Annotation of imach/src/imach.c, revision 1.264

1.264   ! brouard     1: /* $Id: imach.c,v 1.263 2017/04/24 15:23:15 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.264   ! brouard     4:   Revision 1.263  2017/04/24 15:23:15  brouard
        !             5:   Summary: to save
        !             6: 
1.263     brouard     7:   Revision 1.262  2017/04/18 16:48:12  brouard
                      8:   *** empty log message ***
                      9: 
1.262     brouard    10:   Revision 1.261  2017/04/05 10:14:09  brouard
                     11:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     12: 
1.261     brouard    13:   Revision 1.260  2017/04/04 17:46:59  brouard
                     14:   Summary: Gnuplot indexations fixed (humm)
                     15: 
1.260     brouard    16:   Revision 1.259  2017/04/04 13:01:16  brouard
                     17:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     18: 
1.259     brouard    19:   Revision 1.258  2017/04/03 10:17:47  brouard
                     20:   Summary: Version 0.99r12
                     21: 
                     22:   Some cleanings, conformed with updated documentation.
                     23: 
1.258     brouard    24:   Revision 1.257  2017/03/29 16:53:30  brouard
                     25:   Summary: Temp
                     26: 
1.257     brouard    27:   Revision 1.256  2017/03/27 05:50:23  brouard
                     28:   Summary: Temporary
                     29: 
1.256     brouard    30:   Revision 1.255  2017/03/08 16:02:28  brouard
                     31:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     32: 
1.255     brouard    33:   Revision 1.254  2017/03/08 07:13:00  brouard
                     34:   Summary: Fixing data parameter line
                     35: 
1.254     brouard    36:   Revision 1.253  2016/12/15 11:59:41  brouard
                     37:   Summary: 0.99 in progress
                     38: 
1.253     brouard    39:   Revision 1.252  2016/09/15 21:15:37  brouard
                     40:   *** empty log message ***
                     41: 
1.252     brouard    42:   Revision 1.251  2016/09/15 15:01:13  brouard
                     43:   Summary: not working
                     44: 
1.251     brouard    45:   Revision 1.250  2016/09/08 16:07:27  brouard
                     46:   Summary: continue
                     47: 
1.250     brouard    48:   Revision 1.249  2016/09/07 17:14:18  brouard
                     49:   Summary: Starting values from frequencies
                     50: 
1.249     brouard    51:   Revision 1.248  2016/09/07 14:10:18  brouard
                     52:   *** empty log message ***
                     53: 
1.248     brouard    54:   Revision 1.247  2016/09/02 11:11:21  brouard
                     55:   *** empty log message ***
                     56: 
1.247     brouard    57:   Revision 1.246  2016/09/02 08:49:22  brouard
                     58:   *** empty log message ***
                     59: 
1.246     brouard    60:   Revision 1.245  2016/09/02 07:25:01  brouard
                     61:   *** empty log message ***
                     62: 
1.245     brouard    63:   Revision 1.244  2016/09/02 07:17:34  brouard
                     64:   *** empty log message ***
                     65: 
1.244     brouard    66:   Revision 1.243  2016/09/02 06:45:35  brouard
                     67:   *** empty log message ***
                     68: 
1.243     brouard    69:   Revision 1.242  2016/08/30 15:01:20  brouard
                     70:   Summary: Fixing a lots
                     71: 
1.242     brouard    72:   Revision 1.241  2016/08/29 17:17:25  brouard
                     73:   Summary: gnuplot problem in Back projection to fix
                     74: 
1.241     brouard    75:   Revision 1.240  2016/08/29 07:53:18  brouard
                     76:   Summary: Better
                     77: 
1.240     brouard    78:   Revision 1.239  2016/08/26 15:51:03  brouard
                     79:   Summary: Improvement in Powell output in order to copy and paste
                     80: 
                     81:   Author:
                     82: 
1.239     brouard    83:   Revision 1.238  2016/08/26 14:23:35  brouard
                     84:   Summary: Starting tests of 0.99
                     85: 
1.238     brouard    86:   Revision 1.237  2016/08/26 09:20:19  brouard
                     87:   Summary: to valgrind
                     88: 
1.237     brouard    89:   Revision 1.236  2016/08/25 10:50:18  brouard
                     90:   *** empty log message ***
                     91: 
1.236     brouard    92:   Revision 1.235  2016/08/25 06:59:23  brouard
                     93:   *** empty log message ***
                     94: 
1.235     brouard    95:   Revision 1.234  2016/08/23 16:51:20  brouard
                     96:   *** empty log message ***
                     97: 
1.234     brouard    98:   Revision 1.233  2016/08/23 07:40:50  brouard
                     99:   Summary: not working
                    100: 
1.233     brouard   101:   Revision 1.232  2016/08/22 14:20:21  brouard
                    102:   Summary: not working
                    103: 
1.232     brouard   104:   Revision 1.231  2016/08/22 07:17:15  brouard
                    105:   Summary: not working
                    106: 
1.231     brouard   107:   Revision 1.230  2016/08/22 06:55:53  brouard
                    108:   Summary: Not working
                    109: 
1.230     brouard   110:   Revision 1.229  2016/07/23 09:45:53  brouard
                    111:   Summary: Completing for func too
                    112: 
1.229     brouard   113:   Revision 1.228  2016/07/22 17:45:30  brouard
                    114:   Summary: Fixing some arrays, still debugging
                    115: 
1.227     brouard   116:   Revision 1.226  2016/07/12 18:42:34  brouard
                    117:   Summary: temp
                    118: 
1.226     brouard   119:   Revision 1.225  2016/07/12 08:40:03  brouard
                    120:   Summary: saving but not running
                    121: 
1.225     brouard   122:   Revision 1.224  2016/07/01 13:16:01  brouard
                    123:   Summary: Fixes
                    124: 
1.224     brouard   125:   Revision 1.223  2016/02/19 09:23:35  brouard
                    126:   Summary: temporary
                    127: 
1.223     brouard   128:   Revision 1.222  2016/02/17 08:14:50  brouard
                    129:   Summary: Probably last 0.98 stable version 0.98r6
                    130: 
1.222     brouard   131:   Revision 1.221  2016/02/15 23:35:36  brouard
                    132:   Summary: minor bug
                    133: 
1.220     brouard   134:   Revision 1.219  2016/02/15 00:48:12  brouard
                    135:   *** empty log message ***
                    136: 
1.219     brouard   137:   Revision 1.218  2016/02/12 11:29:23  brouard
                    138:   Summary: 0.99 Back projections
                    139: 
1.218     brouard   140:   Revision 1.217  2015/12/23 17:18:31  brouard
                    141:   Summary: Experimental backcast
                    142: 
1.217     brouard   143:   Revision 1.216  2015/12/18 17:32:11  brouard
                    144:   Summary: 0.98r4 Warning and status=-2
                    145: 
                    146:   Version 0.98r4 is now:
                    147:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    148:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    149:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    150: 
1.216     brouard   151:   Revision 1.215  2015/12/16 08:52:24  brouard
                    152:   Summary: 0.98r4 working
                    153: 
1.215     brouard   154:   Revision 1.214  2015/12/16 06:57:54  brouard
                    155:   Summary: temporary not working
                    156: 
1.214     brouard   157:   Revision 1.213  2015/12/11 18:22:17  brouard
                    158:   Summary: 0.98r4
                    159: 
1.213     brouard   160:   Revision 1.212  2015/11/21 12:47:24  brouard
                    161:   Summary: minor typo
                    162: 
1.212     brouard   163:   Revision 1.211  2015/11/21 12:41:11  brouard
                    164:   Summary: 0.98r3 with some graph of projected cross-sectional
                    165: 
                    166:   Author: Nicolas Brouard
                    167: 
1.211     brouard   168:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   169:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   170:   Summary: Adding ftolpl parameter
                    171:   Author: N Brouard
                    172: 
                    173:   We had difficulties to get smoothed confidence intervals. It was due
                    174:   to the period prevalence which wasn't computed accurately. The inner
                    175:   parameter ftolpl is now an outer parameter of the .imach parameter
                    176:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    177:   computation are long.
                    178: 
1.209     brouard   179:   Revision 1.208  2015/11/17 14:31:57  brouard
                    180:   Summary: temporary
                    181: 
1.208     brouard   182:   Revision 1.207  2015/10/27 17:36:57  brouard
                    183:   *** empty log message ***
                    184: 
1.207     brouard   185:   Revision 1.206  2015/10/24 07:14:11  brouard
                    186:   *** empty log message ***
                    187: 
1.206     brouard   188:   Revision 1.205  2015/10/23 15:50:53  brouard
                    189:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    190: 
1.205     brouard   191:   Revision 1.204  2015/10/01 16:20:26  brouard
                    192:   Summary: Some new graphs of contribution to likelihood
                    193: 
1.204     brouard   194:   Revision 1.203  2015/09/30 17:45:14  brouard
                    195:   Summary: looking at better estimation of the hessian
                    196: 
                    197:   Also a better criteria for convergence to the period prevalence And
                    198:   therefore adding the number of years needed to converge. (The
                    199:   prevalence in any alive state shold sum to one
                    200: 
1.203     brouard   201:   Revision 1.202  2015/09/22 19:45:16  brouard
                    202:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    203: 
1.202     brouard   204:   Revision 1.201  2015/09/15 17:34:58  brouard
                    205:   Summary: 0.98r0
                    206: 
                    207:   - Some new graphs like suvival functions
                    208:   - Some bugs fixed like model=1+age+V2.
                    209: 
1.201     brouard   210:   Revision 1.200  2015/09/09 16:53:55  brouard
                    211:   Summary: Big bug thanks to Flavia
                    212: 
                    213:   Even model=1+age+V2. did not work anymore
                    214: 
1.200     brouard   215:   Revision 1.199  2015/09/07 14:09:23  brouard
                    216:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    217: 
1.199     brouard   218:   Revision 1.198  2015/09/03 07:14:39  brouard
                    219:   Summary: 0.98q5 Flavia
                    220: 
1.198     brouard   221:   Revision 1.197  2015/09/01 18:24:39  brouard
                    222:   *** empty log message ***
                    223: 
1.197     brouard   224:   Revision 1.196  2015/08/18 23:17:52  brouard
                    225:   Summary: 0.98q5
                    226: 
1.196     brouard   227:   Revision 1.195  2015/08/18 16:28:39  brouard
                    228:   Summary: Adding a hack for testing purpose
                    229: 
                    230:   After reading the title, ftol and model lines, if the comment line has
                    231:   a q, starting with #q, the answer at the end of the run is quit. It
                    232:   permits to run test files in batch with ctest. The former workaround was
                    233:   $ echo q | imach foo.imach
                    234: 
1.195     brouard   235:   Revision 1.194  2015/08/18 13:32:00  brouard
                    236:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    237: 
1.194     brouard   238:   Revision 1.193  2015/08/04 07:17:42  brouard
                    239:   Summary: 0.98q4
                    240: 
1.193     brouard   241:   Revision 1.192  2015/07/16 16:49:02  brouard
                    242:   Summary: Fixing some outputs
                    243: 
1.192     brouard   244:   Revision 1.191  2015/07/14 10:00:33  brouard
                    245:   Summary: Some fixes
                    246: 
1.191     brouard   247:   Revision 1.190  2015/05/05 08:51:13  brouard
                    248:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    249: 
                    250:   Fix 1+age+.
