
1.235     brouard  3030: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3031: {
1.218     brouard  3032:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3033:      'nhstepm*hstepm*stepm' months (i.e. until
                   3034:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3035:      nhstepm*hstepm matrices. 
                   3036:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3037:      (typically every 2 years instead of every month which is too big 
                   3038:      for the memory).
                   3039:      Model is determined by parameters x and covariates have to be 
                   3040:      included manually here. 
                   3041: 
                   3042:      */
                   3043: 
                   3044:   int i, j, d, h, k;
1.131     brouard  3045:   double **out, cov[NCOVMAX+1];
1.126     brouard  3046:   double **newm;
1.187     brouard  3047:   double agexact;
1.214     brouard  3048:   double agebegin, ageend;
1.126     brouard  3049: 
                   3050:   /* Hstepm could be zero and should return the unit matrix */
                   3051:   for (i=1;i<=nlstate+ndeath;i++)
                   3052:     for (j=1;j<=nlstate+ndeath;j++){
                   3053:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3054:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3055:     }
                   3056:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3057:   for(h=1; h <=nhstepm; h++){
                   3058:     for(d=1; d <=hstepm; d++){
                   3059:       newm=savm;
                   3060:       /* Covariates have to be included here again */
                   3061:       cov[1]=1.;
1.214     brouard  3062:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3063:       cov[2]=agexact;
                   3064:       if(nagesqr==1)
1.227     brouard  3065:        cov[3]= agexact*agexact;
1.235     brouard  3066:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3067:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3068:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3069:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3070:       }
                   3071:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3072:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3073:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3074:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3075:       }
                   3076:       for (k=1; k<=cptcovage;k++){
                   3077:        if(Dummy[Tvar[Tage[k]]]){
                   3078:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3079:        } else{
                   3080:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3081:        }
                   3082:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3083:       }
                   3084:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3085:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3086:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3087:       }
                   3088:       /* for (k=1; k<=cptcovn;k++)  */
                   3089:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3090:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3091:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3092:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3093:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3094:       
                   3095:       
1.126     brouard  3096:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3097:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3098:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3099:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3100:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3101:       /* if((int)age == 70){ */
                   3102:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3103:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3104:       /*         printf("%d pmmij ",i); */
                   3105:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3106:       /*           printf("%f ",pmmij[i][j]); */
                   3107:       /*         } */
                   3108:       /*         printf(" oldm "); */
                   3109:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3110:       /*           printf("%f ",oldm[i][j]); */
                   3111:       /*         } */
                   3112:       /*         printf("\n"); */
                   3113:       /*       } */
                   3114:       /* } */
1.126     brouard  3115:       savm=oldm;
                   3116:       oldm=newm;
                   3117:     }
                   3118:     for(i=1; i<=nlstate+ndeath; i++)
                   3119:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3120:                                po[i][j][h]=newm[i][j];
                   3121:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3122:       }
1.128     brouard  3123:     /*printf("h=%d ",h);*/
1.126     brouard  3124:   } /* end h */
1.218     brouard  3125:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3126:   return po;
                   3127: }
                   3128: 
1.217     brouard  3129: /************* Higher Back Matrix Product ***************/
1.218     brouard  3130: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3131: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3132: {
1.218     brouard  3133:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3134:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3135:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3136:      nhstepm*hstepm matrices.
                   3137:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3138:      (typically every 2 years instead of every month which is too big
1.217     brouard  3139:      for the memory).
1.218     brouard  3140:      Model is determined by parameters x and covariates have to be
                   3141:      included manually here.
1.217     brouard  3142: 
1.222     brouard  3143:   */
1.217     brouard  3144: 
                   3145:   int i, j, d, h, k;
                   3146:   double **out, cov[NCOVMAX+1];
                   3147:   double **newm;
                   3148:   double agexact;
                   3149:   double agebegin, ageend;
1.222     brouard  3150:   double **oldm, **savm;
1.217     brouard  3151: 
1.222     brouard  3152:   oldm=oldms;savm=savms;
1.217     brouard  3153:   /* Hstepm could be zero and should return the unit matrix */
                   3154:   for (i=1;i<=nlstate+ndeath;i++)
                   3155:     for (j=1;j<=nlstate+ndeath;j++){
                   3156:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3157:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3158:     }
                   3159:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3160:   for(h=1; h <=nhstepm; h++){
                   3161:     for(d=1; d <=hstepm; d++){
                   3162:       newm=savm;
                   3163:       /* Covariates have to be included here again */
                   3164:       cov[1]=1.;
                   3165:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3166:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3167:       cov[2]=agexact;
                   3168:       if(nagesqr==1)
1.222     brouard  3169:        cov[3]= agexact*agexact;
1.218     brouard  3170:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3171:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3172:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3173:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3174:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3175:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3176:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3177:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3178:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3179:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3180:                        
                   3181:                        
1.217     brouard  3182:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3183:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3184:       /* Careful transposed matrix */
1.222     brouard  3185:       /* age is in cov[2] */
1.218     brouard  3186:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3187:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3188:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3189:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3190:       /* if((int)age == 70){ */
                   3191:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3192:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3193:       /*         printf("%d pmmij ",i); */
                   3194:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3195:       /*           printf("%f ",pmmij[i][j]); */
                   3196:       /*         } */
                   3197:       /*         printf(" oldm "); */
                   3198:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3199:       /*           printf("%f ",oldm[i][j]); */
                   3200:       /*         } */
                   3201:       /*         printf("\n"); */
                   3202:       /*       } */
                   3203:       /* } */
                   3204:       savm=oldm;
                   3205:       oldm=newm;
                   3206:     }
                   3207:     for(i=1; i<=nlstate+ndeath; i++)
                   3208:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3209:        po[i][j][h]=newm[i][j];
                   3210:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3211:       }
                   3212:     /*printf("h=%d ",h);*/
                   3213:   } /* end h */
1.222     brouard  3214:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3215:   return po;
                   3216: }
                   3217: 
                   3218: 
1.162     brouard  3219: #ifdef NLOPT
                   3220:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3221:   double fret;
                   3222:   double *xt;
                   3223:   int j;
                   3224:   myfunc_data *d2 = (myfunc_data *) pd;
                   3225: /* xt = (p1-1); */
                   3226:   xt=vector(1,n); 
                   3227:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3228: 
                   3229:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3230:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3231:   printf("Function = %.12lf ",fret);
                   3232:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3233:   printf("\n");
                   3234:  free_vector(xt,1,n);
                   3235:   return fret;
                   3236: }
                   3237: #endif
1.126     brouard  3238: 
                   3239: /*************** log-likelihood *************/
                   3240: double func( double *x)
                   3241: {
1.226     brouard  3242:   int i, ii, j, k, mi, d, kk;
                   3243:   int ioffset=0;
                   3244:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3245:   double **out;
                   3246:   double lli; /* Individual log likelihood */
                   3247:   int s1, s2;
1.228     brouard  3248:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3249:   double bbh, survp;
                   3250:   long ipmx;
                   3251:   double agexact;
                   3252:   /*extern weight */
                   3253:   /* We are differentiating ll according to initial status */
                   3254:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3255:   /*for(i=1;i<imx;i++) 
                   3256:     printf(" %d\n",s[4][i]);
                   3257:   */
1.162     brouard  3258: 
1.226     brouard  3259:   ++countcallfunc;
1.162     brouard  3260: 
1.226     brouard  3261:   cov[1]=1.;
1.126     brouard  3262: 
1.226     brouard  3263:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3264:   ioffset=0;
1.226     brouard  3265:   if(mle==1){
                   3266:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3267:       /* Computes the values of the ncovmodel covariates of the model
                   3268:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3269:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3270:         to be observed in j being in i according to the model.
                   3271:       */
1.243     brouard  3272:       ioffset=2+nagesqr ;
1.233     brouard  3273:    /* Fixed */
1.234     brouard  3274:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3275:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3276:       }
1.226     brouard  3277:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3278:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3279:         has been calculated etc */
                   3280:       /* For an individual i, wav[i] gives the number of effective waves */
                   3281:       /* We compute the contribution to Likelihood of each effective transition
                   3282:         mw[mi][i] is real wave of the mi th effectve wave */
                   3283:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3284:         s2=s[mw[mi+1][i]][i];
                   3285:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3286:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3287:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3288:       */
                   3289:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3290:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3291:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3292:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3293:        }
                   3294:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3295:          for (j=1;j<=nlstate+ndeath;j++){
                   3296:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3297:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3298:          }
                   3299:        for(d=0; d<dh[mi][i]; d++){
                   3300:          newm=savm;
                   3301:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3302:          cov[2]=agexact;
                   3303:          if(nagesqr==1)
                   3304:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3305:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3306:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3307:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3308:          else
                   3309:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3310:          }
                   3311:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3312:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3313:          savm=oldm;
                   3314:          oldm=newm;
                   3315:        } /* end mult */
                   3316:        
                   3317:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3318:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3319:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3320:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3321:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3322:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3323:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3324:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3325:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3326:                                 * -stepm/2 to stepm/2 .
                   3327:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3328:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3329:                                 */
1.234     brouard  3330:        s1=s[mw[mi][i]][i];
                   3331:        s2=s[mw[mi+1][i]][i];
                   3332:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3333:        /* bias bh is positive if real duration
                   3334:         * is higher than the multiple of stepm and negative otherwise.
                   3335:         */
                   3336:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3337:        if( s2 > nlstate){ 
                   3338:          /* i.e. if s2 is a death state and if the date of death is known 
                   3339:             then the contribution to the likelihood is the probability to 
                   3340:             die between last step unit time and current  step unit time, 
                   3341:             which is also equal to probability to die before dh 
                   3342:             minus probability to die before dh-stepm . 
                   3343:             In version up to 0.92 likelihood was computed
                   3344:             as if date of death was unknown. Death was treated as any other
                   3345:             health state: the date of the interview describes the actual state
                   3346:             and not the date of a change in health state. The former idea was
                   3347:             to consider that at each interview the state was recorded
                   3348:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3349:             introduced the exact date of death then we should have modified
                   3350:             the contribution of an exact death to the likelihood. This new
                   3351:             contribution is smaller and very dependent of the step unit
                   3352:             stepm. It is no more the probability to die between last interview
                   3353:             and month of death but the probability to survive from last
                   3354:             interview up to one month before death multiplied by the
                   3355:             probability to die within a month. Thanks to Chris
                   3356:             Jackson for correcting this bug.  Former versions increased
                   3357:             mortality artificially. The bad side is that we add another loop
                   3358:             which slows down the processing. The difference can be up to 10%
                   3359:             lower mortality.
                   3360:          */
                   3361:          /* If, at the beginning of the maximization mostly, the
                   3362:             cumulative probability or probability to be dead is
                   3363:             constant (ie = 1) over time d, the difference is equal to
                   3364:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3365:             s1 at precedent wave, to be dead a month before current
                   3366:             wave is equal to probability, being at state s1 at
                   3367:             precedent wave, to be dead at mont of the current
                   3368:             wave. Then the observed probability (that this person died)
                   3369:             is null according to current estimated parameter. In fact,
                   3370:             it should be very low but not zero otherwise the log go to
                   3371:             infinity.
                   3372:          */
1.183     brouard  3373: /* #ifdef INFINITYORIGINAL */
                   3374: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3375: /* #else */
                   3376: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3377: /*         lli=log(mytinydouble); */
                   3378: /*       else */
                   3379: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3380: /* #endif */
1.226     brouard  3381:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3382:          
1.226     brouard  3383:        } else if  ( s2==-1 ) { /* alive */
                   3384:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3385:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3386:          /*survp += out[s1][j]; */
                   3387:          lli= log(survp);
                   3388:        }
                   3389:        else if  (s2==-4) { 
                   3390:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3391:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3392:          lli= log(survp); 
                   3393:        } 
                   3394:        else if  (s2==-5) { 
                   3395:          for (j=1,survp=0. ; j<=2; j++)  
                   3396:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3397:          lli= log(survp); 
                   3398:        } 
                   3399:        else{
                   3400:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3401:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3402:        } 
                   3403:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3404:        /*if(lli ==000.0)*/
                   3405:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3406:        ipmx +=1;
                   3407:        sw += weight[i];
                   3408:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3409:        /* if (lli < log(mytinydouble)){ */
                   3410:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3411:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3412:        /* } */
                   3413:       } /* end of wave */
                   3414:     } /* end of individual */
                   3415:   }  else if(mle==2){
                   3416:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3417:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3418:       for(mi=1; mi<= wav[i]-1; mi++){
                   3419:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3420:          for (j=1;j<=nlstate+ndeath;j++){
                   3421:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3422:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3423:          }
                   3424:        for(d=0; d<=dh[mi][i]; d++){
                   3425:          newm=savm;
                   3426:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3427:          cov[2]=agexact;
                   3428:          if(nagesqr==1)
                   3429:            cov[3]= agexact*agexact;
                   3430:          for (kk=1; kk<=cptcovage;kk++) {
                   3431:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3432:          }
                   3433:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3434:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3435:          savm=oldm;
                   3436:          oldm=newm;
                   3437:        } /* end mult */
                   3438:       
                   3439:        s1=s[mw[mi][i]][i];
                   3440:        s2=s[mw[mi+1][i]][i];
                   3441:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3442:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3443:        ipmx +=1;
                   3444:        sw += weight[i];
                   3445:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3446:       } /* end of wave */
                   3447:     } /* end of individual */
                   3448:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3449:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3450:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3451:       for(mi=1; mi<= wav[i]-1; mi++){
                   3452:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3453:          for (j=1;j<=nlstate+ndeath;j++){
                   3454:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3455:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3456:          }
                   3457:        for(d=0; d<dh[mi][i]; d++){
                   3458:          newm=savm;
                   3459:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3460:          cov[2]=agexact;
                   3461:          if(nagesqr==1)
                   3462:            cov[3]= agexact*agexact;
                   3463:          for (kk=1; kk<=cptcovage;kk++) {
                   3464:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3465:          }
                   3466:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3467:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3468:          savm=oldm;
                   3469:          oldm=newm;
                   3470:        } /* end mult */
                   3471:       
                   3472:        s1=s[mw[mi][i]][i];
                   3473:        s2=s[mw[mi+1][i]][i];
                   3474:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3475:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3476:        ipmx +=1;
                   3477:        sw += weight[i];
                   3478:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3479:       } /* end of wave */
                   3480:     } /* end of individual */
                   3481:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3482:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3483:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3484:       for(mi=1; mi<= wav[i]-1; mi++){
                   3485:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3486:          for (j=1;j<=nlstate+ndeath;j++){
                   3487:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3488:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3489:          }
                   3490:        for(d=0; d<dh[mi][i]; d++){
                   3491:          newm=savm;
                   3492:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3493:          cov[2]=agexact;
                   3494:          if(nagesqr==1)
                   3495:            cov[3]= agexact*agexact;
                   3496:          for (kk=1; kk<=cptcovage;kk++) {
                   3497:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3498:          }
1.126     brouard  3499:        
1.226     brouard  3500:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3501:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3502:          savm=oldm;
                   3503:          oldm=newm;
                   3504:        } /* end mult */
                   3505:       
                   3506:        s1=s[mw[mi][i]][i];
                   3507:        s2=s[mw[mi+1][i]][i];
                   3508:        if( s2 > nlstate){ 
                   3509:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3510:        } else if  ( s2==-1 ) { /* alive */
                   3511:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3512:            survp += out[s1][j];
                   3513:          lli= log(survp);
                   3514:        }else{
                   3515:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3516:        }
                   3517:        ipmx +=1;
                   3518:        sw += weight[i];
                   3519:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3520: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3521:       } /* end of wave */
                   3522:     } /* end of individual */
                   3523:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3524:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3525:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3526:       for(mi=1; mi<= wav[i]-1; mi++){
                   3527:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3528:          for (j=1;j<=nlstate+ndeath;j++){
                   3529:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3530:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3531:          }
                   3532:        for(d=0; d<dh[mi][i]; d++){
                   3533:          newm=savm;
                   3534:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3535:          cov[2]=agexact;
                   3536:          if(nagesqr==1)
                   3537:            cov[3]= agexact*agexact;
                   3538:          for (kk=1; kk<=cptcovage;kk++) {
                   3539:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3540:          }
1.126     brouard  3541:        
1.226     brouard  3542:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3543:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3544:          savm=oldm;
                   3545:          oldm=newm;
                   3546:        } /* end mult */
                   3547:       
                   3548:        s1=s[mw[mi][i]][i];
                   3549:        s2=s[mw[mi+1][i]][i];
                   3550:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3551:        ipmx +=1;
                   3552:        sw += weight[i];
                   3553:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3554:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3555:       } /* end of wave */
                   3556:     } /* end of individual */
                   3557:   } /* End of if */
                   3558:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3559:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3560:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3561:   return -l;
1.126     brouard  3562: }
                   3563: 
                   3564: /*************** log-likelihood *************/
                   3565: double funcone( double *x)
                   3566: {
1.228     brouard  3567:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3568:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3569:   int ioffset=0;
1.131     brouard  3570:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3571:   double **out;
                   3572:   double lli; /* Individual log likelihood */
                   3573:   double llt;
                   3574:   int s1, s2;
1.228     brouard  3575:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3576: 
1.126     brouard  3577:   double bbh, survp;
1.187     brouard  3578:   double agexact;
1.214     brouard  3579:   double agebegin, ageend;
1.126     brouard  3580:   /*extern weight */
                   3581:   /* We are differentiating ll according to initial status */
                   3582:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3583:   /*for(i=1;i<imx;i++) 
                   3584:     printf(" %d\n",s[4][i]);
                   3585:   */
                   3586:   cov[1]=1.;
                   3587: 
                   3588:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3589:   ioffset=0;
                   3590:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3591:     /* ioffset=2+nagesqr+cptcovage; */
                   3592:     ioffset=2+nagesqr;
1.232     brouard  3593:     /* Fixed */
1.224     brouard  3594:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3595:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3596:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3597:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3598: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3599: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3600: /*    cov[2+6]=covar[2][i]; V2  */
                   3601: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3602: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3603: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3604: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3605: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3606: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3607:     }
1.232     brouard  3608:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3609:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3610:     /* } */
1.231     brouard  3611:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3612:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3613:     /* } */
1.225     brouard  3614:     
1.233     brouard  3615: 
                   3616:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3617:     /* Wave varying (but not age varying) */
                   3618:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3619:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3620:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3621:       }
1.232     brouard  3622:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3623:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3624:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3625:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3626:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3627:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3628:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3629:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3630:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3631:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3632:       /* } */
1.126     brouard  3633:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3634:        for (j=1;j<=nlstate+ndeath;j++){
                   3635:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3636:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3637:        }
1.214     brouard  3638:       
                   3639:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3640:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3641:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3642:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3643:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3644:          and mw[mi+1][i]. dh depends on stepm.*/
                   3645:        newm=savm;
1.247     brouard  3646:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3647:        cov[2]=agexact;
                   3648:        if(nagesqr==1)
                   3649:          cov[3]= agexact*agexact;
                   3650:        for (kk=1; kk<=cptcovage;kk++) {
                   3651:          if(!FixedV[Tvar[Tage[kk]]])
                   3652:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3653:          else
                   3654:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3655:        }
                   3656:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3657:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3658:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3659:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3660:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3661:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3662:        savm=oldm;
                   3663:        oldm=newm;
1.126     brouard  3664:       } /* end mult */
                   3665:       
                   3666:       s1=s[mw[mi][i]][i];
                   3667:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3668:       /* if(s2==-1){ */
                   3669:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3670:       /*       /\* exit(1); *\/ */
                   3671:       /* } */
1.126     brouard  3672:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3673:       /* bias is positive if real duration
                   3674:        * is higher than the multiple of stepm and negative otherwise.
                   3675:        */
                   3676:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3677:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3678:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3679:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3680:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3681:        lli= log(survp);
1.126     brouard  3682:       }else if (mle==1){
1.242     brouard  3683:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3684:       } else if(mle==2){
1.242     brouard  3685:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3686:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3687:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3688:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3689:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3690:       } else{  /* mle=0 back to 1 */
1.242     brouard  3691:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3692:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3693:       } /* End of if */
                   3694:       ipmx +=1;
                   3695:       sw += weight[i];
                   3696:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3697:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3698:       if(globpr){
1.246     brouard  3699:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3700:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3701:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3702:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3703:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3704:          llt +=ll[k]*gipmx/gsw;
                   3705:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3706:        }
                   3707:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3708:       }
1.232     brouard  3709:        } /* end of wave */
                   3710: } /* end of individual */
                   3711: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3712: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3713: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3714: if(globpr==0){ /* First time we count the contributions and weights */
                   3715:        gipmx=ipmx;
                   3716:        gsw=sw;
                   3717: }
                   3718: return -l;
1.126     brouard  3719: }
                   3720: 
                   3721: 
                   3722: /*************** function likelione ***********/
                   3723: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3724: {
                   3725:   /* This routine should help understanding what is done with 
                   3726:      the selection of individuals/waves and
                   3727:      to check the exact contribution to the likelihood.
                   3728:      Plotting could be done.
                   3729:    */
                   3730:   int k;
                   3731: 
                   3732:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3733:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3734:     strcat(fileresilk,fileresu);
1.126     brouard  3735:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3736:       printf("Problem with resultfile: %s\n", fileresilk);
                   3737:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3738:     }
1.214     brouard  3739:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3740:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3741:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3742:     for(k=1; k<=nlstate; k++) 
                   3743:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3744:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3745:   }
                   3746: 
                   3747:   *fretone=(*funcone)(p);
                   3748:   if(*globpri !=0){
                   3749:     fclose(ficresilk);
1.205     brouard  3750:     if (mle ==0)
                   3751:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3752:     else if(mle >=1)
                   3753:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3754:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3755:     
1.208     brouard  3756:       
                   3757:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3758:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3759: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3760:     }
1.207     brouard  3761:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3762: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3763:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3764: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3765:     fflush(fichtm);
1.205     brouard  3766:   }
1.126     brouard  3767:   return;
                   3768: }
                   3769: 
                   3770: 
                   3771: /*********** Maximum Likelihood Estimation ***************/
                   3772: 
                   3773: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3774: {
1.165     brouard  3775:   int i,j, iter=0;
1.126     brouard  3776:   double **xi;
                   3777:   double fret;
                   3778:   double fretone; /* Only one call to likelihood */
                   3779:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3780: 
                   3781: #ifdef NLOPT
                   3782:   int creturn;
                   3783:   nlopt_opt opt;
                   3784:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3785:   double *lb;
                   3786:   double minf; /* the minimum objective value, upon return */
                   3787:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3788:   myfunc_data dinst, *d = &dinst;
                   3789: #endif
                   3790: 
                   3791: 
1.126     brouard  3792:   xi=matrix(1,npar,1,npar);
                   3793:   for (i=1;i<=npar;i++)
                   3794:     for (j=1;j<=npar;j++)
                   3795:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3796:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3797:   strcpy(filerespow,"POW_"); 
1.126     brouard  3798:   strcat(filerespow,fileres);
                   3799:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3800:     printf("Problem with resultfile: %s\n", filerespow);
                   3801:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3802:   }
                   3803:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3804:   for (i=1;i<=nlstate;i++)
                   3805:     for(j=1;j<=nlstate+ndeath;j++)
                   3806:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3807:   fprintf(ficrespow,"\n");
1.162     brouard  3808: #ifdef POWELL
1.126     brouard  3809:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3810: #endif
1.126     brouard  3811: 
1.162     brouard  3812: #ifdef NLOPT
                   3813: #ifdef NEWUOA
                   3814:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3815: #else
                   3816:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3817: #endif
                   3818:   lb=vector(0,npar-1);
                   3819:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3820:   nlopt_set_lower_bounds(opt, lb);
                   3821:   nlopt_set_initial_step1(opt, 0.1);
                   3822:   
                   3823:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3824:   d->function = func;
                   3825:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3826:   nlopt_set_min_objective(opt, myfunc, d);
                   3827:   nlopt_set_xtol_rel(opt, ftol);
                   3828:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3829:     printf("nlopt failed! %d\n",creturn); 
                   3830:   }
                   3831:   else {
                   3832:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3833:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3834:     iter=1; /* not equal */
                   3835:   }
                   3836:   nlopt_destroy(opt);
                   3837: #endif
1.126     brouard  3838:   free_matrix(xi,1,npar,1,npar);
                   3839:   fclose(ficrespow);
1.203     brouard  3840:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3841:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3842:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3843: 
                   3844: }
                   3845: 
                   3846: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3847: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3848: {
                   3849:   double  **a,**y,*x,pd;
1.203     brouard  3850:   /* double **hess; */
1.164     brouard  3851:   int i, j;
1.126     brouard  3852:   int *indx;
                   3853: 
                   3854:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3855:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3856:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3857:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3858:   double gompertz(double p[]);
1.203     brouard  3859:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3860: 
                   3861:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3862:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3863:   for (i=1;i<=npar;i++){
1.203     brouard  3864:     printf("%d-",i);fflush(stdout);
                   3865:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3866:    
                   3867:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3868:     
                   3869:     /*  printf(" %f ",p[i]);
                   3870:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3871:   }
                   3872:   
                   3873:   for (i=1;i<=npar;i++) {
                   3874:     for (j=1;j<=npar;j++)  {
                   3875:       if (j>i) { 
1.203     brouard  3876:        printf(".%d-%d",i,j);fflush(stdout);
                   3877:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3878:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3879:        
                   3880:        hess[j][i]=hess[i][j];    
                   3881:        /*printf(" %lf ",hess[i][j]);*/
                   3882:       }
                   3883:     }
                   3884:   }
                   3885:   printf("\n");
                   3886:   fprintf(ficlog,"\n");
                   3887: 
                   3888:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3889:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3890:   
                   3891:   a=matrix(1,npar,1,npar);
                   3892:   y=matrix(1,npar,1,npar);
                   3893:   x=vector(1,npar);
                   3894:   indx=ivector(1,npar);
                   3895:   for (i=1;i<=npar;i++)
                   3896:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3897:   ludcmp(a,npar,indx,&pd);
                   3898: 
                   3899:   for (j=1;j<=npar;j++) {
                   3900:     for (i=1;i<=npar;i++) x[i]=0;
                   3901:     x[j]=1;
                   3902:     lubksb(a,npar,indx,x);
                   3903:     for (i=1;i<=npar;i++){ 
                   3904:       matcov[i][j]=x[i];
                   3905:     }
                   3906:   }
                   3907: 
                   3908:   printf("\n#Hessian matrix#\n");
                   3909:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3910:   for (i=1;i<=npar;i++) { 
                   3911:     for (j=1;j<=npar;j++) { 
1.203     brouard  3912:       printf("%.6e ",hess[i][j]);
                   3913:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3914:     }
                   3915:     printf("\n");
                   3916:     fprintf(ficlog,"\n");
                   3917:   }
                   3918: 
1.203     brouard  3919:   /* printf("\n#Covariance matrix#\n"); */
                   3920:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3921:   /* for (i=1;i<=npar;i++) {  */
                   3922:   /*   for (j=1;j<=npar;j++) {  */
                   3923:   /*     printf("%.6e ",matcov[i][j]); */
                   3924:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3925:   /*   } */
                   3926:   /*   printf("\n"); */
                   3927:   /*   fprintf(ficlog,"\n"); */
                   3928:   /* } */
                   3929: 
1.126     brouard  3930:   /* Recompute Inverse */
1.203     brouard  3931:   /* for (i=1;i<=npar;i++) */
                   3932:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3933:   /* ludcmp(a,npar,indx,&pd); */
                   3934: 
                   3935:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3936: 
                   3937:   /* for (j=1;j<=npar;j++) { */
                   3938:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3939:   /*   x[j]=1; */
                   3940:   /*   lubksb(a,npar,indx,x); */
                   3941:   /*   for (i=1;i<=npar;i++){  */
                   3942:   /*     y[i][j]=x[i]; */
                   3943:   /*     printf("%.3e ",y[i][j]); */
                   3944:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3945:   /*   } */
                   3946:   /*   printf("\n"); */
                   3947:   /*   fprintf(ficlog,"\n"); */
                   3948:   /* } */
                   3949: 
                   3950:   /* Verifying the inverse matrix */
                   3951: #ifdef DEBUGHESS
                   3952:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3953: 
1.203     brouard  3954:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3955:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3956: 
                   3957:   for (j=1;j<=npar;j++) {
                   3958:     for (i=1;i<=npar;i++){ 
1.203     brouard  3959:       printf("%.2f ",y[i][j]);
                   3960:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3961:     }
                   3962:     printf("\n");
                   3963:     fprintf(ficlog,"\n");
                   3964:   }
1.203     brouard  3965: #endif
1.126     brouard  3966: 
                   3967:   free_matrix(a,1,npar,1,npar);
                   3968:   free_matrix(y,1,npar,1,npar);
                   3969:   free_vector(x,1,npar);
                   3970:   free_ivector(indx,1,npar);
1.203     brouard  3971:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3972: 
                   3973: 
                   3974: }
                   3975: 
                   3976: /*************** hessian matrix ****************/
                   3977: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3978: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3979:   int i;
                   3980:   int l=1, lmax=20;
1.203     brouard  3981:   double k1,k2, res, fx;
1.132     brouard  3982:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3983:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3984:   int k=0,kmax=10;
                   3985:   double l1;
                   3986: 
                   3987:   fx=func(x);
                   3988:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3989:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3990:     l1=pow(10,l);
                   3991:     delts=delt;
                   3992:     for(k=1 ; k <kmax; k=k+1){
                   3993:       delt = delta*(l1*k);
                   3994:       p2[theta]=x[theta] +delt;
1.145     brouard  3995:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3996:       p2[theta]=x[theta]-delt;
                   3997:       k2=func(p2)-fx;
                   3998:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3999:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4000:       
1.203     brouard  4001: #ifdef DEBUGHESSII
1.126     brouard  4002:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4003:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4004: #endif
                   4005:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4006:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4007:        k=kmax;
                   4008:       }
                   4009:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4010:        k=kmax; l=lmax*10;
1.126     brouard  4011:       }
                   4012:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4013:        delts=delt;
                   4014:       }
1.203     brouard  4015:     } /* End loop k */
1.126     brouard  4016:   }
                   4017:   delti[theta]=delts;
                   4018:   return res; 
                   4019:   
                   4020: }
                   4021: 
1.203     brouard  4022: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4023: {
                   4024:   int i;
1.164     brouard  4025:   int l=1, lmax=20;
1.126     brouard  4026:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4027:   double p2[MAXPARM+1];
1.203     brouard  4028:   int k, kmax=1;
                   4029:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4030: 
                   4031:   int firstime=0;
1.203     brouard  4032:   
1.126     brouard  4033:   fx=func(x);
1.203     brouard  4034:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4035:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4036:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4037:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4038:     k1=func(p2)-fx;
                   4039:   
1.203     brouard  4040:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4041:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4042:     k2=func(p2)-fx;
                   4043:   
1.203     brouard  4044:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4045:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4046:     k3=func(p2)-fx;
                   4047:   
1.203     brouard  4048:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4049:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4050:     k4=func(p2)-fx;
1.203     brouard  4051:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4052:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4053:       firstime=1;
1.203     brouard  4054:       kmax=kmax+10;
1.208     brouard  4055:     }
                   4056:     if(kmax >=10 || firstime ==1){
1.246     brouard  4057:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4058:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4059:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4060:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4061:     }
                   4062: #ifdef DEBUGHESSIJ
                   4063:     v1=hess[thetai][thetai];
                   4064:     v2=hess[thetaj][thetaj];
                   4065:     cv12=res;
                   4066:     /* Computing eigen value of Hessian matrix */
                   4067:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4068:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4069:     if ((lc2 <0) || (lc1 <0) ){
                   4070:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4071:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4072:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4073:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4074:     }
1.126     brouard  4075: #endif
                   4076:   }
                   4077:   return res;
                   4078: }
                   4079: 
1.203     brouard  4080:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4081: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4082: /* { */
                   4083: /*   int i; */
                   4084: /*   int l=1, lmax=20; */
                   4085: /*   double k1,k2,k3,k4,res,fx; */
                   4086: /*   double p2[MAXPARM+1]; */
