Annotation of imach/src/imach.c, revision 1.262

1.262   ! brouard     1: /* $Id: imach.c,v 1.261 2017/04/05 10:14:09 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.262   ! brouard     4:   Revision 1.261  2017/04/05 10:14:09  brouard
        !             5:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
        !             6: 
1.261     brouard     7:   Revision 1.260  2017/04/04 17:46:59  brouard
                      8:   Summary: Gnuplot indexations fixed (humm)
                      9: 
1.260     brouard    10:   Revision 1.259  2017/04/04 13:01:16  brouard
                     11:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     12: 
1.259     brouard    13:   Revision 1.258  2017/04/03 10:17:47  brouard
                     14:   Summary: Version 0.99r12
                     15: 
                     16:   Some cleanings, conformed with updated documentation.
                     17: 
1.258     brouard    18:   Revision 1.257  2017/03/29 16:53:30  brouard
                     19:   Summary: Temp
                     20: 
1.257     brouard    21:   Revision 1.256  2017/03/27 05:50:23  brouard
                     22:   Summary: Temporary
                     23: 
1.256     brouard    24:   Revision 1.255  2017/03/08 16:02:28  brouard
                     25:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     26: 
1.255     brouard    27:   Revision 1.254  2017/03/08 07:13:00  brouard
                     28:   Summary: Fixing data parameter line
                     29: 
1.254     brouard    30:   Revision 1.253  2016/12/15 11:59:41  brouard
                     31:   Summary: 0.99 in progress
                     32: 
1.253     brouard    33:   Revision 1.252  2016/09/15 21:15:37  brouard
                     34:   *** empty log message ***
                     35: 
1.252     brouard    36:   Revision 1.251  2016/09/15 15:01:13  brouard
                     37:   Summary: not working
                     38: 
1.251     brouard    39:   Revision 1.250  2016/09/08 16:07:27  brouard
                     40:   Summary: continue
                     41: 
1.250     brouard    42:   Revision 1.249  2016/09/07 17:14:18  brouard
                     43:   Summary: Starting values from frequencies
                     44: 
1.249     brouard    45:   Revision 1.248  2016/09/07 14:10:18  brouard
                     46:   *** empty log message ***
                     47: 
1.248     brouard    48:   Revision 1.247  2016/09/02 11:11:21  brouard
                     49:   *** empty log message ***
                     50: 
1.247     brouard    51:   Revision 1.246  2016/09/02 08:49:22  brouard
                     52:   *** empty log message ***
                     53: 
1.246     brouard    54:   Revision 1.245  2016/09/02 07:25:01  brouard
                     55:   *** empty log message ***
                     56: 
1.245     brouard    57:   Revision 1.244  2016/09/02 07:17:34  brouard
                     58:   *** empty log message ***
                     59: 
1.244     brouard    60:   Revision 1.243  2016/09/02 06:45:35  brouard
                     61:   *** empty log message ***
                     62: 
1.243     brouard    63:   Revision 1.242  2016/08/30 15:01:20  brouard
                     64:   Summary: Fixing a lots
                     65: 
1.242     brouard    66:   Revision 1.241  2016/08/29 17:17:25  brouard
                     67:   Summary: gnuplot problem in Back projection to fix
                     68: 
1.241     brouard    69:   Revision 1.240  2016/08/29 07:53:18  brouard
                     70:   Summary: Better
                     71: 
1.240     brouard    72:   Revision 1.239  2016/08/26 15:51:03  brouard
                     73:   Summary: Improvement in Powell output in order to copy and paste
                     74: 
                     75:   Author:
                     76: 
1.239     brouard    77:   Revision 1.238  2016/08/26 14:23:35  brouard
                     78:   Summary: Starting tests of 0.99
                     79: 
1.238     brouard    80:   Revision 1.237  2016/08/26 09:20:19  brouard
                     81:   Summary: to valgrind
                     82: 
1.237     brouard    83:   Revision 1.236  2016/08/25 10:50:18  brouard
                     84:   *** empty log message ***
                     85: 
1.236     brouard    86:   Revision 1.235  2016/08/25 06:59:23  brouard
                     87:   *** empty log message ***
                     88: 
1.235     brouard    89:   Revision 1.234  2016/08/23 16:51:20  brouard
                     90:   *** empty log message ***
                     91: 
1.234     brouard    92:   Revision 1.233  2016/08/23 07:40:50  brouard
                     93:   Summary: not working
                     94: 
1.233     brouard    95:   Revision 1.232  2016/08/22 14:20:21  brouard
                     96:   Summary: not working
                     97: 
1.232     brouard    98:   Revision 1.231  2016/08/22 07:17:15  brouard
                     99:   Summary: not working
                    100: 
1.231     brouard   101:   Revision 1.230  2016/08/22 06:55:53  brouard
                    102:   Summary: Not working
                    103: 
1.230     brouard   104:   Revision 1.229  2016/07/23 09:45:53  brouard
                    105:   Summary: Completing for func too
                    106: 
1.229     brouard   107:   Revision 1.228  2016/07/22 17:45:30  brouard
                    108:   Summary: Fixing some arrays, still debugging
                    109: 
1.227     brouard   110:   Revision 1.226  2016/07/12 18:42:34  brouard
                    111:   Summary: temp
                    112: 
1.226     brouard   113:   Revision 1.225  2016/07/12 08:40:03  brouard
                    114:   Summary: saving but not running
                    115: 
1.225     brouard   116:   Revision 1.224  2016/07/01 13:16:01  brouard
                    117:   Summary: Fixes
                    118: 
1.224     brouard   119:   Revision 1.223  2016/02/19 09:23:35  brouard
                    120:   Summary: temporary
                    121: 
1.223     brouard   122:   Revision 1.222  2016/02/17 08:14:50  brouard
                    123:   Summary: Probably last 0.98 stable version 0.98r6
                    124: 
1.222     brouard   125:   Revision 1.221  2016/02/15 23:35:36  brouard
                    126:   Summary: minor bug
                    127: 
1.220     brouard   128:   Revision 1.219  2016/02/15 00:48:12  brouard
                    129:   *** empty log message ***
                    130: 
1.219     brouard   131:   Revision 1.218  2016/02/12 11:29:23  brouard
                    132:   Summary: 0.99 Back projections
                    133: 
1.218     brouard   134:   Revision 1.217  2015/12/23 17:18:31  brouard
                    135:   Summary: Experimental backcast
                    136: 
1.217     brouard   137:   Revision 1.216  2015/12/18 17:32:11  brouard
                    138:   Summary: 0.98r4 Warning and status=-2
                    139: 
                    140:   Version 0.98r4 is now:
                    141:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    142:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    143:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    144: 
1.216     brouard   145:   Revision 1.215  2015/12/16 08:52:24  brouard
                    146:   Summary: 0.98r4 working
                    147: 
1.215     brouard   148:   Revision 1.214  2015/12/16 06:57:54  brouard
                    149:   Summary: temporary not working
                    150: 
1.214     brouard   151:   Revision 1.213  2015/12/11 18:22:17  brouard
                    152:   Summary: 0.98r4
                    153: 
1.213     brouard   154:   Revision 1.212  2015/11/21 12:47:24  brouard
                    155:   Summary: minor typo
                    156: 
1.212     brouard   157:   Revision 1.211  2015/11/21 12:41:11  brouard
                    158:   Summary: 0.98r3 with some graph of projected cross-sectional
                    159: 
                    160:   Author: Nicolas Brouard
                    161: 
1.211     brouard   162:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   163:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   164:   Summary: Adding ftolpl parameter
                    165:   Author: N Brouard
                    166: 
                    167:   We had difficulties to get smoothed confidence intervals. It was due
                    168:   to the period prevalence which wasn't computed accurately. The inner
                    169:   parameter ftolpl is now an outer parameter of the .imach parameter
                    170:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    171:   computation are long.
                    172: 
1.209     brouard   173:   Revision 1.208  2015/11/17 14:31:57  brouard
                    174:   Summary: temporary
                    175: 
1.208     brouard   176:   Revision 1.207  2015/10/27 17:36:57  brouard
                    177:   *** empty log message ***
                    178: 
1.207     brouard   179:   Revision 1.206  2015/10/24 07:14:11  brouard
                    180:   *** empty log message ***
                    181: 
1.206     brouard   182:   Revision 1.205  2015/10/23 15:50:53  brouard
                    183:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    184: 
1.205     brouard   185:   Revision 1.204  2015/10/01 16:20:26  brouard
                    186:   Summary: Some new graphs of contribution to likelihood
                    187: 
1.204     brouard   188:   Revision 1.203  2015/09/30 17:45:14  brouard
                    189:   Summary: looking at better estimation of the hessian
                    190: 
                    191:   Also a better criteria for convergence to the period prevalence And
                    192:   therefore adding the number of years needed to converge. (The
                    193:   prevalence in any alive state shold sum to one
                    194: 
1.203     brouard   195:   Revision 1.202  2015/09/22 19:45:16  brouard
                    196:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    197: 
1.202     brouard   198:   Revision 1.201  2015/09/15 17:34:58  brouard
                    199:   Summary: 0.98r0
                    200: 
                    201:   - Some new graphs like suvival functions
                    202:   - Some bugs fixed like model=1+age+V2.
                    203: 
1.201     brouard   204:   Revision 1.200  2015/09/09 16:53:55  brouard
                    205:   Summary: Big bug thanks to Flavia
                    206: 
                    207:   Even model=1+age+V2. did not work anymore
                    208: 
1.200     brouard   209:   Revision 1.199  2015/09/07 14:09:23  brouard
                    210:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    211: 
1.199     brouard   212:   Revision 1.198  2015/09/03 07:14:39  brouard
                    213:   Summary: 0.98q5 Flavia
                    214: 
1.198     brouard   215:   Revision 1.197  2015/09/01 18:24:39  brouard
                    216:   *** empty log message ***
                    217: 
1.197     brouard   218:   Revision 1.196  2015/08/18 23:17:52  brouard
                    219:   Summary: 0.98q5
                    220: 
1.196     brouard   221:   Revision 1.195  2015/08/18 16:28:39  brouard
                    222:   Summary: Adding a hack for testing purpose
                    223: 
                    224:   After reading the title, ftol and model lines, if the comment line has
                    225:   a q, starting with #q, the answer at the end of the run is quit. It
                    226:   permits to run test files in batch with ctest. The former workaround was
                    227:   $ echo q | imach foo.imach
                    228: 
1.195     brouard   229:   Revision 1.194  2015/08/18 13:32:00  brouard
                    230:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    231: 
1.194     brouard   232:   Revision 1.193  2015/08/04 07:17:42  brouard
                    233:   Summary: 0.98q4
                    234: 
1.193     brouard   235:   Revision 1.192  2015/07/16 16:49:02  brouard
                    236:   Summary: Fixing some outputs
                    237: 
1.192     brouard   238:   Revision 1.191  2015/07/14 10:00:33  brouard
                    239:   Summary: Some fixes
                    240: 
1.191     brouard   241:   Revision 1.190  2015/05/05 08:51:13  brouard
                    242:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    243: 
                    244:   Fix 1+age+.
                    245: 
1.190     brouard   246:   Revision 1.189  2015/04/30 14:45:16  brouard
                    247:   Summary: 0.98q2
                    248: 
1.189     brouard   249:   Revision 1.188  2015/04/30 08:27:53  brouard
                    250:   *** empty log message ***
                    251: 
1.188     brouard   252:   Revision 1.187  2015/04/29 09:11:15  brouard
                    253:   *** empty log message ***
                    254: 
1.187     brouard   255:   Revision 1.186  2015/04/23 12:01:52  brouard
                    256:   Summary: V1*age is working now, version 0.98q1
                    257: 
                    258:   Some codes had been disabled in order to simplify and Vn*age was
                    259:   working in the optimization phase, ie, giving correct MLE parameters,
                    260:   but, as usual, outputs were not correct and program core dumped.
                    261: 
1.186     brouard   262:   Revision 1.185  2015/03/11 13:26:42  brouard
                    263:   Summary: Inclusion of compile and links command line for Intel Compiler
                    264: 
1.185     brouard   265:   Revision 1.184  2015/03/11 11:52:39  brouard
                    266:   Summary: Back from Windows 8. Intel Compiler
                    267: 
1.184     brouard   268:   Revision 1.183  2015/03/10 20:34:32  brouard
                    269:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    270: 
                    271:   We use directest instead of original Powell test; probably no
                    272:   incidence on the results, but better justifications;
                    273:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    274:   wrong results.
                    275: 
1.183     brouard   276:   Revision 1.182  2015/02/12 08:19:57  brouard
                    277:   Summary: Trying to keep directest which seems simpler and more general
                    278:   Author: Nicolas Brouard
                    279: 
1.182     brouard   280:   Revision 1.181  2015/02/11 23:22:24  brouard
                    281:   Summary: Comments on Powell added
                    282: 
                    283:   Author:
                    284: 
1.181     brouard   285:   Revision 1.180  2015/02/11 17:33:45  brouard
                    286:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    287: 
1.180     brouard   288:   Revision 1.179  2015/01/04 09:57:06  brouard
                    289:   Summary: back to OS/X
                    290: 
1.179     brouard   291:   Revision 1.178  2015/01/04 09:35:48  brouard
                    292:   *** empty log message ***
                    293: 
1.178     brouard   294:   Revision 1.177  2015/01/03 18:40:56  brouard
                    295:   Summary: Still testing ilc32 on OSX
                    296: 
1.177     brouard   297:   Revision 1.176  2015/01/03 16:45:04  brouard
                    298:   *** empty log message ***
                    299: 
1.176     brouard   300:   Revision 1.175  2015/01/03 16:33:42  brouard
                    301:   *** empty log message ***
                    302: 
1.175     brouard   303:   Revision 1.174  2015/01/03 16:15:49  brouard
                    304:   Summary: Still in cross-compilation
                    305: 
1.174     brouard   306:   Revision 1.173  2015/01/03 12:06:26  brouard
                    307:   Summary: trying to detect cross-compilation
                    308: 
1.173     brouard   309:   Revision 1.172  2014/12/27 12:07:47  brouard
                    310:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    311: 
1.172     brouard   312:   Revision 1.171  2014/12/23 13:26:59  brouard
                    313:   Summary: Back from Visual C
                    314: 
                    315:   Still problem with utsname.h on Windows
                    316: 
1.171     brouard   317:   Revision 1.170  2014/12/23 11:17:12  brouard
                    318:   Summary: Cleaning some \%% back to %%
                    319: 
                    320:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    321: 
1.170     brouard   322:   Revision 1.169  2014/12/22 23:08:31  brouard
                    323:   Summary: 0.98p
                    324: 
                    325:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    326: 
1.169     brouard   327:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   328:   Summary: update
1.169     brouard   329: 
1.168     brouard   330:   Revision 1.167  2014/12/22 13:50:56  brouard
                    331:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    332: 
                    333:   Testing on Linux 64
                    334: 
1.167     brouard   335:   Revision 1.166  2014/12/22 11:40:47  brouard
                    336:   *** empty log message ***
                    337: 
1.166     brouard   338:   Revision 1.165  2014/12/16 11:20:36  brouard
                    339:   Summary: After compiling on Visual C
                    340: 
                    341:   * imach.c (Module): Merging 1.61 to 1.162
                    342: 
1.165     brouard   343:   Revision 1.164  2014/12/16 10:52:11  brouard
                    344:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    345: 
                    346:   * imach.c (Module): Merging 1.61 to 1.162
                    347: 
1.164     brouard   348:   Revision 1.163  2014/12/16 10:30:11  brouard
                    349:   * imach.c (Module): Merging 1.61 to 1.162
                    350: 
1.163     brouard   351:   Revision 1.162  2014/09/25 11:43:39  brouard
                    352:   Summary: temporary backup 0.99!
                    353: 
1.162     brouard   354:   Revision 1.1  2014/09/16 11:06:58  brouard
                    355:   Summary: With some code (wrong) for nlopt
                    356: 
                    357:   Author:
                    358: 
                    359:   Revision 1.161  2014/09/15 20:41:41  brouard
                    360:   Summary: Problem with macro SQR on Intel compiler
                    361: 
1.161     brouard   362:   Revision 1.160  2014/09/02 09:24:05  brouard
                    363:   *** empty log message ***
                    364: 
1.160     brouard   365:   Revision 1.159  2014/09/01 10:34:10  brouard
                    366:   Summary: WIN32
                    367:   Author: Brouard
                    368: 
1.159     brouard   369:   Revision 1.158  2014/08/27 17:11:51  brouard
                    370:   *** empty log message ***
                    371: 
1.158     brouard   372:   Revision 1.157  2014/08/27 16:26:55  brouard
                    373:   Summary: Preparing windows Visual studio version
                    374:   Author: Brouard
                    375: 
                    376:   In order to compile on Visual studio, time.h is now correct and time_t
                    377:   and tm struct should be used. difftime should be used but sometimes I
                    378:   just make the differences in raw time format (time(&now).
                    379:   Trying to suppress #ifdef LINUX
                    380:   Add xdg-open for __linux in order to open default browser.
                    381: 
1.157     brouard   382:   Revision 1.156  2014/08/25 20:10:10  brouard
                    383:   *** empty log message ***
                    384: 
1.156     brouard   385:   Revision 1.155  2014/08/25 18:32:34  brouard
                    386:   Summary: New compile, minor changes
                    387:   Author: Brouard
                    388: 
1.155     brouard   389:   Revision 1.154  2014/06/20 17:32:08  brouard
                    390:   Summary: Outputs now all graphs of convergence to period prevalence
                    391: 
1.154     brouard   392:   Revision 1.153  2014/06/20 16:45:46  brouard
                    393:   Summary: If 3 live state, convergence to period prevalence on same graph
                    394:   Author: Brouard
                    395: 
1.153     brouard   396:   Revision 1.152  2014/06/18 17:54:09  brouard
                    397:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    398: 
1.152     brouard   399:   Revision 1.151  2014/06/18 16:43:30  brouard
                    400:   *** empty log message ***
                    401: 
1.151     brouard   402:   Revision 1.150  2014/06/18 16:42:35  brouard
                    403:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    404:   Author: brouard
                    405: 
1.150     brouard   406:   Revision 1.149  2014/06/18 15:51:14  brouard
                    407:   Summary: Some fixes in parameter files errors
                    408:   Author: Nicolas Brouard
                    409: 
1.149     brouard   410:   Revision 1.148  2014/06/17 17:38:48  brouard
                    411:   Summary: Nothing new
                    412:   Author: Brouard
                    413: 
                    414:   Just a new packaging for OS/X version 0.98nS
                    415: 
1.148     brouard   416:   Revision 1.147  2014/06/16 10:33:11  brouard
                    417:   *** empty log message ***
                    418: 
1.147     brouard   419:   Revision 1.146  2014/06/16 10:20:28  brouard
                    420:   Summary: Merge
                    421:   Author: Brouard
                    422: 
                    423:   Merge, before building revised version.
                    424: 
1.146     brouard   425:   Revision 1.145  2014/06/10 21:23:15  brouard
                    426:   Summary: Debugging with valgrind
                    427:   Author: Nicolas Brouard
                    428: 
                    429:   Lot of changes in order to output the results with some covariates
                    430:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    431:   improve the code.
                    432:   No more memory valgrind error but a lot has to be done in order to
                    433:   continue the work of splitting the code into subroutines.
                    434:   Also, decodemodel has been improved. Tricode is still not
                    435:   optimal. nbcode should be improved. Documentation has been added in
                    436:   the source code.
                    437: 
1.144     brouard   438:   Revision 1.143  2014/01/26 09:45:38  brouard
                    439:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    440: 
                    441:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    442:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    443: 
1.143     brouard   444:   Revision 1.142  2014/01/26 03:57:36  brouard
                    445:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    446: 
                    447:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    448: 
1.142     brouard   449:   Revision 1.141  2014/01/26 02:42:01  brouard
                    450:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    451: 
1.141     brouard   452:   Revision 1.140  2011/09/02 10:37:54  brouard
                    453:   Summary: times.h is ok with mingw32 now.
                    454: 
1.140     brouard   455:   Revision 1.139  2010/06/14 07:50:17  brouard
                    456:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    457:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    458: 
1.139     brouard   459:   Revision 1.138  2010/04/30 18:19:40  brouard
                    460:   *** empty log message ***
                    461: 
1.138     brouard   462:   Revision 1.137  2010/04/29 18:11:38  brouard
                    463:   (Module): Checking covariates for more complex models
                    464:   than V1+V2. A lot of change to be done. Unstable.
                    465: 
1.137     brouard   466:   Revision 1.136  2010/04/26 20:30:53  brouard
                    467:   (Module): merging some libgsl code. Fixing computation
                    468:   of likelione (using inter/intrapolation if mle = 0) in order to
                    469:   get same likelihood as if mle=1.
                    470:   Some cleaning of code and comments added.
                    471: 
1.136     brouard   472:   Revision 1.135  2009/10/29 15:33:14  brouard
                    473:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    474: 
1.135     brouard   475:   Revision 1.134  2009/10/29 13:18:53  brouard
                    476:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    477: 
1.134     brouard   478:   Revision 1.133  2009/07/06 10:21:25  brouard
                    479:   just nforces
                    480: 
1.133     brouard   481:   Revision 1.132  2009/07/06 08:22:05  brouard
                    482:   Many tings
                    483: 
1.132     brouard   484:   Revision 1.131  2009/06/20 16:22:47  brouard
                    485:   Some dimensions resccaled
                    486: 
1.131     brouard   487:   Revision 1.130  2009/05/26 06:44:34  brouard
                    488:   (Module): Max Covariate is now set to 20 instead of 8. A
                    489:   lot of cleaning with variables initialized to 0. Trying to make
                    490:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    491: 
1.130     brouard   492:   Revision 1.129  2007/08/31 13:49:27  lievre
                    493:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    494: 
1.129     lievre    495:   Revision 1.128  2006/06/30 13:02:05  brouard
                    496:   (Module): Clarifications on computing e.j
                    497: 
1.128     brouard   498:   Revision 1.127  2006/04/28 18:11:50  brouard
                    499:   (Module): Yes the sum of survivors was wrong since
                    500:   imach-114 because nhstepm was no more computed in the age
                    501:   loop. Now we define nhstepma in the age loop.
                    502:   (Module): In order to speed up (in case of numerous covariates) we
                    503:   compute health expectancies (without variances) in a first step
                    504:   and then all the health expectancies with variances or standard
                    505:   deviation (needs data from the Hessian matrices) which slows the
                    506:   computation.
                    507:   In the future we should be able to stop the program is only health
                    508:   expectancies and graph are needed without standard deviations.
                    509: 
1.127     brouard   510:   Revision 1.126  2006/04/28 17:23:28  brouard
                    511:   (Module): Yes the sum of survivors was wrong since
                    512:   imach-114 because nhstepm was no more computed in the age
                    513:   loop. Now we define nhstepma in the age loop.
                    514:   Version 0.98h
                    515: 
1.126     brouard   516:   Revision 1.125  2006/04/04 15:20:31  lievre
                    517:   Errors in calculation of health expectancies. Age was not initialized.
                    518:   Forecasting file added.
                    519: 
                    520:   Revision 1.124  2006/03/22 17:13:53  lievre
                    521:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    522:   The log-likelihood is printed in the log file
                    523: 
                    524:   Revision 1.123  2006/03/20 10:52:43  brouard
                    525:   * imach.c (Module): <title> changed, corresponds to .htm file
                    526:   name. <head> headers where missing.
                    527: 
                    528:   * imach.c (Module): Weights can have a decimal point as for
                    529:   English (a comma might work with a correct LC_NUMERIC environment,
                    530:   otherwise the weight is truncated).
                    531:   Modification of warning when the covariates values are not 0 or
                    532:   1.
                    533:   Version 0.98g
                    534: 
                    535:   Revision 1.122  2006/03/20 09:45:41  brouard
                    536:   (Module): Weights can have a decimal point as for
                    537:   English (a comma might work with a correct LC_NUMERIC environment,
                    538:   otherwise the weight is truncated).
                    539:   Modification of warning when the covariates values are not 0 or
                    540:   1.
                    541:   Version 0.98g
                    542: 
                    543:   Revision 1.121  2006/03/16 17:45:01  lievre
                    544:   * imach.c (Module): Comments concerning covariates added
                    545: 
                    546:   * imach.c (Module): refinements in the computation of lli if
                    547:   status=-2 in order to have more reliable computation if stepm is
                    548:   not 1 month. Version 0.98f
                    549: 
                    550:   Revision 1.120  2006/03/16 15:10:38  lievre
                    551:   (Module): refinements in the computation of lli if
                    552:   status=-2 in order to have more reliable computation if stepm is
                    553:   not 1 month. Version 0.98f
                    554: 
                    555:   Revision 1.119  2006/03/15 17:42:26  brouard
                    556:   (Module): Bug if status = -2, the loglikelihood was
                    557:   computed as likelihood omitting the logarithm. Version O.98e
                    558: 
                    559:   Revision 1.118  2006/03/14 18:20:07  brouard
                    560:   (Module): varevsij Comments added explaining the second
                    561:   table of variances if popbased=1 .
                    562:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    563:   (Module): Function pstamp added
                    564:   (Module): Version 0.98d
                    565: 
                    566:   Revision 1.117  2006/03/14 17:16:22  brouard
                    567:   (Module): varevsij Comments added explaining the second
                    568:   table of variances if popbased=1 .
                    569:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    570:   (Module): Function pstamp added
                    571:   (Module): Version 0.98d
                    572: 
                    573:   Revision 1.116  2006/03/06 10:29:27  brouard
                    574:   (Module): Variance-covariance wrong links and
                    575:   varian-covariance of ej. is needed (Saito).
                    576: 
                    577:   Revision 1.115  2006/02/27 12:17:45  brouard
                    578:   (Module): One freematrix added in mlikeli! 0.98c
                    579: 
                    580:   Revision 1.114  2006/02/26 12:57:58  brouard
                    581:   (Module): Some improvements in processing parameter
                    582:   filename with strsep.
                    583: 
                    584:   Revision 1.113  2006/02/24 14:20:24  brouard
                    585:   (Module): Memory leaks checks with valgrind and:
                    586:   datafile was not closed, some imatrix were not freed and on matrix
                    587:   allocation too.
                    588: 
                    589:   Revision 1.112  2006/01/30 09:55:26  brouard
                    590:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    591: 
                    592:   Revision 1.111  2006/01/25 20:38:18  brouard
                    593:   (Module): Lots of cleaning and bugs added (Gompertz)
                    594:   (Module): Comments can be added in data file. Missing date values
                    595:   can be a simple dot '.'.
                    596: 
                    597:   Revision 1.110  2006/01/25 00:51:50  brouard
                    598:   (Module): Lots of cleaning and bugs added (Gompertz)
                    599: 
                    600:   Revision 1.109  2006/01/24 19:37:15  brouard
                    601:   (Module): Comments (lines starting with a #) are allowed in data.
                    602: 
                    603:   Revision 1.108  2006/01/19 18:05:42  lievre
                    604:   Gnuplot problem appeared...
                    605:   To be fixed
                    606: 
                    607:   Revision 1.107  2006/01/19 16:20:37  brouard
                    608:   Test existence of gnuplot in imach path
                    609: 
                    610:   Revision 1.106  2006/01/19 13:24:36  brouard
                    611:   Some cleaning and links added in html output
                    612: 
                    613:   Revision 1.105  2006/01/05 20:23:19  lievre
                    614:   *** empty log message ***
                    615: 
                    616:   Revision 1.104  2005/09/30 16:11:43  lievre
                    617:   (Module): sump fixed, loop imx fixed, and simplifications.
                    618:   (Module): If the status is missing at the last wave but we know
                    619:   that the person is alive, then we can code his/her status as -2
                    620:   (instead of missing=-1 in earlier versions) and his/her
                    621:   contributions to the likelihood is 1 - Prob of dying from last
                    622:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    623:   the healthy state at last known wave). Version is 0.98
                    624: 
                    625:   Revision 1.103  2005/09/30 15:54:49  lievre
                    626:   (Module): sump fixed, loop imx fixed, and simplifications.
                    627: 
                    628:   Revision 1.102  2004/09/15 17:31:30  brouard
                    629:   Add the possibility to read data file including tab characters.
                    630: 
                    631:   Revision 1.101  2004/09/15 10:38:38  brouard
                    632:   Fix on curr_time
                    633: 
                    634:   Revision 1.100  2004/07/12 18:29:06  brouard
                    635:   Add version for Mac OS X. Just define UNIX in Makefile
                    636: 
                    637:   Revision 1.99  2004/06/05 08:57:40  brouard
                    638:   *** empty log message ***
                    639: 
                    640:   Revision 1.98  2004/05/16 15:05:56  brouard
                    641:   New version 0.97 . First attempt to estimate force of mortality
                    642:   directly from the data i.e. without the need of knowing the health
                    643:   state at each age, but using a Gompertz model: log u =a + b*age .
                    644:   This is the basic analysis of mortality and should be done before any
                    645:   other analysis, in order to test if the mortality estimated from the
                    646:   cross-longitudinal survey is different from the mortality estimated
                    647:   from other sources like vital statistic data.
                    648: 
                    649:   The same imach parameter file can be used but the option for mle should be -3.
                    650: 
1.133     brouard   651:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   652:   former routines in order to include the new code within the former code.
                    653: 
                    654:   The output is very simple: only an estimate of the intercept and of
                    655:   the slope with 95% confident intervals.
                    656: 
                    657:   Current limitations:
                    658:   A) Even if you enter covariates, i.e. with the
                    659:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    660:   B) There is no computation of Life Expectancy nor Life Table.
                    661: 
                    662:   Revision 1.97  2004/02/20 13:25:42  lievre
                    663:   Version 0.96d. Population forecasting command line is (temporarily)
                    664:   suppressed.
                    665: 
                    666:   Revision 1.96  2003/07/15 15:38:55  brouard
                    667:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    668:   rewritten within the same printf. Workaround: many printfs.
                    669: 
                    670:   Revision 1.95  2003/07/08 07:54:34  brouard
                    671:   * imach.c (Repository):
                    672:   (Repository): Using imachwizard code to output a more meaningful covariance
                    673:   matrix (cov(a12,c31) instead of numbers.
                    674: 
                    675:   Revision 1.94  2003/06/27 13:00:02  brouard
                    676:   Just cleaning
                    677: 
                    678:   Revision 1.93  2003/06/25 16:33:55  brouard
                    679:   (Module): On windows (cygwin) function asctime_r doesn't
                    680:   exist so I changed back to asctime which exists.
                    681:   (Module): Version 0.96b
                    682: 
                    683:   Revision 1.92  2003/06/25 16:30:45  brouard
                    684:   (Module): On windows (cygwin) function asctime_r doesn't
                    685:   exist so I changed back to asctime which exists.
                    686: 
                    687:   Revision 1.91  2003/06/25 15:30:29  brouard
                    688:   * imach.c (Repository): Duplicated warning errors corrected.
                    689:   (Repository): Elapsed time after each iteration is now output. It
                    690:   helps to forecast when convergence will be reached. Elapsed time
                    691:   is stamped in powell.  We created a new html file for the graphs
                    692:   concerning matrix of covariance. It has extension -cov.htm.
                    693: 
                    694:   Revision 1.90  2003/06/24 12:34:15  brouard
                    695:   (Module): Some bugs corrected for windows. Also, when
                    696:   mle=-1 a template is output in file "or"mypar.txt with the design
                    697:   of the covariance matrix to be input.
                    698: 
                    699:   Revision 1.89  2003/06/24 12:30:52  brouard
                    700:   (Module): Some bugs corrected for windows. Also, when
                    701:   mle=-1 a template is output in file "or"mypar.txt with the design
                    702:   of the covariance matrix to be input.
                    703: 
                    704:   Revision 1.88  2003/06/23 17:54:56  brouard
                    705:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    706: 
                    707:   Revision 1.87  2003/06/18 12:26:01  brouard
                    708:   Version 0.96
                    709: 
                    710:   Revision 1.86  2003/06/17 20:04:08  brouard
                    711:   (Module): Change position of html and gnuplot routines and added
                    712:   routine fileappend.
                    713: 
                    714:   Revision 1.85  2003/06/17 13:12:43  brouard
                    715:   * imach.c (Repository): Check when date of death was earlier that
                    716:   current date of interview. It may happen when the death was just
                    717:   prior to the death. In this case, dh was negative and likelihood
                    718:   was wrong (infinity). We still send an "Error" but patch by
                    719:   assuming that the date of death was just one stepm after the
                    720:   interview.
                    721:   (Repository): Because some people have very long ID (first column)
                    722:   we changed int to long in num[] and we added a new lvector for
                    723:   memory allocation. But we also truncated to 8 characters (left
                    724:   truncation)
                    725:   (Repository): No more line truncation errors.
                    726: 
                    727:   Revision 1.84  2003/06/13 21:44:43  brouard
                    728:   * imach.c (Repository): Replace "freqsummary" at a correct
                    729:   place. It differs from routine "prevalence" which may be called
                    730:   many times. Probs is memory consuming and must be used with
                    731:   parcimony.
                    732:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    733: 
                    734:   Revision 1.83  2003/06/10 13:39:11  lievre
                    735:   *** empty log message ***
                    736: 
                    737:   Revision 1.82  2003/06/05 15:57:20  brouard
                    738:   Add log in  imach.c and  fullversion number is now printed.
                    739: 
                    740: */
                    741: /*
                    742:    Interpolated Markov Chain
                    743: 
                    744:   Short summary of the programme:
                    745:   
1.227     brouard   746:   This program computes Healthy Life Expectancies or State-specific
                    747:   (if states aren't health statuses) Expectancies from
                    748:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    749: 
                    750:   -1- a first survey ("cross") where individuals from different ages
                    751:   are interviewed on their health status or degree of disability (in
                    752:   the case of a health survey which is our main interest)
                    753: 
                    754:   -2- at least a second wave of interviews ("longitudinal") which
                    755:   measure each change (if any) in individual health status.  Health
                    756:   expectancies are computed from the time spent in each health state
                    757:   according to a model. More health states you consider, more time is
                    758:   necessary to reach the Maximum Likelihood of the parameters involved
                    759:   in the model.  The simplest model is the multinomial logistic model
                    760:   where pij is the probability to be observed in state j at the second
                    761:   wave conditional to be observed in state i at the first
                    762:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    763:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    764:   have a more complex model than "constant and age", you should modify
                    765:   the program where the markup *Covariates have to be included here
                    766:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   767:   convergence.
                    768: 
                    769:   The advantage of this computer programme, compared to a simple
                    770:   multinomial logistic model, is clear when the delay between waves is not
                    771:   identical for each individual. Also, if a individual missed an
                    772:   intermediate interview, the information is lost, but taken into
                    773:   account using an interpolation or extrapolation.  
                    774: 
                    775:   hPijx is the probability to be observed in state i at age x+h
                    776:   conditional to the observed state i at age x. The delay 'h' can be
                    777:   split into an exact number (nh*stepm) of unobserved intermediate
                    778:   states. This elementary transition (by month, quarter,
                    779:   semester or year) is modelled as a multinomial logistic.  The hPx
                    780:   matrix is simply the matrix product of nh*stepm elementary matrices
                    781:   and the contribution of each individual to the likelihood is simply
                    782:   hPijx.
                    783: 
                    784:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   785:   of the life expectancies. It also computes the period (stable) prevalence.
                    786: 
                    787: Back prevalence and projections:
1.227     brouard   788: 
                    789:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    790:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    791:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    792:    mobilavproj)
                    793: 
                    794:     Computes the back prevalence limit for any combination of
                    795:     covariate values k at any age between ageminpar and agemaxpar and
                    796:     returns it in **bprlim. In the loops,
                    797: 
                    798:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    799:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    800: 
                    801:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   802:    Computes for any combination of covariates k and any age between bage and fage 
                    803:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    804:                        oldm=oldms;savm=savms;
1.227     brouard   805: 
                    806:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   807:      Computes the transition matrix starting at age 'age' over
                    808:      'nhstepm*hstepm*stepm' months (i.e. until
                    809:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   810:      nhstepm*hstepm matrices. 
                    811: 
                    812:      Returns p3mat[i][j][h] after calling
                    813:      p3mat[i][j][h]=matprod2(newm,
                    814:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    815:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    816:      oldm);
1.226     brouard   817: 
                    818: Important routines
                    819: 
                    820: - func (or funcone), computes logit (pij) distinguishing
                    821:   o fixed variables (single or product dummies or quantitative);
                    822:   o varying variables by:
                    823:    (1) wave (single, product dummies, quantitative), 
                    824:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    825:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    826:        % varying dummy (not done) or quantitative (not done);
                    827: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    828:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    829: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    830:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    831:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   832: 
1.226     brouard   833: 
                    834:   
1.133     brouard   835:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    836:            Institut national d'études démographiques, Paris.
1.126     brouard   837:   This software have been partly granted by Euro-REVES, a concerted action
                    838:   from the European Union.
                    839:   It is copyrighted identically to a GNU software product, ie programme and
                    840:   software can be distributed freely for non commercial use. Latest version
                    841:   can be accessed at http://euroreves.ined.fr/imach .
                    842: 
                    843:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    844:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    845:   
                    846:   **********************************************************************/
                    847: /*
                    848:   main
                    849:   read parameterfile
                    850:   read datafile
                    851:   concatwav
                    852:   freqsummary
                    853:   if (mle >= 1)
                    854:     mlikeli
                    855:   print results files
                    856:   if mle==1 
                    857:      computes hessian
                    858:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    859:       begin-prev-date,...
                    860:   open gnuplot file
                    861:   open html file
1.145     brouard   862:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    863:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    864:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    865:     freexexit2 possible for memory heap.