                    251: 
1.190     brouard   252:   Revision 1.189  2015/04/30 14:45:16  brouard
                    253:   Summary: 0.98q2
                    254: 
1.189     brouard   255:   Revision 1.188  2015/04/30 08:27:53  brouard
                    256:   *** empty log message ***
                    257: 
1.188     brouard   258:   Revision 1.187  2015/04/29 09:11:15  brouard
                    259:   *** empty log message ***
                    260: 
1.187     brouard   261:   Revision 1.186  2015/04/23 12:01:52  brouard
                    262:   Summary: V1*age is working now, version 0.98q1
                    263: 
                    264:   Some codes had been disabled in order to simplify and Vn*age was
                    265:   working in the optimization phase, ie, giving correct MLE parameters,
                    266:   but, as usual, outputs were not correct and program core dumped.
                    267: 
1.186     brouard   268:   Revision 1.185  2015/03/11 13:26:42  brouard
                    269:   Summary: Inclusion of compile and links command line for Intel Compiler
                    270: 
1.185     brouard   271:   Revision 1.184  2015/03/11 11:52:39  brouard
                    272:   Summary: Back from Windows 8. Intel Compiler
                    273: 
1.184     brouard   274:   Revision 1.183  2015/03/10 20:34:32  brouard
                    275:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    276: 
                    277:   We use directest instead of original Powell test; probably no
                    278:   incidence on the results, but better justifications;
                    279:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    280:   wrong results.
                    281: 
1.183     brouard   282:   Revision 1.182  2015/02/12 08:19:57  brouard
                    283:   Summary: Trying to keep directest which seems simpler and more general
                    284:   Author: Nicolas Brouard
                    285: 
1.182     brouard   286:   Revision 1.181  2015/02/11 23:22:24  brouard
                    287:   Summary: Comments on Powell added
                    288: 
                    289:   Author:
                    290: 
1.181     brouard   291:   Revision 1.180  2015/02/11 17:33:45  brouard
                    292:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    293: 
1.180     brouard   294:   Revision 1.179  2015/01/04 09:57:06  brouard
                    295:   Summary: back to OS/X
                    296: 
1.179     brouard   297:   Revision 1.178  2015/01/04 09:35:48  brouard
                    298:   *** empty log message ***
                    299: 
1.178     brouard   300:   Revision 1.177  2015/01/03 18:40:56  brouard
                    301:   Summary: Still testing ilc32 on OSX
                    302: 
1.177     brouard   303:   Revision 1.176  2015/01/03 16:45:04  brouard
                    304:   *** empty log message ***
                    305: 
1.176     brouard   306:   Revision 1.175  2015/01/03 16:33:42  brouard
                    307:   *** empty log message ***
                    308: 
1.175     brouard   309:   Revision 1.174  2015/01/03 16:15:49  brouard
                    310:   Summary: Still in cross-compilation
                    311: 
1.174     brouard   312:   Revision 1.173  2015/01/03 12:06:26  brouard
                    313:   Summary: trying to detect cross-compilation
                    314: 
1.173     brouard   315:   Revision 1.172  2014/12/27 12:07:47  brouard
                    316:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    317: 
1.172     brouard   318:   Revision 1.171  2014/12/23 13:26:59  brouard
                    319:   Summary: Back from Visual C
                    320: 
                    321:   Still problem with utsname.h on Windows
                    322: 
1.171     brouard   323:   Revision 1.170  2014/12/23 11:17:12  brouard
                    324:   Summary: Cleaning some \%% back to %%
                    325: 
                    326:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    327: 
1.170     brouard   328:   Revision 1.169  2014/12/22 23:08:31  brouard
                    329:   Summary: 0.98p
                    330: 
                    331:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    332: 
1.169     brouard   333:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   334:   Summary: update
1.169     brouard   335: 
1.168     brouard   336:   Revision 1.167  2014/12/22 13:50:56  brouard
                    337:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    338: 
                    339:   Testing on Linux 64
                    340: 
1.167     brouard   341:   Revision 1.166  2014/12/22 11:40:47  brouard
                    342:   *** empty log message ***
                    343: 
1.166     brouard   344:   Revision 1.165  2014/12/16 11:20:36  brouard
                    345:   Summary: After compiling on Visual C
                    346: 
                    347:   * imach.c (Module): Merging 1.61 to 1.162
                    348: 
1.165     brouard   349:   Revision 1.164  2014/12/16 10:52:11  brouard
                    350:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    351: 
                    352:   * imach.c (Module): Merging 1.61 to 1.162
                    353: 
1.164     brouard   354:   Revision 1.163  2014/12/16 10:30:11  brouard
                    355:   * imach.c (Module): Merging 1.61 to 1.162
                    356: 
1.163     brouard   357:   Revision 1.162  2014/09/25 11:43:39  brouard
                    358:   Summary: temporary backup 0.99!
                    359: 
1.162     brouard   360:   Revision 1.1  2014/09/16 11:06:58  brouard
                    361:   Summary: With some code (wrong) for nlopt
                    362: 
                    363:   Author:
                    364: 
                    365:   Revision 1.161  2014/09/15 20:41:41  brouard
                    366:   Summary: Problem with macro SQR on Intel compiler
                    367: 
1.161     brouard   368:   Revision 1.160  2014/09/02 09:24:05  brouard
                    369:   *** empty log message ***
                    370: 
1.160     brouard   371:   Revision 1.159  2014/09/01 10:34:10  brouard
                    372:   Summary: WIN32
                    373:   Author: Brouard
                    374: 
1.159     brouard   375:   Revision 1.158  2014/08/27 17:11:51  brouard
                    376:   *** empty log message ***
                    377: 
1.158     brouard   378:   Revision 1.157  2014/08/27 16:26:55  brouard
                    379:   Summary: Preparing windows Visual studio version
                    380:   Author: Brouard
                    381: 
                    382:   In order to compile on Visual studio, time.h is now correct and time_t
                    383:   and tm struct should be used. difftime should be used but sometimes I
                    384:   just make the differences in raw time format (time(&now).
                    385:   Trying to suppress #ifdef LINUX
                    386:   Add xdg-open for __linux in order to open default browser.
                    387: 
1.157     brouard   388:   Revision 1.156  2014/08/25 20:10:10  brouard
                    389:   *** empty log message ***
                    390: 
1.156     brouard   391:   Revision 1.155  2014/08/25 18:32:34  brouard
                    392:   Summary: New compile, minor changes
                    393:   Author: Brouard
                    394: 
1.155     brouard   395:   Revision 1.154  2014/06/20 17:32:08  brouard
                    396:   Summary: Outputs now all graphs of convergence to period prevalence
                    397: 
1.154     brouard   398:   Revision 1.153  2014/06/20 16:45:46  brouard
                    399:   Summary: If 3 live state, convergence to period prevalence on same graph
                    400:   Author: Brouard
                    401: 
1.153     brouard   402:   Revision 1.152  2014/06/18 17:54:09  brouard
                    403:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    404: 
1.152     brouard   405:   Revision 1.151  2014/06/18 16:43:30  brouard
                    406:   *** empty log message ***
                    407: 
1.151     brouard   408:   Revision 1.150  2014/06/18 16:42:35  brouard
                    409:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    410:   Author: brouard
                    411: 
1.150     brouard   412:   Revision 1.149  2014/06/18 15:51:14  brouard
                    413:   Summary: Some fixes in parameter files errors
                    414:   Author: Nicolas Brouard
                    415: 
1.149     brouard   416:   Revision 1.148  2014/06/17 17:38:48  brouard
                    417:   Summary: Nothing new
                    418:   Author: Brouard
                    419: 
                    420:   Just a new packaging for OS/X version 0.98nS
                    421: 
1.148     brouard   422:   Revision 1.147  2014/06/16 10:33:11  brouard
                    423:   *** empty log message ***
                    424: 
1.147     brouard   425:   Revision 1.146  2014/06/16 10:20:28  brouard
                    426:   Summary: Merge
                    427:   Author: Brouard
                    428: 
                    429:   Merge, before building revised version.
                    430: 
1.146     brouard   431:   Revision 1.145  2014/06/10 21:23:15  brouard
                    432:   Summary: Debugging with valgrind
                    433:   Author: Nicolas Brouard
                    434: 
                    435:   Lot of changes in order to output the results with some covariates
                    436:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    437:   improve the code.
                    438:   No more memory valgrind error but a lot has to be done in order to
                    439:   continue the work of splitting the code into subroutines.
                    440:   Also, decodemodel has been improved. Tricode is still not
                    441:   optimal. nbcode should be improved. Documentation has been added in
                    442:   the source code.
                    443: 
1.144     brouard   444:   Revision 1.143  2014/01/26 09:45:38  brouard
                    445:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    446: 
                    447:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    448:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    449: 
1.143     brouard   450:   Revision 1.142  2014/01/26 03:57:36  brouard
                    451:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    452: 
                    453:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    454: 
1.142     brouard   455:   Revision 1.141  2014/01/26 02:42:01  brouard
                    456:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    457: 
1.141     brouard   458:   Revision 1.140  2011/09/02 10:37:54  brouard
                    459:   Summary: times.h is ok with mingw32 now.
                    460: 
1.140     brouard   461:   Revision 1.139  2010/06/14 07:50:17  brouard
                    462:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    463:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    464: 
1.139     brouard   465:   Revision 1.138  2010/04/30 18:19:40  brouard
                    466:   *** empty log message ***
                    467: 
1.138     brouard   468:   Revision 1.137  2010/04/29 18:11:38  brouard
                    469:   (Module): Checking covariates for more complex models
                    470:   than V1+V2. A lot of change to be done. Unstable.
                    471: 
1.137     brouard   472:   Revision 1.136  2010/04/26 20:30:53  brouard
                    473:   (Module): merging some libgsl code. Fixing computation
                    474:   of likelione (using inter/intrapolation if mle = 0) in order to
                    475:   get same likelihood as if mle=1.
                    476:   Some cleaning of code and comments added.
                    477: 
1.136     brouard   478:   Revision 1.135  2009/10/29 15:33:14  brouard
                    479:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    480: 
1.135     brouard   481:   Revision 1.134  2009/10/29 13:18:53  brouard
                    482:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    483: 
1.134     brouard   484:   Revision 1.133  2009/07/06 10:21:25  brouard
                    485:   just nforces
                    486: 
1.133     brouard   487:   Revision 1.132  2009/07/06 08:22:05  brouard
                    488:   Many tings
                    489: 
1.132     brouard   490:   Revision 1.131  2009/06/20 16:22:47  brouard
                    491:   Some dimensions resccaled
                    492: 
1.131     brouard   493:   Revision 1.130  2009/05/26 06:44:34  brouard
                    494:   (Module): Max Covariate is now set to 20 instead of 8. A
                    495:   lot of cleaning with variables initialized to 0. Trying to make
                    496:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    497: 
1.130     brouard   498:   Revision 1.129  2007/08/31 13:49:27  lievre
                    499:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    500: 
1.129     lievre    501:   Revision 1.128  2006/06/30 13:02:05  brouard
                    502:   (Module): Clarifications on computing e.j
                    503: 
1.128     brouard   504:   Revision 1.127  2006/04/28 18:11:50  brouard
                    505:   (Module): Yes the sum of survivors was wrong since
                    506:   imach-114 because nhstepm was no more computed in the age
                    507:   loop. Now we define nhstepma in the age loop.