                   4087: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4088: /*   int k=0,kmax=10; */
                   4089: /*   double l1; */
                   4090:   
                   4091: /*   fx=func(x); */
                   4092: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4093: /*     l1=pow(10,l); */
                   4094: /*     delts=delt; */
                   4095: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4096: /*       delt = delti*(l1*k); */
                   4097: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4098: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4099: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4100: /*       k1=func(p2)-fx; */
                   4101:       
                   4102: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4103: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4104: /*       k2=func(p2)-fx; */
                   4105:       
                   4106: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4107: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4108: /*       k3=func(p2)-fx; */
                   4109:       
                   4110: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4111: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4112: /*       k4=func(p2)-fx; */
                   4113: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4114: /* #ifdef DEBUGHESSIJ */
                   4115: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4116: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4117: /* #endif */
                   4118: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4119: /*     k=kmax; */
                   4120: /*       } */
                   4121: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4122: /*     k=kmax; l=lmax*10; */
                   4123: /*       } */
                   4124: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4125: /*     delts=delt; */
                   4126: /*       } */
                   4127: /*     } /\* End loop k *\/ */
                   4128: /*   } */
                   4129: /*   delti[theta]=delts; */
                   4130: /*   return res;  */
                   4131: /* } */
                   4132: 
                   4133: 
1.126     brouard  4134: /************** Inverse of matrix **************/
                   4135: void ludcmp(double **a, int n, int *indx, double *d) 
                   4136: { 
                   4137:   int i,imax,j,k; 
                   4138:   double big,dum,sum,temp; 
                   4139:   double *vv; 
                   4140:  
                   4141:   vv=vector(1,n); 
                   4142:   *d=1.0; 
                   4143:   for (i=1;i<=n;i++) { 
                   4144:     big=0.0; 
                   4145:     for (j=1;j<=n;j++) 
                   4146:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4147:     if (big == 0.0){
                   4148:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4149:       for (j=1;j<=n;j++) {
                   4150:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4151:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4152:       }
                   4153:       fflush(ficlog);
                   4154:       fclose(ficlog);
                   4155:       nrerror("Singular matrix in routine ludcmp"); 
                   4156:     }
1.126     brouard  4157:     vv[i]=1.0/big; 
                   4158:   } 
                   4159:   for (j=1;j<=n;j++) { 
                   4160:     for (i=1;i<j;i++) { 
                   4161:       sum=a[i][j]; 
                   4162:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4163:       a[i][j]=sum; 
                   4164:     } 
                   4165:     big=0.0; 
                   4166:     for (i=j;i<=n;i++) { 
                   4167:       sum=a[i][j]; 
                   4168:       for (k=1;k<j;k++) 
                   4169:        sum -= a[i][k]*a[k][j]; 
                   4170:       a[i][j]=sum; 
                   4171:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4172:        big=dum; 
                   4173:        imax=i; 
                   4174:       } 
                   4175:     } 
                   4176:     if (j != imax) { 
                   4177:       for (k=1;k<=n;k++) { 
                   4178:        dum=a[imax][k]; 
                   4179:        a[imax][k]=a[j][k]; 
                   4180:        a[j][k]=dum; 
                   4181:       } 
                   4182:       *d = -(*d); 
                   4183:       vv[imax]=vv[j]; 
                   4184:     } 
                   4185:     indx[j]=imax; 
                   4186:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4187:     if (j != n) { 
                   4188:       dum=1.0/(a[j][j]); 
                   4189:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4190:     } 
                   4191:   } 
                   4192:   free_vector(vv,1,n);  /* Doesn't work */
                   4193: ;
                   4194: } 
                   4195: 
                   4196: void lubksb(double **a, int n, int *indx, double b[]) 
                   4197: { 
                   4198:   int i,ii=0,ip,j; 
                   4199:   double sum; 
                   4200:  
                   4201:   for (i=1;i<=n;i++) { 
                   4202:     ip=indx[i]; 
                   4203:     sum=b[ip]; 
                   4204:     b[ip]=b[i]; 
                   4205:     if (ii) 
                   4206:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4207:     else if (sum) ii=i; 
                   4208:     b[i]=sum; 
                   4209:   } 
                   4210:   for (i=n;i>=1;i--) { 
                   4211:     sum=b[i]; 
                   4212:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4213:     b[i]=sum/a[i][i]; 
                   4214:   } 
                   4215: } 
                   4216: 
                   4217: void pstamp(FILE *fichier)
                   4218: {
1.196     brouard  4219:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4220: }
                   4221: 
1.253     brouard  4222: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4223: 
                   4224:   /* y=a+bx regression */
                   4225:   double   sumx = 0.0;                        /* sum of x                      */
                   4226:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4227:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4228:   double   sumy = 0.0;                        /* sum of y                      */
                   4229:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4230:   double   sume2; /* sum of square or residuals */
                   4231:   double yhat;
                   4232:   
                   4233:   double denom=0;
                   4234:   int i;
                   4235:   int ne=*no;
                   4236:   
                   4237:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4238:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4239:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4240:       continue;
                   4241:     }
                   4242:     ne=ne+1;
                   4243:     sumx  += x[i];       
                   4244:     sumx2 += x[i]*x[i];  
                   4245:     sumxy += x[i] * y[i];
                   4246:     sumy  += y[i];      
                   4247:     sumy2 += y[i]*y[i]; 
                   4248:     denom = (ne * sumx2 - sumx*sumx);
                   4249:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4250:   } 
                   4251:   
                   4252:   denom = (ne * sumx2 - sumx*sumx);
                   4253:   if (denom == 0) {
                   4254:     // vertical, slope m is infinity
                   4255:     *b = INFINITY;
                   4256:     *a = 0;
                   4257:     if (r) *r = 0;
                   4258:     return 1;
                   4259:   }
                   4260:   
                   4261:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4262:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4263:   if (r!=NULL) {
                   4264:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4265:       sqrt((sumx2 - sumx*sumx/ne) *
                   4266:           (sumy2 - sumy*sumy/ne));
                   4267:   }
                   4268:   *no=ne;
                   4269:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4270:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4271:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4272:       continue;
                   4273:     }
                   4274:     ne=ne+1;
                   4275:     yhat = y[i] - *a -*b* x[i];
                   4276:     sume2  += yhat * yhat ;       
                   4277:     
                   4278:     denom = (ne * sumx2 - sumx*sumx);
                   4279:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4280:   } 
                   4281:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4282:   *sa= *sb * sqrt(sumx2/ne);
                   4283:   
                   4284:   return 0; 
                   4285: }
                   4286: 
1.126     brouard  4287: /************ Frequencies ********************/
1.251     brouard  4288: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4289:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4290:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4291: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4292:   
1.253     brouard  4293:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4294:   int iind=0, iage=0;
                   4295:   int mi; /* Effective wave */
                   4296:   int first;
                   4297:   double ***freq; /* Frequencies */
1.253     brouard  4298:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4299:   int no;
1.226     brouard  4300:   double *meanq;
                   4301:   double **meanqt;
                   4302:   double *pp, **prop, *posprop, *pospropt;
                   4303:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4304:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4305:   double agebegin, ageend;
                   4306:     
                   4307:   pp=vector(1,nlstate);
1.251     brouard  4308:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4309:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4310:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4311:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4312:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4313:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4314:   strcpy(fileresp,"P_");
                   4315:   strcat(fileresp,fileresu);
                   4316:   /*strcat(fileresphtm,fileresu);*/
                   4317:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4318:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4319:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4320:     exit(0);
                   4321:   }
1.240     brouard  4322:   
1.226     brouard  4323:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4324:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4325:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4326:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4327:     fflush(ficlog);
                   4328:     exit(70); 
                   4329:   }
                   4330:   else{
                   4331:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4332: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4333: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4334:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4335:   }
1.237     brouard  4336:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4337:   
1.226     brouard  4338:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4339:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4340:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4341:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4342:     fflush(ficlog);
                   4343:     exit(70); 
1.240     brouard  4344:   } else{
1.226     brouard  4345:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4346: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4347: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4348:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4349:   }
1.240     brouard  4350:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4351:   
1.253     brouard  4352:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4353:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4354:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4355:   j1=0;
1.126     brouard  4356:   
1.227     brouard  4357:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4358:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4359:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4360:   
                   4361:   
1.226     brouard  4362:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4363:      reference=low_education V1=0,V2=0
                   4364:      med_educ                V1=1 V2=0, 
                   4365:      high_educ               V1=0 V2=1
                   4366:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4367:   */
1.249     brouard  4368:   dateintsum=0;
                   4369:   k2cpt=0;
                   4370: 
1.253     brouard  4371:   if(cptcoveff == 0 )
                   4372:     nl=1;  /* Constant model only */
                   4373:   else
                   4374:     nl=2;
                   4375:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4376:     if(nj==1)
                   4377:       j=0;  /* First pass for the constant */
                   4378:     else
                   4379:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4380:     first=1;
                   4381:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4382:       posproptt=0.;
                   4383:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4384:        scanf("%d", i);*/
                   4385:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4386:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4387:          for(m=iagemin; m <= iagemax+3; m++)
                   4388:            freq[i][jk][m]=0;
                   4389:       
                   4390:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4391:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4392:          prop[i][m]=0;
                   4393:        posprop[i]=0;
                   4394:        pospropt[i]=0;
                   4395:       }
                   4396:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4397:       /*   meanq[z1]+=0.; */
                   4398:       /*   for(m=1;m<=lastpass;m++){ */
                   4399:       /*       meanqt[m][z1]=0.; */
                   4400:       /*   } */
                   4401:       /* } */
                   4402:       
                   4403:       /* dateintsum=0; */
                   4404:       /* k2cpt=0; */
                   4405:       
                   4406:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4407:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4408:        bool=1;
                   4409:        if(j !=0){
                   4410:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4411:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4412:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4413:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4414:              /* } */
                   4415:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4416:                /* if(Tvaraff[z1] ==-20){ */
                   4417:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4418:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4419:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4420:                /* }else  */
                   4421:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4422:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4423:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4424:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4425:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4426:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4427:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4428:                } /* Onlyf fixed */
                   4429:              } /* end z1 */
                   4430:            } /* cptcovn > 0 */
                   4431:          } /* end any */
                   4432:        }/* end j==0 */
                   4433:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4434:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4435:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4436:            m=mw[mi][iind];
                   4437:            if(j!=0){
                   4438:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4439:                for (z1=1; z1<=cptcoveff; z1++) {
                   4440:                  if( Fixed[Tmodelind[z1]]==1){
                   4441:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4442:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4443:                                                                                      value is -1, we don't select. It differs from the 
                   4444:                                                                                      constant and age model which counts them. */
                   4445:                      bool=0; /* not selected */
                   4446:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4447:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4448:                      bool=0;
                   4449:                    }
                   4450:                  }
                   4451:                }
                   4452:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4453:            } /* end j==0 */
                   4454:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4455:            if(bool==1){
                   4456:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4457:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4458:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4459:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4460:              if(m >=firstpass && m <=lastpass){
                   4461:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4462:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4463:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4464:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4465:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4466:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4467:                if (m<lastpass) {
                   4468:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4469:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4470:                  if(s[m][iind]==-1)
                   4471:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4472:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4473:                  /* if((int)agev[m][iind] == 55) */
                   4474:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4475:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4476:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4477:                }
1.251     brouard  4478:              } /* end if between passes */  
                   4479:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4480:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4481:                k2cpt++;
                   4482:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4483:              }
1.251     brouard  4484:            }else{
                   4485:              bool=1;
                   4486:            }/* end bool 2 */
                   4487:          } /* end m */
                   4488:        } /* end bool */
                   4489:       } /* end iind = 1 to imx */
                   4490:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4491:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4492:       
                   4493:       
                   4494:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4495:       pstamp(ficresp);
                   4496:       if  (cptcoveff>0 && j!=0){
                   4497:        printf( "\n#********** Variable "); 
                   4498:        fprintf(ficresp, "\n#********** Variable "); 
                   4499:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4500:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4501:        fprintf(ficlog, "\n#********** Variable "); 
                   4502:        for (z1=1; z1<=cptcoveff; z1++){
                   4503:          if(!FixedV[Tvaraff[z1]]){
                   4504:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4505:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4506:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4507:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4508:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4509:          }else{
1.251     brouard  4510:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4511:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4512:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4513:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4514:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4515:          }
                   4516:        }
                   4517:        printf( "**********\n#");
                   4518:        fprintf(ficresp, "**********\n#");
                   4519:        fprintf(ficresphtm, "**********</h3>\n");
                   4520:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4521:        fprintf(ficlog, "**********\n");
                   4522:       }
                   4523:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4524:       for(i=1; i<=nlstate;i++) {
                   4525:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4526:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4527:       }
                   4528:       fprintf(ficresp, "\n");
                   4529:       fprintf(ficresphtm, "\n");
                   4530:       
                   4531:       /* Header of frequency table by age */
                   4532:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4533:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4534:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4535:        for(m=-1; m <=nlstate+ndeath; m++){
                   4536:          if(jk!=0 && m!=0)
                   4537:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4538:        }
1.226     brouard  4539:       }
1.251     brouard  4540:       fprintf(ficresphtmfr, "\n");
                   4541:     
                   4542:       /* For each age */
                   4543:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4544:        fprintf(ficresphtm,"<tr>");
                   4545:        if(iage==iagemax+1){
                   4546:          fprintf(ficlog,"1");
                   4547:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4548:        }else if(iage==iagemax+2){
                   4549:          fprintf(ficlog,"0");
                   4550:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4551:        }else if(iage==iagemax+3){
                   4552:          fprintf(ficlog,"Total");
                   4553:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4554:        }else{
1.240     brouard  4555:          if(first==1){
1.251     brouard  4556:            first=0;
                   4557:            printf("See log file for details...\n");
                   4558:          }
                   4559:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4560:          fprintf(ficlog,"Age %d", iage);
                   4561:        }
                   4562:        for(jk=1; jk <=nlstate ; jk++){
                   4563:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4564:            pp[jk] += freq[jk][m][iage]; 
                   4565:        }
                   4566:        for(jk=1; jk <=nlstate ; jk++){
                   4567:          for(m=-1, pos=0; m <=0 ; m++)
                   4568:            pos += freq[jk][m][iage];
                   4569:          if(pp[jk]>=1.e-10){
                   4570:            if(first==1){
                   4571:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4572:            }
                   4573:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4574:          }else{
                   4575:            if(first==1)
                   4576:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4577:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4578:          }
                   4579:        }
                   4580:       
1.251     brouard  4581:        for(jk=1; jk <=nlstate ; jk++){ 
                   4582:          /* posprop[jk]=0; */
                   4583:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4584:            pp[jk] += freq[jk][m][iage];
                   4585:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4586:       
                   4587:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4588:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4589:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4590:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4591:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4592:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4593:        }
1.251     brouard  4594:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4595:          if(pos>=1.e-5){
1.251     brouard  4596:            if(first==1)
                   4597:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4598:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4599:          }else{
                   4600:            if(first==1)
                   4601:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4602:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4603:          }
                   4604:          if( iage <= iagemax){
                   4605:            if(pos>=1.e-5){
                   4606:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4607:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4608:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4609:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4610:            }
                   4611:            else{
                   4612:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4613:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4614:            }
1.240     brouard  4615:          }
1.251     brouard  4616:          pospropt[jk] +=posprop[jk];
                   4617:        } /* end loop jk */
                   4618:        /* pospropt=0.; */
                   4619:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4620:          for(m=-1; m <=nlstate+ndeath; m++){
                   4621:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4622:              if(first==1){
                   4623:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4624:              }
1.253     brouard  4625:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4626:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4627:            }
                   4628:            if(jk!=0 && m!=0)
                   4629:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4630:          }
1.251     brouard  4631:        } /* end loop jk */
                   4632:        posproptt=0.; 
                   4633:        for(jk=1; jk <=nlstate; jk++){
                   4634:          posproptt += pospropt[jk];
                   4635:        }
                   4636:        fprintf(ficresphtmfr,"</tr>\n ");
                   4637:        if(iage <= iagemax){
                   4638:          fprintf(ficresp,"\n");
                   4639:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4640:        }
1.251     brouard  4641:        if(first==1)
                   4642:          printf("Others in log...\n");
                   4643:        fprintf(ficlog,"\n");
                   4644:       } /* end loop age iage */
                   4645:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4646:       for(jk=1; jk <=nlstate ; jk++){
                   4647:        if(posproptt < 1.e-5){
                   4648:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4649:        }else{
                   4650:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4651:        }
1.226     brouard  4652:       }
1.251     brouard  4653:       fprintf(ficresphtm,"</tr>\n");
                   4654:       fprintf(ficresphtm,"</table>\n");
                   4655:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4656:       if(posproptt < 1.e-5){
1.251     brouard  4657:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4658:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4659:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4660:        invalidvarcomb[j1]=1;
1.226     brouard  4661:       }else{
1.251     brouard  4662:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4663:        invalidvarcomb[j1]=0;
1.226     brouard  4664:       }
1.251     brouard  4665:       fprintf(ficresphtmfr,"</table>\n");
                   4666:       fprintf(ficlog,"\n");
                   4667:       if(j!=0){
                   4668:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4669:        for(i=1,jk=1; i <=nlstate; i++){
                   4670:          for(k=1; k <=(nlstate+ndeath); k++){
                   4671:            if (k != i) {
                   4672:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4673:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4674:                  if(j1==1){ /* All dummy covariates to zero */
                   4675:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4676:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4677:                    printf("%d%d ",i,k);
                   4678:                    fprintf(ficlog,"%d%d ",i,k);
                   4679:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4680:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4681:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4682:                  }
1.253     brouard  4683:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4684:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4685:                    x[iage]= (double)iage;
                   4686:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4687:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4688:                  }
                   4689:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4690:                  pstart[jk]=b;
                   4691:                  pstart[jk-1]=a;
1.252     brouard  4692:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4693:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4694:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4695:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4696:                  printf("%d%d ",i,k);
                   4697:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4698:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4699:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4700:                  ;
                   4701:                }
                   4702:                /* printf("%12.7f )", param[i][jj][k]); */
                   4703:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4704:                jk++; 
                   4705:              } /* end jj */
                   4706:            } /* end k!= i */
                   4707:          } /* end k */
                   4708:        } /* end i, jk */
                   4709:       } /* end j !=0 */
                   4710:     } /* end selected combination of covariate j1 */
                   4711:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4712:       printf("#Freqsummary: Starting values for the constants:\n");
                   4713:       fprintf(ficlog,"\n");
                   4714:       for(i=1,jk=1; i <=nlstate; i++){
                   4715:        for(k=1; k <=(nlstate+ndeath); k++){
                   4716:          if (k != i) {
                   4717:            printf("%d%d ",i,k);
                   4718:            fprintf(ficlog,"%d%d ",i,k);
                   4719:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4720:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4721:              if(jj==1){ /* Age has to be done */
                   4722:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4723:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4724:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4725:              }
                   4726:              /* printf("%12.7f )", param[i][jj][k]); */
                   4727:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4728:              jk++; 
1.250     brouard  4729:            }
1.251     brouard  4730:            printf("\n");
                   4731:            fprintf(ficlog,"\n");
1.250     brouard  4732:          }
                   4733:        }
                   4734:       }
1.251     brouard  4735:       printf("#Freqsummary\n");
                   4736:       fprintf(ficlog,"\n");
                   4737:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4738:        for(m=-1; m <=nlstate+ndeath; m++){
                   4739:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4740:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4741:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4742:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4743:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4744:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4745:          /* } */
                   4746:        }
                   4747:       } /* end loop jk */
                   4748:       
                   4749:       printf("\n");
                   4750:       fprintf(ficlog,"\n");
                   4751:     } /* end j=0 */
1.249     brouard  4752:   } /* end j */
1.252     brouard  4753: 
1.253     brouard  4754:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4755:     for(i=1, jk=1; i <=nlstate; i++){
                   4756:       for(j=1; j <=nlstate+ndeath; j++){
                   4757:        if(j!=i){
                   4758:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4759:          printf("%1d%1d",i,j);
                   4760:          fprintf(ficparo,"%1d%1d",i,j);
                   4761:          for(k=1; k<=ncovmodel;k++){
                   4762:            /*    printf(" %lf",param[i][j][k]); */
                   4763:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4764:            p[jk]=pstart[jk];
                   4765:            printf(" %f ",pstart[jk]);
                   4766:            fprintf(ficparo," %f ",pstart[jk]);
                   4767:            jk++;
                   4768:          }
                   4769:          printf("\n");
                   4770:          fprintf(ficparo,"\n");
                   4771:        }
                   4772:       }
                   4773:     }
                   4774:   } /* end mle=-2 */
1.226     brouard  4775:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4776:   
1.226     brouard  4777:   fclose(ficresp);
                   4778:   fclose(ficresphtm);
                   4779:   fclose(ficresphtmfr);
                   4780:   free_vector(meanq,1,nqfveff);
                   4781:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4782:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4783:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4784:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4785:   free_vector(pospropt,1,nlstate);
                   4786:   free_vector(posprop,1,nlstate);
1.251     brouard  4787:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4788:   free_vector(pp,1,nlstate);
                   4789:   /* End of freqsummary */
                   4790: }
1.126     brouard  4791: 
                   4792: /************ Prevalence ********************/
1.227     brouard  4793: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4794: {  
                   4795:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4796:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4797:      We still use firstpass and lastpass as another selection.
                   4798:   */
1.126     brouard  4799:  
1.227     brouard  4800:   int i, m, jk, j1, bool, z1,j, iv;
                   4801:   int mi; /* Effective wave */
                   4802:   int iage;
                   4803:   double agebegin, ageend;
                   4804: 
                   4805:   double **prop;
                   4806:   double posprop; 
                   4807:   double  y2; /* in fractional years */
                   4808:   int iagemin, iagemax;
                   4809:   int first; /** to stop verbosity which is redirected to log file */
                   4810: 
                   4811:   iagemin= (int) agemin;
                   4812:   iagemax= (int) agemax;
                   4813:   /*pp=vector(1,nlstate);*/
1.251     brouard  4814:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4815:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4816:   j1=0;
1.222     brouard  4817:   
1.227     brouard  4818:   /*j=cptcoveff;*/
                   4819:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4820:   
1.227     brouard  4821:   first=1;
                   4822:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4823:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4824:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4825:        prop[i][iage]=0.0;
                   4826:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4827:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4828:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4829:     
                   4830:     for (i=1; i<=imx; i++) { /* Each individual */
                   4831:       bool=1;
                   4832:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4833:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4834:        m=mw[mi][i];
                   4835:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4836:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4837:        for (z1=1; z1<=cptcoveff; z1++){
                   4838:          if( Fixed[Tmodelind[z1]]==1){
                   4839:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4840:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4841:              bool=0;
                   4842:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4843:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4844:              bool=0;
                   4845:            }
                   4846:        }
                   4847:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4848:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4849:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4850:          if(m >=firstpass && m <=lastpass){
                   4851:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4852:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4853:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4854:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4855:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4856:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4857:                exit(1);
                   4858:              }
                   4859:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4860:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4861:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4862:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4863:              } /* end valid statuses */ 
                   4864:            } /* end selection of dates */
                   4865:          } /* end selection of waves */
                   4866:        } /* end bool */
                   4867:       } /* end wave */
                   4868:     } /* end individual */
                   4869:     for(i=iagemin; i <= iagemax+3; i++){  
                   4870:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4871:        posprop += prop[jk][i]; 
                   4872:       } 
                   4873:       
                   4874:       for(jk=1; jk <=nlstate ; jk++){      
                   4875:        if( i <=  iagemax){ 
                   4876:          if(posprop>=1.e-5){ 
                   4877:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4878:          } else{
                   4879:            if(first==1){
                   4880:              first=0;
                   4881:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4882:            }
                   4883:          }
                   4884:        } 
                   4885:       }/* end jk */ 
                   4886:     }/* end i */ 
1.222     brouard  4887:      /*} *//* end i1 */
1.227     brouard  4888:   } /* end j1 */
1.222     brouard  4889:   
1.227     brouard  4890:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4891:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4892:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4893: }  /* End of prevalence */
1.126     brouard  4894: 
                   4895: /************* Waves Concatenation ***************/
                   4896: 
                   4897: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4898: {
                   4899:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4900:      Death is a valid wave (if date is known).
                   4901:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4902:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4903:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4904:   */
1.126     brouard  4905: 
1.224     brouard  4906:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4907:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4908:      double sum=0., jmean=0.;*/
1.224     brouard  4909:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4910:   int j, k=0,jk, ju, jl;
                   4911:   double sum=0.;
                   4912:   first=0;
1.214     brouard  4913:   firstwo=0;
1.217     brouard  4914:   firsthree=0;
1.218     brouard  4915:   firstfour=0;
1.164     brouard  4916:   jmin=100000;
1.126     brouard  4917:   jmax=-1;
                   4918:   jmean=0.;
1.224     brouard  4919: 
                   4920: /* Treating live states */
1.214     brouard  4921:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4922:     mi=0;  /* First valid wave */
1.227     brouard  4923:     mli=0; /* Last valid wave */
1.126     brouard  4924:     m=firstpass;
1.214     brouard  4925:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4926:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4927:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4928:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4929:        mw[++mi][i]=m;
                   4930:        mli=m;
1.224     brouard  4931:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4932:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4933:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4934:       }
1.227     brouard  4935:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4936: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4937:        break;
1.224     brouard  4938: #else
1.227     brouard  4939:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4940:          if(firsthree == 0){
                   4941:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4942:            firsthree=1;
                   4943:          }
                   4944:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4945:          mw[++mi][i]=m;
                   4946:          mli=m;
                   4947:        }
                   4948:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4949:          nbwarn++;
                   4950:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4951:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4952:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4953:          }
                   4954:          break;
                   4955:        }
                   4956:        break;
1.224     brouard  4957: #endif
1.227     brouard  4958:       }/* End m >= lastpass */
1.126     brouard  4959:     }/* end while */
1.224     brouard  4960: 
1.227     brouard  4961:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4962:     /* After last pass */
1.224     brouard  4963: /* Treating death states */
1.214     brouard  4964:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4965:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4966:       /* } */
1.126     brouard  4967:       mi++;    /* Death is another wave */
                   4968:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4969:       /* Only death is a correct wave */
1.126     brouard  4970:       mw[mi][i]=m;
1.257     brouard  4971:     } /* else not in a death state */
1.224     brouard  4972: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4973:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4974:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4975:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4976:          nbwarn++;
                   4977:          if(firstfiv==0){
                   4978:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4979:            firstfiv=1;
                   4980:          }else{
                   4981:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4982:          }
                   4983:        }else{ /* Death occured afer last wave potential bias */
                   4984:          nberr++;
                   4985:          if(firstwo==0){
1.257     brouard  4986:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4987:            firstwo=1;
                   4988:          }
1.257     brouard  4989:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4990:        }
1.257     brouard  4991:       }else{ /* if date of interview is unknown */
1.227     brouard  4992:        /* death is known but not confirmed by death status at any wave */
                   4993:        if(firstfour==0){
                   4994:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4995:          firstfour=1;
                   4996:        }
                   4997:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4998:       }
1.224     brouard  4999:     } /* end if date of death is known */
                   5000: #endif
                   5001:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5002:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5003:     if(mi==0){
                   5004:       nbwarn++;
                   5005:       if(first==0){
1.227     brouard  5006:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5007:        first=1;
1.126     brouard  5008:       }
                   5009:       if(first==1){
1.227     brouard  5010:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5011:       }
                   5012:     } /* end mi==0 */
                   5013:   } /* End individuals */
1.214     brouard  5014:   /* wav and mw are no more changed */
1.223     brouard  5015:        
1.214     brouard  5016:   
1.126     brouard  5017:   for(i=1; i<=imx; i++){
                   5018:     for(mi=1; mi<wav[i];mi++){
                   5019:       if (stepm <=0)
1.227     brouard  5020:        dh[mi][i]=1;
1.126     brouard  5021:       else{
1.227     brouard  5022:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   5023:          if (agedc[i] < 2*AGESUP) {
                   5024:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5025:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5026:            else if(j<0){
                   5027:              nberr++;
                   5028:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5029:              j=1; /* Temporary Dangerous patch */
                   5030:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5031:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5032:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5033:            }
                   5034:            k=k+1;
                   5035:            if (j >= jmax){
                   5036:              jmax=j;
                   5037:              ijmax=i;
                   5038:            }
                   5039:            if (j <= jmin){
                   5040:              jmin=j;
                   5041:              ijmin=i;
                   5042:            }
                   5043:            sum=sum+j;
                   5044:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5045:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5046:          }
                   5047:        }
                   5048:        else{
                   5049:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5050: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5051:                                        
1.227     brouard  5052:          k=k+1;
                   5053:          if (j >= jmax) {
                   5054:            jmax=j;
                   5055:            ijmax=i;
                   5056:          }
                   5057:          else if (j <= jmin){
                   5058:            jmin=j;
                   5059:            ijmin=i;
                   5060:          }
                   5061:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5062:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5063:          if(j<0){
                   5064:            nberr++;
                   5065:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5066:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5067:          }
                   5068:          sum=sum+j;
                   5069:        }
                   5070:        jk= j/stepm;
                   5071:        jl= j -jk*stepm;
                   5072:        ju= j -(jk+1)*stepm;
                   5073:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5074:          if(jl==0){
                   5075:            dh[mi][i]=jk;
                   5076:            bh[mi][i]=0;
                   5077:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5078:                  * to avoid the price of an extra matrix product in likelihood */
                   5079:            dh[mi][i]=jk+1;
                   5080:            bh[mi][i]=ju;
                   5081:          }
                   5082:        }else{
                   5083:          if(jl <= -ju){
                   5084:            dh[mi][i]=jk;
                   5085:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5086:                                 * is higher than the multiple of stepm and negative otherwise.
                   5087:                                 */
                   5088:          }
                   5089:          else{
                   5090:            dh[mi][i]=jk+1;
                   5091:            bh[mi][i]=ju;
                   5092:          }
                   5093:          if(dh[mi][i]==0){
                   5094:            dh[mi][i]=1; /* At least one step */
                   5095:            bh[mi][i]=ju; /* At least one step */
                   5096:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5097:          }
                   5098:        } /* end if mle */
1.126     brouard  5099:       }
                   5100:     } /* end wave */
                   5101:   }
                   5102:   jmean=sum/k;
                   5103:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5104:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5105: }
1.126     brouard  5106: 
                   5107: /*********** Tricode ****************************/
1.220     brouard  5108:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5109:  {
                   5110:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5111:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5112:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5113:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5114:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5115:     */
1.130     brouard  5116: 
1.242     brouard  5117:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5118:    int modmaxcovj=0; /* Modality max of covariates j */
                   5119:    int cptcode=0; /* Modality max of covariates j */
                   5120:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5121: 
                   5122: 
1.242     brouard  5123:    /* cptcoveff=0;  */
                   5124:    /* *cptcov=0; */
1.126     brouard  5125:  
1.242     brouard  5126:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5127: 
1.242     brouard  5128:    /* Loop on covariates without age and products and no quantitative variable */
                   5129:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5130:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5131:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5132:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5133:        switch(Fixed[k]) {
                   5134:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5135:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5136:           ij=(int)(covar[Tvar[k]][i]);
                   5137:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5138:            * If product of Vn*Vm, still boolean *:
                   5139:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5140:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5141:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5142:              modality of the nth covariate of individual i. */
                   5143:           if (ij > modmaxcovj)
                   5144:             modmaxcovj=ij; 
                   5145:           else if (ij < modmincovj) 
                   5146:             modmincovj=ij; 
                   5147:           if ((ij < -1) && (ij > NCOVMAX)){
                   5148:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5149:             exit(1);
                   5150:           }else
                   5151:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5152:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5153:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5154:           /* getting the maximum value of the modality of the covariate
                   5155:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5156:              female ies 1, then modmaxcovj=1.