                    866: 
                    867:   h Pij x                         | pij_nom  ficrestpij
                    868:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    869:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    870:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    871: 
                    872:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    873:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    874:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    875:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    876:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    877: 
1.126     brouard   878:   forecasting if prevfcast==1 prevforecast call prevalence()
                    879:   health expectancies
                    880:   Variance-covariance of DFLE
                    881:   prevalence()
                    882:    movingaverage()
                    883:   varevsij() 
                    884:   if popbased==1 varevsij(,popbased)
                    885:   total life expectancies
                    886:   Variance of period (stable) prevalence
                    887:  end
                    888: */
                    889: 
1.187     brouard   890: /* #define DEBUG */
                    891: /* #define DEBUGBRENT */
1.203     brouard   892: /* #define DEBUGLINMIN */
                    893: /* #define DEBUGHESS */
                    894: #define DEBUGHESSIJ
1.224     brouard   895: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   896: #define POWELL /* Instead of NLOPT */
1.224     brouard   897: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   898: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    899: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   900: 
                    901: #include <math.h>
                    902: #include <stdio.h>
                    903: #include <stdlib.h>
                    904: #include <string.h>
1.226     brouard   905: #include <ctype.h>
1.159     brouard   906: 
                    907: #ifdef _WIN32
                    908: #include <io.h>
1.172     brouard   909: #include <windows.h>
                    910: #include <tchar.h>
1.159     brouard   911: #else
1.126     brouard   912: #include <unistd.h>
1.159     brouard   913: #endif
1.126     brouard   914: 
                    915: #include <limits.h>
                    916: #include <sys/types.h>
1.171     brouard   917: 
                    918: #if defined(__GNUC__)
                    919: #include <sys/utsname.h> /* Doesn't work on Windows */
                    920: #endif
                    921: 
1.126     brouard   922: #include <sys/stat.h>
                    923: #include <errno.h>
1.159     brouard   924: /* extern int errno; */
1.126     brouard   925: 
1.157     brouard   926: /* #ifdef LINUX */
                    927: /* #include <time.h> */
                    928: /* #include "timeval.h" */
                    929: /* #else */
                    930: /* #include <sys/time.h> */
                    931: /* #endif */
                    932: 
1.126     brouard   933: #include <time.h>
                    934: 
1.136     brouard   935: #ifdef GSL
                    936: #include <gsl/gsl_errno.h>
                    937: #include <gsl/gsl_multimin.h>
                    938: #endif
                    939: 
1.167     brouard   940: 
1.162     brouard   941: #ifdef NLOPT
                    942: #include <nlopt.h>
                    943: typedef struct {
                    944:   double (* function)(double [] );
                    945: } myfunc_data ;
                    946: #endif
                    947: 
1.126     brouard   948: /* #include <libintl.h> */
                    949: /* #define _(String) gettext (String) */
                    950: 
1.251     brouard   951: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   952: 
                    953: #define GNUPLOTPROGRAM "gnuplot"
                    954: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    955: #define FILENAMELENGTH 132
                    956: 
                    957: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    958: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    959: 
1.144     brouard   960: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    961: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   962: 
                    963: #define NINTERVMAX 8
1.144     brouard   964: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    965: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    966: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   967: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   968: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    969: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   970: #define MAXN 20000
1.144     brouard   971: #define YEARM 12. /**< Number of months per year */
1.218     brouard   972: /* #define AGESUP 130 */
                    973: #define AGESUP 150
                    974: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   975: #define AGEBASE 40
1.194     brouard   976: #define AGEOVERFLOW 1.e20
1.164     brouard   977: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   978: #ifdef _WIN32
                    979: #define DIRSEPARATOR '\\'
                    980: #define CHARSEPARATOR "\\"
                    981: #define ODIRSEPARATOR '/'
                    982: #else
1.126     brouard   983: #define DIRSEPARATOR '/'
                    984: #define CHARSEPARATOR "/"
                    985: #define ODIRSEPARATOR '\\'
                    986: #endif
                    987: 
1.262   ! brouard   988: /* $Id: imach.c,v 1.261 2017/04/05 10:14:09 brouard Exp $ */
1.126     brouard   989: /* $State: Exp $ */
1.196     brouard   990: #include "version.h"
                    991: char version[]=__IMACH_VERSION__;
1.224     brouard   992: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.262   ! brouard   993: char fullversion[]="$Revision: 1.261 $ $Date: 2017/04/05 10:14:09 $"; 
1.126     brouard   994: char strstart[80];
                    995: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   996: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   997: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   998: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    999: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1000: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1001: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1002: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1003: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1004: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1005: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1006: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1007: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1008: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1009: int nsd=0; /**< Total number of single dummy variables (output) */
                   1010: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1011: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1012: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1013: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1014: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1015: int cptcov=0; /* Working variable */
1.218     brouard  1016: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1017: int npar=NPARMAX;
                   1018: int nlstate=2; /* Number of live states */
                   1019: int ndeath=1; /* Number of dead states */
1.130     brouard  1020: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1021: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1022: int popbased=0;
                   1023: 
                   1024: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1025: int maxwav=0; /* Maxim number of waves */
                   1026: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1027: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1028: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1029:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1030: int mle=1, weightopt=0;
1.126     brouard  1031: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1032: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1033: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1034:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1035: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1036: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1037: 
1.130     brouard  1038: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1039: double **matprod2(); /* test */
1.126     brouard  1040: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1041: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1042: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1043: 
1.136     brouard  1044: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1045: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1046: FILE *ficlog, *ficrespow;
1.130     brouard  1047: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1048: double fretone; /* Only one call to likelihood */
1.130     brouard  1049: long ipmx=0; /* Number of contributions */
1.126     brouard  1050: double sw; /* Sum of weights */
                   1051: char filerespow[FILENAMELENGTH];
                   1052: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1053: FILE *ficresilk;
                   1054: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1055: FILE *ficresprobmorprev;
                   1056: FILE *fichtm, *fichtmcov; /* Html File */
                   1057: FILE *ficreseij;
                   1058: char filerese[FILENAMELENGTH];
                   1059: FILE *ficresstdeij;
                   1060: char fileresstde[FILENAMELENGTH];
                   1061: FILE *ficrescveij;
                   1062: char filerescve[FILENAMELENGTH];
                   1063: FILE  *ficresvij;
                   1064: char fileresv[FILENAMELENGTH];
                   1065: FILE  *ficresvpl;
                   1066: char fileresvpl[FILENAMELENGTH];
                   1067: char title[MAXLINE];
1.234     brouard  1068: char model[MAXLINE]; /**< The model line */
1.217     brouard  1069: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1070: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1071: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1072: char command[FILENAMELENGTH];
                   1073: int  outcmd=0;
                   1074: 
1.217     brouard  1075: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1076: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1077: char filelog[FILENAMELENGTH]; /* Log file */
                   1078: char filerest[FILENAMELENGTH];
                   1079: char fileregp[FILENAMELENGTH];
                   1080: char popfile[FILENAMELENGTH];
                   1081: 
                   1082: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1083: 
1.157     brouard  1084: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1085: /* struct timezone tzp; */
                   1086: /* extern int gettimeofday(); */
                   1087: struct tm tml, *gmtime(), *localtime();
                   1088: 
                   1089: extern time_t time();
                   1090: 
                   1091: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1092: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1093: struct tm tm;
                   1094: 
1.126     brouard  1095: char strcurr[80], strfor[80];
                   1096: 
                   1097: char *endptr;
                   1098: long lval;
                   1099: double dval;
                   1100: 
                   1101: #define NR_END 1
                   1102: #define FREE_ARG char*
                   1103: #define FTOL 1.0e-10
                   1104: 
                   1105: #define NRANSI 
1.240     brouard  1106: #define ITMAX 200
                   1107: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1108: 
                   1109: #define TOL 2.0e-4 
                   1110: 
                   1111: #define CGOLD 0.3819660 
                   1112: #define ZEPS 1.0e-10 
                   1113: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1114: 
                   1115: #define GOLD 1.618034 
                   1116: #define GLIMIT 100.0 
                   1117: #define TINY 1.0e-20 
                   1118: 
                   1119: static double maxarg1,maxarg2;
                   1120: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1121: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1122:   
                   1123: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1124: #define rint(a) floor(a+0.5)
1.166     brouard  1125: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1126: #define mytinydouble 1.0e-16
1.166     brouard  1127: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1128: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1129: /* static double dsqrarg; */
                   1130: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1131: static double sqrarg;
                   1132: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1133: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1134: int agegomp= AGEGOMP;
                   1135: 
                   1136: int imx; 
                   1137: int stepm=1;
                   1138: /* Stepm, step in month: minimum step interpolation*/
                   1139: 
                   1140: int estepm;
                   1141: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1142: 
                   1143: int m,nb;
                   1144: long *num;
1.197     brouard  1145: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1146: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1147:                   covariate for which somebody answered excluding 
                   1148:                   undefined. Usually 2: 0 and 1. */
                   1149: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1150:                             covariate for which somebody answered including 
                   1151:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1152: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1153: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1154: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1155: double *ageexmed,*agecens;
                   1156: double dateintmean=0;
                   1157: 
                   1158: double *weight;
                   1159: int **s; /* Status */
1.141     brouard  1160: double *agedc;
1.145     brouard  1161: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1162:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1163:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1164: double **coqvar; /* Fixed quantitative covariate iqv */
                   1165: double ***cotvar; /* Time varying covariate itv */
                   1166: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1167: double  idx; 
                   1168: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1169: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1170: /*k          1  2   3   4     5    6    7     8    9 */
                   1171: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1172: /* Tndvar[k]    1   2   3               4          5 */
                   1173: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1174: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1175: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1176: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1177: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1178: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1179: /* Tprod[i]=k           4               7            */
                   1180: /* Tage[i]=k                  5               8      */
                   1181: /* */
                   1182: /* Type                    */
                   1183: /* V         1  2  3  4  5 */
                   1184: /*           F  F  V  V  V */
                   1185: /*           D  Q  D  D  Q */
                   1186: /*                         */
                   1187: int *TvarsD;
                   1188: int *TvarsDind;
                   1189: int *TvarsQ;
                   1190: int *TvarsQind;
                   1191: 
1.235     brouard  1192: #define MAXRESULTLINES 10
                   1193: int nresult=0;
1.258     brouard  1194: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1195: int TKresult[MAXRESULTLINES];
1.237     brouard  1196: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1197: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1198: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1199: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1200: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1201: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1202: 
1.234     brouard  1203: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1204: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1205: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1206: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1207: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1208: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1209: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1210: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1211: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1212: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1213: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1214: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1215: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1216: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1217: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1218: 
1.230     brouard  1219: int *Tvarsel; /**< Selected covariates for output */
                   1220: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1221: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1222: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1223: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1224: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1225: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1226: int *Tage;
1.227     brouard  1227: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1228: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1229: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1230: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1231: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1232: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1233: int **Tvard;
                   1234: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1235: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1236: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1237:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1238:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1239: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1240: double *lsurv, *lpop, *tpop;
                   1241: 
1.231     brouard  1242: #define FD 1; /* Fixed dummy covariate */
                   1243: #define FQ 2; /* Fixed quantitative covariate */
                   1244: #define FP 3; /* Fixed product covariate */
                   1245: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1246: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1247: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1248: #define VD 10; /* Varying dummy covariate */
                   1249: #define VQ 11; /* Varying quantitative covariate */
                   1250: #define VP 12; /* Varying product covariate */
                   1251: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1252: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1253: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1254: #define APFD 16; /* Age product * fixed dummy covariate */
                   1255: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1256: #define APVD 18; /* Age product * varying dummy covariate */
                   1257: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1258: 
                   1259: #define FTYPE 1; /* Fixed covariate */
                   1260: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1261: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1262: 
                   1263: struct kmodel{
                   1264:        int maintype; /* main type */
                   1265:        int subtype; /* subtype */
                   1266: };
                   1267: struct kmodel modell[NCOVMAX];
                   1268: 
1.143     brouard  1269: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1270: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1271: 
                   1272: /**************** split *************************/
                   1273: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1274: {
                   1275:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1276:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1277:   */ 
                   1278:   char *ss;                            /* pointer */
1.186     brouard  1279:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1280: 
                   1281:   l1 = strlen(path );                  /* length of path */
                   1282:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1283:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1284:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1285:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1286:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1287:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1288:     /* get current working directory */
                   1289:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1290: #ifdef WIN32
                   1291:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1292: #else
                   1293:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1294: #endif
1.126     brouard  1295:       return( GLOCK_ERROR_GETCWD );
                   1296:     }
                   1297:     /* got dirc from getcwd*/
                   1298:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1299:   } else {                             /* strip directory from path */
1.126     brouard  1300:     ss++;                              /* after this, the filename */
                   1301:     l2 = strlen( ss );                 /* length of filename */
                   1302:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1303:     strcpy( name, ss );                /* save file name */
                   1304:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1305:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1306:     printf(" DIRC2 = %s \n",dirc);
                   1307:   }
                   1308:   /* We add a separator at the end of dirc if not exists */
                   1309:   l1 = strlen( dirc );                 /* length of directory */
                   1310:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1311:     dirc[l1] =  DIRSEPARATOR;
                   1312:     dirc[l1+1] = 0; 
                   1313:     printf(" DIRC3 = %s \n",dirc);
                   1314:   }
                   1315:   ss = strrchr( name, '.' );           /* find last / */
                   1316:   if (ss >0){
                   1317:     ss++;
                   1318:     strcpy(ext,ss);                    /* save extension */
                   1319:     l1= strlen( name);
                   1320:     l2= strlen(ss)+1;
                   1321:     strncpy( finame, name, l1-l2);
                   1322:     finame[l1-l2]= 0;
                   1323:   }
                   1324: 
                   1325:   return( 0 );                         /* we're done */
                   1326: }
                   1327: 
                   1328: 
                   1329: /******************************************/
                   1330: 
                   1331: void replace_back_to_slash(char *s, char*t)
                   1332: {
                   1333:   int i;
                   1334:   int lg=0;
                   1335:   i=0;
                   1336:   lg=strlen(t);
                   1337:   for(i=0; i<= lg; i++) {
                   1338:     (s[i] = t[i]);
                   1339:     if (t[i]== '\\') s[i]='/';
                   1340:   }
                   1341: }
                   1342: 
1.132     brouard  1343: char *trimbb(char *out, char *in)
1.137     brouard  1344: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1345:   char *s;
                   1346:   s=out;
                   1347:   while (*in != '\0'){
1.137     brouard  1348:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1349:       in++;
                   1350:     }
                   1351:     *out++ = *in++;
                   1352:   }
                   1353:   *out='\0';
                   1354:   return s;
                   1355: }
                   1356: 
1.187     brouard  1357: /* char *substrchaine(char *out, char *in, char *chain) */
                   1358: /* { */
                   1359: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1360: /*   char *s, *t; */
                   1361: /*   t=in;s=out; */
                   1362: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1363: /*     *out++ = *in++; */
                   1364: /*   } */
                   1365: 
                   1366: /*   /\* *in matches *chain *\/ */
                   1367: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1368: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1369: /*   } */
                   1370: /*   in--; chain--; */
                   1371: /*   while ( (*in != '\0')){ */
                   1372: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1373: /*     *out++ = *in++; */
                   1374: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1375: /*   } */
                   1376: /*   *out='\0'; */
                   1377: /*   out=s; */
                   1378: /*   return out; */
                   1379: /* } */
                   1380: char *substrchaine(char *out, char *in, char *chain)
                   1381: {
                   1382:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1383:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1384: 
                   1385:   char *strloc;
                   1386: 
                   1387:   strcpy (out, in); 
                   1388:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1389:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1390:   if(strloc != NULL){ 
                   1391:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1392:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1393:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1394:   }
                   1395:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1396:   return out;
                   1397: }
                   1398: 
                   1399: 
1.145     brouard  1400: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1401: {
1.187     brouard  1402:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1403:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1404:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1405:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1406:   */
1.160     brouard  1407:   char *s, *t;
1.145     brouard  1408:   t=in;s=in;
                   1409:   while ((*in != occ) && (*in != '\0')){
                   1410:     *alocc++ = *in++;
                   1411:   }
                   1412:   if( *in == occ){
                   1413:     *(alocc)='\0';
                   1414:     s=++in;
                   1415:   }
                   1416:  
                   1417:   if (s == t) {/* occ not found */
                   1418:     *(alocc-(in-s))='\0';
                   1419:     in=s;
                   1420:   }
                   1421:   while ( *in != '\0'){
                   1422:     *blocc++ = *in++;
                   1423:   }
                   1424: 
                   1425:   *blocc='\0';
                   1426:   return t;
                   1427: }
1.137     brouard  1428: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1429: {
1.187     brouard  1430:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1431:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1432:      gives blocc="abcdef2ghi" and alocc="j".
                   1433:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1434:   */
                   1435:   char *s, *t;
                   1436:   t=in;s=in;
                   1437:   while (*in != '\0'){
                   1438:     while( *in == occ){
                   1439:       *blocc++ = *in++;
                   1440:       s=in;
                   1441:     }
                   1442:     *blocc++ = *in++;
                   1443:   }
                   1444:   if (s == t) /* occ not found */
                   1445:     *(blocc-(in-s))='\0';
                   1446:   else
                   1447:     *(blocc-(in-s)-1)='\0';
                   1448:   in=s;
                   1449:   while ( *in != '\0'){
                   1450:     *alocc++ = *in++;
                   1451:   }
                   1452: 
                   1453:   *alocc='\0';
                   1454:   return s;
                   1455: }
                   1456: 
1.126     brouard  1457: int nbocc(char *s, char occ)
                   1458: {
                   1459:   int i,j=0;
                   1460:   int lg=20;
                   1461:   i=0;
                   1462:   lg=strlen(s);
                   1463:   for(i=0; i<= lg; i++) {
1.234     brouard  1464:     if  (s[i] == occ ) j++;
1.126     brouard  1465:   }
                   1466:   return j;
                   1467: }
                   1468: 
1.137     brouard  1469: /* void cutv(char *u,char *v, char*t, char occ) */
                   1470: /* { */
                   1471: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1472: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1473: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1474: /*   int i,lg,j,p=0; */
                   1475: /*   i=0; */
                   1476: /*   lg=strlen(t); */
                   1477: /*   for(j=0; j<=lg-1; j++) { */
                   1478: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1479: /*   } */
1.126     brouard  1480: 
1.137     brouard  1481: /*   for(j=0; j<p; j++) { */
                   1482: /*     (u[j] = t[j]); */
                   1483: /*   } */
                   1484: /*      u[p]='\0'; */
1.126     brouard  1485: 
1.137     brouard  1486: /*    for(j=0; j<= lg; j++) { */
                   1487: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1488: /*   } */
                   1489: /* } */
1.126     brouard  1490: 
1.160     brouard  1491: #ifdef _WIN32
                   1492: char * strsep(char **pp, const char *delim)
                   1493: {
                   1494:   char *p, *q;
                   1495:          
                   1496:   if ((p = *pp) == NULL)
                   1497:     return 0;
                   1498:   if ((q = strpbrk (p, delim)) != NULL)
                   1499:   {
                   1500:     *pp = q + 1;
                   1501:     *q = '\0';
                   1502:   }
                   1503:   else
                   1504:     *pp = 0;
                   1505:   return p;
                   1506: }
                   1507: #endif
                   1508: 
1.126     brouard  1509: /********************** nrerror ********************/
                   1510: 
                   1511: void nrerror(char error_text[])
                   1512: {
                   1513:   fprintf(stderr,"ERREUR ...\n");
                   1514:   fprintf(stderr,"%s\n",error_text);
                   1515:   exit(EXIT_FAILURE);
                   1516: }
                   1517: /*********************** vector *******************/
                   1518: double *vector(int nl, int nh)
                   1519: {
                   1520:   double *v;
                   1521:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1522:   if (!v) nrerror("allocation failure in vector");
                   1523:   return v-nl+NR_END;
                   1524: }
                   1525: 
                   1526: /************************ free vector ******************/
                   1527: void free_vector(double*v, int nl, int nh)
                   1528: {
                   1529:   free((FREE_ARG)(v+nl-NR_END));
                   1530: }
                   1531: 
                   1532: /************************ivector *******************************/
                   1533: int *ivector(long nl,long nh)
                   1534: {
                   1535:   int *v;
                   1536:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1537:   if (!v) nrerror("allocation failure in ivector");
                   1538:   return v-nl+NR_END;
                   1539: }
                   1540: 
                   1541: /******************free ivector **************************/
                   1542: void free_ivector(int *v, long nl, long nh)
                   1543: {
                   1544:   free((FREE_ARG)(v+nl-NR_END));
                   1545: }
                   1546: 
                   1547: /************************lvector *******************************/
                   1548: long *lvector(long nl,long nh)
                   1549: {
                   1550:   long *v;
                   1551:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1552:   if (!v) nrerror("allocation failure in ivector");
                   1553:   return v-nl+NR_END;
                   1554: }
                   1555: 
                   1556: /******************free lvector **************************/
                   1557: void free_lvector(long *v, long nl, long nh)
                   1558: {
                   1559:   free((FREE_ARG)(v+nl-NR_END));
                   1560: }
                   1561: 
                   1562: /******************* imatrix *******************************/
                   1563: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1564:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1565: { 
                   1566:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1567:   int **m; 
                   1568:   
                   1569:   /* allocate pointers to rows */ 
                   1570:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1571:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1572:   m += NR_END; 
                   1573:   m -= nrl; 
                   1574:   
                   1575:   
                   1576:   /* allocate rows and set pointers to them */ 
                   1577:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1578:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1579:   m[nrl] += NR_END; 
                   1580:   m[nrl] -= ncl; 
                   1581:   
                   1582:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1583:   
                   1584:   /* return pointer to array of pointers to rows */ 
                   1585:   return m; 
                   1586: } 
                   1587: 
                   1588: /****************** free_imatrix *************************/
                   1589: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1590:       int **m;
                   1591:       long nch,ncl,nrh,nrl; 
                   1592:      /* free an int matrix allocated by imatrix() */ 
                   1593: { 
                   1594:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1595:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1596: } 
                   1597: 
                   1598: /******************* matrix *******************************/
                   1599: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1600: {
                   1601:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1602:   double **m;
                   1603: 
                   1604:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1605:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1606:   m += NR_END;
                   1607:   m -= nrl;
                   1608: 
                   1609:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1610:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1611:   m[nrl] += NR_END;
                   1612:   m[nrl] -= ncl;
                   1613: 
                   1614:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1615:   return m;
1.145     brouard  1616:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1617: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1618: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1619:    */
                   1620: }
                   1621: 
                   1622: /*************************free matrix ************************/
                   1623: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1624: {
                   1625:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1626:   free((FREE_ARG)(m+nrl-NR_END));
                   1627: }
                   1628: 
                   1629: /******************* ma3x *******************************/
                   1630: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1631: {
                   1632:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1633:   double ***m;
                   1634: 
                   1635:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1636:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1637:   m += NR_END;
                   1638:   m -= nrl;
                   1639: 
                   1640:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1641:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1642:   m[nrl] += NR_END;
                   1643:   m[nrl] -= ncl;
                   1644: 
                   1645:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1646: 
                   1647:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1648:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1649:   m[nrl][ncl] += NR_END;
                   1650:   m[nrl][ncl] -= nll;
                   1651:   for (j=ncl+1; j<=nch; j++) 
                   1652:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1653:   
                   1654:   for (i=nrl+1; i<=nrh; i++) {
                   1655:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1656:     for (j=ncl+1; j<=nch; j++) 
                   1657:       m[i][j]=m[i][j-1]+nlay;
                   1658:   }
                   1659:   return m; 
                   1660:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1661:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1662:   */
                   1663: }
                   1664: 
                   1665: /*************************free ma3x ************************/
                   1666: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1667: {
                   1668:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1669:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1670:   free((FREE_ARG)(m+nrl-NR_END));
                   1671: }
                   1672: 
                   1673: /*************** function subdirf ***********/
                   1674: char *subdirf(char fileres[])
                   1675: {
                   1676:   /* Caution optionfilefiname is hidden */
                   1677:   strcpy(tmpout,optionfilefiname);
                   1678:   strcat(tmpout,"/"); /* Add to the right */
                   1679:   strcat(tmpout,fileres);
                   1680:   return tmpout;
                   1681: }
                   1682: 
                   1683: /*************** function subdirf2 ***********/
                   1684: char *subdirf2(char fileres[], char *preop)
                   1685: {
                   1686:   
                   1687:   /* Caution optionfilefiname is hidden */
                   1688:   strcpy(tmpout,optionfilefiname);
                   1689:   strcat(tmpout,"/");
                   1690:   strcat(tmpout,preop);
                   1691:   strcat(tmpout,fileres);
                   1692:   return tmpout;
                   1693: }
                   1694: 
                   1695: /*************** function subdirf3 ***********/
                   1696: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1697: {
                   1698:   
                   1699:   /* Caution optionfilefiname is hidden */
                   1700:   strcpy(tmpout,optionfilefiname);
                   1701:   strcat(tmpout,"/");
                   1702:   strcat(tmpout,preop);
                   1703:   strcat(tmpout,preop2);
                   1704:   strcat(tmpout,fileres);
                   1705:   return tmpout;
                   1706: }
1.213     brouard  1707:  
                   1708: /*************** function subdirfext ***********/
                   1709: char *subdirfext(char fileres[], char *preop, char *postop)
                   1710: {
                   1711:   
                   1712:   strcpy(tmpout,preop);
                   1713:   strcat(tmpout,fileres);
                   1714:   strcat(tmpout,postop);
                   1715:   return tmpout;
                   1716: }
1.126     brouard  1717: 
1.213     brouard  1718: /*************** function subdirfext3 ***********/
                   1719: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1720: {
                   1721:   
                   1722:   /* Caution optionfilefiname is hidden */
                   1723:   strcpy(tmpout,optionfilefiname);
                   1724:   strcat(tmpout,"/");
                   1725:   strcat(tmpout,preop);
                   1726:   strcat(tmpout,fileres);
                   1727:   strcat(tmpout,postop);
                   1728:   return tmpout;
                   1729: }
                   1730:  
1.162     brouard  1731: char *asc_diff_time(long time_sec, char ascdiff[])
                   1732: {
                   1733:   long sec_left, days, hours, minutes;
                   1734:   days = (time_sec) / (60*60*24);
                   1735:   sec_left = (time_sec) % (60*60*24);
                   1736:   hours = (sec_left) / (60*60) ;
                   1737:   sec_left = (sec_left) %(60*60);
                   1738:   minutes = (sec_left) /60;
                   1739:   sec_left = (sec_left) % (60);
                   1740:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1741:   return ascdiff;
                   1742: }
                   1743: 
1.126     brouard  1744: /***************** f1dim *************************/
                   1745: extern int ncom; 
                   1746: extern double *pcom,*xicom;
                   1747: extern double (*nrfunc)(double []); 
                   1748:  
                   1749: double f1dim(double x) 
                   1750: { 
                   1751:   int j; 
                   1752:   double f;
                   1753:   double *xt; 
                   1754:  
                   1755:   xt=vector(1,ncom); 
                   1756:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1757:   f=(*nrfunc)(xt); 
                   1758:   free_vector(xt,1,ncom); 
                   1759:   return f; 
                   1760: } 
                   1761: 
                   1762: /*****************brent *************************/
                   1763: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1764: {
                   1765:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1766:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1767:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1768:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1769:    * returned function value. 
                   1770:   */
1.126     brouard  1771:   int iter; 
                   1772:   double a,b,d,etemp;
1.159     brouard  1773:   double fu=0,fv,fw,fx;
1.164     brouard  1774:   double ftemp=0.;
1.126     brouard  1775:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1776:   double e=0.0; 
                   1777:  
                   1778:   a=(ax < cx ? ax : cx); 
                   1779:   b=(ax > cx ? ax : cx); 
                   1780:   x=w=v=bx; 
                   1781:   fw=fv=fx=(*f)(x); 
                   1782:   for (iter=1;iter<=ITMAX;iter++) { 
                   1783:     xm=0.5*(a+b); 
                   1784:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1785:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1786:     printf(".");fflush(stdout);
                   1787:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1788: #ifdef DEBUGBRENT
1.126     brouard  1789:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1790:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1791:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1792: #endif
                   1793:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1794:       *xmin=x; 
                   1795:       return fx; 
                   1796:     } 
                   1797:     ftemp=fu;
                   1798:     if (fabs(e) > tol1) { 
                   1799:       r=(x-w)*(fx-fv); 
                   1800:       q=(x-v)*(fx-fw); 
                   1801:       p=(x-v)*q-(x-w)*r; 
                   1802:       q=2.0*(q-r); 
                   1803:       if (q > 0.0) p = -p; 
                   1804:       q=fabs(q); 
                   1805:       etemp=e; 
                   1806:       e=d; 
                   1807:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1808:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1809:       else { 
1.224     brouard  1810:                                d=p/q; 
                   1811:                                u=x+d; 
                   1812:                                if (u-a < tol2 || b-u < tol2) 
                   1813:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1814:       } 
                   1815:     } else { 
                   1816:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1817:     } 
                   1818:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1819:     fu=(*f)(u); 
                   1820:     if (fu <= fx) { 
                   1821:       if (u >= x) a=x; else b=x; 
                   1822:       SHFT(v,w,x,u) 
1.183     brouard  1823:       SHFT(fv,fw,fx,fu) 
                   1824:     } else { 
                   1825:       if (u < x) a=u; else b=u; 
                   1826:       if (fu <= fw || w == x) { 
1.224     brouard  1827:                                v=w; 
                   1828:                                w=u; 
                   1829:                                fv=fw; 
                   1830:                                fw=fu; 
1.183     brouard  1831:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1832:                                v=u; 
                   1833:                                fv=fu; 
1.183     brouard  1834:       } 
                   1835:     } 
1.126     brouard  1836:   } 
                   1837:   nrerror("Too many iterations in brent"); 
                   1838:   *xmin=x; 
                   1839:   return fx; 
                   1840: } 
                   1841: 
                   1842: /****************** mnbrak ***********************/
                   1843: 
                   1844: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1845:            double (*func)(double)) 
1.183     brouard  1846: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1847: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1848: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1849: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1850:    */
1.126     brouard  1851:   double ulim,u,r,q, dum;
                   1852:   double fu; 
1.187     brouard  1853: 
                   1854:   double scale=10.;
                   1855:   int iterscale=0;
                   1856: 
                   1857:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1858:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1859: 
                   1860: 
                   1861:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1862:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1863:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1864:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1865:   /* } */
                   1866: 
1.126     brouard  1867:   if (*fb > *fa) { 
                   1868:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1869:     SHFT(dum,*fb,*fa,dum) 
                   1870:   } 
1.126     brouard  1871:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1872:   *fc=(*func)(*cx); 
1.183     brouard  1873: #ifdef DEBUG
1.224     brouard  1874:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1875:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1876: #endif
1.224     brouard  1877:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1878:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1879:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1880:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1881:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1882:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1883:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1884:       fu=(*func)(u); 
1.163     brouard  1885: #ifdef DEBUG
                   1886:       /* f(x)=A(x-u)**2+f(u) */
                   1887:       double A, fparabu; 
                   1888:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1889:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1890:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1891:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1892:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1893:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1894:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1895:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1896: #endif 
1.184     brouard  1897: #ifdef MNBRAKORIGINAL
1.183     brouard  1898: #else
1.191     brouard  1899: /*       if (fu > *fc) { */
                   1900: /* #ifdef DEBUG */
                   1901: /*       printf("mnbrak4  fu > fc \n"); */
                   1902: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1903: /* #endif */
                   1904: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1905: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1906: /*     dum=u; /\* Shifting c and u *\/ */
                   1907: /*     u = *cx; */
                   1908: /*     *cx = dum; */
                   1909: /*     dum = fu; */
                   1910: /*     fu = *fc; */
                   1911: /*     *fc =dum; */
                   1912: /*       } else { /\* end *\/ */
                   1913: /* #ifdef DEBUG */
                   1914: /*       printf("mnbrak3  fu < fc \n"); */
                   1915: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1916: /* #endif */
                   1917: /*     dum=u; /\* Shifting c and u *\/ */
                   1918: /*     u = *cx; */
                   1919: /*     *cx = dum; */
                   1920: /*     dum = fu; */
                   1921: /*     fu = *fc; */
                   1922: /*     *fc =dum; */
                   1923: /*       } */
1.224     brouard  1924: #ifdef DEBUGMNBRAK
                   1925:                 double A, fparabu; 
                   1926:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1927:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1928:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1929:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1930: #endif
1.191     brouard  1931:       dum=u; /* Shifting c and u */
                   1932:       u = *cx;
                   1933:       *cx = dum;
                   1934:       dum = fu;
                   1935:       fu = *fc;
                   1936:       *fc =dum;
1.183     brouard  1937: #endif
1.162     brouard  1938:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1939: #ifdef DEBUG
1.224     brouard  1940:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1941:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1942: #endif
1.126     brouard  1943:       fu=(*func)(u); 
                   1944:       if (fu < *fc) { 
1.183     brouard  1945: #ifdef DEBUG
1.224     brouard  1946:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1947:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1948: #endif
                   1949:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1950:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1951: #ifdef DEBUG
                   1952:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1953: #endif
                   1954:       } 
1.162     brouard  1955:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1956: #ifdef DEBUG
1.224     brouard  1957:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1958:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1959: #endif
1.126     brouard  1960:       u=ulim; 
                   1961:       fu=(*func)(u); 
1.183     brouard  1962:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1963: #ifdef DEBUG
1.224     brouard  1964:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1965:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1966: #endif
1.126     brouard  1967:       u=(*cx)+GOLD*(*cx-*bx); 
                   1968:       fu=(*func)(u); 
1.224     brouard  1969: #ifdef DEBUG
                   1970:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1971:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1972: #endif
1.183     brouard  1973:     } /* end tests */
1.126     brouard  1974:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1975:     SHFT(*fa,*fb,*fc,fu) 
                   1976: #ifdef DEBUG
1.224     brouard  1977:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1978:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1979: #endif
                   1980:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1981: } 
                   1982: 
                   1983: /*************** linmin ************************/
1.162     brouard  1984: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1985: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1986: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1987: the value of func at the returned location p . This is actually all accomplished by calling the
                   1988: routines mnbrak and brent .*/
1.126     brouard  1989: int ncom; 
                   1990: double *pcom,*xicom;
                   1991: double (*nrfunc)(double []); 
                   1992:  
1.224     brouard  1993: #ifdef LINMINORIGINAL
1.126     brouard  1994: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1995: #else
                   1996: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1997: #endif
1.126     brouard  1998: { 
                   1999:   double brent(double ax, double bx, double cx, 
                   2000:               double (*f)(double), double tol, double *xmin); 
                   2001:   double f1dim(double x); 
                   2002:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2003:              double *fc, double (*func)(double)); 
                   2004:   int j; 
                   2005:   double xx,xmin,bx,ax; 
                   2006:   double fx,fb,fa;
1.187     brouard  2007: 
1.203     brouard  2008: #ifdef LINMINORIGINAL
                   2009: #else
                   2010:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2011: #endif
                   2012:   
1.126     brouard  2013:   ncom=n; 
                   2014:   pcom=vector(1,n); 
                   2015:   xicom=vector(1,n); 
                   2016:   nrfunc=func; 
                   2017:   for (j=1;j<=n;j++) { 
                   2018:     pcom[j]=p[j]; 
1.202     brouard  2019:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2020:   } 
1.187     brouard  2021: 
1.203     brouard  2022: #ifdef LINMINORIGINAL
                   2023:   xx=1.;
                   2024: #else
                   2025:   axs=0.0;
                   2026:   xxs=1.;
                   2027:   do{
                   2028:     xx= xxs;
                   2029: #endif
1.187     brouard  2030:     ax=0.;
                   2031:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2032:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2033:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2034:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2035:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2036:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2037:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2038: #ifdef LINMINORIGINAL
                   2039: #else
                   2040:     if (fx != fx){
1.224     brouard  2041:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2042:                        printf("|");
                   2043:                        fprintf(ficlog,"|");
1.203     brouard  2044: #ifdef DEBUGLINMIN
1.224     brouard  2045:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2046: #endif
                   2047:     }
1.224     brouard  2048:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2049: #endif
                   2050:   
1.191     brouard  2051: #ifdef DEBUGLINMIN
                   2052:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2053:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2054: #endif
1.224     brouard  2055: #ifdef LINMINORIGINAL
                   2056: #else
                   2057:        if(fb == fx){ /* Flat function in the direction */
                   2058:                xmin=xx;
                   2059:     *flat=1;
                   2060:        }else{
                   2061:     *flat=0;
                   2062: #endif
                   2063:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2064:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2065:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2066:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2067:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2068:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2069: #ifdef DEBUG
1.224     brouard  2070:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2071:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2072: #endif
                   2073: #ifdef LINMINORIGINAL
                   2074: #else
                   2075:                        }
1.126     brouard  2076: #endif
1.191     brouard  2077: #ifdef DEBUGLINMIN
                   2078:   printf("linmin end ");
1.202     brouard  2079:   fprintf(ficlog,"linmin end ");
1.191     brouard  2080: #endif
1.126     brouard  2081:   for (j=1;j<=n;j++) { 
1.203     brouard  2082: #ifdef LINMINORIGINAL
                   2083:     xi[j] *= xmin; 
                   2084: #else
                   2085: #ifdef DEBUGLINMIN
                   2086:     if(xxs <1.0)
                   2087:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2088: #endif
                   2089:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2090: #ifdef DEBUGLINMIN
                   2091:     if(xxs <1.0)
                   2092:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2093: #endif
                   2094: #endif
1.187     brouard  2095:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2096:   } 
1.191     brouard  2097: #ifdef DEBUGLINMIN
1.203     brouard  2098:   printf("\n");
1.191     brouard  2099:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2100:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2101:   for (j=1;j<=n;j++) { 
1.202     brouard  2102:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2103:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2104:     if(j % ncovmodel == 0){
1.191     brouard  2105:       printf("\n");
1.202     brouard  2106:       fprintf(ficlog,"\n");
                   2107:     }
1.191     brouard  2108:   }
1.203     brouard  2109: #else
1.191     brouard  2110: #endif
1.126     brouard  2111:   free_vector(xicom,1,n); 
                   2112:   free_vector(pcom,1,n); 
                   2113: } 
                   2114: 
                   2115: 
                   2116: /*************** powell ************************/
1.162     brouard  2117: /*
                   2118: Minimization of a function func of n variables. Input consists of an initial starting point
                   2119: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2120: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2121: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2122: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2123: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2124:  */
1.224     brouard  2125: #ifdef LINMINORIGINAL
                   2126: #else
                   2127:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2128:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2129: #endif
1.126     brouard  2130: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2131:            double (*func)(double [])) 
                   2132: { 
1.224     brouard  2133: #ifdef LINMINORIGINAL
                   2134:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2135:              double (*func)(double [])); 
1.224     brouard  2136: #else 
1.241     brouard  2137:  void linmin(double p[], double xi[], int n, double *fret,
                   2138:             double (*func)(double []),int *flat); 
1.224     brouard  2139: #endif
1.239     brouard  2140:  int i,ibig,j,jk,k; 
1.126     brouard  2141:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2142:   double directest;
1.126     brouard  2143:   double fp,fptt;
                   2144:   double *xits;
                   2145:   int niterf, itmp;
1.224     brouard  2146: #ifdef LINMINORIGINAL
                   2147: #else
                   2148: 
                   2149:   flatdir=ivector(1,n); 
                   2150:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2151: #endif
1.126     brouard  2152: 
                   2153:   pt=vector(1,n); 
                   2154:   ptt=vector(1,n); 
                   2155:   xit=vector(1,n); 
                   2156:   xits=vector(1,n); 
                   2157:   *fret=(*func)(p); 
                   2158:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2159:   rcurr_time = time(NULL);  
1.126     brouard  2160:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2161:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2162:     ibig=0; 
                   2163:     del=0.0; 
1.157     brouard  2164:     rlast_time=rcurr_time;
                   2165:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2166:     rcurr_time = time(NULL);  
                   2167:     curr_time = *localtime(&rcurr_time);
                   2168:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2169:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2170: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2171:     for (i=1;i<=n;i++) {
1.126     brouard  2172:       fprintf(ficrespow," %.12lf", p[i]);
                   2173:     }
1.239     brouard  2174:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2175:     printf("\n#model=  1      +     age ");
                   2176:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2177:     if(nagesqr==1){
1.241     brouard  2178:        printf("  + age*age  ");
                   2179:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2180:     }
                   2181:     for(j=1;j <=ncovmodel-2;j++){
                   2182:       if(Typevar[j]==0) {
                   2183:        printf("  +      V%d  ",Tvar[j]);
                   2184:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2185:       }else if(Typevar[j]==1) {
                   2186:        printf("  +    V%d*age ",Tvar[j]);
                   2187:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2188:       }else if(Typevar[j]==2) {
                   2189:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2190:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2191:       }
                   2192:     }
1.126     brouard  2193:     printf("\n");
1.239     brouard  2194: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2195: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2196:     fprintf(ficlog,"\n");
1.239     brouard  2197:     for(i=1,jk=1; i <=nlstate; i++){
                   2198:       for(k=1; k <=(nlstate+ndeath); k++){
                   2199:        if (k != i) {
                   2200:          printf("%d%d ",i,k);
                   2201:          fprintf(ficlog,"%d%d ",i,k);
                   2202:          for(j=1; j <=ncovmodel; j++){
                   2203:            printf("%12.7f ",p[jk]);
                   2204:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2205:            jk++; 
                   2206:          }
                   2207:          printf("\n");
                   2208:          fprintf(ficlog,"\n");
                   2209:        }
                   2210:       }
                   2211:     }
1.241     brouard  2212:     if(*iter <=3 && *iter >1){
1.157     brouard  2213:       tml = *localtime(&rcurr_time);
                   2214:       strcpy(strcurr,asctime(&tml));
                   2215:       rforecast_time=rcurr_time; 
1.126     brouard  2216:       itmp = strlen(strcurr);
                   2217:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2218:        strcurr[itmp-1]='\0';
1.162     brouard  2219:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2220:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2221:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2222:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2223:        forecast_time = *localtime(&rforecast_time);
                   2224:        strcpy(strfor,asctime(&forecast_time));
                   2225:        itmp = strlen(strfor);
                   2226:        if(strfor[itmp-1]=='\n')
                   2227:          strfor[itmp-1]='\0';
                   2228:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2229:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2230:       }
                   2231:     }
1.187     brouard  2232:     for (i=1;i<=n;i++) { /* For each direction i */
                   2233:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2234:       fptt=(*fret); 
                   2235: #ifdef DEBUG
1.203     brouard  2236:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2237:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2238: #endif
1.203     brouard  2239:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2240:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2241: #ifdef LINMINORIGINAL
1.188     brouard  2242:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2243: #else
                   2244:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2245:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2246: #endif
                   2247:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2248:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2249:                                /* because that direction will be replaced unless the gain del is small */
                   2250:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2251:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2252:                                /* with the new direction. */
                   2253:                                del=fabs(fptt-(*fret)); 
                   2254:                                ibig=i; 
1.126     brouard  2255:       } 
                   2256: #ifdef DEBUG
                   2257:       printf("%d %.12e",i,(*fret));
                   2258:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2259:       for (j=1;j<=n;j++) {
1.224     brouard  2260:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2261:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2262:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2263:       }
                   2264:       for(j=1;j<=n;j++) {
1.225     brouard  2265:                                printf(" p(%d)=%.12e",j,p[j]);
                   2266:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2267:       }
                   2268:       printf("\n");
                   2269:       fprintf(ficlog,"\n");
                   2270: #endif
1.187     brouard  2271:     } /* end loop on each direction i */
                   2272:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2273:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2274:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2275:       for(j=1;j<=n;j++) {
1.225     brouard  2276:                                if(flatdir[j] >0){
                   2277:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2278:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2279:                                }
                   2280:                                /* printf("\n"); */
                   2281:                                /* fprintf(ficlog,"\n"); */
                   2282:                        }
1.243     brouard  2283:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2284:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2285:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2286:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2287:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2288:       /* decreased of more than 3.84  */
                   2289:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2290:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2291:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2292:                        
1.188     brouard  2293:       /* Starting the program with initial values given by a former maximization will simply change */
                   2294:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2295:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2296:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2297: #ifdef DEBUG
                   2298:       int k[2],l;
                   2299:       k[0]=1;
                   2300:       k[1]=-1;
                   2301:       printf("Max: %.12e",(*func)(p));
                   2302:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2303:       for (j=1;j<=n;j++) {
                   2304:        printf(" %.12e",p[j]);
                   2305:        fprintf(ficlog," %.12e",p[j]);
                   2306:       }
                   2307:       printf("\n");
                   2308:       fprintf(ficlog,"\n");
                   2309:       for(l=0;l<=1;l++) {
                   2310:        for (j=1;j<=n;j++) {
                   2311:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2312:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2313:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2314:        }
                   2315:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2316:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2317:       }
                   2318: #endif
                   2319: 
1.224     brouard  2320: #ifdef LINMINORIGINAL
                   2321: #else
                   2322:       free_ivector(flatdir,1,n); 
                   2323: #endif
1.126     brouard  2324:       free_vector(xit,1,n); 
                   2325:       free_vector(xits,1,n); 
                   2326:       free_vector(ptt,1,n); 
                   2327:       free_vector(pt,1,n); 
                   2328:       return; 
1.192     brouard  2329:     } /* enough precision */ 
1.240     brouard  2330:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2331:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2332:       ptt[j]=2.0*p[j]-pt[j]; 
                   2333:       xit[j]=p[j]-pt[j]; 
                   2334:       pt[j]=p[j]; 
                   2335:     } 
1.181     brouard  2336:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2337: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2338:                if (*iter <=4) {
1.225     brouard  2339: #else
                   2340: #endif
1.224     brouard  2341: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2342: #else
1.161     brouard  2343:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2344: #endif
1.162     brouard  2345:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2346:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2347:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2348:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2349:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2350:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2351:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2352:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2353:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2354:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2355:       /* mu² and del² are equal when f3=f1 */
                   2356:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2357:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2358:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2359:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2360: #ifdef NRCORIGINAL
                   2361:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2362: #else
                   2363:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2364:       t= t- del*SQR(fp-fptt);
1.183     brouard  2365: #endif
1.202     brouard  2366:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2367: #ifdef DEBUG
1.181     brouard  2368:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2369:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2370:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2371:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2372:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2373:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2374:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2375:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2376: #endif
1.183     brouard  2377: #ifdef POWELLORIGINAL
                   2378:       if (t < 0.0) { /* Then we use it for new direction */
                   2379: #else
1.182     brouard  2380:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2381:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2382:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2383:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2384:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2385:       } 
1.181     brouard  2386:       if (directest < 0.0) { /* Then we use it for new direction */
                   2387: #endif
1.191     brouard  2388: #ifdef DEBUGLINMIN
1.234     brouard  2389:        printf("Before linmin in direction P%d-P0\n",n);
                   2390:        for (j=1;j<=n;j++) {
                   2391:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2392:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2393:          if(j % ncovmodel == 0){
                   2394:            printf("\n");
                   2395:            fprintf(ficlog,"\n");
                   2396:          }
                   2397:        }
1.224     brouard  2398: #endif
                   2399: #ifdef LINMINORIGINAL
1.234     brouard  2400:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2401: #else
1.234     brouard  2402:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2403:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2404: #endif
1.234     brouard  2405:        
1.191     brouard  2406: #ifdef DEBUGLINMIN
1.234     brouard  2407:        for (j=1;j<=n;j++) { 
                   2408:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2409:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2410:          if(j % ncovmodel == 0){
                   2411:            printf("\n");
                   2412:            fprintf(ficlog,"\n");
                   2413:          }
                   2414:        }
1.224     brouard  2415: #endif
1.234     brouard  2416:        for (j=1;j<=n;j++) { 
                   2417:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2418:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2419:        }
1.224     brouard  2420: #ifdef LINMINORIGINAL
                   2421: #else
1.234     brouard  2422:        for (j=1, flatd=0;j<=n;j++) {
                   2423:          if(flatdir[j]>0)
                   2424:            flatd++;
                   2425:        }
                   2426:        if(flatd >0){
1.255     brouard  2427:          printf("%d flat directions: ",flatd);
                   2428:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2429:          for (j=1;j<=n;j++) { 
                   2430:            if(flatdir[j]>0){
                   2431:              printf("%d ",j);
                   2432:              fprintf(ficlog,"%d ",j);
                   2433:            }
                   2434:          }
                   2435:          printf("\n");
                   2436:          fprintf(ficlog,"\n");
                   2437:        }
1.191     brouard  2438: #endif
1.234     brouard  2439:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2440:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2441:        
1.126     brouard  2442: #ifdef DEBUG
1.234     brouard  2443:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2444:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2445:        for(j=1;j<=n;j++){
                   2446:          printf(" %lf",xit[j]);
                   2447:          fprintf(ficlog," %lf",xit[j]);
                   2448:        }
                   2449:        printf("\n");
                   2450:        fprintf(ficlog,"\n");
1.126     brouard  2451: #endif
1.192     brouard  2452:       } /* end of t or directest negative */
1.224     brouard  2453: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2454: #else
1.234     brouard  2455:       } /* end if (fptt < fp)  */
1.192     brouard  2456: #endif
1.225     brouard  2457: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2458:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2459: #else
1.224     brouard  2460: #endif
1.234     brouard  2461:                } /* loop iteration */ 
1.126     brouard  2462: } 
1.234     brouard  2463:   
1.126     brouard  2464: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2465:   
1.235     brouard  2466:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2467:   {
1.235     brouard  2468:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2469:        (and selected quantitative values in nres)
                   2470:        by left multiplying the unit
1.234     brouard  2471:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2472:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2473:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2474:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2475:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2476:   /* Initial matrix pimij */
                   2477:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2478:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2479:   /*  0,                   0                  , 1} */
                   2480:   /*
                   2481:    * and after some iteration: */
                   2482:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2483:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2484:   /*  0,                   0                  , 1} */
                   2485:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2486:   /* {0.51571254859325999, 0.4842874514067399, */
                   2487:   /*  0.51326036147820708, 0.48673963852179264} */
                   2488:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2489:     
1.126     brouard  2490:   int i, ii,j,k;
1.209     brouard  2491:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2492:   /* double **matprod2(); */ /* test */
1.218     brouard  2493:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2494:   double **newm;
1.209     brouard  2495:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2496:   int ncvloop=0;
1.169     brouard  2497:   
1.209     brouard  2498:   min=vector(1,nlstate);
                   2499:   max=vector(1,nlstate);
                   2500:   meandiff=vector(1,nlstate);
                   2501: 
1.218     brouard  2502:        /* Starting with matrix unity */
1.126     brouard  2503:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2504:     for (j=1;j<=nlstate+ndeath;j++){
                   2505:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2506:     }
1.169     brouard  2507:   
                   2508:   cov[1]=1.;
                   2509:   
                   2510:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2511:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2512:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2513:     ncvloop++;
1.126     brouard  2514:     newm=savm;
                   2515:     /* Covariates have to be included here again */
1.138     brouard  2516:     cov[2]=agefin;
1.187     brouard  2517:     if(nagesqr==1)
                   2518:       cov[3]= agefin*agefin;;
1.234     brouard  2519:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2520:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2521:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2522:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2523:     }
                   2524:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2525:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2526:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2527:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2528:     }
1.237     brouard  2529:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2530:       if(Dummy[Tvar[Tage[k]]]){
                   2531:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2532:       } else{
1.235     brouard  2533:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2534:       }
1.235     brouard  2535:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2536:     }
1.237     brouard  2537:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2538:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2539:       if(Dummy[Tvard[k][1]==0]){
                   2540:        if(Dummy[Tvard[k][2]==0]){
                   2541:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2542:        }else{
                   2543:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2544:        }
                   2545:       }else{
                   2546:        if(Dummy[Tvard[k][2]==0]){
                   2547:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2548:        }else{
                   2549:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2550:        }
                   2551:       }
1.234     brouard  2552:     }
1.138     brouard  2553:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2554:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2555:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2556:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2557:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2558:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2559:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2560:     
1.126     brouard  2561:     savm=oldm;
                   2562:     oldm=newm;
1.209     brouard  2563: 
                   2564:     for(j=1; j<=nlstate; j++){
                   2565:       max[j]=0.;
                   2566:       min[j]=1.;
                   2567:     }
                   2568:     for(i=1;i<=nlstate;i++){
                   2569:       sumnew=0;
                   2570:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2571:       for(j=1; j<=nlstate; j++){ 
                   2572:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2573:        max[j]=FMAX(max[j],prlim[i][j]);
                   2574:        min[j]=FMIN(min[j],prlim[i][j]);
                   2575:       }
                   2576:     }
                   2577: 
1.126     brouard  2578:     maxmax=0.;
1.209     brouard  2579:     for(j=1; j<=nlstate; j++){
                   2580:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2581:       maxmax=FMAX(maxmax,meandiff[j]);
                   2582:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2583:     } /* j loop */
1.203     brouard  2584:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2585:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2586:     if(maxmax < ftolpl){
1.209     brouard  2587:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2588:       free_vector(min,1,nlstate);
                   2589:       free_vector(max,1,nlstate);
                   2590:       free_vector(meandiff,1,nlstate);
1.126     brouard  2591:       return prlim;
                   2592:     }
1.169     brouard  2593:   } /* age loop */
1.208     brouard  2594:     /* After some age loop it doesn't converge */
1.209     brouard  2595:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2596: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2597:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2598:   free_vector(min,1,nlstate);
                   2599:   free_vector(max,1,nlstate);
                   2600:   free_vector(meandiff,1,nlstate);
1.208     brouard  2601:   
1.169     brouard  2602:   return prlim; /* should not reach here */
1.126     brouard  2603: }
                   2604: 
1.217     brouard  2605: 
                   2606:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2607: 
1.218     brouard  2608:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2609:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2610:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2611: {
1.218     brouard  2612:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2613:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2614:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2615:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2616:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2617:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2618:   /* Initial matrix pimij */
                   2619:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2620:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2621:   /*  0,                   0                  , 1} */
                   2622:   /*
                   2623:    * and after some iteration: */
                   2624:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2625:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2626:   /*  0,                   0                  , 1} */
                   2627:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2628:   /* {0.51571254859325999, 0.4842874514067399, */
                   2629:   /*  0.51326036147820708, 0.48673963852179264} */
                   2630:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2631: 
                   2632:   int i, ii,j,k;
1.247     brouard  2633:   int first=0;
1.217     brouard  2634:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2635:   /* double **matprod2(); */ /* test */
                   2636:   double **out, cov[NCOVMAX+1], **bmij();
                   2637:   double **newm;
1.218     brouard  2638:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2639:   double        **oldm, **savm;  /* for use */
                   2640: 
1.217     brouard  2641:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2642:   int ncvloop=0;
                   2643:   
                   2644:   min=vector(1,nlstate);
                   2645:   max=vector(1,nlstate);
                   2646:   meandiff=vector(1,nlstate);
                   2647: 
1.218     brouard  2648:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2649:        oldm=oldms; savm=savms;
                   2650: 
                   2651:        /* Starting with matrix unity */
                   2652:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2653:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2654:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2655:     }
                   2656:   
                   2657:   cov[1]=1.;
                   2658:   
                   2659:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2660:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2661:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2662:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2663:     ncvloop++;
1.218     brouard  2664:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2665:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2666:     /* Covariates have to be included here again */
                   2667:     cov[2]=agefin;
                   2668:     if(nagesqr==1)
                   2669:       cov[3]= agefin*agefin;;
1.242     brouard  2670:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2671:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2672:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2673:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2674:     }
                   2675:     /* for (k=1; k<=cptcovn;k++) { */
                   2676:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2677:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2678:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2679:     /* } */
                   2680:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2681:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2682:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2683:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2684:     }
                   2685:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2686:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2687:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2688:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2689:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2690:       if(Dummy[Tvar[Tage[k]]]){
                   2691:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2692:       } else{
                   2693:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2694:       }
                   2695:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2696:     }
                   2697:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2698:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2699:       if(Dummy[Tvard[k][1]==0]){
                   2700:        if(Dummy[Tvard[k][2]==0]){
                   2701:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2702:        }else{
                   2703:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2704:        }
                   2705:       }else{
                   2706:        if(Dummy[Tvard[k][2]==0]){
                   2707:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2708:        }else{
                   2709:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2710:        }
                   2711:       }
1.217     brouard  2712:     }
                   2713:     
                   2714:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2715:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2716:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2717:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2718:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2719:                /* ij should be linked to the correct index of cov */
                   2720:                /* age and covariate values ij are in 'cov', but we need to pass
                   2721:                 * ij for the observed prevalence at age and status and covariate
                   2722:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2723:                 */
                   2724:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2725:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2726:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2727:     savm=oldm;
                   2728:     oldm=newm;
                   2729:     for(j=1; j<=nlstate; j++){
                   2730:       max[j]=0.;
                   2731:       min[j]=1.;
                   2732:     }
                   2733:     for(j=1; j<=nlstate; j++){ 
                   2734:       for(i=1;i<=nlstate;i++){
1.234     brouard  2735:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2736:        bprlim[i][j]= newm[i][j];
                   2737:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2738:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2739:       }
                   2740:     }
1.218     brouard  2741:                
1.217     brouard  2742:     maxmax=0.;
                   2743:     for(i=1; i<=nlstate; i++){
                   2744:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2745:       maxmax=FMAX(maxmax,meandiff[i]);
                   2746:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2747:     } /* j loop */
                   2748:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2749:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2750:     if(maxmax < ftolpl){
1.220     brouard  2751:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2752:       free_vector(min,1,nlstate);
                   2753:       free_vector(max,1,nlstate);
                   2754:       free_vector(meandiff,1,nlstate);
                   2755:       return bprlim;
                   2756:     }
                   2757:   } /* age loop */
                   2758:     /* After some age loop it doesn't converge */
1.247     brouard  2759:   if(first){
                   2760:     first=1;
                   2761:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2762: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2763:   }
                   2764:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2765: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2766:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2767:   free_vector(min,1,nlstate);
                   2768:   free_vector(max,1,nlstate);
                   2769:   free_vector(meandiff,1,nlstate);
                   2770:   
                   2771:   return bprlim; /* should not reach here */
                   2772: }
                   2773: 
1.126     brouard  2774: /*************** transition probabilities ***************/ 
                   2775: 
                   2776: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2777: {
1.138     brouard  2778:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2779:      computes the probability to be observed in state j being in state i by appying the
                   2780:      model to the ncovmodel covariates (including constant and age).