                    508:   (Module): In order to speed up (in case of numerous covariates) we
                    509:   compute health expectancies (without variances) in a first step
                    510:   and then all the health expectancies with variances or standard
                    511:   deviation (needs data from the Hessian matrices) which slows the
                    512:   computation.
                    513:   In the future we should be able to stop the program is only health
                    514:   expectancies and graph are needed without standard deviations.
                    515: 
1.127     brouard   516:   Revision 1.126  2006/04/28 17:23:28  brouard
                    517:   (Module): Yes the sum of survivors was wrong since
                    518:   imach-114 because nhstepm was no more computed in the age
                    519:   loop. Now we define nhstepma in the age loop.
                    520:   Version 0.98h
                    521: 
1.126     brouard   522:   Revision 1.125  2006/04/04 15:20:31  lievre
                    523:   Errors in calculation of health expectancies. Age was not initialized.
                    524:   Forecasting file added.
                    525: 
                    526:   Revision 1.124  2006/03/22 17:13:53  lievre
                    527:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    528:   The log-likelihood is printed in the log file
                    529: 
                    530:   Revision 1.123  2006/03/20 10:52:43  brouard
                    531:   * imach.c (Module): <title> changed, corresponds to .htm file
                    532:   name. <head> headers where missing.
                    533: 
                    534:   * imach.c (Module): Weights can have a decimal point as for
                    535:   English (a comma might work with a correct LC_NUMERIC environment,
                    536:   otherwise the weight is truncated).
                    537:   Modification of warning when the covariates values are not 0 or
                    538:   1.
                    539:   Version 0.98g
                    540: 
                    541:   Revision 1.122  2006/03/20 09:45:41  brouard
                    542:   (Module): Weights can have a decimal point as for
                    543:   English (a comma might work with a correct LC_NUMERIC environment,
                    544:   otherwise the weight is truncated).
                    545:   Modification of warning when the covariates values are not 0 or
                    546:   1.
                    547:   Version 0.98g
                    548: 
                    549:   Revision 1.121  2006/03/16 17:45:01  lievre
                    550:   * imach.c (Module): Comments concerning covariates added
                    551: 
                    552:   * imach.c (Module): refinements in the computation of lli if
                    553:   status=-2 in order to have more reliable computation if stepm is
                    554:   not 1 month. Version 0.98f
                    555: 
                    556:   Revision 1.120  2006/03/16 15:10:38  lievre
                    557:   (Module): refinements in the computation of lli if
                    558:   status=-2 in order to have more reliable computation if stepm is
                    559:   not 1 month. Version 0.98f
                    560: 
                    561:   Revision 1.119  2006/03/15 17:42:26  brouard
                    562:   (Module): Bug if status = -2, the loglikelihood was
                    563:   computed as likelihood omitting the logarithm. Version O.98e
                    564: 
                    565:   Revision 1.118  2006/03/14 18:20:07  brouard
                    566:   (Module): varevsij Comments added explaining the second
                    567:   table of variances if popbased=1 .
                    568:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    569:   (Module): Function pstamp added
                    570:   (Module): Version 0.98d
                    571: 
                    572:   Revision 1.117  2006/03/14 17:16:22  brouard
                    573:   (Module): varevsij Comments added explaining the second
                    574:   table of variances if popbased=1 .
                    575:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    576:   (Module): Function pstamp added
                    577:   (Module): Version 0.98d
                    578: 
                    579:   Revision 1.116  2006/03/06 10:29:27  brouard
                    580:   (Module): Variance-covariance wrong links and
                    581:   varian-covariance of ej. is needed (Saito).
                    582: 
                    583:   Revision 1.115  2006/02/27 12:17:45  brouard
                    584:   (Module): One freematrix added in mlikeli! 0.98c
                    585: 
                    586:   Revision 1.114  2006/02/26 12:57:58  brouard
                    587:   (Module): Some improvements in processing parameter
                    588:   filename with strsep.
                    589: 
                    590:   Revision 1.113  2006/02/24 14:20:24  brouard
                    591:   (Module): Memory leaks checks with valgrind and:
                    592:   datafile was not closed, some imatrix were not freed and on matrix
                    593:   allocation too.
                    594: 
                    595:   Revision 1.112  2006/01/30 09:55:26  brouard
                    596:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    597: 
                    598:   Revision 1.111  2006/01/25 20:38:18  brouard
                    599:   (Module): Lots of cleaning and bugs added (Gompertz)
                    600:   (Module): Comments can be added in data file. Missing date values
                    601:   can be a simple dot '.'.
                    602: 
                    603:   Revision 1.110  2006/01/25 00:51:50  brouard
                    604:   (Module): Lots of cleaning and bugs added (Gompertz)
                    605: 
                    606:   Revision 1.109  2006/01/24 19:37:15  brouard
                    607:   (Module): Comments (lines starting with a #) are allowed in data.
                    608: 
                    609:   Revision 1.108  2006/01/19 18:05:42  lievre
                    610:   Gnuplot problem appeared...
                    611:   To be fixed
                    612: 
                    613:   Revision 1.107  2006/01/19 16:20:37  brouard
                    614:   Test existence of gnuplot in imach path
                    615: 
                    616:   Revision 1.106  2006/01/19 13:24:36  brouard
                    617:   Some cleaning and links added in html output
                    618: 
                    619:   Revision 1.105  2006/01/05 20:23:19  lievre
                    620:   *** empty log message ***
                    621: 
                    622:   Revision 1.104  2005/09/30 16:11:43  lievre
                    623:   (Module): sump fixed, loop imx fixed, and simplifications.
                    624:   (Module): If the status is missing at the last wave but we know
                    625:   that the person is alive, then we can code his/her status as -2
                    626:   (instead of missing=-1 in earlier versions) and his/her
                    627:   contributions to the likelihood is 1 - Prob of dying from last
                    628:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    629:   the healthy state at last known wave). Version is 0.98
                    630: 
                    631:   Revision 1.103  2005/09/30 15:54:49  lievre
                    632:   (Module): sump fixed, loop imx fixed, and simplifications.
                    633: 
                    634:   Revision 1.102  2004/09/15 17:31:30  brouard
                    635:   Add the possibility to read data file including tab characters.
                    636: 
                    637:   Revision 1.101  2004/09/15 10:38:38  brouard
                    638:   Fix on curr_time
                    639: 
                    640:   Revision 1.100  2004/07/12 18:29:06  brouard
                    641:   Add version for Mac OS X. Just define UNIX in Makefile
                    642: 
                    643:   Revision 1.99  2004/06/05 08:57:40  brouard
                    644:   *** empty log message ***
                    645: 
                    646:   Revision 1.98  2004/05/16 15:05:56  brouard
                    647:   New version 0.97 . First attempt to estimate force of mortality
                    648:   directly from the data i.e. without the need of knowing the health
                    649:   state at each age, but using a Gompertz model: log u =a + b*age .
                    650:   This is the basic analysis of mortality and should be done before any
                    651:   other analysis, in order to test if the mortality estimated from the
                    652:   cross-longitudinal survey is different from the mortality estimated
                    653:   from other sources like vital statistic data.
                    654: 
                    655:   The same imach parameter file can be used but the option for mle should be -3.
                    656: 
1.133     brouard   657:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   658:   former routines in order to include the new code within the former code.
                    659: 
                    660:   The output is very simple: only an estimate of the intercept and of
                    661:   the slope with 95% confident intervals.
                    662: 
                    663:   Current limitations:
                    664:   A) Even if you enter covariates, i.e. with the
                    665:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    666:   B) There is no computation of Life Expectancy nor Life Table.
                    667: 
                    668:   Revision 1.97  2004/02/20 13:25:42  lievre
                    669:   Version 0.96d. Population forecasting command line is (temporarily)
                    670:   suppressed.
                    671: 
                    672:   Revision 1.96  2003/07/15 15:38:55  brouard
                    673:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    674:   rewritten within the same printf. Workaround: many printfs.
                    675: 
                    676:   Revision 1.95  2003/07/08 07:54:34  brouard
                    677:   * imach.c (Repository):
                    678:   (Repository): Using imachwizard code to output a more meaningful covariance
                    679:   matrix (cov(a12,c31) instead of numbers.
                    680: 
                    681:   Revision 1.94  2003/06/27 13:00:02  brouard
                    682:   Just cleaning
                    683: 
                    684:   Revision 1.93  2003/06/25 16:33:55  brouard
                    685:   (Module): On windows (cygwin) function asctime_r doesn't
                    686:   exist so I changed back to asctime which exists.
                    687:   (Module): Version 0.96b
                    688: 
                    689:   Revision 1.92  2003/06/25 16:30:45  brouard
                    690:   (Module): On windows (cygwin) function asctime_r doesn't
                    691:   exist so I changed back to asctime which exists.
                    692: 
                    693:   Revision 1.91  2003/06/25 15:30:29  brouard
                    694:   * imach.c (Repository): Duplicated warning errors corrected.
                    695:   (Repository): Elapsed time after each iteration is now output. It
                    696:   helps to forecast when convergence will be reached. Elapsed time
                    697:   is stamped in powell.  We created a new html file for the graphs
                    698:   concerning matrix of covariance. It has extension -cov.htm.
                    699: 
                    700:   Revision 1.90  2003/06/24 12:34:15  brouard
                    701:   (Module): Some bugs corrected for windows. Also, when
                    702:   mle=-1 a template is output in file "or"mypar.txt with the design
                    703:   of the covariance matrix to be input.
                    704: 
                    705:   Revision 1.89  2003/06/24 12:30:52  brouard
                    706:   (Module): Some bugs corrected for windows. Also, when
                    707:   mle=-1 a template is output in file "or"mypar.txt with the design
                    708:   of the covariance matrix to be input.
                    709: 
                    710:   Revision 1.88  2003/06/23 17:54:56  brouard
                    711:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    712: 
                    713:   Revision 1.87  2003/06/18 12:26:01  brouard
                    714:   Version 0.96
                    715: 
                    716:   Revision 1.86  2003/06/17 20:04:08  brouard
                    717:   (Module): Change position of html and gnuplot routines and added
                    718:   routine fileappend.
                    719: 
                    720:   Revision 1.85  2003/06/17 13:12:43  brouard
                    721:   * imach.c (Repository): Check when date of death was earlier that
                    722:   current date of interview. It may happen when the death was just
                    723:   prior to the death. In this case, dh was negative and likelihood
                    724:   was wrong (infinity). We still send an "Error" but patch by
                    725:   assuming that the date of death was just one stepm after the
                    726:   interview.
                    727:   (Repository): Because some people have very long ID (first column)
                    728:   we changed int to long in num[] and we added a new lvector for
                    729:   memory allocation. But we also truncated to 8 characters (left
                    730:   truncation)
                    731:   (Repository): No more line truncation errors.
                    732: 
                    733:   Revision 1.84  2003/06/13 21:44:43  brouard
                    734:   * imach.c (Repository): Replace "freqsummary" at a correct
                    735:   place. It differs from routine "prevalence" which may be called
                    736:   many times. Probs is memory consuming and must be used with
                    737:   parcimony.