                   5157:           */
                   5158:         } /* end for loop on individuals i */
                   5159:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5160:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5161:         cptcode=modmaxcovj;
                   5162:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5163:         /*for (i=0; i<=cptcode; i++) {*/
                   5164:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5165:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5166:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5167:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5168:             if( j != -1){
                   5169:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5170:                                  covariate for which somebody answered excluding 
                   5171:                                  undefined. Usually 2: 0 and 1. */
                   5172:             }
                   5173:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5174:                                     covariate for which somebody answered including 
                   5175:                                     undefined. Usually 3: -1, 0 and 1. */
                   5176:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5177:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5178:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5179:                        
1.242     brouard  5180:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5181:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5182:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5183:         /* modmincovj=3; modmaxcovj = 7; */
                   5184:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5185:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5186:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5187:         /* nbcode[Tvar[j]][ij]=k; */
                   5188:         /* nbcode[Tvar[j]][1]=0; */
                   5189:         /* nbcode[Tvar[j]][2]=1; */
                   5190:         /* nbcode[Tvar[j]][3]=2; */
                   5191:         /* To be continued (not working yet). */
                   5192:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5193:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5194:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5195:             break;
                   5196:           }
                   5197:           ij++;
                   5198:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5199:           cptcode = ij; /* New max modality for covar j */
                   5200:         } /* end of loop on modality i=-1 to 1 or more */
                   5201:         break;
                   5202:        case 1: /* Testing on varying covariate, could be simple and
                   5203:                * should look at waves or product of fixed *
                   5204:                * varying. No time to test -1, assuming 0 and 1 only */
                   5205:         ij=0;
                   5206:         for(i=0; i<=1;i++){
                   5207:           nbcode[Tvar[k]][++ij]=i;
                   5208:         }
                   5209:         break;
                   5210:        default:
                   5211:         break;
                   5212:        } /* end switch */
                   5213:      } /* end dummy test */
                   5214:     
                   5215:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5216:      /*        /\*recode from 0 *\/ */
                   5217:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5218:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5219:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5220:      /*        } */
                   5221:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5222:      /*        if (ij > ncodemax[j]) { */
                   5223:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5224:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5225:      /*          break; */
                   5226:      /*        } */
                   5227:      /*   }  /\* end of loop on modality k *\/ */
                   5228:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5229:   
                   5230:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5231:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5232:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5233:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5234:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5235:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5236:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5237:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5238:   
                   5239:    ij=0;
                   5240:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5241:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5242:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5243:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5244:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5245:        /* If product not in single variable we don't print results */
                   5246:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5247:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5248:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5249:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5250:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5251:        if(Fixed[k]!=0)
                   5252:         anyvaryingduminmodel=1;
                   5253:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5254:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5255:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5256:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5257:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5258:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5259:      } 
                   5260:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5261:    /* ij--; */
                   5262:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5263:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5264:                * because they can be excluded from the model and real
                   5265:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5266:    for(j=ij+1; j<= cptcovt; j++){
                   5267:      Tvaraff[j]=0;
                   5268:      Tmodelind[j]=0;
                   5269:    }
                   5270:    for(j=ntveff+1; j<= cptcovt; j++){
                   5271:      TmodelInvind[j]=0;
                   5272:    }
                   5273:    /* To be sorted */
                   5274:    ;
                   5275:  }
1.126     brouard  5276: 
1.145     brouard  5277: 
1.126     brouard  5278: /*********** Health Expectancies ****************/
                   5279: 
1.235     brouard  5280:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5281: 
                   5282: {
                   5283:   /* Health expectancies, no variances */
1.164     brouard  5284:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5285:   int nhstepma, nstepma; /* Decreasing with age */
                   5286:   double age, agelim, hf;
                   5287:   double ***p3mat;
                   5288:   double eip;
                   5289: 
1.238     brouard  5290:   /* pstamp(ficreseij); */
1.126     brouard  5291:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5292:   fprintf(ficreseij,"# Age");
                   5293:   for(i=1; i<=nlstate;i++){
                   5294:     for(j=1; j<=nlstate;j++){
                   5295:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5296:     }
                   5297:     fprintf(ficreseij," e%1d. ",i);
                   5298:   }
                   5299:   fprintf(ficreseij,"\n");
                   5300: 
                   5301:   
                   5302:   if(estepm < stepm){
                   5303:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5304:   }
                   5305:   else  hstepm=estepm;   
                   5306:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5307:    * This is mainly to measure the difference between two models: for example
                   5308:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5309:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5310:    * progression in between and thus overestimating or underestimating according
                   5311:    * to the curvature of the survival function. If, for the same date, we 
                   5312:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5313:    * to compare the new estimate of Life expectancy with the same linear 
                   5314:    * hypothesis. A more precise result, taking into account a more precise
                   5315:    * curvature will be obtained if estepm is as small as stepm. */
                   5316: 
                   5317:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5318:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5319:      nhstepm is the number of hstepm from age to agelim 
                   5320:      nstepm is the number of stepm from age to agelin. 
                   5321:      Look at hpijx to understand the reason of that which relies in memory size
                   5322:      and note for a fixed period like estepm months */
                   5323:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5324:      survival function given by stepm (the optimization length). Unfortunately it
                   5325:      means that if the survival funtion is printed only each two years of age and if
                   5326:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5327:      results. So we changed our mind and took the option of the best precision.
                   5328:   */
                   5329:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5330: 
                   5331:   agelim=AGESUP;
                   5332:   /* If stepm=6 months */
                   5333:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5334:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5335:     
                   5336: /* nhstepm age range expressed in number of stepm */
                   5337:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5338:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5339:   /* if (stepm >= YEARM) hstepm=1;*/
                   5340:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5341:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5342: 
                   5343:   for (age=bage; age<=fage; age ++){ 
                   5344:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5345:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5346:     /* if (stepm >= YEARM) hstepm=1;*/
                   5347:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5348: 
                   5349:     /* If stepm=6 months */
                   5350:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5351:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5352:     
1.235     brouard  5353:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5354:     
                   5355:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5356:     
                   5357:     printf("%d|",(int)age);fflush(stdout);
                   5358:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5359:     
                   5360:     /* Computing expectancies */
                   5361:     for(i=1; i<=nlstate;i++)
                   5362:       for(j=1; j<=nlstate;j++)
                   5363:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5364:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5365:          
                   5366:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5367: 
                   5368:        }
                   5369: 
                   5370:     fprintf(ficreseij,"%3.0f",age );
                   5371:     for(i=1; i<=nlstate;i++){
                   5372:       eip=0;
                   5373:       for(j=1; j<=nlstate;j++){
                   5374:        eip +=eij[i][j][(int)age];
                   5375:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5376:       }
                   5377:       fprintf(ficreseij,"%9.4f", eip );
                   5378:     }
                   5379:     fprintf(ficreseij,"\n");
                   5380:     
                   5381:   }
                   5382:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5383:   printf("\n");
                   5384:   fprintf(ficlog,"\n");
                   5385:   
                   5386: }
                   5387: 
1.235     brouard  5388:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5389: 
                   5390: {
                   5391:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5392:      to initial status i, ei. .
1.126     brouard  5393:   */
                   5394:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5395:   int nhstepma, nstepma; /* Decreasing with age */
                   5396:   double age, agelim, hf;
                   5397:   double ***p3matp, ***p3matm, ***varhe;
                   5398:   double **dnewm,**doldm;
                   5399:   double *xp, *xm;
                   5400:   double **gp, **gm;
                   5401:   double ***gradg, ***trgradg;
                   5402:   int theta;
                   5403: 
                   5404:   double eip, vip;
                   5405: 
                   5406:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5407:   xp=vector(1,npar);
                   5408:   xm=vector(1,npar);
                   5409:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5410:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5411:   
                   5412:   pstamp(ficresstdeij);
                   5413:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5414:   fprintf(ficresstdeij,"# Age");
                   5415:   for(i=1; i<=nlstate;i++){
                   5416:     for(j=1; j<=nlstate;j++)
                   5417:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5418:     fprintf(ficresstdeij," e%1d. ",i);
                   5419:   }
                   5420:   fprintf(ficresstdeij,"\n");
                   5421: 
                   5422:   pstamp(ficrescveij);
                   5423:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5424:   fprintf(ficrescveij,"# Age");
                   5425:   for(i=1; i<=nlstate;i++)
                   5426:     for(j=1; j<=nlstate;j++){
                   5427:       cptj= (j-1)*nlstate+i;
                   5428:       for(i2=1; i2<=nlstate;i2++)
                   5429:        for(j2=1; j2<=nlstate;j2++){
                   5430:          cptj2= (j2-1)*nlstate+i2;
                   5431:          if(cptj2 <= cptj)
                   5432:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5433:        }
                   5434:     }
                   5435:   fprintf(ficrescveij,"\n");
                   5436:   
                   5437:   if(estepm < stepm){
                   5438:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5439:   }
                   5440:   else  hstepm=estepm;   
                   5441:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5442:    * This is mainly to measure the difference between two models: for example
                   5443:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5444:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5445:    * progression in between and thus overestimating or underestimating according
                   5446:    * to the curvature of the survival function. If, for the same date, we 
                   5447:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5448:    * to compare the new estimate of Life expectancy with the same linear 
                   5449:    * hypothesis. A more precise result, taking into account a more precise
                   5450:    * curvature will be obtained if estepm is as small as stepm. */
                   5451: 
                   5452:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5453:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5454:      nhstepm is the number of hstepm from age to agelim 
                   5455:      nstepm is the number of stepm from age to agelin. 
                   5456:      Look at hpijx to understand the reason of that which relies in memory size
                   5457:      and note for a fixed period like estepm months */
                   5458:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5459:      survival function given by stepm (the optimization length). Unfortunately it
                   5460:      means that if the survival funtion is printed only each two years of age and if
                   5461:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5462:      results. So we changed our mind and took the option of the best precision.
                   5463:   */
                   5464:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5465: 
                   5466:   /* If stepm=6 months */
                   5467:   /* nhstepm age range expressed in number of stepm */
                   5468:   agelim=AGESUP;
                   5469:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5470:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5471:   /* if (stepm >= YEARM) hstepm=1;*/
                   5472:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5473:   
                   5474:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5475:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5476:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5477:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5478:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5479:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5480: 
                   5481:   for (age=bage; age<=fage; age ++){ 
                   5482:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5483:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5484:     /* if (stepm >= YEARM) hstepm=1;*/
                   5485:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5486:                
1.126     brouard  5487:     /* If stepm=6 months */
                   5488:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5489:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5490:     
                   5491:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5492:                
1.126     brouard  5493:     /* Computing  Variances of health expectancies */
                   5494:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5495:        decrease memory allocation */
                   5496:     for(theta=1; theta <=npar; theta++){
                   5497:       for(i=1; i<=npar; i++){ 
1.222     brouard  5498:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5499:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5500:       }
1.235     brouard  5501:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5502:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5503:                        
1.126     brouard  5504:       for(j=1; j<= nlstate; j++){
1.222     brouard  5505:        for(i=1; i<=nlstate; i++){
                   5506:          for(h=0; h<=nhstepm-1; h++){
                   5507:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5508:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5509:          }
                   5510:        }
1.126     brouard  5511:       }
1.218     brouard  5512:                        
1.126     brouard  5513:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5514:        for(h=0; h<=nhstepm-1; h++){
                   5515:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5516:        }
1.126     brouard  5517:     }/* End theta */
                   5518:     
                   5519:     
                   5520:     for(h=0; h<=nhstepm-1; h++)
                   5521:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5522:        for(theta=1; theta <=npar; theta++)
                   5523:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5524:     
1.218     brouard  5525:                
1.222     brouard  5526:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5527:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5528:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5529:                
1.222     brouard  5530:     printf("%d|",(int)age);fflush(stdout);
                   5531:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5532:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5533:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5534:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5535:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5536:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5537:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5538:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5539:       }
                   5540:     }
1.218     brouard  5541:                
1.126     brouard  5542:     /* Computing expectancies */
1.235     brouard  5543:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5544:     for(i=1; i<=nlstate;i++)
                   5545:       for(j=1; j<=nlstate;j++)
1.222     brouard  5546:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5547:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5548:                                        
1.222     brouard  5549:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5550:                                        
1.222     brouard  5551:        }
1.218     brouard  5552:                
1.126     brouard  5553:     fprintf(ficresstdeij,"%3.0f",age );
                   5554:     for(i=1; i<=nlstate;i++){
                   5555:       eip=0.;
                   5556:       vip=0.;
                   5557:       for(j=1; j<=nlstate;j++){
1.222     brouard  5558:        eip += eij[i][j][(int)age];
                   5559:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5560:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5561:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5562:       }
                   5563:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5564:     }
                   5565:     fprintf(ficresstdeij,"\n");
1.218     brouard  5566:                
1.126     brouard  5567:     fprintf(ficrescveij,"%3.0f",age );
                   5568:     for(i=1; i<=nlstate;i++)
                   5569:       for(j=1; j<=nlstate;j++){
1.222     brouard  5570:        cptj= (j-1)*nlstate+i;
                   5571:        for(i2=1; i2<=nlstate;i2++)
                   5572:          for(j2=1; j2<=nlstate;j2++){
                   5573:            cptj2= (j2-1)*nlstate+i2;
                   5574:            if(cptj2 <= cptj)
                   5575:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5576:          }
1.126     brouard  5577:       }
                   5578:     fprintf(ficrescveij,"\n");
1.218     brouard  5579:                
1.126     brouard  5580:   }
                   5581:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5582:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5583:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5584:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5585:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5586:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5587:   printf("\n");
                   5588:   fprintf(ficlog,"\n");
1.218     brouard  5589:        
1.126     brouard  5590:   free_vector(xm,1,npar);
                   5591:   free_vector(xp,1,npar);
                   5592:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5593:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5594:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5595: }
1.218     brouard  5596:  
1.126     brouard  5597: /************ Variance ******************/
1.235     brouard  5598:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5599:  {
                   5600:    /* Variance of health expectancies */
                   5601:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5602:    /* double **newm;*/
                   5603:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5604:   
                   5605:    /* int movingaverage(); */
                   5606:    double **dnewm,**doldm;
                   5607:    double **dnewmp,**doldmp;
                   5608:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5609:    int k;
                   5610:    double *xp;
                   5611:    double **gp, **gm;  /* for var eij */
                   5612:    double ***gradg, ***trgradg; /*for var eij */
                   5613:    double **gradgp, **trgradgp; /* for var p point j */
                   5614:    double *gpp, *gmp; /* for var p point j */
                   5615:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5616:    double ***p3mat;
                   5617:    double age,agelim, hf;
                   5618:    /* double ***mobaverage; */
                   5619:    int theta;
                   5620:    char digit[4];
                   5621:    char digitp[25];
                   5622: 
                   5623:    char fileresprobmorprev[FILENAMELENGTH];
                   5624: 
                   5625:    if(popbased==1){
                   5626:      if(mobilav!=0)
                   5627:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5628:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5629:    }
                   5630:    else 
                   5631:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5632: 
1.218     brouard  5633:    /* if (mobilav!=0) { */
                   5634:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5635:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5636:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5637:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5638:    /*   } */
                   5639:    /* } */
                   5640: 
                   5641:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5642:    sprintf(digit,"%-d",ij);
                   5643:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5644:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5645:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5646:    strcat(fileresprobmorprev,fileresu);
                   5647:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5648:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5649:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5650:    }
                   5651:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5652:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5653:    pstamp(ficresprobmorprev);
                   5654:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5655:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5656:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5657:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5658:    }
                   5659:    for(j=1;j<=cptcoveff;j++) 
                   5660:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5661:    fprintf(ficresprobmorprev,"\n");
                   5662: 
1.218     brouard  5663:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5664:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5665:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5666:      for(i=1; i<=nlstate;i++)
                   5667:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5668:    }  
                   5669:    fprintf(ficresprobmorprev,"\n");
                   5670:   
                   5671:    fprintf(ficgp,"\n# Routine varevsij");
                   5672:    fprintf(ficgp,"\nunset title \n");
                   5673:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5674:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5675:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5676:    /*   } */
                   5677:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5678:    pstamp(ficresvij);
                   5679:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5680:    if(popbased==1)
                   5681:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5682:    else
                   5683:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5684:    fprintf(ficresvij,"# Age");
                   5685:    for(i=1; i<=nlstate;i++)
                   5686:      for(j=1; j<=nlstate;j++)
                   5687:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5688:    fprintf(ficresvij,"\n");
                   5689: 
                   5690:    xp=vector(1,npar);
                   5691:    dnewm=matrix(1,nlstate,1,npar);
                   5692:    doldm=matrix(1,nlstate,1,nlstate);
                   5693:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5694:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5695: 
                   5696:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5697:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5698:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5699:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5700:   
1.218     brouard  5701:    if(estepm < stepm){
                   5702:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5703:    }
                   5704:    else  hstepm=estepm;   
                   5705:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5706:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5707:       nhstepm is the number of hstepm from age to agelim 
                   5708:       nstepm is the number of stepm from age to agelim. 
                   5709:       Look at function hpijx to understand why because of memory size limitations, 
                   5710:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5711:       survival function given by stepm (the optimization length). Unfortunately it
                   5712:       means that if the survival funtion is printed every two years of age and if
                   5713:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5714:       results. So we changed our mind and took the option of the best precision.
                   5715:    */
                   5716:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5717:    agelim = AGESUP;
                   5718:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5719:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5720:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5721:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5722:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5723:      gp=matrix(0,nhstepm,1,nlstate);
                   5724:      gm=matrix(0,nhstepm,1,nlstate);
                   5725:                
                   5726:                
                   5727:      for(theta=1; theta <=npar; theta++){
                   5728:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5729:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5730:        }
                   5731:                        
1.242     brouard  5732:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5733:                        
                   5734:        if (popbased==1) {
                   5735:         if(mobilav ==0){
                   5736:           for(i=1; i<=nlstate;i++)
                   5737:             prlim[i][i]=probs[(int)age][i][ij];
                   5738:         }else{ /* mobilav */ 
                   5739:           for(i=1; i<=nlstate;i++)
                   5740:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5741:         }
                   5742:        }
                   5743:                        
1.235     brouard  5744:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5745:        for(j=1; j<= nlstate; j++){
                   5746:         for(h=0; h<=nhstepm; h++){
                   5747:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5748:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5749:         }
                   5750:        }
                   5751:        /* Next for computing probability of death (h=1 means
                   5752:          computed over hstepm matrices product = hstepm*stepm months) 
                   5753:          as a weighted average of prlim.
                   5754:        */
                   5755:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5756:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5757:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5758:        }    
                   5759:        /* end probability of death */
                   5760:                        
                   5761:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5762:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5763:                        
1.242     brouard  5764:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5765:                        
                   5766:        if (popbased==1) {
                   5767:         if(mobilav ==0){
                   5768:           for(i=1; i<=nlstate;i++)
                   5769:             prlim[i][i]=probs[(int)age][i][ij];
                   5770:         }else{ /* mobilav */ 
                   5771:           for(i=1; i<=nlstate;i++)
                   5772:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5773:         }
                   5774:        }
                   5775:                        
1.235     brouard  5776:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5777:                        
                   5778:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5779:         for(h=0; h<=nhstepm; h++){
                   5780:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5781:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5782:         }
                   5783:        }
                   5784:        /* This for computing probability of death (h=1 means
                   5785:          computed over hstepm matrices product = hstepm*stepm months) 
                   5786:          as a weighted average of prlim.
                   5787:        */
                   5788:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5789:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5790:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5791:        }    
                   5792:        /* end probability of death */
                   5793:                        
                   5794:        for(j=1; j<= nlstate; j++) /* vareij */
                   5795:         for(h=0; h<=nhstepm; h++){
                   5796:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5797:         }
                   5798:                        
                   5799:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5800:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5801:        }
                   5802:                        
                   5803:      } /* End theta */
                   5804:                
                   5805:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5806:                
                   5807:      for(h=0; h<=nhstepm; h++) /* veij */
                   5808:        for(j=1; j<=nlstate;j++)
                   5809:         for(theta=1; theta <=npar; theta++)
                   5810:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5811:                
                   5812:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5813:        for(theta=1; theta <=npar; theta++)
                   5814:         trgradgp[j][theta]=gradgp[theta][j];
                   5815:                
                   5816:                
                   5817:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5818:      for(i=1;i<=nlstate;i++)
                   5819:        for(j=1;j<=nlstate;j++)
                   5820:         vareij[i][j][(int)age] =0.;
                   5821:                
                   5822:      for(h=0;h<=nhstepm;h++){
                   5823:        for(k=0;k<=nhstepm;k++){
                   5824:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5825:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5826:         for(i=1;i<=nlstate;i++)
                   5827:           for(j=1;j<=nlstate;j++)
                   5828:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5829:        }
                   5830:      }
                   5831:                
                   5832:      /* pptj */
                   5833:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5834:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5835:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5836:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5837:         varppt[j][i]=doldmp[j][i];
                   5838:      /* end ppptj */
                   5839:      /*  x centered again */
                   5840:                
1.242     brouard  5841:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5842:                
                   5843:      if (popbased==1) {
                   5844:        if(mobilav ==0){
                   5845:         for(i=1; i<=nlstate;i++)
                   5846:           prlim[i][i]=probs[(int)age][i][ij];
                   5847:        }else{ /* mobilav */ 
                   5848:         for(i=1; i<=nlstate;i++)
                   5849:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5850:        }
                   5851:      }
                   5852:                
                   5853:      /* This for computing probability of death (h=1 means
                   5854:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5855:        as a weighted average of prlim.
                   5856:      */
1.235     brouard  5857:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5858:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5859:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5860:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5861:      }    
                   5862:      /* end probability of death */
                   5863:                
                   5864:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5865:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5866:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5867:        for(i=1; i<=nlstate;i++){
                   5868:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5869:        }
                   5870:      } 
                   5871:      fprintf(ficresprobmorprev,"\n");
                   5872:                
                   5873:      fprintf(ficresvij,"%.0f ",age );
                   5874:      for(i=1; i<=nlstate;i++)
                   5875:        for(j=1; j<=nlstate;j++){
                   5876:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5877:        }
                   5878:      fprintf(ficresvij,"\n");
                   5879:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5880:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5881:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5882:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5883:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5884:    } /* End age */
                   5885:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5886:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5887:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5888:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5889:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5890:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5891:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5892:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5893:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5894:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5895:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5896:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5897:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5898:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5899:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5900:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5901:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5902:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5903:     */
1.218     brouard  5904:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5905:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5906: 
1.218     brouard  5907:    free_vector(xp,1,npar);
                   5908:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5909:    free_matrix(dnewm,1,nlstate,1,npar);
                   5910:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5911:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5912:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5913:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5914:    fclose(ficresprobmorprev);
                   5915:    fflush(ficgp);
                   5916:    fflush(fichtm); 
                   5917:  }  /* end varevsij */
1.126     brouard  5918: 
                   5919: /************ Variance of prevlim ******************/
1.235     brouard  5920:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5921: {
1.205     brouard  5922:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5923:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5924: 
1.126     brouard  5925:   double **dnewm,**doldm;
                   5926:   int i, j, nhstepm, hstepm;
                   5927:   double *xp;
                   5928:   double *gp, *gm;
                   5929:   double **gradg, **trgradg;
1.208     brouard  5930:   double **mgm, **mgp;
1.126     brouard  5931:   double age,agelim;
                   5932:   int theta;
                   5933:   
                   5934:   pstamp(ficresvpl);
                   5935:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5936:   fprintf(ficresvpl,"# Age ");
                   5937:   if(nresult >=1)
                   5938:     fprintf(ficresvpl," Result# ");
1.126     brouard  5939:   for(i=1; i<=nlstate;i++)
                   5940:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5941:   fprintf(ficresvpl,"\n");
                   5942: 
                   5943:   xp=vector(1,npar);
                   5944:   dnewm=matrix(1,nlstate,1,npar);
                   5945:   doldm=matrix(1,nlstate,1,nlstate);
                   5946:   
                   5947:   hstepm=1*YEARM; /* Every year of age */
                   5948:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5949:   agelim = AGESUP;
                   5950:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5951:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5952:     if (stepm >= YEARM) hstepm=1;
                   5953:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5954:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5955:     mgp=matrix(1,npar,1,nlstate);
                   5956:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5957:     gp=vector(1,nlstate);
                   5958:     gm=vector(1,nlstate);
                   5959: 
                   5960:     for(theta=1; theta <=npar; theta++){
                   5961:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5962:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5963:       }
1.209     brouard  5964:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5965:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5966:       else
1.235     brouard  5967:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5968:       for(i=1;i<=nlstate;i++){
1.126     brouard  5969:        gp[i] = prlim[i][i];
1.208     brouard  5970:        mgp[theta][i] = prlim[i][i];
                   5971:       }
1.126     brouard  5972:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5973:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5974:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5975:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5976:       else
1.235     brouard  5977:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5978:       for(i=1;i<=nlstate;i++){
1.126     brouard  5979:        gm[i] = prlim[i][i];
1.208     brouard  5980:        mgm[theta][i] = prlim[i][i];
                   5981:       }
1.126     brouard  5982:       for(i=1;i<=nlstate;i++)
                   5983:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5984:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5985:     } /* End theta */
                   5986: 
                   5987:     trgradg =matrix(1,nlstate,1,npar);
                   5988: 
                   5989:     for(j=1; j<=nlstate;j++)
                   5990:       for(theta=1; theta <=npar; theta++)
                   5991:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5992:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5993:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5994:     /*   for(j=1; j<=nlstate;j++){ */
                   5995:     /*         printf(" %d ",j); */
                   5996:     /*         for(theta=1; theta <=npar; theta++) */
                   5997:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5998:     /*         printf("\n "); */
                   5999:     /*   } */
                   6000:     /* } */
                   6001:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6002:     /*   printf("\n gradg %d ",(int)age); */
                   6003:     /*   for(j=1; j<=nlstate;j++){ */
                   6004:     /*         printf("%d ",j); */
                   6005:     /*         for(theta=1; theta <=npar; theta++) */
                   6006:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6007:     /*         printf("\n "); */
                   6008:     /*   } */
                   6009:     /* } */
1.126     brouard  6010: 
                   6011:     for(i=1;i<=nlstate;i++)
                   6012:       varpl[i][(int)age] =0.;
1.209     brouard  6013:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6014:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6015:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6016:     }else{
1.126     brouard  6017:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6018:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6019:     }
1.126     brouard  6020:     for(i=1;i<=nlstate;i++)
                   6021:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6022: 
                   6023:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6024:     if(nresult >=1)
                   6025:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6026:     for(i=1; i<=nlstate;i++)
                   6027:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6028:     fprintf(ficresvpl,"\n");
                   6029:     free_vector(gp,1,nlstate);
                   6030:     free_vector(gm,1,nlstate);
1.208     brouard  6031:     free_matrix(mgm,1,npar,1,nlstate);
                   6032:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6033:     free_matrix(gradg,1,npar,1,nlstate);
                   6034:     free_matrix(trgradg,1,nlstate,1,npar);
                   6035:   } /* End age */
                   6036: 
                   6037:   free_vector(xp,1,npar);
                   6038:   free_matrix(doldm,1,nlstate,1,npar);
                   6039:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6040: 
                   6041: }
                   6042: 
                   6043: /************ Variance of one-step probabilities  ******************/
                   6044: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6045:  {
                   6046:    int i, j=0,  k1, l1, tj;
                   6047:    int k2, l2, j1,  z1;
                   6048:    int k=0, l;
                   6049:    int first=1, first1, first2;
                   6050:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6051:    double **dnewm,**doldm;
                   6052:    double *xp;
                   6053:    double *gp, *gm;
                   6054:    double **gradg, **trgradg;
                   6055:    double **mu;
                   6056:    double age, cov[NCOVMAX+1];
                   6057:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6058:    int theta;
                   6059:    char fileresprob[FILENAMELENGTH];
                   6060:    char fileresprobcov[FILENAMELENGTH];
                   6061:    char fileresprobcor[FILENAMELENGTH];
                   6062:    double ***varpij;
                   6063: 
                   6064:    strcpy(fileresprob,"PROB_"); 
                   6065:    strcat(fileresprob,fileres);
                   6066:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6067:      printf("Problem with resultfile: %s\n", fileresprob);
                   6068:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6069:    }
                   6070:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6071:    strcat(fileresprobcov,fileresu);
                   6072:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6073:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6074:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6075:    }
                   6076:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6077:    strcat(fileresprobcor,fileresu);
                   6078:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6079:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6080:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6081:    }
                   6082:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6083:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6084:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6085:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6086:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6087:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6088:    pstamp(ficresprob);
                   6089:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6090:    fprintf(ficresprob,"# Age");
                   6091:    pstamp(ficresprobcov);
                   6092:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6093:    fprintf(ficresprobcov,"# Age");
                   6094:    pstamp(ficresprobcor);
                   6095:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6096:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6097: 
                   6098: 
1.222     brouard  6099:    for(i=1; i<=nlstate;i++)
                   6100:      for(j=1; j<=(nlstate+ndeath);j++){
                   6101:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6102:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6103:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6104:      }  
                   6105:    /* fprintf(ficresprob,"\n");
                   6106:       fprintf(ficresprobcov,"\n");
                   6107:       fprintf(ficresprobcor,"\n");
                   6108:    */
                   6109:    xp=vector(1,npar);
                   6110:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6111:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6112:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6113:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6114:    first=1;
                   6115:    fprintf(ficgp,"\n# Routine varprob");
                   6116:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6117:    fprintf(fichtm,"\n");
                   6118: 
                   6119:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6120:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6121:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6122: and drawn. It helps understanding how is the covariance between two incidences.\
                   6123:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6124:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6125: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6126: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6127: standard deviations wide on each axis. <br>\
                   6128:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6129:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6130: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6131: 
1.222     brouard  6132:    cov[1]=1;
                   6133:    /* tj=cptcoveff; */
1.225     brouard  6134:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6135:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6136:    j1=0;
1.224     brouard  6137:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6138:      if  (cptcovn>0) {
                   6139:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6140:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6141:        fprintf(ficresprob, "**********\n#\n");
                   6142:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6143:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6144:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6145:                        
1.222     brouard  6146:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6147:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6148:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6149:                        
                   6150:                        
1.222     brouard  6151:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6152:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6153:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6154:                        
1.222     brouard  6155:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6156:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6157:        fprintf(ficresprobcor, "**********\n#");    
                   6158:        if(invalidvarcomb[j1]){
                   6159:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6160:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6161:         continue;
                   6162:        }
                   6163:      }
                   6164:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6165:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6166:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6167:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6168:      for (age=bage; age<=fage; age ++){ 
                   6169:        cov[2]=age;
                   6170:        if(nagesqr==1)
                   6171:         cov[3]= age*age;
                   6172:        for (k=1; k<=cptcovn;k++) {
                   6173:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6174:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6175:                                                                    * 1  1 1 1 1
                   6176:                                                                    * 2  2 1 1 1
                   6177:                                                                    * 3  1 2 1 1
                   6178:                                                                    */
                   6179:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6180:        }
                   6181:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6182:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6183:        for (k=1; k<=cptcovprod;k++)
                   6184:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6185:                        
                   6186:                        
1.222     brouard  6187:        for(theta=1; theta <=npar; theta++){
                   6188:         for(i=1; i<=npar; i++)
                   6189:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6190:                                
1.222     brouard  6191:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6192:                                
1.222     brouard  6193:         k=0;
                   6194:         for(i=1; i<= (nlstate); i++){
                   6195:           for(j=1; j<=(nlstate+ndeath);j++){
                   6196:             k=k+1;
                   6197:             gp[k]=pmmij[i][j];
                   6198:           }
                   6199:         }
1.220     brouard  6200:                                
1.222     brouard  6201:         for(i=1; i<=npar; i++)
                   6202:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6203:                                
1.222     brouard  6204:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6205:         k=0;
                   6206:         for(i=1; i<=(nlstate); i++){
                   6207:           for(j=1; j<=(nlstate+ndeath);j++){
                   6208:             k=k+1;
                   6209:             gm[k]=pmmij[i][j];
                   6210:           }
                   6211:         }
1.220     brouard  6212:                                
1.222     brouard  6213:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6214:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6215:        }
1.126     brouard  6216: 
1.222     brouard  6217:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6218:         for(theta=1; theta <=npar; theta++)
                   6219:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6220:                        
1.222     brouard  6221:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6222:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6223:                        
1.222     brouard  6224:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6225:                        
1.222     brouard  6226:        k=0;
                   6227:        for(i=1; i<=(nlstate); i++){
                   6228:         for(j=1; j<=(nlstate+ndeath);j++){
                   6229:           k=k+1;
                   6230:           mu[k][(int) age]=pmmij[i][j];
                   6231:         }
                   6232:        }
                   6233:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6234:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6235:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6236:                        
1.222     brouard  6237:        /*printf("\n%d ",(int)age);
                   6238:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6239:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6240:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6241:         }*/
1.220     brouard  6242:                        
1.222     brouard  6243:        fprintf(ficresprob,"\n%d ",(int)age);
                   6244:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6245:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6246:                        
1.222     brouard  6247:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6248:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6249:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6250:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6251:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6252:        }
                   6253:        i=0;
                   6254:        for (k=1; k<=(nlstate);k++){
                   6255:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6256:           i++;
                   6257:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6258:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6259:           for (j=1; j<=i;j++){
                   6260:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6261:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6262:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6263:           }
                   6264:         }
                   6265:        }/* end of loop for state */
                   6266:      } /* end of loop for age */
                   6267:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6268:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6269:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6270:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6271:     
                   6272:      /* Confidence intervalle of pij  */
                   6273:      /*
                   6274:        fprintf(ficgp,"\nunset parametric;unset label");
                   6275:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6276:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6277:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6278:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6279:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6280:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6281:      */
                   6282:                
                   6283:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6284:      first1=1;first2=2;
                   6285:      for (k2=1; k2<=(nlstate);k2++){
                   6286:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6287:         if(l2==k2) continue;
                   6288:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6289:         for (k1=1; k1<=(nlstate);k1++){
                   6290:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6291:             if(l1==k1) continue;
                   6292:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6293:             if(i<=j) continue;
                   6294:             for (age=bage; age<=fage; age ++){ 
                   6295:               if ((int)age %5==0){
                   6296:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6297:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6298:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6299:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6300:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6301:                 c12=cv12/sqrt(v1*v2);
                   6302:                 /* Computing eigen value of matrix of covariance */
                   6303:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6304:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6305:                 if ((lc2 <0) || (lc1 <0) ){
                   6306:                   if(first2==1){
                   6307:                     first1=0;
                   6308:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6309:                   }
                   6310:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6311:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6312:                   /* lc2=fabs(lc2); */
                   6313:                 }