                   2781:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2782:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2783:      ncth covariate in the global vector x is given by the formula:
                   2784:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2785:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2786:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2787:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2788:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2789:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2790:   */
                   2791:   double s1, lnpijopii;
1.126     brouard  2792:   /*double t34;*/
1.164     brouard  2793:   int i,j, nc, ii, jj;
1.126     brouard  2794: 
1.223     brouard  2795:   for(i=1; i<= nlstate; i++){
                   2796:     for(j=1; j<i;j++){
                   2797:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2798:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2799:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2800:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2801:       }
                   2802:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2803:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2804:     }
                   2805:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2806:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2807:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2808:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2809:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2810:       }
                   2811:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2812:     }
                   2813:   }
1.218     brouard  2814:   
1.223     brouard  2815:   for(i=1; i<= nlstate; i++){
                   2816:     s1=0;
                   2817:     for(j=1; j<i; j++){
                   2818:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2819:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2820:     }
                   2821:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2822:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2823:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2824:     }
                   2825:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2826:     ps[i][i]=1./(s1+1.);
                   2827:     /* Computing other pijs */
                   2828:     for(j=1; j<i; j++)
                   2829:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2830:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2831:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2832:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2833:   } /* end i */
1.218     brouard  2834:   
1.223     brouard  2835:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2836:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2837:       ps[ii][jj]=0;
                   2838:       ps[ii][ii]=1;
                   2839:     }
                   2840:   }
1.218     brouard  2841:   
                   2842:   
1.223     brouard  2843:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2844:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2845:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2846:   /*   } */
                   2847:   /*   printf("\n "); */
                   2848:   /* } */
                   2849:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2850:   /*
                   2851:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2852:                goto end;*/
1.223     brouard  2853:   return ps;
1.126     brouard  2854: }
                   2855: 
1.218     brouard  2856: /*************** backward transition probabilities ***************/ 
                   2857: 
                   2858:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2859: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2860:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2861: {
1.222     brouard  2862:   /* Computes the backward probability at age agefin and covariate ij
                   2863:    * and returns in **ps as well as **bmij.
                   2864:    */
1.218     brouard  2865:   int i, ii, j,k;
1.222     brouard  2866:   
                   2867:   double **out, **pmij();
                   2868:   double sumnew=0.;
1.218     brouard  2869:   double agefin;
1.222     brouard  2870:   
                   2871:   double **dnewm, **dsavm, **doldm;
                   2872:   double **bbmij;
                   2873:   
1.218     brouard  2874:   doldm=ddoldms; /* global pointers */
1.222     brouard  2875:   dnewm=ddnewms;
                   2876:   dsavm=ddsavms;
                   2877:   
                   2878:   agefin=cov[2];
                   2879:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2880:      the observed prevalence (with this covariate ij) */
                   2881:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2882:   /* We do have the matrix Px in savm  and we need pij */
                   2883:   for (j=1;j<=nlstate+ndeath;j++){
                   2884:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2885:     for (ii=1;ii<=nlstate;ii++){
                   2886:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2887:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2888:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2889:       if(sumnew >= 1.e-10){
                   2890:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2891:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2892:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2893:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2894:        /* }else */
                   2895:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2896:       }else{
1.242     brouard  2897:        ;
                   2898:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2899:       }
                   2900:     } /*End ii */
                   2901:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2902:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2903:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2904:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2905:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2906:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2907:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2908:   for (j=1;j<=nlstate+ndeath;j++){
                   2909:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2910:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2911:     }
                   2912:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2913:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2914:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2915:   /* end bmij */
                   2916:   return ps; 
1.218     brouard  2917: }
1.217     brouard  2918: /*************** transition probabilities ***************/ 
                   2919: 
1.218     brouard  2920: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2921: {
                   2922:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2923:      computes the probability to be observed in state j being in state i by appying the
                   2924:      model to the ncovmodel covariates (including constant and age).
                   2925:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2926:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2927:      ncth covariate in the global vector x is given by the formula:
                   2928:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2929:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2930:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2931:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2932:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2933:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2934:   */
                   2935:   double s1, lnpijopii;
                   2936:   /*double t34;*/
                   2937:   int i,j, nc, ii, jj;
                   2938: 
1.234     brouard  2939:   for(i=1; i<= nlstate; i++){
                   2940:     for(j=1; j<i;j++){
                   2941:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2942:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2943:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2944:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2945:       }
                   2946:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2947:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2948:     }
                   2949:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2950:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2951:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2952:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2953:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2954:       }
                   2955:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2956:     }
                   2957:   }
                   2958:   
                   2959:   for(i=1; i<= nlstate; i++){
                   2960:     s1=0;
                   2961:     for(j=1; j<i; j++){
                   2962:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2963:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2964:     }
                   2965:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2966:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2967:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2968:     }
                   2969:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2970:     ps[i][i]=1./(s1+1.);
                   2971:     /* Computing other pijs */
                   2972:     for(j=1; j<i; j++)
                   2973:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2974:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2975:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2976:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2977:   } /* end i */
                   2978:   
                   2979:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2980:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2981:       ps[ii][jj]=0;
                   2982:       ps[ii][ii]=1;
                   2983:     }
                   2984:   }
                   2985:   /* Added for backcast */ /* Transposed matrix too */
                   2986:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2987:     s1=0.;
                   2988:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2989:       s1+=ps[ii][jj];
                   2990:     }
                   2991:     for(ii=1; ii<= nlstate; ii++){
                   2992:       ps[ii][jj]=ps[ii][jj]/s1;
                   2993:     }
                   2994:   }
                   2995:   /* Transposition */
                   2996:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2997:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2998:       s1=ps[ii][jj];
                   2999:       ps[ii][jj]=ps[jj][ii];
                   3000:       ps[jj][ii]=s1;
                   3001:     }
                   3002:   }
                   3003:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3004:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3005:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3006:   /*   } */
                   3007:   /*   printf("\n "); */
                   3008:   /* } */
                   3009:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3010:   /*
                   3011:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3012:     goto end;*/
                   3013:   return ps;
1.217     brouard  3014: }
                   3015: 
                   3016: 
1.126     brouard  3017: /**************** Product of 2 matrices ******************/
                   3018: 
1.145     brouard  3019: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3020: {
                   3021:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3022:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3023:   /* in, b, out are matrice of pointers which should have been initialized 
                   3024:      before: only the contents of out is modified. The function returns
                   3025:      a pointer to pointers identical to out */
1.145     brouard  3026:   int i, j, k;
1.126     brouard  3027:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3028:     for(k=ncolol; k<=ncoloh; k++){
                   3029:       out[i][k]=0.;
                   3030:       for(j=ncl; j<=nch; j++)
                   3031:        out[i][k] +=in[i][j]*b[j][k];
                   3032:     }
1.126     brouard  3033:   return out;
                   3034: }
                   3035: 
                   3036: 
                   3037: /************* Higher Matrix Product ***************/
                   3038: 
1.235     brouard  3039: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3040: {
1.218     brouard  3041:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3042:      'nhstepm*hstepm*stepm' months (i.e. until
                   3043:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3044:      nhstepm*hstepm matrices. 
                   3045:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3046:      (typically every 2 years instead of every month which is too big 
                   3047:      for the memory).
                   3048:      Model is determined by parameters x and covariates have to be 
                   3049:      included manually here. 
                   3050: 
                   3051:      */
                   3052: 
                   3053:   int i, j, d, h, k;
1.131     brouard  3054:   double **out, cov[NCOVMAX+1];
1.126     brouard  3055:   double **newm;
1.187     brouard  3056:   double agexact;
1.214     brouard  3057:   double agebegin, ageend;
1.126     brouard  3058: 
                   3059:   /* Hstepm could be zero and should return the unit matrix */
                   3060:   for (i=1;i<=nlstate+ndeath;i++)
                   3061:     for (j=1;j<=nlstate+ndeath;j++){
                   3062:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3063:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3064:     }
                   3065:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3066:   for(h=1; h <=nhstepm; h++){
                   3067:     for(d=1; d <=hstepm; d++){
                   3068:       newm=savm;
                   3069:       /* Covariates have to be included here again */
                   3070:       cov[1]=1.;
1.214     brouard  3071:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3072:       cov[2]=agexact;
                   3073:       if(nagesqr==1)
1.227     brouard  3074:        cov[3]= agexact*agexact;
1.235     brouard  3075:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3076:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3077:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3078:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3079:       }
                   3080:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3081:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3082:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3083:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3084:       }
                   3085:       for (k=1; k<=cptcovage;k++){
                   3086:        if(Dummy[Tvar[Tage[k]]]){
                   3087:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3088:        } else{
                   3089:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3090:        }
                   3091:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3092:       }
                   3093:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3094:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3095:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3096:       }
                   3097:       /* for (k=1; k<=cptcovn;k++)  */
                   3098:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3099:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3100:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3101:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3102:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3103:       
                   3104:       
1.126     brouard  3105:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3106:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3107:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3108:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3109:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3110:       /* if((int)age == 70){ */
                   3111:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3112:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3113:       /*         printf("%d pmmij ",i); */
                   3114:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3115:       /*           printf("%f ",pmmij[i][j]); */
                   3116:       /*         } */
                   3117:       /*         printf(" oldm "); */
                   3118:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3119:       /*           printf("%f ",oldm[i][j]); */
                   3120:       /*         } */
                   3121:       /*         printf("\n"); */
                   3122:       /*       } */
                   3123:       /* } */
1.126     brouard  3124:       savm=oldm;
                   3125:       oldm=newm;
                   3126:     }
                   3127:     for(i=1; i<=nlstate+ndeath; i++)
                   3128:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3129:                                po[i][j][h]=newm[i][j];
                   3130:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3131:       }
1.128     brouard  3132:     /*printf("h=%d ",h);*/
1.126     brouard  3133:   } /* end h */
1.218     brouard  3134:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3135:   return po;
                   3136: }
                   3137: 
1.217     brouard  3138: /************* Higher Back Matrix Product ***************/
1.218     brouard  3139: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3140: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3141: {
1.218     brouard  3142:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3143:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3144:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3145:      nhstepm*hstepm matrices.
                   3146:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3147:      (typically every 2 years instead of every month which is too big
1.217     brouard  3148:      for the memory).
1.218     brouard  3149:      Model is determined by parameters x and covariates have to be
                   3150:      included manually here.
1.217     brouard  3151: 
1.222     brouard  3152:   */
1.217     brouard  3153: 
                   3154:   int i, j, d, h, k;
                   3155:   double **out, cov[NCOVMAX+1];
                   3156:   double **newm;
                   3157:   double agexact;
                   3158:   double agebegin, ageend;
1.222     brouard  3159:   double **oldm, **savm;
1.217     brouard  3160: 
1.222     brouard  3161:   oldm=oldms;savm=savms;
1.217     brouard  3162:   /* Hstepm could be zero and should return the unit matrix */
                   3163:   for (i=1;i<=nlstate+ndeath;i++)
                   3164:     for (j=1;j<=nlstate+ndeath;j++){
                   3165:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3166:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3167:     }
                   3168:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3169:   for(h=1; h <=nhstepm; h++){
                   3170:     for(d=1; d <=hstepm; d++){
                   3171:       newm=savm;
                   3172:       /* Covariates have to be included here again */
                   3173:       cov[1]=1.;
                   3174:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3175:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3176:       cov[2]=agexact;
                   3177:       if(nagesqr==1)
1.222     brouard  3178:        cov[3]= agexact*agexact;
1.218     brouard  3179:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3180:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3181:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3182:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3183:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3184:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3185:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3186:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3187:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3188:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3189:                        
                   3190:                        
1.217     brouard  3191:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3192:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3193:       /* Careful transposed matrix */
1.222     brouard  3194:       /* age is in cov[2] */
1.218     brouard  3195:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3196:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3197:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3198:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3199:       /* if((int)age == 70){ */
                   3200:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3201:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3202:       /*         printf("%d pmmij ",i); */
                   3203:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3204:       /*           printf("%f ",pmmij[i][j]); */
                   3205:       /*         } */
                   3206:       /*         printf(" oldm "); */
                   3207:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3208:       /*           printf("%f ",oldm[i][j]); */
                   3209:       /*         } */
                   3210:       /*         printf("\n"); */
                   3211:       /*       } */
                   3212:       /* } */
                   3213:       savm=oldm;
                   3214:       oldm=newm;
                   3215:     }
                   3216:     for(i=1; i<=nlstate+ndeath; i++)
                   3217:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3218:        po[i][j][h]=newm[i][j];
                   3219:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3220:       }
                   3221:     /*printf("h=%d ",h);*/
                   3222:   } /* end h */
1.222     brouard  3223:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3224:   return po;
                   3225: }
                   3226: 
                   3227: 
1.162     brouard  3228: #ifdef NLOPT
                   3229:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3230:   double fret;
                   3231:   double *xt;
                   3232:   int j;
                   3233:   myfunc_data *d2 = (myfunc_data *) pd;
                   3234: /* xt = (p1-1); */
                   3235:   xt=vector(1,n); 
                   3236:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3237: 
                   3238:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3239:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3240:   printf("Function = %.12lf ",fret);
                   3241:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3242:   printf("\n");
                   3243:  free_vector(xt,1,n);
                   3244:   return fret;
                   3245: }
                   3246: #endif
1.126     brouard  3247: 
                   3248: /*************** log-likelihood *************/
                   3249: double func( double *x)
                   3250: {
1.226     brouard  3251:   int i, ii, j, k, mi, d, kk;
                   3252:   int ioffset=0;
                   3253:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3254:   double **out;
                   3255:   double lli; /* Individual log likelihood */
                   3256:   int s1, s2;
1.228     brouard  3257:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3258:   double bbh, survp;
                   3259:   long ipmx;
                   3260:   double agexact;
                   3261:   /*extern weight */
                   3262:   /* We are differentiating ll according to initial status */
                   3263:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3264:   /*for(i=1;i<imx;i++) 
                   3265:     printf(" %d\n",s[4][i]);
                   3266:   */
1.162     brouard  3267: 
1.226     brouard  3268:   ++countcallfunc;
1.162     brouard  3269: 
1.226     brouard  3270:   cov[1]=1.;
1.126     brouard  3271: 
1.226     brouard  3272:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3273:   ioffset=0;
1.226     brouard  3274:   if(mle==1){
                   3275:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3276:       /* Computes the values of the ncovmodel covariates of the model
                   3277:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3278:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3279:         to be observed in j being in i according to the model.
                   3280:       */
1.243     brouard  3281:       ioffset=2+nagesqr ;
1.233     brouard  3282:    /* Fixed */
1.234     brouard  3283:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3284:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3285:       }
1.226     brouard  3286:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3287:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3288:         has been calculated etc */
                   3289:       /* For an individual i, wav[i] gives the number of effective waves */
                   3290:       /* We compute the contribution to Likelihood of each effective transition
                   3291:         mw[mi][i] is real wave of the mi th effectve wave */
                   3292:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3293:         s2=s[mw[mi+1][i]][i];
                   3294:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3295:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3296:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3297:       */
                   3298:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3299:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3300:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3301:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3302:        }
                   3303:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3304:          for (j=1;j<=nlstate+ndeath;j++){
                   3305:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3306:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3307:          }
                   3308:        for(d=0; d<dh[mi][i]; d++){
                   3309:          newm=savm;
                   3310:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3311:          cov[2]=agexact;
                   3312:          if(nagesqr==1)
                   3313:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3314:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3315:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3316:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3317:          else
                   3318:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3319:          }
                   3320:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3321:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3322:          savm=oldm;
                   3323:          oldm=newm;
                   3324:        } /* end mult */
                   3325:        
                   3326:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3327:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3328:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3329:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3330:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3331:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3332:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3333:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3334:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3335:                                 * -stepm/2 to stepm/2 .
                   3336:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3337:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3338:                                 */
1.234     brouard  3339:        s1=s[mw[mi][i]][i];
                   3340:        s2=s[mw[mi+1][i]][i];
                   3341:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3342:        /* bias bh is positive if real duration
                   3343:         * is higher than the multiple of stepm and negative otherwise.
                   3344:         */
                   3345:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3346:        if( s2 > nlstate){ 
                   3347:          /* i.e. if s2 is a death state and if the date of death is known 
                   3348:             then the contribution to the likelihood is the probability to 
                   3349:             die between last step unit time and current  step unit time, 
                   3350:             which is also equal to probability to die before dh 
                   3351:             minus probability to die before dh-stepm . 
                   3352:             In version up to 0.92 likelihood was computed
                   3353:             as if date of death was unknown. Death was treated as any other
                   3354:             health state: the date of the interview describes the actual state
                   3355:             and not the date of a change in health state. The former idea was
                   3356:             to consider that at each interview the state was recorded
                   3357:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3358:             introduced the exact date of death then we should have modified
                   3359:             the contribution of an exact death to the likelihood. This new
                   3360:             contribution is smaller and very dependent of the step unit
                   3361:             stepm. It is no more the probability to die between last interview
                   3362:             and month of death but the probability to survive from last
                   3363:             interview up to one month before death multiplied by the
                   3364:             probability to die within a month. Thanks to Chris
                   3365:             Jackson for correcting this bug.  Former versions increased
                   3366:             mortality artificially. The bad side is that we add another loop
                   3367:             which slows down the processing. The difference can be up to 10%
                   3368:             lower mortality.
                   3369:          */
                   3370:          /* If, at the beginning of the maximization mostly, the
                   3371:             cumulative probability or probability to be dead is
                   3372:             constant (ie = 1) over time d, the difference is equal to
                   3373:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3374:             s1 at precedent wave, to be dead a month before current
                   3375:             wave is equal to probability, being at state s1 at
                   3376:             precedent wave, to be dead at mont of the current
                   3377:             wave. Then the observed probability (that this person died)
                   3378:             is null according to current estimated parameter. In fact,
                   3379:             it should be very low but not zero otherwise the log go to
                   3380:             infinity.
                   3381:          */
1.183     brouard  3382: /* #ifdef INFINITYORIGINAL */
                   3383: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3384: /* #else */
                   3385: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3386: /*         lli=log(mytinydouble); */
                   3387: /*       else */
                   3388: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3389: /* #endif */
1.226     brouard  3390:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3391:          
1.226     brouard  3392:        } else if  ( s2==-1 ) { /* alive */
                   3393:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3394:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3395:          /*survp += out[s1][j]; */
                   3396:          lli= log(survp);
                   3397:        }
                   3398:        else if  (s2==-4) { 
                   3399:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3400:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3401:          lli= log(survp); 
                   3402:        } 
                   3403:        else if  (s2==-5) { 
                   3404:          for (j=1,survp=0. ; j<=2; j++)  
                   3405:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3406:          lli= log(survp); 
                   3407:        } 
                   3408:        else{
                   3409:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3410:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3411:        } 
                   3412:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3413:        /*if(lli ==000.0)*/
                   3414:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3415:        ipmx +=1;
                   3416:        sw += weight[i];
                   3417:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3418:        /* if (lli < log(mytinydouble)){ */
                   3419:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3420:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3421:        /* } */
                   3422:       } /* end of wave */
                   3423:     } /* end of individual */
                   3424:   }  else if(mle==2){
                   3425:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3426:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3427:       for(mi=1; mi<= wav[i]-1; mi++){
                   3428:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3429:          for (j=1;j<=nlstate+ndeath;j++){
                   3430:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3431:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3432:          }
                   3433:        for(d=0; d<=dh[mi][i]; d++){
                   3434:          newm=savm;
                   3435:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3436:          cov[2]=agexact;
                   3437:          if(nagesqr==1)
                   3438:            cov[3]= agexact*agexact;
                   3439:          for (kk=1; kk<=cptcovage;kk++) {
                   3440:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3441:          }
                   3442:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3443:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3444:          savm=oldm;
                   3445:          oldm=newm;
                   3446:        } /* end mult */
                   3447:       
                   3448:        s1=s[mw[mi][i]][i];
                   3449:        s2=s[mw[mi+1][i]][i];
                   3450:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3451:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3452:        ipmx +=1;
                   3453:        sw += weight[i];
                   3454:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3455:       } /* end of wave */
                   3456:     } /* end of individual */
                   3457:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3458:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3459:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3460:       for(mi=1; mi<= wav[i]-1; mi++){
                   3461:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3462:          for (j=1;j<=nlstate+ndeath;j++){
                   3463:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3464:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3465:          }
                   3466:        for(d=0; d<dh[mi][i]; d++){
                   3467:          newm=savm;
                   3468:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3469:          cov[2]=agexact;
                   3470:          if(nagesqr==1)
                   3471:            cov[3]= agexact*agexact;
                   3472:          for (kk=1; kk<=cptcovage;kk++) {
                   3473:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3474:          }
                   3475:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3476:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3477:          savm=oldm;
                   3478:          oldm=newm;
                   3479:        } /* end mult */
                   3480:       
                   3481:        s1=s[mw[mi][i]][i];
                   3482:        s2=s[mw[mi+1][i]][i];
                   3483:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3484:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3485:        ipmx +=1;
                   3486:        sw += weight[i];
                   3487:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3488:       } /* end of wave */
                   3489:     } /* end of individual */
                   3490:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3491:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3492:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3493:       for(mi=1; mi<= wav[i]-1; mi++){
                   3494:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3495:          for (j=1;j<=nlstate+ndeath;j++){
                   3496:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3497:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3498:          }
                   3499:        for(d=0; d<dh[mi][i]; d++){
                   3500:          newm=savm;
                   3501:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3502:          cov[2]=agexact;
                   3503:          if(nagesqr==1)
                   3504:            cov[3]= agexact*agexact;
                   3505:          for (kk=1; kk<=cptcovage;kk++) {
                   3506:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3507:          }
1.126     brouard  3508:        
1.226     brouard  3509:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3510:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3511:          savm=oldm;
                   3512:          oldm=newm;
                   3513:        } /* end mult */
                   3514:       
                   3515:        s1=s[mw[mi][i]][i];
                   3516:        s2=s[mw[mi+1][i]][i];
                   3517:        if( s2 > nlstate){ 
                   3518:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3519:        } else if  ( s2==-1 ) { /* alive */
                   3520:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3521:            survp += out[s1][j];
                   3522:          lli= log(survp);
                   3523:        }else{
                   3524:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3525:        }
                   3526:        ipmx +=1;
                   3527:        sw += weight[i];
                   3528:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3529: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3530:       } /* end of wave */
                   3531:     } /* end of individual */
                   3532:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3533:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3534:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3535:       for(mi=1; mi<= wav[i]-1; mi++){
                   3536:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3537:          for (j=1;j<=nlstate+ndeath;j++){
                   3538:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3539:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3540:          }
                   3541:        for(d=0; d<dh[mi][i]; d++){
                   3542:          newm=savm;
                   3543:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3544:          cov[2]=agexact;
                   3545:          if(nagesqr==1)
                   3546:            cov[3]= agexact*agexact;
                   3547:          for (kk=1; kk<=cptcovage;kk++) {
                   3548:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3549:          }
1.126     brouard  3550:        
1.226     brouard  3551:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3552:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3553:          savm=oldm;
                   3554:          oldm=newm;
                   3555:        } /* end mult */
                   3556:       
                   3557:        s1=s[mw[mi][i]][i];
                   3558:        s2=s[mw[mi+1][i]][i];
                   3559:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3560:        ipmx +=1;
                   3561:        sw += weight[i];
                   3562:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3563:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3564:       } /* end of wave */
                   3565:     } /* end of individual */
                   3566:   } /* End of if */
                   3567:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3568:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3569:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3570:   return -l;
1.126     brouard  3571: }
                   3572: 
                   3573: /*************** log-likelihood *************/
                   3574: double funcone( double *x)
                   3575: {
1.228     brouard  3576:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3577:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3578:   int ioffset=0;
1.131     brouard  3579:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3580:   double **out;
                   3581:   double lli; /* Individual log likelihood */
                   3582:   double llt;
                   3583:   int s1, s2;
1.228     brouard  3584:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3585: 
1.126     brouard  3586:   double bbh, survp;
1.187     brouard  3587:   double agexact;
1.214     brouard  3588:   double agebegin, ageend;
1.126     brouard  3589:   /*extern weight */
                   3590:   /* We are differentiating ll according to initial status */
                   3591:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3592:   /*for(i=1;i<imx;i++) 
                   3593:     printf(" %d\n",s[4][i]);
                   3594:   */
                   3595:   cov[1]=1.;
                   3596: 
                   3597:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3598:   ioffset=0;
                   3599:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3600:     /* ioffset=2+nagesqr+cptcovage; */
                   3601:     ioffset=2+nagesqr;
1.232     brouard  3602:     /* Fixed */
1.224     brouard  3603:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3604:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3605:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3606:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3607: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3608: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3609: /*    cov[2+6]=covar[2][i]; V2  */
                   3610: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3611: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3612: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3613: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3614: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3615: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3616:     }
1.232     brouard  3617:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3618:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3619:     /* } */
1.231     brouard  3620:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3621:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3622:     /* } */
1.225     brouard  3623:     
1.233     brouard  3624: 
                   3625:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3626:     /* Wave varying (but not age varying) */
                   3627:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3628:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3629:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3630:       }
1.232     brouard  3631:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3632:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3633:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3634:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3635:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3636:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3637:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3638:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3639:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3640:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3641:       /* } */
1.126     brouard  3642:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3643:        for (j=1;j<=nlstate+ndeath;j++){
                   3644:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3645:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3646:        }
1.214     brouard  3647:       
                   3648:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3649:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3650:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3651:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3652:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3653:          and mw[mi+1][i]. dh depends on stepm.*/
                   3654:        newm=savm;
1.247     brouard  3655:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3656:        cov[2]=agexact;
                   3657:        if(nagesqr==1)
                   3658:          cov[3]= agexact*agexact;
                   3659:        for (kk=1; kk<=cptcovage;kk++) {
                   3660:          if(!FixedV[Tvar[Tage[kk]]])
                   3661:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3662:          else
                   3663:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3664:        }
                   3665:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3666:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3667:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3668:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3669:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3670:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3671:        savm=oldm;
                   3672:        oldm=newm;
1.126     brouard  3673:       } /* end mult */
                   3674:       
                   3675:       s1=s[mw[mi][i]][i];
                   3676:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3677:       /* if(s2==-1){ */
                   3678:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3679:       /*       /\* exit(1); *\/ */
                   3680:       /* } */
1.126     brouard  3681:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3682:       /* bias is positive if real duration
                   3683:        * is higher than the multiple of stepm and negative otherwise.
                   3684:        */
                   3685:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3686:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3687:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3688:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3689:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3690:        lli= log(survp);
1.126     brouard  3691:       }else if (mle==1){
1.242     brouard  3692:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3693:       } else if(mle==2){
1.242     brouard  3694:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3695:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3696:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3697:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3698:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3699:       } else{  /* mle=0 back to 1 */
1.242     brouard  3700:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3701:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3702:       } /* End of if */
                   3703:       ipmx +=1;
                   3704:       sw += weight[i];
                   3705:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3706:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3707:       if(globpr){
1.246     brouard  3708:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3709:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3710:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3711:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3712:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3713:          llt +=ll[k]*gipmx/gsw;
                   3714:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3715:        }
                   3716:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3717:       }
1.232     brouard  3718:        } /* end of wave */
                   3719: } /* end of individual */
                   3720: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3721: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3722: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3723: if(globpr==0){ /* First time we count the contributions and weights */
                   3724:        gipmx=ipmx;
                   3725:        gsw=sw;
                   3726: }
                   3727: return -l;
1.126     brouard  3728: }
                   3729: 
                   3730: 
                   3731: /*************** function likelione ***********/
                   3732: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3733: {
                   3734:   /* This routine should help understanding what is done with 
                   3735:      the selection of individuals/waves and
                   3736:      to check the exact contribution to the likelihood.
                   3737:      Plotting could be done.