                    738:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    739: 
                    740:   Revision 1.83  2003/06/10 13:39:11  lievre
                    741:   *** empty log message ***
                    742: 
                    743:   Revision 1.82  2003/06/05 15:57:20  brouard
                    744:   Add log in  imach.c and  fullversion number is now printed.
                    745: 
                    746: */
                    747: /*
                    748:    Interpolated Markov Chain
                    749: 
                    750:   Short summary of the programme:
                    751:   
1.227     brouard   752:   This program computes Healthy Life Expectancies or State-specific
                    753:   (if states aren't health statuses) Expectancies from
                    754:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    755: 
                    756:   -1- a first survey ("cross") where individuals from different ages
                    757:   are interviewed on their health status or degree of disability (in
                    758:   the case of a health survey which is our main interest)
                    759: 
                    760:   -2- at least a second wave of interviews ("longitudinal") which
                    761:   measure each change (if any) in individual health status.  Health
                    762:   expectancies are computed from the time spent in each health state
                    763:   according to a model. More health states you consider, more time is
                    764:   necessary to reach the Maximum Likelihood of the parameters involved
                    765:   in the model.  The simplest model is the multinomial logistic model
                    766:   where pij is the probability to be observed in state j at the second
                    767:   wave conditional to be observed in state i at the first
                    768:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    769:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    770:   have a more complex model than "constant and age", you should modify
                    771:   the program where the markup *Covariates have to be included here
                    772:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   773:   convergence.
                    774: 
                    775:   The advantage of this computer programme, compared to a simple
                    776:   multinomial logistic model, is clear when the delay between waves is not
                    777:   identical for each individual. Also, if a individual missed an
                    778:   intermediate interview, the information is lost, but taken into
                    779:   account using an interpolation or extrapolation.  
                    780: 
                    781:   hPijx is the probability to be observed in state i at age x+h
                    782:   conditional to the observed state i at age x. The delay 'h' can be
                    783:   split into an exact number (nh*stepm) of unobserved intermediate
                    784:   states. This elementary transition (by month, quarter,
                    785:   semester or year) is modelled as a multinomial logistic.  The hPx
                    786:   matrix is simply the matrix product of nh*stepm elementary matrices
                    787:   and the contribution of each individual to the likelihood is simply
                    788:   hPijx.
                    789: 
                    790:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   791:   of the life expectancies. It also computes the period (stable) prevalence.
                    792: 
                    793: Back prevalence and projections:
1.227     brouard   794: 
                    795:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    796:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    797:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    798:    mobilavproj)
                    799: 
                    800:     Computes the back prevalence limit for any combination of
                    801:     covariate values k at any age between ageminpar and agemaxpar and
                    802:     returns it in **bprlim. In the loops,
                    803: 
                    804:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    805:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    806: 
                    807:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   808:    Computes for any combination of covariates k and any age between bage and fage 
                    809:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    810:                        oldm=oldms;savm=savms;
1.227     brouard   811: 
                    812:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   813:      Computes the transition matrix starting at age 'age' over
                    814:      'nhstepm*hstepm*stepm' months (i.e. until
                    815:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   816:      nhstepm*hstepm matrices. 
                    817: 
                    818:      Returns p3mat[i][j][h] after calling
                    819:      p3mat[i][j][h]=matprod2(newm,
                    820:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    821:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    822:      oldm);
1.226     brouard   823: 
                    824: Important routines
                    825: 
                    826: - func (or funcone), computes logit (pij) distinguishing
                    827:   o fixed variables (single or product dummies or quantitative);
                    828:   o varying variables by:
                    829:    (1) wave (single, product dummies, quantitative), 
                    830:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    831:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    832:        % varying dummy (not done) or quantitative (not done);
                    833: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    834:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    835: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    836:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    837:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   838: 
1.226     brouard   839: 
                    840:   
1.133     brouard   841:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    842:            Institut national d'études démographiques, Paris.
1.126     brouard   843:   This software have been partly granted by Euro-REVES, a concerted action
                    844:   from the European Union.
                    845:   It is copyrighted identically to a GNU software product, ie programme and
                    846:   software can be distributed freely for non commercial use. Latest version
                    847:   can be accessed at http://euroreves.ined.fr/imach .
                    848: 
                    849:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    850:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    851:   
                    852:   **********************************************************************/
                    853: /*
                    854:   main
                    855:   read parameterfile
                    856:   read datafile
                    857:   concatwav
                    858:   freqsummary
                    859:   if (mle >= 1)
                    860:     mlikeli
                    861:   print results files
                    862:   if mle==1 
                    863:      computes hessian
                    864:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    865:       begin-prev-date,...
                    866:   open gnuplot file
                    867:   open html file
1.145     brouard   868:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    869:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    870:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    871:     freexexit2 possible for memory heap.
                    872: 
                    873:   h Pij x                         | pij_nom  ficrestpij
                    874:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    875:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    876:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    877: 
                    878:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    879:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    880:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    881:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    882:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    883: 
1.126     brouard   884:   forecasting if prevfcast==1 prevforecast call prevalence()
                    885:   health expectancies
                    886:   Variance-covariance of DFLE
                    887:   prevalence()
                    888:    movingaverage()
                    889:   varevsij() 
                    890:   if popbased==1 varevsij(,popbased)
                    891:   total life expectancies
                    892:   Variance of period (stable) prevalence
                    893:  end
                    894: */
                    895: 
1.187     brouard   896: /* #define DEBUG */
                    897: /* #define DEBUGBRENT */
1.203     brouard   898: /* #define DEBUGLINMIN */
                    899: /* #define DEBUGHESS */
                    900: #define DEBUGHESSIJ
1.224     brouard   901: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   902: #define POWELL /* Instead of NLOPT */
1.224     brouard   903: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   904: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    905: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   906: 
                    907: #include <math.h>
                    908: #include <stdio.h>
                    909: #include <stdlib.h>
                    910: #include <string.h>
1.226     brouard   911: #include <ctype.h>
1.159     brouard   912: 
                    913: #ifdef _WIN32
                    914: #include <io.h>
1.172     brouard   915: #include <windows.h>
                    916: #include <tchar.h>
1.159     brouard   917: #else
1.126     brouard   918: #include <unistd.h>
1.159     brouard   919: #endif
1.126     brouard   920: 
                    921: #include <limits.h>
                    922: #include <sys/types.h>
1.171     brouard   923: 
                    924: #if defined(__GNUC__)
                    925: #include <sys/utsname.h> /* Doesn't work on Windows */
                    926: #endif
                    927: 
1.126     brouard   928: #include <sys/stat.h>
                    929: #include <errno.h>
1.159     brouard   930: /* extern int errno; */
1.126     brouard   931: 
1.157     brouard   932: /* #ifdef LINUX */
                    933: /* #include <time.h> */
                    934: /* #include "timeval.h" */
                    935: /* #else */
                    936: /* #include <sys/time.h> */
                    937: /* #endif */
                    938: 
1.126     brouard   939: #include <time.h>
                    940: 
1.136     brouard   941: #ifdef GSL
                    942: #include <gsl/gsl_errno.h>
                    943: #include <gsl/gsl_multimin.h>
                    944: #endif
                    945: 
1.167     brouard   946: 
1.162     brouard   947: #ifdef NLOPT
                    948: #include <nlopt.h>
                    949: typedef struct {
                    950:   double (* function)(double [] );
                    951: } myfunc_data ;
                    952: #endif
                    953: 
1.126     brouard   954: /* #include <libintl.h> */
                    955: /* #define _(String) gettext (String) */
                    956: 
1.251     brouard   957: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   958: 
                    959: #define GNUPLOTPROGRAM "gnuplot"
                    960: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    961: #define FILENAMELENGTH 132
                    962: 
                    963: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    964: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    965: 
1.144     brouard   966: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    967: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   968: 
                    969: #define NINTERVMAX 8
1.144     brouard   970: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    971: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    972: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   973: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   974: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    975: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   976: #define MAXN 20000
1.144     brouard   977: #define YEARM 12. /**< Number of months per year */
1.218     brouard   978: /* #define AGESUP 130 */
                    979: #define AGESUP 150
                    980: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   981: #define AGEBASE 40
1.194     brouard   982: #define AGEOVERFLOW 1.e20
1.164     brouard   983: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   984: #ifdef _WIN32
                    985: #define DIRSEPARATOR '\\'
                    986: #define CHARSEPARATOR "\\"
                    987: #define ODIRSEPARATOR '/'
                    988: #else
1.126     brouard   989: #define DIRSEPARATOR '/'
                    990: #define CHARSEPARATOR "/"
                    991: #define ODIRSEPARATOR '\\'
                    992: #endif
                    993: 
1.264   ! brouard   994: /* $Id: imach.c,v 1.263 2017/04/24 15:23:15 brouard Exp $ */
1.126     brouard   995: /* $State: Exp $ */
1.196     brouard   996: #include "version.h"
                    997: char version[]=__IMACH_VERSION__;
1.224     brouard   998: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.264   ! brouard   999: char fullversion[]="$Revision: 1.263 $ $Date: 2017/04/24 15:23:15 $"; 
1.126     brouard  1000: char strstart[80];
                   1001: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1002: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1003: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1004: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1005: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1006: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1007: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1008: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1009: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1010: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1011: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1012: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1013: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1014: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1015: int nsd=0; /**< Total number of single dummy variables (output) */
                   1016: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1017: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1018: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1019: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1020: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1021: int cptcov=0; /* Working variable */
1.218     brouard  1022: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1023: int npar=NPARMAX;
                   1024: int nlstate=2; /* Number of live states */
                   1025: int ndeath=1; /* Number of dead states */
1.130     brouard  1026: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1027: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1028: int popbased=0;
                   1029: 
                   1030: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1031: int maxwav=0; /* Maxim number of waves */
                   1032: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1033: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1034: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1035:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1036: int mle=1, weightopt=0;
1.126     brouard  1037: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1038: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1039: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1040:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1041: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1042: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1043: 
1.130     brouard  1044: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1045: double **matprod2(); /* test */
1.126     brouard  1046: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1047: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1048: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1049: 
1.136     brouard  1050: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1051: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1052: FILE *ficlog, *ficrespow;
1.130     brouard  1053: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1054: double fretone; /* Only one call to likelihood */
1.130     brouard  1055: long ipmx=0; /* Number of contributions */
1.126     brouard  1056: double sw; /* Sum of weights */
                   1057: char filerespow[FILENAMELENGTH];
                   1058: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1059: FILE *ficresilk;
                   1060: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1061: FILE *ficresprobmorprev;
                   1062: FILE *fichtm, *fichtmcov; /* Html File */
                   1063: FILE *ficreseij;
                   1064: char filerese[FILENAMELENGTH];
                   1065: FILE *ficresstdeij;
                   1066: char fileresstde[FILENAMELENGTH];
                   1067: FILE *ficrescveij;
                   1068: char filerescve[FILENAMELENGTH];
                   1069: FILE  *ficresvij;
                   1070: char fileresv[FILENAMELENGTH];
                   1071: FILE  *ficresvpl;
                   1072: char fileresvpl[FILENAMELENGTH];
                   1073: char title[MAXLINE];