1.220     brouard  6314:                                                                
1.222     brouard  6315:                 /* Eigen vectors */
                   6316:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6317:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6318:                 v21=(lc1-v1)/cv12*v11;
                   6319:                 v12=-v21;
                   6320:                 v22=v11;
                   6321:                 tnalp=v21/v11;
                   6322:                 if(first1==1){
                   6323:                   first1=0;
                   6324:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6325:                 }
                   6326:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6327:                 /*printf(fignu*/
                   6328:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6329:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6330:                 if(first==1){
                   6331:                   first=0;
                   6332:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6333:                   fprintf(ficgp,"\nset parametric;unset label");
                   6334:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6335:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6336:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6337:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6338: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6339:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6340:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6341:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6342:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6343:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6344:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6345:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6346:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6347:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6348:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6349:                 }else{
                   6350:                   first=0;
                   6351:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6352:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6353:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6354:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6355:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6356:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6357:                 }/* if first */
                   6358:               } /* age mod 5 */
                   6359:             } /* end loop age */
                   6360:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6361:             first=1;
                   6362:           } /*l12 */
                   6363:         } /* k12 */
                   6364:        } /*l1 */
                   6365:      }/* k1 */
                   6366:    }  /* loop on combination of covariates j1 */
                   6367:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6368:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6369:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6370:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6371:    free_vector(xp,1,npar);
                   6372:    fclose(ficresprob);
                   6373:    fclose(ficresprobcov);
                   6374:    fclose(ficresprobcor);
                   6375:    fflush(ficgp);
                   6376:    fflush(fichtmcov);
                   6377:  }
1.126     brouard  6378: 
                   6379: 
                   6380: /******************* Printing html file ***********/
1.201     brouard  6381: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6382:                  int lastpass, int stepm, int weightopt, char model[],\
                   6383:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6384:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6385:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6386:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6387:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6388: 
                   6389:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6390:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6391: </ul>");
1.237     brouard  6392:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6393: </ul>", model);
1.214     brouard  6394:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6395:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6396:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6397:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6398:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6399:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6400:    fprintf(fichtm,"\
                   6401:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6402:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6403:    fprintf(fichtm,"\
1.217     brouard  6404:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6405:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6406:    fprintf(fichtm,"\
1.126     brouard  6407:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6408:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6409:    fprintf(fichtm,"\
1.217     brouard  6410:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6411:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6412:    fprintf(fichtm,"\
1.211     brouard  6413:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6414:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6415:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6416:    if(prevfcast==1){
                   6417:      fprintf(fichtm,"\
                   6418:  - Prevalence projections by age and states:                           \
1.201     brouard  6419:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6420:    }
1.126     brouard  6421: 
1.222     brouard  6422:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6423: 
1.225     brouard  6424:    m=pow(2,cptcoveff);
1.222     brouard  6425:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6426: 
1.222     brouard  6427:    jj1=0;
1.237     brouard  6428: 
                   6429:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6430:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6431:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6432:        continue;
1.220     brouard  6433: 
1.222     brouard  6434:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6435:      jj1++;
                   6436:      if (cptcovn > 0) {
                   6437:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6438:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6439:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6440:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6441:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6442:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6443:        }
1.237     brouard  6444:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6445:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6446:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6447:       }
                   6448:        
1.230     brouard  6449:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6450:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6451:        if(invalidvarcomb[k1]){
                   6452:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6453:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6454:         continue;
                   6455:        }
                   6456:      }
                   6457:      /* aij, bij */
1.259   ! brouard  6458:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6459: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6460:      /* Pij */
1.241     brouard  6461:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6462: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6463:      /* Quasi-incidences */
                   6464:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6465:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6466:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6467: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6468: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6469:      /* Survival functions (period) in state j */
                   6470:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6471:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6472: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6473:      }
                   6474:      /* State specific survival functions (period) */
                   6475:      for(cpt=1; cpt<=nlstate;cpt++){
                   6476:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6477:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6478:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6479:      }
                   6480:      /* Period (stable) prevalence in each health state */
                   6481:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6482:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6483: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6484:      }
                   6485:      if(backcast==1){
                   6486:        /* Period (stable) back prevalence in each health state */
                   6487:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6488:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6489: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6490:        }
1.217     brouard  6491:      }
1.222     brouard  6492:      if(prevfcast==1){
                   6493:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6494:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6495:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6496: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6497:        }
                   6498:      }
1.220     brouard  6499:         
1.222     brouard  6500:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6501:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6502: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6503:      }
                   6504:      /* } /\* end i1 *\/ */
                   6505:    }/* End k1 */
                   6506:    fprintf(fichtm,"</ul>");
1.126     brouard  6507: 
1.222     brouard  6508:    fprintf(fichtm,"\
1.126     brouard  6509: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6510:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6511:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6512: But because parameters are usually highly correlated (a higher incidence of disability \
                   6513: and a higher incidence of recovery can give very close observed transition) it might \
                   6514: be very useful to look not only at linear confidence intervals estimated from the \
                   6515: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6516: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6517: covariance matrix of the one-step probabilities. \
                   6518: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6519: 
1.222     brouard  6520:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6521:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6522:    fprintf(fichtm,"\
1.126     brouard  6523:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6524:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6525: 
1.222     brouard  6526:    fprintf(fichtm,"\
1.126     brouard  6527:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6528:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6529:    fprintf(fichtm,"\
1.126     brouard  6530:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6531:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6532:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6533:    fprintf(fichtm,"\
1.126     brouard  6534:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6535:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6536:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6537:    fprintf(fichtm,"\
1.128     brouard  6538:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6539:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6540:    fprintf(fichtm,"\
1.128     brouard  6541:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6542:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6543:    fprintf(fichtm,"\
1.126     brouard  6544:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6545:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6546: 
                   6547: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6548: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6549: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6550: /*     <br>",fileres,fileres,fileres,fileres); */
                   6551: /*  else  */
                   6552: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6553:    fflush(fichtm);
                   6554:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6555: 
1.225     brouard  6556:    m=pow(2,cptcoveff);
1.222     brouard  6557:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6558: 
1.222     brouard  6559:    jj1=0;
1.237     brouard  6560: 
1.241     brouard  6561:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6562:    for(k1=1; k1<=m;k1++){
1.253     brouard  6563:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6564:        continue;
1.222     brouard  6565:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6566:      jj1++;
1.126     brouard  6567:      if (cptcovn > 0) {
                   6568:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6569:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6570:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6571:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6572:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6573:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6574:       }
                   6575: 
1.126     brouard  6576:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6577: 
1.222     brouard  6578:        if(invalidvarcomb[k1]){
                   6579:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6580:         continue;
                   6581:        }
1.126     brouard  6582:      }
                   6583:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6584:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6585: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6586: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6587:      }
                   6588:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6589: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6590: true period expectancies (those weighted with period prevalences are also\
                   6591:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6592:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6593: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6594:      /* } /\* end i1 *\/ */
                   6595:    }/* End k1 */
1.241     brouard  6596:   }/* End nres */
1.222     brouard  6597:    fprintf(fichtm,"</ul>");
                   6598:    fflush(fichtm);
1.126     brouard  6599: }
                   6600: 
                   6601: /******************* Gnuplot file **************/
1.223     brouard  6602: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6603: 
                   6604:   char dirfileres[132],optfileres[132];
1.223     brouard  6605:   char gplotcondition[132];
1.237     brouard  6606:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6607:   int lv=0, vlv=0, kl=0;
1.130     brouard  6608:   int ng=0;
1.201     brouard  6609:   int vpopbased;
1.223     brouard  6610:   int ioffset; /* variable offset for columns */
1.235     brouard  6611:   int nres=0; /* Index of resultline */
1.219     brouard  6612: 
1.126     brouard  6613: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6614: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6615: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6616: /*   } */
                   6617: 
                   6618:   /*#ifdef windows */
                   6619:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6620:   /*#endif */
1.225     brouard  6621:   m=pow(2,cptcoveff);
1.126     brouard  6622: 
1.202     brouard  6623:   /* Contribution to likelihood */
                   6624:   /* Plot the probability implied in the likelihood */
1.223     brouard  6625:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6626:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6627:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6628:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6629: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6630:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6631: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6632:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6633:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6634:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6635:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6636:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6637:   for (i=1; i<= nlstate ; i ++) {
                   6638:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6639:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6640:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6641:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6642:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6643:     }
                   6644:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6645:   }
                   6646:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6647:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6648:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6649:   fprintf(ficgp,"\nset out;unset log\n");
                   6650:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6651: 
1.126     brouard  6652:   strcpy(dirfileres,optionfilefiname);
                   6653:   strcpy(optfileres,"vpl");
1.223     brouard  6654:   /* 1eme*/
1.238     brouard  6655:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6656:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6657:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6658:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6659:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6660:          continue;
                   6661:        /* We are interested in selected combination by the resultline */
1.246     brouard  6662:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6663:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6664:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6665:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6666:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6667:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6668:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6669:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6670:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6671:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6672:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6673:        }
                   6674:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6675:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6676:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6677:        }       
1.246     brouard  6678:        /* printf("\n#\n"); */
1.238     brouard  6679:        fprintf(ficgp,"\n#\n");
                   6680:        if(invalidvarcomb[k1]){
                   6681:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6682:          continue;
                   6683:        }
1.235     brouard  6684:       
1.241     brouard  6685:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6686:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6687:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6688:       
1.238     brouard  6689:        for (i=1; i<= nlstate ; i ++) {
                   6690:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6691:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6692:        }
1.242     brouard  6693:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6694:        for (i=1; i<= nlstate ; i ++) {
                   6695:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6696:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6697:        } 
1.242     brouard  6698:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6699:        for (i=1; i<= nlstate ; i ++) {
                   6700:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6701:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6702:        }  
                   6703:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6704:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6705:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6706:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6707:          if(cptcoveff ==0){
1.245     brouard  6708:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6709:          }else{
                   6710:            kl=0;
                   6711:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6712:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6713:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6714:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6715:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6716:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6717:              kl++;
1.238     brouard  6718:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6719:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6720:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6721:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6722:              if(k==cptcoveff){
1.245     brouard  6723:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6724:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6725:              }else{
                   6726:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6727:                kl++;
                   6728:              }
                   6729:            } /* end covariate */
                   6730:          } /* end if no covariate */
                   6731:        } /* end if backcast */
                   6732:        fprintf(ficgp,"\nset out \n");
                   6733:       } /* nres */
1.201     brouard  6734:     } /* k1 */
                   6735:   } /* cpt */
1.235     brouard  6736: 
                   6737:   
1.126     brouard  6738:   /*2 eme*/
1.238     brouard  6739:   for (k1=1; k1<= m ; k1 ++){  
                   6740:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6741:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6742:        continue;
                   6743:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6744:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6745:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6746:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6747:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6748:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6749:        vlv= nbcode[Tvaraff[k]][lv];
                   6750:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6751:       }
1.237     brouard  6752:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6753:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6754:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6755:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6756:       }
1.211     brouard  6757:       fprintf(ficgp,"\n#\n");
1.223     brouard  6758:       if(invalidvarcomb[k1]){
                   6759:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6760:        continue;
                   6761:       }
1.219     brouard  6762:                        
1.241     brouard  6763:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6764:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6765:        if(vpopbased==0)
                   6766:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6767:        else
                   6768:          fprintf(ficgp,"\nreplot ");
                   6769:        for (i=1; i<= nlstate+1 ; i ++) {
                   6770:          k=2*i;
                   6771:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6772:          for (j=1; j<= nlstate+1 ; j ++) {
                   6773:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6774:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6775:          }   
                   6776:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6777:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6778:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6779:          for (j=1; j<= nlstate+1 ; j ++) {
                   6780:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6781:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6782:          }   
                   6783:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6784:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6785:          for (j=1; j<= nlstate+1 ; j ++) {
                   6786:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6787:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6788:          }   
                   6789:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6790:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6791:        } /* state */
                   6792:       } /* vpopbased */
1.244     brouard  6793:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6794:     } /* end nres */
                   6795:   } /* k1 end 2 eme*/
                   6796:        
                   6797:        
                   6798:   /*3eme*/
                   6799:   for (k1=1; k1<= m ; k1 ++){
                   6800:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6801:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6802:        continue;
                   6803: 
                   6804:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6805:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6806:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6807:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6808:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6809:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6810:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6811:          vlv= nbcode[Tvaraff[k]][lv];
                   6812:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6813:        }
                   6814:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6815:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6816:        }       
                   6817:        fprintf(ficgp,"\n#\n");
                   6818:        if(invalidvarcomb[k1]){
                   6819:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6820:          continue;
                   6821:        }
                   6822:                        
                   6823:        /*       k=2+nlstate*(2*cpt-2); */
                   6824:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6825:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6826:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6827: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6828:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6829:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6830:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6831:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6832:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6833:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6834:                                
1.238     brouard  6835:        */
                   6836:        for (i=1; i< nlstate ; i ++) {
                   6837:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6838:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6839:                                
1.238     brouard  6840:        } 
                   6841:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6842:       }
                   6843:     } /* end nres */
                   6844:   } /* end kl 3eme */
1.126     brouard  6845:   
1.223     brouard  6846:   /* 4eme */
1.201     brouard  6847:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6848:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6849:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6850:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6851:        continue;
1.238     brouard  6852:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6853:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6854:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6855:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6856:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6857:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6858:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6859:          vlv= nbcode[Tvaraff[k]][lv];
                   6860:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6861:        }
                   6862:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6863:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6864:        }       
                   6865:        fprintf(ficgp,"\n#\n");
                   6866:        if(invalidvarcomb[k1]){
                   6867:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6868:          continue;
1.223     brouard  6869:        }
1.238     brouard  6870:       
1.241     brouard  6871:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6872:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6873: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6874:        k=3;
                   6875:        for (i=1; i<= nlstate ; i ++){
                   6876:          if(i==1){
                   6877:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6878:          }else{
                   6879:            fprintf(ficgp,", '' ");
                   6880:          }
                   6881:          l=(nlstate+ndeath)*(i-1)+1;
                   6882:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6883:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6884:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6885:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6886:        } /* nlstate */
                   6887:        fprintf(ficgp,"\nset out\n");
                   6888:       } /* end cpt state*/ 
                   6889:     } /* end nres */
                   6890:   } /* end covariate k1 */  
                   6891: 
1.220     brouard  6892: /* 5eme */
1.201     brouard  6893:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6894:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6895:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6896:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6897:        continue;
1.238     brouard  6898:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6899:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6900:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6901:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6902:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6903:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6904:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6905:          vlv= nbcode[Tvaraff[k]][lv];
                   6906:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6907:        }
                   6908:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6909:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6910:        }       
                   6911:        fprintf(ficgp,"\n#\n");
                   6912:        if(invalidvarcomb[k1]){
                   6913:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6914:          continue;
                   6915:        }
1.227     brouard  6916:       
1.241     brouard  6917:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6918:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6919: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6920:        k=3;
                   6921:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6922:          if(j==1)
                   6923:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6924:          else
                   6925:            fprintf(ficgp,", '' ");
                   6926:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6927:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6928:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6929:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6930:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6931:        } /* nlstate */
                   6932:        fprintf(ficgp,", '' ");
                   6933:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6934:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6935:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6936:          if(j < nlstate)
                   6937:            fprintf(ficgp,"$%d +",k+l);
                   6938:          else
                   6939:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6940:        }
                   6941:        fprintf(ficgp,"\nset out\n");
                   6942:       } /* end cpt state*/ 
                   6943:     } /* end covariate */  
                   6944:   } /* end nres */
1.227     brouard  6945:   
1.220     brouard  6946: /* 6eme */
1.202     brouard  6947:   /* CV preval stable (period) for each covariate */
1.237     brouard  6948:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6949:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6950:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6951:       continue;
1.255     brouard  6952:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6953:       
1.211     brouard  6954:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6955:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6956:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6957:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6958:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6959:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6960:        vlv= nbcode[Tvaraff[k]][lv];
                   6961:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6962:       }
1.237     brouard  6963:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6964:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6965:       }        
1.211     brouard  6966:       fprintf(ficgp,"\n#\n");
1.223     brouard  6967:       if(invalidvarcomb[k1]){
1.227     brouard  6968:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6969:        continue;
1.223     brouard  6970:       }
1.227     brouard  6971:       
1.241     brouard  6972:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6973:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6974: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6975:       k=3; /* Offset */
1.255     brouard  6976:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6977:        if(i==1)
                   6978:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6979:        else
                   6980:          fprintf(ficgp,", '' ");
1.255     brouard  6981:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6982:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6983:        for (j=2; j<= nlstate ; j ++)
                   6984:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6985:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6986:       } /* nlstate */
1.201     brouard  6987:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6988:     } /* end cpt state*/ 
                   6989:   } /* end covariate */  
1.227     brouard  6990:   
                   6991:   
1.220     brouard  6992: /* 7eme */
1.218     brouard  6993:   if(backcast == 1){
1.217     brouard  6994:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6995:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6996:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6997:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6998:        continue;
1.255     brouard  6999:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   7000:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7001:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7002:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7003:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7004:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7005:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7006:          vlv= nbcode[Tvaraff[k]][lv];
                   7007:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7008:        }
1.237     brouard  7009:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7010:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7011:        }       
1.227     brouard  7012:        fprintf(ficgp,"\n#\n");
                   7013:        if(invalidvarcomb[k1]){
                   7014:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7015:          continue;
                   7016:        }
                   7017:        
1.241     brouard  7018:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7019:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7020: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7021:        k=3; /* Offset */
1.255     brouard  7022:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7023:          if(i==1)
                   7024:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7025:          else
                   7026:            fprintf(ficgp,", '' ");
                   7027:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7028:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7029:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7030:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7031:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7032:          /* for (j=2; j<= nlstate ; j ++) */
                   7033:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7034:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7035:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7036:        } /* nlstate */
                   7037:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7038:       } /* end cpt state*/ 
                   7039:     } /* end covariate */  
                   7040:   } /* End if backcast */
                   7041:   
1.223     brouard  7042:   /* 8eme */
1.218     brouard  7043:   if(prevfcast==1){
                   7044:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7045:     
1.237     brouard  7046:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7047:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7048:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7049:        continue;
1.211     brouard  7050:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7051:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7052:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7053:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7054:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7055:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7056:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7057:          vlv= nbcode[Tvaraff[k]][lv];
                   7058:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7059:        }
1.237     brouard  7060:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7061:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7062:        }       
1.227     brouard  7063:        fprintf(ficgp,"\n#\n");
                   7064:        if(invalidvarcomb[k1]){
                   7065:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7066:          continue;
                   7067:        }
                   7068:        
                   7069:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7070:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7071:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7072: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7073:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7074:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7075:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7076:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7077:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7078:          if(i==1){
                   7079:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7080:          }else{
                   7081:            fprintf(ficgp,",\\\n '' ");
                   7082:          }
                   7083:          if(cptcoveff ==0){ /* No covariate */
                   7084:            ioffset=2; /* Age is in 2 */
                   7085:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7086:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7087:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7088:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7089:            fprintf(ficgp," u %d:(", ioffset); 
                   7090:            if(i==nlstate+1)
                   7091:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7092:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7093:            else
                   7094:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7095:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7096:          }else{ /* more than 2 covariates */
                   7097:            if(cptcoveff ==1){
                   7098:              ioffset=4; /* Age is in 4 */
                   7099:            }else{
                   7100:              ioffset=6; /* Age is in 6 */
                   7101:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7102:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7103:            }   
                   7104:            fprintf(ficgp," u %d:(",ioffset); 
                   7105:            kl=0;
                   7106:            strcpy(gplotcondition,"(");
                   7107:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7108:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7109:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7110:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7111:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7112:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7113:              kl++;
                   7114:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7115:              kl++;
                   7116:              if(k <cptcoveff && cptcoveff>1)
                   7117:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7118:            }
                   7119:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7120:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7121:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7122:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7123:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7124:            if(i==nlstate+1){
                   7125:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7126:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7127:            }else{
                   7128:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7129:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7130:            }
                   7131:          } /* end if covariate */
                   7132:        } /* nlstate */
                   7133:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7134:       } /* end cpt state*/
                   7135:     } /* end covariate */
                   7136:   } /* End if prevfcast */
1.227     brouard  7137:   
                   7138:   
1.238     brouard  7139:   /* 9eme writing MLE parameters */
                   7140:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7141:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7142:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7143:     for(k=1; k <=(nlstate+ndeath); k++){
                   7144:       if (k != i) {
1.227     brouard  7145:        fprintf(ficgp,"#   current state %d\n",k);
                   7146:        for(j=1; j <=ncovmodel; j++){
                   7147:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7148:          jk++; 
                   7149:        }
                   7150:        fprintf(ficgp,"\n");
1.126     brouard  7151:       }
                   7152:     }
1.223     brouard  7153:   }
1.187     brouard  7154:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7155:   
1.145     brouard  7156:   /*goto avoid;*/
1.238     brouard  7157:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7158:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7159:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7160:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7161:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7162:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7163:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7164:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7165:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7166:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7167:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7168:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7169:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7170:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7171:   fprintf(ficgp,"#\n");
1.223     brouard  7172:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7173:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7174:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7175:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7176:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7177:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7178:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7179:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7180:        continue;
                   7181:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7182:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7183:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7184:       }        
                   7185:       fprintf(ficgp,"\n#\n");
1.241     brouard  7186:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7187:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7188:       if (ng==1){
                   7189:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7190:        fprintf(ficgp,"\nunset log y");
                   7191:       }else if (ng==2){
                   7192:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7193:        fprintf(ficgp,"\nset log y");
                   7194:       }else if (ng==3){
                   7195:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7196:        fprintf(ficgp,"\nset log y");
                   7197:       }else
                   7198:        fprintf(ficgp,"\nunset title ");
                   7199:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7200:       i=1;
                   7201:       for(k2=1; k2<=nlstate; k2++) {
                   7202:        k3=i;
                   7203:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7204:          if (k != k2){
                   7205:            switch( ng) {
                   7206:            case 1:
                   7207:              if(nagesqr==0)
                   7208:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7209:              else /* nagesqr =1 */
                   7210:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7211:              break;
                   7212:            case 2: /* ng=2 */
                   7213:              if(nagesqr==0)
                   7214:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7215:              else /* nagesqr =1 */
                   7216:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7217:              break;
                   7218:            case 3:
                   7219:              if(nagesqr==0)
                   7220:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7221:              else /* nagesqr =1 */
                   7222:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7223:              break;
                   7224:            }
                   7225:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7226:            ijp=1; /* product no age */
                   7227:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7228:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7229:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7230:              if(j==Tage[ij]) { /* Product by age */
                   7231:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7232:                  if(DummyV[j]==0){
1.237     brouard  7233:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7234:                  }else{ /* quantitative */
                   7235:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7236:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7237:                  }
                   7238:                  ij++;
                   7239:                }
                   7240:              }else if(j==Tprod[ijp]) { /* */ 
                   7241:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7242:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7243:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7244:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7245:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7246:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7247:                    }else{ /* Vn is dummy and Vm is quanti */
                   7248:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7249:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7250:                    }
                   7251:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7252:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7253:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7254:                    }else{ /* Both quanti */
                   7255:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7256:                    }
                   7257:                  }
1.238     brouard  7258:                  ijp++;
1.237     brouard  7259:                }
                   7260:              } else{  /* simple covariate */
                   7261:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7262:                if(Dummy[j]==0){
                   7263:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7264:                }else{ /* quantitative */
                   7265:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7266:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7267:                }
1.237     brouard  7268:              } /* end simple */
                   7269:            } /* end j */
1.223     brouard  7270:          }else{
                   7271:            i=i-ncovmodel;
                   7272:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7273:              fprintf(ficgp," (1.");
                   7274:          }
1.227     brouard  7275:          
1.223     brouard  7276:          if(ng != 1){
                   7277:            fprintf(ficgp,")/(1");
1.227     brouard  7278:            
1.223     brouard  7279:            for(k1=1; k1 <=nlstate; k1++){ 
                   7280:              if(nagesqr==0)
                   7281:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7282:              else /* nagesqr =1 */
                   7283:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7284:               
1.223     brouard  7285:              ij=1;
                   7286:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7287:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7288:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7289:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7290:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7291:                    ij++;
                   7292:                  }
                   7293:                }
                   7294:                else
1.225     brouard  7295:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7296:              }
                   7297:              fprintf(ficgp,")");
                   7298:            }
                   7299:            fprintf(ficgp,")");
                   7300:            if(ng ==2)
                   7301:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7302:            else /* ng= 3 */
                   7303:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7304:          }else{ /* end ng <> 1 */
                   7305:            if( k !=k2) /* logit p11 is hard to draw */
                   7306:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7307:          }
                   7308:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7309:            fprintf(ficgp,",");
                   7310:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7311:            fprintf(ficgp,",");
                   7312:          i=i+ncovmodel;
                   7313:        } /* end k */
                   7314:       } /* end k2 */
                   7315:       fprintf(ficgp,"\n set out\n");
                   7316:     } /* end jk */
                   7317:   } /* end ng */
                   7318:   /* avoid: */
                   7319:   fflush(ficgp); 
1.126     brouard  7320: }  /* end gnuplot */
                   7321: 
                   7322: 
                   7323: /*************** Moving average **************/
1.219     brouard  7324: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7325:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7326:    
1.222     brouard  7327:    int i, cpt, cptcod;
                   7328:    int modcovmax =1;
                   7329:    int mobilavrange, mob;
                   7330:    int iage=0;
                   7331: 
                   7332:    double sum=0.;
                   7333:    double age;
                   7334:    double *sumnewp, *sumnewm;
                   7335:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7336:   
                   7337:   
1.225     brouard  7338:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7339:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7340: 
                   7341:    sumnewp = vector(1,ncovcombmax);
                   7342:    sumnewm = vector(1,ncovcombmax);
                   7343:    agemingood = vector(1,ncovcombmax); 
                   7344:    agemaxgood = vector(1,ncovcombmax);
                   7345: 
                   7346:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7347:      sumnewm[cptcod]=0.;
                   7348:      sumnewp[cptcod]=0.;
                   7349:      agemingood[cptcod]=0;
                   7350:      agemaxgood[cptcod]=0;
                   7351:    }
                   7352:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7353:   
                   7354:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7355:      if(mobilav==1) mobilavrange=5; /* default */
                   7356:      else mobilavrange=mobilav;
                   7357:      for (age=bage; age<=fage; age++)
                   7358:        for (i=1; i<=nlstate;i++)
                   7359:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7360:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7361:      /* We keep the original values on the extreme ages bage, fage and for 
                   7362:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7363:        we use a 5 terms etc. until the borders are no more concerned. 
                   7364:      */ 
                   7365:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7366:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7367:         for (i=1; i<=nlstate;i++){
                   7368:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7369:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7370:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7371:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7372:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7373:             }
                   7374:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7375:           }
                   7376:         }
                   7377:        }/* end age */
                   7378:      }/* end mob */
                   7379:    }else
                   7380:      return -1;
                   7381:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7382:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7383:      if(invalidvarcomb[cptcod]){
                   7384:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7385:        continue;
                   7386:      }
1.219     brouard  7387: 
1.222     brouard  7388:      agemingood[cptcod]=fage-(mob-1)/2;
                   7389:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7390:        sumnewm[cptcod]=0.;
                   7391:        for (i=1; i<=nlstate;i++){
                   7392:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7393:        }
                   7394:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7395:         agemingood[cptcod]=age;
                   7396:        }else{ /* bad */
                   7397:         for (i=1; i<=nlstate;i++){
                   7398:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7399:         } /* i */
                   7400:        } /* end bad */
                   7401:      }/* age */
                   7402:      sum=0.;
                   7403:      for (i=1; i<=nlstate;i++){
                   7404:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7405:      }
                   7406:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7407:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7408:        /* for (i=1; i<=nlstate;i++){ */
                   7409:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7410:        /* } /\* i *\/ */
                   7411:      } /* end bad */
                   7412:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7413:      /* From youngest, finding the oldest wrong */
                   7414:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7415:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7416:        sumnewm[cptcod]=0.;
                   7417:        for (i=1; i<=nlstate;i++){
                   7418:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7419:        }
                   7420:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7421:         agemaxgood[cptcod]=age;
                   7422:        }else{ /* bad */
                   7423:         for (i=1; i<=nlstate;i++){
                   7424:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7425:         } /* i */
                   7426:        } /* end bad */
                   7427:      }/* age */
                   7428:      sum=0.;
                   7429:      for (i=1; i<=nlstate;i++){
                   7430:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7431:      }
                   7432:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7433:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7434:        /* for (i=1; i<=nlstate;i++){ */
                   7435:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7436:        /* } /\* i *\/ */
                   7437:      } /* end bad */
                   7438:                
                   7439:      for (age=bage; age<=fage; age++){
1.235     brouard  7440:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7441:        sumnewp[cptcod]=0.;
                   7442:        sumnewm[cptcod]=0.;
                   7443:        for (i=1; i<=nlstate;i++){
                   7444:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7445:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7446:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7447:        }
                   7448:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7449:      }
                   7450:      /* printf("\n"); */
                   7451:      /* } */
                   7452:      /* brutal averaging */
                   7453:      for (i=1; i<=nlstate;i++){
                   7454:        for (age=1; age<=bage; age++){
                   7455:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7456:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7457:        }       
                   7458:        for (age=fage; age<=AGESUP; age++){
                   7459:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7460:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7461:        }
                   7462:      } /* end i status */
                   7463:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7464:        for (age=1; age<=AGESUP; age++){
                   7465:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7466:         mobaverage[(int)age][i][cptcod]=0.;
                   7467:        }
                   7468:      }
                   7469:    }/* end cptcod */
                   7470:    free_vector(sumnewm,1, ncovcombmax);
                   7471:    free_vector(sumnewp,1, ncovcombmax);
                   7472:    free_vector(agemaxgood,1, ncovcombmax);
                   7473:    free_vector(agemingood,1, ncovcombmax);
                   7474:    return 0;
                   7475:  }/* End movingaverage */
1.218     brouard  7476:  
1.126     brouard  7477: 
                   7478: /************** Forecasting ******************/
1.235     brouard  7479:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7480:   /* proj1, year, month, day of starting projection 
                   7481:      agemin, agemax range of age
                   7482:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7483:      anproj2 year of en of projection (same day and month as proj1).
                   7484:   */
1.235     brouard  7485:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7486:   double agec; /* generic age */
                   7487:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7488:   double *popeffectif,*popcount;
                   7489:   double ***p3mat;
1.218     brouard  7490:   /* double ***mobaverage; */
1.126     brouard  7491:   char fileresf[FILENAMELENGTH];
                   7492: 
                   7493:   agelim=AGESUP;
1.211     brouard  7494:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7495:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7496:      We still use firstpass and lastpass as another selection.