                   3738:    */
                   3739:   int k;
                   3740: 
                   3741:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3742:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3743:     strcat(fileresilk,fileresu);
1.126     brouard  3744:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3745:       printf("Problem with resultfile: %s\n", fileresilk);
                   3746:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3747:     }
1.214     brouard  3748:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3749:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3750:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3751:     for(k=1; k<=nlstate; k++) 
                   3752:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3753:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3754:   }
                   3755: 
                   3756:   *fretone=(*funcone)(p);
                   3757:   if(*globpri !=0){
                   3758:     fclose(ficresilk);
1.205     brouard  3759:     if (mle ==0)
                   3760:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3761:     else if(mle >=1)
                   3762:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3763:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3764:     
1.208     brouard  3765:       
                   3766:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3767:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3768: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3769:     }
1.207     brouard  3770:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3771: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3772:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3773: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3774:     fflush(fichtm);
1.205     brouard  3775:   }
1.126     brouard  3776:   return;
                   3777: }
                   3778: 
                   3779: 
                   3780: /*********** Maximum Likelihood Estimation ***************/
                   3781: 
                   3782: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3783: {
1.165     brouard  3784:   int i,j, iter=0;
1.126     brouard  3785:   double **xi;
                   3786:   double fret;
                   3787:   double fretone; /* Only one call to likelihood */
                   3788:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3789: 
                   3790: #ifdef NLOPT
                   3791:   int creturn;
                   3792:   nlopt_opt opt;
                   3793:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3794:   double *lb;
                   3795:   double minf; /* the minimum objective value, upon return */
                   3796:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3797:   myfunc_data dinst, *d = &dinst;
                   3798: #endif
                   3799: 
                   3800: 
1.126     brouard  3801:   xi=matrix(1,npar,1,npar);
                   3802:   for (i=1;i<=npar;i++)
                   3803:     for (j=1;j<=npar;j++)
                   3804:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3805:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3806:   strcpy(filerespow,"POW_"); 
1.126     brouard  3807:   strcat(filerespow,fileres);
                   3808:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3809:     printf("Problem with resultfile: %s\n", filerespow);
                   3810:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3811:   }
                   3812:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3813:   for (i=1;i<=nlstate;i++)
                   3814:     for(j=1;j<=nlstate+ndeath;j++)
                   3815:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3816:   fprintf(ficrespow,"\n");
1.162     brouard  3817: #ifdef POWELL
1.126     brouard  3818:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3819: #endif
1.126     brouard  3820: 
1.162     brouard  3821: #ifdef NLOPT
                   3822: #ifdef NEWUOA
                   3823:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3824: #else
                   3825:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3826: #endif
                   3827:   lb=vector(0,npar-1);
                   3828:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3829:   nlopt_set_lower_bounds(opt, lb);
                   3830:   nlopt_set_initial_step1(opt, 0.1);
                   3831:   
                   3832:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3833:   d->function = func;
                   3834:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3835:   nlopt_set_min_objective(opt, myfunc, d);
                   3836:   nlopt_set_xtol_rel(opt, ftol);
                   3837:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3838:     printf("nlopt failed! %d\n",creturn); 
                   3839:   }
                   3840:   else {
                   3841:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3842:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3843:     iter=1; /* not equal */
                   3844:   }
                   3845:   nlopt_destroy(opt);
                   3846: #endif
1.126     brouard  3847:   free_matrix(xi,1,npar,1,npar);
                   3848:   fclose(ficrespow);
1.203     brouard  3849:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3850:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3851:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3852: 
                   3853: }
                   3854: 
                   3855: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3856: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3857: {
                   3858:   double  **a,**y,*x,pd;
1.203     brouard  3859:   /* double **hess; */
1.164     brouard  3860:   int i, j;
1.126     brouard  3861:   int *indx;
                   3862: 
                   3863:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3864:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3865:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3866:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3867:   double gompertz(double p[]);
1.203     brouard  3868:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3869: 
                   3870:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3871:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3872:   for (i=1;i<=npar;i++){
1.203     brouard  3873:     printf("%d-",i);fflush(stdout);
                   3874:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3875:    
                   3876:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3877:     
                   3878:     /*  printf(" %f ",p[i]);
                   3879:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3880:   }
                   3881:   
                   3882:   for (i=1;i<=npar;i++) {
                   3883:     for (j=1;j<=npar;j++)  {
                   3884:       if (j>i) { 
1.203     brouard  3885:        printf(".%d-%d",i,j);fflush(stdout);
                   3886:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3887:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3888:        
                   3889:        hess[j][i]=hess[i][j];    
                   3890:        /*printf(" %lf ",hess[i][j]);*/
                   3891:       }
                   3892:     }
                   3893:   }
                   3894:   printf("\n");
                   3895:   fprintf(ficlog,"\n");
                   3896: 
                   3897:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3898:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3899:   
                   3900:   a=matrix(1,npar,1,npar);
                   3901:   y=matrix(1,npar,1,npar);
                   3902:   x=vector(1,npar);
                   3903:   indx=ivector(1,npar);
                   3904:   for (i=1;i<=npar;i++)
                   3905:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3906:   ludcmp(a,npar,indx,&pd);
                   3907: 
                   3908:   for (j=1;j<=npar;j++) {
                   3909:     for (i=1;i<=npar;i++) x[i]=0;
                   3910:     x[j]=1;
                   3911:     lubksb(a,npar,indx,x);
                   3912:     for (i=1;i<=npar;i++){ 
                   3913:       matcov[i][j]=x[i];
                   3914:     }
                   3915:   }
                   3916: 
                   3917:   printf("\n#Hessian matrix#\n");
                   3918:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3919:   for (i=1;i<=npar;i++) { 
                   3920:     for (j=1;j<=npar;j++) { 
1.203     brouard  3921:       printf("%.6e ",hess[i][j]);
                   3922:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3923:     }
                   3924:     printf("\n");
                   3925:     fprintf(ficlog,"\n");
                   3926:   }
                   3927: 
1.203     brouard  3928:   /* printf("\n#Covariance matrix#\n"); */
                   3929:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3930:   /* for (i=1;i<=npar;i++) {  */
                   3931:   /*   for (j=1;j<=npar;j++) {  */
                   3932:   /*     printf("%.6e ",matcov[i][j]); */
                   3933:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3934:   /*   } */
                   3935:   /*   printf("\n"); */
                   3936:   /*   fprintf(ficlog,"\n"); */
                   3937:   /* } */
                   3938: 
1.126     brouard  3939:   /* Recompute Inverse */
1.203     brouard  3940:   /* for (i=1;i<=npar;i++) */
                   3941:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3942:   /* ludcmp(a,npar,indx,&pd); */
                   3943: 
                   3944:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3945: 
                   3946:   /* for (j=1;j<=npar;j++) { */
                   3947:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3948:   /*   x[j]=1; */
                   3949:   /*   lubksb(a,npar,indx,x); */
                   3950:   /*   for (i=1;i<=npar;i++){  */
                   3951:   /*     y[i][j]=x[i]; */
                   3952:   /*     printf("%.3e ",y[i][j]); */
                   3953:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3954:   /*   } */
                   3955:   /*   printf("\n"); */
                   3956:   /*   fprintf(ficlog,"\n"); */
                   3957:   /* } */
                   3958: 
                   3959:   /* Verifying the inverse matrix */
                   3960: #ifdef DEBUGHESS
                   3961:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3962: 
1.203     brouard  3963:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3964:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3965: 
                   3966:   for (j=1;j<=npar;j++) {
                   3967:     for (i=1;i<=npar;i++){ 
1.203     brouard  3968:       printf("%.2f ",y[i][j]);
                   3969:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3970:     }
                   3971:     printf("\n");
                   3972:     fprintf(ficlog,"\n");
                   3973:   }
1.203     brouard  3974: #endif
1.126     brouard  3975: 
                   3976:   free_matrix(a,1,npar,1,npar);
                   3977:   free_matrix(y,1,npar,1,npar);
                   3978:   free_vector(x,1,npar);
                   3979:   free_ivector(indx,1,npar);
1.203     brouard  3980:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3981: 
                   3982: 
                   3983: }
                   3984: 
                   3985: /*************** hessian matrix ****************/
                   3986: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3987: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3988:   int i;
                   3989:   int l=1, lmax=20;
1.203     brouard  3990:   double k1,k2, res, fx;
1.132     brouard  3991:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3992:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3993:   int k=0,kmax=10;
                   3994:   double l1;
                   3995: 
                   3996:   fx=func(x);
                   3997:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3998:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3999:     l1=pow(10,l);
                   4000:     delts=delt;
                   4001:     for(k=1 ; k <kmax; k=k+1){
                   4002:       delt = delta*(l1*k);
                   4003:       p2[theta]=x[theta] +delt;
1.145     brouard  4004:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4005:       p2[theta]=x[theta]-delt;
                   4006:       k2=func(p2)-fx;
                   4007:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4008:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4009:       
1.203     brouard  4010: #ifdef DEBUGHESSII
1.126     brouard  4011:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4012:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4013: #endif
                   4014:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4015:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4016:        k=kmax;
                   4017:       }
                   4018:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4019:        k=kmax; l=lmax*10;
1.126     brouard  4020:       }
                   4021:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4022:        delts=delt;
                   4023:       }
1.203     brouard  4024:     } /* End loop k */
1.126     brouard  4025:   }
                   4026:   delti[theta]=delts;
                   4027:   return res; 
                   4028:   
                   4029: }
                   4030: 
1.203     brouard  4031: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4032: {
                   4033:   int i;
1.164     brouard  4034:   int l=1, lmax=20;
1.126     brouard  4035:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4036:   double p2[MAXPARM+1];
1.203     brouard  4037:   int k, kmax=1;
                   4038:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4039: 
                   4040:   int firstime=0;
1.203     brouard  4041:   
1.126     brouard  4042:   fx=func(x);
1.203     brouard  4043:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4044:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4045:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4046:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4047:     k1=func(p2)-fx;
                   4048:   
1.203     brouard  4049:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4050:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4051:     k2=func(p2)-fx;
                   4052:   
1.203     brouard  4053:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4054:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4055:     k3=func(p2)-fx;
                   4056:   
1.203     brouard  4057:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4058:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4059:     k4=func(p2)-fx;
1.203     brouard  4060:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4061:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4062:       firstime=1;
1.203     brouard  4063:       kmax=kmax+10;
1.208     brouard  4064:     }
                   4065:     if(kmax >=10 || firstime ==1){
1.246     brouard  4066:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4067:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4068:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4069:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4070:     }
                   4071: #ifdef DEBUGHESSIJ
                   4072:     v1=hess[thetai][thetai];
                   4073:     v2=hess[thetaj][thetaj];
                   4074:     cv12=res;
                   4075:     /* Computing eigen value of Hessian matrix */
                   4076:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4077:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4078:     if ((lc2 <0) || (lc1 <0) ){
                   4079:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4080:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4081:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4082:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4083:     }
1.126     brouard  4084: #endif
                   4085:   }
                   4086:   return res;
                   4087: }
                   4088: 
1.203     brouard  4089:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4090: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4091: /* { */
                   4092: /*   int i; */
                   4093: /*   int l=1, lmax=20; */
                   4094: /*   double k1,k2,k3,k4,res,fx; */
                   4095: /*   double p2[MAXPARM+1]; */
                   4096: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4097: /*   int k=0,kmax=10; */
                   4098: /*   double l1; */
                   4099:   
                   4100: /*   fx=func(x); */
                   4101: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4102: /*     l1=pow(10,l); */
                   4103: /*     delts=delt; */
                   4104: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4105: /*       delt = delti*(l1*k); */
                   4106: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4107: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4108: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4109: /*       k1=func(p2)-fx; */
                   4110:       
                   4111: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4112: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4113: /*       k2=func(p2)-fx; */
                   4114:       
                   4115: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4116: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4117: /*       k3=func(p2)-fx; */
                   4118:       
                   4119: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4120: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4121: /*       k4=func(p2)-fx; */
                   4122: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4123: /* #ifdef DEBUGHESSIJ */
                   4124: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4125: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4126: /* #endif */
                   4127: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4128: /*     k=kmax; */
                   4129: /*       } */
                   4130: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4131: /*     k=kmax; l=lmax*10; */
                   4132: /*       } */
                   4133: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4134: /*     delts=delt; */
                   4135: /*       } */
                   4136: /*     } /\* End loop k *\/ */
                   4137: /*   } */
                   4138: /*   delti[theta]=delts; */
                   4139: /*   return res;  */
                   4140: /* } */
                   4141: 
                   4142: 
1.126     brouard  4143: /************** Inverse of matrix **************/
                   4144: void ludcmp(double **a, int n, int *indx, double *d) 
                   4145: { 
                   4146:   int i,imax,j,k; 
                   4147:   double big,dum,sum,temp; 
                   4148:   double *vv; 
                   4149:  
                   4150:   vv=vector(1,n); 
                   4151:   *d=1.0; 
                   4152:   for (i=1;i<=n;i++) { 
                   4153:     big=0.0; 
                   4154:     for (j=1;j<=n;j++) 
                   4155:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4156:     if (big == 0.0){
                   4157:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4158:       for (j=1;j<=n;j++) {
                   4159:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4160:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4161:       }
                   4162:       fflush(ficlog);
                   4163:       fclose(ficlog);
                   4164:       nrerror("Singular matrix in routine ludcmp"); 
                   4165:     }
1.126     brouard  4166:     vv[i]=1.0/big; 
                   4167:   } 
                   4168:   for (j=1;j<=n;j++) { 
                   4169:     for (i=1;i<j;i++) { 
                   4170:       sum=a[i][j]; 
                   4171:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4172:       a[i][j]=sum; 
                   4173:     } 
                   4174:     big=0.0; 
                   4175:     for (i=j;i<=n;i++) { 
                   4176:       sum=a[i][j]; 
                   4177:       for (k=1;k<j;k++) 
                   4178:        sum -= a[i][k]*a[k][j]; 
                   4179:       a[i][j]=sum; 
                   4180:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4181:        big=dum; 
                   4182:        imax=i; 
                   4183:       } 
                   4184:     } 
                   4185:     if (j != imax) { 
                   4186:       for (k=1;k<=n;k++) { 
                   4187:        dum=a[imax][k]; 
                   4188:        a[imax][k]=a[j][k]; 
                   4189:        a[j][k]=dum; 
                   4190:       } 
                   4191:       *d = -(*d); 
                   4192:       vv[imax]=vv[j]; 
                   4193:     } 
                   4194:     indx[j]=imax; 
                   4195:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4196:     if (j != n) { 
                   4197:       dum=1.0/(a[j][j]); 
                   4198:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4199:     } 
                   4200:   } 
                   4201:   free_vector(vv,1,n);  /* Doesn't work */
                   4202: ;
                   4203: } 
                   4204: 
                   4205: void lubksb(double **a, int n, int *indx, double b[]) 
                   4206: { 
                   4207:   int i,ii=0,ip,j; 
                   4208:   double sum; 
                   4209:  
                   4210:   for (i=1;i<=n;i++) { 
                   4211:     ip=indx[i]; 
                   4212:     sum=b[ip]; 
                   4213:     b[ip]=b[i]; 
                   4214:     if (ii) 
                   4215:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4216:     else if (sum) ii=i; 
                   4217:     b[i]=sum; 
                   4218:   } 
                   4219:   for (i=n;i>=1;i--) { 
                   4220:     sum=b[i]; 
                   4221:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4222:     b[i]=sum/a[i][i]; 
                   4223:   } 
                   4224: } 
                   4225: 
                   4226: void pstamp(FILE *fichier)
                   4227: {
1.196     brouard  4228:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4229: }
                   4230: 
1.253     brouard  4231: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4232: 
                   4233:   /* y=a+bx regression */
                   4234:   double   sumx = 0.0;                        /* sum of x                      */
                   4235:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4236:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4237:   double   sumy = 0.0;                        /* sum of y                      */
                   4238:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4239:   double   sume2; /* sum of square or residuals */
                   4240:   double yhat;
                   4241:   
                   4242:   double denom=0;
                   4243:   int i;
                   4244:   int ne=*no;
                   4245:   
                   4246:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4247:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4248:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4249:       continue;
                   4250:     }
                   4251:     ne=ne+1;
                   4252:     sumx  += x[i];       
                   4253:     sumx2 += x[i]*x[i];  
                   4254:     sumxy += x[i] * y[i];
                   4255:     sumy  += y[i];      
                   4256:     sumy2 += y[i]*y[i]; 
                   4257:     denom = (ne * sumx2 - sumx*sumx);
                   4258:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4259:   } 
                   4260:   
                   4261:   denom = (ne * sumx2 - sumx*sumx);
                   4262:   if (denom == 0) {
                   4263:     // vertical, slope m is infinity
                   4264:     *b = INFINITY;
                   4265:     *a = 0;
                   4266:     if (r) *r = 0;
                   4267:     return 1;
                   4268:   }
                   4269:   
                   4270:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4271:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4272:   if (r!=NULL) {
                   4273:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4274:       sqrt((sumx2 - sumx*sumx/ne) *
                   4275:           (sumy2 - sumy*sumy/ne));
                   4276:   }
                   4277:   *no=ne;
                   4278:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4279:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4280:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4281:       continue;
                   4282:     }
                   4283:     ne=ne+1;
                   4284:     yhat = y[i] - *a -*b* x[i];
                   4285:     sume2  += yhat * yhat ;       
                   4286:     
                   4287:     denom = (ne * sumx2 - sumx*sumx);
                   4288:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4289:   } 
                   4290:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4291:   *sa= *sb * sqrt(sumx2/ne);
                   4292:   
                   4293:   return 0; 
                   4294: }
                   4295: 
1.126     brouard  4296: /************ Frequencies ********************/
1.251     brouard  4297: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4298:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4299:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4300: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4301:   
1.253     brouard  4302:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4303:   int iind=0, iage=0;
                   4304:   int mi; /* Effective wave */
                   4305:   int first;
                   4306:   double ***freq; /* Frequencies */
1.253     brouard  4307:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4308:   int no;
1.226     brouard  4309:   double *meanq;
                   4310:   double **meanqt;
                   4311:   double *pp, **prop, *posprop, *pospropt;
                   4312:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4313:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4314:   double agebegin, ageend;
                   4315:     
                   4316:   pp=vector(1,nlstate);
1.251     brouard  4317:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4318:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4319:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4320:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4321:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4322:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4323:   strcpy(fileresp,"P_");
                   4324:   strcat(fileresp,fileresu);
                   4325:   /*strcat(fileresphtm,fileresu);*/
                   4326:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4327:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4328:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4329:     exit(0);
                   4330:   }
1.240     brouard  4331:   
1.226     brouard  4332:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4333:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4334:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4335:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4336:     fflush(ficlog);
                   4337:     exit(70); 
                   4338:   }
                   4339:   else{
                   4340:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4341: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4342: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4343:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4344:   }
1.237     brouard  4345:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4346:   
1.226     brouard  4347:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4348:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4349:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4350:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4351:     fflush(ficlog);
                   4352:     exit(70); 
1.240     brouard  4353:   } else{
1.226     brouard  4354:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4355: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4356: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4357:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4358:   }
1.240     brouard  4359:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4360:   
1.253     brouard  4361:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4362:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4363:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4364:   j1=0;
1.126     brouard  4365:   
1.227     brouard  4366:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4367:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4368:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4369:   
                   4370:   
1.226     brouard  4371:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4372:      reference=low_education V1=0,V2=0
                   4373:      med_educ                V1=1 V2=0, 
                   4374:      high_educ               V1=0 V2=1
                   4375:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4376:   */
1.249     brouard  4377:   dateintsum=0;
                   4378:   k2cpt=0;
                   4379: 
1.253     brouard  4380:   if(cptcoveff == 0 )
                   4381:     nl=1;  /* Constant model only */
                   4382:   else
                   4383:     nl=2;
                   4384:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4385:     if(nj==1)
                   4386:       j=0;  /* First pass for the constant */
                   4387:     else
                   4388:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4389:     first=1;
                   4390:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4391:       posproptt=0.;
                   4392:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4393:        scanf("%d", i);*/
                   4394:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4395:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4396:          for(m=iagemin; m <= iagemax+3; m++)
                   4397:            freq[i][jk][m]=0;
                   4398:       
                   4399:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4400:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4401:          prop[i][m]=0;
                   4402:        posprop[i]=0;
                   4403:        pospropt[i]=0;
                   4404:       }
                   4405:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4406:       /*   meanq[z1]+=0.; */
                   4407:       /*   for(m=1;m<=lastpass;m++){ */
                   4408:       /*       meanqt[m][z1]=0.; */
                   4409:       /*   } */
                   4410:       /* } */
                   4411:       
                   4412:       /* dateintsum=0; */
                   4413:       /* k2cpt=0; */
                   4414:       
                   4415:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4416:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4417:        bool=1;
                   4418:        if(j !=0){
                   4419:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4420:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4421:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4422:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4423:              /* } */
                   4424:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4425:                /* if(Tvaraff[z1] ==-20){ */
                   4426:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4427:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4428:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4429:                /* }else  */
                   4430:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4431:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4432:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4433:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4434:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4435:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4436:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4437:                } /* Onlyf fixed */
                   4438:              } /* end z1 */
                   4439:            } /* cptcovn > 0 */
                   4440:          } /* end any */
                   4441:        }/* end j==0 */
                   4442:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4443:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4444:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4445:            m=mw[mi][iind];
                   4446:            if(j!=0){
                   4447:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4448:                for (z1=1; z1<=cptcoveff; z1++) {
                   4449:                  if( Fixed[Tmodelind[z1]]==1){
                   4450:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4451:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4452:                                                                                      value is -1, we don't select. It differs from the 
                   4453:                                                                                      constant and age model which counts them. */
                   4454:                      bool=0; /* not selected */
                   4455:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4456:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4457:                      bool=0;
                   4458:                    }
                   4459:                  }
                   4460:                }
                   4461:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4462:            } /* end j==0 */
                   4463:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4464:            if(bool==1){
                   4465:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4466:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4467:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4468:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4469:              if(m >=firstpass && m <=lastpass){
                   4470:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4471:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4472:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4473:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4474:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4475:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4476:                if (m<lastpass) {
                   4477:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4478:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4479:                  if(s[m][iind]==-1)
                   4480:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4481:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4482:                  /* if((int)agev[m][iind] == 55) */
                   4483:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4484:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4485:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4486:                }
1.251     brouard  4487:              } /* end if between passes */  
                   4488:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4489:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4490:                k2cpt++;
                   4491:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4492:              }
1.251     brouard  4493:            }else{
                   4494:              bool=1;
                   4495:            }/* end bool 2 */
                   4496:          } /* end m */
                   4497:        } /* end bool */
                   4498:       } /* end iind = 1 to imx */
                   4499:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4500:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4501:       
                   4502:       
                   4503:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4504:       pstamp(ficresp);
                   4505:       if  (cptcoveff>0 && j!=0){
                   4506:        printf( "\n#********** Variable "); 
                   4507:        fprintf(ficresp, "\n#********** Variable "); 
                   4508:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4509:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4510:        fprintf(ficlog, "\n#********** Variable "); 
                   4511:        for (z1=1; z1<=cptcoveff; z1++){
                   4512:          if(!FixedV[Tvaraff[z1]]){
                   4513:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4514:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4515:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4516:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4517:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4518:          }else{
1.251     brouard  4519:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4520:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4521:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4522:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4523:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4524:          }
                   4525:        }
                   4526:        printf( "**********\n#");
                   4527:        fprintf(ficresp, "**********\n#");
                   4528:        fprintf(ficresphtm, "**********</h3>\n");
                   4529:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4530:        fprintf(ficlog, "**********\n");
                   4531:       }
                   4532:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4533:       for(i=1; i<=nlstate;i++) {
                   4534:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4535:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4536:       }
                   4537:       fprintf(ficresp, "\n");
                   4538:       fprintf(ficresphtm, "\n");
                   4539:       
                   4540:       /* Header of frequency table by age */
                   4541:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4542:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4543:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4544:        for(m=-1; m <=nlstate+ndeath; m++){
                   4545:          if(jk!=0 && m!=0)
                   4546:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4547:        }
1.226     brouard  4548:       }
1.251     brouard  4549:       fprintf(ficresphtmfr, "\n");
                   4550:     
                   4551:       /* For each age */
                   4552:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4553:        fprintf(ficresphtm,"<tr>");
                   4554:        if(iage==iagemax+1){
                   4555:          fprintf(ficlog,"1");
                   4556:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4557:        }else if(iage==iagemax+2){
                   4558:          fprintf(ficlog,"0");
                   4559:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4560:        }else if(iage==iagemax+3){
                   4561:          fprintf(ficlog,"Total");
                   4562:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4563:        }else{
1.240     brouard  4564:          if(first==1){
1.251     brouard  4565:            first=0;
                   4566:            printf("See log file for details...\n");
                   4567:          }
                   4568:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4569:          fprintf(ficlog,"Age %d", iage);
                   4570:        }
                   4571:        for(jk=1; jk <=nlstate ; jk++){
                   4572:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4573:            pp[jk] += freq[jk][m][iage]; 
                   4574:        }
                   4575:        for(jk=1; jk <=nlstate ; jk++){
                   4576:          for(m=-1, pos=0; m <=0 ; m++)
                   4577:            pos += freq[jk][m][iage];
                   4578:          if(pp[jk]>=1.e-10){
                   4579:            if(first==1){
                   4580:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4581:            }
                   4582:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4583:          }else{
                   4584:            if(first==1)
                   4585:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4586:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4587:          }
                   4588:        }
                   4589:       
1.251     brouard  4590:        for(jk=1; jk <=nlstate ; jk++){ 
                   4591:          /* posprop[jk]=0; */
                   4592:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4593:            pp[jk] += freq[jk][m][iage];
                   4594:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4595:       
                   4596:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4597:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4598:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4599:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4600:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4601:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4602:        }
1.251     brouard  4603:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4604:          if(pos>=1.e-5){
1.251     brouard  4605:            if(first==1)
                   4606:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4607:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4608:          }else{
                   4609:            if(first==1)
                   4610:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4611:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4612:          }
                   4613:          if( iage <= iagemax){
                   4614:            if(pos>=1.e-5){
                   4615:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4616:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4617:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4618:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4619:            }
                   4620:            else{
                   4621:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4622:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4623:            }
1.240     brouard  4624:          }
1.251     brouard  4625:          pospropt[jk] +=posprop[jk];
                   4626:        } /* end loop jk */
                   4627:        /* pospropt=0.; */
                   4628:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4629:          for(m=-1; m <=nlstate+ndeath; m++){
                   4630:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4631:              if(first==1){
                   4632:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4633:              }
1.253     brouard  4634:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4635:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4636:            }
                   4637:            if(jk!=0 && m!=0)
                   4638:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4639:          }
1.251     brouard  4640:        } /* end loop jk */
                   4641:        posproptt=0.; 
                   4642:        for(jk=1; jk <=nlstate; jk++){
                   4643:          posproptt += pospropt[jk];
                   4644:        }
                   4645:        fprintf(ficresphtmfr,"</tr>\n ");
                   4646:        if(iage <= iagemax){
                   4647:          fprintf(ficresp,"\n");
                   4648:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4649:        }
1.251     brouard  4650:        if(first==1)
                   4651:          printf("Others in log...\n");
                   4652:        fprintf(ficlog,"\n");
                   4653:       } /* end loop age iage */
                   4654:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4655:       for(jk=1; jk <=nlstate ; jk++){
                   4656:        if(posproptt < 1.e-5){
                   4657:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4658:        }else{
                   4659:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4660:        }
1.226     brouard  4661:       }
1.251     brouard  4662:       fprintf(ficresphtm,"</tr>\n");
                   4663:       fprintf(ficresphtm,"</table>\n");
                   4664:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4665:       if(posproptt < 1.e-5){
1.251     brouard  4666:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4667:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4668:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4669:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4670:        invalidvarcomb[j1]=1;
1.226     brouard  4671:       }else{
1.251     brouard  4672:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4673:        invalidvarcomb[j1]=0;
1.226     brouard  4674:       }
1.251     brouard  4675:       fprintf(ficresphtmfr,"</table>\n");
                   4676:       fprintf(ficlog,"\n");
                   4677:       if(j!=0){
                   4678:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4679:        for(i=1,jk=1; i <=nlstate; i++){
                   4680:          for(k=1; k <=(nlstate+ndeath); k++){
                   4681:            if (k != i) {
                   4682:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4683:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4684:                  if(j1==1){ /* All dummy covariates to zero */
                   4685:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4686:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4687:                    printf("%d%d ",i,k);
                   4688:                    fprintf(ficlog,"%d%d ",i,k);
                   4689:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4690:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4691:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4692:                  }
1.253     brouard  4693:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4694:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4695:                    x[iage]= (double)iage;
                   4696:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4697:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4698:                  }
                   4699:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4700:                  pstart[jk]=b;
                   4701:                  pstart[jk-1]=a;
1.252     brouard  4702:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4703:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4704:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4705:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4706:                  printf("%d%d ",i,k);
                   4707:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4708:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4709:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4710:                  ;
                   4711:                }
                   4712:                /* printf("%12.7f )", param[i][jj][k]); */
                   4713:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4714:                jk++; 
                   4715:              } /* end jj */
                   4716:            } /* end k!= i */
                   4717:          } /* end k */
                   4718:        } /* end i, jk */
                   4719:       } /* end j !=0 */
                   4720:     } /* end selected combination of covariate j1 */
                   4721:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4722:       printf("#Freqsummary: Starting values for the constants:\n");
                   4723:       fprintf(ficlog,"\n");
                   4724:       for(i=1,jk=1; i <=nlstate; i++){
                   4725:        for(k=1; k <=(nlstate+ndeath); k++){
                   4726:          if (k != i) {
                   4727:            printf("%d%d ",i,k);
                   4728:            fprintf(ficlog,"%d%d ",i,k);
                   4729:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4730:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4731:              if(jj==1){ /* Age has to be done */
                   4732:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4733:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4734:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4735:              }
                   4736:              /* printf("%12.7f )", param[i][jj][k]); */
                   4737:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4738:              jk++; 
1.250     brouard  4739:            }
1.251     brouard  4740:            printf("\n");
                   4741:            fprintf(ficlog,"\n");
1.250     brouard  4742:          }
                   4743:        }
                   4744:       }
1.251     brouard  4745:       printf("#Freqsummary\n");
                   4746:       fprintf(ficlog,"\n");
                   4747:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4748:        for(m=-1; m <=nlstate+ndeath; m++){
                   4749:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4750:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4751:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4752:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4753:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4754:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4755:          /* } */
                   4756:        }
                   4757:       } /* end loop jk */
                   4758:       
                   4759:       printf("\n");
                   4760:       fprintf(ficlog,"\n");
                   4761:     } /* end j=0 */
1.249     brouard  4762:   } /* end j */
1.252     brouard  4763: 
1.253     brouard  4764:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4765:     for(i=1, jk=1; i <=nlstate; i++){
                   4766:       for(j=1; j <=nlstate+ndeath; j++){
                   4767:        if(j!=i){
                   4768:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4769:          printf("%1d%1d",i,j);
                   4770:          fprintf(ficparo,"%1d%1d",i,j);
                   4771:          for(k=1; k<=ncovmodel;k++){
                   4772:            /*    printf(" %lf",param[i][j][k]); */
                   4773:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4774:            p[jk]=pstart[jk];
                   4775:            printf(" %f ",pstart[jk]);
                   4776:            fprintf(ficparo," %f ",pstart[jk]);
                   4777:            jk++;
                   4778:          }
                   4779:          printf("\n");
                   4780:          fprintf(ficparo,"\n");
                   4781:        }
                   4782:       }
                   4783:     }
                   4784:   } /* end mle=-2 */
1.226     brouard  4785:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4786:   
1.226     brouard  4787:   fclose(ficresp);
                   4788:   fclose(ficresphtm);
                   4789:   fclose(ficresphtmfr);
                   4790:   free_vector(meanq,1,nqfveff);
                   4791:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4792:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4793:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4794:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4795:   free_vector(pospropt,1,nlstate);
                   4796:   free_vector(posprop,1,nlstate);
1.251     brouard  4797:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4798:   free_vector(pp,1,nlstate);
                   4799:   /* End of freqsummary */
                   4800: }
1.126     brouard  4801: 
                   4802: /************ Prevalence ********************/
1.227     brouard  4803: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4804: {  
                   4805:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4806:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4807:      We still use firstpass and lastpass as another selection.
                   4808:   */
1.126     brouard  4809:  
1.227     brouard  4810:   int i, m, jk, j1, bool, z1,j, iv;
                   4811:   int mi; /* Effective wave */
                   4812:   int iage;
                   4813:   double agebegin, ageend;
                   4814: 
                   4815:   double **prop;
                   4816:   double posprop; 
                   4817:   double  y2; /* in fractional years */
                   4818:   int iagemin, iagemax;
                   4819:   int first; /** to stop verbosity which is redirected to log file */
                   4820: 
                   4821:   iagemin= (int) agemin;
                   4822:   iagemax= (int) agemax;
                   4823:   /*pp=vector(1,nlstate);*/
1.251     brouard  4824:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4825:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4826:   j1=0;
1.222     brouard  4827:   
1.227     brouard  4828:   /*j=cptcoveff;*/
                   4829:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4830:   
1.227     brouard  4831:   first=1;
                   4832:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4833:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4834:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4835:        prop[i][iage]=0.0;
                   4836:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4837:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4838:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4839:     
                   4840:     for (i=1; i<=imx; i++) { /* Each individual */
                   4841:       bool=1;
                   4842:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4843:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4844:        m=mw[mi][i];
                   4845:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4846:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4847:        for (z1=1; z1<=cptcoveff; z1++){
                   4848:          if( Fixed[Tmodelind[z1]]==1){
                   4849:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4850:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4851:              bool=0;
                   4852:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4853:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4854:              bool=0;
                   4855:            }
                   4856:        }
                   4857:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4858:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4859:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4860:          if(m >=firstpass && m <=lastpass){
                   4861:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4862:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4863:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4864:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4865:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4866:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4867:                exit(1);
                   4868:              }
                   4869:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4870:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4871:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4872:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4873:              } /* end valid statuses */ 
                   4874:            } /* end selection of dates */
                   4875:          } /* end selection of waves */
                   4876:        } /* end bool */
                   4877:       } /* end wave */
                   4878:     } /* end individual */
                   4879:     for(i=iagemin; i <= iagemax+3; i++){  
                   4880:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4881:        posprop += prop[jk][i]; 
                   4882:       } 
                   4883:       
                   4884:       for(jk=1; jk <=nlstate ; jk++){      
                   4885:        if( i <=  iagemax){ 
                   4886:          if(posprop>=1.e-5){ 
                   4887:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4888:          } else{
                   4889:            if(first==1){
                   4890:              first=0;
                   4891:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4892:            }
                   4893:          }
                   4894:        } 
                   4895:       }/* end jk */ 
                   4896:     }/* end i */ 
1.222     brouard  4897:      /*} *//* end i1 */
1.227     brouard  4898:   } /* end j1 */
1.222     brouard  4899:   
1.227     brouard  4900:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4901:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4902:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4903: }  /* End of prevalence */
1.126     brouard  4904: 
                   4905: /************* Waves Concatenation ***************/
                   4906: 
                   4907: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4908: {
                   4909:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4910:      Death is a valid wave (if date is known).
                   4911:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4912:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4913:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4914:   */
1.126     brouard  4915: 
1.224     brouard  4916:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4917:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4918:      double sum=0., jmean=0.;*/
1.224     brouard  4919:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4920:   int j, k=0,jk, ju, jl;
                   4921:   double sum=0.;
                   4922:   first=0;
1.214     brouard  4923:   firstwo=0;
1.217     brouard  4924:   firsthree=0;
1.218     brouard  4925:   firstfour=0;
1.164     brouard  4926:   jmin=100000;
1.126     brouard  4927:   jmax=-1;
                   4928:   jmean=0.;
1.224     brouard  4929: 
                   4930: /* Treating live states */
1.214     brouard  4931:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4932:     mi=0;  /* First valid wave */
1.227     brouard  4933:     mli=0; /* Last valid wave */
1.126     brouard  4934:     m=firstpass;
1.214     brouard  4935:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4936:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4937:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4938:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4939:        mw[++mi][i]=m;
                   4940:        mli=m;
1.224     brouard  4941:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4942:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4943:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4944:       }
1.227     brouard  4945:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4946: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4947:        break;
1.224     brouard  4948: #else
1.227     brouard  4949:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4950:          if(firsthree == 0){
1.262   ! brouard  4951:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4952:            firsthree=1;
                   4953:          }
1.262   ! brouard  4954:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4955:          mw[++mi][i]=m;
                   4956:          mli=m;
                   4957:        }
                   4958:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4959:          nbwarn++;
                   4960:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4961:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4962:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4963:          }
                   4964:          break;
                   4965:        }
                   4966:        break;
1.224     brouard  4967: #endif
1.227     brouard  4968:       }/* End m >= lastpass */
1.126     brouard  4969:     }/* end while */
1.224     brouard  4970: 
1.227     brouard  4971:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4972:     /* After last pass */
1.224     brouard  4973: /* Treating death states */
1.214     brouard  4974:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4975:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4976:       /* } */
1.126     brouard  4977:       mi++;    /* Death is another wave */
                   4978:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4979:       /* Only death is a correct wave */
1.126     brouard  4980:       mw[mi][i]=m;
1.257     brouard  4981:     } /* else not in a death state */
1.224     brouard  4982: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4983:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4984:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4985:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4986:          nbwarn++;
                   4987:          if(firstfiv==0){
                   4988:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4989:            firstfiv=1;
                   4990:          }else{
                   4991:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4992:          }
                   4993:        }else{ /* Death occured afer last wave potential bias */
                   4994:          nberr++;
                   4995:          if(firstwo==0){
1.257     brouard  4996:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4997:            firstwo=1;
                   4998:          }
1.257     brouard  4999:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5000:        }
1.257     brouard  5001:       }else{ /* if date of interview is unknown */
1.227     brouard  5002:        /* death is known but not confirmed by death status at any wave */
                   5003:        if(firstfour==0){
                   5004:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5005:          firstfour=1;
                   5006:        }
                   5007:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5008:       }
1.224     brouard  5009:     } /* end if date of death is known */
                   5010: #endif
                   5011:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5012:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5013:     if(mi==0){
                   5014:       nbwarn++;
                   5015:       if(first==0){
1.227     brouard  5016:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5017:        first=1;
1.126     brouard  5018:       }
                   5019:       if(first==1){
1.227     brouard  5020:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5021:       }
                   5022:     } /* end mi==0 */
                   5023:   } /* End individuals */
1.214     brouard  5024:   /* wav and mw are no more changed */
1.223     brouard  5025:        
1.214     brouard  5026:   
1.126     brouard  5027:   for(i=1; i<=imx; i++){
                   5028:     for(mi=1; mi<wav[i];mi++){
                   5029:       if (stepm <=0)
1.227     brouard  5030:        dh[mi][i]=1;
1.126     brouard  5031:       else{
1.260     brouard  5032:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5033:          if (agedc[i] < 2*AGESUP) {
                   5034:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5035:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5036:            else if(j<0){
                   5037:              nberr++;
                   5038:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5039:              j=1; /* Temporary Dangerous patch */
                   5040:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5041:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5042:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5043:            }
                   5044:            k=k+1;
                   5045:            if (j >= jmax){
                   5046:              jmax=j;
                   5047:              ijmax=i;
                   5048:            }
                   5049:            if (j <= jmin){
                   5050:              jmin=j;
                   5051:              ijmin=i;
                   5052:            }
                   5053:            sum=sum+j;
                   5054:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5055:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5056:          }
                   5057:        }
                   5058:        else{
                   5059:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5060: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5061:                                        
1.227     brouard  5062:          k=k+1;
                   5063:          if (j >= jmax) {
                   5064:            jmax=j;
                   5065:            ijmax=i;
                   5066:          }
                   5067:          else if (j <= jmin){
                   5068:            jmin=j;
                   5069:            ijmin=i;
                   5070:          }
                   5071:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5072:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5073:          if(j<0){
                   5074:            nberr++;
                   5075:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5076:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5077:          }
                   5078:          sum=sum+j;
                   5079:        }
                   5080:        jk= j/stepm;
                   5081:        jl= j -jk*stepm;
                   5082:        ju= j -(jk+1)*stepm;
                   5083:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5084:          if(jl==0){
                   5085:            dh[mi][i]=jk;
                   5086:            bh[mi][i]=0;
                   5087:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5088:                  * to avoid the price of an extra matrix product in likelihood */
                   5089:            dh[mi][i]=jk+1;
                   5090:            bh[mi][i]=ju;
                   5091:          }
                   5092:        }else{
                   5093:          if(jl <= -ju){
                   5094:            dh[mi][i]=jk;
                   5095:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5096:                                 * is higher than the multiple of stepm and negative otherwise.
                   5097:                                 */
                   5098:          }
                   5099:          else{
                   5100:            dh[mi][i]=jk+1;
                   5101:            bh[mi][i]=ju;
                   5102:          }
                   5103:          if(dh[mi][i]==0){
                   5104:            dh[mi][i]=1; /* At least one step */
                   5105:            bh[mi][i]=ju; /* At least one step */
                   5106:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5107:          }
                   5108:        } /* end if mle */
1.126     brouard  5109:       }
                   5110:     } /* end wave */
                   5111:   }
                   5112:   jmean=sum/k;
                   5113:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5114:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5115: }
1.126     brouard  5116: 
                   5117: /*********** Tricode ****************************/
1.220     brouard  5118:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5119:  {
                   5120:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5121:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5122:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5123:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5124:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5125:     */
1.130     brouard  5126: 
1.242     brouard  5127:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5128:    int modmaxcovj=0; /* Modality max of covariates j */
                   5129:    int cptcode=0; /* Modality max of covariates j */
                   5130:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5131: 
                   5132: 
1.242     brouard  5133:    /* cptcoveff=0;  */
                   5134:    /* *cptcov=0; */
1.126     brouard  5135:  
1.242     brouard  5136:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5137: 
1.242     brouard  5138:    /* Loop on covariates without age and products and no quantitative variable */
                   5139:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5140:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5141:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5142:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5143:        switch(Fixed[k]) {
                   5144:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5145:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5146:           ij=(int)(covar[Tvar[k]][i]);
                   5147:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5148:            * If product of Vn*Vm, still boolean *:
                   5149:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5150:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5151:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5152:              modality of the nth covariate of individual i. */
                   5153:           if (ij > modmaxcovj)
                   5154:             modmaxcovj=ij; 
                   5155:           else if (ij < modmincovj) 
                   5156:             modmincovj=ij; 
                   5157:           if ((ij < -1) && (ij > NCOVMAX)){
                   5158:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5159:             exit(1);
                   5160:           }else
                   5161:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5162:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5163:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5164:           /* getting the maximum value of the modality of the covariate
                   5165:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5166:              female ies 1, then modmaxcovj=1.
                   5167:           */
                   5168:         } /* end for loop on individuals i */
                   5169:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5170:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5171:         cptcode=modmaxcovj;
                   5172:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5173:         /*for (i=0; i<=cptcode; i++) {*/
                   5174:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5175:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5176:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5177:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5178:             if( j != -1){
                   5179:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5180:                                  covariate for which somebody answered excluding 
                   5181:                                  undefined. Usually 2: 0 and 1. */
                   5182:             }
                   5183:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5184:                                     covariate for which somebody answered including 
                   5185:                                     undefined. Usually 3: -1, 0 and 1. */
                   5186:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5187:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5188:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5189:                        
1.242     brouard  5190:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5191:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5192:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5193:         /* modmincovj=3; modmaxcovj = 7; */
                   5194:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5195:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5196:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5197:         /* nbcode[Tvar[j]][ij]=k; */
                   5198:         /* nbcode[Tvar[j]][1]=0; */
                   5199:         /* nbcode[Tvar[j]][2]=1; */
                   5200:         /* nbcode[Tvar[j]][3]=2; */
                   5201:         /* To be continued (not working yet). */
                   5202:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5203:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5204:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5205:             break;
                   5206:           }
                   5207:           ij++;
                   5208:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5209:           cptcode = ij; /* New max modality for covar j */
                   5210:         } /* end of loop on modality i=-1 to 1 or more */
                   5211:         break;
                   5212:        case 1: /* Testing on varying covariate, could be simple and
                   5213:                * should look at waves or product of fixed *
                   5214:                * varying. No time to test -1, assuming 0 and 1 only */
                   5215:         ij=0;
                   5216:         for(i=0; i<=1;i++){
                   5217:           nbcode[Tvar[k]][++ij]=i;
                   5218:         }
                   5219:         break;
                   5220:        default:
                   5221:         break;
                   5222:        } /* end switch */
                   5223:      } /* end dummy test */
                   5224:     
                   5225:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5226:      /*        /\*recode from 0 *\/ */
                   5227:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5228:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5229:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5230:      /*        } */
                   5231:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5232:      /*        if (ij > ncodemax[j]) { */
                   5233:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5234:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5235:      /*          break; */
                   5236:      /*        } */
                   5237:      /*   }  /\* end of loop on modality k *\/ */
                   5238:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5239:   
                   5240:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5241:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5242:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5243:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5244:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5245:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5246:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5247:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5248:   
                   5249:    ij=0;
                   5250:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5251:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5252:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5253:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5254:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5255:        /* If product not in single variable we don't print results */
                   5256:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5257:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5258:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5259:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5260:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5261:        if(Fixed[k]!=0)
                   5262:         anyvaryingduminmodel=1;
                   5263:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5264:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5265:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5266:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5267:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5268:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5269:      } 
                   5270:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5271:    /* ij--; */
                   5272:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5273:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5274:                * because they can be excluded from the model and real
                   5275:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5276:    for(j=ij+1; j<= cptcovt; j++){
                   5277:      Tvaraff[j]=0;
                   5278:      Tmodelind[j]=0;
                   5279:    }
                   5280:    for(j=ntveff+1; j<= cptcovt; j++){
                   5281:      TmodelInvind[j]=0;
                   5282:    }
                   5283:    /* To be sorted */
                   5284:    ;
                   5285:  }
1.126     brouard  5286: 
1.145     brouard  5287: 
1.126     brouard  5288: /*********** Health Expectancies ****************/
                   5289: 
1.235     brouard  5290:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5291: 
                   5292: {
                   5293:   /* Health expectancies, no variances */
1.164     brouard  5294:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5295:   int nhstepma, nstepma; /* Decreasing with age */
                   5296:   double age, agelim, hf;
                   5297:   double ***p3mat;
                   5298:   double eip;
                   5299: 
1.238     brouard  5300:   /* pstamp(ficreseij); */
1.126     brouard  5301:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5302:   fprintf(ficreseij,"# Age");
                   5303:   for(i=1; i<=nlstate;i++){
                   5304:     for(j=1; j<=nlstate;j++){
                   5305:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5306:     }
                   5307:     fprintf(ficreseij," e%1d. ",i);
                   5308:   }
                   5309:   fprintf(ficreseij,"\n");
                   5310: 
                   5311:   
                   5312:   if(estepm < stepm){
                   5313:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5314:   }
                   5315:   else  hstepm=estepm;   
                   5316:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5317:    * This is mainly to measure the difference between two models: for example
                   5318:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5319:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5320:    * progression in between and thus overestimating or underestimating according
                   5321:    * to the curvature of the survival function. If, for the same date, we 
                   5322:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5323:    * to compare the new estimate of Life expectancy with the same linear 
                   5324:    * hypothesis. A more precise result, taking into account a more precise
                   5325:    * curvature will be obtained if estepm is as small as stepm. */
                   5326: 
                   5327:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5328:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5329:      nhstepm is the number of hstepm from age to agelim 
                   5330:      nstepm is the number of stepm from age to agelin. 
                   5331:      Look at hpijx to understand the reason of that which relies in memory size
                   5332:      and note for a fixed period like estepm months */
                   5333:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5334:      survival function given by stepm (the optimization length). Unfortunately it
                   5335:      means that if the survival funtion is printed only each two years of age and if
                   5336:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5337:      results. So we changed our mind and took the option of the best precision.
                   5338:   */
                   5339:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5340: 
                   5341:   agelim=AGESUP;
                   5342:   /* If stepm=6 months */
                   5343:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5344:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5345:     
                   5346: /* nhstepm age range expressed in number of stepm */
                   5347:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5348:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5349:   /* if (stepm >= YEARM) hstepm=1;*/
                   5350:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5351:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5352: 
                   5353:   for (age=bage; age<=fage; age ++){ 
                   5354:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5355:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5356:     /* if (stepm >= YEARM) hstepm=1;*/
                   5357:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5358: 
                   5359:     /* If stepm=6 months */
                   5360:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5361:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5362:     
1.235     brouard  5363:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5364:     
                   5365:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5366:     
                   5367:     printf("%d|",(int)age);fflush(stdout);
                   5368:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5369:     
                   5370:     /* Computing expectancies */
                   5371:     for(i=1; i<=nlstate;i++)
                   5372:       for(j=1; j<=nlstate;j++)
                   5373:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5374:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5375:          
                   5376:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5377: 
                   5378:        }
                   5379: 
                   5380:     fprintf(ficreseij,"%3.0f",age );
                   5381:     for(i=1; i<=nlstate;i++){
                   5382:       eip=0;
                   5383:       for(j=1; j<=nlstate;j++){
                   5384:        eip +=eij[i][j][(int)age];
                   5385:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5386:       }
                   5387:       fprintf(ficreseij,"%9.4f", eip );
                   5388:     }
                   5389:     fprintf(ficreseij,"\n");
                   5390:     
                   5391:   }
                   5392:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5393:   printf("\n");
                   5394:   fprintf(ficlog,"\n");
                   5395:   
                   5396: }
                   5397: 
1.235     brouard  5398:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5399: 
                   5400: {
                   5401:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5402:      to initial status i, ei. .
1.126     brouard  5403:   */
                   5404:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5405:   int nhstepma, nstepma; /* Decreasing with age */
                   5406:   double age, agelim, hf;
                   5407:   double ***p3matp, ***p3matm, ***varhe;
                   5408:   double **dnewm,**doldm;
                   5409:   double *xp, *xm;
                   5410:   double **gp, **gm;
                   5411:   double ***gradg, ***trgradg;
                   5412:   int theta;
                   5413: 
                   5414:   double eip, vip;
                   5415: 
                   5416:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5417:   xp=vector(1,npar);
                   5418:   xm=vector(1,npar);
                   5419:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5420:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5421:   
                   5422:   pstamp(ficresstdeij);
                   5423:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5424:   fprintf(ficresstdeij,"# Age");
                   5425:   for(i=1; i<=nlstate;i++){
                   5426:     for(j=1; j<=nlstate;j++)
                   5427:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5428:     fprintf(ficresstdeij," e%1d. ",i);
                   5429:   }
                   5430:   fprintf(ficresstdeij,"\n");
                   5431: 
                   5432:   pstamp(ficrescveij);
                   5433:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5434:   fprintf(ficrescveij,"# Age");
                   5435:   for(i=1; i<=nlstate;i++)
                   5436:     for(j=1; j<=nlstate;j++){
                   5437:       cptj= (j-1)*nlstate+i;
                   5438:       for(i2=1; i2<=nlstate;i2++)
                   5439:        for(j2=1; j2<=nlstate;j2++){
                   5440:          cptj2= (j2-1)*nlstate+i2;
                   5441:          if(cptj2 <= cptj)
                   5442:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5443:        }
                   5444:     }
                   5445:   fprintf(ficrescveij,"\n");
                   5446:   
                   5447:   if(estepm < stepm){
                   5448:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5449:   }
                   5450:   else  hstepm=estepm;   
                   5451:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5452:    * This is mainly to measure the difference between two models: for example
                   5453:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5454:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5455:    * progression in between and thus overestimating or underestimating according
                   5456:    * to the curvature of the survival function. If, for the same date, we 
                   5457:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5458:    * to compare the new estimate of Life expectancy with the same linear 
                   5459:    * hypothesis. A more precise result, taking into account a more precise
                   5460:    * curvature will be obtained if estepm is as small as stepm. */
                   5461: 
                   5462:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5463:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5464:      nhstepm is the number of hstepm from age to agelim 
                   5465:      nstepm is the number of stepm from age to agelin. 
                   5466:      Look at hpijx to understand the reason of that which relies in memory size
                   5467:      and note for a fixed period like estepm months */
                   5468:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5469:      survival function given by stepm (the optimization length). Unfortunately it
                   5470:      means that if the survival funtion is printed only each two years of age and if
                   5471:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5472:      results. So we changed our mind and took the option of the best precision.
                   5473:   */
                   5474:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5475: 
                   5476:   /* If stepm=6 months */
                   5477:   /* nhstepm age range expressed in number of stepm */
                   5478:   agelim=AGESUP;
                   5479:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5480:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5481:   /* if (stepm >= YEARM) hstepm=1;*/
                   5482:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5483:   
                   5484:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5485:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5486:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5487:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5488:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5489:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5490: 
                   5491:   for (age=bage; age<=fage; age ++){ 
                   5492:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5493:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5494:     /* if (stepm >= YEARM) hstepm=1;*/
                   5495:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5496:                
1.126     brouard  5497:     /* If stepm=6 months */
                   5498:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5499:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5500:     
                   5501:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5502:                
1.126     brouard  5503:     /* Computing  Variances of health expectancies */
                   5504:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5505:        decrease memory allocation */
                   5506:     for(theta=1; theta <=npar; theta++){
                   5507:       for(i=1; i<=npar; i++){ 
1.222     brouard  5508:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5509:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5510:       }
1.235     brouard  5511:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5512:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5513:                        
1.126     brouard  5514:       for(j=1; j<= nlstate; j++){
1.222     brouard  5515:        for(i=1; i<=nlstate; i++){
                   5516:          for(h=0; h<=nhstepm-1; h++){
                   5517:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5518:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5519:          }
                   5520:        }
1.126     brouard  5521:       }
1.218     brouard  5522:                        
1.126     brouard  5523:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5524:        for(h=0; h<=nhstepm-1; h++){
                   5525:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5526:        }
1.126     brouard  5527:     }/* End theta */
                   5528:     
                   5529:     
                   5530:     for(h=0; h<=nhstepm-1; h++)
                   5531:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5532:        for(theta=1; theta <=npar; theta++)
                   5533:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5534:     
1.218     brouard  5535:                
1.222     brouard  5536:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5537:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5538:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5539:                
1.222     brouard  5540:     printf("%d|",(int)age);fflush(stdout);
                   5541:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5542:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5543:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5544:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5545:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5546:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5547:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5548:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5549:       }
                   5550:     }
1.218     brouard  5551:                
1.126     brouard  5552:     /* Computing expectancies */
1.235     brouard  5553:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5554:     for(i=1; i<=nlstate;i++)
                   5555:       for(j=1; j<=nlstate;j++)
1.222     brouard  5556:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5557:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5558:                                        
1.222     brouard  5559:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5560:                                        
1.222     brouard  5561:        }
1.218     brouard  5562:                
1.126     brouard  5563:     fprintf(ficresstdeij,"%3.0f",age );
                   5564:     for(i=1; i<=nlstate;i++){
                   5565:       eip=0.;
                   5566:       vip=0.;
                   5567:       for(j=1; j<=nlstate;j++){
1.222     brouard  5568:        eip += eij[i][j][(int)age];
                   5569:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5570:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5571:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5572:       }
                   5573:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5574:     }
                   5575:     fprintf(ficresstdeij,"\n");
1.218     brouard  5576:                
1.126     brouard  5577:     fprintf(ficrescveij,"%3.0f",age );
                   5578:     for(i=1; i<=nlstate;i++)
                   5579:       for(j=1; j<=nlstate;j++){
1.222     brouard  5580:        cptj= (j-1)*nlstate+i;
                   5581:        for(i2=1; i2<=nlstate;i2++)
                   5582:          for(j2=1; j2<=nlstate;j2++){
                   5583:            cptj2= (j2-1)*nlstate+i2;
                   5584:            if(cptj2 <= cptj)
                   5585:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5586:          }
1.126     brouard  5587:       }
                   5588:     fprintf(ficrescveij,"\n");
1.218     brouard  5589:                
1.126     brouard  5590:   }
                   5591:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5592:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5593:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5594:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5595:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5596:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5597:   printf("\n");
                   5598:   fprintf(ficlog,"\n");
1.218     brouard  5599:        
1.126     brouard  5600:   free_vector(xm,1,npar);
                   5601:   free_vector(xp,1,npar);
                   5602:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5603:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5604:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5605: }
1.218     brouard  5606:  
1.126     brouard  5607: /************ Variance ******************/
1.235     brouard  5608:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5609:  {
                   5610:    /* Variance of health expectancies */
                   5611:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5612:    /* double **newm;*/
                   5613:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5614:   
                   5615:    /* int movingaverage(); */
                   5616:    double **dnewm,**doldm;
                   5617:    double **dnewmp,**doldmp;
                   5618:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5619:    int k;
                   5620:    double *xp;
                   5621:    double **gp, **gm;  /* for var eij */
                   5622:    double ***gradg, ***trgradg; /*for var eij */
                   5623:    double **gradgp, **trgradgp; /* for var p point j */
                   5624:    double *gpp, *gmp; /* for var p point j */
                   5625:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5626:    double ***p3mat;
                   5627:    double age,agelim, hf;
                   5628:    /* double ***mobaverage; */
                   5629:    int theta;
                   5630:    char digit[4];
                   5631:    char digitp[25];
                   5632: 
                   5633:    char fileresprobmorprev[FILENAMELENGTH];
                   5634: 
                   5635:    if(popbased==1){
                   5636:      if(mobilav!=0)
                   5637:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5638:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5639:    }
                   5640:    else 
                   5641:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5642: 
1.218     brouard  5643:    /* if (mobilav!=0) { */
                   5644:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5645:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5646:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5647:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5648:    /*   } */
                   5649:    /* } */
                   5650: 
                   5651:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5652:    sprintf(digit,"%-d",ij);
                   5653:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5654:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5655:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5656:    strcat(fileresprobmorprev,fileresu);
                   5657:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5658:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5659:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5660:    }
                   5661:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5662:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5663:    pstamp(ficresprobmorprev);
                   5664:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5665:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5666:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5667:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5668:    }
                   5669:    for(j=1;j<=cptcoveff;j++) 
                   5670:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5671:    fprintf(ficresprobmorprev,"\n");
                   5672: 
1.218     brouard  5673:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5674:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5675:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5676:      for(i=1; i<=nlstate;i++)
                   5677:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5678:    }  
                   5679:    fprintf(ficresprobmorprev,"\n");
                   5680:   
                   5681:    fprintf(ficgp,"\n# Routine varevsij");
                   5682:    fprintf(ficgp,"\nunset title \n");
                   5683:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5684:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5685:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5686:    /*   } */
                   5687:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5688:    pstamp(ficresvij);
                   5689:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5690:    if(popbased==1)
                   5691:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5692:    else
                   5693:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5694:    fprintf(ficresvij,"# Age");
                   5695:    for(i=1; i<=nlstate;i++)
                   5696:      for(j=1; j<=nlstate;j++)
                   5697:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5698:    fprintf(ficresvij,"\n");
                   5699: 
                   5700:    xp=vector(1,npar);
                   5701:    dnewm=matrix(1,nlstate,1,npar);
                   5702:    doldm=matrix(1,nlstate,1,nlstate);
                   5703:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5704:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5705: 
                   5706:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5707:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5708:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5709:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5710:   
1.218     brouard  5711:    if(estepm < stepm){
                   5712:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5713:    }
                   5714:    else  hstepm=estepm;   
                   5715:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5716:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5717:       nhstepm is the number of hstepm from age to agelim 
                   5718:       nstepm is the number of stepm from age to agelim. 