1.234     brouard  1074: char model[MAXLINE]; /**< The model line */
1.217     brouard  1075: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1076: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1077: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1078: char command[FILENAMELENGTH];
                   1079: int  outcmd=0;
                   1080: 
1.217     brouard  1081: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1082: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1083: char filelog[FILENAMELENGTH]; /* Log file */
                   1084: char filerest[FILENAMELENGTH];
                   1085: char fileregp[FILENAMELENGTH];
                   1086: char popfile[FILENAMELENGTH];
                   1087: 
                   1088: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1089: 
1.157     brouard  1090: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1091: /* struct timezone tzp; */
                   1092: /* extern int gettimeofday(); */
                   1093: struct tm tml, *gmtime(), *localtime();
                   1094: 
                   1095: extern time_t time();
                   1096: 
                   1097: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1098: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1099: struct tm tm;
                   1100: 
1.126     brouard  1101: char strcurr[80], strfor[80];
                   1102: 
                   1103: char *endptr;
                   1104: long lval;
                   1105: double dval;
                   1106: 
                   1107: #define NR_END 1
                   1108: #define FREE_ARG char*
                   1109: #define FTOL 1.0e-10
                   1110: 
                   1111: #define NRANSI 
1.240     brouard  1112: #define ITMAX 200
                   1113: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1114: 
                   1115: #define TOL 2.0e-4 
                   1116: 
                   1117: #define CGOLD 0.3819660 
                   1118: #define ZEPS 1.0e-10 
                   1119: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1120: 
                   1121: #define GOLD 1.618034 
                   1122: #define GLIMIT 100.0 
                   1123: #define TINY 1.0e-20 
                   1124: 
                   1125: static double maxarg1,maxarg2;
                   1126: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1127: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1128:   
                   1129: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1130: #define rint(a) floor(a+0.5)
1.166     brouard  1131: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1132: #define mytinydouble 1.0e-16
1.166     brouard  1133: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1134: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1135: /* static double dsqrarg; */
                   1136: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1137: static double sqrarg;
                   1138: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1139: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1140: int agegomp= AGEGOMP;
                   1141: 
                   1142: int imx; 
                   1143: int stepm=1;
                   1144: /* Stepm, step in month: minimum step interpolation*/
                   1145: 
                   1146: int estepm;
                   1147: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1148: 
                   1149: int m,nb;
                   1150: long *num;
1.197     brouard  1151: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1152: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1153:                   covariate for which somebody answered excluding 
                   1154:                   undefined. Usually 2: 0 and 1. */
                   1155: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1156:                             covariate for which somebody answered including 
                   1157:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1158: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1159: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1160: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1161: double *ageexmed,*agecens;
                   1162: double dateintmean=0;
                   1163: 
                   1164: double *weight;
                   1165: int **s; /* Status */
1.141     brouard  1166: double *agedc;
1.145     brouard  1167: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1168:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1169:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1170: double **coqvar; /* Fixed quantitative covariate iqv */
                   1171: double ***cotvar; /* Time varying covariate itv */
                   1172: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1173: double  idx; 
                   1174: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1175: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1176: /*k          1  2   3   4     5    6    7     8    9 */
                   1177: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1178: /* Tndvar[k]    1   2   3               4          5 */
                   1179: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1180: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1181: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1182: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1183: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1184: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1185: /* Tprod[i]=k           4               7            */
                   1186: /* Tage[i]=k                  5               8      */
                   1187: /* */
                   1188: /* Type                    */
                   1189: /* V         1  2  3  4  5 */
                   1190: /*           F  F  V  V  V */
                   1191: /*           D  Q  D  D  Q */
                   1192: /*                         */
                   1193: int *TvarsD;
                   1194: int *TvarsDind;
                   1195: int *TvarsQ;
                   1196: int *TvarsQind;
                   1197: 
1.235     brouard  1198: #define MAXRESULTLINES 10
                   1199: int nresult=0;
1.258     brouard  1200: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1201: int TKresult[MAXRESULTLINES];
1.237     brouard  1202: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1203: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1204: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1205: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1206: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1207: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1208: 
1.234     brouard  1209: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1210: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1211: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1212: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1213: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1214: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1215: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1216: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1217: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1218: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1219: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1220: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1221: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1222: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1223: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1224: 
1.230     brouard  1225: int *Tvarsel; /**< Selected covariates for output */
                   1226: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1227: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1228: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1229: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1230: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1231: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1232: int *Tage;
1.227     brouard  1233: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1234: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1235: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1236: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1237: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1238: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1239: int **Tvard;
                   1240: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1241: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1242: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1243:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1244:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1245: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1246: double *lsurv, *lpop, *tpop;
                   1247: 
1.231     brouard  1248: #define FD 1; /* Fixed dummy covariate */
                   1249: #define FQ 2; /* Fixed quantitative covariate */
                   1250: #define FP 3; /* Fixed product covariate */
                   1251: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1252: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1253: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1254: #define VD 10; /* Varying dummy covariate */
                   1255: #define VQ 11; /* Varying quantitative covariate */
                   1256: #define VP 12; /* Varying product covariate */
                   1257: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1258: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1259: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1260: #define APFD 16; /* Age product * fixed dummy covariate */
                   1261: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1262: #define APVD 18; /* Age product * varying dummy covariate */
                   1263: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1264: 
                   1265: #define FTYPE 1; /* Fixed covariate */
                   1266: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1267: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1268: 
                   1269: struct kmodel{
                   1270:        int maintype; /* main type */
                   1271:        int subtype; /* subtype */
                   1272: };
                   1273: struct kmodel modell[NCOVMAX];
                   1274: 
1.143     brouard  1275: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1276: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1277: 
                   1278: /**************** split *************************/
                   1279: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1280: {
                   1281:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1282:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1283:   */ 
                   1284:   char *ss;                            /* pointer */
1.186     brouard  1285:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1286: 
                   1287:   l1 = strlen(path );                  /* length of path */
                   1288:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1289:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1290:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1291:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1292:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1293:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1294:     /* get current working directory */
                   1295:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1296: #ifdef WIN32
                   1297:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1298: #else
                   1299:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1300: #endif
1.126     brouard  1301:       return( GLOCK_ERROR_GETCWD );
                   1302:     }
                   1303:     /* got dirc from getcwd*/
                   1304:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1305:   } else {                             /* strip directory from path */
1.126     brouard  1306:     ss++;                              /* after this, the filename */
                   1307:     l2 = strlen( ss );                 /* length of filename */
                   1308:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1309:     strcpy( name, ss );                /* save file name */
                   1310:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1311:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1312:     printf(" DIRC2 = %s \n",dirc);
                   1313:   }
                   1314:   /* We add a separator at the end of dirc if not exists */
                   1315:   l1 = strlen( dirc );                 /* length of directory */
                   1316:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1317:     dirc[l1] =  DIRSEPARATOR;
                   1318:     dirc[l1+1] = 0; 
                   1319:     printf(" DIRC3 = %s \n",dirc);
                   1320:   }
                   1321:   ss = strrchr( name, '.' );           /* find last / */
                   1322:   if (ss >0){
                   1323:     ss++;
                   1324:     strcpy(ext,ss);                    /* save extension */
                   1325:     l1= strlen( name);
                   1326:     l2= strlen(ss)+1;
                   1327:     strncpy( finame, name, l1-l2);
                   1328:     finame[l1-l2]= 0;
                   1329:   }
                   1330: 
                   1331:   return( 0 );                         /* we're done */
                   1332: }
                   1333: 
                   1334: 
                   1335: /******************************************/
                   1336: 
                   1337: void replace_back_to_slash(char *s, char*t)
                   1338: {
                   1339:   int i;
                   1340:   int lg=0;
                   1341:   i=0;
                   1342:   lg=strlen(t);
                   1343:   for(i=0; i<= lg; i++) {
                   1344:     (s[i] = t[i]);
                   1345:     if (t[i]== '\\') s[i]='/';
                   1346:   }
                   1347: }
                   1348: 
1.132     brouard  1349: char *trimbb(char *out, char *in)
1.137     brouard  1350: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1351:   char *s;
                   1352:   s=out;
                   1353:   while (*in != '\0'){
1.137     brouard  1354:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1355:       in++;
                   1356:     }
                   1357:     *out++ = *in++;
                   1358:   }
                   1359:   *out='\0';
                   1360:   return s;
                   1361: }
                   1362: 
1.187     brouard  1363: /* char *substrchaine(char *out, char *in, char *chain) */
                   1364: /* { */
                   1365: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1366: /*   char *s, *t; */
                   1367: /*   t=in;s=out; */
                   1368: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1369: /*     *out++ = *in++; */
                   1370: /*   } */
                   1371: 
                   1372: /*   /\* *in matches *chain *\/ */
                   1373: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1374: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1375: /*   } */
                   1376: /*   in--; chain--; */
                   1377: /*   while ( (*in != '\0')){ */
                   1378: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1379: /*     *out++ = *in++; */
                   1380: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1381: /*   } */
                   1382: /*   *out='\0'; */
                   1383: /*   out=s; */
                   1384: /*   return out; */
                   1385: /* } */
                   1386: char *substrchaine(char *out, char *in, char *chain)
                   1387: {
                   1388:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1389:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1390: 
                   1391:   char *strloc;
                   1392: 
                   1393:   strcpy (out, in); 
                   1394:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1395:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1396:   if(strloc != NULL){ 
                   1397:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1398:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1399:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1400:   }
                   1401:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1402:   return out;
                   1403: }
                   1404: 
                   1405: 
1.145     brouard  1406: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1407: {
1.187     brouard  1408:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1409:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1410:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1411:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1412:   */
1.160     brouard  1413:   char *s, *t;
1.145     brouard  1414:   t=in;s=in;
                   1415:   while ((*in != occ) && (*in != '\0')){
                   1416:     *alocc++ = *in++;
                   1417:   }
                   1418:   if( *in == occ){
                   1419:     *(alocc)='\0';
                   1420:     s=++in;
                   1421:   }
                   1422:  
                   1423:   if (s == t) {/* occ not found */
                   1424:     *(alocc-(in-s))='\0';
                   1425:     in=s;
                   1426:   }
                   1427:   while ( *in != '\0'){
                   1428:     *blocc++ = *in++;
                   1429:   }
                   1430: 
                   1431:   *blocc='\0';
                   1432:   return t;
                   1433: }
1.137     brouard  1434: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1435: {
1.187     brouard  1436:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1437:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1438:      gives blocc="abcdef2ghi" and alocc="j".