                   7497:   */
1.214     brouard  7498:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7499:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7500:  
1.201     brouard  7501:   strcpy(fileresf,"F_"); 
                   7502:   strcat(fileresf,fileresu);
1.126     brouard  7503:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7504:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7505:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7506:   }
1.235     brouard  7507:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7508:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7509: 
1.225     brouard  7510:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7511: 
                   7512: 
                   7513:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7514:   if (stepm<=12) stepsize=1;
                   7515:   if(estepm < stepm){
                   7516:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7517:   }
                   7518:   else  hstepm=estepm;   
                   7519: 
                   7520:   hstepm=hstepm/stepm; 
                   7521:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7522:                                fractional in yp1 */
                   7523:   anprojmean=yp;
                   7524:   yp2=modf((yp1*12),&yp);
                   7525:   mprojmean=yp;
                   7526:   yp1=modf((yp2*30.5),&yp);
                   7527:   jprojmean=yp;
                   7528:   if(jprojmean==0) jprojmean=1;
                   7529:   if(mprojmean==0) jprojmean=1;
                   7530: 
1.227     brouard  7531:   i1=pow(2,cptcoveff);
1.126     brouard  7532:   if (cptcovn < 1){i1=1;}
                   7533:   
                   7534:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7535:   
                   7536:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7537:   
1.126     brouard  7538: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7539:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7540:   for(k=1; k<=i1;k++){
1.253     brouard  7541:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7542:       continue;
1.227     brouard  7543:     if(invalidvarcomb[k]){
                   7544:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7545:       continue;
                   7546:     }
                   7547:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7548:     for(j=1;j<=cptcoveff;j++) {
                   7549:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7550:     }
1.235     brouard  7551:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7552:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7553:     }
1.227     brouard  7554:     fprintf(ficresf," yearproj age");
                   7555:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7556:       for(i=1; i<=nlstate;i++)               
                   7557:        fprintf(ficresf," p%d%d",i,j);
                   7558:       fprintf(ficresf," wp.%d",j);
                   7559:     }
                   7560:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7561:       fprintf(ficresf,"\n");
                   7562:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7563:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7564:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7565:        nhstepm = nhstepm/hstepm; 
                   7566:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7567:        oldm=oldms;savm=savms;
1.235     brouard  7568:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7569:        
                   7570:        for (h=0; h<=nhstepm; h++){
                   7571:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7572:            fprintf(ficresf,"\n");
                   7573:            for(j=1;j<=cptcoveff;j++) 
                   7574:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7575:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7576:          } 
                   7577:          for(j=1; j<=nlstate+ndeath;j++) {
                   7578:            ppij=0.;
                   7579:            for(i=1; i<=nlstate;i++) {
                   7580:              if (mobilav==1) 
                   7581:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7582:              else {
                   7583:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7584:              }
                   7585:              if (h*hstepm/YEARM*stepm== yearp) {
                   7586:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7587:              }
                   7588:            } /* end i */
                   7589:            if (h*hstepm/YEARM*stepm==yearp) {
                   7590:              fprintf(ficresf," %.3f", ppij);
                   7591:            }
                   7592:          }/* end j */
                   7593:        } /* end h */
                   7594:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7595:       } /* end agec */
                   7596:     } /* end yearp */
                   7597:   } /* end  k */
1.219     brouard  7598:        
1.126     brouard  7599:   fclose(ficresf);
1.215     brouard  7600:   printf("End of Computing forecasting \n");
                   7601:   fprintf(ficlog,"End of Computing forecasting\n");
                   7602: 
1.126     brouard  7603: }
                   7604: 
1.218     brouard  7605: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7606: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7607: /*   /\* back1, year, month, day of starting backection  */
                   7608: /*      agemin, agemax range of age */
                   7609: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7610: /*      anback2 year of en of backection (same day and month as back1). */
                   7611: /*   *\/ */
                   7612: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7613: /*   double agec; /\* generic age *\/ */
                   7614: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7615: /*   double *popeffectif,*popcount; */
                   7616: /*   double ***p3mat; */
                   7617: /*   /\* double ***mobaverage; *\/ */
                   7618: /*   char fileresfb[FILENAMELENGTH]; */
                   7619:        
                   7620: /*   agelim=AGESUP; */
                   7621: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7622: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7623: /*      We still use firstpass and lastpass as another selection. */
                   7624: /*   *\/ */
                   7625: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7626: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7627: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7628:        
                   7629: /*   strcpy(fileresfb,"FB_");  */
                   7630: /*   strcat(fileresfb,fileresu); */
                   7631: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7632: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7633: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7634: /*   } */
                   7635: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7636: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7637:        
1.225     brouard  7638: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7639:        
                   7640: /*   /\* if (mobilav!=0) { *\/ */
                   7641: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7642: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7643: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7644: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7645: /*   /\*   } *\/ */
                   7646: /*   /\* } *\/ */
                   7647:        
                   7648: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7649: /*   if (stepm<=12) stepsize=1; */
                   7650: /*   if(estepm < stepm){ */
                   7651: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7652: /*   } */
                   7653: /*   else  hstepm=estepm;    */
                   7654:        
                   7655: /*   hstepm=hstepm/stepm;  */
                   7656: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7657: /*                                fractional in yp1 *\/ */
                   7658: /*   anprojmean=yp; */
                   7659: /*   yp2=modf((yp1*12),&yp); */
                   7660: /*   mprojmean=yp; */
                   7661: /*   yp1=modf((yp2*30.5),&yp); */
                   7662: /*   jprojmean=yp; */
                   7663: /*   if(jprojmean==0) jprojmean=1; */
                   7664: /*   if(mprojmean==0) jprojmean=1; */
                   7665:        
1.225     brouard  7666: /*   i1=cptcoveff; */
1.218     brouard  7667: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7668:   
1.218     brouard  7669: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7670:   
1.218     brouard  7671: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7672:        
                   7673: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7674: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7675: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7676: /*       k=k+1; */
                   7677: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7678: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7679: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7680: /*       } */
                   7681: /*       fprintf(ficresfb," yearbproj age"); */
                   7682: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7683: /*                             for(i=1; i<=nlstate;i++)               */
                   7684: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7685: /*                             fprintf(ficresfb," p.%d",j); */
                   7686: /*       } */
                   7687: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7688: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7689: /*                             fprintf(ficresfb,"\n"); */
                   7690: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7691: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7692: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7693: /*                                     nhstepm = nhstepm/hstepm;  */
                   7694: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7695: /*                                     oldm=oldms;savm=savms; */
                   7696: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7697: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7698: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7699: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7700: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7701: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7702: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7703: /*                                             }  */
                   7704: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7705: /*                                                     ppij=0.; */
                   7706: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7707: /*                                                             if (mobilav==1)  */
                   7708: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7709: /*                                                             else { */
                   7710: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7711: /*                                                             } */
                   7712: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7713: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7714: /*                                                             } */
                   7715: /*                                                     } /\* end i *\/ */
                   7716: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7717: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7718: /*                                                     } */
                   7719: /*                                             }/\* end j *\/ */
                   7720: /*                                     } /\* end h *\/ */
                   7721: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7722: /*                             } /\* end agec *\/ */
                   7723: /*       } /\* end yearp *\/ */
                   7724: /*     } /\* end cptcod *\/ */
                   7725: /*   } /\* end  cptcov *\/ */
                   7726:        
                   7727: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7728:        
                   7729: /*   fclose(ficresfb); */
                   7730: /*   printf("End of Computing Back forecasting \n"); */
                   7731: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7732:        
1.218     brouard  7733: /* } */
1.217     brouard  7734: 
1.126     brouard  7735: /************** Forecasting *****not tested NB*************/
1.227     brouard  7736: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7737:   
1.227     brouard  7738: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7739: /*   int *popage; */
                   7740: /*   double calagedatem, agelim, kk1, kk2; */
                   7741: /*   double *popeffectif,*popcount; */
                   7742: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7743: /*   /\* double ***mobaverage; *\/ */
                   7744: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7745: 
1.227     brouard  7746: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7747: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7748: /*   agelim=AGESUP; */
                   7749: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7750:   
1.227     brouard  7751: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7752:   
                   7753:   
1.227     brouard  7754: /*   strcpy(filerespop,"POP_");  */
                   7755: /*   strcat(filerespop,fileresu); */
                   7756: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7757: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7758: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7759: /*   } */
                   7760: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7761: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7762: 
1.227     brouard  7763: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7764: 
1.227     brouard  7765: /*   /\* if (mobilav!=0) { *\/ */
                   7766: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7767: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7768: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7769: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7770: /*   /\*   } *\/ */
                   7771: /*   /\* } *\/ */
1.126     brouard  7772: 
1.227     brouard  7773: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7774: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7775:   
1.227     brouard  7776: /*   agelim=AGESUP; */
1.126     brouard  7777:   
1.227     brouard  7778: /*   hstepm=1; */
                   7779: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7780:        
1.227     brouard  7781: /*   if (popforecast==1) { */
                   7782: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7783: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7784: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7785: /*     }  */
                   7786: /*     popage=ivector(0,AGESUP); */
                   7787: /*     popeffectif=vector(0,AGESUP); */
                   7788: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7789:     
1.227     brouard  7790: /*     i=1;    */
                   7791: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7792:     
1.227     brouard  7793: /*     imx=i; */
                   7794: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7795: /*   } */
1.218     brouard  7796:   
1.227     brouard  7797: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7798: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7799: /*       k=k+1; */
                   7800: /*       fprintf(ficrespop,"\n#******"); */
                   7801: /*       for(j=1;j<=cptcoveff;j++) { */
                   7802: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7803: /*       } */
                   7804: /*       fprintf(ficrespop,"******\n"); */
                   7805: /*       fprintf(ficrespop,"# Age"); */
                   7806: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7807: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7808:       
1.227     brouard  7809: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7810: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7811:        
1.227     brouard  7812: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7813: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7814: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7815:          
1.227     brouard  7816: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7817: /*       oldm=oldms;savm=savms; */
                   7818: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7819:          
1.227     brouard  7820: /*       for (h=0; h<=nhstepm; h++){ */
                   7821: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7822: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7823: /*         }  */
                   7824: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7825: /*           kk1=0.;kk2=0; */
                   7826: /*           for(i=1; i<=nlstate;i++) {               */
                   7827: /*             if (mobilav==1)  */
                   7828: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7829: /*             else { */
                   7830: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7831: /*             } */
                   7832: /*           } */
                   7833: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7834: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7835: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7836: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7837: /*           } */
                   7838: /*         } */
                   7839: /*         for(i=1; i<=nlstate;i++){ */
                   7840: /*           kk1=0.; */
                   7841: /*           for(j=1; j<=nlstate;j++){ */
                   7842: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7843: /*           } */
                   7844: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7845: /*         } */
1.218     brouard  7846:            
1.227     brouard  7847: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7848: /*           for(j=1; j<=nlstate;j++)  */
                   7849: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7850: /*       } */
                   7851: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7852: /*     } */
                   7853: /*       } */
1.218     brouard  7854:       
1.227     brouard  7855: /*       /\******\/ */
1.218     brouard  7856:       
1.227     brouard  7857: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7858: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7859: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7860: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7861: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7862:          
1.227     brouard  7863: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7864: /*       oldm=oldms;savm=savms; */
                   7865: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7866: /*       for (h=0; h<=nhstepm; h++){ */
                   7867: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7868: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7869: /*         }  */
                   7870: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7871: /*           kk1=0.;kk2=0; */
                   7872: /*           for(i=1; i<=nlstate;i++) {               */
                   7873: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7874: /*           } */
                   7875: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7876: /*         } */
                   7877: /*       } */
                   7878: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7879: /*     } */
                   7880: /*       } */
                   7881: /*     }  */
                   7882: /*   } */
1.218     brouard  7883:   
1.227     brouard  7884: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7885:   
1.227     brouard  7886: /*   if (popforecast==1) { */
                   7887: /*     free_ivector(popage,0,AGESUP); */
                   7888: /*     free_vector(popeffectif,0,AGESUP); */
                   7889: /*     free_vector(popcount,0,AGESUP); */
                   7890: /*   } */
                   7891: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7892: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7893: /*   fclose(ficrespop); */
                   7894: /* } /\* End of popforecast *\/ */
1.218     brouard  7895:  
1.126     brouard  7896: int fileappend(FILE *fichier, char *optionfich)
                   7897: {
                   7898:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7899:     printf("Problem with file: %s\n", optionfich);
                   7900:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7901:     return (0);
                   7902:   }
                   7903:   fflush(fichier);
                   7904:   return (1);
                   7905: }
                   7906: 
                   7907: 
                   7908: /**************** function prwizard **********************/
                   7909: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7910: {
                   7911: 
                   7912:   /* Wizard to print covariance matrix template */
                   7913: 
1.164     brouard  7914:   char ca[32], cb[32];
                   7915:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7916:   int numlinepar;
                   7917: 
                   7918:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7919:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7920:   for(i=1; i <=nlstate; i++){
                   7921:     jj=0;
                   7922:     for(j=1; j <=nlstate+ndeath; j++){
                   7923:       if(j==i) continue;
                   7924:       jj++;
                   7925:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7926:       printf("%1d%1d",i,j);
                   7927:       fprintf(ficparo,"%1d%1d",i,j);
                   7928:       for(k=1; k<=ncovmodel;k++){
                   7929:        /*        printf(" %lf",param[i][j][k]); */
                   7930:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7931:        printf(" 0.");
                   7932:        fprintf(ficparo," 0.");
                   7933:       }
                   7934:       printf("\n");
                   7935:       fprintf(ficparo,"\n");
                   7936:     }
                   7937:   }
                   7938:   printf("# Scales (for hessian or gradient estimation)\n");
                   7939:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7940:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7941:   for(i=1; i <=nlstate; i++){
                   7942:     jj=0;
                   7943:     for(j=1; j <=nlstate+ndeath; j++){
                   7944:       if(j==i) continue;
                   7945:       jj++;
                   7946:       fprintf(ficparo,"%1d%1d",i,j);
                   7947:       printf("%1d%1d",i,j);
                   7948:       fflush(stdout);
                   7949:       for(k=1; k<=ncovmodel;k++){
                   7950:        /*      printf(" %le",delti3[i][j][k]); */
                   7951:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7952:        printf(" 0.");
                   7953:        fprintf(ficparo," 0.");
                   7954:       }
                   7955:       numlinepar++;
                   7956:       printf("\n");
                   7957:       fprintf(ficparo,"\n");
                   7958:     }
                   7959:   }
                   7960:   printf("# Covariance matrix\n");
                   7961: /* # 121 Var(a12)\n\ */
                   7962: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7963: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7964: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7965: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7966: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7967: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7968: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7969:   fflush(stdout);
                   7970:   fprintf(ficparo,"# Covariance matrix\n");
                   7971:   /* # 121 Var(a12)\n\ */
                   7972:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7973:   /* #   ...\n\ */
                   7974:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7975:   
                   7976:   for(itimes=1;itimes<=2;itimes++){
                   7977:     jj=0;
                   7978:     for(i=1; i <=nlstate; i++){
                   7979:       for(j=1; j <=nlstate+ndeath; j++){
                   7980:        if(j==i) continue;
                   7981:        for(k=1; k<=ncovmodel;k++){
                   7982:          jj++;
                   7983:          ca[0]= k+'a'-1;ca[1]='\0';
                   7984:          if(itimes==1){
                   7985:            printf("#%1d%1d%d",i,j,k);
                   7986:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7987:          }else{
                   7988:            printf("%1d%1d%d",i,j,k);
                   7989:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7990:            /*  printf(" %.5le",matcov[i][j]); */
                   7991:          }
                   7992:          ll=0;
                   7993:          for(li=1;li <=nlstate; li++){
                   7994:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7995:              if(lj==li) continue;
                   7996:              for(lk=1;lk<=ncovmodel;lk++){
                   7997:                ll++;
                   7998:                if(ll<=jj){
                   7999:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8000:                  if(ll<jj){
                   8001:                    if(itimes==1){
                   8002:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8003:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8004:                    }else{
                   8005:                      printf(" 0.");
                   8006:                      fprintf(ficparo," 0.");
                   8007:                    }
                   8008:                  }else{
                   8009:                    if(itimes==1){
                   8010:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8011:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8012:                    }else{
                   8013:                      printf(" 0.");
                   8014:                      fprintf(ficparo," 0.");
                   8015:                    }
                   8016:                  }
                   8017:                }
                   8018:              } /* end lk */
                   8019:            } /* end lj */
                   8020:          } /* end li */
                   8021:          printf("\n");
                   8022:          fprintf(ficparo,"\n");
                   8023:          numlinepar++;
                   8024:        } /* end k*/
                   8025:       } /*end j */
                   8026:     } /* end i */
                   8027:   } /* end itimes */
                   8028: 
                   8029: } /* end of prwizard */
                   8030: /******************* Gompertz Likelihood ******************************/
                   8031: double gompertz(double x[])
                   8032: { 
                   8033:   double A,B,L=0.0,sump=0.,num=0.;
                   8034:   int i,n=0; /* n is the size of the sample */
                   8035: 
1.220     brouard  8036:   for (i=1;i<=imx ; i++) {
1.126     brouard  8037:     sump=sump+weight[i];
                   8038:     /*    sump=sump+1;*/
                   8039:     num=num+1;
                   8040:   }
                   8041:  
                   8042:  
                   8043:   /* for (i=0; i<=imx; i++) 
                   8044:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8045: 
                   8046:   for (i=1;i<=imx ; i++)
                   8047:     {
                   8048:       if (cens[i] == 1 && wav[i]>1)
                   8049:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8050:       
                   8051:       if (cens[i] == 0 && wav[i]>1)
                   8052:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8053:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8054:       
                   8055:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8056:       if (wav[i] > 1 ) { /* ??? */
                   8057:        L=L+A*weight[i];
                   8058:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8059:       }
                   8060:     }
                   8061: 
                   8062:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8063:  
                   8064:   return -2*L*num/sump;
                   8065: }
                   8066: 
1.136     brouard  8067: #ifdef GSL
                   8068: /******************* Gompertz_f Likelihood ******************************/
                   8069: double gompertz_f(const gsl_vector *v, void *params)
                   8070: { 
                   8071:   double A,B,LL=0.0,sump=0.,num=0.;
                   8072:   double *x= (double *) v->data;
                   8073:   int i,n=0; /* n is the size of the sample */
                   8074: 
                   8075:   for (i=0;i<=imx-1 ; i++) {
                   8076:     sump=sump+weight[i];
                   8077:     /*    sump=sump+1;*/
                   8078:     num=num+1;
                   8079:   }
                   8080:  
                   8081:  
                   8082:   /* for (i=0; i<=imx; i++) 
                   8083:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8084:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8085:   for (i=1;i<=imx ; i++)
                   8086:     {
                   8087:       if (cens[i] == 1 && wav[i]>1)
                   8088:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8089:       
                   8090:       if (cens[i] == 0 && wav[i]>1)
                   8091:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8092:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8093:       
                   8094:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8095:       if (wav[i] > 1 ) { /* ??? */
                   8096:        LL=LL+A*weight[i];
                   8097:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8098:       }
                   8099:     }
                   8100: 
                   8101:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8102:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8103:  
                   8104:   return -2*LL*num/sump;
                   8105: }
                   8106: #endif
                   8107: 
1.126     brouard  8108: /******************* Printing html file ***********/
1.201     brouard  8109: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8110:                  int lastpass, int stepm, int weightopt, char model[],\
                   8111:                  int imx,  double p[],double **matcov,double agemortsup){
                   8112:   int i,k;
                   8113: 
                   8114:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8115:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8116:   for (i=1;i<=2;i++) 
                   8117:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8118:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8119:   fprintf(fichtm,"</ul>");
                   8120: 
                   8121: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8122: 
                   8123:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8124: 
                   8125:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8126:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8127: 
                   8128:  
                   8129:   fflush(fichtm);
                   8130: }
                   8131: 
                   8132: /******************* Gnuplot file **************/
1.201     brouard  8133: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8134: 
                   8135:   char dirfileres[132],optfileres[132];
1.164     brouard  8136: 
1.126     brouard  8137:   int ng;
                   8138: 
                   8139: 
                   8140:   /*#ifdef windows */
                   8141:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8142:     /*#endif */
                   8143: 
                   8144: 
                   8145:   strcpy(dirfileres,optionfilefiname);
                   8146:   strcpy(optfileres,"vpl");
1.199     brouard  8147:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8148:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8149:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8150:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8151:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8152: 
                   8153: } 
                   8154: 
1.136     brouard  8155: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8156: {
1.126     brouard  8157: 
1.136     brouard  8158:   /*-------- data file ----------*/
                   8159:   FILE *fic;
                   8160:   char dummy[]="                         ";
1.240     brouard  8161:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8162:   int lstra;
1.136     brouard  8163:   int linei, month, year,iout;
                   8164:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8165:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8166:   char *stratrunc;
1.223     brouard  8167: 
1.240     brouard  8168:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8169:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8170: 
1.240     brouard  8171:   for(v=1; v <=ncovcol;v++){
                   8172:     DummyV[v]=0;
                   8173:     FixedV[v]=0;
                   8174:   }
                   8175:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8176:     DummyV[v]=1;
                   8177:     FixedV[v]=0;
                   8178:   }
                   8179:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8180:     DummyV[v]=0;
                   8181:     FixedV[v]=1;
                   8182:   }
                   8183:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8184:     DummyV[v]=1;
                   8185:     FixedV[v]=1;
                   8186:   }
                   8187:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8188:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8189:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8190:   }
1.126     brouard  8191: 
1.136     brouard  8192:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8193:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8194:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8195:   }
1.126     brouard  8196: 
1.136     brouard  8197:   i=1;
                   8198:   linei=0;
                   8199:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8200:     linei=linei+1;
                   8201:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8202:       if(line[j] == '\t')
                   8203:        line[j] = ' ';
                   8204:     }
                   8205:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8206:       ;
                   8207:     };
                   8208:     line[j+1]=0;  /* Trims blanks at end of line */
                   8209:     if(line[0]=='#'){
                   8210:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8211:       printf("Comment line\n%s\n",line);
                   8212:       continue;
                   8213:     }
                   8214:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8215:     strcpy(line, linetmp);
1.223     brouard  8216:     
                   8217:     /* Loops on waves */
                   8218:     for (j=maxwav;j>=1;j--){
                   8219:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8220:        cutv(stra, strb, line, ' '); 
                   8221:        if(strb[0]=='.') { /* Missing value */
                   8222:          lval=-1;
                   8223:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8224:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8225:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8226:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8227:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8228:            return 1;
                   8229:          }
                   8230:        }else{
                   8231:          errno=0;
                   8232:          /* what_kind_of_number(strb); */
                   8233:          dval=strtod(strb,&endptr); 
                   8234:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8235:          /* if(strb != endptr && *endptr == '\0') */
                   8236:          /*    dval=dlval; */
                   8237:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8238:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8239:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8240:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8241:            return 1;
                   8242:          }
                   8243:          cotqvar[j][iv][i]=dval; 
                   8244:          cotvar[j][ntv+iv][i]=dval; 
                   8245:        }
                   8246:        strcpy(line,stra);
1.223     brouard  8247:       }/* end loop ntqv */
1.225     brouard  8248:       
1.223     brouard  8249:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8250:        cutv(stra, strb, line, ' '); 
                   8251:        if(strb[0]=='.') { /* Missing value */
                   8252:          lval=-1;
                   8253:        }else{
                   8254:          errno=0;
                   8255:          lval=strtol(strb,&endptr,10); 
                   8256:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8257:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8258:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8259:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8260:            return 1;
                   8261:          }
                   8262:        }
                   8263:        if(lval <-1 || lval >1){
                   8264:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8265:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8266:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8267:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8268:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8269:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8270:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8271:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8272:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8273:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8274:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8275:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8276:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8277:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8278:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8279:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8280:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8281:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8282:          return 1;
                   8283:        }
                   8284:        cotvar[j][iv][i]=(double)(lval);
                   8285:        strcpy(line,stra);
1.223     brouard  8286:       }/* end loop ntv */
1.225     brouard  8287:       
1.223     brouard  8288:       /* Statuses  at wave */
1.137     brouard  8289:       cutv(stra, strb, line, ' '); 
1.223     brouard  8290:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8291:        lval=-1;
1.136     brouard  8292:       }else{
1.238     brouard  8293:        errno=0;
                   8294:        lval=strtol(strb,&endptr,10); 
                   8295:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8296:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8297:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8298:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8299:          return 1;
                   8300:        }
1.136     brouard  8301:       }
1.225     brouard  8302:       
1.136     brouard  8303:       s[j][i]=lval;
1.225     brouard  8304:       
1.223     brouard  8305:       /* Date of Interview */
1.136     brouard  8306:       strcpy(line,stra);
                   8307:       cutv(stra, strb,line,' ');
1.169     brouard  8308:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8309:       }
1.169     brouard  8310:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8311:        month=99;
                   8312:        year=9999;
1.136     brouard  8313:       }else{
1.225     brouard  8314:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8315:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8316:        return 1;
1.136     brouard  8317:       }
                   8318:       anint[j][i]= (double) year; 
                   8319:       mint[j][i]= (double)month; 
                   8320:       strcpy(line,stra);
1.223     brouard  8321:     } /* End loop on waves */
1.225     brouard  8322:     
1.223     brouard  8323:     /* Date of death */
1.136     brouard  8324:     cutv(stra, strb,line,' '); 
1.169     brouard  8325:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8326:     }
1.169     brouard  8327:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8328:       month=99;
                   8329:       year=9999;
                   8330:     }else{
1.141     brouard  8331:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8332:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8333:       return 1;
1.136     brouard  8334:     }
                   8335:     andc[i]=(double) year; 
                   8336:     moisdc[i]=(double) month; 
                   8337:     strcpy(line,stra);
                   8338:     
1.223     brouard  8339:     /* Date of birth */
1.136     brouard  8340:     cutv(stra, strb,line,' '); 
1.169     brouard  8341:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8342:     }
1.169     brouard  8343:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8344:       month=99;
                   8345:       year=9999;
                   8346:     }else{
1.141     brouard  8347:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8348:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8349:       return 1;
1.136     brouard  8350:     }
                   8351:     if (year==9999) {
1.141     brouard  8352:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8353:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8354:       return 1;
                   8355:       
1.136     brouard  8356:     }
                   8357:     annais[i]=(double)(year);
                   8358:     moisnais[i]=(double)(month); 
                   8359:     strcpy(line,stra);
1.225     brouard  8360:     
1.223     brouard  8361:     /* Sample weight */
1.136     brouard  8362:     cutv(stra, strb,line,' '); 
                   8363:     errno=0;
                   8364:     dval=strtod(strb,&endptr); 
                   8365:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8366:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8367:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8368:       fflush(ficlog);
                   8369:       return 1;
                   8370:     }
                   8371:     weight[i]=dval; 
                   8372:     strcpy(line,stra);
1.225     brouard  8373:     
1.223     brouard  8374:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8375:       cutv(stra, strb, line, ' '); 
                   8376:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8377:        lval=-1;
1.223     brouard  8378:       }else{
1.225     brouard  8379:        errno=0;
                   8380:        /* what_kind_of_number(strb); */
                   8381:        dval=strtod(strb,&endptr);
                   8382:        /* if(strb != endptr && *endptr == '\0') */
                   8383:        /*   dval=dlval; */
                   8384:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8385:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8386:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8387:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8388:          return 1;
                   8389:        }
                   8390:        coqvar[iv][i]=dval; 
1.226     brouard  8391:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8392:       }
                   8393:       strcpy(line,stra);
                   8394:     }/* end loop nqv */
1.136     brouard  8395:     
1.223     brouard  8396:     /* Covariate values */
1.136     brouard  8397:     for (j=ncovcol;j>=1;j--){
                   8398:       cutv(stra, strb,line,' '); 
1.223     brouard  8399:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8400:        lval=-1;
1.136     brouard  8401:       }else{
1.225     brouard  8402:        errno=0;
                   8403:        lval=strtol(strb,&endptr,10); 
                   8404:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8405:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8406:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8407:          return 1;
                   8408:        }
1.136     brouard  8409:       }
                   8410:       if(lval <-1 || lval >1){
1.225     brouard  8411:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8412:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8413:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8414:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8415:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8416:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8417:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8418:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8419:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8420:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8421:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8422:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8423:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8424:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8425:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8426:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8427:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8428:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8429:        return 1;
1.136     brouard  8430:       }
                   8431:       covar[j][i]=(double)(lval);
                   8432:       strcpy(line,stra);
                   8433:     }  
                   8434:     lstra=strlen(stra);
1.225     brouard  8435:     
1.136     brouard  8436:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8437:       stratrunc = &(stra[lstra-9]);
                   8438:       num[i]=atol(stratrunc);
                   8439:     }
                   8440:     else
                   8441:       num[i]=atol(stra);
                   8442:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8443:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8444:     
                   8445:     i=i+1;
                   8446:   } /* End loop reading  data */
1.225     brouard  8447:   
1.136     brouard  8448:   *imax=i-1; /* Number of individuals */
                   8449:   fclose(fic);
1.225     brouard  8450:   
1.136     brouard  8451:   return (0);
1.164     brouard  8452:   /* endread: */
1.225     brouard  8453:   printf("Exiting readdata: ");
                   8454:   fclose(fic);
                   8455:   return (1);
1.223     brouard  8456: }
1.126     brouard  8457: 
1.234     brouard  8458: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8459:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8460:   while (*p2 == ' ')
1.234     brouard  8461:     p2++; 
                   8462:   /* while ((*p1++ = *p2++) !=0) */
                   8463:   /*   ; */
                   8464:   /* do */
                   8465:   /*   while (*p2 == ' ') */
                   8466:   /*     p2++; */
                   8467:   /* while (*p1++ == *p2++); */
                   8468:   *stri=p2; 
1.145     brouard  8469: }
                   8470: 
1.235     brouard  8471: int decoderesult ( char resultline[], int nres)
1.230     brouard  8472: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8473: {
1.235     brouard  8474:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8475:   char resultsav[MAXLINE];
1.234     brouard  8476:   int resultmodel[MAXLINE];
                   8477:   int modelresult[MAXLINE];
1.230     brouard  8478:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8479: 
1.234     brouard  8480:   removefirstspace(&resultline);
1.233     brouard  8481:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8482: 
                   8483:   if (strstr(resultline,"v") !=0){
                   8484:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8485:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8486:     return 1;
                   8487:   }
                   8488:   trimbb(resultsav, resultline);
                   8489:   if (strlen(resultsav) >1){
                   8490:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8491:   }
1.253     brouard  8492:   if(j == 0){ /* Resultline but no = */
                   8493:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8494:     return (0);
                   8495:   }
                   8496:     
1.234     brouard  8497:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8498:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8499:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8500:   }
                   8501:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8502:     if(nbocc(resultsav,'=') >1){
                   8503:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8504:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8505:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8506:     }else
                   8507:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8508:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8509:     
1.230     brouard  8510:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8511:     Tvarsel[k]=atoi(strc);
                   8512:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8513:     /* cptcovsel++;     */
                   8514:     if (nbocc(stra,'=') >0)
                   8515:       strcpy(resultsav,stra); /* and analyzes it */
                   8516:   }
1.235     brouard  8517:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8518:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8519:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8520:       match=0;
1.236     brouard  8521:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8522:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8523:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8524:          match=1;
                   8525:          break;
                   8526:        }
                   8527:       }
                   8528:       if(match == 0){
                   8529:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8530:       }
                   8531:     }
                   8532:   }
1.235     brouard  8533:   /* Checking for missing or useless values in comparison of current model needs */
                   8534:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8535:     match=0;
1.235     brouard  8536:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8537:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8538:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8539:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8540:          ++match;
                   8541:        }
                   8542:       }
                   8543:     }
                   8544:     if(match == 0){
                   8545:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8546:     }else if(match > 1){
                   8547:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8548:     }
                   8549:   }
1.235     brouard  8550:       
1.234     brouard  8551:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8552:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8553:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8554:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8555:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8556:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8557:   /*    1 0 0 0 */
                   8558:   /*    2 1 0 0 */
                   8559:   /*    3 0 1 0 */ 
                   8560:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8561:   /*    5 0 0 1 */
                   8562:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8563:   /*    7 0 1 1 */
                   8564:   /*    8 1 1 1 */
1.237     brouard  8565:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8566:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8567:   /* V5*age V5 known which value for nres?  */
                   8568:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8569:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8570:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8571:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8572:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8573:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8574:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8575:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8576:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8577:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8578:       k4++;;
                   8579:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8580:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8581:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8582:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8583:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8584:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8585:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8586:       k4q++;;
                   8587:     }
                   8588:   }
1.234     brouard  8589:   
1.235     brouard  8590:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8591:   return (0);
                   8592: }
1.235     brouard  8593: 
1.230     brouard  8594: int decodemodel( char model[], int lastobs)
                   8595:  /**< This routine decodes the model and returns:
1.224     brouard  8596:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8597:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8598:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8599:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8600:        * - cptcovage number of covariates with age*products =2
                   8601:        * - cptcovs number of simple covariates
                   8602:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8603:        *     which is a new column after the 9 (ncovcol) variables. 
                   8604:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8605:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8606:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8607:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8608:        */
1.136     brouard  8609: {
1.238     brouard  8610:   int i, j, k, ks, v;
1.227     brouard  8611:   int  j1, k1, k2, k3, k4;
1.136     brouard  8612:   char modelsav[80];
1.145     brouard  8613:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8614:   char *strpt;
1.136     brouard  8615: 
1.145     brouard  8616:   /*removespace(model);*/
1.136     brouard  8617:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8618:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8619:     if (strstr(model,"AGE") !=0){
1.192     brouard  8620:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8621:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8622:       return 1;
                   8623:     }
1.141     brouard  8624:     if (strstr(model,"v") !=0){
                   8625:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8626:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8627:       return 1;
                   8628:     }
1.187     brouard  8629:     strcpy(modelsav,model); 
                   8630:     if ((strpt=strstr(model,"age*age")) !=0){
                   8631:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8632:       if(strpt != model){
1.234     brouard  8633:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8634:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8635:  corresponding column of parameters.\n",model);
1.234     brouard  8636:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8637:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8638:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8639:        return 1;
1.225     brouard  8640:       }
1.187     brouard  8641:       nagesqr=1;
                   8642:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8643:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8644:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8645:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8646:       else 
1.234     brouard  8647:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8648:     }else
                   8649:       nagesqr=0;
                   8650:     if (strlen(modelsav) >1){
                   8651:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8652:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8653:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8654:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8655:                     * cst, age and age*age 
                   8656:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8657:       /* including age products which are counted in cptcovage.