                   5719:       Look at function hpijx to understand why because of memory size limitations, 
                   5720:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5721:       survival function given by stepm (the optimization length). Unfortunately it
                   5722:       means that if the survival funtion is printed every two years of age and if
                   5723:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5724:       results. So we changed our mind and took the option of the best precision.
                   5725:    */
                   5726:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5727:    agelim = AGESUP;
                   5728:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5729:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5730:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5731:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5732:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5733:      gp=matrix(0,nhstepm,1,nlstate);
                   5734:      gm=matrix(0,nhstepm,1,nlstate);
                   5735:                
                   5736:                
                   5737:      for(theta=1; theta <=npar; theta++){
                   5738:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5739:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5740:        }
                   5741:                        
1.242     brouard  5742:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5743:                        
                   5744:        if (popbased==1) {
                   5745:         if(mobilav ==0){
                   5746:           for(i=1; i<=nlstate;i++)
                   5747:             prlim[i][i]=probs[(int)age][i][ij];
                   5748:         }else{ /* mobilav */ 
                   5749:           for(i=1; i<=nlstate;i++)
                   5750:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5751:         }
                   5752:        }
                   5753:                        
1.235     brouard  5754:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5755:        for(j=1; j<= nlstate; j++){
                   5756:         for(h=0; h<=nhstepm; h++){
                   5757:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5758:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5759:         }
                   5760:        }
                   5761:        /* Next for computing probability of death (h=1 means
                   5762:          computed over hstepm matrices product = hstepm*stepm months) 
                   5763:          as a weighted average of prlim.
                   5764:        */
                   5765:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5766:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5767:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5768:        }    
                   5769:        /* end probability of death */
                   5770:                        
                   5771:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5772:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5773:                        
1.242     brouard  5774:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5775:                        
                   5776:        if (popbased==1) {
                   5777:         if(mobilav ==0){
                   5778:           for(i=1; i<=nlstate;i++)
                   5779:             prlim[i][i]=probs[(int)age][i][ij];
                   5780:         }else{ /* mobilav */ 
                   5781:           for(i=1; i<=nlstate;i++)
                   5782:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5783:         }
                   5784:        }
                   5785:                        
1.235     brouard  5786:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5787:                        
                   5788:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5789:         for(h=0; h<=nhstepm; h++){
                   5790:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5791:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5792:         }
                   5793:        }
                   5794:        /* This for computing probability of death (h=1 means
                   5795:          computed over hstepm matrices product = hstepm*stepm months) 
                   5796:          as a weighted average of prlim.
                   5797:        */
                   5798:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5799:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5800:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5801:        }    
                   5802:        /* end probability of death */
                   5803:                        
                   5804:        for(j=1; j<= nlstate; j++) /* vareij */
                   5805:         for(h=0; h<=nhstepm; h++){
                   5806:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5807:         }
                   5808:                        
                   5809:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5810:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5811:        }
                   5812:                        
                   5813:      } /* End theta */
                   5814:                
                   5815:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5816:                
                   5817:      for(h=0; h<=nhstepm; h++) /* veij */
                   5818:        for(j=1; j<=nlstate;j++)
                   5819:         for(theta=1; theta <=npar; theta++)
                   5820:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5821:                
                   5822:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5823:        for(theta=1; theta <=npar; theta++)
                   5824:         trgradgp[j][theta]=gradgp[theta][j];
                   5825:                
                   5826:                
                   5827:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5828:      for(i=1;i<=nlstate;i++)
                   5829:        for(j=1;j<=nlstate;j++)
                   5830:         vareij[i][j][(int)age] =0.;
                   5831:                
                   5832:      for(h=0;h<=nhstepm;h++){
                   5833:        for(k=0;k<=nhstepm;k++){
                   5834:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5835:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5836:         for(i=1;i<=nlstate;i++)
                   5837:           for(j=1;j<=nlstate;j++)
                   5838:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5839:        }
                   5840:      }
                   5841:                
                   5842:      /* pptj */
                   5843:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5844:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5845:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5846:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5847:         varppt[j][i]=doldmp[j][i];
                   5848:      /* end ppptj */
                   5849:      /*  x centered again */
                   5850:                
1.242     brouard  5851:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5852:                
                   5853:      if (popbased==1) {
                   5854:        if(mobilav ==0){
                   5855:         for(i=1; i<=nlstate;i++)
                   5856:           prlim[i][i]=probs[(int)age][i][ij];
                   5857:        }else{ /* mobilav */ 
                   5858:         for(i=1; i<=nlstate;i++)
                   5859:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5860:        }
                   5861:      }
                   5862:                
                   5863:      /* This for computing probability of death (h=1 means
                   5864:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5865:        as a weighted average of prlim.
                   5866:      */
1.235     brouard  5867:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5868:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5869:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5870:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5871:      }    
                   5872:      /* end probability of death */
                   5873:                
                   5874:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5875:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5876:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5877:        for(i=1; i<=nlstate;i++){
                   5878:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5879:        }
                   5880:      } 
                   5881:      fprintf(ficresprobmorprev,"\n");
                   5882:                
                   5883:      fprintf(ficresvij,"%.0f ",age );
                   5884:      for(i=1; i<=nlstate;i++)
                   5885:        for(j=1; j<=nlstate;j++){
                   5886:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5887:        }
                   5888:      fprintf(ficresvij,"\n");
                   5889:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5890:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5891:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5892:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5893:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5894:    } /* End age */
                   5895:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5896:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5897:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5898:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5899:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5900:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5901:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5902:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5903:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5904:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5905:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5906:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5907:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5908:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5909:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5910:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5911:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5912:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5913:     */
1.218     brouard  5914:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5915:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5916: 
1.218     brouard  5917:    free_vector(xp,1,npar);
                   5918:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5919:    free_matrix(dnewm,1,nlstate,1,npar);
                   5920:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5921:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5922:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5923:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5924:    fclose(ficresprobmorprev);
                   5925:    fflush(ficgp);
                   5926:    fflush(fichtm); 
                   5927:  }  /* end varevsij */
1.126     brouard  5928: 
                   5929: /************ Variance of prevlim ******************/
1.235     brouard  5930:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5931: {
1.205     brouard  5932:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5933:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5934: 
1.126     brouard  5935:   double **dnewm,**doldm;
                   5936:   int i, j, nhstepm, hstepm;
                   5937:   double *xp;
                   5938:   double *gp, *gm;
                   5939:   double **gradg, **trgradg;
1.208     brouard  5940:   double **mgm, **mgp;
1.126     brouard  5941:   double age,agelim;
                   5942:   int theta;
                   5943:   
                   5944:   pstamp(ficresvpl);
                   5945:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5946:   fprintf(ficresvpl,"# Age ");
                   5947:   if(nresult >=1)
                   5948:     fprintf(ficresvpl," Result# ");
1.126     brouard  5949:   for(i=1; i<=nlstate;i++)
                   5950:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5951:   fprintf(ficresvpl,"\n");
                   5952: 
                   5953:   xp=vector(1,npar);
                   5954:   dnewm=matrix(1,nlstate,1,npar);
                   5955:   doldm=matrix(1,nlstate,1,nlstate);
                   5956:   
                   5957:   hstepm=1*YEARM; /* Every year of age */
                   5958:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5959:   agelim = AGESUP;
                   5960:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5961:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5962:     if (stepm >= YEARM) hstepm=1;
                   5963:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5964:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5965:     mgp=matrix(1,npar,1,nlstate);
                   5966:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5967:     gp=vector(1,nlstate);
                   5968:     gm=vector(1,nlstate);
                   5969: 
                   5970:     for(theta=1; theta <=npar; theta++){
                   5971:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5972:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5973:       }
1.209     brouard  5974:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5975:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5976:       else
1.235     brouard  5977:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5978:       for(i=1;i<=nlstate;i++){
1.126     brouard  5979:        gp[i] = prlim[i][i];
1.208     brouard  5980:        mgp[theta][i] = prlim[i][i];
                   5981:       }
1.126     brouard  5982:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5983:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5984:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5985:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5986:       else
1.235     brouard  5987:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5988:       for(i=1;i<=nlstate;i++){
1.126     brouard  5989:        gm[i] = prlim[i][i];
1.208     brouard  5990:        mgm[theta][i] = prlim[i][i];
                   5991:       }
1.126     brouard  5992:       for(i=1;i<=nlstate;i++)
                   5993:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5994:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5995:     } /* End theta */
                   5996: 
                   5997:     trgradg =matrix(1,nlstate,1,npar);
                   5998: 
                   5999:     for(j=1; j<=nlstate;j++)
                   6000:       for(theta=1; theta <=npar; theta++)
                   6001:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6002:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6003:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6004:     /*   for(j=1; j<=nlstate;j++){ */
                   6005:     /*         printf(" %d ",j); */
                   6006:     /*         for(theta=1; theta <=npar; theta++) */
                   6007:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6008:     /*         printf("\n "); */
                   6009:     /*   } */
                   6010:     /* } */
                   6011:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6012:     /*   printf("\n gradg %d ",(int)age); */
                   6013:     /*   for(j=1; j<=nlstate;j++){ */
                   6014:     /*         printf("%d ",j); */
                   6015:     /*         for(theta=1; theta <=npar; theta++) */
                   6016:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6017:     /*         printf("\n "); */
                   6018:     /*   } */
                   6019:     /* } */
1.126     brouard  6020: 
                   6021:     for(i=1;i<=nlstate;i++)
                   6022:       varpl[i][(int)age] =0.;
1.209     brouard  6023:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6024:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6025:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6026:     }else{
1.126     brouard  6027:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6028:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6029:     }
1.126     brouard  6030:     for(i=1;i<=nlstate;i++)
                   6031:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6032: 
                   6033:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6034:     if(nresult >=1)
                   6035:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6036:     for(i=1; i<=nlstate;i++)
                   6037:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6038:     fprintf(ficresvpl,"\n");
                   6039:     free_vector(gp,1,nlstate);
                   6040:     free_vector(gm,1,nlstate);
1.208     brouard  6041:     free_matrix(mgm,1,npar,1,nlstate);
                   6042:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6043:     free_matrix(gradg,1,npar,1,nlstate);
                   6044:     free_matrix(trgradg,1,nlstate,1,npar);
                   6045:   } /* End age */
                   6046: 
                   6047:   free_vector(xp,1,npar);
                   6048:   free_matrix(doldm,1,nlstate,1,npar);
                   6049:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6050: 
                   6051: }
                   6052: 
                   6053: /************ Variance of one-step probabilities  ******************/
                   6054: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6055:  {
                   6056:    int i, j=0,  k1, l1, tj;
                   6057:    int k2, l2, j1,  z1;
                   6058:    int k=0, l;
                   6059:    int first=1, first1, first2;
                   6060:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6061:    double **dnewm,**doldm;
                   6062:    double *xp;
                   6063:    double *gp, *gm;
                   6064:    double **gradg, **trgradg;
                   6065:    double **mu;
                   6066:    double age, cov[NCOVMAX+1];
                   6067:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6068:    int theta;
                   6069:    char fileresprob[FILENAMELENGTH];
                   6070:    char fileresprobcov[FILENAMELENGTH];
                   6071:    char fileresprobcor[FILENAMELENGTH];
                   6072:    double ***varpij;
                   6073: 
                   6074:    strcpy(fileresprob,"PROB_"); 
                   6075:    strcat(fileresprob,fileres);
                   6076:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6077:      printf("Problem with resultfile: %s\n", fileresprob);
                   6078:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6079:    }
                   6080:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6081:    strcat(fileresprobcov,fileresu);
                   6082:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6083:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6084:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6085:    }
                   6086:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6087:    strcat(fileresprobcor,fileresu);
                   6088:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6089:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6090:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6091:    }
                   6092:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6093:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6094:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6095:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6096:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6097:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6098:    pstamp(ficresprob);
                   6099:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6100:    fprintf(ficresprob,"# Age");
                   6101:    pstamp(ficresprobcov);
                   6102:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6103:    fprintf(ficresprobcov,"# Age");
                   6104:    pstamp(ficresprobcor);
                   6105:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6106:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6107: 
                   6108: 
1.222     brouard  6109:    for(i=1; i<=nlstate;i++)
                   6110:      for(j=1; j<=(nlstate+ndeath);j++){
                   6111:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6112:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6113:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6114:      }  
                   6115:    /* fprintf(ficresprob,"\n");
                   6116:       fprintf(ficresprobcov,"\n");
                   6117:       fprintf(ficresprobcor,"\n");
                   6118:    */
                   6119:    xp=vector(1,npar);
                   6120:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6121:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6122:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6123:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6124:    first=1;
                   6125:    fprintf(ficgp,"\n# Routine varprob");
                   6126:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6127:    fprintf(fichtm,"\n");
                   6128: 
                   6129:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6130:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6131:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6132: and drawn. It helps understanding how is the covariance between two incidences.\
                   6133:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6134:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6135: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6136: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6137: standard deviations wide on each axis. <br>\
                   6138:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6139:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6140: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6141: 
1.222     brouard  6142:    cov[1]=1;
                   6143:    /* tj=cptcoveff; */
1.225     brouard  6144:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6145:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6146:    j1=0;
1.224     brouard  6147:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6148:      if  (cptcovn>0) {
                   6149:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6150:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6151:        fprintf(ficresprob, "**********\n#\n");
                   6152:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6153:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6154:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6155:                        
1.222     brouard  6156:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6157:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6158:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6159:                        
                   6160:                        
1.222     brouard  6161:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6162:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6163:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6164:                        
1.222     brouard  6165:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6166:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6167:        fprintf(ficresprobcor, "**********\n#");    
                   6168:        if(invalidvarcomb[j1]){
                   6169:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6170:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6171:         continue;
                   6172:        }
                   6173:      }
                   6174:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6175:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6176:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6177:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6178:      for (age=bage; age<=fage; age ++){ 
                   6179:        cov[2]=age;
                   6180:        if(nagesqr==1)
                   6181:         cov[3]= age*age;
                   6182:        for (k=1; k<=cptcovn;k++) {
                   6183:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6184:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6185:                                                                    * 1  1 1 1 1
                   6186:                                                                    * 2  2 1 1 1
                   6187:                                                                    * 3  1 2 1 1
                   6188:                                                                    */
                   6189:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6190:        }
                   6191:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6192:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6193:        for (k=1; k<=cptcovprod;k++)
                   6194:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6195:                        
                   6196:                        
1.222     brouard  6197:        for(theta=1; theta <=npar; theta++){
                   6198:         for(i=1; i<=npar; i++)
                   6199:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6200:                                
1.222     brouard  6201:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6202:                                
1.222     brouard  6203:         k=0;
                   6204:         for(i=1; i<= (nlstate); i++){
                   6205:           for(j=1; j<=(nlstate+ndeath);j++){
                   6206:             k=k+1;
                   6207:             gp[k]=pmmij[i][j];
                   6208:           }
                   6209:         }
1.220     brouard  6210:                                
1.222     brouard  6211:         for(i=1; i<=npar; i++)
                   6212:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6213:                                
1.222     brouard  6214:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6215:         k=0;
                   6216:         for(i=1; i<=(nlstate); i++){
                   6217:           for(j=1; j<=(nlstate+ndeath);j++){
                   6218:             k=k+1;
                   6219:             gm[k]=pmmij[i][j];
                   6220:           }
                   6221:         }
1.220     brouard  6222:                                
1.222     brouard  6223:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6224:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6225:        }
1.126     brouard  6226: 
1.222     brouard  6227:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6228:         for(theta=1; theta <=npar; theta++)
                   6229:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6230:                        
1.222     brouard  6231:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6232:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6233:                        
1.222     brouard  6234:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6235:                        
1.222     brouard  6236:        k=0;
                   6237:        for(i=1; i<=(nlstate); i++){
                   6238:         for(j=1; j<=(nlstate+ndeath);j++){
                   6239:           k=k+1;
                   6240:           mu[k][(int) age]=pmmij[i][j];
                   6241:         }
                   6242:        }
                   6243:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6244:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6245:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6246:                        
1.222     brouard  6247:        /*printf("\n%d ",(int)age);
                   6248:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6249:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6250:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6251:         }*/
1.220     brouard  6252:                        
1.222     brouard  6253:        fprintf(ficresprob,"\n%d ",(int)age);
                   6254:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6255:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6256:                        
1.222     brouard  6257:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6258:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6259:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6260:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6261:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6262:        }
                   6263:        i=0;
                   6264:        for (k=1; k<=(nlstate);k++){
                   6265:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6266:           i++;
                   6267:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6268:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6269:           for (j=1; j<=i;j++){
                   6270:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6271:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6272:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6273:           }
                   6274:         }
                   6275:        }/* end of loop for state */
                   6276:      } /* end of loop for age */
                   6277:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6278:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6279:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6280:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6281:     
                   6282:      /* Confidence intervalle of pij  */
                   6283:      /*
                   6284:        fprintf(ficgp,"\nunset parametric;unset label");
                   6285:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6286:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6287:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6288:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6289:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6290:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6291:      */
                   6292:                
                   6293:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6294:      first1=1;first2=2;
                   6295:      for (k2=1; k2<=(nlstate);k2++){
                   6296:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6297:         if(l2==k2) continue;
                   6298:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6299:         for (k1=1; k1<=(nlstate);k1++){
                   6300:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6301:             if(l1==k1) continue;
                   6302:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6303:             if(i<=j) continue;
                   6304:             for (age=bage; age<=fage; age ++){ 
                   6305:               if ((int)age %5==0){
                   6306:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6307:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6308:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6309:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6310:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6311:                 c12=cv12/sqrt(v1*v2);
                   6312:                 /* Computing eigen value of matrix of covariance */
                   6313:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6314:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6315:                 if ((lc2 <0) || (lc1 <0) ){
                   6316:                   if(first2==1){
                   6317:                     first1=0;
                   6318:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6319:                   }
                   6320:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6321:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6322:                   /* lc2=fabs(lc2); */
                   6323:                 }
1.220     brouard  6324:                                                                
1.222     brouard  6325:                 /* Eigen vectors */
                   6326:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6327:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6328:                 v21=(lc1-v1)/cv12*v11;
                   6329:                 v12=-v21;
                   6330:                 v22=v11;
                   6331:                 tnalp=v21/v11;
                   6332:                 if(first1==1){
                   6333:                   first1=0;
                   6334:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6335:                 }
                   6336:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6337:                 /*printf(fignu*/
                   6338:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6339:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6340:                 if(first==1){
                   6341:                   first=0;
                   6342:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6343:                   fprintf(ficgp,"\nset parametric;unset label");
                   6344:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6345:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6346:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6347:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6348: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6349:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6350:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6351:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6352:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6353:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6354:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6355:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6356:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6357:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6358:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6359:                 }else{
                   6360:                   first=0;
                   6361:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6362:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6363:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6364:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6365:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6366:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6367:                 }/* if first */
                   6368:               } /* age mod 5 */
                   6369:             } /* end loop age */
                   6370:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6371:             first=1;
                   6372:           } /*l12 */
                   6373:         } /* k12 */
                   6374:        } /*l1 */
                   6375:      }/* k1 */
                   6376:    }  /* loop on combination of covariates j1 */
                   6377:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6378:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6379:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6380:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6381:    free_vector(xp,1,npar);
                   6382:    fclose(ficresprob);
                   6383:    fclose(ficresprobcov);
                   6384:    fclose(ficresprobcor);
                   6385:    fflush(ficgp);
                   6386:    fflush(fichtmcov);
                   6387:  }
1.126     brouard  6388: 
                   6389: 
                   6390: /******************* Printing html file ***********/
1.201     brouard  6391: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6392:                  int lastpass, int stepm, int weightopt, char model[],\
                   6393:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6394:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6395:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6396:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6397:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6398: 
                   6399:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6400:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6401: </ul>");
1.237     brouard  6402:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6403: </ul>", model);
1.214     brouard  6404:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6405:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6406:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6407:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6408:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6409:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6410:    fprintf(fichtm,"\
                   6411:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6412:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6413:    fprintf(fichtm,"\
1.217     brouard  6414:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6415:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6416:    fprintf(fichtm,"\
1.126     brouard  6417:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6418:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6419:    fprintf(fichtm,"\
1.217     brouard  6420:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6421:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6422:    fprintf(fichtm,"\
1.211     brouard  6423:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6424:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6425:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6426:    if(prevfcast==1){
                   6427:      fprintf(fichtm,"\
                   6428:  - Prevalence projections by age and states:                           \
1.201     brouard  6429:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6430:    }
1.126     brouard  6431: 
1.222     brouard  6432:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6433: 
1.225     brouard  6434:    m=pow(2,cptcoveff);
1.222     brouard  6435:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6436: 
1.222     brouard  6437:    jj1=0;
1.237     brouard  6438: 
                   6439:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6440:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6441:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6442:        continue;
1.220     brouard  6443: 
1.222     brouard  6444:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6445:      jj1++;
                   6446:      if (cptcovn > 0) {
                   6447:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6448:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6449:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6450:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6451:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6452:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6453:        }
1.237     brouard  6454:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6455:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6456:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6457:       }
                   6458:        
1.230     brouard  6459:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6460:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6461:        if(invalidvarcomb[k1]){
                   6462:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6463:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6464:         continue;
                   6465:        }
                   6466:      }
                   6467:      /* aij, bij */
1.259     brouard  6468:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6469: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6470:      /* Pij */
1.241     brouard  6471:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6472: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6473:      /* Quasi-incidences */
                   6474:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6475:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6476:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6477: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6478: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6479:      /* Survival functions (period) in state j */
                   6480:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6481:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6482: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6483:      }
                   6484:      /* State specific survival functions (period) */
                   6485:      for(cpt=1; cpt<=nlstate;cpt++){
                   6486:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6487:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6488:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6489:      }
                   6490:      /* Period (stable) prevalence in each health state */
                   6491:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6492:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6493: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6494:      }
                   6495:      if(backcast==1){
                   6496:        /* Period (stable) back prevalence in each health state */
                   6497:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6498:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6499: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6500:        }
1.217     brouard  6501:      }
1.222     brouard  6502:      if(prevfcast==1){
                   6503:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6504:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6505:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6506: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6507:        }
                   6508:      }
1.220     brouard  6509:         
1.222     brouard  6510:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6511:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6512: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6513:      }
                   6514:      /* } /\* end i1 *\/ */
                   6515:    }/* End k1 */
                   6516:    fprintf(fichtm,"</ul>");
1.126     brouard  6517: 
1.222     brouard  6518:    fprintf(fichtm,"\
1.126     brouard  6519: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6520:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6521:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6522: But because parameters are usually highly correlated (a higher incidence of disability \
                   6523: and a higher incidence of recovery can give very close observed transition) it might \
                   6524: be very useful to look not only at linear confidence intervals estimated from the \
                   6525: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6526: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6527: covariance matrix of the one-step probabilities. \
                   6528: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6529: 
1.222     brouard  6530:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6531:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6532:    fprintf(fichtm,"\
1.126     brouard  6533:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6534:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6535: 
1.222     brouard  6536:    fprintf(fichtm,"\
1.126     brouard  6537:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6538:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6539:    fprintf(fichtm,"\
1.126     brouard  6540:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6541:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6542:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6543:    fprintf(fichtm,"\
1.126     brouard  6544:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6545:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6546:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6547:    fprintf(fichtm,"\
1.128     brouard  6548:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6549:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6550:    fprintf(fichtm,"\
1.128     brouard  6551:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6552:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6553:    fprintf(fichtm,"\
1.126     brouard  6554:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6555:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6556: 
                   6557: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6558: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6559: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6560: /*     <br>",fileres,fileres,fileres,fileres); */
                   6561: /*  else  */
                   6562: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6563:    fflush(fichtm);
                   6564:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6565: 
1.225     brouard  6566:    m=pow(2,cptcoveff);
1.222     brouard  6567:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6568: 
1.222     brouard  6569:    jj1=0;
1.237     brouard  6570: 
1.241     brouard  6571:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6572:    for(k1=1; k1<=m;k1++){
1.253     brouard  6573:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6574:        continue;
1.222     brouard  6575:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6576:      jj1++;
1.126     brouard  6577:      if (cptcovn > 0) {
                   6578:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6579:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6580:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6581:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6582:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6583:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6584:       }
                   6585: 
1.126     brouard  6586:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6587: 
1.222     brouard  6588:        if(invalidvarcomb[k1]){
                   6589:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6590:         continue;
                   6591:        }
1.126     brouard  6592:      }
                   6593:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6594:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6595: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6596: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6597:      }
                   6598:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6599: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6600: true period expectancies (those weighted with period prevalences are also\
                   6601:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6602:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6603: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6604:      /* } /\* end i1 *\/ */
                   6605:    }/* End k1 */
1.241     brouard  6606:   }/* End nres */
1.222     brouard  6607:    fprintf(fichtm,"</ul>");
                   6608:    fflush(fichtm);
1.126     brouard  6609: }
                   6610: 
                   6611: /******************* Gnuplot file **************/
1.223     brouard  6612: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6613: 
                   6614:   char dirfileres[132],optfileres[132];
1.223     brouard  6615:   char gplotcondition[132];
1.237     brouard  6616:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6617:   int lv=0, vlv=0, kl=0;
1.130     brouard  6618:   int ng=0;
1.201     brouard  6619:   int vpopbased;
1.223     brouard  6620:   int ioffset; /* variable offset for columns */
1.235     brouard  6621:   int nres=0; /* Index of resultline */
1.219     brouard  6622: 
1.126     brouard  6623: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6624: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6625: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6626: /*   } */
                   6627: 
                   6628:   /*#ifdef windows */
                   6629:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6630:   /*#endif */
1.225     brouard  6631:   m=pow(2,cptcoveff);
1.126     brouard  6632: 
1.202     brouard  6633:   /* Contribution to likelihood */
                   6634:   /* Plot the probability implied in the likelihood */
1.223     brouard  6635:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6636:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6637:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6638:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6639: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6640:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6641: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6642:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6643:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6644:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6645:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6646:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6647:   for (i=1; i<= nlstate ; i ++) {
                   6648:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6649:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6650:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6651:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6652:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6653:     }
                   6654:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6655:   }
                   6656:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6657:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6658:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6659:   fprintf(ficgp,"\nset out;unset log\n");
                   6660:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6661: 
1.126     brouard  6662:   strcpy(dirfileres,optionfilefiname);
                   6663:   strcpy(optfileres,"vpl");
1.223     brouard  6664:   /* 1eme*/
1.238     brouard  6665:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6666:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6667:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6668:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6669:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6670:          continue;
                   6671:        /* We are interested in selected combination by the resultline */
1.246     brouard  6672:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6673:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6674:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6675:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6676:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6677:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6678:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6679:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6680:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6681:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6682:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6683:        }
                   6684:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6685:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6686:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6687:        }       
1.246     brouard  6688:        /* printf("\n#\n"); */
1.238     brouard  6689:        fprintf(ficgp,"\n#\n");
                   6690:        if(invalidvarcomb[k1]){
1.260     brouard  6691:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  6692:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6693:          continue;
                   6694:        }
1.235     brouard  6695:       
1.241     brouard  6696:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6697:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.260     brouard  6698:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   6699:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   6700:       /* k1-1 error should be nres-1*/
1.238     brouard  6701:        for (i=1; i<= nlstate ; i ++) {
                   6702:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6703:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6704:        }
1.260     brouard  6705:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  6706:        for (i=1; i<= nlstate ; i ++) {
                   6707:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6708:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6709:        } 
1.260     brouard  6710:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  6711:        for (i=1; i<= nlstate ; i ++) {
                   6712:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6713:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6714:        }  
                   6715:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6716:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6717:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6718:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6719:          if(cptcoveff ==0){
1.245     brouard  6720:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6721:          }else{
                   6722:            kl=0;
                   6723:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6724:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6725:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6726:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6727:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6728:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6729:              kl++;
1.238     brouard  6730:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6731:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6732:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6733:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6734:              if(k==cptcoveff){
1.245     brouard  6735:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6736:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6737:              }else{
                   6738:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6739:                kl++;
                   6740:              }
                   6741:            } /* end covariate */
                   6742:          } /* end if no covariate */
                   6743:        } /* end if backcast */
                   6744:        fprintf(ficgp,"\nset out \n");
                   6745:       } /* nres */
1.201     brouard  6746:     } /* k1 */
                   6747:   } /* cpt */
1.235     brouard  6748: 
                   6749:   
1.126     brouard  6750:   /*2 eme*/
1.238     brouard  6751:   for (k1=1; k1<= m ; k1 ++){  
                   6752:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6753:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6754:        continue;
                   6755:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6756:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6757:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6758:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6759:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6760:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6761:        vlv= nbcode[Tvaraff[k]][lv];
                   6762:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6763:       }
1.237     brouard  6764:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6765:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6766:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6767:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6768:       }
1.211     brouard  6769:       fprintf(ficgp,"\n#\n");
1.223     brouard  6770:       if(invalidvarcomb[k1]){
                   6771:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6772:        continue;
                   6773:       }
1.219     brouard  6774:                        
1.241     brouard  6775:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6776:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6777:        if(vpopbased==0)
                   6778:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6779:        else
                   6780:          fprintf(ficgp,"\nreplot ");
                   6781:        for (i=1; i<= nlstate+1 ; i ++) {
                   6782:          k=2*i;
1.261     brouard  6783:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  6784:          for (j=1; j<= nlstate+1 ; j ++) {
                   6785:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6786:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6787:          }   
                   6788:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6789:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  6790:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6791:          for (j=1; j<= nlstate+1 ; j ++) {
                   6792:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6793:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6794:          }   
                   6795:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  6796:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6797:          for (j=1; j<= nlstate+1 ; j ++) {
                   6798:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6799:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6800:          }   
                   6801:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6802:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6803:        } /* state */
                   6804:       } /* vpopbased */
1.244     brouard  6805:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6806:     } /* end nres */
                   6807:   } /* k1 end 2 eme*/
                   6808:        
                   6809:        
                   6810:   /*3eme*/
                   6811:   for (k1=1; k1<= m ; k1 ++){
                   6812:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6813:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6814:        continue;
                   6815: 
                   6816:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  6817:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.238     brouard  6818:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6819:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6820:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6821:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6822:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6823:          vlv= nbcode[Tvaraff[k]][lv];
                   6824:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6825:        }
                   6826:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6827:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6828:        }       
                   6829:        fprintf(ficgp,"\n#\n");
                   6830:        if(invalidvarcomb[k1]){
                   6831:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6832:          continue;
                   6833:        }
                   6834:                        
                   6835:        /*       k=2+nlstate*(2*cpt-2); */
                   6836:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6837:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6838:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  6839: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  6840:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6841:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6842:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6843:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6844:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6845:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6846:                                
1.238     brouard  6847:        */
                   6848:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  6849:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  6850:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6851:                                
1.238     brouard  6852:        } 
1.261     brouard  6853:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  6854:       }
                   6855:     } /* end nres */
                   6856:   } /* end kl 3eme */
1.126     brouard  6857:   
1.223     brouard  6858:   /* 4eme */
1.201     brouard  6859:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6860:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6861:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6862:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6863:        continue;
1.238     brouard  6864:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6865:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6866:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6867:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6868:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6869:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6870:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6871:          vlv= nbcode[Tvaraff[k]][lv];
                   6872:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6873:        }
                   6874:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6875:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6876:        }       
                   6877:        fprintf(ficgp,"\n#\n");
                   6878:        if(invalidvarcomb[k1]){
                   6879:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6880:          continue;
1.223     brouard  6881:        }
1.238     brouard  6882:       
1.241     brouard  6883:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6884:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6885: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6886:        k=3;
                   6887:        for (i=1; i<= nlstate ; i ++){
                   6888:          if(i==1){
                   6889:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6890:          }else{
                   6891:            fprintf(ficgp,", '' ");
                   6892:          }
                   6893:          l=(nlstate+ndeath)*(i-1)+1;
                   6894:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6895:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6896:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6897:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6898:        } /* nlstate */
                   6899:        fprintf(ficgp,"\nset out\n");
                   6900:       } /* end cpt state*/ 
                   6901:     } /* end nres */
                   6902:   } /* end covariate k1 */  
                   6903: 
1.220     brouard  6904: /* 5eme */
1.201     brouard  6905:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6906:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6907:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6908:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6909:        continue;
1.238     brouard  6910:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6911:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6912:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6913:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6914:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6915:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6916:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6917:          vlv= nbcode[Tvaraff[k]][lv];
                   6918:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6919:        }
                   6920:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6921:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6922:        }       
                   6923:        fprintf(ficgp,"\n#\n");
                   6924:        if(invalidvarcomb[k1]){
                   6925:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6926:          continue;
                   6927:        }
1.227     brouard  6928:       
1.241     brouard  6929:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6930:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6931: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6932:        k=3;
                   6933:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6934:          if(j==1)
                   6935:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6936:          else
                   6937:            fprintf(ficgp,", '' ");
                   6938:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6939:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6940:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6941:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6942:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6943:        } /* nlstate */
                   6944:        fprintf(ficgp,", '' ");
                   6945:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6946:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6947:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6948:          if(j < nlstate)
                   6949:            fprintf(ficgp,"$%d +",k+l);
                   6950:          else
                   6951:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6952:        }
                   6953:        fprintf(ficgp,"\nset out\n");
                   6954:       } /* end cpt state*/ 
                   6955:     } /* end covariate */  
                   6956:   } /* end nres */
1.227     brouard  6957:   
1.220     brouard  6958: /* 6eme */
1.202     brouard  6959:   /* CV preval stable (period) for each covariate */
1.237     brouard  6960:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6961:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6962:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6963:       continue;
1.255     brouard  6964:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6965:       
1.211     brouard  6966:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6967:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6968:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6969:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6970:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6971:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6972:        vlv= nbcode[Tvaraff[k]][lv];
                   6973:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6974:       }
1.237     brouard  6975:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6976:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6977:       }        
1.211     brouard  6978:       fprintf(ficgp,"\n#\n");
1.223     brouard  6979:       if(invalidvarcomb[k1]){
1.227     brouard  6980:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6981:        continue;
1.223     brouard  6982:       }
1.227     brouard  6983:       
1.241     brouard  6984:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6985:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6986: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6987:       k=3; /* Offset */
1.255     brouard  6988:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6989:        if(i==1)
                   6990:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6991:        else
                   6992:          fprintf(ficgp,", '' ");
1.255     brouard  6993:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6994:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6995:        for (j=2; j<= nlstate ; j ++)
                   6996:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6997:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6998:       } /* nlstate */
1.201     brouard  6999:       fprintf(ficgp,"\nset out\n");
1.153     brouard  7000:     } /* end cpt state*/ 
                   7001:   } /* end covariate */  
1.227     brouard  7002:   
                   7003:   
1.220     brouard  7004: /* 7eme */
1.218     brouard  7005:   if(backcast == 1){
1.217     brouard  7006:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7007:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7008:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7009:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7010:        continue;
1.255     brouard  7011:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   7012:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7013:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7014:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7015:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7016:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7017:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7018:          vlv= nbcode[Tvaraff[k]][lv];
                   7019:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7020:        }
1.237     brouard  7021:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7022:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7023:        }       
1.227     brouard  7024:        fprintf(ficgp,"\n#\n");
                   7025:        if(invalidvarcomb[k1]){
                   7026:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7027:          continue;
                   7028:        }
                   7029:        
1.241     brouard  7030:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7031:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7032: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7033:        k=3; /* Offset */
1.255     brouard  7034:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7035:          if(i==1)
                   7036:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7037:          else
                   7038:            fprintf(ficgp,", '' ");
                   7039:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7040:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7041:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7042:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7043:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7044:          /* for (j=2; j<= nlstate ; j ++) */
                   7045:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7046:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7047:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7048:        } /* nlstate */
                   7049:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7050:       } /* end cpt state*/ 
                   7051:     } /* end covariate */  
                   7052:   } /* End if backcast */
                   7053:   
1.223     brouard  7054:   /* 8eme */
1.218     brouard  7055:   if(prevfcast==1){
                   7056:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7057:     
1.237     brouard  7058:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7059:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7060:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7061:        continue;
1.211     brouard  7062:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7063:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7064:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7065:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7066:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7067:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7068:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7069:          vlv= nbcode[Tvaraff[k]][lv];
                   7070:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7071:        }
1.237     brouard  7072:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7073:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7074:        }       
1.227     brouard  7075:        fprintf(ficgp,"\n#\n");
                   7076:        if(invalidvarcomb[k1]){
                   7077:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7078:          continue;
                   7079:        }
                   7080:        
                   7081:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7082:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7083:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7084: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7085:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7086:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7087:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7088:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7089:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7090:          if(i==1){
                   7091:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7092:          }else{
                   7093:            fprintf(ficgp,",\\\n '' ");
                   7094:          }
                   7095:          if(cptcoveff ==0){ /* No covariate */
                   7096:            ioffset=2; /* Age is in 2 */
                   7097:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7098:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7099:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7100:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7101:            fprintf(ficgp," u %d:(", ioffset); 
                   7102:            if(i==nlstate+1)
                   7103:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7104:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7105:            else
                   7106:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7107:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7108:          }else{ /* more than 2 covariates */
                   7109:            if(cptcoveff ==1){
                   7110:              ioffset=4; /* Age is in 4 */
                   7111:            }else{
                   7112:              ioffset=6; /* Age is in 6 */
                   7113:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7114:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7115:            }   
                   7116:            fprintf(ficgp," u %d:(",ioffset); 
                   7117:            kl=0;
                   7118:            strcpy(gplotcondition,"(");
                   7119:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7120:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7121:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7122:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7123:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7124:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7125:              kl++;
                   7126:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7127:              kl++;
                   7128:              if(k <cptcoveff && cptcoveff>1)
                   7129:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7130:            }
                   7131:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7132:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7133:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7134:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7135:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7136:            if(i==nlstate+1){
                   7137:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7138:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7139:            }else{
                   7140:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7141:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7142:            }
                   7143:          } /* end if covariate */
                   7144:        } /* nlstate */
                   7145:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7146:       } /* end cpt state*/
                   7147:     } /* end covariate */
                   7148:   } /* End if prevfcast */
1.227     brouard  7149:   
                   7150:   
1.238     brouard  7151:   /* 9eme writing MLE parameters */
                   7152:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7153:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7154:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7155:     for(k=1; k <=(nlstate+ndeath); k++){
                   7156:       if (k != i) {
1.227     brouard  7157:        fprintf(ficgp,"#   current state %d\n",k);
                   7158:        for(j=1; j <=ncovmodel; j++){
                   7159:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7160:          jk++; 
                   7161:        }
                   7162:        fprintf(ficgp,"\n");
1.126     brouard  7163:       }
                   7164:     }
1.223     brouard  7165:   }
1.187     brouard  7166:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7167:   
1.145     brouard  7168:   /*goto avoid;*/
1.238     brouard  7169:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7170:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7171:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7172:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7173:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7174:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7175:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7176:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7177:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7178:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7179:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7180:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7181:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7182:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7183:   fprintf(ficgp,"#\n");
1.223     brouard  7184:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7185:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7186:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7187:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7188:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7189:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7190:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7191:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7192:        continue;
                   7193:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7194:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7195:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7196:       }        
                   7197:       fprintf(ficgp,"\n#\n");
1.241     brouard  7198:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7199:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7200:       if (ng==1){
                   7201:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7202:        fprintf(ficgp,"\nunset log y");
                   7203:       }else if (ng==2){
                   7204:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7205:        fprintf(ficgp,"\nset log y");
                   7206:       }else if (ng==3){
                   7207:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7208:        fprintf(ficgp,"\nset log y");
                   7209:       }else
                   7210:        fprintf(ficgp,"\nunset title ");
                   7211:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7212:       i=1;
                   7213:       for(k2=1; k2<=nlstate; k2++) {
                   7214:        k3=i;
                   7215:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7216:          if (k != k2){
                   7217:            switch( ng) {
                   7218:            case 1:
                   7219:              if(nagesqr==0)
                   7220:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7221:              else /* nagesqr =1 */
                   7222:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7223:              break;
                   7224:            case 2: /* ng=2 */
                   7225:              if(nagesqr==0)
                   7226:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7227:              else /* nagesqr =1 */
                   7228:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7229:              break;
                   7230:            case 3:
                   7231:              if(nagesqr==0)
                   7232:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7233:              else /* nagesqr =1 */
                   7234:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7235:              break;
                   7236:            }
                   7237:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7238:            ijp=1; /* product no age */
                   7239:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7240:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7241:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7242:              if(j==Tage[ij]) { /* Product by age */
                   7243:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7244:                  if(DummyV[j]==0){
1.237     brouard  7245:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7246:                  }else{ /* quantitative */
                   7247:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7248:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7249:                  }
                   7250:                  ij++;
                   7251:                }
                   7252:              }else if(j==Tprod[ijp]) { /* */ 
                   7253:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7254:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7255:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7256:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7257:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7258:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7259:                    }else{ /* Vn is dummy and Vm is quanti */
                   7260:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7261:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7262:                    }
                   7263:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7264:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7265:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7266:                    }else{ /* Both quanti */
                   7267:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7268:                    }
                   7269:                  }
1.238     brouard  7270:                  ijp++;
1.237     brouard  7271:                }
                   7272:              } else{  /* simple covariate */
                   7273:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7274:                if(Dummy[j]==0){
                   7275:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7276:                }else{ /* quantitative */
                   7277:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7278:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7279:                }
1.237     brouard  7280:              } /* end simple */
                   7281:            } /* end j */
1.223     brouard  7282:          }else{
                   7283:            i=i-ncovmodel;
                   7284:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7285:              fprintf(ficgp," (1.");
                   7286:          }
1.227     brouard  7287:          
1.223     brouard  7288:          if(ng != 1){
                   7289:            fprintf(ficgp,")/(1");
1.227     brouard  7290:            
1.223     brouard  7291:            for(k1=1; k1 <=nlstate; k1++){ 
                   7292:              if(nagesqr==0)
                   7293:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7294:              else /* nagesqr =1 */
                   7295:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7296:               
1.223     brouard  7297:              ij=1;
                   7298:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7299:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7300:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7301:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7302:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7303:                    ij++;
                   7304:                  }
                   7305:                }
                   7306:                else
1.225     brouard  7307:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7308:              }
                   7309:              fprintf(ficgp,")");
                   7310:            }
                   7311:            fprintf(ficgp,")");
                   7312:            if(ng ==2)
                   7313:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7314:            else /* ng= 3 */
                   7315:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7316:          }else{ /* end ng <> 1 */
                   7317:            if( k !=k2) /* logit p11 is hard to draw */
                   7318:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7319:          }
                   7320:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7321:            fprintf(ficgp,",");
                   7322:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7323:            fprintf(ficgp,",");
                   7324:          i=i+ncovmodel;
                   7325:        } /* end k */
                   7326:       } /* end k2 */
                   7327:       fprintf(ficgp,"\n set out\n");
                   7328:     } /* end jk */
                   7329:   } /* end ng */
                   7330:   /* avoid: */
                   7331:   fflush(ficgp); 
1.126     brouard  7332: }  /* end gnuplot */
                   7333: 
                   7334: 
                   7335: /*************** Moving average **************/
1.219     brouard  7336: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7337:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7338:    
1.222     brouard  7339:    int i, cpt, cptcod;
                   7340:    int modcovmax =1;
                   7341:    int mobilavrange, mob;
                   7342:    int iage=0;
                   7343: 
                   7344:    double sum=0.;
                   7345:    double age;
                   7346:    double *sumnewp, *sumnewm;
                   7347:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7348:   
                   7349:   
1.225     brouard  7350:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7351:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7352: 
                   7353:    sumnewp = vector(1,ncovcombmax);
                   7354:    sumnewm = vector(1,ncovcombmax);
                   7355:    agemingood = vector(1,ncovcombmax); 
                   7356:    agemaxgood = vector(1,ncovcombmax);
                   7357: 
                   7358:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7359:      sumnewm[cptcod]=0.;
                   7360:      sumnewp[cptcod]=0.;
                   7361:      agemingood[cptcod]=0;
                   7362:      agemaxgood[cptcod]=0;
                   7363:    }
                   7364:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7365:   
                   7366:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7367:      if(mobilav==1) mobilavrange=5; /* default */
                   7368:      else mobilavrange=mobilav;
                   7369:      for (age=bage; age<=fage; age++)
                   7370:        for (i=1; i<=nlstate;i++)
                   7371:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7372:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7373:      /* We keep the original values on the extreme ages bage, fage and for 
                   7374:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7375:        we use a 5 terms etc. until the borders are no more concerned. 