                   1439:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1440:   */
                   1441:   char *s, *t;
                   1442:   t=in;s=in;
                   1443:   while (*in != '\0'){
                   1444:     while( *in == occ){
                   1445:       *blocc++ = *in++;
                   1446:       s=in;
                   1447:     }
                   1448:     *blocc++ = *in++;
                   1449:   }
                   1450:   if (s == t) /* occ not found */
                   1451:     *(blocc-(in-s))='\0';
                   1452:   else
                   1453:     *(blocc-(in-s)-1)='\0';
                   1454:   in=s;
                   1455:   while ( *in != '\0'){
                   1456:     *alocc++ = *in++;
                   1457:   }
                   1458: 
                   1459:   *alocc='\0';
                   1460:   return s;
                   1461: }
                   1462: 
1.126     brouard  1463: int nbocc(char *s, char occ)
                   1464: {
                   1465:   int i,j=0;
                   1466:   int lg=20;
                   1467:   i=0;
                   1468:   lg=strlen(s);
                   1469:   for(i=0; i<= lg; i++) {
1.234     brouard  1470:     if  (s[i] == occ ) j++;
1.126     brouard  1471:   }
                   1472:   return j;
                   1473: }
                   1474: 
1.137     brouard  1475: /* void cutv(char *u,char *v, char*t, char occ) */
                   1476: /* { */
                   1477: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1478: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1479: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1480: /*   int i,lg,j,p=0; */
                   1481: /*   i=0; */
                   1482: /*   lg=strlen(t); */
                   1483: /*   for(j=0; j<=lg-1; j++) { */
                   1484: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1485: /*   } */
1.126     brouard  1486: 
1.137     brouard  1487: /*   for(j=0; j<p; j++) { */
                   1488: /*     (u[j] = t[j]); */
                   1489: /*   } */
                   1490: /*      u[p]='\0'; */
1.126     brouard  1491: 
1.137     brouard  1492: /*    for(j=0; j<= lg; j++) { */
                   1493: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1494: /*   } */
                   1495: /* } */
1.126     brouard  1496: 
1.160     brouard  1497: #ifdef _WIN32
                   1498: char * strsep(char **pp, const char *delim)
                   1499: {
                   1500:   char *p, *q;
                   1501:          
                   1502:   if ((p = *pp) == NULL)
                   1503:     return 0;
                   1504:   if ((q = strpbrk (p, delim)) != NULL)
                   1505:   {
                   1506:     *pp = q + 1;
                   1507:     *q = '\0';
                   1508:   }
                   1509:   else
                   1510:     *pp = 0;
                   1511:   return p;
                   1512: }
                   1513: #endif
                   1514: 
1.126     brouard  1515: /********************** nrerror ********************/
                   1516: 
                   1517: void nrerror(char error_text[])
                   1518: {
                   1519:   fprintf(stderr,"ERREUR ...\n");
                   1520:   fprintf(stderr,"%s\n",error_text);
                   1521:   exit(EXIT_FAILURE);
                   1522: }
                   1523: /*********************** vector *******************/
                   1524: double *vector(int nl, int nh)
                   1525: {
                   1526:   double *v;
                   1527:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1528:   if (!v) nrerror("allocation failure in vector");
                   1529:   return v-nl+NR_END;
                   1530: }
                   1531: 
                   1532: /************************ free vector ******************/
                   1533: void free_vector(double*v, int nl, int nh)
                   1534: {
                   1535:   free((FREE_ARG)(v+nl-NR_END));
                   1536: }
                   1537: 
                   1538: /************************ivector *******************************/
                   1539: int *ivector(long nl,long nh)
                   1540: {
                   1541:   int *v;
                   1542:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1543:   if (!v) nrerror("allocation failure in ivector");
                   1544:   return v-nl+NR_END;
                   1545: }
                   1546: 
                   1547: /******************free ivector **************************/
                   1548: void free_ivector(int *v, long nl, long nh)
                   1549: {
                   1550:   free((FREE_ARG)(v+nl-NR_END));
                   1551: }
                   1552: 
                   1553: /************************lvector *******************************/
                   1554: long *lvector(long nl,long nh)
                   1555: {
                   1556:   long *v;
                   1557:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1558:   if (!v) nrerror("allocation failure in ivector");
                   1559:   return v-nl+NR_END;
                   1560: }
                   1561: 
                   1562: /******************free lvector **************************/
                   1563: void free_lvector(long *v, long nl, long nh)
                   1564: {
                   1565:   free((FREE_ARG)(v+nl-NR_END));
                   1566: }
                   1567: 
                   1568: /******************* imatrix *******************************/
                   1569: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1570:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1571: { 
                   1572:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1573:   int **m; 
                   1574:   
                   1575:   /* allocate pointers to rows */ 
                   1576:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1577:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1578:   m += NR_END; 
                   1579:   m -= nrl; 
                   1580:   
                   1581:   
                   1582:   /* allocate rows and set pointers to them */ 
                   1583:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1584:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1585:   m[nrl] += NR_END; 
                   1586:   m[nrl] -= ncl; 
                   1587:   
                   1588:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1589:   
                   1590:   /* return pointer to array of pointers to rows */ 
                   1591:   return m; 
                   1592: } 
                   1593: 
                   1594: /****************** free_imatrix *************************/
                   1595: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1596:       int **m;
                   1597:       long nch,ncl,nrh,nrl; 
                   1598:      /* free an int matrix allocated by imatrix() */ 
                   1599: { 
                   1600:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1601:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1602: } 
                   1603: 
                   1604: /******************* matrix *******************************/
                   1605: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1606: {
                   1607:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1608:   double **m;
                   1609: 
                   1610:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1611:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1612:   m += NR_END;
                   1613:   m -= nrl;
                   1614: 
                   1615:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1616:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1617:   m[nrl] += NR_END;
                   1618:   m[nrl] -= ncl;
                   1619: 
                   1620:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1621:   return m;
1.145     brouard  1622:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1623: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1624: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1625:    */
                   1626: }
                   1627: 
                   1628: /*************************free matrix ************************/
                   1629: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1630: {
                   1631:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1632:   free((FREE_ARG)(m+nrl-NR_END));
                   1633: }
                   1634: 
                   1635: /******************* ma3x *******************************/
                   1636: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1637: {
                   1638:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1639:   double ***m;
                   1640: 
                   1641:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1642:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1643:   m += NR_END;
                   1644:   m -= nrl;
                   1645: 
                   1646:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1647:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1648:   m[nrl] += NR_END;
                   1649:   m[nrl] -= ncl;
                   1650: 
                   1651:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1652: 
                   1653:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1654:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1655:   m[nrl][ncl] += NR_END;
                   1656:   m[nrl][ncl] -= nll;
                   1657:   for (j=ncl+1; j<=nch; j++) 
                   1658:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1659:   
                   1660:   for (i=nrl+1; i<=nrh; i++) {
                   1661:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1662:     for (j=ncl+1; j<=nch; j++) 
                   1663:       m[i][j]=m[i][j-1]+nlay;
                   1664:   }
                   1665:   return m; 
                   1666:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1667:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1668:   */
                   1669: }
                   1670: 
                   1671: /*************************free ma3x ************************/
                   1672: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1673: {
                   1674:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1675:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1676:   free((FREE_ARG)(m+nrl-NR_END));
                   1677: }
                   1678: 
                   1679: /*************** function subdirf ***********/
                   1680: char *subdirf(char fileres[])
                   1681: {
                   1682:   /* Caution optionfilefiname is hidden */
                   1683:   strcpy(tmpout,optionfilefiname);
                   1684:   strcat(tmpout,"/"); /* Add to the right */
                   1685:   strcat(tmpout,fileres);
                   1686:   return tmpout;
                   1687: }
                   1688: 
                   1689: /*************** function subdirf2 ***********/
                   1690: char *subdirf2(char fileres[], char *preop)
                   1691: {
                   1692:   
                   1693:   /* Caution optionfilefiname is hidden */
                   1694:   strcpy(tmpout,optionfilefiname);
                   1695:   strcat(tmpout,"/");
                   1696:   strcat(tmpout,preop);
                   1697:   strcat(tmpout,fileres);
                   1698:   return tmpout;
                   1699: }
                   1700: 
                   1701: /*************** function subdirf3 ***********/
                   1702: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1703: {
                   1704:   
                   1705:   /* Caution optionfilefiname is hidden */
                   1706:   strcpy(tmpout,optionfilefiname);
                   1707:   strcat(tmpout,"/");
                   1708:   strcat(tmpout,preop);
                   1709:   strcat(tmpout,preop2);
                   1710:   strcat(tmpout,fileres);
                   1711:   return tmpout;
                   1712: }
1.213     brouard  1713:  
                   1714: /*************** function subdirfext ***********/
                   1715: char *subdirfext(char fileres[], char *preop, char *postop)
                   1716: {
                   1717:   
                   1718:   strcpy(tmpout,preop);
                   1719:   strcat(tmpout,fileres);
                   1720:   strcat(tmpout,postop);
                   1721:   return tmpout;
                   1722: }
1.126     brouard  1723: 
1.213     brouard  1724: /*************** function subdirfext3 ***********/
                   1725: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1726: {
                   1727:   
                   1728:   /* Caution optionfilefiname is hidden */
                   1729:   strcpy(tmpout,optionfilefiname);
                   1730:   strcat(tmpout,"/");
                   1731:   strcat(tmpout,preop);
                   1732:   strcat(tmpout,fileres);
                   1733:   strcat(tmpout,postop);
                   1734:   return tmpout;
                   1735: }
                   1736:  
1.162     brouard  1737: char *asc_diff_time(long time_sec, char ascdiff[])
                   1738: {
                   1739:   long sec_left, days, hours, minutes;
                   1740:   days = (time_sec) / (60*60*24);
                   1741:   sec_left = (time_sec) % (60*60*24);
                   1742:   hours = (sec_left) / (60*60) ;
                   1743:   sec_left = (sec_left) %(60*60);
                   1744:   minutes = (sec_left) /60;
                   1745:   sec_left = (sec_left) % (60);
                   1746:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1747:   return ascdiff;
                   1748: }
                   1749: 
1.126     brouard  1750: /***************** f1dim *************************/
                   1751: extern int ncom; 
                   1752: extern double *pcom,*xicom;
                   1753: extern double (*nrfunc)(double []); 
                   1754:  
                   1755: double f1dim(double x) 
                   1756: { 
                   1757:   int j; 
                   1758:   double f;
                   1759:   double *xt; 
                   1760:  
                   1761:   xt=vector(1,ncom); 
                   1762:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1763:   f=(*nrfunc)(xt); 
                   1764:   free_vector(xt,1,ncom); 
                   1765:   return f; 
                   1766: } 
                   1767: 
                   1768: /*****************brent *************************/
                   1769: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1770: {
                   1771:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1772:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1773:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1774:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1775:    * returned function value. 