                   8658:        * but the covariates which are products must be treated 
                   8659:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8660:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8661:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8662:       
                   8663:       
1.187     brouard  8664:       /*   Design
                   8665:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8666:        *  <          ncovcol=8                >
                   8667:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8668:        *   k=  1    2      3       4     5       6      7        8
                   8669:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8670:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8671:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8672:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8673:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8674:        *  Tage[++cptcovage]=k
                   8675:        *       if products, new covar are created after ncovcol with k1
                   8676:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8677:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8678:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8679:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8680:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8681:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8682:        *  <          ncovcol=8                >
                   8683:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8684:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8685:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8686:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8687:        * p Tprod[1]@2={                         6, 5}
                   8688:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8689:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8690:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8691:        *How to reorganize?
                   8692:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8693:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8694:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8695:        * Struct []
                   8696:        */
1.225     brouard  8697:       
1.187     brouard  8698:       /* This loop fills the array Tvar from the string 'model'.*/
                   8699:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8700:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8701:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8702:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8703:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8704:       /*       k=1 Tvar[1]=2 (from V2) */
                   8705:       /*       k=5 Tvar[5] */
                   8706:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8707:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8708:       /*       } */
1.198     brouard  8709:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8710:       /*
                   8711:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8712:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8713:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8714:       }
1.187     brouard  8715:       cptcovage=0;
                   8716:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8717:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8718:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8719:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8720:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8721:        /*scanf("%d",i);*/
                   8722:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8723:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8724:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8725:            /* covar is not filled and then is empty */
                   8726:            cptcovprod--;
                   8727:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8728:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8729:            Typevar[k]=1;  /* 1 for age product */
                   8730:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8731:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8732:            /*printf("stre=%s ", stre);*/
                   8733:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8734:            cptcovprod--;
                   8735:            cutl(stre,strb,strc,'V');
                   8736:            Tvar[k]=atoi(stre);
                   8737:            Typevar[k]=1;  /* 1 for age product */
                   8738:            cptcovage++;
                   8739:            Tage[cptcovage]=k;
                   8740:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8741:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8742:            cptcovn++;
                   8743:            cptcovprodnoage++;k1++;
                   8744:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8745:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8746:                                                because this model-covariate is a construction we invent a new column
                   8747:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8748:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8749:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8750:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8751:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8752:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8753:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8754:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8755:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8756:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8757:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8758:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8759:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8760:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8761:            for (i=1; i<=lastobs;i++){
                   8762:              /* Computes the new covariate which is a product of
                   8763:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8764:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8765:            }
                   8766:          } /* End age is not in the model */
                   8767:        } /* End if model includes a product */
                   8768:        else { /* no more sum */
                   8769:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8770:          /*  scanf("%d",i);*/
                   8771:          cutl(strd,strc,strb,'V');
                   8772:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8773:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8774:          Tvar[k]=atoi(strd);
                   8775:          Typevar[k]=0;  /* 0 for simple covariates */
                   8776:        }
                   8777:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8778:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8779:                                  scanf("%d",i);*/
1.187     brouard  8780:       } /* end of loop + on total covariates */
                   8781:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8782:   } /* end if strlen(model == 0) */
1.136     brouard  8783:   
                   8784:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8785:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8786:   
1.136     brouard  8787:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8788:      printf("cptcovprod=%d ", cptcovprod);
                   8789:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8790:      scanf("%d ",i);*/
                   8791: 
                   8792: 
1.230     brouard  8793: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8794:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8795: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8796:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8797:    k =           1    2   3     4       5       6      7      8        9
                   8798:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8799:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8800:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8801:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8802:          Tmodelind[combination of covar]=k;
1.225     brouard  8803: */  
                   8804: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8805:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8806:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8807:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8808:   printf("Model=%s\n\
                   8809: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8810: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8811: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8812:   fprintf(ficlog,"Model=%s\n\
                   8813: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8814: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8815: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8816:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8817:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8818:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8819:       Fixed[k]= 0;
                   8820:       Dummy[k]= 0;
1.225     brouard  8821:       ncoveff++;
1.232     brouard  8822:       ncovf++;
1.234     brouard  8823:       nsd++;
                   8824:       modell[k].maintype= FTYPE;
                   8825:       TvarsD[nsd]=Tvar[k];
                   8826:       TvarsDind[nsd]=k;
                   8827:       TvarF[ncovf]=Tvar[k];
                   8828:       TvarFind[ncovf]=k;
                   8829:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8830:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8831:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8832:       Fixed[k]= 0;
                   8833:       Dummy[k]= 0;
                   8834:       ncoveff++;
                   8835:       ncovf++;
                   8836:       modell[k].maintype= FTYPE;
                   8837:       TvarF[ncovf]=Tvar[k];
                   8838:       TvarFind[ncovf]=k;
1.230     brouard  8839:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8840:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8841:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8842:       Fixed[k]= 0;
                   8843:       Dummy[k]= 1;
1.230     brouard  8844:       nqfveff++;
1.234     brouard  8845:       modell[k].maintype= FTYPE;
                   8846:       modell[k].subtype= FQ;
                   8847:       nsq++;
                   8848:       TvarsQ[nsq]=Tvar[k];
                   8849:       TvarsQind[nsq]=k;
1.232     brouard  8850:       ncovf++;
1.234     brouard  8851:       TvarF[ncovf]=Tvar[k];
                   8852:       TvarFind[ncovf]=k;
1.231     brouard  8853:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8854:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8855:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8856:       Fixed[k]= 1;
                   8857:       Dummy[k]= 0;
1.225     brouard  8858:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8859:       modell[k].maintype= VTYPE;
                   8860:       modell[k].subtype= VD;
                   8861:       nsd++;
                   8862:       TvarsD[nsd]=Tvar[k];
                   8863:       TvarsDind[nsd]=k;
                   8864:       ncovv++; /* Only simple time varying variables */
                   8865:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8866:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8867:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8868:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8869:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8870:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8871:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8872:       Fixed[k]= 1;
                   8873:       Dummy[k]= 1;
                   8874:       nqtveff++;
                   8875:       modell[k].maintype= VTYPE;
                   8876:       modell[k].subtype= VQ;
                   8877:       ncovv++; /* Only simple time varying variables */
                   8878:       nsq++;
                   8879:       TvarsQ[nsq]=Tvar[k];
                   8880:       TvarsQind[nsq]=k;
                   8881:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8882:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8883:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8884:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8885:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8886:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8887:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8888:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8889:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8890:       ncova++;
                   8891:       TvarA[ncova]=Tvar[k];
                   8892:       TvarAind[ncova]=k;
1.231     brouard  8893:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8894:        Fixed[k]= 2;
                   8895:        Dummy[k]= 2;
                   8896:        modell[k].maintype= ATYPE;
                   8897:        modell[k].subtype= APFD;
                   8898:        /* ncoveff++; */
1.227     brouard  8899:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8900:        Fixed[k]= 2;
                   8901:        Dummy[k]= 3;
                   8902:        modell[k].maintype= ATYPE;
                   8903:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8904:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8905:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8906:        Fixed[k]= 3;
                   8907:        Dummy[k]= 2;
                   8908:        modell[k].maintype= ATYPE;
                   8909:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8910:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8911:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8912:        Fixed[k]= 3;
                   8913:        Dummy[k]= 3;
                   8914:        modell[k].maintype= ATYPE;
                   8915:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8916:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8917:       }
                   8918:     }else if (Typevar[k] == 2) {  /* product without age */
                   8919:       k1=Tposprod[k];
                   8920:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8921:        if(Tvard[k1][2] <=ncovcol){
                   8922:          Fixed[k]= 1;
                   8923:          Dummy[k]= 0;
                   8924:          modell[k].maintype= FTYPE;
                   8925:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8926:          ncovf++; /* Fixed variables without age */
                   8927:          TvarF[ncovf]=Tvar[k];
                   8928:          TvarFind[ncovf]=k;
                   8929:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8930:          Fixed[k]= 0;  /* or 2 ?*/
                   8931:          Dummy[k]= 1;
                   8932:          modell[k].maintype= FTYPE;
                   8933:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8934:          ncovf++; /* Varying variables without age */
                   8935:          TvarF[ncovf]=Tvar[k];
                   8936:          TvarFind[ncovf]=k;
                   8937:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8938:          Fixed[k]= 1;
                   8939:          Dummy[k]= 0;
                   8940:          modell[k].maintype= VTYPE;
                   8941:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8942:          ncovv++; /* Varying variables without age */
                   8943:          TvarV[ncovv]=Tvar[k];
                   8944:          TvarVind[ncovv]=k;
                   8945:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8946:          Fixed[k]= 1;
                   8947:          Dummy[k]= 1;
                   8948:          modell[k].maintype= VTYPE;
                   8949:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8950:          ncovv++; /* Varying variables without age */
                   8951:          TvarV[ncovv]=Tvar[k];
                   8952:          TvarVind[ncovv]=k;
                   8953:        }
1.227     brouard  8954:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8955:        if(Tvard[k1][2] <=ncovcol){
                   8956:          Fixed[k]= 0;  /* or 2 ?*/
                   8957:          Dummy[k]= 1;
                   8958:          modell[k].maintype= FTYPE;
                   8959:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8960:          ncovf++; /* Fixed variables without age */
                   8961:          TvarF[ncovf]=Tvar[k];
                   8962:          TvarFind[ncovf]=k;
                   8963:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8964:          Fixed[k]= 1;
                   8965:          Dummy[k]= 1;
                   8966:          modell[k].maintype= VTYPE;
                   8967:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8968:          ncovv++; /* Varying variables without age */
                   8969:          TvarV[ncovv]=Tvar[k];
                   8970:          TvarVind[ncovv]=k;
                   8971:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8972:          Fixed[k]= 1;
                   8973:          Dummy[k]= 1;
                   8974:          modell[k].maintype= VTYPE;
                   8975:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8976:          ncovv++; /* Varying variables without age */
                   8977:          TvarV[ncovv]=Tvar[k];
                   8978:          TvarVind[ncovv]=k;
                   8979:          ncovv++; /* Varying variables without age */
                   8980:          TvarV[ncovv]=Tvar[k];
                   8981:          TvarVind[ncovv]=k;
                   8982:        }
1.227     brouard  8983:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8984:        if(Tvard[k1][2] <=ncovcol){
                   8985:          Fixed[k]= 1;
                   8986:          Dummy[k]= 1;
                   8987:          modell[k].maintype= VTYPE;
                   8988:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8989:          ncovv++; /* Varying variables without age */
                   8990:          TvarV[ncovv]=Tvar[k];
                   8991:          TvarVind[ncovv]=k;
                   8992:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8993:          Fixed[k]= 1;
                   8994:          Dummy[k]= 1;
                   8995:          modell[k].maintype= VTYPE;
                   8996:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8997:          ncovv++; /* Varying variables without age */
                   8998:          TvarV[ncovv]=Tvar[k];
                   8999:          TvarVind[ncovv]=k;
                   9000:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9001:          Fixed[k]= 1;
                   9002:          Dummy[k]= 0;
                   9003:          modell[k].maintype= VTYPE;
                   9004:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9005:          ncovv++; /* Varying variables without age */
                   9006:          TvarV[ncovv]=Tvar[k];
                   9007:          TvarVind[ncovv]=k;
                   9008:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9009:          Fixed[k]= 1;
                   9010:          Dummy[k]= 1;
                   9011:          modell[k].maintype= VTYPE;
                   9012:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9013:          ncovv++; /* Varying variables without age */
                   9014:          TvarV[ncovv]=Tvar[k];
                   9015:          TvarVind[ncovv]=k;
                   9016:        }
1.227     brouard  9017:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9018:        if(Tvard[k1][2] <=ncovcol){
                   9019:          Fixed[k]= 1;
                   9020:          Dummy[k]= 1;
                   9021:          modell[k].maintype= VTYPE;
                   9022:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9023:          ncovv++; /* Varying variables without age */
                   9024:          TvarV[ncovv]=Tvar[k];
                   9025:          TvarVind[ncovv]=k;
                   9026:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9027:          Fixed[k]= 1;
                   9028:          Dummy[k]= 1;
                   9029:          modell[k].maintype= VTYPE;
                   9030:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9031:          ncovv++; /* Varying variables without age */
                   9032:          TvarV[ncovv]=Tvar[k];
                   9033:          TvarVind[ncovv]=k;
                   9034:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9035:          Fixed[k]= 1;
                   9036:          Dummy[k]= 1;
                   9037:          modell[k].maintype= VTYPE;
                   9038:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9039:          ncovv++; /* Varying variables without age */
                   9040:          TvarV[ncovv]=Tvar[k];
                   9041:          TvarVind[ncovv]=k;
                   9042:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9043:          Fixed[k]= 1;
                   9044:          Dummy[k]= 1;
                   9045:          modell[k].maintype= VTYPE;
                   9046:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9047:          ncovv++; /* Varying variables without age */
                   9048:          TvarV[ncovv]=Tvar[k];
                   9049:          TvarVind[ncovv]=k;
                   9050:        }
1.227     brouard  9051:       }else{
1.240     brouard  9052:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9053:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9054:       } /*end k1*/
1.225     brouard  9055:     }else{
1.226     brouard  9056:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9057:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9058:     }
1.227     brouard  9059:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9060:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9061:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9062:   }
                   9063:   /* Searching for doublons in the model */
                   9064:   for(k1=1; k1<= cptcovt;k1++){
                   9065:     for(k2=1; k2 <k1;k2++){
                   9066:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9067:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9068:          if(Tvar[k1]==Tvar[k2]){
                   9069:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9070:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9071:            return(1);
                   9072:          }
                   9073:        }else if (Typevar[k1] ==2){
                   9074:          k3=Tposprod[k1];
                   9075:          k4=Tposprod[k2];
                   9076:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9077:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9078:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9079:            return(1);
                   9080:          }
                   9081:        }
1.227     brouard  9082:       }
                   9083:     }
1.225     brouard  9084:   }
                   9085:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9086:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9087:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9088:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9089:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9090:   /*endread:*/
1.225     brouard  9091:   printf("Exiting decodemodel: ");
                   9092:   return (1);
1.136     brouard  9093: }
                   9094: 
1.169     brouard  9095: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9096: {/* Check ages at death */
1.136     brouard  9097:   int i, m;
1.218     brouard  9098:   int firstone=0;
                   9099:   
1.136     brouard  9100:   for (i=1; i<=imx; i++) {
                   9101:     for(m=2; (m<= maxwav); m++) {
                   9102:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9103:        anint[m][i]=9999;
1.216     brouard  9104:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9105:          s[m][i]=-1;
1.136     brouard  9106:       }
                   9107:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.259   ! brouard  9108:        *nbwarn = *nbwarn + 1;
1.218     brouard  9109:        if(firstone == 0){
                   9110:          firstone=1;
1.259   ! brouard  9111:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we believe in a death.\nOther similar cases in log file\n", *nbwarn,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9112:        }
1.259   ! brouard  9113:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we believe in a death.\nOther similar cases in log file\n", *nbwarn,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
        !          9114:        /* s[m][i]=-1; */ /* Keeping the death status */
1.136     brouard  9115:       }
                   9116:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9117:        (*nberr)++;
1.259   ! brouard  9118:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
        !          9119:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
        !          9120:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9121:       }
                   9122:     }
                   9123:   }
                   9124: 
                   9125:   for (i=1; i<=imx; i++)  {
                   9126:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9127:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9128:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9129:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9130:          if(agedc[i]>0){
                   9131:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9132:              agev[m][i]=agedc[i];
1.214     brouard  9133:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9134:            }else {
1.136     brouard  9135:              if ((int)andc[i]!=9999){
                   9136:                nbwarn++;
                   9137:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9138:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9139:                agev[m][i]=-1;
                   9140:              }
                   9141:            }
1.169     brouard  9142:          } /* agedc > 0 */
1.214     brouard  9143:        } /* end if */
1.136     brouard  9144:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9145:                                 years but with the precision of a month */
                   9146:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9147:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9148:            agev[m][i]=1;
                   9149:          else if(agev[m][i] < *agemin){ 
                   9150:            *agemin=agev[m][i];
                   9151:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9152:          }
                   9153:          else if(agev[m][i] >*agemax){
                   9154:            *agemax=agev[m][i];
1.156     brouard  9155:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9156:          }
                   9157:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9158:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9159:        } /* en if 9*/
1.136     brouard  9160:        else { /* =9 */
1.214     brouard  9161:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9162:          agev[m][i]=1;
                   9163:          s[m][i]=-1;
                   9164:        }
                   9165:       }
1.214     brouard  9166:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9167:        agev[m][i]=1;
1.214     brouard  9168:       else{
                   9169:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9170:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9171:        agev[m][i]=0;
                   9172:       }
                   9173:     } /* End for lastpass */
                   9174:   }
1.136     brouard  9175:     
                   9176:   for (i=1; i<=imx; i++)  {
                   9177:     for(m=firstpass; (m<=lastpass); m++){
                   9178:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9179:        (*nberr)++;
1.136     brouard  9180:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9181:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9182:        return 1;
                   9183:       }
                   9184:     }
                   9185:   }
                   9186: 
                   9187:   /*for (i=1; i<=imx; i++){
                   9188:   for (m=firstpass; (m<lastpass); m++){
                   9189:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9190: }
                   9191: 
                   9192: }*/
                   9193: 
                   9194: 
1.139     brouard  9195:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9196:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9197: 
                   9198:   return (0);
1.164     brouard  9199:  /* endread:*/
1.136     brouard  9200:     printf("Exiting calandcheckages: ");
                   9201:     return (1);
                   9202: }
                   9203: 
1.172     brouard  9204: #if defined(_MSC_VER)
                   9205: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9206: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9207: //#include "stdafx.h"
                   9208: //#include <stdio.h>
                   9209: //#include <tchar.h>
                   9210: //#include <windows.h>
                   9211: //#include <iostream>
                   9212: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9213: 
                   9214: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9215: 
                   9216: BOOL IsWow64()
                   9217: {
                   9218:        BOOL bIsWow64 = FALSE;
                   9219: 
                   9220:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9221:        //  (HANDLE, PBOOL);
                   9222: 
                   9223:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9224: 
                   9225:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9226:        const char funcName[] = "IsWow64Process";
                   9227:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9228:                GetProcAddress(module, funcName);
                   9229: 
                   9230:        if (NULL != fnIsWow64Process)
                   9231:        {
                   9232:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9233:                        &bIsWow64))
                   9234:                        //throw std::exception("Unknown error");
                   9235:                        printf("Unknown error\n");
                   9236:        }
                   9237:        return bIsWow64 != FALSE;
                   9238: }
                   9239: #endif
1.177     brouard  9240: 
1.191     brouard  9241: void syscompilerinfo(int logged)
1.167     brouard  9242:  {
                   9243:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9244:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9245:    /* /GS /W3 /Gy
                   9246:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9247:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9248:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9249:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9250:    */ 
                   9251:    /* 64 bits */
1.185     brouard  9252:    /*
                   9253:      /GS /W3 /Gy
                   9254:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9255:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9256:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9257:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9258:    /* Optimization are useless and O3 is slower than O2 */
                   9259:    /*
                   9260:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9261:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9262:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9263:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9264:    */
1.186     brouard  9265:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9266:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9267:       /PDB:"visual studio
                   9268:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9269:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9270:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9271:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9272:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9273:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9274:       uiAccess='false'"
                   9275:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9276:       /NOLOGO /TLBID:1
                   9277:    */
1.177     brouard  9278: #if defined __INTEL_COMPILER
1.178     brouard  9279: #if defined(__GNUC__)
                   9280:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9281: #endif
1.177     brouard  9282: #elif defined(__GNUC__) 
1.179     brouard  9283: #ifndef  __APPLE__
1.174     brouard  9284: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9285: #endif
1.177     brouard  9286:    struct utsname sysInfo;
1.178     brouard  9287:    int cross = CROSS;
                   9288:    if (cross){
                   9289:           printf("Cross-");
1.191     brouard  9290:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9291:    }
1.174     brouard  9292: #endif
                   9293: 
1.171     brouard  9294: #include <stdint.h>
1.178     brouard  9295: 
1.191     brouard  9296:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9297: #if defined(__clang__)
1.191     brouard  9298:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9299: #endif
                   9300: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9301:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9302: #endif
                   9303: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9304:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9305: #endif
                   9306: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9307:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9308: #endif
                   9309: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9310:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9311: #endif
                   9312: #if defined(_MSC_VER)
1.191     brouard  9313:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9314: #endif
                   9315: #if defined(__PGI)
1.191     brouard  9316:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9317: #endif
                   9318: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9319:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9320: #endif
1.191     brouard  9321:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9322:    
1.167     brouard  9323: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9324: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9325:     // Windows (x64 and x86)
1.191     brouard  9326:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9327: #elif __unix__ // all unices, not all compilers
                   9328:     // Unix
1.191     brouard  9329:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9330: #elif __linux__
                   9331:     // linux
1.191     brouard  9332:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9333: #elif __APPLE__
1.174     brouard  9334:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9335:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9336: #endif
                   9337: 
                   9338: /*  __MINGW32__          */
                   9339: /*  __CYGWIN__  */
                   9340: /* __MINGW64__  */
                   9341: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9342: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9343: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9344: /* _WIN64  // Defined for applications for Win64. */
                   9345: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9346: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9347: 
1.167     brouard  9348: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9349:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9350: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9351:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9352: #else
1.191     brouard  9353:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9354: #endif
                   9355: 
1.169     brouard  9356: #if defined(__GNUC__)
                   9357: # if defined(__GNUC_PATCHLEVEL__)
                   9358: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9359:                             + __GNUC_MINOR__ * 100 \
                   9360:                             + __GNUC_PATCHLEVEL__)
                   9361: # else
                   9362: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9363:                             + __GNUC_MINOR__ * 100)
                   9364: # endif
1.174     brouard  9365:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9366:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9367: 
                   9368:    if (uname(&sysInfo) != -1) {
                   9369:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9370:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9371:    }
                   9372:    else
                   9373:       perror("uname() error");
1.179     brouard  9374:    //#ifndef __INTEL_COMPILER 
                   9375: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9376:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9377:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9378: #endif
1.169     brouard  9379: #endif
1.172     brouard  9380: 
                   9381:    //   void main()
                   9382:    //   {
1.169     brouard  9383: #if defined(_MSC_VER)
1.174     brouard  9384:    if (IsWow64()){
1.191     brouard  9385:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9386:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9387:    }
                   9388:    else{
1.191     brouard  9389:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9390:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9391:    }
1.172     brouard  9392:    //     printf("\nPress Enter to continue...");
                   9393:    //     getchar();
                   9394:    //   }
                   9395: 
1.169     brouard  9396: #endif
                   9397:    
1.167     brouard  9398: 
1.219     brouard  9399: }
1.136     brouard  9400: 
1.219     brouard  9401: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9402:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9403:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9404:   /* double ftolpl = 1.e-10; */
1.180     brouard  9405:   double age, agebase, agelim;
1.203     brouard  9406:   double tot;
1.180     brouard  9407: 
1.202     brouard  9408:   strcpy(filerespl,"PL_");
                   9409:   strcat(filerespl,fileresu);
                   9410:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9411:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9412:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9413:   }
1.227     brouard  9414:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9415:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9416:   pstamp(ficrespl);
1.203     brouard  9417:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9418:   fprintf(ficrespl,"#Age ");
                   9419:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9420:   fprintf(ficrespl,"\n");
1.180     brouard  9421:   
1.219     brouard  9422:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9423: 
1.219     brouard  9424:   agebase=ageminpar;
                   9425:   agelim=agemaxpar;
1.180     brouard  9426: 
1.227     brouard  9427:   /* i1=pow(2,ncoveff); */
1.234     brouard  9428:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9429:   if (cptcovn < 1){i1=1;}
1.180     brouard  9430: 
1.238     brouard  9431:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9432:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9433:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9434:        continue;
1.235     brouard  9435: 
1.238     brouard  9436:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9437:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9438:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9439:       /* k=k+1; */
                   9440:       /* to clean */
                   9441:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9442:       fprintf(ficrespl,"#******");
                   9443:       printf("#******");
                   9444:       fprintf(ficlog,"#******");
                   9445:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9446:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9447:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9448:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9449:       }
                   9450:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9451:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9452:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9453:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9454:       }
                   9455:       fprintf(ficrespl,"******\n");
                   9456:       printf("******\n");
                   9457:       fprintf(ficlog,"******\n");
                   9458:       if(invalidvarcomb[k]){
                   9459:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9460:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9461:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9462:        continue;
                   9463:       }
1.219     brouard  9464: 
1.238     brouard  9465:       fprintf(ficrespl,"#Age ");
                   9466:       for(j=1;j<=cptcoveff;j++) {
                   9467:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9468:       }
                   9469:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9470:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9471:     
1.238     brouard  9472:       for (age=agebase; age<=agelim; age++){
                   9473:        /* for (age=agebase; age<=agebase; age++){ */
                   9474:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9475:        fprintf(ficrespl,"%.0f ",age );
                   9476:        for(j=1;j<=cptcoveff;j++)
                   9477:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9478:        tot=0.;
                   9479:        for(i=1; i<=nlstate;i++){
                   9480:          tot +=  prlim[i][i];
                   9481:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9482:        }
                   9483:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9484:       } /* Age */
                   9485:       /* was end of cptcod */
                   9486:     } /* cptcov */
                   9487:   } /* nres */
1.219     brouard  9488:   return 0;
1.180     brouard  9489: }
                   9490: 
1.218     brouard  9491: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9492:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9493:        
                   9494:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9495:    * at any age between ageminpar and agemaxpar
                   9496:         */
1.235     brouard  9497:   int i, j, k, i1, nres=0 ;
1.217     brouard  9498:   /* double ftolpl = 1.e-10; */
                   9499:   double age, agebase, agelim;
                   9500:   double tot;
1.218     brouard  9501:   /* double ***mobaverage; */
                   9502:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9503: 
                   9504:   strcpy(fileresplb,"PLB_");
                   9505:   strcat(fileresplb,fileresu);
                   9506:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9507:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9508:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9509:   }
                   9510:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9511:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9512:   pstamp(ficresplb);
                   9513:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9514:   fprintf(ficresplb,"#Age ");
                   9515:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9516:   fprintf(ficresplb,"\n");
                   9517:   
1.218     brouard  9518:   
                   9519:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9520:   
                   9521:   agebase=ageminpar;
                   9522:   agelim=agemaxpar;
                   9523:   
                   9524:   
1.227     brouard  9525:   i1=pow(2,cptcoveff);
1.218     brouard  9526:   if (cptcovn < 1){i1=1;}
1.227     brouard  9527:   
1.238     brouard  9528:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9529:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9530:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9531:        continue;
                   9532:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9533:       fprintf(ficresplb,"#******");
                   9534:       printf("#******");
                   9535:       fprintf(ficlog,"#******");
                   9536:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9537:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9538:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9539:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9540:       }
                   9541:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9542:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9543:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9544:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9545:       }
                   9546:       fprintf(ficresplb,"******\n");
                   9547:       printf("******\n");
                   9548:       fprintf(ficlog,"******\n");
                   9549:       if(invalidvarcomb[k]){
                   9550:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9551:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9552:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9553:        continue;
                   9554:       }
1.218     brouard  9555:     
1.238     brouard  9556:       fprintf(ficresplb,"#Age ");
                   9557:       for(j=1;j<=cptcoveff;j++) {
                   9558:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9559:       }
                   9560:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9561:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9562:     
                   9563:     
1.238     brouard  9564:       for (age=agebase; age<=agelim; age++){
                   9565:        /* for (age=agebase; age<=agebase; age++){ */
                   9566:        if(mobilavproj > 0){
                   9567:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9568:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9569:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9570:        }else if (mobilavproj == 0){
                   9571:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9572:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9573:          exit(1);
                   9574:        }else{
                   9575:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9576:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9577:        }
                   9578:        fprintf(ficresplb,"%.0f ",age );
                   9579:        for(j=1;j<=cptcoveff;j++)
                   9580:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9581:        tot=0.;
                   9582:        for(i=1; i<=nlstate;i++){
                   9583:          tot +=  bprlim[i][i];
                   9584:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9585:        }
                   9586:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9587:       } /* Age */
                   9588:       /* was end of cptcod */
1.255     brouard  9589:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9590:     } /* end of any combination */
                   9591:   } /* end of nres */  
1.218     brouard  9592:   /* hBijx(p, bage, fage); */
                   9593:   /* fclose(ficrespijb); */
                   9594:   
                   9595:   return 0;
1.217     brouard  9596: }
1.218     brouard  9597:  
1.180     brouard  9598: int hPijx(double *p, int bage, int fage){
                   9599:     /*------------- h Pij x at various ages ------------*/
                   9600: 
                   9601:   int stepsize;
                   9602:   int agelim;
                   9603:   int hstepm;
                   9604:   int nhstepm;
1.235     brouard  9605:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9606: 
                   9607:   double agedeb;
                   9608:   double ***p3mat;