                   7376:      */ 
                   7377:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7378:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7379:         for (i=1; i<=nlstate;i++){
                   7380:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7381:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7382:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7383:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7384:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7385:             }
                   7386:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7387:           }
                   7388:         }
                   7389:        }/* end age */
                   7390:      }/* end mob */
                   7391:    }else
                   7392:      return -1;
                   7393:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7394:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7395:      if(invalidvarcomb[cptcod]){
                   7396:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7397:        continue;
                   7398:      }
1.219     brouard  7399: 
1.222     brouard  7400:      agemingood[cptcod]=fage-(mob-1)/2;
                   7401:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7402:        sumnewm[cptcod]=0.;
                   7403:        for (i=1; i<=nlstate;i++){
                   7404:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7405:        }
                   7406:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7407:         agemingood[cptcod]=age;
                   7408:        }else{ /* bad */
                   7409:         for (i=1; i<=nlstate;i++){
                   7410:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7411:         } /* i */
                   7412:        } /* end bad */
                   7413:      }/* age */
                   7414:      sum=0.;
                   7415:      for (i=1; i<=nlstate;i++){
                   7416:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7417:      }
                   7418:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7419:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7420:        /* for (i=1; i<=nlstate;i++){ */
                   7421:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7422:        /* } /\* i *\/ */
                   7423:      } /* end bad */
                   7424:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7425:      /* From youngest, finding the oldest wrong */
                   7426:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7427:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7428:        sumnewm[cptcod]=0.;
                   7429:        for (i=1; i<=nlstate;i++){
                   7430:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7431:        }
                   7432:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7433:         agemaxgood[cptcod]=age;
                   7434:        }else{ /* bad */
                   7435:         for (i=1; i<=nlstate;i++){
                   7436:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7437:         } /* i */
                   7438:        } /* end bad */
                   7439:      }/* age */
                   7440:      sum=0.;
                   7441:      for (i=1; i<=nlstate;i++){
                   7442:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7443:      }
                   7444:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7445:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7446:        /* for (i=1; i<=nlstate;i++){ */
                   7447:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7448:        /* } /\* i *\/ */
                   7449:      } /* end bad */
                   7450:                
                   7451:      for (age=bage; age<=fage; age++){
1.235     brouard  7452:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7453:        sumnewp[cptcod]=0.;
                   7454:        sumnewm[cptcod]=0.;
                   7455:        for (i=1; i<=nlstate;i++){
                   7456:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7457:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7458:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7459:        }
                   7460:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7461:      }
                   7462:      /* printf("\n"); */
                   7463:      /* } */
                   7464:      /* brutal averaging */
                   7465:      for (i=1; i<=nlstate;i++){
                   7466:        for (age=1; age<=bage; age++){
                   7467:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7468:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7469:        }       
                   7470:        for (age=fage; age<=AGESUP; age++){
                   7471:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7472:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7473:        }
                   7474:      } /* end i status */
                   7475:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7476:        for (age=1; age<=AGESUP; age++){
                   7477:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7478:         mobaverage[(int)age][i][cptcod]=0.;
                   7479:        }
                   7480:      }
                   7481:    }/* end cptcod */
                   7482:    free_vector(sumnewm,1, ncovcombmax);
                   7483:    free_vector(sumnewp,1, ncovcombmax);
                   7484:    free_vector(agemaxgood,1, ncovcombmax);
                   7485:    free_vector(agemingood,1, ncovcombmax);
                   7486:    return 0;
                   7487:  }/* End movingaverage */
1.218     brouard  7488:  
1.126     brouard  7489: 
                   7490: /************** Forecasting ******************/
1.235     brouard  7491:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7492:   /* proj1, year, month, day of starting projection 
                   7493:      agemin, agemax range of age
                   7494:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7495:      anproj2 year of en of projection (same day and month as proj1).
                   7496:   */
1.235     brouard  7497:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7498:   double agec; /* generic age */
                   7499:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7500:   double *popeffectif,*popcount;
                   7501:   double ***p3mat;
1.218     brouard  7502:   /* double ***mobaverage; */
1.126     brouard  7503:   char fileresf[FILENAMELENGTH];
                   7504: 
                   7505:   agelim=AGESUP;
1.211     brouard  7506:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7507:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7508:      We still use firstpass and lastpass as another selection.
                   7509:   */
1.214     brouard  7510:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7511:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7512:  
1.201     brouard  7513:   strcpy(fileresf,"F_"); 
                   7514:   strcat(fileresf,fileresu);
1.126     brouard  7515:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7516:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7517:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7518:   }
1.235     brouard  7519:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7520:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7521: 
1.225     brouard  7522:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7523: 
                   7524: 
                   7525:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7526:   if (stepm<=12) stepsize=1;
                   7527:   if(estepm < stepm){
                   7528:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7529:   }
                   7530:   else  hstepm=estepm;   
                   7531: 
                   7532:   hstepm=hstepm/stepm; 
                   7533:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7534:                                fractional in yp1 */
                   7535:   anprojmean=yp;
                   7536:   yp2=modf((yp1*12),&yp);
                   7537:   mprojmean=yp;
                   7538:   yp1=modf((yp2*30.5),&yp);
                   7539:   jprojmean=yp;
                   7540:   if(jprojmean==0) jprojmean=1;
                   7541:   if(mprojmean==0) jprojmean=1;
                   7542: 
1.227     brouard  7543:   i1=pow(2,cptcoveff);
1.126     brouard  7544:   if (cptcovn < 1){i1=1;}
                   7545:   
                   7546:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7547:   
                   7548:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7549:   
1.126     brouard  7550: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7551:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7552:   for(k=1; k<=i1;k++){
1.253     brouard  7553:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7554:       continue;
1.227     brouard  7555:     if(invalidvarcomb[k]){
                   7556:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7557:       continue;
                   7558:     }
                   7559:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7560:     for(j=1;j<=cptcoveff;j++) {
                   7561:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7562:     }
1.235     brouard  7563:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7564:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7565:     }
1.227     brouard  7566:     fprintf(ficresf," yearproj age");
                   7567:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7568:       for(i=1; i<=nlstate;i++)               
                   7569:        fprintf(ficresf," p%d%d",i,j);
                   7570:       fprintf(ficresf," wp.%d",j);
                   7571:     }
                   7572:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7573:       fprintf(ficresf,"\n");
                   7574:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7575:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7576:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7577:        nhstepm = nhstepm/hstepm; 
                   7578:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7579:        oldm=oldms;savm=savms;
1.235     brouard  7580:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7581:        
                   7582:        for (h=0; h<=nhstepm; h++){
                   7583:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7584:            fprintf(ficresf,"\n");
                   7585:            for(j=1;j<=cptcoveff;j++) 
                   7586:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7587:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7588:          } 
                   7589:          for(j=1; j<=nlstate+ndeath;j++) {
                   7590:            ppij=0.;
                   7591:            for(i=1; i<=nlstate;i++) {
                   7592:              if (mobilav==1) 
                   7593:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7594:              else {
                   7595:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7596:              }
                   7597:              if (h*hstepm/YEARM*stepm== yearp) {
                   7598:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7599:              }
                   7600:            } /* end i */
                   7601:            if (h*hstepm/YEARM*stepm==yearp) {
                   7602:              fprintf(ficresf," %.3f", ppij);
                   7603:            }
                   7604:          }/* end j */
                   7605:        } /* end h */
                   7606:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7607:       } /* end agec */
                   7608:     } /* end yearp */
                   7609:   } /* end  k */
1.219     brouard  7610:        
1.126     brouard  7611:   fclose(ficresf);
1.215     brouard  7612:   printf("End of Computing forecasting \n");
                   7613:   fprintf(ficlog,"End of Computing forecasting\n");
                   7614: 
1.126     brouard  7615: }
                   7616: 
1.218     brouard  7617: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7618: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7619: /*   /\* back1, year, month, day of starting backection  */
                   7620: /*      agemin, agemax range of age */
                   7621: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7622: /*      anback2 year of en of backection (same day and month as back1). */
                   7623: /*   *\/ */
                   7624: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7625: /*   double agec; /\* generic age *\/ */
                   7626: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7627: /*   double *popeffectif,*popcount; */
                   7628: /*   double ***p3mat; */
                   7629: /*   /\* double ***mobaverage; *\/ */
                   7630: /*   char fileresfb[FILENAMELENGTH]; */
                   7631:        
                   7632: /*   agelim=AGESUP; */
                   7633: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7634: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7635: /*      We still use firstpass and lastpass as another selection. */
                   7636: /*   *\/ */
                   7637: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7638: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7639: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7640:        
                   7641: /*   strcpy(fileresfb,"FB_");  */
                   7642: /*   strcat(fileresfb,fileresu); */
                   7643: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7644: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7645: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7646: /*   } */
                   7647: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7648: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7649:        
1.225     brouard  7650: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7651:        
                   7652: /*   /\* if (mobilav!=0) { *\/ */
                   7653: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7654: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7655: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7656: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7657: /*   /\*   } *\/ */
                   7658: /*   /\* } *\/ */
                   7659:        
                   7660: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7661: /*   if (stepm<=12) stepsize=1; */
                   7662: /*   if(estepm < stepm){ */
                   7663: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7664: /*   } */
                   7665: /*   else  hstepm=estepm;    */
                   7666:        
                   7667: /*   hstepm=hstepm/stepm;  */
                   7668: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7669: /*                                fractional in yp1 *\/ */
                   7670: /*   anprojmean=yp; */
                   7671: /*   yp2=modf((yp1*12),&yp); */
                   7672: /*   mprojmean=yp; */
                   7673: /*   yp1=modf((yp2*30.5),&yp); */
                   7674: /*   jprojmean=yp; */
                   7675: /*   if(jprojmean==0) jprojmean=1; */
                   7676: /*   if(mprojmean==0) jprojmean=1; */
                   7677:        
1.225     brouard  7678: /*   i1=cptcoveff; */
1.218     brouard  7679: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7680:   
1.218     brouard  7681: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7682:   
1.218     brouard  7683: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7684:        
                   7685: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7686: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7687: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7688: /*       k=k+1; */
                   7689: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7690: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7691: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7692: /*       } */
                   7693: /*       fprintf(ficresfb," yearbproj age"); */
                   7694: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7695: /*                             for(i=1; i<=nlstate;i++)               */
                   7696: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7697: /*                             fprintf(ficresfb," p.%d",j); */
                   7698: /*       } */
                   7699: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7700: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7701: /*                             fprintf(ficresfb,"\n"); */
                   7702: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7703: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7704: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7705: /*                                     nhstepm = nhstepm/hstepm;  */
                   7706: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7707: /*                                     oldm=oldms;savm=savms; */
                   7708: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7709: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7710: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7711: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7712: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7713: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7714: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7715: /*                                             }  */
                   7716: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7717: /*                                                     ppij=0.; */
                   7718: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7719: /*                                                             if (mobilav==1)  */
                   7720: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7721: /*                                                             else { */
                   7722: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7723: /*                                                             } */
                   7724: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7725: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7726: /*                                                             } */
                   7727: /*                                                     } /\* end i *\/ */
                   7728: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7729: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7730: /*                                                     } */
                   7731: /*                                             }/\* end j *\/ */
                   7732: /*                                     } /\* end h *\/ */
                   7733: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7734: /*                             } /\* end agec *\/ */
                   7735: /*       } /\* end yearp *\/ */
                   7736: /*     } /\* end cptcod *\/ */
                   7737: /*   } /\* end  cptcov *\/ */
                   7738:        
                   7739: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7740:        
                   7741: /*   fclose(ficresfb); */
                   7742: /*   printf("End of Computing Back forecasting \n"); */
                   7743: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7744:        
1.218     brouard  7745: /* } */
1.217     brouard  7746: 
1.126     brouard  7747: /************** Forecasting *****not tested NB*************/
1.227     brouard  7748: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7749:   
1.227     brouard  7750: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7751: /*   int *popage; */
                   7752: /*   double calagedatem, agelim, kk1, kk2; */
                   7753: /*   double *popeffectif,*popcount; */
                   7754: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7755: /*   /\* double ***mobaverage; *\/ */
                   7756: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7757: 
1.227     brouard  7758: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7759: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7760: /*   agelim=AGESUP; */
                   7761: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7762:   
1.227     brouard  7763: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7764:   
                   7765:   
1.227     brouard  7766: /*   strcpy(filerespop,"POP_");  */
                   7767: /*   strcat(filerespop,fileresu); */
                   7768: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7769: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7770: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7771: /*   } */
                   7772: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7773: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7774: 
1.227     brouard  7775: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7776: 
1.227     brouard  7777: /*   /\* if (mobilav!=0) { *\/ */
                   7778: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7779: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7780: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7781: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7782: /*   /\*   } *\/ */
                   7783: /*   /\* } *\/ */
1.126     brouard  7784: 
1.227     brouard  7785: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7786: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7787:   
1.227     brouard  7788: /*   agelim=AGESUP; */
1.126     brouard  7789:   
1.227     brouard  7790: /*   hstepm=1; */
                   7791: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7792:        
1.227     brouard  7793: /*   if (popforecast==1) { */
                   7794: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7795: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7796: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7797: /*     }  */
                   7798: /*     popage=ivector(0,AGESUP); */
                   7799: /*     popeffectif=vector(0,AGESUP); */
                   7800: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7801:     
1.227     brouard  7802: /*     i=1;    */
                   7803: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7804:     
1.227     brouard  7805: /*     imx=i; */
                   7806: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7807: /*   } */
1.218     brouard  7808:   
1.227     brouard  7809: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7810: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7811: /*       k=k+1; */
                   7812: /*       fprintf(ficrespop,"\n#******"); */
                   7813: /*       for(j=1;j<=cptcoveff;j++) { */
                   7814: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7815: /*       } */
                   7816: /*       fprintf(ficrespop,"******\n"); */
                   7817: /*       fprintf(ficrespop,"# Age"); */
                   7818: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7819: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7820:       
1.227     brouard  7821: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7822: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7823:        
1.227     brouard  7824: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7825: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7826: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7827:          
1.227     brouard  7828: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7829: /*       oldm=oldms;savm=savms; */
                   7830: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7831:          
1.227     brouard  7832: /*       for (h=0; h<=nhstepm; h++){ */
                   7833: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7834: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7835: /*         }  */
                   7836: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7837: /*           kk1=0.;kk2=0; */
                   7838: /*           for(i=1; i<=nlstate;i++) {               */
                   7839: /*             if (mobilav==1)  */
                   7840: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7841: /*             else { */
                   7842: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7843: /*             } */
                   7844: /*           } */
                   7845: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7846: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7847: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7848: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7849: /*           } */
                   7850: /*         } */
                   7851: /*         for(i=1; i<=nlstate;i++){ */
                   7852: /*           kk1=0.; */
                   7853: /*           for(j=1; j<=nlstate;j++){ */
                   7854: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7855: /*           } */
                   7856: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7857: /*         } */
1.218     brouard  7858:            
1.227     brouard  7859: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7860: /*           for(j=1; j<=nlstate;j++)  */
                   7861: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7862: /*       } */
                   7863: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7864: /*     } */
                   7865: /*       } */
1.218     brouard  7866:       
1.227     brouard  7867: /*       /\******\/ */
1.218     brouard  7868:       
1.227     brouard  7869: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7870: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7871: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7872: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7873: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7874:          
1.227     brouard  7875: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7876: /*       oldm=oldms;savm=savms; */
                   7877: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7878: /*       for (h=0; h<=nhstepm; h++){ */
                   7879: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7880: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7881: /*         }  */
                   7882: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7883: /*           kk1=0.;kk2=0; */
                   7884: /*           for(i=1; i<=nlstate;i++) {               */
                   7885: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7886: /*           } */
                   7887: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7888: /*         } */
                   7889: /*       } */
                   7890: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7891: /*     } */
                   7892: /*       } */
                   7893: /*     }  */
                   7894: /*   } */
1.218     brouard  7895:   
1.227     brouard  7896: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7897:   
1.227     brouard  7898: /*   if (popforecast==1) { */
                   7899: /*     free_ivector(popage,0,AGESUP); */
                   7900: /*     free_vector(popeffectif,0,AGESUP); */
                   7901: /*     free_vector(popcount,0,AGESUP); */
                   7902: /*   } */
                   7903: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7904: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7905: /*   fclose(ficrespop); */
                   7906: /* } /\* End of popforecast *\/ */
1.218     brouard  7907:  
1.126     brouard  7908: int fileappend(FILE *fichier, char *optionfich)
                   7909: {
                   7910:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7911:     printf("Problem with file: %s\n", optionfich);
                   7912:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7913:     return (0);
                   7914:   }
                   7915:   fflush(fichier);
                   7916:   return (1);
                   7917: }
                   7918: 
                   7919: 
                   7920: /**************** function prwizard **********************/
                   7921: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7922: {
                   7923: 
                   7924:   /* Wizard to print covariance matrix template */
                   7925: 
1.164     brouard  7926:   char ca[32], cb[32];
                   7927:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7928:   int numlinepar;
                   7929: 
                   7930:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7931:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7932:   for(i=1; i <=nlstate; i++){
                   7933:     jj=0;
                   7934:     for(j=1; j <=nlstate+ndeath; j++){
                   7935:       if(j==i) continue;
                   7936:       jj++;
                   7937:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7938:       printf("%1d%1d",i,j);
                   7939:       fprintf(ficparo,"%1d%1d",i,j);
                   7940:       for(k=1; k<=ncovmodel;k++){
                   7941:        /*        printf(" %lf",param[i][j][k]); */
                   7942:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7943:        printf(" 0.");
                   7944:        fprintf(ficparo," 0.");
                   7945:       }
                   7946:       printf("\n");
                   7947:       fprintf(ficparo,"\n");
                   7948:     }
                   7949:   }
                   7950:   printf("# Scales (for hessian or gradient estimation)\n");
                   7951:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7952:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7953:   for(i=1; i <=nlstate; i++){
                   7954:     jj=0;
                   7955:     for(j=1; j <=nlstate+ndeath; j++){
                   7956:       if(j==i) continue;
                   7957:       jj++;
                   7958:       fprintf(ficparo,"%1d%1d",i,j);
                   7959:       printf("%1d%1d",i,j);
                   7960:       fflush(stdout);
                   7961:       for(k=1; k<=ncovmodel;k++){
                   7962:        /*      printf(" %le",delti3[i][j][k]); */
                   7963:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7964:        printf(" 0.");
                   7965:        fprintf(ficparo," 0.");
                   7966:       }
                   7967:       numlinepar++;
                   7968:       printf("\n");
                   7969:       fprintf(ficparo,"\n");
                   7970:     }
                   7971:   }
                   7972:   printf("# Covariance matrix\n");
                   7973: /* # 121 Var(a12)\n\ */
                   7974: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7975: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7976: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7977: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7978: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7979: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7980: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7981:   fflush(stdout);
                   7982:   fprintf(ficparo,"# Covariance matrix\n");
                   7983:   /* # 121 Var(a12)\n\ */
                   7984:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7985:   /* #   ...\n\ */
                   7986:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7987:   
                   7988:   for(itimes=1;itimes<=2;itimes++){
                   7989:     jj=0;
                   7990:     for(i=1; i <=nlstate; i++){
                   7991:       for(j=1; j <=nlstate+ndeath; j++){
                   7992:        if(j==i) continue;
                   7993:        for(k=1; k<=ncovmodel;k++){
                   7994:          jj++;
                   7995:          ca[0]= k+'a'-1;ca[1]='\0';
                   7996:          if(itimes==1){
                   7997:            printf("#%1d%1d%d",i,j,k);
                   7998:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7999:          }else{
                   8000:            printf("%1d%1d%d",i,j,k);
                   8001:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8002:            /*  printf(" %.5le",matcov[i][j]); */
                   8003:          }
                   8004:          ll=0;
                   8005:          for(li=1;li <=nlstate; li++){
                   8006:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8007:              if(lj==li) continue;
                   8008:              for(lk=1;lk<=ncovmodel;lk++){
                   8009:                ll++;
                   8010:                if(ll<=jj){
                   8011:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8012:                  if(ll<jj){
                   8013:                    if(itimes==1){
                   8014:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8015:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8016:                    }else{
                   8017:                      printf(" 0.");
                   8018:                      fprintf(ficparo," 0.");
                   8019:                    }
                   8020:                  }else{
                   8021:                    if(itimes==1){
                   8022:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8023:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8024:                    }else{
                   8025:                      printf(" 0.");
                   8026:                      fprintf(ficparo," 0.");
                   8027:                    }
                   8028:                  }
                   8029:                }
                   8030:              } /* end lk */
                   8031:            } /* end lj */
                   8032:          } /* end li */
                   8033:          printf("\n");
                   8034:          fprintf(ficparo,"\n");
                   8035:          numlinepar++;
                   8036:        } /* end k*/
                   8037:       } /*end j */
                   8038:     } /* end i */
                   8039:   } /* end itimes */
                   8040: 
                   8041: } /* end of prwizard */
                   8042: /******************* Gompertz Likelihood ******************************/
                   8043: double gompertz(double x[])
                   8044: { 
                   8045:   double A,B,L=0.0,sump=0.,num=0.;
                   8046:   int i,n=0; /* n is the size of the sample */
                   8047: 
1.220     brouard  8048:   for (i=1;i<=imx ; i++) {
1.126     brouard  8049:     sump=sump+weight[i];
                   8050:     /*    sump=sump+1;*/
                   8051:     num=num+1;
                   8052:   }
                   8053:  
                   8054:  
                   8055:   /* for (i=0; i<=imx; i++) 
                   8056:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8057: 
                   8058:   for (i=1;i<=imx ; i++)
                   8059:     {
                   8060:       if (cens[i] == 1 && wav[i]>1)
                   8061:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8062:       
                   8063:       if (cens[i] == 0 && wav[i]>1)
                   8064:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8065:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8066:       
                   8067:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8068:       if (wav[i] > 1 ) { /* ??? */
                   8069:        L=L+A*weight[i];
                   8070:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8071:       }
                   8072:     }
                   8073: 
                   8074:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8075:  
                   8076:   return -2*L*num/sump;
                   8077: }
                   8078: 
1.136     brouard  8079: #ifdef GSL
                   8080: /******************* Gompertz_f Likelihood ******************************/
                   8081: double gompertz_f(const gsl_vector *v, void *params)
                   8082: { 
                   8083:   double A,B,LL=0.0,sump=0.,num=0.;
                   8084:   double *x= (double *) v->data;
                   8085:   int i,n=0; /* n is the size of the sample */
                   8086: 
                   8087:   for (i=0;i<=imx-1 ; i++) {
                   8088:     sump=sump+weight[i];
                   8089:     /*    sump=sump+1;*/
                   8090:     num=num+1;
                   8091:   }
                   8092:  
                   8093:  
                   8094:   /* for (i=0; i<=imx; i++) 
                   8095:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8096:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8097:   for (i=1;i<=imx ; i++)
                   8098:     {
                   8099:       if (cens[i] == 1 && wav[i]>1)
                   8100:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8101:       
                   8102:       if (cens[i] == 0 && wav[i]>1)
                   8103:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8104:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8105:       
                   8106:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8107:       if (wav[i] > 1 ) { /* ??? */
                   8108:        LL=LL+A*weight[i];
                   8109:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8110:       }
                   8111:     }
                   8112: 
                   8113:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8114:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8115:  
                   8116:   return -2*LL*num/sump;
                   8117: }
                   8118: #endif
                   8119: 
1.126     brouard  8120: /******************* Printing html file ***********/
1.201     brouard  8121: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8122:                  int lastpass, int stepm, int weightopt, char model[],\
                   8123:                  int imx,  double p[],double **matcov,double agemortsup){
                   8124:   int i,k;
                   8125: 
                   8126:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8127:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8128:   for (i=1;i<=2;i++) 
                   8129:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8130:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8131:   fprintf(fichtm,"</ul>");
                   8132: 
                   8133: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8134: 
                   8135:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8136: 
                   8137:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8138:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8139: 
                   8140:  
                   8141:   fflush(fichtm);
                   8142: }
                   8143: 
                   8144: /******************* Gnuplot file **************/
1.201     brouard  8145: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8146: 
                   8147:   char dirfileres[132],optfileres[132];
1.164     brouard  8148: 
1.126     brouard  8149:   int ng;
                   8150: 
                   8151: 
                   8152:   /*#ifdef windows */
                   8153:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8154:     /*#endif */
                   8155: 
                   8156: 
                   8157:   strcpy(dirfileres,optionfilefiname);
                   8158:   strcpy(optfileres,"vpl");
1.199     brouard  8159:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8160:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8161:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8162:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8163:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8164: 
                   8165: } 
                   8166: 
1.136     brouard  8167: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8168: {
1.126     brouard  8169: 
1.136     brouard  8170:   /*-------- data file ----------*/
                   8171:   FILE *fic;
                   8172:   char dummy[]="                         ";
1.240     brouard  8173:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8174:   int lstra;
1.136     brouard  8175:   int linei, month, year,iout;
                   8176:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8177:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8178:   char *stratrunc;
1.223     brouard  8179: 
1.240     brouard  8180:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8181:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8182: 
1.240     brouard  8183:   for(v=1; v <=ncovcol;v++){
                   8184:     DummyV[v]=0;
                   8185:     FixedV[v]=0;
                   8186:   }
                   8187:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8188:     DummyV[v]=1;
                   8189:     FixedV[v]=0;
                   8190:   }
                   8191:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8192:     DummyV[v]=0;
                   8193:     FixedV[v]=1;
                   8194:   }
                   8195:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8196:     DummyV[v]=1;
                   8197:     FixedV[v]=1;
                   8198:   }
                   8199:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8200:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8201:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8202:   }
1.126     brouard  8203: 
1.136     brouard  8204:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8205:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8206:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8207:   }
1.126     brouard  8208: 
1.136     brouard  8209:   i=1;
                   8210:   linei=0;
                   8211:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8212:     linei=linei+1;
                   8213:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8214:       if(line[j] == '\t')
                   8215:        line[j] = ' ';
                   8216:     }
                   8217:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8218:       ;
                   8219:     };
                   8220:     line[j+1]=0;  /* Trims blanks at end of line */
                   8221:     if(line[0]=='#'){
                   8222:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8223:       printf("Comment line\n%s\n",line);
                   8224:       continue;
                   8225:     }
                   8226:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8227:     strcpy(line, linetmp);
1.223     brouard  8228:     
                   8229:     /* Loops on waves */
                   8230:     for (j=maxwav;j>=1;j--){
                   8231:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8232:        cutv(stra, strb, line, ' '); 
                   8233:        if(strb[0]=='.') { /* Missing value */
                   8234:          lval=-1;
                   8235:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8236:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8237:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8238:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8239:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8240:            return 1;
                   8241:          }
                   8242:        }else{
                   8243:          errno=0;
                   8244:          /* what_kind_of_number(strb); */
                   8245:          dval=strtod(strb,&endptr); 
                   8246:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8247:          /* if(strb != endptr && *endptr == '\0') */
                   8248:          /*    dval=dlval; */
                   8249:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8250:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8251:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8252:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8253:            return 1;
                   8254:          }
                   8255:          cotqvar[j][iv][i]=dval; 
                   8256:          cotvar[j][ntv+iv][i]=dval; 
                   8257:        }
                   8258:        strcpy(line,stra);
1.223     brouard  8259:       }/* end loop ntqv */
1.225     brouard  8260:       
1.223     brouard  8261:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8262:        cutv(stra, strb, line, ' '); 
                   8263:        if(strb[0]=='.') { /* Missing value */
                   8264:          lval=-1;
                   8265:        }else{
                   8266:          errno=0;
                   8267:          lval=strtol(strb,&endptr,10); 
                   8268:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8269:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8270:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8271:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8272:            return 1;
                   8273:          }
                   8274:        }
                   8275:        if(lval <-1 || lval >1){
                   8276:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8277:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8278:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8279:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8280:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8281:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8282:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8283:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8284:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8285:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8286:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8287:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8288:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8289:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8290:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8291:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8292:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8293:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8294:          return 1;
                   8295:        }
                   8296:        cotvar[j][iv][i]=(double)(lval);
                   8297:        strcpy(line,stra);
1.223     brouard  8298:       }/* end loop ntv */
1.225     brouard  8299:       
1.223     brouard  8300:       /* Statuses  at wave */
1.137     brouard  8301:       cutv(stra, strb, line, ' '); 
1.223     brouard  8302:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8303:        lval=-1;
1.136     brouard  8304:       }else{
1.238     brouard  8305:        errno=0;
                   8306:        lval=strtol(strb,&endptr,10); 
                   8307:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8308:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8309:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8310:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8311:          return 1;
                   8312:        }
1.136     brouard  8313:       }
1.225     brouard  8314:       
1.136     brouard  8315:       s[j][i]=lval;
1.225     brouard  8316:       
1.223     brouard  8317:       /* Date of Interview */
1.136     brouard  8318:       strcpy(line,stra);
                   8319:       cutv(stra, strb,line,' ');
1.169     brouard  8320:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8321:       }
1.169     brouard  8322:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8323:        month=99;
                   8324:        year=9999;
1.136     brouard  8325:       }else{
1.225     brouard  8326:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8327:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8328:        return 1;
1.136     brouard  8329:       }
                   8330:       anint[j][i]= (double) year; 
                   8331:       mint[j][i]= (double)month; 
                   8332:       strcpy(line,stra);
1.223     brouard  8333:     } /* End loop on waves */
1.225     brouard  8334:     
1.223     brouard  8335:     /* Date of death */
1.136     brouard  8336:     cutv(stra, strb,line,' '); 
1.169     brouard  8337:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8338:     }
1.169     brouard  8339:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8340:       month=99;
                   8341:       year=9999;
                   8342:     }else{
1.141     brouard  8343:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8344:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8345:       return 1;
1.136     brouard  8346:     }
                   8347:     andc[i]=(double) year; 
                   8348:     moisdc[i]=(double) month; 
                   8349:     strcpy(line,stra);
                   8350:     
1.223     brouard  8351:     /* Date of birth */
1.136     brouard  8352:     cutv(stra, strb,line,' '); 
1.169     brouard  8353:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8354:     }
1.169     brouard  8355:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8356:       month=99;
                   8357:       year=9999;
                   8358:     }else{
1.141     brouard  8359:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8360:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8361:       return 1;
1.136     brouard  8362:     }
                   8363:     if (year==9999) {
1.141     brouard  8364:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8365:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8366:       return 1;
                   8367:       
1.136     brouard  8368:     }
                   8369:     annais[i]=(double)(year);
                   8370:     moisnais[i]=(double)(month); 
                   8371:     strcpy(line,stra);
1.225     brouard  8372:     
1.223     brouard  8373:     /* Sample weight */
1.136     brouard  8374:     cutv(stra, strb,line,' '); 
                   8375:     errno=0;
                   8376:     dval=strtod(strb,&endptr); 
                   8377:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8378:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8379:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8380:       fflush(ficlog);
                   8381:       return 1;
                   8382:     }
                   8383:     weight[i]=dval; 
                   8384:     strcpy(line,stra);
1.225     brouard  8385:     
1.223     brouard  8386:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8387:       cutv(stra, strb, line, ' '); 
                   8388:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8389:        lval=-1;
1.223     brouard  8390:       }else{
1.225     brouard  8391:        errno=0;
                   8392:        /* what_kind_of_number(strb); */
                   8393:        dval=strtod(strb,&endptr);
                   8394:        /* if(strb != endptr && *endptr == '\0') */
                   8395:        /*   dval=dlval; */
                   8396:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8397:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8398:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8399:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8400:          return 1;
                   8401:        }
                   8402:        coqvar[iv][i]=dval; 
1.226     brouard  8403:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8404:       }
                   8405:       strcpy(line,stra);
                   8406:     }/* end loop nqv */
1.136     brouard  8407:     
1.223     brouard  8408:     /* Covariate values */
1.136     brouard  8409:     for (j=ncovcol;j>=1;j--){
                   8410:       cutv(stra, strb,line,' '); 
1.223     brouard  8411:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8412:        lval=-1;
1.136     brouard  8413:       }else{
1.225     brouard  8414:        errno=0;
                   8415:        lval=strtol(strb,&endptr,10); 
                   8416:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8417:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8418:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8419:          return 1;
                   8420:        }
1.136     brouard  8421:       }
                   8422:       if(lval <-1 || lval >1){
1.225     brouard  8423:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8424:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8425:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8426:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8427:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8428:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8429:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8430:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8431:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8432:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8433:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8434:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8435:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8436:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8437:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8438:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8439:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8440:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8441:        return 1;
1.136     brouard  8442:       }
                   8443:       covar[j][i]=(double)(lval);
                   8444:       strcpy(line,stra);
                   8445:     }  
                   8446:     lstra=strlen(stra);
1.225     brouard  8447:     
1.136     brouard  8448:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8449:       stratrunc = &(stra[lstra-9]);
                   8450:       num[i]=atol(stratrunc);
                   8451:     }
                   8452:     else
                   8453:       num[i]=atol(stra);
                   8454:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8455:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8456:     
                   8457:     i=i+1;
                   8458:   } /* End loop reading  data */
1.225     brouard  8459:   
1.136     brouard  8460:   *imax=i-1; /* Number of individuals */
                   8461:   fclose(fic);
1.225     brouard  8462:   
1.136     brouard  8463:   return (0);
1.164     brouard  8464:   /* endread: */
1.225     brouard  8465:   printf("Exiting readdata: ");
                   8466:   fclose(fic);
                   8467:   return (1);
1.223     brouard  8468: }
1.126     brouard  8469: 
1.234     brouard  8470: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8471:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8472:   while (*p2 == ' ')
1.234     brouard  8473:     p2++; 
                   8474:   /* while ((*p1++ = *p2++) !=0) */
                   8475:   /*   ; */
                   8476:   /* do */
                   8477:   /*   while (*p2 == ' ') */
                   8478:   /*     p2++; */
                   8479:   /* while (*p1++ == *p2++); */
                   8480:   *stri=p2; 
1.145     brouard  8481: }
                   8482: 
1.235     brouard  8483: int decoderesult ( char resultline[], int nres)
1.230     brouard  8484: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8485: {
1.235     brouard  8486:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8487:   char resultsav[MAXLINE];
1.234     brouard  8488:   int resultmodel[MAXLINE];
                   8489:   int modelresult[MAXLINE];
1.230     brouard  8490:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8491: 
1.234     brouard  8492:   removefirstspace(&resultline);
1.233     brouard  8493:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8494: 
                   8495:   if (strstr(resultline,"v") !=0){
                   8496:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8497:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8498:     return 1;
                   8499:   }
                   8500:   trimbb(resultsav, resultline);
                   8501:   if (strlen(resultsav) >1){
                   8502:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8503:   }
1.253     brouard  8504:   if(j == 0){ /* Resultline but no = */
                   8505:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8506:     return (0);
                   8507:   }
                   8508:     
1.234     brouard  8509:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8510:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8511:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8512:   }
                   8513:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8514:     if(nbocc(resultsav,'=') >1){
                   8515:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8516:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8517:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8518:     }else
                   8519:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8520:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8521:     
1.230     brouard  8522:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8523:     Tvarsel[k]=atoi(strc);
                   8524:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8525:     /* cptcovsel++;     */
                   8526:     if (nbocc(stra,'=') >0)
                   8527:       strcpy(resultsav,stra); /* and analyzes it */
                   8528:   }
1.235     brouard  8529:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8530:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8531:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8532:       match=0;
1.236     brouard  8533:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8534:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8535:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8536:          match=1;
                   8537:          break;
                   8538:        }
                   8539:       }
                   8540:       if(match == 0){
                   8541:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8542:       }
                   8543:     }
                   8544:   }
1.235     brouard  8545:   /* Checking for missing or useless values in comparison of current model needs */
                   8546:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8547:     match=0;
1.235     brouard  8548:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8549:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8550:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8551:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8552:          ++match;
                   8553:        }
                   8554:       }
                   8555:     }
                   8556:     if(match == 0){
                   8557:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8558:     }else if(match > 1){
                   8559:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8560:     }
                   8561:   }
1.235     brouard  8562:       
1.234     brouard  8563:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8564:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8565:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8566:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8567:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8568:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8569:   /*    1 0 0 0 */
                   8570:   /*    2 1 0 0 */
                   8571:   /*    3 0 1 0 */ 
                   8572:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8573:   /*    5 0 0 1 */
                   8574:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8575:   /*    7 0 1 1 */
                   8576:   /*    8 1 1 1 */
1.237     brouard  8577:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8578:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8579:   /* V5*age V5 known which value for nres?  */
                   8580:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8581:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8582:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8583:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8584:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8585:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8586:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8587:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8588:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8589:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8590:       k4++;;
                   8591:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8592:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8593:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8594:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8595:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8596:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8597:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8598:       k4q++;;
                   8599:     }
                   8600:   }
1.234     brouard  8601:   
1.235     brouard  8602:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8603:   return (0);
                   8604: }
1.235     brouard  8605: 
1.230     brouard  8606: int decodemodel( char model[], int lastobs)
                   8607:  /**< This routine decodes the model and returns:
1.224     brouard  8608:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8609:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8610:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8611:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8612:        * - cptcovage number of covariates with age*products =2
                   8613:        * - cptcovs number of simple covariates
                   8614:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8615:        *     which is a new column after the 9 (ncovcol) variables. 
                   8616:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8617:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8618:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8619:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8620:        */
1.136     brouard  8621: {
1.238     brouard  8622:   int i, j, k, ks, v;
1.227     brouard  8623:   int  j1, k1, k2, k3, k4;
1.136     brouard  8624:   char modelsav[80];
1.145     brouard  8625:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8626:   char *strpt;
1.136     brouard  8627: 
1.145     brouard  8628:   /*removespace(model);*/
1.136     brouard  8629:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8630:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8631:     if (strstr(model,"AGE") !=0){
1.192     brouard  8632:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8633:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8634:       return 1;
                   8635:     }
1.141     brouard  8636:     if (strstr(model,"v") !=0){
                   8637:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8638:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8639:       return 1;
                   8640:     }
1.187     brouard  8641:     strcpy(modelsav,model); 
                   8642:     if ((strpt=strstr(model,"age*age")) !=0){
                   8643:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8644:       if(strpt != model){
1.234     brouard  8645:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8646:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8647:  corresponding column of parameters.\n",model);
1.234     brouard  8648:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8649:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8650:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8651:        return 1;
1.225     brouard  8652:       }
1.187     brouard  8653:       nagesqr=1;
                   8654:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8655:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8656:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8657:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8658:       else 
1.234     brouard  8659:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8660:     }else
                   8661:       nagesqr=0;
                   8662:     if (strlen(modelsav) >1){
                   8663:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8664:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8665:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8666:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8667:                     * cst, age and age*age 
                   8668:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8669:       /* including age products which are counted in cptcovage.
                   8670:        * but the covariates which are products must be treated 
                   8671:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8672:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8673:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8674:       
                   8675:       
1.187     brouard  8676:       /*   Design
                   8677:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8678:        *  <          ncovcol=8                >
                   8679:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8680:        *   k=  1    2      3       4     5       6      7        8
                   8681:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8682:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8683:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8684:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8685:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8686:        *  Tage[++cptcovage]=k
                   8687:        *       if products, new covar are created after ncovcol with k1
                   8688:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8689:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8690:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8691:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8692:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8693:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8694:        *  <          ncovcol=8                >
                   8695:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8696:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8697:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8698:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8699:        * p Tprod[1]@2={                         6, 5}
                   8700:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8701:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8702:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8703:        *How to reorganize?