                   1776:   */
1.126     brouard  1777:   int iter; 
                   1778:   double a,b,d,etemp;
1.159     brouard  1779:   double fu=0,fv,fw,fx;
1.164     brouard  1780:   double ftemp=0.;
1.126     brouard  1781:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1782:   double e=0.0; 
                   1783:  
                   1784:   a=(ax < cx ? ax : cx); 
                   1785:   b=(ax > cx ? ax : cx); 
                   1786:   x=w=v=bx; 
                   1787:   fw=fv=fx=(*f)(x); 
                   1788:   for (iter=1;iter<=ITMAX;iter++) { 
                   1789:     xm=0.5*(a+b); 
                   1790:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1791:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1792:     printf(".");fflush(stdout);
                   1793:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1794: #ifdef DEBUGBRENT
1.126     brouard  1795:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1796:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1797:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1798: #endif
                   1799:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1800:       *xmin=x; 
                   1801:       return fx; 
                   1802:     } 
                   1803:     ftemp=fu;
                   1804:     if (fabs(e) > tol1) { 
                   1805:       r=(x-w)*(fx-fv); 
                   1806:       q=(x-v)*(fx-fw); 
                   1807:       p=(x-v)*q-(x-w)*r; 
                   1808:       q=2.0*(q-r); 
                   1809:       if (q > 0.0) p = -p; 
                   1810:       q=fabs(q); 
                   1811:       etemp=e; 
                   1812:       e=d; 
                   1813:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1814:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1815:       else { 
1.224     brouard  1816:                                d=p/q; 
                   1817:                                u=x+d; 
                   1818:                                if (u-a < tol2 || b-u < tol2) 
                   1819:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1820:       } 
                   1821:     } else { 
                   1822:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1823:     } 
                   1824:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1825:     fu=(*f)(u); 
                   1826:     if (fu <= fx) { 
                   1827:       if (u >= x) a=x; else b=x; 
                   1828:       SHFT(v,w,x,u) 
1.183     brouard  1829:       SHFT(fv,fw,fx,fu) 
                   1830:     } else { 
                   1831:       if (u < x) a=u; else b=u; 
                   1832:       if (fu <= fw || w == x) { 
1.224     brouard  1833:                                v=w; 
                   1834:                                w=u; 
                   1835:                                fv=fw; 
                   1836:                                fw=fu; 
1.183     brouard  1837:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1838:                                v=u; 
                   1839:                                fv=fu; 
1.183     brouard  1840:       } 
                   1841:     } 
1.126     brouard  1842:   } 
                   1843:   nrerror("Too many iterations in brent"); 
                   1844:   *xmin=x; 
                   1845:   return fx; 
                   1846: } 
                   1847: 
                   1848: /****************** mnbrak ***********************/
                   1849: 
                   1850: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1851:            double (*func)(double)) 
1.183     brouard  1852: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1853: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1854: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1855: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1856:    */
1.126     brouard  1857:   double ulim,u,r,q, dum;
                   1858:   double fu; 
1.187     brouard  1859: 
                   1860:   double scale=10.;
                   1861:   int iterscale=0;
                   1862: 
                   1863:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1864:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1865: 
                   1866: 
                   1867:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1868:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1869:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1870:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1871:   /* } */
                   1872: 
1.126     brouard  1873:   if (*fb > *fa) { 
                   1874:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1875:     SHFT(dum,*fb,*fa,dum) 
                   1876:   } 
1.126     brouard  1877:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1878:   *fc=(*func)(*cx); 
1.183     brouard  1879: #ifdef DEBUG
1.224     brouard  1880:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1881:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1882: #endif
1.224     brouard  1883:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1884:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1885:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1886:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1887:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1888:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1889:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1890:       fu=(*func)(u); 
1.163     brouard  1891: #ifdef DEBUG
                   1892:       /* f(x)=A(x-u)**2+f(u) */
                   1893:       double A, fparabu; 
                   1894:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1895:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1896:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1897:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1898:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1899:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1900:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1901:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1902: #endif 
1.184     brouard  1903: #ifdef MNBRAKORIGINAL
1.183     brouard  1904: #else
1.191     brouard  1905: /*       if (fu > *fc) { */
                   1906: /* #ifdef DEBUG */
                   1907: /*       printf("mnbrak4  fu > fc \n"); */
                   1908: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1909: /* #endif */
                   1910: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1911: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1912: /*     dum=u; /\* Shifting c and u *\/ */
                   1913: /*     u = *cx; */
                   1914: /*     *cx = dum; */
                   1915: /*     dum = fu; */
                   1916: /*     fu = *fc; */
                   1917: /*     *fc =dum; */
                   1918: /*       } else { /\* end *\/ */
                   1919: /* #ifdef DEBUG */
                   1920: /*       printf("mnbrak3  fu < fc \n"); */
                   1921: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1922: /* #endif */
                   1923: /*     dum=u; /\* Shifting c and u *\/ */
                   1924: /*     u = *cx; */
                   1925: /*     *cx = dum; */
                   1926: /*     dum = fu; */
                   1927: /*     fu = *fc; */
                   1928: /*     *fc =dum; */
                   1929: /*       } */
1.224     brouard  1930: #ifdef DEBUGMNBRAK
                   1931:                 double A, fparabu; 
                   1932:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1933:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1934:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1935:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1936: #endif
1.191     brouard  1937:       dum=u; /* Shifting c and u */
                   1938:       u = *cx;
                   1939:       *cx = dum;
                   1940:       dum = fu;
                   1941:       fu = *fc;
                   1942:       *fc =dum;
1.183     brouard  1943: #endif
1.162     brouard  1944:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1945: #ifdef DEBUG
1.224     brouard  1946:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1947:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1948: #endif
1.126     brouard  1949:       fu=(*func)(u); 
                   1950:       if (fu < *fc) { 
1.183     brouard  1951: #ifdef DEBUG
1.224     brouard  1952:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1953:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1954: #endif
                   1955:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1956:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1957: #ifdef DEBUG
                   1958:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1959: #endif
                   1960:       } 
1.162     brouard  1961:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1962: #ifdef DEBUG
1.224     brouard  1963:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1964:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1965: #endif
1.126     brouard  1966:       u=ulim; 
                   1967:       fu=(*func)(u); 
1.183     brouard  1968:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1969: #ifdef DEBUG
1.224     brouard  1970:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1971:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1972: #endif
1.126     brouard  1973:       u=(*cx)+GOLD*(*cx-*bx); 
                   1974:       fu=(*func)(u); 
1.224     brouard  1975: #ifdef DEBUG
                   1976:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1977:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1978: #endif
1.183     brouard  1979:     } /* end tests */
1.126     brouard  1980:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1981:     SHFT(*fa,*fb,*fc,fu) 
                   1982: #ifdef DEBUG
1.224     brouard  1983:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1984:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1985: #endif
                   1986:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1987: } 
                   1988: 
                   1989: /*************** linmin ************************/
1.162     brouard  1990: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1991: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1992: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1993: the value of func at the returned location p . This is actually all accomplished by calling the
                   1994: routines mnbrak and brent .*/
1.126     brouard  1995: int ncom; 
                   1996: double *pcom,*xicom;
                   1997: double (*nrfunc)(double []); 
                   1998:  
1.224     brouard  1999: #ifdef LINMINORIGINAL
1.126     brouard  2000: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2001: #else
                   2002: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2003: #endif
1.126     brouard  2004: { 
                   2005:   double brent(double ax, double bx, double cx, 
                   2006:               double (*f)(double), double tol, double *xmin); 
                   2007:   double f1dim(double x); 
                   2008:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2009:              double *fc, double (*func)(double)); 
                   2010:   int j; 
                   2011:   double xx,xmin,bx,ax; 
                   2012:   double fx,fb,fa;
1.187     brouard  2013: 
1.203     brouard  2014: #ifdef LINMINORIGINAL
                   2015: #else
                   2016:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2017: #endif
                   2018:   
1.126     brouard  2019:   ncom=n; 
                   2020:   pcom=vector(1,n); 
                   2021:   xicom=vector(1,n); 
                   2022:   nrfunc=func; 
                   2023:   for (j=1;j<=n;j++) { 
                   2024:     pcom[j]=p[j]; 
1.202     brouard  2025:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2026:   } 
1.187     brouard  2027: 
1.203     brouard  2028: #ifdef LINMINORIGINAL
                   2029:   xx=1.;
                   2030: #else
                   2031:   axs=0.0;
                   2032:   xxs=1.;
                   2033:   do{
                   2034:     xx= xxs;
                   2035: #endif
1.187     brouard  2036:     ax=0.;
                   2037:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2038:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2039:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2040:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2041:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2042:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2043:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2044: #ifdef LINMINORIGINAL
                   2045: #else
                   2046:     if (fx != fx){
1.224     brouard  2047:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2048:                        printf("|");
                   2049:                        fprintf(ficlog,"|");
1.203     brouard  2050: #ifdef DEBUGLINMIN
1.224     brouard  2051:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2052: #endif
                   2053:     }
1.224     brouard  2054:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2055: #endif
                   2056:   
1.191     brouard  2057: #ifdef DEBUGLINMIN
                   2058:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2059:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2060: #endif
1.224     brouard  2061: #ifdef LINMINORIGINAL
                   2062: #else
                   2063:        if(fb == fx){ /* Flat function in the direction */
                   2064:                xmin=xx;
                   2065:     *flat=1;
                   2066:        }else{
                   2067:     *flat=0;
                   2068: #endif
                   2069:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2070:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2071:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2072:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2073:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2074:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2075: #ifdef DEBUG
1.224     brouard  2076:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2077:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2078: #endif
                   2079: #ifdef LINMINORIGINAL
                   2080: #else
                   2081:                        }
1.126     brouard  2082: #endif
1.191     brouard  2083: #ifdef DEBUGLINMIN
                   2084:   printf("linmin end ");
1.202     brouard  2085:   fprintf(ficlog,"linmin end ");
1.191     brouard  2086: #endif
1.126     brouard  2087:   for (j=1;j<=n;j++) { 
1.203     brouard  2088: #ifdef LINMINORIGINAL
                   2089:     xi[j] *= xmin; 
                   2090: #else
                   2091: #ifdef DEBUGLINMIN
                   2092:     if(xxs <1.0)
                   2093:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2094: #endif
                   2095:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2096: #ifdef DEBUGLINMIN
                   2097:     if(xxs <1.0)
                   2098:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2099: #endif
                   2100: #endif
1.187     brouard  2101:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2102:   } 
1.191     brouard  2103: #ifdef DEBUGLINMIN
1.203     brouard  2104:   printf("\n");
1.191     brouard  2105:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2106:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2107:   for (j=1;j<=n;j++) { 
1.202     brouard  2108:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2109:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2110:     if(j % ncovmodel == 0){
1.191     brouard  2111:       printf("\n");
1.202     brouard  2112:       fprintf(ficlog,"\n");
                   2113:     }
1.191     brouard  2114:   }
1.203     brouard  2115: #else
1.191     brouard  2116: #endif
1.126     brouard  2117:   free_vector(xicom,1,n); 
                   2118:   free_vector(pcom,1,n); 
                   2119: } 
                   2120: 
                   2121: 
                   2122: /*************** powell ************************/
1.162     brouard  2123: /*
                   2124: Minimization of a function func of n variables. Input consists of an initial starting point
                   2125: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2126: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2127: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2128: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2129: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2130:  */
1.224     brouard  2131: #ifdef LINMINORIGINAL
                   2132: #else
                   2133:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2134:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2135: #endif
1.126     brouard  2136: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2137:            double (*func)(double [])) 
                   2138: { 
1.224     brouard  2139: #ifdef LINMINORIGINAL
                   2140:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2141:              double (*func)(double [])); 
1.224     brouard  2142: #else 
1.241     brouard  2143:  void linmin(double p[], double xi[], int n, double *fret,
                   2144:             double (*func)(double []),int *flat); 
1.224     brouard  2145: #endif
1.239     brouard  2146:  int i,ibig,j,jk,k; 
1.126     brouard  2147:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2148:   double directest;
1.126     brouard  2149:   double fp,fptt;
                   2150:   double *xits;
                   2151:   int niterf, itmp;
1.224     brouard  2152: #ifdef LINMINORIGINAL
                   2153: #else
                   2154: 
                   2155:   flatdir=ivector(1,n); 
                   2156:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2157: #endif
1.126     brouard  2158: 
                   2159:   pt=vector(1,n); 
                   2160:   ptt=vector(1,n); 
                   2161:   xit=vector(1,n); 