                   9609: 
1.201     brouard  9610:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9611:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9612:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9613:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9614:     }
                   9615:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9616:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9617:   
                   9618:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9619:     /*if (stepm<=24) stepsize=2;*/
                   9620: 
                   9621:     agelim=AGESUP;
                   9622:     hstepm=stepsize*YEARM; /* Every year of age */
                   9623:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9624:                
1.180     brouard  9625:     /* hstepm=1;   aff par mois*/
                   9626:     pstamp(ficrespij);
                   9627:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9628:     i1= pow(2,cptcoveff);
1.218     brouard  9629:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9630:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9631:                /*      k=k+1;  */
1.235     brouard  9632:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9633:     for(k=1; k<=i1;k++){
1.253     brouard  9634:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9635:        continue;
1.183     brouard  9636:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9637:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9638:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9639:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9640:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9641:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9642:       }
1.183     brouard  9643:       fprintf(ficrespij,"******\n");
                   9644:       
                   9645:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9646:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9647:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9648:        
                   9649:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9650:        
1.183     brouard  9651:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9652:        oldm=oldms;savm=savms;
1.235     brouard  9653:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9654:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9655:        for(i=1; i<=nlstate;i++)
                   9656:          for(j=1; j<=nlstate+ndeath;j++)
                   9657:            fprintf(ficrespij," %1d-%1d",i,j);
                   9658:        fprintf(ficrespij,"\n");
                   9659:        for (h=0; h<=nhstepm; h++){
                   9660:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9661:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9662:          for(i=1; i<=nlstate;i++)
                   9663:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9664:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9665:          fprintf(ficrespij,"\n");
                   9666:        }
1.183     brouard  9667:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9668:        fprintf(ficrespij,"\n");
                   9669:       }
1.180     brouard  9670:       /*}*/
                   9671:     }
1.218     brouard  9672:     return 0;
1.180     brouard  9673: }
1.218     brouard  9674:  
                   9675:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9676:     /*------------- h Bij x at various ages ------------*/
                   9677: 
                   9678:   int stepsize;
1.218     brouard  9679:   /* int agelim; */
                   9680:        int ageminl;
1.217     brouard  9681:   int hstepm;
                   9682:   int nhstepm;
1.238     brouard  9683:   int h, i, i1, j, k, nres;
1.218     brouard  9684:        
1.217     brouard  9685:   double agedeb;
                   9686:   double ***p3mat;
1.218     brouard  9687:        
                   9688:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9689:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9690:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9691:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9692:   }
                   9693:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9694:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9695:   
                   9696:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9697:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9698:   
1.218     brouard  9699:   /* agelim=AGESUP; */
                   9700:   ageminl=30;
                   9701:   hstepm=stepsize*YEARM; /* Every year of age */
                   9702:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9703:   
                   9704:   /* hstepm=1;   aff par mois*/
                   9705:   pstamp(ficrespijb);
1.255     brouard  9706:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9707:   i1= pow(2,cptcoveff);
1.218     brouard  9708:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9709:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9710:   /*   k=k+1;  */
1.238     brouard  9711:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9712:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9713:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9714:        continue;
                   9715:       fprintf(ficrespijb,"\n#****** ");
                   9716:       for(j=1;j<=cptcoveff;j++)
                   9717:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9718:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9719:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9720:       }
                   9721:       fprintf(ficrespijb,"******\n");
                   9722:       if(invalidvarcomb[k]){
                   9723:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9724:        continue;
                   9725:       }
                   9726:       
                   9727:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9728:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9729:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9730:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9731:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9732:        
                   9733:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9734:        
                   9735:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9736:        /* oldm=oldms;savm=savms; */
                   9737:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9738:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9739:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9740:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9741:        for(i=1; i<=nlstate;i++)
                   9742:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9743:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9744:        fprintf(ficrespijb,"\n");
1.238     brouard  9745:        for (h=0; h<=nhstepm; h++){
                   9746:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9747:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9748:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9749:          for(i=1; i<=nlstate;i++)
                   9750:            for(j=1; j<=nlstate+ndeath;j++)
                   9751:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9752:          fprintf(ficrespijb,"\n");
                   9753:        }
                   9754:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9755:        fprintf(ficrespijb,"\n");
                   9756:       } /* end age deb */
                   9757:     } /* end combination */
                   9758:   } /* end nres */
1.218     brouard  9759:   return 0;
                   9760:  } /*  hBijx */
1.217     brouard  9761: 
1.180     brouard  9762: 
1.136     brouard  9763: /***********************************************/
                   9764: /**************** Main Program *****************/
                   9765: /***********************************************/
                   9766: 
                   9767: int main(int argc, char *argv[])
                   9768: {
                   9769: #ifdef GSL
                   9770:   const gsl_multimin_fminimizer_type *T;
                   9771:   size_t iteri = 0, it;
                   9772:   int rval = GSL_CONTINUE;
                   9773:   int status = GSL_SUCCESS;
                   9774:   double ssval;
                   9775: #endif
                   9776:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9777:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9778:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9779:   int jj, ll, li, lj, lk;
1.136     brouard  9780:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9781:   int num_filled;
1.136     brouard  9782:   int itimes;
                   9783:   int NDIM=2;
                   9784:   int vpopbased=0;
1.235     brouard  9785:   int nres=0;
1.258     brouard  9786:   int endishere=0;
1.136     brouard  9787: 
1.164     brouard  9788:   char ca[32], cb[32];
1.136     brouard  9789:   /*  FILE *fichtm; *//* Html File */
                   9790:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9791:   struct stat info;
1.191     brouard  9792:   double agedeb=0.;
1.194     brouard  9793: 
                   9794:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9795:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9796: 
1.165     brouard  9797:   double fret;
1.191     brouard  9798:   double dum=0.; /* Dummy variable */
1.136     brouard  9799:   double ***p3mat;
1.218     brouard  9800:   /* double ***mobaverage; */
1.164     brouard  9801: 
                   9802:   char line[MAXLINE];
1.197     brouard  9803:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9804: 
1.234     brouard  9805:   char  modeltemp[MAXLINE];
1.230     brouard  9806:   char resultline[MAXLINE];
                   9807:   
1.136     brouard  9808:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9809:   char *tok, *val; /* pathtot */
1.136     brouard  9810:   int firstobs=1, lastobs=10;
1.195     brouard  9811:   int c,  h , cpt, c2;
1.191     brouard  9812:   int jl=0;
                   9813:   int i1, j1, jk, stepsize=0;
1.194     brouard  9814:   int count=0;
                   9815: 
1.164     brouard  9816:   int *tab; 
1.136     brouard  9817:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9818:   int backcast=0;
1.136     brouard  9819:   int mobilav=0,popforecast=0;
1.191     brouard  9820:   int hstepm=0, nhstepm=0;
1.136     brouard  9821:   int agemortsup;
                   9822:   float  sumlpop=0.;
                   9823:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9824:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9825: 
1.191     brouard  9826:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9827:   double ftolpl=FTOL;
                   9828:   double **prlim;
1.217     brouard  9829:   double **bprlim;
1.136     brouard  9830:   double ***param; /* Matrix of parameters */
1.251     brouard  9831:   double ***paramstart; /* Matrix of starting parameter values */
                   9832:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9833:   double **matcov; /* Matrix of covariance */
1.203     brouard  9834:   double **hess; /* Hessian matrix */
1.136     brouard  9835:   double ***delti3; /* Scale */
                   9836:   double *delti; /* Scale */
                   9837:   double ***eij, ***vareij;
                   9838:   double **varpl; /* Variances of prevalence limits by age */
                   9839:   double *epj, vepp;
1.164     brouard  9840: 
1.136     brouard  9841:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9842:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9843: 
1.136     brouard  9844:   double **ximort;
1.145     brouard  9845:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9846:   int *dcwave;
                   9847: 
1.164     brouard  9848:   char z[1]="c";
1.136     brouard  9849: 
                   9850:   /*char  *strt;*/
                   9851:   char strtend[80];
1.126     brouard  9852: 
1.164     brouard  9853: 
1.126     brouard  9854: /*   setlocale (LC_ALL, ""); */
                   9855: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9856: /*   textdomain (PACKAGE); */
                   9857: /*   setlocale (LC_CTYPE, ""); */
                   9858: /*   setlocale (LC_MESSAGES, ""); */
                   9859: 
                   9860:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9861:   rstart_time = time(NULL);  
                   9862:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9863:   start_time = *localtime(&rstart_time);
1.126     brouard  9864:   curr_time=start_time;
1.157     brouard  9865:   /*tml = *localtime(&start_time.tm_sec);*/
                   9866:   /* strcpy(strstart,asctime(&tml)); */
                   9867:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9868: 
                   9869: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9870: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9871: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9872: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9873: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9874: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9875: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9876: /*   strt=asctime(&tmg); */
                   9877: /*   printf("Time(after) =%s",strstart);  */
                   9878: /*  (void) time (&time_value);
                   9879: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9880: *  tm = *localtime(&time_value);
                   9881: *  strstart=asctime(&tm);
                   9882: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9883: */
                   9884: 
                   9885:   nberr=0; /* Number of errors and warnings */
                   9886:   nbwarn=0;
1.184     brouard  9887: #ifdef WIN32
                   9888:   _getcwd(pathcd, size);
                   9889: #else
1.126     brouard  9890:   getcwd(pathcd, size);
1.184     brouard  9891: #endif
1.191     brouard  9892:   syscompilerinfo(0);
1.196     brouard  9893:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9894:   if(argc <=1){
                   9895:     printf("\nEnter the parameter file name: ");
1.205     brouard  9896:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9897:       printf("ERROR Empty parameter file name\n");
                   9898:       goto end;
                   9899:     }
1.126     brouard  9900:     i=strlen(pathr);
                   9901:     if(pathr[i-1]=='\n')
                   9902:       pathr[i-1]='\0';
1.156     brouard  9903:     i=strlen(pathr);
1.205     brouard  9904:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9905:       pathr[i-1]='\0';
1.205     brouard  9906:     }
                   9907:     i=strlen(pathr);
                   9908:     if( i==0 ){
                   9909:       printf("ERROR Empty parameter file name\n");
                   9910:       goto end;
                   9911:     }
                   9912:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9913:       printf("Pathr |%s|\n",pathr);
                   9914:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9915:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9916:       strcpy (pathtot, val);
                   9917:       if(pathr[0] == '\0') break; /* Dirty */
                   9918:     }
                   9919:   }
                   9920:   else{
                   9921:     strcpy(pathtot,argv[1]);
                   9922:   }
                   9923:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9924:   /*cygwin_split_path(pathtot,path,optionfile);
                   9925:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9926:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9927: 
                   9928:   /* Split argv[0], imach program to get pathimach */
                   9929:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9930:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9931:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9932:  /*   strcpy(pathimach,argv[0]); */
                   9933:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9934:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9935:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9936: #ifdef WIN32
                   9937:   _chdir(path); /* Can be a relative path */
                   9938:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9939: #else
1.126     brouard  9940:   chdir(path); /* Can be a relative path */
1.184     brouard  9941:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9942: #endif
                   9943:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9944:   strcpy(command,"mkdir ");
                   9945:   strcat(command,optionfilefiname);
                   9946:   if((outcmd=system(command)) != 0){
1.169     brouard  9947:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9948:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9949:     /* fclose(ficlog); */
                   9950: /*     exit(1); */
                   9951:   }
                   9952: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9953: /*     perror("mkdir"); */
                   9954: /*   } */
                   9955: 
                   9956:   /*-------- arguments in the command line --------*/
                   9957: 
1.186     brouard  9958:   /* Main Log file */
1.126     brouard  9959:   strcat(filelog, optionfilefiname);
                   9960:   strcat(filelog,".log");    /* */
                   9961:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9962:     printf("Problem with logfile %s\n",filelog);
                   9963:     goto end;
                   9964:   }
                   9965:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9966:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9967:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9968:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9969:  path=%s \n\
                   9970:  optionfile=%s\n\
                   9971:  optionfilext=%s\n\
1.156     brouard  9972:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9973: 
1.197     brouard  9974:   syscompilerinfo(1);
1.167     brouard  9975: 
1.126     brouard  9976:   printf("Local time (at start):%s",strstart);
                   9977:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9978:   fflush(ficlog);
                   9979: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9980: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9981: 
                   9982:   /* */
                   9983:   strcpy(fileres,"r");
                   9984:   strcat(fileres, optionfilefiname);
1.201     brouard  9985:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9986:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9987:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9988: 
1.186     brouard  9989:   /* Main ---------arguments file --------*/
1.126     brouard  9990: 
                   9991:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9992:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9993:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9994:     fflush(ficlog);
1.149     brouard  9995:     /* goto end; */
                   9996:     exit(70); 
1.126     brouard  9997:   }
                   9998: 
                   9999: 
                   10000: 
                   10001:   strcpy(filereso,"o");
1.201     brouard  10002:   strcat(filereso,fileresu);
1.126     brouard  10003:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10004:     printf("Problem with Output resultfile: %s\n", filereso);
                   10005:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10006:     fflush(ficlog);
                   10007:     goto end;
                   10008:   }
                   10009: 
                   10010:   /* Reads comments: lines beginning with '#' */
                   10011:   numlinepar=0;
1.197     brouard  10012: 
                   10013:     /* First parameter line */
                   10014:   while(fgets(line, MAXLINE, ficpar)) {
                   10015:     /* If line starts with a # it is a comment */
                   10016:     if (line[0] == '#') {
                   10017:       numlinepar++;
                   10018:       fputs(line,stdout);
                   10019:       fputs(line,ficparo);
                   10020:       fputs(line,ficlog);
                   10021:       continue;
                   10022:     }else
                   10023:       break;
                   10024:   }
                   10025:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10026:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10027:     if (num_filled != 5) {
                   10028:       printf("Should be 5 parameters\n");
                   10029:     }
1.126     brouard  10030:     numlinepar++;
1.197     brouard  10031:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10032:   }
                   10033:   /* Second parameter line */
                   10034:   while(fgets(line, MAXLINE, ficpar)) {
                   10035:     /* If line starts with a # it is a comment */
                   10036:     if (line[0] == '#') {
                   10037:       numlinepar++;
                   10038:       fputs(line,stdout);
                   10039:       fputs(line,ficparo);
                   10040:       fputs(line,ficlog);
                   10041:       continue;
                   10042:     }else
                   10043:       break;
                   10044:   }
1.223     brouard  10045:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10046:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10047:     if (num_filled != 11) {
                   10048:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10049:       printf("but line=%s\n",line);
1.197     brouard  10050:     }
1.223     brouard  10051:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10052:   }
1.203     brouard  10053:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10054:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10055:   /* Third parameter line */
                   10056:   while(fgets(line, MAXLINE, ficpar)) {
                   10057:     /* If line starts with a # it is a comment */
                   10058:     if (line[0] == '#') {
                   10059:       numlinepar++;
                   10060:       fputs(line,stdout);
                   10061:       fputs(line,ficparo);
                   10062:       fputs(line,ficlog);
                   10063:       continue;
                   10064:     }else
                   10065:       break;
                   10066:   }
1.201     brouard  10067:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10068:     if (num_filled == 0)
                   10069:             model[0]='\0';
                   10070:     else if (num_filled != 1){
1.197     brouard  10071:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10072:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10073:       model[0]='\0';
                   10074:       goto end;
                   10075:     }
                   10076:     else{
                   10077:       if (model[0]=='+'){
                   10078:        for(i=1; i<=strlen(model);i++)
                   10079:          modeltemp[i-1]=model[i];
1.201     brouard  10080:        strcpy(model,modeltemp); 
1.197     brouard  10081:       }
                   10082:     }
1.199     brouard  10083:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10084:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10085:   }
                   10086:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10087:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10088:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10089:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10090:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10091:   fflush(ficlog);
1.190     brouard  10092:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10093:   if(model[0]=='#'){
1.187     brouard  10094:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10095:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10096:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10097:     if(mle != -1){
                   10098:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10099:       exit(1);
                   10100:     }
                   10101:   }
1.126     brouard  10102:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10103:     ungetc(c,ficpar);
                   10104:     fgets(line, MAXLINE, ficpar);
                   10105:     numlinepar++;
1.195     brouard  10106:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10107:       z[0]=line[1];
                   10108:     }
                   10109:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10110:     fputs(line, stdout);
                   10111:     //puts(line);
1.126     brouard  10112:     fputs(line,ficparo);
                   10113:     fputs(line,ficlog);
                   10114:   }
                   10115:   ungetc(c,ficpar);
                   10116: 
                   10117:    
1.145     brouard  10118:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10119:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10120:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10121:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10122:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10123:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10124:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10125:   */
                   10126:   if (strlen(model)>1) 
1.187     brouard  10127:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10128:   else
1.187     brouard  10129:     ncovmodel=2; /* Constant and age */
1.133     brouard  10130:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10131:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10132:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10133:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10134:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10135:     fflush(stdout);
                   10136:     fclose (ficlog);
                   10137:     goto end;
                   10138:   }
1.126     brouard  10139:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10140:   delti=delti3[1][1];
                   10141:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10142:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10143: /* We could also provide initial parameters values giving by simple logistic regression 
                   10144:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10145:       /* for(i=1;i<nlstate;i++){ */
                   10146:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10147:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10148:       /* } */
1.126     brouard  10149:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10150:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10151:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10152:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10153:     fclose (ficparo);
                   10154:     fclose (ficlog);
                   10155:     goto end;
                   10156:     exit(0);
1.220     brouard  10157:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10158:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10159:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10160:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10161:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10162:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10163:     hess=matrix(1,npar,1,npar);
1.220     brouard  10164:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10165:     /* Read guessed parameters */
1.126     brouard  10166:     /* Reads comments: lines beginning with '#' */
                   10167:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10168:       ungetc(c,ficpar);
                   10169:       fgets(line, MAXLINE, ficpar);
                   10170:       numlinepar++;
1.141     brouard  10171:       fputs(line,stdout);
1.126     brouard  10172:       fputs(line,ficparo);
                   10173:       fputs(line,ficlog);
                   10174:     }
                   10175:     ungetc(c,ficpar);
                   10176:     
                   10177:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10178:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10179:     for(i=1; i <=nlstate; i++){
1.234     brouard  10180:       j=0;
1.126     brouard  10181:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10182:        if(jj==i) continue;
                   10183:        j++;
                   10184:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10185:        if ((i1 != i) || (j1 != jj)){
                   10186:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10187: It might be a problem of design; if ncovcol and the model are correct\n \
                   10188: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10189:          exit(1);
                   10190:        }
                   10191:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10192:        if(mle==1)
                   10193:          printf("%1d%1d",i,jj);
                   10194:        fprintf(ficlog,"%1d%1d",i,jj);
                   10195:        for(k=1; k<=ncovmodel;k++){
                   10196:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10197:          if(mle==1){
                   10198:            printf(" %lf",param[i][j][k]);
                   10199:            fprintf(ficlog," %lf",param[i][j][k]);
                   10200:          }
                   10201:          else
                   10202:            fprintf(ficlog," %lf",param[i][j][k]);
                   10203:          fprintf(ficparo," %lf",param[i][j][k]);
                   10204:        }
                   10205:        fscanf(ficpar,"\n");
                   10206:        numlinepar++;
                   10207:        if(mle==1)
                   10208:          printf("\n");
                   10209:        fprintf(ficlog,"\n");
                   10210:        fprintf(ficparo,"\n");
1.126     brouard  10211:       }
                   10212:     }  
                   10213:     fflush(ficlog);
1.234     brouard  10214:     
1.251     brouard  10215:     /* Reads parameters values */
1.126     brouard  10216:     p=param[1][1];
1.251     brouard  10217:     pstart=paramstart[1][1];
1.126     brouard  10218:     
                   10219:     /* Reads comments: lines beginning with '#' */
                   10220:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10221:       ungetc(c,ficpar);
                   10222:       fgets(line, MAXLINE, ficpar);
                   10223:       numlinepar++;
1.141     brouard  10224:       fputs(line,stdout);
1.126     brouard  10225:       fputs(line,ficparo);
                   10226:       fputs(line,ficlog);
                   10227:     }
                   10228:     ungetc(c,ficpar);
                   10229: 
                   10230:     for(i=1; i <=nlstate; i++){
                   10231:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10232:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10233:        if ( (i1-i) * (j1-j) != 0){
                   10234:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10235:          exit(1);
                   10236:        }
                   10237:        printf("%1d%1d",i,j);
                   10238:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10239:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10240:        for(k=1; k<=ncovmodel;k++){
                   10241:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10242:          printf(" %le",delti3[i][j][k]);
                   10243:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10244:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10245:        }
                   10246:        fscanf(ficpar,"\n");
                   10247:        numlinepar++;
                   10248:        printf("\n");
                   10249:        fprintf(ficparo,"\n");
                   10250:        fprintf(ficlog,"\n");
1.126     brouard  10251:       }
                   10252:     }
                   10253:     fflush(ficlog);
1.234     brouard  10254:     
1.145     brouard  10255:     /* Reads covariance matrix */
1.126     brouard  10256:     delti=delti3[1][1];
1.220     brouard  10257:                
                   10258:                
1.126     brouard  10259:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10260:                
1.126     brouard  10261:     /* Reads comments: lines beginning with '#' */
                   10262:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10263:       ungetc(c,ficpar);
                   10264:       fgets(line, MAXLINE, ficpar);
                   10265:       numlinepar++;
1.141     brouard  10266:       fputs(line,stdout);
1.126     brouard  10267:       fputs(line,ficparo);
                   10268:       fputs(line,ficlog);
                   10269:     }
                   10270:     ungetc(c,ficpar);
1.220     brouard  10271:                
1.126     brouard  10272:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10273:     hess=matrix(1,npar,1,npar);
1.131     brouard  10274:     for(i=1; i <=npar; i++)
                   10275:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10276:                
1.194     brouard  10277:     /* Scans npar lines */
1.126     brouard  10278:     for(i=1; i <=npar; i++){
1.226     brouard  10279:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10280:       if(count != 3){
1.226     brouard  10281:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10282: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10283: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10284:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10285: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10286: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10287:        exit(1);
1.220     brouard  10288:       }else{
1.226     brouard  10289:        if(mle==1)
                   10290:          printf("%1d%1d%d",i1,j1,jk);
                   10291:       }
                   10292:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10293:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10294:       for(j=1; j <=i; j++){
1.226     brouard  10295:        fscanf(ficpar," %le",&matcov[i][j]);
                   10296:        if(mle==1){
                   10297:          printf(" %.5le",matcov[i][j]);
                   10298:        }
                   10299:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10300:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10301:       }
                   10302:       fscanf(ficpar,"\n");
                   10303:       numlinepar++;
                   10304:       if(mle==1)
1.220     brouard  10305:                                printf("\n");
1.126     brouard  10306:       fprintf(ficlog,"\n");
                   10307:       fprintf(ficparo,"\n");
                   10308:     }
1.194     brouard  10309:     /* End of read covariance matrix npar lines */
1.126     brouard  10310:     for(i=1; i <=npar; i++)
                   10311:       for(j=i+1;j<=npar;j++)
1.226     brouard  10312:        matcov[i][j]=matcov[j][i];
1.126     brouard  10313:     
                   10314:     if(mle==1)
                   10315:       printf("\n");
                   10316:     fprintf(ficlog,"\n");
                   10317:     
                   10318:     fflush(ficlog);
                   10319:     
                   10320:     /*-------- Rewriting parameter file ----------*/
                   10321:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10322:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10323:     strcat(rfileres,".");    /* */
                   10324:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10325:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10326:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10327:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10328:     }
                   10329:     fprintf(ficres,"#%s\n",version);
                   10330:   }    /* End of mle != -3 */
1.218     brouard  10331:   
1.186     brouard  10332:   /*  Main data
                   10333:    */
1.126     brouard  10334:   n= lastobs;
                   10335:   num=lvector(1,n);
                   10336:   moisnais=vector(1,n);
                   10337:   annais=vector(1,n);
                   10338:   moisdc=vector(1,n);
                   10339:   andc=vector(1,n);
1.220     brouard  10340:   weight=vector(1,n);
1.126     brouard  10341:   agedc=vector(1,n);
                   10342:   cod=ivector(1,n);
1.220     brouard  10343:   for(i=1;i<=n;i++){
1.234     brouard  10344:     num[i]=0;
                   10345:     moisnais[i]=0;
                   10346:     annais[i]=0;
                   10347:     moisdc[i]=0;
                   10348:     andc[i]=0;
                   10349:     agedc[i]=0;
                   10350:     cod[i]=0;
                   10351:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10352:   }
1.126     brouard  10353:   mint=matrix(1,maxwav,1,n);
                   10354:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10355:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10356:   tab=ivector(1,NCOVMAX);
1.144     brouard  10357:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10358:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10359: 
1.136     brouard  10360:   /* Reads data from file datafile */
                   10361:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10362:     goto end;
                   10363: 
                   10364:   /* Calculation of the number of parameters from char model */
1.234     brouard  10365:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10366:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10367:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10368:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10369:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10370:   */
                   10371:   
                   10372:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10373:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10374:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10375:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10376:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10377:   TvarF=ivector(1,NCOVMAX); /*  */
                   10378:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10379:   TvarV=ivector(1,NCOVMAX); /*  */
                   10380:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10381:   TvarA=ivector(1,NCOVMAX); /*  */
                   10382:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10383:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10384:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10385:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10386:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10387:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10388:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10389:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10390:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10391: 
1.230     brouard  10392:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10393:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10394:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10395:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10396:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10397:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10398:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10399:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10400:   */
                   10401:   /* For model-covariate k tells which data-covariate to use but
                   10402:     because this model-covariate is a construction we invent a new column
                   10403:     ncovcol + k1
                   10404:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10405:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10406:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10407:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10408:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10409:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10410:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10411:   */
1.145     brouard  10412:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10413:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10414:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10415:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10416:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10417:                         4 covariates (3 plus signs)
                   10418:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10419:                      */  
1.230     brouard  10420:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10421:                                * individual dummy, fixed or varying:
                   10422:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10423:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10424:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10425:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10426:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10427:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10428:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10429:                                * individual quantitative, fixed or varying:
                   10430:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10431:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10432:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10433: /* Main decodemodel */
                   10434: 
1.187     brouard  10435: 
1.223     brouard  10436:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10437:     goto end;
                   10438: 
1.137     brouard  10439:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10440:     nbwarn++;
                   10441:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10442:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10443:   }
1.136     brouard  10444:     /*  if(mle==1){*/
1.137     brouard  10445:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10446:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10447:   }
                   10448: 
                   10449:     /*-calculation of age at interview from date of interview and age at death -*/
                   10450:   agev=matrix(1,maxwav,1,imx);
                   10451: 
                   10452:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10453:     goto end;
                   10454: 
1.126     brouard  10455: 
1.136     brouard  10456:   agegomp=(int)agemin;
                   10457:   free_vector(moisnais,1,n);
                   10458:   free_vector(annais,1,n);
1.126     brouard  10459:   /* free_matrix(mint,1,maxwav,1,n);
                   10460:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10461:   /* free_vector(moisdc,1,n); */
                   10462:   /* free_vector(andc,1,n); */
1.145     brouard  10463:   /* */
                   10464:   
1.126     brouard  10465:   wav=ivector(1,imx);
1.214     brouard  10466:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10467:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10468:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10469:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10470:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10471:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10472:    
                   10473:   /* Concatenates waves */
1.214     brouard  10474:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10475:      Death is a valid wave (if date is known).
                   10476:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10477:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10478:      and mw[mi+1][i]. dh depends on stepm.
                   10479:   */
                   10480: 
1.126     brouard  10481:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10482:   /* Concatenates waves */
1.145     brouard  10483:  
1.215     brouard  10484:   free_vector(moisdc,1,n);
                   10485:   free_vector(andc,1,n);
                   10486: 
1.126     brouard  10487:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10488:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10489:   ncodemax[1]=1;
1.145     brouard  10490:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10491:   cptcoveff=0;
1.220     brouard  10492:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10493:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10494:   }
                   10495:   
                   10496:   ncovcombmax=pow(2,cptcoveff);
                   10497:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10498:   for(i=1;i<ncovcombmax;i++)
                   10499:     invalidvarcomb[i]=0;
                   10500:   
1.211     brouard  10501:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10502:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10503:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10504:   
1.200     brouard  10505:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10506:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10507:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10508:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10509:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10510:    * (currently 0 or 1) in the data.
                   10511:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10512:    * corresponding modality (h,j).
                   10513:    */
                   10514: 
1.145     brouard  10515:   h=0;
                   10516:   /*if (cptcovn > 0) */
1.126     brouard  10517:   m=pow(2,cptcoveff);
                   10518:  
1.144     brouard  10519:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10520:           * For k=4 covariates, h goes from 1 to m=2**k
                   10521:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10522:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10523:           *     h\k   1     2     3     4
1.143     brouard  10524:           *______________________________  
                   10525:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10526:           *     2     2     1     1     1
                   10527:           *     3 i=2 1     2     1     1
                   10528:           *     4     2     2     1     1
                   10529:           *     5 i=3 1 i=2 1     2     1
                   10530:           *     6     2     1     2     1
                   10531:           *     7 i=4 1     2     2     1
                   10532:           *     8     2     2     2     1
1.197     brouard  10533:           *     9 i=5 1 i=3 1 i=2 1     2
                   10534:           *    10     2     1     1     2
                   10535:           *    11 i=6 1     2     1     2
                   10536:           *    12     2     2     1     2
                   10537:           *    13 i=7 1 i=4 1     2     2    
                   10538:           *    14     2     1     2     2
                   10539:           *    15 i=8 1     2     2     2
                   10540:           *    16     2     2     2     2
1.143     brouard  10541:           */
1.212     brouard  10542:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10543:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10544:      * and the value of each covariate?
                   10545:      * V1=1, V2=1, V3=2, V4=1 ?
                   10546:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10547:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10548:      * In order to get the real value in the data, we use nbcode
                   10549:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10550:      * We are keeping this crazy system in order to be able (in the future?) 
                   10551:      * to have more than 2 values (0 or 1) for a covariate.
                   10552:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10553:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10554:      *              bbbbbbbb
                   10555:      *              76543210     
                   10556:      *   h-1        00000101 (6-1=5)
1.219     brouard  10557:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10558:      *           &
                   10559:      *     1        00000001 (1)
1.219     brouard  10560:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10561:      *          +1= 00000001 =1 
1.211     brouard  10562:      *
                   10563:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10564:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10565:      *    >>k'            11
                   10566:      *          &   00000001
                   10567:      *            = 00000001
                   10568:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10569:      * Reverse h=6 and m=16?