                   8704:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8705:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8706:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8707:        * Struct []
                   8708:        */
1.225     brouard  8709:       
1.187     brouard  8710:       /* This loop fills the array Tvar from the string 'model'.*/
                   8711:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8712:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8713:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8714:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8715:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8716:       /*       k=1 Tvar[1]=2 (from V2) */
                   8717:       /*       k=5 Tvar[5] */
                   8718:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8719:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8720:       /*       } */
1.198     brouard  8721:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8722:       /*
                   8723:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8724:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8725:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8726:       }
1.187     brouard  8727:       cptcovage=0;
                   8728:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8729:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8730:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8731:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8732:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8733:        /*scanf("%d",i);*/
                   8734:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8735:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8736:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8737:            /* covar is not filled and then is empty */
                   8738:            cptcovprod--;
                   8739:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8740:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8741:            Typevar[k]=1;  /* 1 for age product */
                   8742:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8743:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8744:            /*printf("stre=%s ", stre);*/
                   8745:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8746:            cptcovprod--;
                   8747:            cutl(stre,strb,strc,'V');
                   8748:            Tvar[k]=atoi(stre);
                   8749:            Typevar[k]=1;  /* 1 for age product */
                   8750:            cptcovage++;
                   8751:            Tage[cptcovage]=k;
                   8752:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8753:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8754:            cptcovn++;
                   8755:            cptcovprodnoage++;k1++;
                   8756:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8757:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8758:                                                because this model-covariate is a construction we invent a new column
                   8759:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8760:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8761:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8762:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8763:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8764:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8765:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8766:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8767:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8768:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8769:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8770:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8771:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8772:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8773:            for (i=1; i<=lastobs;i++){
                   8774:              /* Computes the new covariate which is a product of
                   8775:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8776:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8777:            }
                   8778:          } /* End age is not in the model */
                   8779:        } /* End if model includes a product */
                   8780:        else { /* no more sum */
                   8781:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8782:          /*  scanf("%d",i);*/
                   8783:          cutl(strd,strc,strb,'V');
                   8784:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8785:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8786:          Tvar[k]=atoi(strd);
                   8787:          Typevar[k]=0;  /* 0 for simple covariates */
                   8788:        }
                   8789:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8790:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8791:                                  scanf("%d",i);*/
1.187     brouard  8792:       } /* end of loop + on total covariates */
                   8793:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8794:   } /* end if strlen(model == 0) */
1.136     brouard  8795:   
                   8796:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8797:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8798:   
1.136     brouard  8799:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8800:      printf("cptcovprod=%d ", cptcovprod);
                   8801:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8802:      scanf("%d ",i);*/
                   8803: 
                   8804: 
1.230     brouard  8805: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8806:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8807: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8808:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8809:    k =           1    2   3     4       5       6      7      8        9
                   8810:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8811:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8812:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8813:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8814:          Tmodelind[combination of covar]=k;
1.225     brouard  8815: */  
                   8816: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8817:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8818:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8819:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8820:   printf("Model=%s\n\
                   8821: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8822: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8823: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8824:   fprintf(ficlog,"Model=%s\n\
                   8825: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8826: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8827: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8828:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8829:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8830:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8831:       Fixed[k]= 0;
                   8832:       Dummy[k]= 0;
1.225     brouard  8833:       ncoveff++;
1.232     brouard  8834:       ncovf++;
1.234     brouard  8835:       nsd++;
                   8836:       modell[k].maintype= FTYPE;
                   8837:       TvarsD[nsd]=Tvar[k];
                   8838:       TvarsDind[nsd]=k;
                   8839:       TvarF[ncovf]=Tvar[k];
                   8840:       TvarFind[ncovf]=k;
                   8841:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8842:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8843:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8844:       Fixed[k]= 0;
                   8845:       Dummy[k]= 0;
                   8846:       ncoveff++;
                   8847:       ncovf++;
                   8848:       modell[k].maintype= FTYPE;
                   8849:       TvarF[ncovf]=Tvar[k];
                   8850:       TvarFind[ncovf]=k;
1.230     brouard  8851:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8852:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8853:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8854:       Fixed[k]= 0;
                   8855:       Dummy[k]= 1;
1.230     brouard  8856:       nqfveff++;
1.234     brouard  8857:       modell[k].maintype= FTYPE;
                   8858:       modell[k].subtype= FQ;
                   8859:       nsq++;
                   8860:       TvarsQ[nsq]=Tvar[k];
                   8861:       TvarsQind[nsq]=k;
1.232     brouard  8862:       ncovf++;
1.234     brouard  8863:       TvarF[ncovf]=Tvar[k];
                   8864:       TvarFind[ncovf]=k;
1.231     brouard  8865:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8866:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8867:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8868:       Fixed[k]= 1;
                   8869:       Dummy[k]= 0;
1.225     brouard  8870:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8871:       modell[k].maintype= VTYPE;
                   8872:       modell[k].subtype= VD;
                   8873:       nsd++;
                   8874:       TvarsD[nsd]=Tvar[k];
                   8875:       TvarsDind[nsd]=k;
                   8876:       ncovv++; /* Only simple time varying variables */
                   8877:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8878:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8879:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8880:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8881:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8882:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8883:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8884:       Fixed[k]= 1;
                   8885:       Dummy[k]= 1;
                   8886:       nqtveff++;
                   8887:       modell[k].maintype= VTYPE;
                   8888:       modell[k].subtype= VQ;
                   8889:       ncovv++; /* Only simple time varying variables */
                   8890:       nsq++;
                   8891:       TvarsQ[nsq]=Tvar[k];
                   8892:       TvarsQind[nsq]=k;
                   8893:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8894:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8895:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8896:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8897:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8898:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8899:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8900:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8901:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8902:       ncova++;
                   8903:       TvarA[ncova]=Tvar[k];
                   8904:       TvarAind[ncova]=k;
1.231     brouard  8905:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8906:        Fixed[k]= 2;
                   8907:        Dummy[k]= 2;
                   8908:        modell[k].maintype= ATYPE;
                   8909:        modell[k].subtype= APFD;
                   8910:        /* ncoveff++; */
1.227     brouard  8911:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8912:        Fixed[k]= 2;
                   8913:        Dummy[k]= 3;
                   8914:        modell[k].maintype= ATYPE;
                   8915:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8916:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8917:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8918:        Fixed[k]= 3;
                   8919:        Dummy[k]= 2;
                   8920:        modell[k].maintype= ATYPE;
                   8921:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8922:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8923:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8924:        Fixed[k]= 3;
                   8925:        Dummy[k]= 3;
                   8926:        modell[k].maintype= ATYPE;
                   8927:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8928:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8929:       }
                   8930:     }else if (Typevar[k] == 2) {  /* product without age */
                   8931:       k1=Tposprod[k];
                   8932:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8933:        if(Tvard[k1][2] <=ncovcol){
                   8934:          Fixed[k]= 1;
                   8935:          Dummy[k]= 0;
                   8936:          modell[k].maintype= FTYPE;
                   8937:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8938:          ncovf++; /* Fixed variables without age */
                   8939:          TvarF[ncovf]=Tvar[k];
                   8940:          TvarFind[ncovf]=k;
                   8941:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8942:          Fixed[k]= 0;  /* or 2 ?*/
                   8943:          Dummy[k]= 1;
                   8944:          modell[k].maintype= FTYPE;
                   8945:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8946:          ncovf++; /* Varying variables without age */
                   8947:          TvarF[ncovf]=Tvar[k];
                   8948:          TvarFind[ncovf]=k;
                   8949:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8950:          Fixed[k]= 1;
                   8951:          Dummy[k]= 0;
                   8952:          modell[k].maintype= VTYPE;
                   8953:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8954:          ncovv++; /* Varying variables without age */
                   8955:          TvarV[ncovv]=Tvar[k];
                   8956:          TvarVind[ncovv]=k;
                   8957:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8958:          Fixed[k]= 1;
                   8959:          Dummy[k]= 1;
                   8960:          modell[k].maintype= VTYPE;
                   8961:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8962:          ncovv++; /* Varying variables without age */
                   8963:          TvarV[ncovv]=Tvar[k];
                   8964:          TvarVind[ncovv]=k;
                   8965:        }
1.227     brouard  8966:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8967:        if(Tvard[k1][2] <=ncovcol){
                   8968:          Fixed[k]= 0;  /* or 2 ?*/
                   8969:          Dummy[k]= 1;
                   8970:          modell[k].maintype= FTYPE;
                   8971:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8972:          ncovf++; /* Fixed variables without age */
                   8973:          TvarF[ncovf]=Tvar[k];
                   8974:          TvarFind[ncovf]=k;
                   8975:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8976:          Fixed[k]= 1;
                   8977:          Dummy[k]= 1;
                   8978:          modell[k].maintype= VTYPE;
                   8979:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8980:          ncovv++; /* Varying variables without age */
                   8981:          TvarV[ncovv]=Tvar[k];
                   8982:          TvarVind[ncovv]=k;
                   8983:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8984:          Fixed[k]= 1;
                   8985:          Dummy[k]= 1;
                   8986:          modell[k].maintype= VTYPE;
                   8987:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8988:          ncovv++; /* Varying variables without age */
                   8989:          TvarV[ncovv]=Tvar[k];
                   8990:          TvarVind[ncovv]=k;
                   8991:          ncovv++; /* Varying variables without age */
                   8992:          TvarV[ncovv]=Tvar[k];
                   8993:          TvarVind[ncovv]=k;
                   8994:        }
1.227     brouard  8995:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8996:        if(Tvard[k1][2] <=ncovcol){
                   8997:          Fixed[k]= 1;
                   8998:          Dummy[k]= 1;
                   8999:          modell[k].maintype= VTYPE;
                   9000:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9001:          ncovv++; /* Varying variables without age */
                   9002:          TvarV[ncovv]=Tvar[k];
                   9003:          TvarVind[ncovv]=k;
                   9004:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9005:          Fixed[k]= 1;
                   9006:          Dummy[k]= 1;
                   9007:          modell[k].maintype= VTYPE;
                   9008:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9009:          ncovv++; /* Varying variables without age */
                   9010:          TvarV[ncovv]=Tvar[k];
                   9011:          TvarVind[ncovv]=k;
                   9012:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9013:          Fixed[k]= 1;
                   9014:          Dummy[k]= 0;
                   9015:          modell[k].maintype= VTYPE;
                   9016:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9017:          ncovv++; /* Varying variables without age */
                   9018:          TvarV[ncovv]=Tvar[k];
                   9019:          TvarVind[ncovv]=k;
                   9020:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9021:          Fixed[k]= 1;
                   9022:          Dummy[k]= 1;
                   9023:          modell[k].maintype= VTYPE;
                   9024:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9025:          ncovv++; /* Varying variables without age */
                   9026:          TvarV[ncovv]=Tvar[k];
                   9027:          TvarVind[ncovv]=k;
                   9028:        }
1.227     brouard  9029:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9030:        if(Tvard[k1][2] <=ncovcol){
                   9031:          Fixed[k]= 1;
                   9032:          Dummy[k]= 1;
                   9033:          modell[k].maintype= VTYPE;
                   9034:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9035:          ncovv++; /* Varying variables without age */
                   9036:          TvarV[ncovv]=Tvar[k];
                   9037:          TvarVind[ncovv]=k;
                   9038:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9039:          Fixed[k]= 1;
                   9040:          Dummy[k]= 1;
                   9041:          modell[k].maintype= VTYPE;
                   9042:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9043:          ncovv++; /* Varying variables without age */
                   9044:          TvarV[ncovv]=Tvar[k];
                   9045:          TvarVind[ncovv]=k;
                   9046:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9047:          Fixed[k]= 1;
                   9048:          Dummy[k]= 1;
                   9049:          modell[k].maintype= VTYPE;
                   9050:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9051:          ncovv++; /* Varying variables without age */
                   9052:          TvarV[ncovv]=Tvar[k];
                   9053:          TvarVind[ncovv]=k;
                   9054:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9055:          Fixed[k]= 1;
                   9056:          Dummy[k]= 1;
                   9057:          modell[k].maintype= VTYPE;
                   9058:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9059:          ncovv++; /* Varying variables without age */
                   9060:          TvarV[ncovv]=Tvar[k];
                   9061:          TvarVind[ncovv]=k;
                   9062:        }
1.227     brouard  9063:       }else{
1.240     brouard  9064:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9065:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9066:       } /*end k1*/
1.225     brouard  9067:     }else{
1.226     brouard  9068:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9069:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9070:     }
1.227     brouard  9071:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9072:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9073:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9074:   }
                   9075:   /* Searching for doublons in the model */
                   9076:   for(k1=1; k1<= cptcovt;k1++){
                   9077:     for(k2=1; k2 <k1;k2++){
                   9078:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9079:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9080:          if(Tvar[k1]==Tvar[k2]){
                   9081:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9082:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9083:            return(1);
                   9084:          }
                   9085:        }else if (Typevar[k1] ==2){
                   9086:          k3=Tposprod[k1];
                   9087:          k4=Tposprod[k2];
                   9088:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9089:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9090:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9091:            return(1);
                   9092:          }
                   9093:        }
1.227     brouard  9094:       }
                   9095:     }
1.225     brouard  9096:   }
                   9097:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9098:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9099:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9100:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9101:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9102:   /*endread:*/
1.225     brouard  9103:   printf("Exiting decodemodel: ");
                   9104:   return (1);
1.136     brouard  9105: }
                   9106: 
1.169     brouard  9107: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9108: {/* Check ages at death */
1.136     brouard  9109:   int i, m;
1.218     brouard  9110:   int firstone=0;
                   9111:   
1.136     brouard  9112:   for (i=1; i<=imx; i++) {
                   9113:     for(m=2; (m<= maxwav); m++) {
                   9114:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9115:        anint[m][i]=9999;
1.216     brouard  9116:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9117:          s[m][i]=-1;
1.136     brouard  9118:       }
                   9119:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9120:        *nberr = *nberr + 1;
1.218     brouard  9121:        if(firstone == 0){
                   9122:          firstone=1;
1.260     brouard  9123:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9124:        }
1.262   ! brouard  9125:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9126:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9127:       }
                   9128:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9129:        (*nberr)++;
1.259     brouard  9130:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262   ! brouard  9131:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9132:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9133:       }
                   9134:     }
                   9135:   }
                   9136: 
                   9137:   for (i=1; i<=imx; i++)  {
                   9138:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9139:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9140:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9141:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9142:          if(agedc[i]>0){
                   9143:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9144:              agev[m][i]=agedc[i];
1.214     brouard  9145:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9146:            }else {
1.136     brouard  9147:              if ((int)andc[i]!=9999){
                   9148:                nbwarn++;
                   9149:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9150:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9151:                agev[m][i]=-1;
                   9152:              }
                   9153:            }
1.169     brouard  9154:          } /* agedc > 0 */
1.214     brouard  9155:        } /* end if */
1.136     brouard  9156:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9157:                                 years but with the precision of a month */
                   9158:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9159:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9160:            agev[m][i]=1;
                   9161:          else if(agev[m][i] < *agemin){ 
                   9162:            *agemin=agev[m][i];
                   9163:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9164:          }
                   9165:          else if(agev[m][i] >*agemax){
                   9166:            *agemax=agev[m][i];
1.156     brouard  9167:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9168:          }
                   9169:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9170:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9171:        } /* en if 9*/
1.136     brouard  9172:        else { /* =9 */
1.214     brouard  9173:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9174:          agev[m][i]=1;
                   9175:          s[m][i]=-1;
                   9176:        }
                   9177:       }
1.214     brouard  9178:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9179:        agev[m][i]=1;
1.214     brouard  9180:       else{
                   9181:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9182:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9183:        agev[m][i]=0;
                   9184:       }
                   9185:     } /* End for lastpass */
                   9186:   }
1.136     brouard  9187:     
                   9188:   for (i=1; i<=imx; i++)  {
                   9189:     for(m=firstpass; (m<=lastpass); m++){
                   9190:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9191:        (*nberr)++;
1.136     brouard  9192:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9193:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9194:        return 1;
                   9195:       }
                   9196:     }
                   9197:   }
                   9198: 
                   9199:   /*for (i=1; i<=imx; i++){
                   9200:   for (m=firstpass; (m<lastpass); m++){
                   9201:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9202: }
                   9203: 
                   9204: }*/
                   9205: 
                   9206: 
1.139     brouard  9207:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9208:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9209: 
                   9210:   return (0);
1.164     brouard  9211:  /* endread:*/
1.136     brouard  9212:     printf("Exiting calandcheckages: ");
                   9213:     return (1);
                   9214: }
                   9215: 
1.172     brouard  9216: #if defined(_MSC_VER)
                   9217: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9218: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9219: //#include "stdafx.h"
                   9220: //#include <stdio.h>
                   9221: //#include <tchar.h>
                   9222: //#include <windows.h>
                   9223: //#include <iostream>
                   9224: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9225: 
                   9226: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9227: 
                   9228: BOOL IsWow64()
                   9229: {
                   9230:        BOOL bIsWow64 = FALSE;
                   9231: 
                   9232:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9233:        //  (HANDLE, PBOOL);
                   9234: 
                   9235:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9236: 
                   9237:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9238:        const char funcName[] = "IsWow64Process";
                   9239:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9240:                GetProcAddress(module, funcName);
                   9241: 
                   9242:        if (NULL != fnIsWow64Process)
                   9243:        {
                   9244:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9245:                        &bIsWow64))
                   9246:                        //throw std::exception("Unknown error");
                   9247:                        printf("Unknown error\n");
                   9248:        }
                   9249:        return bIsWow64 != FALSE;
                   9250: }
                   9251: #endif
1.177     brouard  9252: 
1.191     brouard  9253: void syscompilerinfo(int logged)
1.167     brouard  9254:  {
                   9255:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9256:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9257:    /* /GS /W3 /Gy
                   9258:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9259:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9260:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9261:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9262:    */ 
                   9263:    /* 64 bits */
1.185     brouard  9264:    /*
                   9265:      /GS /W3 /Gy
                   9266:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9267:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9268:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9269:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9270:    /* Optimization are useless and O3 is slower than O2 */
                   9271:    /*
                   9272:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9273:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9274:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9275:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9276:    */
1.186     brouard  9277:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9278:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9279:       /PDB:"visual studio
                   9280:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9281:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9282:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9283:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9284:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9285:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9286:       uiAccess='false'"
                   9287:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9288:       /NOLOGO /TLBID:1
                   9289:    */
1.177     brouard  9290: #if defined __INTEL_COMPILER
1.178     brouard  9291: #if defined(__GNUC__)
                   9292:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9293: #endif
1.177     brouard  9294: #elif defined(__GNUC__) 
1.179     brouard  9295: #ifndef  __APPLE__
1.174     brouard  9296: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9297: #endif
1.177     brouard  9298:    struct utsname sysInfo;
1.178     brouard  9299:    int cross = CROSS;
                   9300:    if (cross){
                   9301:           printf("Cross-");
1.191     brouard  9302:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9303:    }
1.174     brouard  9304: #endif
                   9305: 
1.171     brouard  9306: #include <stdint.h>
1.178     brouard  9307: 
1.191     brouard  9308:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9309: #if defined(__clang__)
1.191     brouard  9310:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9311: #endif
                   9312: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9313:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9314: #endif
                   9315: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9316:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9317: #endif
                   9318: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9319:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9320: #endif
                   9321: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9322:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9323: #endif
                   9324: #if defined(_MSC_VER)
1.191     brouard  9325:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9326: #endif
                   9327: #if defined(__PGI)
1.191     brouard  9328:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9329: #endif
                   9330: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9331:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9332: #endif
1.191     brouard  9333:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9334:    
1.167     brouard  9335: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9336: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9337:     // Windows (x64 and x86)
1.191     brouard  9338:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9339: #elif __unix__ // all unices, not all compilers
                   9340:     // Unix
1.191     brouard  9341:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9342: #elif __linux__
                   9343:     // linux
1.191     brouard  9344:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9345: #elif __APPLE__
1.174     brouard  9346:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9347:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9348: #endif
                   9349: 
                   9350: /*  __MINGW32__          */
                   9351: /*  __CYGWIN__  */
                   9352: /* __MINGW64__  */
                   9353: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9354: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9355: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9356: /* _WIN64  // Defined for applications for Win64. */
                   9357: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9358: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9359: 
1.167     brouard  9360: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9361:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9362: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9363:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9364: #else
1.191     brouard  9365:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9366: #endif
                   9367: 
1.169     brouard  9368: #if defined(__GNUC__)
                   9369: # if defined(__GNUC_PATCHLEVEL__)
                   9370: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9371:                             + __GNUC_MINOR__ * 100 \
                   9372:                             + __GNUC_PATCHLEVEL__)
                   9373: # else
                   9374: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9375:                             + __GNUC_MINOR__ * 100)
                   9376: # endif
1.174     brouard  9377:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9378:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9379: 
                   9380:    if (uname(&sysInfo) != -1) {
                   9381:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9382:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9383:    }
                   9384:    else
                   9385:       perror("uname() error");
1.179     brouard  9386:    //#ifndef __INTEL_COMPILER 
                   9387: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9388:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9389:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9390: #endif
1.169     brouard  9391: #endif
1.172     brouard  9392: 
                   9393:    //   void main()
                   9394:    //   {
1.169     brouard  9395: #if defined(_MSC_VER)
1.174     brouard  9396:    if (IsWow64()){
1.191     brouard  9397:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9398:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9399:    }
                   9400:    else{
1.191     brouard  9401:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9402:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9403:    }
1.172     brouard  9404:    //     printf("\nPress Enter to continue...");
                   9405:    //     getchar();
                   9406:    //   }
                   9407: 
1.169     brouard  9408: #endif
                   9409:    
1.167     brouard  9410: 
1.219     brouard  9411: }
1.136     brouard  9412: 
1.219     brouard  9413: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9414:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9415:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9416:   /* double ftolpl = 1.e-10; */
1.180     brouard  9417:   double age, agebase, agelim;
1.203     brouard  9418:   double tot;
1.180     brouard  9419: 
1.202     brouard  9420:   strcpy(filerespl,"PL_");
                   9421:   strcat(filerespl,fileresu);
                   9422:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9423:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9424:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9425:   }
1.227     brouard  9426:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9427:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9428:   pstamp(ficrespl);
1.203     brouard  9429:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9430:   fprintf(ficrespl,"#Age ");
                   9431:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9432:   fprintf(ficrespl,"\n");
1.180     brouard  9433:   
1.219     brouard  9434:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9435: 
1.219     brouard  9436:   agebase=ageminpar;
                   9437:   agelim=agemaxpar;
1.180     brouard  9438: 
1.227     brouard  9439:   /* i1=pow(2,ncoveff); */
1.234     brouard  9440:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9441:   if (cptcovn < 1){i1=1;}
1.180     brouard  9442: 
1.238     brouard  9443:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9444:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9445:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9446:        continue;
1.235     brouard  9447: 
1.238     brouard  9448:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9449:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9450:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9451:       /* k=k+1; */
                   9452:       /* to clean */
                   9453:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9454:       fprintf(ficrespl,"#******");
                   9455:       printf("#******");
                   9456:       fprintf(ficlog,"#******");
                   9457:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9458:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9459:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9460:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9461:       }
                   9462:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9463:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9464:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9465:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9466:       }
                   9467:       fprintf(ficrespl,"******\n");
                   9468:       printf("******\n");
                   9469:       fprintf(ficlog,"******\n");
                   9470:       if(invalidvarcomb[k]){
                   9471:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9472:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9473:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9474:        continue;
                   9475:       }
1.219     brouard  9476: 
1.238     brouard  9477:       fprintf(ficrespl,"#Age ");
                   9478:       for(j=1;j<=cptcoveff;j++) {
                   9479:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9480:       }
                   9481:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9482:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9483:     
1.238     brouard  9484:       for (age=agebase; age<=agelim; age++){
                   9485:        /* for (age=agebase; age<=agebase; age++){ */
                   9486:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9487:        fprintf(ficrespl,"%.0f ",age );
                   9488:        for(j=1;j<=cptcoveff;j++)
                   9489:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9490:        tot=0.;
                   9491:        for(i=1; i<=nlstate;i++){
                   9492:          tot +=  prlim[i][i];
                   9493:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9494:        }
                   9495:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9496:       } /* Age */
                   9497:       /* was end of cptcod */
                   9498:     } /* cptcov */
                   9499:   } /* nres */
1.219     brouard  9500:   return 0;
1.180     brouard  9501: }
                   9502: 
1.218     brouard  9503: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9504:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9505:        
                   9506:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9507:    * at any age between ageminpar and agemaxpar
                   9508:         */
1.235     brouard  9509:   int i, j, k, i1, nres=0 ;
1.217     brouard  9510:   /* double ftolpl = 1.e-10; */
                   9511:   double age, agebase, agelim;
                   9512:   double tot;
1.218     brouard  9513:   /* double ***mobaverage; */
                   9514:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9515: 
                   9516:   strcpy(fileresplb,"PLB_");
                   9517:   strcat(fileresplb,fileresu);
                   9518:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9519:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9520:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9521:   }
                   9522:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9523:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9524:   pstamp(ficresplb);
                   9525:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9526:   fprintf(ficresplb,"#Age ");
                   9527:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9528:   fprintf(ficresplb,"\n");
                   9529:   
1.218     brouard  9530:   
                   9531:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9532:   
                   9533:   agebase=ageminpar;
                   9534:   agelim=agemaxpar;
                   9535:   
                   9536:   
1.227     brouard  9537:   i1=pow(2,cptcoveff);
1.218     brouard  9538:   if (cptcovn < 1){i1=1;}
1.227     brouard  9539:   
1.238     brouard  9540:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9541:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9542:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9543:        continue;
                   9544:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9545:       fprintf(ficresplb,"#******");
                   9546:       printf("#******");
                   9547:       fprintf(ficlog,"#******");
                   9548:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9549:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9550:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9551:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9552:       }
                   9553:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9554:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9555:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9556:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9557:       }
                   9558:       fprintf(ficresplb,"******\n");
                   9559:       printf("******\n");
                   9560:       fprintf(ficlog,"******\n");
                   9561:       if(invalidvarcomb[k]){
                   9562:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9563:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9564:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9565:        continue;
                   9566:       }
1.218     brouard  9567:     
1.238     brouard  9568:       fprintf(ficresplb,"#Age ");
                   9569:       for(j=1;j<=cptcoveff;j++) {
                   9570:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9571:       }
                   9572:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9573:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9574:     
                   9575:     
1.238     brouard  9576:       for (age=agebase; age<=agelim; age++){
                   9577:        /* for (age=agebase; age<=agebase; age++){ */
                   9578:        if(mobilavproj > 0){
                   9579:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9580:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9581:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9582:        }else if (mobilavproj == 0){
                   9583:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9584:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9585:          exit(1);
                   9586:        }else{
                   9587:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9588:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9589:        }
                   9590:        fprintf(ficresplb,"%.0f ",age );
                   9591:        for(j=1;j<=cptcoveff;j++)
                   9592:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9593:        tot=0.;
                   9594:        for(i=1; i<=nlstate;i++){
                   9595:          tot +=  bprlim[i][i];
                   9596:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9597:        }
                   9598:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9599:       } /* Age */
                   9600:       /* was end of cptcod */
1.255     brouard  9601:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9602:     } /* end of any combination */
                   9603:   } /* end of nres */  
1.218     brouard  9604:   /* hBijx(p, bage, fage); */
                   9605:   /* fclose(ficrespijb); */
                   9606:   
                   9607:   return 0;
1.217     brouard  9608: }
1.218     brouard  9609:  
1.180     brouard  9610: int hPijx(double *p, int bage, int fage){
                   9611:     /*------------- h Pij x at various ages ------------*/
                   9612: 
                   9613:   int stepsize;
                   9614:   int agelim;
                   9615:   int hstepm;
                   9616:   int nhstepm;
1.235     brouard  9617:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9618: 
                   9619:   double agedeb;
                   9620:   double ***p3mat;
                   9621: 
1.201     brouard  9622:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9623:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9624:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9625:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9626:     }
                   9627:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9628:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9629:   
                   9630:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9631:     /*if (stepm<=24) stepsize=2;*/
                   9632: 
                   9633:     agelim=AGESUP;
                   9634:     hstepm=stepsize*YEARM; /* Every year of age */
                   9635:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9636:                
1.180     brouard  9637:     /* hstepm=1;   aff par mois*/
                   9638:     pstamp(ficrespij);
                   9639:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9640:     i1= pow(2,cptcoveff);
1.218     brouard  9641:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9642:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9643:                /*      k=k+1;  */
1.235     brouard  9644:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9645:     for(k=1; k<=i1;k++){
1.253     brouard  9646:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9647:        continue;
1.183     brouard  9648:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9649:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9650:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9651:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9652:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9653:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9654:       }
1.183     brouard  9655:       fprintf(ficrespij,"******\n");
                   9656:       
                   9657:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9658:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9659:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9660:        
                   9661:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9662:        
1.183     brouard  9663:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9664:        oldm=oldms;savm=savms;
1.235     brouard  9665:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9666:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9667:        for(i=1; i<=nlstate;i++)
                   9668:          for(j=1; j<=nlstate+ndeath;j++)
                   9669:            fprintf(ficrespij," %1d-%1d",i,j);
                   9670:        fprintf(ficrespij,"\n");
                   9671:        for (h=0; h<=nhstepm; h++){
                   9672:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9673:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9674:          for(i=1; i<=nlstate;i++)
                   9675:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9676:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9677:          fprintf(ficrespij,"\n");
                   9678:        }
1.183     brouard  9679:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9680:        fprintf(ficrespij,"\n");
                   9681:       }
1.180     brouard  9682:       /*}*/
                   9683:     }
1.218     brouard  9684:     return 0;
1.180     brouard  9685: }
1.218     brouard  9686:  
                   9687:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9688:     /*------------- h Bij x at various ages ------------*/
                   9689: 
                   9690:   int stepsize;
1.218     brouard  9691:   /* int agelim; */
                   9692:        int ageminl;
1.217     brouard  9693:   int hstepm;
                   9694:   int nhstepm;
1.238     brouard  9695:   int h, i, i1, j, k, nres;
1.218     brouard  9696:        
1.217     brouard  9697:   double agedeb;
                   9698:   double ***p3mat;
1.218     brouard  9699:        
                   9700:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9701:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9702:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9703:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9704:   }
                   9705:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9706:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9707:   
                   9708:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9709:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9710:   
1.218     brouard  9711:   /* agelim=AGESUP; */
                   9712:   ageminl=30;
                   9713:   hstepm=stepsize*YEARM; /* Every year of age */
                   9714:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9715:   
                   9716:   /* hstepm=1;   aff par mois*/
                   9717:   pstamp(ficrespijb);
1.255     brouard  9718:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9719:   i1= pow(2,cptcoveff);
1.218     brouard  9720:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9721:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9722:   /*   k=k+1;  */
1.238     brouard  9723:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9724:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9725:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9726:        continue;
                   9727:       fprintf(ficrespijb,"\n#****** ");
                   9728:       for(j=1;j<=cptcoveff;j++)
                   9729:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9730:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9731:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9732:       }
                   9733:       fprintf(ficrespijb,"******\n");
                   9734:       if(invalidvarcomb[k]){
                   9735:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9736:        continue;
                   9737:       }
                   9738:       
                   9739:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9740:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9741:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9742:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9743:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9744:        
                   9745:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9746:        
                   9747:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9748:        /* oldm=oldms;savm=savms; */
                   9749:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9750:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9751:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9752:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9753:        for(i=1; i<=nlstate;i++)
                   9754:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9755:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9756:        fprintf(ficrespijb,"\n");
1.238     brouard  9757:        for (h=0; h<=nhstepm; h++){
                   9758:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9759:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9760:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9761:          for(i=1; i<=nlstate;i++)
                   9762:            for(j=1; j<=nlstate+ndeath;j++)
                   9763:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9764:          fprintf(ficrespijb,"\n");
                   9765:        }
                   9766:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9767:        fprintf(ficrespijb,"\n");
                   9768:       } /* end age deb */
                   9769:     } /* end combination */
                   9770:   } /* end nres */
1.218     brouard  9771:   return 0;
                   9772:  } /*  hBijx */
1.217     brouard  9773: 
1.180     brouard  9774: 
1.136     brouard  9775: /***********************************************/
                   9776: /**************** Main Program *****************/
                   9777: /***********************************************/
                   9778: 
                   9779: int main(int argc, char *argv[])
                   9780: {
                   9781: #ifdef GSL
                   9782:   const gsl_multimin_fminimizer_type *T;
                   9783:   size_t iteri = 0, it;
                   9784:   int rval = GSL_CONTINUE;
                   9785:   int status = GSL_SUCCESS;
                   9786:   double ssval;
                   9787: #endif
                   9788:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9789:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9790:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9791:   int jj, ll, li, lj, lk;
1.136     brouard  9792:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9793:   int num_filled;
1.136     brouard  9794:   int itimes;
                   9795:   int NDIM=2;
                   9796:   int vpopbased=0;
1.235     brouard  9797:   int nres=0;
1.258     brouard  9798:   int endishere=0;
1.136     brouard  9799: 
1.164     brouard  9800:   char ca[32], cb[32];
1.136     brouard  9801:   /*  FILE *fichtm; *//* Html File */
                   9802:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9803:   struct stat info;
1.191     brouard  9804:   double agedeb=0.;
1.194     brouard  9805: 
                   9806:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9807:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9808: 
1.165     brouard  9809:   double fret;
1.191     brouard  9810:   double dum=0.; /* Dummy variable */
1.136     brouard  9811:   double ***p3mat;
1.218     brouard  9812:   /* double ***mobaverage; */
1.164     brouard  9813: 
                   9814:   char line[MAXLINE];
1.197     brouard  9815:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9816: 
1.234     brouard  9817:   char  modeltemp[MAXLINE];
1.230     brouard  9818:   char resultline[MAXLINE];
                   9819:   
1.136     brouard  9820:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9821:   char *tok, *val; /* pathtot */
1.136     brouard  9822:   int firstobs=1, lastobs=10;
1.195     brouard  9823:   int c,  h , cpt, c2;
1.191     brouard  9824:   int jl=0;
                   9825:   int i1, j1, jk, stepsize=0;
1.194     brouard  9826:   int count=0;
                   9827: 
1.164     brouard  9828:   int *tab; 
1.136     brouard  9829:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9830:   int backcast=0;
1.136     brouard  9831:   int mobilav=0,popforecast=0;
1.191     brouard  9832:   int hstepm=0, nhstepm=0;
1.136     brouard  9833:   int agemortsup;
                   9834:   float  sumlpop=0.;
                   9835:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9836:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9837: 
1.191     brouard  9838:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9839:   double ftolpl=FTOL;
                   9840:   double **prlim;
1.217     brouard  9841:   double **bprlim;
1.136     brouard  9842:   double ***param; /* Matrix of parameters */
1.251     brouard  9843:   double ***paramstart; /* Matrix of starting parameter values */
                   9844:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9845:   double **matcov; /* Matrix of covariance */
1.203     brouard  9846:   double **hess; /* Hessian matrix */
1.136     brouard  9847:   double ***delti3; /* Scale */
                   9848:   double *delti; /* Scale */
                   9849:   double ***eij, ***vareij;
                   9850:   double **varpl; /* Variances of prevalence limits by age */
                   9851:   double *epj, vepp;
1.164     brouard  9852: 
1.136     brouard  9853:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9854:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9855: 
1.136     brouard  9856:   double **ximort;
1.145     brouard  9857:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9858:   int *dcwave;
                   9859: 
1.164     brouard  9860:   char z[1]="c";
1.136     brouard  9861: 
                   9862:   /*char  *strt;*/
                   9863:   char strtend[80];
1.126     brouard  9864: 
1.164     brouard  9865: 
1.126     brouard  9866: /*   setlocale (LC_ALL, ""); */
                   9867: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9868: /*   textdomain (PACKAGE); */
                   9869: /*   setlocale (LC_CTYPE, ""); */
                   9870: /*   setlocale (LC_MESSAGES, ""); */
                   9871: 
                   9872:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9873:   rstart_time = time(NULL);  
                   9874:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9875:   start_time = *localtime(&rstart_time);
1.126     brouard  9876:   curr_time=start_time;
1.157     brouard  9877:   /*tml = *localtime(&start_time.tm_sec);*/
                   9878:   /* strcpy(strstart,asctime(&tml)); */
                   9879:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9880: 
                   9881: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9882: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9883: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9884: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9885: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9886: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9887: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9888: /*   strt=asctime(&tmg); */
                   9889: /*   printf("Time(after) =%s",strstart);  */
                   9890: /*  (void) time (&time_value);
                   9891: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9892: *  tm = *localtime(&time_value);
                   9893: *  strstart=asctime(&tm);
                   9894: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9895: */
                   9896: 
                   9897:   nberr=0; /* Number of errors and warnings */
                   9898:   nbwarn=0;
1.184     brouard  9899: #ifdef WIN32
                   9900:   _getcwd(pathcd, size);
                   9901: #else
1.126     brouard  9902:   getcwd(pathcd, size);
1.184     brouard  9903: #endif
1.191     brouard  9904:   syscompilerinfo(0);
1.196     brouard  9905:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9906:   if(argc <=1){
                   9907:     printf("\nEnter the parameter file name: ");
1.205     brouard  9908:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9909:       printf("ERROR Empty parameter file name\n");
                   9910:       goto end;
                   9911:     }
1.126     brouard  9912:     i=strlen(pathr);
                   9913:     if(pathr[i-1]=='\n')
                   9914:       pathr[i-1]='\0';
1.156     brouard  9915:     i=strlen(pathr);
1.205     brouard  9916:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9917:       pathr[i-1]='\0';
1.205     brouard  9918:     }
                   9919:     i=strlen(pathr);
                   9920:     if( i==0 ){
                   9921:       printf("ERROR Empty parameter file name\n");
                   9922:       goto end;
                   9923:     }
                   9924:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9925:       printf("Pathr |%s|\n",pathr);
                   9926:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9927:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9928:       strcpy (pathtot, val);
                   9929:       if(pathr[0] == '\0') break; /* Dirty */
                   9930:     }
                   9931:   }
                   9932:   else{
                   9933:     strcpy(pathtot,argv[1]);
                   9934:   }
                   9935:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9936:   /*cygwin_split_path(pathtot,path,optionfile);
                   9937:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9938:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9939: 
                   9940:   /* Split argv[0], imach program to get pathimach */
                   9941:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9942:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9943:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9944:  /*   strcpy(pathimach,argv[0]); */
                   9945:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9946:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9947:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9948: #ifdef WIN32
                   9949:   _chdir(path); /* Can be a relative path */
                   9950:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9951: #else
1.126     brouard  9952:   chdir(path); /* Can be a relative path */
1.184     brouard  9953:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9954: #endif
                   9955:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9956:   strcpy(command,"mkdir ");
                   9957:   strcat(command,optionfilefiname);
                   9958:   if((outcmd=system(command)) != 0){
1.169     brouard  9959:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9960:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9961:     /* fclose(ficlog); */
                   9962: /*     exit(1); */
                   9963:   }
                   9964: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9965: /*     perror("mkdir"); */
                   9966: /*   } */
                   9967: 
                   9968:   /*-------- arguments in the command line --------*/
                   9969: 
1.186     brouard  9970:   /* Main Log file */
1.126     brouard  9971:   strcat(filelog, optionfilefiname);
                   9972:   strcat(filelog,".log");    /* */
                   9973:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9974:     printf("Problem with logfile %s\n",filelog);
                   9975:     goto end;
                   9976:   }
                   9977:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9978:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9979:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9980:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9981:  path=%s \n\
                   9982:  optionfile=%s\n\
                   9983:  optionfilext=%s\n\
1.156     brouard  9984:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9985: 
1.197     brouard  9986:   syscompilerinfo(1);
1.167     brouard  9987: 
1.126     brouard  9988:   printf("Local time (at start):%s",strstart);
                   9989:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9990:   fflush(ficlog);
                   9991: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9992: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9993: 
                   9994:   /* */
                   9995:   strcpy(fileres,"r");
                   9996:   strcat(fileres, optionfilefiname);
1.201     brouard  9997:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9998:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9999:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10000: 
1.186     brouard  10001:   /* Main ---------arguments file --------*/
1.126     brouard  10002: 
                   10003:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10004:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10005:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10006:     fflush(ficlog);
1.149     brouard  10007:     /* goto end; */
                   10008:     exit(70); 
1.126     brouard  10009:   }
                   10010: 
                   10011: 
                   10012: 
                   10013:   strcpy(filereso,"o");
1.201     brouard  10014:   strcat(filereso,fileresu);
1.126     brouard  10015:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10016:     printf("Problem with Output resultfile: %s\n", filereso);
                   10017:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10018:     fflush(ficlog);
                   10019:     goto end;
                   10020:   }
                   10021: 
                   10022:   /* Reads comments: lines beginning with '#' */
                   10023:   numlinepar=0;
1.197     brouard  10024: 
                   10025:     /* First parameter line */
                   10026:   while(fgets(line, MAXLINE, ficpar)) {
                   10027:     /* If line starts with a # it is a comment */
                   10028:     if (line[0] == '#') {
                   10029:       numlinepar++;
                   10030:       fputs(line,stdout);
                   10031:       fputs(line,ficparo);
                   10032:       fputs(line,ficlog);
                   10033:       continue;
                   10034:     }else
                   10035:       break;
                   10036:   }
                   10037:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10038:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10039:     if (num_filled != 5) {
                   10040:       printf("Should be 5 parameters\n");
                   10041:     }
1.126     brouard  10042:     numlinepar++;
1.197     brouard  10043:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10044:   }
                   10045:   /* Second parameter line */
                   10046:   while(fgets(line, MAXLINE, ficpar)) {
                   10047:     /* If line starts with a # it is a comment */
                   10048:     if (line[0] == '#') {
                   10049:       numlinepar++;
                   10050:       fputs(line,stdout);
                   10051:       fputs(line,ficparo);
                   10052:       fputs(line,ficlog);
                   10053:       continue;
                   10054:     }else
                   10055:       break;
                   10056:   }
1.223     brouard  10057:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10058:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10059:     if (num_filled != 11) {
                   10060:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10061:       printf("but line=%s\n",line);
1.197     brouard  10062:     }
1.223     brouard  10063:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10064:   }
1.203     brouard  10065:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10066:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10067:   /* Third parameter line */
                   10068:   while(fgets(line, MAXLINE, ficpar)) {
                   10069:     /* If line starts with a # it is a comment */
                   10070:     if (line[0] == '#') {
                   10071:       numlinepar++;
                   10072:       fputs(line,stdout);
                   10073:       fputs(line,ficparo);
                   10074:       fputs(line,ficlog);
                   10075:       continue;
                   10076:     }else
                   10077:       break;
                   10078:   }
1.201     brouard  10079:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10080:     if (num_filled == 0)
                   10081:             model[0]='\0';
                   10082:     else if (num_filled != 1){
1.197     brouard  10083:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10084:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10085:       model[0]='\0';
                   10086:       goto end;
                   10087:     }
                   10088:     else{
                   10089:       if (model[0]=='+'){
                   10090:        for(i=1; i<=strlen(model);i++)
                   10091:          modeltemp[i-1]=model[i];
1.201     brouard  10092:        strcpy(model,modeltemp); 
1.197     brouard  10093:       }
                   10094:     }
1.199     brouard  10095:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10096:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10097:   }
                   10098:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10099:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10100:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10101:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10102:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10103:   fflush(ficlog);
1.190     brouard  10104:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10105:   if(model[0]=='#'){
1.187     brouard  10106:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10107:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10108:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10109:     if(mle != -1){
                   10110:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10111:       exit(1);
                   10112:     }
                   10113:   }
1.126     brouard  10114:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10115:     ungetc(c,ficpar);
                   10116:     fgets(line, MAXLINE, ficpar);
                   10117:     numlinepar++;
1.195     brouard  10118:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10119:       z[0]=line[1];
                   10120:     }
                   10121:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10122:     fputs(line, stdout);
                   10123:     //puts(line);
1.126     brouard  10124:     fputs(line,ficparo);
                   10125:     fputs(line,ficlog);
                   10126:   }
                   10127:   ungetc(c,ficpar);
                   10128: 
                   10129:    
1.145     brouard  10130:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10131:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10132:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10133:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10134:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10135:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10136:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10137:   */
                   10138:   if (strlen(model)>1) 
1.187     brouard  10139:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10140:   else
1.187     brouard  10141:     ncovmodel=2; /* Constant and age */
1.133     brouard  10142:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10143:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10144:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10145:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10146:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10147:     fflush(stdout);
                   10148:     fclose (ficlog);
                   10149:     goto end;
                   10150:   }
1.126     brouard  10151:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10152:   delti=delti3[1][1];
                   10153:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10154:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10155: /* We could also provide initial parameters values giving by simple logistic regression 
                   10156:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10157:       /* for(i=1;i<nlstate;i++){ */
                   10158:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10159:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10160:       /* } */
1.126     brouard  10161:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10162:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10163:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10164:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10165:     fclose (ficparo);
                   10166:     fclose (ficlog);
                   10167:     goto end;
                   10168:     exit(0);
1.220     brouard  10169:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10170:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10171:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10172:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10173:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10174:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10175:     hess=matrix(1,npar,1,npar);
1.220     brouard  10176:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10177:     /* Read guessed parameters */
1.126     brouard  10178:     /* Reads comments: lines beginning with '#' */
                   10179:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10180:       ungetc(c,ficpar);
                   10181:       fgets(line, MAXLINE, ficpar);
                   10182:       numlinepar++;
1.141     brouard  10183:       fputs(line,stdout);
1.126     brouard  10184:       fputs(line,ficparo);
                   10185:       fputs(line,ficlog);
                   10186:     }
                   10187:     ungetc(c,ficpar);
                   10188:     
                   10189:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10190:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10191:     for(i=1; i <=nlstate; i++){
1.234     brouard  10192:       j=0;
1.126     brouard  10193:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10194:        if(jj==i) continue;
                   10195:        j++;
                   10196:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10197:        if ((i1 != i) || (j1 != jj)){
                   10198:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10199: It might be a problem of design; if ncovcol and the model are correct\n \
                   10200: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10201:          exit(1);
                   10202:        }
                   10203:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10204:        if(mle==1)
                   10205:          printf("%1d%1d",i,jj);
                   10206:        fprintf(ficlog,"%1d%1d",i,jj);
                   10207:        for(k=1; k<=ncovmodel;k++){
                   10208:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10209:          if(mle==1){
                   10210:            printf(" %lf",param[i][j][k]);
                   10211:            fprintf(ficlog," %lf",param[i][j][k]);
                   10212:          }
                   10213:          else
                   10214:            fprintf(ficlog," %lf",param[i][j][k]);
                   10215:          fprintf(ficparo," %lf",param[i][j][k]);
                   10216:        }
                   10217:        fscanf(ficpar,"\n");
                   10218:        numlinepar++;
                   10219:        if(mle==1)
                   10220:          printf("\n");
                   10221:        fprintf(ficlog,"\n");
                   10222:        fprintf(ficparo,"\n");
1.126     brouard  10223:       }
                   10224:     }  
                   10225:     fflush(ficlog);
1.234     brouard  10226:     
1.251     brouard  10227:     /* Reads parameters values */
1.126     brouard  10228:     p=param[1][1];
1.251     brouard  10229:     pstart=paramstart[1][1];
1.126     brouard  10230:     
                   10231:     /* Reads comments: lines beginning with '#' */
                   10232:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10233:       ungetc(c,ficpar);
                   10234:       fgets(line, MAXLINE, ficpar);
                   10235:       numlinepar++;
1.141     brouard  10236:       fputs(line,stdout);
1.126     brouard  10237:       fputs(line,ficparo);
                   10238:       fputs(line,ficlog);
                   10239:     }
                   10240:     ungetc(c,ficpar);
                   10241: 
                   10242:     for(i=1; i <=nlstate; i++){
                   10243:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10244:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10245:        if ( (i1-i) * (j1-j) != 0){
                   10246:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10247:          exit(1);
                   10248:        }
                   10249:        printf("%1d%1d",i,j);
                   10250:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10251:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10252:        for(k=1; k<=ncovmodel;k++){
                   10253:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10254:          printf(" %le",delti3[i][j][k]);
                   10255:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10256:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10257:        }
                   10258:        fscanf(ficpar,"\n");
                   10259:        numlinepar++;
                   10260:        printf("\n");
                   10261:        fprintf(ficparo,"\n");
                   10262:        fprintf(ficlog,"\n");
1.126     brouard  10263:       }
                   10264:     }
                   10265:     fflush(ficlog);
1.234     brouard  10266:     
1.145     brouard  10267:     /* Reads covariance matrix */
1.126     brouard  10268:     delti=delti3[1][1];
1.220     brouard  10269:                
                   10270:                
1.126     brouard  10271:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10272:                
1.126     brouard  10273:     /* Reads comments: lines beginning with '#' */
                   10274:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10275:       ungetc(c,ficpar);
                   10276:       fgets(line, MAXLINE, ficpar);
                   10277:       numlinepar++;
1.141     brouard  10278:       fputs(line,stdout);
1.126     brouard  10279:       fputs(line,ficparo);
                   10280:       fputs(line,ficlog);
                   10281:     }
                   10282:     ungetc(c,ficpar);
1.220     brouard  10283:                
1.126     brouard  10284:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10285:     hess=matrix(1,npar,1,npar);
1.131     brouard  10286:     for(i=1; i <=npar; i++)
                   10287:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10288:                
1.194     brouard  10289:     /* Scans npar lines */
1.126     brouard  10290:     for(i=1; i <=npar; i++){
1.226     brouard  10291:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10292:       if(count != 3){
1.226     brouard  10293:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10294: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10295: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10296:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10297: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10298: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10299:        exit(1);
1.220     brouard  10300:       }else{
1.226     brouard  10301:        if(mle==1)
                   10302:          printf("%1d%1d%d",i1,j1,jk);
                   10303:       }
                   10304:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10305:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10306:       for(j=1; j <=i; j++){
1.226     brouard  10307:        fscanf(ficpar," %le",&matcov[i][j]);
                   10308:        if(mle==1){
                   10309:          printf(" %.5le",matcov[i][j]);
                   10310:        }
                   10311:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10312:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10313:       }
                   10314:       fscanf(ficpar,"\n");
                   10315:       numlinepar++;
                   10316:       if(mle==1)
1.220     brouard  10317:                                printf("\n");
1.126     brouard  10318:       fprintf(ficlog,"\n");
                   10319:       fprintf(ficparo,"\n");
                   10320:     }
1.194     brouard  10321:     /* End of read covariance matrix npar lines */
1.126     brouard  10322:     for(i=1; i <=npar; i++)
                   10323:       for(j=i+1;j<=npar;j++)
1.226     brouard  10324:        matcov[i][j]=matcov[j][i];
1.126     brouard  10325:     
                   10326:     if(mle==1)
                   10327:       printf("\n");
                   10328:     fprintf(ficlog,"\n");
                   10329:     
                   10330:     fflush(ficlog);
                   10331:     
                   10332:     /*-------- Rewriting parameter file ----------*/
                   10333:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10334:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10335:     strcat(rfileres,".");    /* */
                   10336:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10337:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10338:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10339:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10340:     }
                   10341:     fprintf(ficres,"#%s\n",version);
                   10342:   }    /* End of mle != -3 */
1.218     brouard  10343:   
1.186     brouard  10344:   /*  Main data
                   10345:    */
1.126     brouard  10346:   n= lastobs;
                   10347:   num=lvector(1,n);
                   10348:   moisnais=vector(1,n);
                   10349:   annais=vector(1,n);
                   10350:   moisdc=vector(1,n);
                   10351:   andc=vector(1,n);
1.220     brouard  10352:   weight=vector(1,n);
1.126     brouard  10353:   agedc=vector(1,n);
                   10354:   cod=ivector(1,n);
1.220     brouard  10355:   for(i=1;i<=n;i++){
1.234     brouard  10356:     num[i]=0;
                   10357:     moisnais[i]=0;
                   10358:     annais[i]=0;
                   10359:     moisdc[i]=0;
                   10360:     andc[i]=0;
                   10361:     agedc[i]=0;
                   10362:     cod[i]=0;
                   10363:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10364:   }
1.126     brouard  10365:   mint=matrix(1,maxwav,1,n);
                   10366:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10367:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10368:   tab=ivector(1,NCOVMAX);
1.144     brouard  10369:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10370:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10371: 
1.136     brouard  10372:   /* Reads data from file datafile */
                   10373:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10374:     goto end;
                   10375: 
                   10376:   /* Calculation of the number of parameters from char model */
1.234     brouard  10377:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10378:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10379:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10380:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10381:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10382:   */
                   10383:   
                   10384:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10385:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10386:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10387:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10388:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10389:   TvarF=ivector(1,NCOVMAX); /*  */
                   10390:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10391:   TvarV=ivector(1,NCOVMAX); /*  */
                   10392:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10393:   TvarA=ivector(1,NCOVMAX); /*  */
                   10394:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10395:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10396:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10397:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10398:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10399:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10400:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10401:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10402:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10403: 
1.230     brouard  10404:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10405:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10406:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10407:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10408:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10409:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10410:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10411:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10412:   */
                   10413:   /* For model-covariate k tells which data-covariate to use but
                   10414:     because this model-covariate is a construction we invent a new column
                   10415:     ncovcol + k1
                   10416:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10417:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10418:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10419:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10420:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10421:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10422:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10423:   */
1.145     brouard  10424:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10425:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10426:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10427:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10428:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10429:                         4 covariates (3 plus signs)
                   10430:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10431:                      */  
1.230     brouard  10432:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10433:                                * individual dummy, fixed or varying:
                   10434:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10435:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10436:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10437:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10438:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10439:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10440:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10441:                                * individual quantitative, fixed or varying:
                   10442:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10443:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10444:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10445: /* Main decodemodel */
                   10446: 
1.187     brouard  10447: 
1.223     brouard  10448:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10449:     goto end;
                   10450: 
1.137     brouard  10451:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10452:     nbwarn++;
                   10453:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10454:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10455:   }
1.136     brouard  10456:     /*  if(mle==1){*/
1.137     brouard  10457:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10458:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10459:   }
                   10460: 
                   10461:     /*-calculation of age at interview from date of interview and age at death -*/
                   10462:   agev=matrix(1,maxwav,1,imx);
                   10463: 
                   10464:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10465:     goto end;
                   10466: 
1.126     brouard  10467: 
1.136     brouard  10468:   agegomp=(int)agemin;
                   10469:   free_vector(moisnais,1,n);
                   10470:   free_vector(annais,1,n);
1.126     brouard  10471:   /* free_matrix(mint,1,maxwav,1,n);
                   10472:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10473:   /* free_vector(moisdc,1,n); */
                   10474:   /* free_vector(andc,1,n); */
1.145     brouard  10475:   /* */
                   10476:   
1.126     brouard  10477:   wav=ivector(1,imx);
1.214     brouard  10478:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10479:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10480:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10481:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10482:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10483:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10484:    
                   10485:   /* Concatenates waves */
1.214     brouard  10486:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10487:      Death is a valid wave (if date is known).