                   10570:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10571:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10572:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10573:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10574:      * V3=decodtabm(14,3,2**4)=2
                   10575:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10576:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10577:      *          &1 000000001
                   10578:      *           = 000000001
                   10579:      *         +1= 000000010 =2
                   10580:      *                  2211
                   10581:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10582:      *                  V3=2
1.220     brouard  10583:                 * codtabm and decodtabm are identical
1.211     brouard  10584:      */
                   10585: 
1.145     brouard  10586: 
                   10587:  free_ivector(Ndum,-1,NCOVMAX);
                   10588: 
                   10589: 
1.126     brouard  10590:     
1.186     brouard  10591:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10592:   strcpy(optionfilegnuplot,optionfilefiname);
                   10593:   if(mle==-3)
1.201     brouard  10594:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10595:   strcat(optionfilegnuplot,".gp");
                   10596: 
                   10597:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10598:     printf("Problem with file %s",optionfilegnuplot);
                   10599:   }
                   10600:   else{
1.204     brouard  10601:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10602:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10603:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10604:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10605:   }
                   10606:   /*  fclose(ficgp);*/
1.186     brouard  10607: 
                   10608: 
                   10609:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10610: 
                   10611:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10612:   if(mle==-3)
1.201     brouard  10613:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10614:   strcat(optionfilehtm,".htm");
                   10615:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10616:     printf("Problem with %s \n",optionfilehtm);
                   10617:     exit(0);
1.126     brouard  10618:   }
                   10619: 
                   10620:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10621:   strcat(optionfilehtmcov,"-cov.htm");
                   10622:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10623:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10624:   }
                   10625:   else{
                   10626:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10627: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10628: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10629:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10630:   }
                   10631: 
1.213     brouard  10632:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10633: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10634: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10635: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10636: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10637: \n\
                   10638: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10639:  <ul><li><h4>Parameter files</h4>\n\
                   10640:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10641:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10642:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10643:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10644:  - Date and time at start: %s</ul>\n",\
                   10645:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10646:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10647:          fileres,fileres,\
                   10648:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10649:   fflush(fichtm);
                   10650: 
                   10651:   strcpy(pathr,path);
                   10652:   strcat(pathr,optionfilefiname);
1.184     brouard  10653: #ifdef WIN32
                   10654:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10655: #else
1.126     brouard  10656:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10657: #endif
                   10658:          
1.126     brouard  10659:   
1.220     brouard  10660:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10661:                 and for any valid combination of covariates
1.126     brouard  10662:      and prints on file fileres'p'. */
1.251     brouard  10663:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10664:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10665: 
                   10666:   fprintf(fichtm,"\n");
                   10667:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10668: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10669: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10670:          imx,agemin,agemax,jmin,jmax,jmean);
                   10671:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10672:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10673:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10674:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10675:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10676: 
1.126     brouard  10677:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10678:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10679:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10680: 
                   10681:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10682:   /* For mortality only */
1.126     brouard  10683:   if (mle==-3){
1.136     brouard  10684:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10685:     for(i=1;i<=NDIM;i++)
                   10686:       for(j=1;j<=NDIM;j++)
                   10687:        ximort[i][j]=0.;
1.186     brouard  10688:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10689:     cens=ivector(1,n);
                   10690:     ageexmed=vector(1,n);
                   10691:     agecens=vector(1,n);
                   10692:     dcwave=ivector(1,n);
1.223     brouard  10693:                
1.126     brouard  10694:     for (i=1; i<=imx; i++){
                   10695:       dcwave[i]=-1;
                   10696:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10697:        if (s[m][i]>nlstate) {
                   10698:          dcwave[i]=m;
                   10699:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10700:          break;
                   10701:        }
1.126     brouard  10702:     }
1.226     brouard  10703:     
1.126     brouard  10704:     for (i=1; i<=imx; i++) {
                   10705:       if (wav[i]>0){
1.226     brouard  10706:        ageexmed[i]=agev[mw[1][i]][i];
                   10707:        j=wav[i];
                   10708:        agecens[i]=1.; 
                   10709:        
                   10710:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10711:          agecens[i]=agev[mw[j][i]][i];
                   10712:          cens[i]= 1;
                   10713:        }else if (ageexmed[i]< 1) 
                   10714:          cens[i]= -1;
                   10715:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10716:          cens[i]=0 ;
1.126     brouard  10717:       }
                   10718:       else cens[i]=-1;
                   10719:     }
                   10720:     
                   10721:     for (i=1;i<=NDIM;i++) {
                   10722:       for (j=1;j<=NDIM;j++)
1.226     brouard  10723:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10724:     }
                   10725:     
1.145     brouard  10726:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10727:     /*printf("%lf %lf", p[1], p[2]);*/
                   10728:     
                   10729:     
1.136     brouard  10730: #ifdef GSL
                   10731:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10732: #else
1.126     brouard  10733:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10734: #endif
1.201     brouard  10735:     strcpy(filerespow,"POW-MORT_"); 
                   10736:     strcat(filerespow,fileresu);
1.126     brouard  10737:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10738:       printf("Problem with resultfile: %s\n", filerespow);
                   10739:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10740:     }
1.136     brouard  10741: #ifdef GSL
                   10742:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10743: #else
1.126     brouard  10744:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10745: #endif
1.126     brouard  10746:     /*  for (i=1;i<=nlstate;i++)
                   10747:        for(j=1;j<=nlstate+ndeath;j++)
                   10748:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10749:     */
                   10750:     fprintf(ficrespow,"\n");
1.136     brouard  10751: #ifdef GSL
                   10752:     /* gsl starts here */ 
                   10753:     T = gsl_multimin_fminimizer_nmsimplex;
                   10754:     gsl_multimin_fminimizer *sfm = NULL;
                   10755:     gsl_vector *ss, *x;
                   10756:     gsl_multimin_function minex_func;
                   10757: 
                   10758:     /* Initial vertex size vector */
                   10759:     ss = gsl_vector_alloc (NDIM);
                   10760:     
                   10761:     if (ss == NULL){
                   10762:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10763:     }
                   10764:     /* Set all step sizes to 1 */
                   10765:     gsl_vector_set_all (ss, 0.001);
                   10766: 
                   10767:     /* Starting point */
1.126     brouard  10768:     
1.136     brouard  10769:     x = gsl_vector_alloc (NDIM);
                   10770:     
                   10771:     if (x == NULL){
                   10772:       gsl_vector_free(ss);
                   10773:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10774:     }
                   10775:   
                   10776:     /* Initialize method and iterate */
                   10777:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10778:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10779:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10780:     gsl_vector_set(x, 0, p[1]);
                   10781:     gsl_vector_set(x, 1, p[2]);
                   10782: 
                   10783:     minex_func.f = &gompertz_f;
                   10784:     minex_func.n = NDIM;
                   10785:     minex_func.params = (void *)&p; /* ??? */
                   10786:     
                   10787:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10788:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10789:     
                   10790:     printf("Iterations beginning .....\n\n");
                   10791:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10792: 
                   10793:     iteri=0;
                   10794:     while (rval == GSL_CONTINUE){
                   10795:       iteri++;
                   10796:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10797:       
                   10798:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10799:       fflush(0);
                   10800:       
                   10801:       if (status) 
                   10802:         break;
                   10803:       
                   10804:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10805:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10806:       
                   10807:       if (rval == GSL_SUCCESS)
                   10808:         printf ("converged to a local maximum at\n");
                   10809:       
                   10810:       printf("%5d ", iteri);
                   10811:       for (it = 0; it < NDIM; it++){
                   10812:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10813:       }
                   10814:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10815:     }
                   10816:     
                   10817:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10818:     
                   10819:     gsl_vector_free(x); /* initial values */
                   10820:     gsl_vector_free(ss); /* inital step size */
                   10821:     for (it=0; it<NDIM; it++){
                   10822:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10823:       fprintf(ficrespow," %.12lf", p[it]);
                   10824:     }
                   10825:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10826: #endif
                   10827: #ifdef POWELL
                   10828:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10829: #endif  
1.126     brouard  10830:     fclose(ficrespow);
                   10831:     
1.203     brouard  10832:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10833: 
                   10834:     for(i=1; i <=NDIM; i++)
                   10835:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10836:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10837:     
                   10838:     printf("\nCovariance matrix\n ");
1.203     brouard  10839:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10840:     for(i=1; i <=NDIM; i++) {
                   10841:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10842:                                printf("%f ",matcov[i][j]);
                   10843:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10844:       }
1.203     brouard  10845:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10846:     }
                   10847:     
                   10848:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10849:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10850:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10851:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10852:     }
1.126     brouard  10853:     lsurv=vector(1,AGESUP);
                   10854:     lpop=vector(1,AGESUP);
                   10855:     tpop=vector(1,AGESUP);
                   10856:     lsurv[agegomp]=100000;
                   10857:     
                   10858:     for (k=agegomp;k<=AGESUP;k++) {
                   10859:       agemortsup=k;
                   10860:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10861:     }
                   10862:     
                   10863:     for (k=agegomp;k<agemortsup;k++)
                   10864:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10865:     
                   10866:     for (k=agegomp;k<agemortsup;k++){
                   10867:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10868:       sumlpop=sumlpop+lpop[k];
                   10869:     }
                   10870:     
                   10871:     tpop[agegomp]=sumlpop;
                   10872:     for (k=agegomp;k<(agemortsup-3);k++){
                   10873:       /*  tpop[k+1]=2;*/
                   10874:       tpop[k+1]=tpop[k]-lpop[k];
                   10875:     }
                   10876:     
                   10877:     
                   10878:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10879:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10880:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10881:     
                   10882:     
                   10883:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10884:                ageminpar=50;
                   10885:                agemaxpar=100;
1.194     brouard  10886:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10887:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10888: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10889: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10890:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10891: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10892: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10893:     }else{
                   10894:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10895:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10896:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10897:                }
1.201     brouard  10898:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10899:                     stepm, weightopt,\
                   10900:                     model,imx,p,matcov,agemortsup);
                   10901:     
                   10902:     free_vector(lsurv,1,AGESUP);
                   10903:     free_vector(lpop,1,AGESUP);
                   10904:     free_vector(tpop,1,AGESUP);
1.220     brouard  10905:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10906:     free_ivector(cens,1,n);
                   10907:     free_vector(agecens,1,n);
                   10908:     free_ivector(dcwave,1,n);
1.220     brouard  10909: #ifdef GSL
1.136     brouard  10910: #endif
1.186     brouard  10911:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10912:   /* Standard  */
                   10913:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10914:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10915:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10916:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10917:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10918:     for (k=1; k<=npar;k++)
                   10919:       printf(" %d %8.5f",k,p[k]);
                   10920:     printf("\n");
1.205     brouard  10921:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10922:       /* mlikeli uses func not funcone */
1.247     brouard  10923:       /* for(i=1;i<nlstate;i++){ */
                   10924:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10925:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10926:       /* } */
1.205     brouard  10927:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10928:     }
                   10929:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10930:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10931:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10932:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10933:     }
                   10934:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10935:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10936:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10937:     for (k=1; k<=npar;k++)
                   10938:       printf(" %d %8.5f",k,p[k]);
                   10939:     printf("\n");
                   10940:     
                   10941:     /*--------- results files --------------*/
1.224     brouard  10942:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10943:     
                   10944:     
                   10945:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10946:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10947:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10948:     for(i=1,jk=1; i <=nlstate; i++){
                   10949:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10950:        if (k != i) {
                   10951:          printf("%d%d ",i,k);
                   10952:          fprintf(ficlog,"%d%d ",i,k);
                   10953:          fprintf(ficres,"%1d%1d ",i,k);
                   10954:          for(j=1; j <=ncovmodel; j++){
                   10955:            printf("%12.7f ",p[jk]);
                   10956:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10957:            fprintf(ficres,"%12.7f ",p[jk]);
                   10958:            jk++; 
                   10959:          }
                   10960:          printf("\n");
                   10961:          fprintf(ficlog,"\n");
                   10962:          fprintf(ficres,"\n");
                   10963:        }
1.126     brouard  10964:       }
                   10965:     }
1.203     brouard  10966:     if(mle != 0){
                   10967:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10968:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10969:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10970:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10971:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10972:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10973:        for(k=1; k <=(nlstate+ndeath); k++){
                   10974:          if (k != i) {
                   10975:            printf("%d%d ",i,k);
                   10976:            fprintf(ficlog,"%d%d ",i,k);
                   10977:            for(j=1; j <=ncovmodel; j++){
                   10978:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10979:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10980:              jk++; 
                   10981:            }
                   10982:            printf("\n");
                   10983:            fprintf(ficlog,"\n");
                   10984:          }
                   10985:        }
1.193     brouard  10986:       }
1.203     brouard  10987:     } /* end of hesscov and Wald tests */
1.225     brouard  10988:     
1.203     brouard  10989:     /*  */
1.126     brouard  10990:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10991:     printf("# Scales (for hessian or gradient estimation)\n");
                   10992:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10993:     for(i=1,jk=1; i <=nlstate; i++){
                   10994:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10995:        if (j!=i) {
                   10996:          fprintf(ficres,"%1d%1d",i,j);
                   10997:          printf("%1d%1d",i,j);
                   10998:          fprintf(ficlog,"%1d%1d",i,j);
                   10999:          for(k=1; k<=ncovmodel;k++){
                   11000:            printf(" %.5e",delti[jk]);
                   11001:            fprintf(ficlog," %.5e",delti[jk]);
                   11002:            fprintf(ficres," %.5e",delti[jk]);
                   11003:            jk++;
                   11004:          }
                   11005:          printf("\n");
                   11006:          fprintf(ficlog,"\n");
                   11007:          fprintf(ficres,"\n");
                   11008:        }
1.126     brouard  11009:       }
                   11010:     }
                   11011:     
                   11012:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11013:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11014:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11015:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11016:     /* # 121 Var(a12)\n\ */
                   11017:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11018:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11019:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11020:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11021:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11022:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11023:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11024:     
                   11025:     
                   11026:     /* Just to have a covariance matrix which will be more understandable
                   11027:        even is we still don't want to manage dictionary of variables
                   11028:     */
                   11029:     for(itimes=1;itimes<=2;itimes++){
                   11030:       jj=0;
                   11031:       for(i=1; i <=nlstate; i++){
1.225     brouard  11032:        for(j=1; j <=nlstate+ndeath; j++){
                   11033:          if(j==i) continue;
                   11034:          for(k=1; k<=ncovmodel;k++){
                   11035:            jj++;
                   11036:            ca[0]= k+'a'-1;ca[1]='\0';
                   11037:            if(itimes==1){
                   11038:              if(mle>=1)
                   11039:                printf("#%1d%1d%d",i,j,k);
                   11040:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11041:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11042:            }else{
                   11043:              if(mle>=1)
                   11044:                printf("%1d%1d%d",i,j,k);
                   11045:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11046:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11047:            }
                   11048:            ll=0;
                   11049:            for(li=1;li <=nlstate; li++){
                   11050:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11051:                if(lj==li) continue;
                   11052:                for(lk=1;lk<=ncovmodel;lk++){
                   11053:                  ll++;
                   11054:                  if(ll<=jj){
                   11055:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11056:                    if(ll<jj){
                   11057:                      if(itimes==1){
                   11058:                        if(mle>=1)
                   11059:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11060:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11061:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11062:                      }else{
                   11063:                        if(mle>=1)
                   11064:                          printf(" %.5e",matcov[jj][ll]); 
                   11065:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11066:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11067:                      }
                   11068:                    }else{
                   11069:                      if(itimes==1){
                   11070:                        if(mle>=1)
                   11071:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11072:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11073:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11074:                      }else{
                   11075:                        if(mle>=1)
                   11076:                          printf(" %.7e",matcov[jj][ll]); 
                   11077:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11078:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11079:                      }
                   11080:                    }
                   11081:                  }
                   11082:                } /* end lk */
                   11083:              } /* end lj */
                   11084:            } /* end li */
                   11085:            if(mle>=1)
                   11086:              printf("\n");
                   11087:            fprintf(ficlog,"\n");
                   11088:            fprintf(ficres,"\n");
                   11089:            numlinepar++;
                   11090:          } /* end k*/
                   11091:        } /*end j */
1.126     brouard  11092:       } /* end i */
                   11093:     } /* end itimes */
                   11094:     
                   11095:     fflush(ficlog);
                   11096:     fflush(ficres);
1.225     brouard  11097:     while(fgets(line, MAXLINE, ficpar)) {
                   11098:       /* If line starts with a # it is a comment */
                   11099:       if (line[0] == '#') {
                   11100:        numlinepar++;
                   11101:        fputs(line,stdout);
                   11102:        fputs(line,ficparo);
                   11103:        fputs(line,ficlog);
                   11104:        continue;
                   11105:       }else
                   11106:        break;
                   11107:     }
                   11108:     
1.209     brouard  11109:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11110:     /*   ungetc(c,ficpar); */
                   11111:     /*   fgets(line, MAXLINE, ficpar); */
                   11112:     /*   fputs(line,stdout); */
                   11113:     /*   fputs(line,ficparo); */
                   11114:     /* } */
                   11115:     /* ungetc(c,ficpar); */
1.126     brouard  11116:     
                   11117:     estepm=0;
1.209     brouard  11118:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11119:       
                   11120:       if (num_filled != 6) {
                   11121:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11122:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11123:        goto end;
                   11124:       }
                   11125:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11126:     }
                   11127:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11128:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11129:     
1.209     brouard  11130:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11131:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11132:     if (fage <= 2) {
                   11133:       bage = ageminpar;
                   11134:       fage = agemaxpar;
                   11135:     }
                   11136:     
                   11137:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11138:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11139:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11140:                
1.186     brouard  11141:     /* Other stuffs, more or less useful */    
1.254     brouard  11142:     while(fgets(line, MAXLINE, ficpar)) {
                   11143:       /* If line starts with a # it is a comment */
                   11144:       if (line[0] == '#') {
                   11145:        numlinepar++;
                   11146:        fputs(line,stdout);
                   11147:        fputs(line,ficparo);
                   11148:        fputs(line,ficlog);
                   11149:        continue;
                   11150:       }else
                   11151:        break;
                   11152:     }
                   11153: 
                   11154:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11155:       
                   11156:       if (num_filled != 7) {
                   11157:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11158:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11159:        goto end;
                   11160:       }
                   11161:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11162:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11163:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11164:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11165:     }
1.254     brouard  11166: 
                   11167:     while(fgets(line, MAXLINE, ficpar)) {
                   11168:       /* If line starts with a # it is a comment */
                   11169:       if (line[0] == '#') {
                   11170:        numlinepar++;
                   11171:        fputs(line,stdout);
                   11172:        fputs(line,ficparo);
                   11173:        fputs(line,ficlog);
                   11174:        continue;
                   11175:       }else
                   11176:        break;
1.126     brouard  11177:     }
                   11178:     
                   11179:     
                   11180:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11181:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11182:     
1.254     brouard  11183:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11184:       if (num_filled != 1) {
                   11185:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11186:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11187:        goto end;
                   11188:       }
                   11189:       printf("pop_based=%d\n",popbased);
                   11190:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11191:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11192:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11193:     }
                   11194:      
1.258     brouard  11195:     /* Results */
                   11196:     nresult=0;
                   11197:     do{
                   11198:       if(!fgets(line, MAXLINE, ficpar)){
                   11199:        endishere=1;
                   11200:        parameterline=14;
                   11201:       }else if (line[0] == '#') {
                   11202:        /* If line starts with a # it is a comment */
1.254     brouard  11203:        numlinepar++;
                   11204:        fputs(line,stdout);
                   11205:        fputs(line,ficparo);
                   11206:        fputs(line,ficlog);
                   11207:        continue;
1.258     brouard  11208:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11209:        parameterline=11;
                   11210:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11211:        parameterline=12;
                   11212:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11213:        parameterline=13;
                   11214:       else{
                   11215:        parameterline=14;
1.254     brouard  11216:       }
1.258     brouard  11217:       switch (parameterline){ 
                   11218:       case 11:
                   11219:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11220:          if (num_filled != 8) {
                   11221:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11222:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11223:            goto end;
                   11224:          }
                   11225:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11226:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11227:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11228:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11229:          /* day and month of proj2 are not used but only year anproj2.*/
                   11230:        }
1.254     brouard  11231:        break;
1.258     brouard  11232:       case 12:
                   11233:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11234:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11235:          if (num_filled != 8) {
                   11236:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11237:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11238:            goto end;
                   11239:          }
                   11240:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11241:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11242:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11243:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11244:          /* day and month of proj2 are not used but only year anproj2.*/
                   11245:        }
1.230     brouard  11246:        break;
1.258     brouard  11247:       case 13:
                   11248:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11249:          if (num_filled == 0){
                   11250:            resultline[0]='\0';
                   11251:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11252:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11253:            break;
                   11254:          } else if (num_filled != 1){
                   11255:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11256:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11257:          }
                   11258:          nresult++; /* Sum of resultlines */
                   11259:          printf("Result %d: result=%s\n",nresult, resultline);
                   11260:          if(nresult > MAXRESULTLINES){
                   11261:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11262:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11263:            goto end;
                   11264:          }
                   11265:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11266:          fprintf(ficparo,"result: %s\n",resultline);
                   11267:          fprintf(ficres,"result: %s\n",resultline);
                   11268:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11269:          break;
1.258     brouard  11270:        case 14: 
1.259   ! brouard  11271:          if(ncovmodel >2 && nresult==0 ){
        !          11272:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11273:            goto end;
                   11274:          }
1.259   ! brouard  11275:          break;
1.258     brouard  11276:        default:
                   11277:          nresult=1;
                   11278:          decoderesult(".",nresult ); /* No covariate */
                   11279:        }
                   11280:       } /* End switch parameterline */
                   11281:     }while(endishere==0); /* End do */
1.126     brouard  11282:     
1.230     brouard  11283:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11284:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11285:     
                   11286:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11287:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11288:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11289: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11290: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11291:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11292: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11293: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11294:     }else{
1.218     brouard  11295:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11296:     }
                   11297:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11298:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11299:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11300:                
1.225     brouard  11301:     /*------------ free_vector  -------------*/
                   11302:     /*  chdir(path); */
1.220     brouard  11303:                
1.215     brouard  11304:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11305:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11306:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11307:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11308:     free_lvector(num,1,n);
                   11309:     free_vector(agedc,1,n);
                   11310:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11311:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11312:     fclose(ficparo);
                   11313:     fclose(ficres);
1.220     brouard  11314:                
                   11315:                
1.186     brouard  11316:     /* Other results (useful)*/
1.220     brouard  11317:                
                   11318:                
1.126     brouard  11319:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11320:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11321:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11322:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11323:     fclose(ficrespl);
                   11324: 
                   11325:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11326:     /*#include "hpijx.h"*/
                   11327:     hPijx(p, bage, fage);
1.145     brouard  11328:     fclose(ficrespij);
1.227     brouard  11329:     
1.220     brouard  11330:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11331:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11332:     k=1;
1.126     brouard  11333:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11334:     
1.219     brouard  11335:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11336:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11337:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11338:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11339:        for(k=1;k<=ncovcombmax;k++)
                   11340:          probs[i][j][k]=0.;
1.219     brouard  11341:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11342:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11343:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11344:       for(i=1;i<=AGESUP;i++)
                   11345:        for(j=1;j<=nlstate;j++)
                   11346:          for(k=1;k<=ncovcombmax;k++)
                   11347:            mobaverages[i][j][k]=0.;
1.219     brouard  11348:       mobaverage=mobaverages;
                   11349:       if (mobilav!=0) {
1.235     brouard  11350:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11351:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11352:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11353:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11354:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11355:        }
1.219     brouard  11356:       }
                   11357:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11358:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11359:       else if (mobilavproj !=0) {
1.235     brouard  11360:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11361:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11362:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11363:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11364:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11365:        }
1.219     brouard  11366:       }
                   11367:     }/* end if moving average */
1.227     brouard  11368:     
1.126     brouard  11369:     /*---------- Forecasting ------------------*/
                   11370:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11371:     if(prevfcast==1){
                   11372:       /*    if(stepm ==1){*/
1.225     brouard  11373:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11374:     }
1.217     brouard  11375:     if(backcast==1){
1.219     brouard  11376:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11377:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11378:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11379: 
                   11380:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11381: 
                   11382:       bprlim=matrix(1,nlstate,1,nlstate);
                   11383:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11384:       fclose(ficresplb);
                   11385: 
1.222     brouard  11386:       hBijx(p, bage, fage, mobaverage);
                   11387:       fclose(ficrespijb);
1.219     brouard  11388:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11389: 
                   11390:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11391:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11392:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11393:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11394:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11395:     }
1.217     brouard  11396:     
1.186     brouard  11397:  
                   11398:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11399: 
1.215     brouard  11400:     free_ivector(wav,1,imx);
                   11401:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11402:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11403:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11404:                
                   11405:                
1.127     brouard  11406:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11407:                
1.201     brouard  11408:     strcpy(filerese,"E_");
                   11409:     strcat(filerese,fileresu);
1.126     brouard  11410:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11411:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11412:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11413:     }
1.208     brouard  11414:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11415:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11416: 
                   11417:     pstamp(ficreseij);
1.219     brouard  11418:                
1.235     brouard  11419:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11420:     if (cptcovn < 1){i1=1;}
                   11421:     
                   11422:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11423:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11424:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11425:        continue;
1.219     brouard  11426:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11427:       printf("\n#****** ");
1.225     brouard  11428:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11429:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11430:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11431:       }
                   11432:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11433:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11434:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11435:       }
                   11436:       fprintf(ficreseij,"******\n");
1.235     brouard  11437:       printf("******\n");
1.219     brouard  11438:       
                   11439:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11440:       oldm=oldms;savm=savms;
1.235     brouard  11441:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11442:       
1.219     brouard  11443:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11444:     }
                   11445:     fclose(ficreseij);
1.208     brouard  11446:     printf("done evsij\n");fflush(stdout);
                   11447:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11448:                
1.227     brouard  11449:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11450:                
                   11451:                
1.201     brouard  11452:     strcpy(filerest,"T_");
                   11453:     strcat(filerest,fileresu);
1.127     brouard  11454:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11455:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11456:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11457:     }
1.208     brouard  11458:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11459:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11460:                
1.126     brouard  11461: 
1.201     brouard  11462:     strcpy(fileresstde,"STDE_");
                   11463:     strcat(fileresstde,fileresu);
1.126     brouard  11464:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11465:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11466:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11467:     }
1.227     brouard  11468:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11469:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11470: 
1.201     brouard  11471:     strcpy(filerescve,"CVE_");
                   11472:     strcat(filerescve,fileresu);
1.126     brouard  11473:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11474:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11475:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11476:     }
1.227     brouard  11477:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11478:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11479: 
1.201     brouard  11480:     strcpy(fileresv,"V_");
                   11481:     strcat(fileresv,fileresu);
1.126     brouard  11482:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11483:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11484:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11485:     }
1.227     brouard  11486:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11487:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11488: 
1.145     brouard  11489:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11490:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11491:           
1.235     brouard  11492:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11493:     if (cptcovn < 1){i1=1;}
                   11494:     
                   11495:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11496:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11497:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11498:        continue;
1.242     brouard  11499:       printf("\n#****** Result for:");
                   11500:       fprintf(ficrest,"\n#****** Result for:");
                   11501:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11502:       for(j=1;j<=cptcoveff;j++){ 
                   11503:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11504:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11505:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11506:       }
1.235     brouard  11507:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11508:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11509:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11510:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11511:       }        
1.208     brouard  11512:       fprintf(ficrest,"******\n");
1.227     brouard  11513:       fprintf(ficlog,"******\n");
                   11514:       printf("******\n");
1.208     brouard  11515:       
                   11516:       fprintf(ficresstdeij,"\n#****** ");
                   11517:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11518:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11519:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11520:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11521:       }
1.235     brouard  11522:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11523:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11524:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11525:       }        
1.208     brouard  11526:       fprintf(ficresstdeij,"******\n");
                   11527:       fprintf(ficrescveij,"******\n");
                   11528:       
                   11529:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11530:       /* pstamp(ficresvij); */
1.225     brouard  11531:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11532:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11533:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11534:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11535:       }        
1.208     brouard  11536:       fprintf(ficresvij,"******\n");
                   11537:       
                   11538:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11539:       oldm=oldms;savm=savms;
1.235     brouard  11540:       printf(" cvevsij ");
                   11541:       fprintf(ficlog, " cvevsij ");
                   11542:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11543:       printf(" end cvevsij \n ");
                   11544:       fprintf(ficlog, " end cvevsij \n ");
                   11545:       
                   11546:       /*
                   11547:        */
                   11548:       /* goto endfree; */
                   11549:       
                   11550:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11551:       pstamp(ficrest);
                   11552:       
                   11553:       
                   11554:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11555:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11556:        cptcod= 0; /* To be deleted */
                   11557:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11558:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11559:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11560:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11561:        if(vpopbased==1)
                   11562:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11563:        else
                   11564:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11565:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11566:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11567:        fprintf(ficrest,"\n");
                   11568:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11569:        epj=vector(1,nlstate+1);
                   11570:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11571:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11572:        for(age=bage; age <=fage ;age++){
1.235     brouard  11573:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11574:          if (vpopbased==1) {
                   11575:            if(mobilav ==0){
                   11576:              for(i=1; i<=nlstate;i++)
                   11577:                prlim[i][i]=probs[(int)age][i][k];
                   11578:            }else{ /* mobilav */ 
                   11579:              for(i=1; i<=nlstate;i++)
                   11580:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11581:            }
                   11582:          }
1.219     brouard  11583:          
1.227     brouard  11584:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11585:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11586:          /* printf(" age %4.0f ",age); */
                   11587:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11588:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11589:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11590:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11591:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11592:            }
                   11593:            epj[nlstate+1] +=epj[j];
                   11594:          }
                   11595:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11596:          
1.227     brouard  11597:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11598:            for(j=1;j <=nlstate;j++)
                   11599:              vepp += vareij[i][j][(int)age];
                   11600:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11601:          for(j=1;j <=nlstate;j++){
                   11602:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11603:          }
                   11604:          fprintf(ficrest,"\n");
                   11605:        }
1.208     brouard  11606:       } /* End vpopbased */
                   11607:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11608:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11609:       free_vector(epj,1,nlstate+1);
1.235     brouard  11610:       printf("done selection\n");fflush(stdout);
                   11611:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11612:       
1.145     brouard  11613:       /*}*/
1.235     brouard  11614:     } /* End k selection */
1.227     brouard  11615: 
                   11616:     printf("done State-specific expectancies\n");fflush(stdout);
                   11617:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11618: 
1.126     brouard  11619:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11620:     
1.201     brouard  11621:     strcpy(fileresvpl,"VPL_");
                   11622:     strcat(fileresvpl,fileresu);
1.126     brouard  11623:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11624:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11625:       exit(0);
                   11626:     }
1.208     brouard  11627:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11628:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11629:     
1.145     brouard  11630:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11631:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11632:     
1.235     brouard  11633:     i1=pow(2,cptcoveff);
                   11634:     if (cptcovn < 1){i1=1;}
                   11635: 
                   11636:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11637:     for(k=1; k<=i1;k++){
1.253     brouard  11638:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11639:        continue;
1.227     brouard  11640:       fprintf(ficresvpl,"\n#****** ");
                   11641:       printf("\n#****** ");
                   11642:       fprintf(ficlog,"\n#****** ");
                   11643:       for(j=1;j<=cptcoveff;j++) {
                   11644:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11645:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11646:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11647:       }
1.235     brouard  11648:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11649:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11650:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11651:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11652:       }        
1.227     brouard  11653:       fprintf(ficresvpl,"******\n");
                   11654:       printf("******\n");
                   11655:       fprintf(ficlog,"******\n");
                   11656:       
                   11657:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11658:       oldm=oldms;savm=savms;
1.235     brouard  11659:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11660:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11661:       /*}*/
1.126     brouard  11662:     }
1.227     brouard  11663:     
1.126     brouard  11664:     fclose(ficresvpl);
1.208     brouard  11665:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11666:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11667:     
                   11668:     free_vector(weight,1,n);
                   11669:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11670:     free_imatrix(s,1,maxwav+1,1,n);
                   11671:     free_matrix(anint,1,maxwav,1,n); 
                   11672:     free_matrix(mint,1,maxwav,1,n);
                   11673:     free_ivector(cod,1,n);
                   11674:     free_ivector(tab,1,NCOVMAX);
                   11675:     fclose(ficresstdeij);
                   11676:     fclose(ficrescveij);
                   11677:     fclose(ficresvij);
                   11678:     fclose(ficrest);
                   11679:     fclose(ficpar);
                   11680:     
                   11681:     
1.126     brouard  11682:     /*---------- End : free ----------------*/
1.219     brouard  11683:     if (mobilav!=0 ||mobilavproj !=0)
                   11684:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11685:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11686:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11687:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11688:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11689:   /* endfree:*/
                   11690:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11691:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11692:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11693:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11694:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11695:   free_matrix(coqvar,1,maxwav,1,n);
                   11696:   free_matrix(covar,0,NCOVMAX,1,n);
                   11697:   free_matrix(matcov,1,npar,1,npar);
                   11698:   free_matrix(hess,1,npar,1,npar);
                   11699:   /*free_vector(delti,1,npar);*/
                   11700:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11701:   free_matrix(agev,1,maxwav,1,imx);
                   11702:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11703:   
                   11704:   free_ivector(ncodemax,1,NCOVMAX);
                   11705:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11706:   free_ivector(Dummy,-1,NCOVMAX);
                   11707:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11708:   free_ivector(DummyV,1,NCOVMAX);
                   11709:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11710:   free_ivector(Typevar,-1,NCOVMAX);
                   11711:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11712:   free_ivector(TvarsQ,1,NCOVMAX);
                   11713:   free_ivector(TvarsQind,1,NCOVMAX);
                   11714:   free_ivector(TvarsD,1,NCOVMAX);
                   11715:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11716:   free_ivector(TvarFD,1,NCOVMAX);
                   11717:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11718:   free_ivector(TvarF,1,NCOVMAX);
                   11719:   free_ivector(TvarFind,1,NCOVMAX);
                   11720:   free_ivector(TvarV,1,NCOVMAX);
                   11721:   free_ivector(TvarVind,1,NCOVMAX);
                   11722:   free_ivector(TvarA,1,NCOVMAX);
                   11723:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11724:   free_ivector(TvarFQ,1,NCOVMAX);
                   11725:   free_ivector(TvarFQind,1,NCOVMAX);
                   11726:   free_ivector(TvarVD,1,NCOVMAX);
                   11727:   free_ivector(TvarVDind,1,NCOVMAX);
                   11728:   free_ivector(TvarVQ,1,NCOVMAX);
                   11729:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11730:   free_ivector(Tvarsel,1,NCOVMAX);
                   11731:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11732:   free_ivector(Tposprod,1,NCOVMAX);
                   11733:   free_ivector(Tprod,1,NCOVMAX);
                   11734:   free_ivector(Tvaraff,1,NCOVMAX);
                   11735:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11736:   free_ivector(Tage,1,NCOVMAX);
                   11737:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11738:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11739:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11740:   
                   11741:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11742:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11743:   fflush(fichtm);
                   11744:   fflush(ficgp);
                   11745:   
1.227     brouard  11746:   
1.126     brouard  11747:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11748:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11749:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11750:   }else{
                   11751:     printf("End of Imach\n");
                   11752:     fprintf(ficlog,"End of Imach\n");
                   11753:   }
                   11754:   printf("See log file on %s\n",filelog);
                   11755:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11756:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11757:   rend_time = time(NULL);  
                   11758:   end_time = *localtime(&rend_time);
                   11759:   /* tml = *localtime(&end_time.tm_sec); */
                   11760:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11761:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11762:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11763:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11764:   
1.157     brouard  11765:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11766:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11767:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11768:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11769: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11770:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11771:   fclose(fichtm);
                   11772:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11773:   fclose(fichtmcov);
                   11774:   fclose(ficgp);
                   11775:   fclose(ficlog);
                   11776:   /*------ End -----------*/
1.227     brouard  11777:   
                   11778:   
                   11779:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11780: #ifdef WIN32
1.227     brouard  11781:   if (_chdir(pathcd) != 0)
                   11782:     printf("Can't move to directory %s!\n",path);
                   11783:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11784: #else
1.227     brouard  11785:     if(chdir(pathcd) != 0)
                   11786:       printf("Can't move to directory %s!\n", path);
                   11787:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11788: #endif 
1.126     brouard  11789:     printf("Current directory %s!\n",pathcd);
                   11790:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11791:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11792: #ifdef _WIN32
1.126     brouard  11793:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11794: #endif
                   11795:   if(!stat(plotcmd,&info)){
1.158     brouard  11796:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11797:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11798:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11799:     }else
                   11800:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11801: #ifdef __unix
1.126     brouard  11802:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11803:     if(!stat(plotcmd,&info)){
1.158     brouard  11804:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11805:     }else
                   11806:       strcpy(pplotcmd,plotcmd);
                   11807: #endif
                   11808:   }else
                   11809:     strcpy(pplotcmd,plotcmd);
                   11810:   
                   11811:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11812:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11813:   
1.126     brouard  11814:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11815:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11816:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11817:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11818:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11819:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11820:   }
1.158     brouard  11821:   printf(" Successful, please wait...");
1.126     brouard  11822:   while (z[0] != 'q') {
                   11823:     /* chdir(path); */
1.154     brouard  11824:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11825:     scanf("%s",z);
                   11826: /*     if (z[0] == 'c') system("./imach"); */
                   11827:     if (z[0] == 'e') {
1.158     brouard  11828: #ifdef __APPLE__
1.152     brouard  11829:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11830: #elif __linux
                   11831:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11832: #else
1.152     brouard  11833:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11834: #endif
                   11835:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11836:       system(pplotcmd);
1.126     brouard  11837:     }
                   11838:     else if (z[0] == 'g') system(plotcmd);
                   11839:     else if (z[0] == 'q') exit(0);
                   11840:   }
1.227     brouard  11841: end:
1.126     brouard  11842:   while (z[0] != 'q') {
1.195     brouard  11843:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11844:     scanf("%s",z);
                   11845:   }
                   11846: }

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