                   10488:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10489:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10490:      and mw[mi+1][i]. dh depends on stepm.
                   10491:   */
                   10492: 
1.126     brouard  10493:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10494:   /* Concatenates waves */
1.145     brouard  10495:  
1.215     brouard  10496:   free_vector(moisdc,1,n);
                   10497:   free_vector(andc,1,n);
                   10498: 
1.126     brouard  10499:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10500:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10501:   ncodemax[1]=1;
1.145     brouard  10502:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10503:   cptcoveff=0;
1.220     brouard  10504:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10505:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10506:   }
                   10507:   
                   10508:   ncovcombmax=pow(2,cptcoveff);
                   10509:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10510:   for(i=1;i<ncovcombmax;i++)
                   10511:     invalidvarcomb[i]=0;
                   10512:   
1.211     brouard  10513:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10514:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10515:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10516:   
1.200     brouard  10517:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10518:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10519:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10520:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10521:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10522:    * (currently 0 or 1) in the data.
                   10523:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10524:    * corresponding modality (h,j).
                   10525:    */
                   10526: 
1.145     brouard  10527:   h=0;
                   10528:   /*if (cptcovn > 0) */
1.126     brouard  10529:   m=pow(2,cptcoveff);
                   10530:  
1.144     brouard  10531:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10532:           * For k=4 covariates, h goes from 1 to m=2**k
                   10533:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10534:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10535:           *     h\k   1     2     3     4
1.143     brouard  10536:           *______________________________  
                   10537:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10538:           *     2     2     1     1     1
                   10539:           *     3 i=2 1     2     1     1
                   10540:           *     4     2     2     1     1
                   10541:           *     5 i=3 1 i=2 1     2     1
                   10542:           *     6     2     1     2     1
                   10543:           *     7 i=4 1     2     2     1
                   10544:           *     8     2     2     2     1
1.197     brouard  10545:           *     9 i=5 1 i=3 1 i=2 1     2
                   10546:           *    10     2     1     1     2
                   10547:           *    11 i=6 1     2     1     2
                   10548:           *    12     2     2     1     2
                   10549:           *    13 i=7 1 i=4 1     2     2    
                   10550:           *    14     2     1     2     2
                   10551:           *    15 i=8 1     2     2     2
                   10552:           *    16     2     2     2     2
1.143     brouard  10553:           */
1.212     brouard  10554:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10555:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10556:      * and the value of each covariate?
                   10557:      * V1=1, V2=1, V3=2, V4=1 ?
                   10558:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10559:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10560:      * In order to get the real value in the data, we use nbcode
                   10561:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10562:      * We are keeping this crazy system in order to be able (in the future?) 
                   10563:      * to have more than 2 values (0 or 1) for a covariate.
                   10564:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10565:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10566:      *              bbbbbbbb
                   10567:      *              76543210     
                   10568:      *   h-1        00000101 (6-1=5)
1.219     brouard  10569:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10570:      *           &
                   10571:      *     1        00000001 (1)
1.219     brouard  10572:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10573:      *          +1= 00000001 =1 
1.211     brouard  10574:      *
                   10575:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10576:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10577:      *    >>k'            11
                   10578:      *          &   00000001
                   10579:      *            = 00000001
                   10580:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10581:      * Reverse h=6 and m=16?
                   10582:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10583:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10584:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10585:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10586:      * V3=decodtabm(14,3,2**4)=2
                   10587:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10588:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10589:      *          &1 000000001
                   10590:      *           = 000000001
                   10591:      *         +1= 000000010 =2
                   10592:      *                  2211
                   10593:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10594:      *                  V3=2
1.220     brouard  10595:                 * codtabm and decodtabm are identical
1.211     brouard  10596:      */
                   10597: 
1.145     brouard  10598: 
                   10599:  free_ivector(Ndum,-1,NCOVMAX);
                   10600: 
                   10601: 
1.126     brouard  10602:     
1.186     brouard  10603:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10604:   strcpy(optionfilegnuplot,optionfilefiname);
                   10605:   if(mle==-3)
1.201     brouard  10606:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10607:   strcat(optionfilegnuplot,".gp");
                   10608: 
                   10609:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10610:     printf("Problem with file %s",optionfilegnuplot);
                   10611:   }
                   10612:   else{
1.204     brouard  10613:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10614:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10615:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10616:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10617:   }
                   10618:   /*  fclose(ficgp);*/
1.186     brouard  10619: 
                   10620: 
                   10621:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10622: 
                   10623:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10624:   if(mle==-3)
1.201     brouard  10625:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10626:   strcat(optionfilehtm,".htm");
                   10627:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10628:     printf("Problem with %s \n",optionfilehtm);
                   10629:     exit(0);
1.126     brouard  10630:   }
                   10631: 
                   10632:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10633:   strcat(optionfilehtmcov,"-cov.htm");
                   10634:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10635:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10636:   }
                   10637:   else{
                   10638:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10639: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10640: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10641:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10642:   }
                   10643: 
1.213     brouard  10644:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10645: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10646: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10647: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10648: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10649: \n\
                   10650: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10651:  <ul><li><h4>Parameter files</h4>\n\
                   10652:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10653:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10654:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10655:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10656:  - Date and time at start: %s</ul>\n",\
                   10657:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10658:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10659:          fileres,fileres,\
                   10660:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10661:   fflush(fichtm);
                   10662: 
                   10663:   strcpy(pathr,path);
                   10664:   strcat(pathr,optionfilefiname);
1.184     brouard  10665: #ifdef WIN32
                   10666:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10667: #else
1.126     brouard  10668:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10669: #endif
                   10670:          
1.126     brouard  10671:   
1.220     brouard  10672:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10673:                 and for any valid combination of covariates
1.126     brouard  10674:      and prints on file fileres'p'. */
1.251     brouard  10675:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10676:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10677: 
                   10678:   fprintf(fichtm,"\n");
                   10679:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10680: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10681: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10682:          imx,agemin,agemax,jmin,jmax,jmean);
                   10683:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10684:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10685:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10686:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10687:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10688: 
1.126     brouard  10689:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10690:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10691:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10692: 
                   10693:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10694:   /* For mortality only */
1.126     brouard  10695:   if (mle==-3){
1.136     brouard  10696:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10697:     for(i=1;i<=NDIM;i++)
                   10698:       for(j=1;j<=NDIM;j++)
                   10699:        ximort[i][j]=0.;
1.186     brouard  10700:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10701:     cens=ivector(1,n);
                   10702:     ageexmed=vector(1,n);
                   10703:     agecens=vector(1,n);
                   10704:     dcwave=ivector(1,n);
1.223     brouard  10705:                
1.126     brouard  10706:     for (i=1; i<=imx; i++){
                   10707:       dcwave[i]=-1;
                   10708:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10709:        if (s[m][i]>nlstate) {
                   10710:          dcwave[i]=m;
                   10711:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10712:          break;
                   10713:        }
1.126     brouard  10714:     }
1.226     brouard  10715:     
1.126     brouard  10716:     for (i=1; i<=imx; i++) {
                   10717:       if (wav[i]>0){
1.226     brouard  10718:        ageexmed[i]=agev[mw[1][i]][i];
                   10719:        j=wav[i];
                   10720:        agecens[i]=1.; 
                   10721:        
                   10722:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10723:          agecens[i]=agev[mw[j][i]][i];
                   10724:          cens[i]= 1;
                   10725:        }else if (ageexmed[i]< 1) 
                   10726:          cens[i]= -1;
                   10727:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10728:          cens[i]=0 ;
1.126     brouard  10729:       }
                   10730:       else cens[i]=-1;
                   10731:     }
                   10732:     
                   10733:     for (i=1;i<=NDIM;i++) {
                   10734:       for (j=1;j<=NDIM;j++)
1.226     brouard  10735:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10736:     }
                   10737:     
1.145     brouard  10738:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10739:     /*printf("%lf %lf", p[1], p[2]);*/
                   10740:     
                   10741:     
1.136     brouard  10742: #ifdef GSL
                   10743:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10744: #else
1.126     brouard  10745:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10746: #endif
1.201     brouard  10747:     strcpy(filerespow,"POW-MORT_"); 
                   10748:     strcat(filerespow,fileresu);
1.126     brouard  10749:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10750:       printf("Problem with resultfile: %s\n", filerespow);
                   10751:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10752:     }
1.136     brouard  10753: #ifdef GSL
                   10754:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10755: #else
1.126     brouard  10756:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10757: #endif
1.126     brouard  10758:     /*  for (i=1;i<=nlstate;i++)
                   10759:        for(j=1;j<=nlstate+ndeath;j++)
                   10760:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10761:     */
                   10762:     fprintf(ficrespow,"\n");
1.136     brouard  10763: #ifdef GSL
                   10764:     /* gsl starts here */ 
                   10765:     T = gsl_multimin_fminimizer_nmsimplex;
                   10766:     gsl_multimin_fminimizer *sfm = NULL;
                   10767:     gsl_vector *ss, *x;
                   10768:     gsl_multimin_function minex_func;
                   10769: 
                   10770:     /* Initial vertex size vector */
                   10771:     ss = gsl_vector_alloc (NDIM);
                   10772:     
                   10773:     if (ss == NULL){
                   10774:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10775:     }
                   10776:     /* Set all step sizes to 1 */
                   10777:     gsl_vector_set_all (ss, 0.001);
                   10778: 
                   10779:     /* Starting point */
1.126     brouard  10780:     
1.136     brouard  10781:     x = gsl_vector_alloc (NDIM);
                   10782:     
                   10783:     if (x == NULL){
                   10784:       gsl_vector_free(ss);
                   10785:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10786:     }
                   10787:   
                   10788:     /* Initialize method and iterate */
                   10789:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10790:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10791:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10792:     gsl_vector_set(x, 0, p[1]);
                   10793:     gsl_vector_set(x, 1, p[2]);
                   10794: 
                   10795:     minex_func.f = &gompertz_f;
                   10796:     minex_func.n = NDIM;
                   10797:     minex_func.params = (void *)&p; /* ??? */
                   10798:     
                   10799:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10800:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10801:     
                   10802:     printf("Iterations beginning .....\n\n");
                   10803:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10804: 
                   10805:     iteri=0;
                   10806:     while (rval == GSL_CONTINUE){
                   10807:       iteri++;
                   10808:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10809:       
                   10810:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10811:       fflush(0);
                   10812:       
                   10813:       if (status) 
                   10814:         break;
                   10815:       
                   10816:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10817:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10818:       
                   10819:       if (rval == GSL_SUCCESS)
                   10820:         printf ("converged to a local maximum at\n");
                   10821:       
                   10822:       printf("%5d ", iteri);
                   10823:       for (it = 0; it < NDIM; it++){
                   10824:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10825:       }
                   10826:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10827:     }
                   10828:     
                   10829:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10830:     
                   10831:     gsl_vector_free(x); /* initial values */
                   10832:     gsl_vector_free(ss); /* inital step size */
                   10833:     for (it=0; it<NDIM; it++){
                   10834:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10835:       fprintf(ficrespow," %.12lf", p[it]);
                   10836:     }
                   10837:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10838: #endif
                   10839: #ifdef POWELL
                   10840:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10841: #endif  
1.126     brouard  10842:     fclose(ficrespow);
                   10843:     
1.203     brouard  10844:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10845: 
                   10846:     for(i=1; i <=NDIM; i++)
                   10847:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10848:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10849:     
                   10850:     printf("\nCovariance matrix\n ");
1.203     brouard  10851:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10852:     for(i=1; i <=NDIM; i++) {
                   10853:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10854:                                printf("%f ",matcov[i][j]);
                   10855:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10856:       }
1.203     brouard  10857:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10858:     }
                   10859:     
                   10860:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10861:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10862:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10863:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10864:     }
1.126     brouard  10865:     lsurv=vector(1,AGESUP);
                   10866:     lpop=vector(1,AGESUP);
                   10867:     tpop=vector(1,AGESUP);
                   10868:     lsurv[agegomp]=100000;
                   10869:     
                   10870:     for (k=agegomp;k<=AGESUP;k++) {
                   10871:       agemortsup=k;
                   10872:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10873:     }
                   10874:     
                   10875:     for (k=agegomp;k<agemortsup;k++)
                   10876:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10877:     
                   10878:     for (k=agegomp;k<agemortsup;k++){
                   10879:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10880:       sumlpop=sumlpop+lpop[k];
                   10881:     }
                   10882:     
                   10883:     tpop[agegomp]=sumlpop;
                   10884:     for (k=agegomp;k<(agemortsup-3);k++){
                   10885:       /*  tpop[k+1]=2;*/
                   10886:       tpop[k+1]=tpop[k]-lpop[k];
                   10887:     }
                   10888:     
                   10889:     
                   10890:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10891:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10892:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10893:     
                   10894:     
                   10895:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10896:                ageminpar=50;
                   10897:                agemaxpar=100;
1.194     brouard  10898:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10899:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10900: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10901: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10902:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10903: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10904: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10905:     }else{
                   10906:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10907:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10908:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10909:                }
1.201     brouard  10910:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10911:                     stepm, weightopt,\
                   10912:                     model,imx,p,matcov,agemortsup);
                   10913:     
                   10914:     free_vector(lsurv,1,AGESUP);
                   10915:     free_vector(lpop,1,AGESUP);
                   10916:     free_vector(tpop,1,AGESUP);
1.220     brouard  10917:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10918:     free_ivector(cens,1,n);
                   10919:     free_vector(agecens,1,n);
                   10920:     free_ivector(dcwave,1,n);
1.220     brouard  10921: #ifdef GSL
1.136     brouard  10922: #endif
1.186     brouard  10923:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10924:   /* Standard  */
                   10925:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10926:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10927:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10928:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10929:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10930:     for (k=1; k<=npar;k++)
                   10931:       printf(" %d %8.5f",k,p[k]);
                   10932:     printf("\n");
1.205     brouard  10933:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10934:       /* mlikeli uses func not funcone */
1.247     brouard  10935:       /* for(i=1;i<nlstate;i++){ */
                   10936:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10937:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10938:       /* } */
1.205     brouard  10939:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10940:     }
                   10941:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10942:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10943:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10944:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10945:     }
                   10946:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10947:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10948:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10949:     for (k=1; k<=npar;k++)
                   10950:       printf(" %d %8.5f",k,p[k]);
                   10951:     printf("\n");
                   10952:     
                   10953:     /*--------- results files --------------*/
1.224     brouard  10954:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10955:     
                   10956:     
                   10957:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10958:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10959:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10960:     for(i=1,jk=1; i <=nlstate; i++){
                   10961:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10962:        if (k != i) {
                   10963:          printf("%d%d ",i,k);
                   10964:          fprintf(ficlog,"%d%d ",i,k);
                   10965:          fprintf(ficres,"%1d%1d ",i,k);
                   10966:          for(j=1; j <=ncovmodel; j++){
                   10967:            printf("%12.7f ",p[jk]);
                   10968:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10969:            fprintf(ficres,"%12.7f ",p[jk]);
                   10970:            jk++; 
                   10971:          }
                   10972:          printf("\n");
                   10973:          fprintf(ficlog,"\n");
                   10974:          fprintf(ficres,"\n");
                   10975:        }
1.126     brouard  10976:       }
                   10977:     }
1.203     brouard  10978:     if(mle != 0){
                   10979:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10980:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10981:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10982:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10983:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10984:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10985:        for(k=1; k <=(nlstate+ndeath); k++){
                   10986:          if (k != i) {
                   10987:            printf("%d%d ",i,k);
                   10988:            fprintf(ficlog,"%d%d ",i,k);
                   10989:            for(j=1; j <=ncovmodel; j++){
                   10990:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10991:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10992:              jk++; 
                   10993:            }
                   10994:            printf("\n");
                   10995:            fprintf(ficlog,"\n");
                   10996:          }
                   10997:        }
1.193     brouard  10998:       }
1.203     brouard  10999:     } /* end of hesscov and Wald tests */
1.225     brouard  11000:     
1.203     brouard  11001:     /*  */
1.126     brouard  11002:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11003:     printf("# Scales (for hessian or gradient estimation)\n");
                   11004:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11005:     for(i=1,jk=1; i <=nlstate; i++){
                   11006:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11007:        if (j!=i) {
                   11008:          fprintf(ficres,"%1d%1d",i,j);
                   11009:          printf("%1d%1d",i,j);
                   11010:          fprintf(ficlog,"%1d%1d",i,j);
                   11011:          for(k=1; k<=ncovmodel;k++){
                   11012:            printf(" %.5e",delti[jk]);
                   11013:            fprintf(ficlog," %.5e",delti[jk]);
                   11014:            fprintf(ficres," %.5e",delti[jk]);
                   11015:            jk++;
                   11016:          }
                   11017:          printf("\n");
                   11018:          fprintf(ficlog,"\n");
                   11019:          fprintf(ficres,"\n");
                   11020:        }
1.126     brouard  11021:       }
                   11022:     }
                   11023:     
                   11024:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11025:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11026:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11027:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11028:     /* # 121 Var(a12)\n\ */
                   11029:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11030:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11031:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11032:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11033:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11034:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11035:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11036:     
                   11037:     
                   11038:     /* Just to have a covariance matrix which will be more understandable
                   11039:        even is we still don't want to manage dictionary of variables
                   11040:     */
                   11041:     for(itimes=1;itimes<=2;itimes++){
                   11042:       jj=0;
                   11043:       for(i=1; i <=nlstate; i++){
1.225     brouard  11044:        for(j=1; j <=nlstate+ndeath; j++){
                   11045:          if(j==i) continue;
                   11046:          for(k=1; k<=ncovmodel;k++){
                   11047:            jj++;
                   11048:            ca[0]= k+'a'-1;ca[1]='\0';
                   11049:            if(itimes==1){
                   11050:              if(mle>=1)
                   11051:                printf("#%1d%1d%d",i,j,k);
                   11052:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11053:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11054:            }else{
                   11055:              if(mle>=1)
                   11056:                printf("%1d%1d%d",i,j,k);
                   11057:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11058:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11059:            }
                   11060:            ll=0;
                   11061:            for(li=1;li <=nlstate; li++){
                   11062:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11063:                if(lj==li) continue;
                   11064:                for(lk=1;lk<=ncovmodel;lk++){
                   11065:                  ll++;
                   11066:                  if(ll<=jj){
                   11067:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11068:                    if(ll<jj){
                   11069:                      if(itimes==1){
                   11070:                        if(mle>=1)
                   11071:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11072:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11073:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11074:                      }else{
                   11075:                        if(mle>=1)
                   11076:                          printf(" %.5e",matcov[jj][ll]); 
                   11077:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11078:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11079:                      }
                   11080:                    }else{
                   11081:                      if(itimes==1){
                   11082:                        if(mle>=1)
                   11083:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11084:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11085:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11086:                      }else{
                   11087:                        if(mle>=1)
                   11088:                          printf(" %.7e",matcov[jj][ll]); 
                   11089:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11090:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11091:                      }
                   11092:                    }
                   11093:                  }
                   11094:                } /* end lk */
                   11095:              } /* end lj */
                   11096:            } /* end li */
                   11097:            if(mle>=1)
                   11098:              printf("\n");
                   11099:            fprintf(ficlog,"\n");
                   11100:            fprintf(ficres,"\n");
                   11101:            numlinepar++;
                   11102:          } /* end k*/
                   11103:        } /*end j */
1.126     brouard  11104:       } /* end i */
                   11105:     } /* end itimes */
                   11106:     
                   11107:     fflush(ficlog);
                   11108:     fflush(ficres);
1.225     brouard  11109:     while(fgets(line, MAXLINE, ficpar)) {
                   11110:       /* If line starts with a # it is a comment */
                   11111:       if (line[0] == '#') {
                   11112:        numlinepar++;
                   11113:        fputs(line,stdout);
                   11114:        fputs(line,ficparo);
                   11115:        fputs(line,ficlog);
                   11116:        continue;
                   11117:       }else
                   11118:        break;
                   11119:     }
                   11120:     
1.209     brouard  11121:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11122:     /*   ungetc(c,ficpar); */
                   11123:     /*   fgets(line, MAXLINE, ficpar); */
                   11124:     /*   fputs(line,stdout); */
                   11125:     /*   fputs(line,ficparo); */
                   11126:     /* } */
                   11127:     /* ungetc(c,ficpar); */
1.126     brouard  11128:     
                   11129:     estepm=0;
1.209     brouard  11130:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11131:       
                   11132:       if (num_filled != 6) {
                   11133:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11134:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11135:        goto end;
                   11136:       }
                   11137:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11138:     }
                   11139:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11140:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11141:     
1.209     brouard  11142:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11143:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11144:     if (fage <= 2) {
                   11145:       bage = ageminpar;
                   11146:       fage = agemaxpar;
                   11147:     }
                   11148:     
                   11149:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11150:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11151:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11152:                
1.186     brouard  11153:     /* Other stuffs, more or less useful */    
1.254     brouard  11154:     while(fgets(line, MAXLINE, ficpar)) {
                   11155:       /* If line starts with a # it is a comment */
                   11156:       if (line[0] == '#') {
                   11157:        numlinepar++;
                   11158:        fputs(line,stdout);
                   11159:        fputs(line,ficparo);
                   11160:        fputs(line,ficlog);
                   11161:        continue;
                   11162:       }else
                   11163:        break;
                   11164:     }
                   11165: 
                   11166:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11167:       
                   11168:       if (num_filled != 7) {
                   11169:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11170:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11171:        goto end;
                   11172:       }
                   11173:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11174:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11175:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11176:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11177:     }
1.254     brouard  11178: 
                   11179:     while(fgets(line, MAXLINE, ficpar)) {
                   11180:       /* If line starts with a # it is a comment */
                   11181:       if (line[0] == '#') {
                   11182:        numlinepar++;
                   11183:        fputs(line,stdout);
                   11184:        fputs(line,ficparo);
                   11185:        fputs(line,ficlog);
                   11186:        continue;
                   11187:       }else
                   11188:        break;
1.126     brouard  11189:     }
                   11190:     
                   11191:     
                   11192:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11193:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11194:     
1.254     brouard  11195:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11196:       if (num_filled != 1) {
                   11197:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11198:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11199:        goto end;
                   11200:       }
                   11201:       printf("pop_based=%d\n",popbased);
                   11202:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11203:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11204:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11205:     }
                   11206:      
1.258     brouard  11207:     /* Results */
                   11208:     nresult=0;
                   11209:     do{
                   11210:       if(!fgets(line, MAXLINE, ficpar)){
                   11211:        endishere=1;
                   11212:        parameterline=14;
                   11213:       }else if (line[0] == '#') {
                   11214:        /* If line starts with a # it is a comment */
1.254     brouard  11215:        numlinepar++;
                   11216:        fputs(line,stdout);
                   11217:        fputs(line,ficparo);
                   11218:        fputs(line,ficlog);
                   11219:        continue;
1.258     brouard  11220:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11221:        parameterline=11;
                   11222:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11223:        parameterline=12;
                   11224:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11225:        parameterline=13;
                   11226:       else{
                   11227:        parameterline=14;
1.254     brouard  11228:       }
1.258     brouard  11229:       switch (parameterline){ 
                   11230:       case 11:
                   11231:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11232:          if (num_filled != 8) {
                   11233:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11234:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11235:            goto end;
                   11236:          }
                   11237:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11238:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11239:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11240:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11241:          /* day and month of proj2 are not used but only year anproj2.*/
                   11242:        }
1.254     brouard  11243:        break;
1.258     brouard  11244:       case 12:
                   11245:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11246:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11247:          if (num_filled != 8) {
1.262   ! brouard  11248:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11249:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  11250:            goto end;
                   11251:          }
                   11252:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11253:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11254:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11255:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11256:          /* day and month of proj2 are not used but only year anproj2.*/
                   11257:        }
1.230     brouard  11258:        break;
1.258     brouard  11259:       case 13:
                   11260:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11261:          if (num_filled == 0){
                   11262:            resultline[0]='\0';
                   11263:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11264:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11265:            break;
                   11266:          } else if (num_filled != 1){
                   11267:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11268:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11269:          }
                   11270:          nresult++; /* Sum of resultlines */
                   11271:          printf("Result %d: result=%s\n",nresult, resultline);
                   11272:          if(nresult > MAXRESULTLINES){
                   11273:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11274:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11275:            goto end;
                   11276:          }
                   11277:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11278:          fprintf(ficparo,"result: %s\n",resultline);
                   11279:          fprintf(ficres,"result: %s\n",resultline);
                   11280:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11281:          break;
1.258     brouard  11282:        case 14: 
1.259     brouard  11283:          if(ncovmodel >2 && nresult==0 ){
                   11284:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11285:            goto end;
                   11286:          }
1.259     brouard  11287:          break;
1.258     brouard  11288:        default:
                   11289:          nresult=1;
                   11290:          decoderesult(".",nresult ); /* No covariate */
                   11291:        }
                   11292:       } /* End switch parameterline */
                   11293:     }while(endishere==0); /* End do */
1.126     brouard  11294:     
1.230     brouard  11295:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11296:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11297:     
                   11298:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11299:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11300:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11301: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11302: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11303:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11304: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11305: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11306:     }else{
1.218     brouard  11307:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11308:     }
                   11309:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11310:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11311:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11312:                
1.225     brouard  11313:     /*------------ free_vector  -------------*/
                   11314:     /*  chdir(path); */
1.220     brouard  11315:                
1.215     brouard  11316:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11317:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11318:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11319:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11320:     free_lvector(num,1,n);
                   11321:     free_vector(agedc,1,n);
                   11322:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11323:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11324:     fclose(ficparo);
                   11325:     fclose(ficres);
1.220     brouard  11326:                
                   11327:                
1.186     brouard  11328:     /* Other results (useful)*/
1.220     brouard  11329:                
                   11330:                
1.126     brouard  11331:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11332:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11333:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11334:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11335:     fclose(ficrespl);
                   11336: 
                   11337:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11338:     /*#include "hpijx.h"*/
                   11339:     hPijx(p, bage, fage);
1.145     brouard  11340:     fclose(ficrespij);
1.227     brouard  11341:     
1.220     brouard  11342:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11343:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11344:     k=1;
1.126     brouard  11345:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11346:     
1.219     brouard  11347:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11348:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11349:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11350:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11351:        for(k=1;k<=ncovcombmax;k++)
                   11352:          probs[i][j][k]=0.;
1.219     brouard  11353:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11354:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11355:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11356:       for(i=1;i<=AGESUP;i++)
                   11357:        for(j=1;j<=nlstate;j++)
                   11358:          for(k=1;k<=ncovcombmax;k++)
                   11359:            mobaverages[i][j][k]=0.;
1.219     brouard  11360:       mobaverage=mobaverages;
                   11361:       if (mobilav!=0) {
1.235     brouard  11362:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11363:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11364:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11365:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11366:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11367:        }
1.219     brouard  11368:       }
                   11369:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11370:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11371:       else if (mobilavproj !=0) {
1.235     brouard  11372:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11373:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11374:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11375:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11376:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11377:        }
1.219     brouard  11378:       }
                   11379:     }/* end if moving average */
1.227     brouard  11380:     
1.126     brouard  11381:     /*---------- Forecasting ------------------*/
                   11382:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11383:     if(prevfcast==1){
                   11384:       /*    if(stepm ==1){*/
1.225     brouard  11385:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11386:     }
1.217     brouard  11387:     if(backcast==1){
1.219     brouard  11388:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11389:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11390:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11391: 
                   11392:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11393: 
                   11394:       bprlim=matrix(1,nlstate,1,nlstate);
                   11395:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11396:       fclose(ficresplb);
                   11397: 
1.222     brouard  11398:       hBijx(p, bage, fage, mobaverage);
                   11399:       fclose(ficrespijb);
1.219     brouard  11400:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11401: 
                   11402:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11403:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11404:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11405:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11406:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11407:     }
1.217     brouard  11408:     
1.186     brouard  11409:  
                   11410:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11411: 
1.215     brouard  11412:     free_ivector(wav,1,imx);
                   11413:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11414:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11415:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11416:                
                   11417:                
1.127     brouard  11418:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11419:                
1.201     brouard  11420:     strcpy(filerese,"E_");
                   11421:     strcat(filerese,fileresu);
1.126     brouard  11422:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11423:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11424:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11425:     }
1.208     brouard  11426:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11427:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11428: 
                   11429:     pstamp(ficreseij);
1.219     brouard  11430:                
1.235     brouard  11431:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11432:     if (cptcovn < 1){i1=1;}
                   11433:     
                   11434:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11435:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11436:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11437:        continue;
1.219     brouard  11438:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11439:       printf("\n#****** ");
1.225     brouard  11440:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11441:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11442:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11443:       }
                   11444:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11445:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11446:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11447:       }
                   11448:       fprintf(ficreseij,"******\n");
1.235     brouard  11449:       printf("******\n");
1.219     brouard  11450:       
                   11451:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11452:       oldm=oldms;savm=savms;
1.235     brouard  11453:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11454:       
1.219     brouard  11455:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11456:     }
                   11457:     fclose(ficreseij);
1.208     brouard  11458:     printf("done evsij\n");fflush(stdout);
                   11459:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11460:                
1.227     brouard  11461:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11462:                
                   11463:                
1.201     brouard  11464:     strcpy(filerest,"T_");
                   11465:     strcat(filerest,fileresu);
1.127     brouard  11466:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11467:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11468:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11469:     }
1.208     brouard  11470:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11471:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11472:                
1.126     brouard  11473: 
1.201     brouard  11474:     strcpy(fileresstde,"STDE_");
                   11475:     strcat(fileresstde,fileresu);
1.126     brouard  11476:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11477:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11478:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11479:     }
1.227     brouard  11480:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11481:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11482: 
1.201     brouard  11483:     strcpy(filerescve,"CVE_");
                   11484:     strcat(filerescve,fileresu);
1.126     brouard  11485:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11486:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11487:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11488:     }
1.227     brouard  11489:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11490:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11491: 
1.201     brouard  11492:     strcpy(fileresv,"V_");
                   11493:     strcat(fileresv,fileresu);
1.126     brouard  11494:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11495:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11496:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11497:     }
1.227     brouard  11498:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11499:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11500: 
1.145     brouard  11501:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11502:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11503:           
1.235     brouard  11504:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11505:     if (cptcovn < 1){i1=1;}
                   11506:     
                   11507:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11508:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11509:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11510:        continue;
1.242     brouard  11511:       printf("\n#****** Result for:");
                   11512:       fprintf(ficrest,"\n#****** Result for:");
                   11513:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11514:       for(j=1;j<=cptcoveff;j++){ 
                   11515:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11516:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11517:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11518:       }
1.235     brouard  11519:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11520:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11521:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11522:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11523:       }        
1.208     brouard  11524:       fprintf(ficrest,"******\n");
1.227     brouard  11525:       fprintf(ficlog,"******\n");
                   11526:       printf("******\n");
1.208     brouard  11527:       
                   11528:       fprintf(ficresstdeij,"\n#****** ");
                   11529:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11530:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11531:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11532:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11533:       }
1.235     brouard  11534:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11535:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11536:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11537:       }        
1.208     brouard  11538:       fprintf(ficresstdeij,"******\n");
                   11539:       fprintf(ficrescveij,"******\n");
                   11540:       
                   11541:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11542:       /* pstamp(ficresvij); */
1.225     brouard  11543:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11544:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11545:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11546:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11547:       }        
1.208     brouard  11548:       fprintf(ficresvij,"******\n");
                   11549:       
                   11550:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11551:       oldm=oldms;savm=savms;
1.235     brouard  11552:       printf(" cvevsij ");
                   11553:       fprintf(ficlog, " cvevsij ");
                   11554:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11555:       printf(" end cvevsij \n ");
                   11556:       fprintf(ficlog, " end cvevsij \n ");
                   11557:       
                   11558:       /*
                   11559:        */
                   11560:       /* goto endfree; */
                   11561:       
                   11562:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11563:       pstamp(ficrest);
                   11564:       
                   11565:       
                   11566:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11567:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11568:        cptcod= 0; /* To be deleted */
                   11569:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11570:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11571:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11572:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11573:        if(vpopbased==1)
                   11574:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11575:        else
                   11576:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11577:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11578:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11579:        fprintf(ficrest,"\n");
                   11580:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11581:        epj=vector(1,nlstate+1);
                   11582:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11583:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11584:        for(age=bage; age <=fage ;age++){
1.235     brouard  11585:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11586:          if (vpopbased==1) {
                   11587:            if(mobilav ==0){
                   11588:              for(i=1; i<=nlstate;i++)
                   11589:                prlim[i][i]=probs[(int)age][i][k];
                   11590:            }else{ /* mobilav */ 
                   11591:              for(i=1; i<=nlstate;i++)
                   11592:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11593:            }
                   11594:          }
1.219     brouard  11595:          
1.227     brouard  11596:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11597:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11598:          /* printf(" age %4.0f ",age); */
                   11599:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11600:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11601:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11602:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11603:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11604:            }
                   11605:            epj[nlstate+1] +=epj[j];
                   11606:          }
                   11607:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11608:          
1.227     brouard  11609:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11610:            for(j=1;j <=nlstate;j++)
                   11611:              vepp += vareij[i][j][(int)age];
                   11612:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11613:          for(j=1;j <=nlstate;j++){
                   11614:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11615:          }
                   11616:          fprintf(ficrest,"\n");
                   11617:        }
1.208     brouard  11618:       } /* End vpopbased */
                   11619:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11620:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11621:       free_vector(epj,1,nlstate+1);
1.235     brouard  11622:       printf("done selection\n");fflush(stdout);
                   11623:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11624:       
1.145     brouard  11625:       /*}*/
1.235     brouard  11626:     } /* End k selection */
1.227     brouard  11627: 
                   11628:     printf("done State-specific expectancies\n");fflush(stdout);
                   11629:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11630: 
1.126     brouard  11631:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11632:     
1.201     brouard  11633:     strcpy(fileresvpl,"VPL_");
                   11634:     strcat(fileresvpl,fileresu);
1.126     brouard  11635:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11636:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11637:       exit(0);
                   11638:     }
1.208     brouard  11639:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11640:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11641:     
1.145     brouard  11642:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11643:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11644:     
1.235     brouard  11645:     i1=pow(2,cptcoveff);
                   11646:     if (cptcovn < 1){i1=1;}
                   11647: 
                   11648:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11649:     for(k=1; k<=i1;k++){
1.253     brouard  11650:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11651:        continue;
1.227     brouard  11652:       fprintf(ficresvpl,"\n#****** ");
                   11653:       printf("\n#****** ");
                   11654:       fprintf(ficlog,"\n#****** ");
                   11655:       for(j=1;j<=cptcoveff;j++) {
                   11656:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11657:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11658:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11659:       }
1.235     brouard  11660:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11661:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11662:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11663:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11664:       }        
1.227     brouard  11665:       fprintf(ficresvpl,"******\n");
                   11666:       printf("******\n");
                   11667:       fprintf(ficlog,"******\n");
                   11668:       
                   11669:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11670:       oldm=oldms;savm=savms;
1.235     brouard  11671:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11672:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11673:       /*}*/
1.126     brouard  11674:     }
1.227     brouard  11675:     
1.126     brouard  11676:     fclose(ficresvpl);
1.208     brouard  11677:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11678:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11679:     
                   11680:     free_vector(weight,1,n);
                   11681:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11682:     free_imatrix(s,1,maxwav+1,1,n);
                   11683:     free_matrix(anint,1,maxwav,1,n); 
                   11684:     free_matrix(mint,1,maxwav,1,n);
                   11685:     free_ivector(cod,1,n);
                   11686:     free_ivector(tab,1,NCOVMAX);
                   11687:     fclose(ficresstdeij);
                   11688:     fclose(ficrescveij);
                   11689:     fclose(ficresvij);
                   11690:     fclose(ficrest);
                   11691:     fclose(ficpar);
                   11692:     
                   11693:     
1.126     brouard  11694:     /*---------- End : free ----------------*/
1.219     brouard  11695:     if (mobilav!=0 ||mobilavproj !=0)
                   11696:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11697:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11698:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11699:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11700:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11701:   /* endfree:*/
                   11702:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11703:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11704:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11705:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11706:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11707:   free_matrix(coqvar,1,maxwav,1,n);
                   11708:   free_matrix(covar,0,NCOVMAX,1,n);
                   11709:   free_matrix(matcov,1,npar,1,npar);
                   11710:   free_matrix(hess,1,npar,1,npar);
                   11711:   /*free_vector(delti,1,npar);*/
                   11712:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11713:   free_matrix(agev,1,maxwav,1,imx);
                   11714:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11715:   
                   11716:   free_ivector(ncodemax,1,NCOVMAX);
                   11717:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11718:   free_ivector(Dummy,-1,NCOVMAX);
                   11719:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11720:   free_ivector(DummyV,1,NCOVMAX);
                   11721:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11722:   free_ivector(Typevar,-1,NCOVMAX);
                   11723:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11724:   free_ivector(TvarsQ,1,NCOVMAX);
                   11725:   free_ivector(TvarsQind,1,NCOVMAX);
                   11726:   free_ivector(TvarsD,1,NCOVMAX);
                   11727:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11728:   free_ivector(TvarFD,1,NCOVMAX);
                   11729:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11730:   free_ivector(TvarF,1,NCOVMAX);
                   11731:   free_ivector(TvarFind,1,NCOVMAX);
                   11732:   free_ivector(TvarV,1,NCOVMAX);
                   11733:   free_ivector(TvarVind,1,NCOVMAX);
                   11734:   free_ivector(TvarA,1,NCOVMAX);
                   11735:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11736:   free_ivector(TvarFQ,1,NCOVMAX);
                   11737:   free_ivector(TvarFQind,1,NCOVMAX);
                   11738:   free_ivector(TvarVD,1,NCOVMAX);
                   11739:   free_ivector(TvarVDind,1,NCOVMAX);
                   11740:   free_ivector(TvarVQ,1,NCOVMAX);
                   11741:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11742:   free_ivector(Tvarsel,1,NCOVMAX);
                   11743:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11744:   free_ivector(Tposprod,1,NCOVMAX);
                   11745:   free_ivector(Tprod,1,NCOVMAX);
                   11746:   free_ivector(Tvaraff,1,NCOVMAX);
                   11747:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11748:   free_ivector(Tage,1,NCOVMAX);
                   11749:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11750:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11751:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11752:   
                   11753:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11754:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11755:   fflush(fichtm);
                   11756:   fflush(ficgp);
                   11757:   
1.227     brouard  11758:   
1.126     brouard  11759:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11760:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11761:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11762:   }else{
                   11763:     printf("End of Imach\n");
                   11764:     fprintf(ficlog,"End of Imach\n");
                   11765:   }
                   11766:   printf("See log file on %s\n",filelog);
                   11767:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11768:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11769:   rend_time = time(NULL);  
                   11770:   end_time = *localtime(&rend_time);
                   11771:   /* tml = *localtime(&end_time.tm_sec); */
                   11772:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11773:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11774:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11775:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11776:   
1.157     brouard  11777:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11778:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11779:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11780:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11781: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11782:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11783:   fclose(fichtm);
                   11784:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11785:   fclose(fichtmcov);
                   11786:   fclose(ficgp);
                   11787:   fclose(ficlog);
                   11788:   /*------ End -----------*/
1.227     brouard  11789:   
                   11790:   
                   11791:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11792: #ifdef WIN32
1.227     brouard  11793:   if (_chdir(pathcd) != 0)
                   11794:     printf("Can't move to directory %s!\n",path);
                   11795:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11796: #else
1.227     brouard  11797:     if(chdir(pathcd) != 0)
                   11798:       printf("Can't move to directory %s!\n", path);
                   11799:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11800: #endif 
1.126     brouard  11801:     printf("Current directory %s!\n",pathcd);
                   11802:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11803:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11804: #ifdef _WIN32
1.126     brouard  11805:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11806: #endif
                   11807:   if(!stat(plotcmd,&info)){
1.158     brouard  11808:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11809:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11810:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11811:     }else
                   11812:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11813: #ifdef __unix
1.126     brouard  11814:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11815:     if(!stat(plotcmd,&info)){
1.158     brouard  11816:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11817:     }else
                   11818:       strcpy(pplotcmd,plotcmd);
                   11819: #endif
                   11820:   }else
                   11821:     strcpy(pplotcmd,plotcmd);
                   11822:   
                   11823:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11824:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11825:   
1.126     brouard  11826:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11827:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11828:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11829:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11830:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11831:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11832:   }
1.158     brouard  11833:   printf(" Successful, please wait...");
1.126     brouard  11834:   while (z[0] != 'q') {
                   11835:     /* chdir(path); */
1.154     brouard  11836:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11837:     scanf("%s",z);
                   11838: /*     if (z[0] == 'c') system("./imach"); */
                   11839:     if (z[0] == 'e') {
1.158     brouard  11840: #ifdef __APPLE__
1.152     brouard  11841:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11842: #elif __linux
                   11843:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11844: #else
1.152     brouard  11845:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11846: #endif
                   11847:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11848:       system(pplotcmd);
1.126     brouard  11849:     }
                   11850:     else if (z[0] == 'g') system(plotcmd);
                   11851:     else if (z[0] == 'q') exit(0);
                   11852:   }
1.227     brouard  11853: end:
1.126     brouard  11854:   while (z[0] != 'q') {
1.195     brouard  11855:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11856:     scanf("%s",z);
                   11857:   }
                   11858: }

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