                   2162:   xits=vector(1,n); 
                   2163:   *fret=(*func)(p); 
                   2164:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2165:   rcurr_time = time(NULL);  
1.126     brouard  2166:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2167:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2168:     ibig=0; 
                   2169:     del=0.0; 
1.157     brouard  2170:     rlast_time=rcurr_time;
                   2171:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2172:     rcurr_time = time(NULL);  
                   2173:     curr_time = *localtime(&rcurr_time);
                   2174:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2175:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2176: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2177:     for (i=1;i<=n;i++) {
1.126     brouard  2178:       fprintf(ficrespow," %.12lf", p[i]);
                   2179:     }
1.239     brouard  2180:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2181:     printf("\n#model=  1      +     age ");
                   2182:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2183:     if(nagesqr==1){
1.241     brouard  2184:        printf("  + age*age  ");
                   2185:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2186:     }
                   2187:     for(j=1;j <=ncovmodel-2;j++){
                   2188:       if(Typevar[j]==0) {
                   2189:        printf("  +      V%d  ",Tvar[j]);
                   2190:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2191:       }else if(Typevar[j]==1) {
                   2192:        printf("  +    V%d*age ",Tvar[j]);
                   2193:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2194:       }else if(Typevar[j]==2) {
                   2195:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2196:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2197:       }
                   2198:     }
1.126     brouard  2199:     printf("\n");
1.239     brouard  2200: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2201: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2202:     fprintf(ficlog,"\n");
1.239     brouard  2203:     for(i=1,jk=1; i <=nlstate; i++){
                   2204:       for(k=1; k <=(nlstate+ndeath); k++){
                   2205:        if (k != i) {
                   2206:          printf("%d%d ",i,k);
                   2207:          fprintf(ficlog,"%d%d ",i,k);
                   2208:          for(j=1; j <=ncovmodel; j++){
                   2209:            printf("%12.7f ",p[jk]);
                   2210:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2211:            jk++; 
                   2212:          }
                   2213:          printf("\n");
                   2214:          fprintf(ficlog,"\n");
                   2215:        }
                   2216:       }
                   2217:     }
1.241     brouard  2218:     if(*iter <=3 && *iter >1){
1.157     brouard  2219:       tml = *localtime(&rcurr_time);
                   2220:       strcpy(strcurr,asctime(&tml));
                   2221:       rforecast_time=rcurr_time; 
1.126     brouard  2222:       itmp = strlen(strcurr);
                   2223:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2224:        strcurr[itmp-1]='\0';
1.162     brouard  2225:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2226:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2227:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2228:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2229:        forecast_time = *localtime(&rforecast_time);
                   2230:        strcpy(strfor,asctime(&forecast_time));
                   2231:        itmp = strlen(strfor);
                   2232:        if(strfor[itmp-1]=='\n')
                   2233:          strfor[itmp-1]='\0';
                   2234:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2235:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2236:       }
                   2237:     }
1.187     brouard  2238:     for (i=1;i<=n;i++) { /* For each direction i */
                   2239:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2240:       fptt=(*fret); 
                   2241: #ifdef DEBUG
1.203     brouard  2242:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2243:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2244: #endif
1.203     brouard  2245:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2246:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2247: #ifdef LINMINORIGINAL
1.188     brouard  2248:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2249: #else
                   2250:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2251:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2252: #endif
                   2253:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2254:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2255:                                /* because that direction will be replaced unless the gain del is small */
                   2256:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2257:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2258:                                /* with the new direction. */
                   2259:                                del=fabs(fptt-(*fret)); 
                   2260:                                ibig=i; 
1.126     brouard  2261:       } 
                   2262: #ifdef DEBUG
                   2263:       printf("%d %.12e",i,(*fret));
                   2264:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2265:       for (j=1;j<=n;j++) {
1.224     brouard  2266:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2267:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2268:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2269:       }
                   2270:       for(j=1;j<=n;j++) {
1.225     brouard  2271:                                printf(" p(%d)=%.12e",j,p[j]);
                   2272:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2273:       }
                   2274:       printf("\n");
                   2275:       fprintf(ficlog,"\n");
                   2276: #endif
1.187     brouard  2277:     } /* end loop on each direction i */
                   2278:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2279:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2280:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2281:       for(j=1;j<=n;j++) {
1.225     brouard  2282:                                if(flatdir[j] >0){
                   2283:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2284:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2285:                                }
                   2286:                                /* printf("\n"); */
                   2287:                                /* fprintf(ficlog,"\n"); */
                   2288:                        }
1.243     brouard  2289:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2290:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2291:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2292:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2293:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2294:       /* decreased of more than 3.84  */
                   2295:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2296:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2297:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2298:                        
1.188     brouard  2299:       /* Starting the program with initial values given by a former maximization will simply change */
                   2300:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2301:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2302:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2303: #ifdef DEBUG
                   2304:       int k[2],l;
                   2305:       k[0]=1;
                   2306:       k[1]=-1;
                   2307:       printf("Max: %.12e",(*func)(p));
                   2308:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2309:       for (j=1;j<=n;j++) {
                   2310:        printf(" %.12e",p[j]);
                   2311:        fprintf(ficlog," %.12e",p[j]);
                   2312:       }
                   2313:       printf("\n");
                   2314:       fprintf(ficlog,"\n");
                   2315:       for(l=0;l<=1;l++) {
                   2316:        for (j=1;j<=n;j++) {
                   2317:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2318:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2319:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2320:        }
                   2321:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2322:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2323:       }
                   2324: #endif
                   2325: 
1.224     brouard  2326: #ifdef LINMINORIGINAL
                   2327: #else
                   2328:       free_ivector(flatdir,1,n); 
                   2329: #endif
1.126     brouard  2330:       free_vector(xit,1,n); 
                   2331:       free_vector(xits,1,n); 
                   2332:       free_vector(ptt,1,n); 
                   2333:       free_vector(pt,1,n); 
                   2334:       return; 
1.192     brouard  2335:     } /* enough precision */ 
1.240     brouard  2336:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2337:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2338:       ptt[j]=2.0*p[j]-pt[j]; 
                   2339:       xit[j]=p[j]-pt[j]; 
                   2340:       pt[j]=p[j]; 
                   2341:     } 
1.181     brouard  2342:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2343: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2344:                if (*iter <=4) {
1.225     brouard  2345: #else
                   2346: #endif
1.224     brouard  2347: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2348: #else
1.161     brouard  2349:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2350: #endif
1.162     brouard  2351:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2352:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2353:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2354:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2355:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2356:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2357:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2358:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2359:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2360:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2361:       /* mu² and del² are equal when f3=f1 */
                   2362:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2363:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2364:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2365:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2366: #ifdef NRCORIGINAL
                   2367:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2368: #else
                   2369:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2370:       t= t- del*SQR(fp-fptt);
1.183     brouard  2371: #endif
1.202     brouard  2372:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2373: #ifdef DEBUG
1.181     brouard  2374:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2375:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2376:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2377:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2378:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2379:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2380:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2381:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2382: #endif
1.183     brouard  2383: #ifdef POWELLORIGINAL
                   2384:       if (t < 0.0) { /* Then we use it for new direction */
                   2385: #else
1.182     brouard  2386:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2387:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2388:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2389:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2390:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2391:       } 
1.181     brouard  2392:       if (directest < 0.0) { /* Then we use it for new direction */
                   2393: #endif
1.191     brouard  2394: #ifdef DEBUGLINMIN
1.234     brouard  2395:        printf("Before linmin in direction P%d-P0\n",n);
                   2396:        for (j=1;j<=n;j++) {
                   2397:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2398:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2399:          if(j % ncovmodel == 0){
                   2400:            printf("\n");
                   2401:            fprintf(ficlog,"\n");
                   2402:          }
                   2403:        }
1.224     brouard  2404: #endif
                   2405: #ifdef LINMINORIGINAL
1.234     brouard  2406:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2407: #else
1.234     brouard  2408:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2409:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2410: #endif
1.234     brouard  2411:        
1.191     brouard  2412: #ifdef DEBUGLINMIN
1.234     brouard  2413:        for (j=1;j<=n;j++) { 
                   2414:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2415:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2416:          if(j % ncovmodel == 0){
                   2417:            printf("\n");
                   2418:            fprintf(ficlog,"\n");
                   2419:          }
                   2420:        }
1.224     brouard  2421: #endif
1.234     brouard  2422:        for (j=1;j<=n;j++) { 
                   2423:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2424:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2425:        }
1.224     brouard  2426: #ifdef LINMINORIGINAL
                   2427: #else
1.234     brouard  2428:        for (j=1, flatd=0;j<=n;j++) {
                   2429:          if(flatdir[j]>0)
                   2430:            flatd++;
                   2431:        }
                   2432:        if(flatd >0){
1.255     brouard  2433:          printf("%d flat directions: ",flatd);
                   2434:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2435:          for (j=1;j<=n;j++) { 
                   2436:            if(flatdir[j]>0){
                   2437:              printf("%d ",j);
                   2438:              fprintf(ficlog,"%d ",j);
                   2439:            }
                   2440:          }
                   2441:          printf("\n");
                   2442:          fprintf(ficlog,"\n");
                   2443:        }
1.191     brouard  2444: #endif
1.234     brouard  2445:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2446:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2447:        
1.126     brouard  2448: #ifdef DEBUG
1.234     brouard  2449:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2450:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2451:        for(j=1;j<=n;j++){
                   2452:          printf(" %lf",xit[j]);
                   2453:          fprintf(ficlog," %lf",xit[j]);
                   2454:        }
                   2455:        printf("\n");
                   2456:        fprintf(ficlog,"\n");
1.126     brouard  2457: #endif
1.192     brouard  2458:       } /* end of t or directest negative */
1.224     brouard  2459: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2460: #else
1.234     brouard  2461:       } /* end if (fptt < fp)  */
1.192     brouard  2462: #endif
1.225     brouard  2463: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2464:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2465: #else
1.224     brouard  2466: #endif
1.234     brouard  2467:                } /* loop iteration */ 
1.126     brouard  2468: } 
1.234     brouard  2469:   
1.126     brouard  2470: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2471:   
1.235     brouard  2472:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2473:   {
1.235     brouard  2474:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2475:        (and selected quantitative values in nres)
                   2476:        by left multiplying the unit
1.234     brouard  2477:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2478:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2479:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2480:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2481:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2482:   /* Initial matrix pimij */
                   2483:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2484:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2485:   /*  0,                   0                  , 1} */
                   2486:   /*
                   2487:    * and after some iteration: */
                   2488:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2489:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2490:   /*  0,                   0                  , 1} */
                   2491:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2492:   /* {0.51571254859325999, 0.4842874514067399, */
                   2493:   /*  0.51326036147820708, 0.48673963852179264} */
                   2494:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2495:     
1.126     brouard  2496:   int i, ii,j,k;
1.209     brouard  2497:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2498:   /* double **matprod2(); */ /* test */
1.218     brouard  2499:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2500:   double **newm;
1.209     brouard  2501:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2502:   int ncvloop=0;
1.169     brouard  2503:   
1.209     brouard  2504:   min=vector(1,nlstate);
                   2505:   max=vector(1,nlstate);
                   2506:   meandiff=vector(1,nlstate);
                   2507: 
1.218     brouard  2508:        /* Starting with matrix unity */
1.126     brouard  2509:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2510:     for (j=1;j<=nlstate+ndeath;j++){
                   2511:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2512:     }
1.169     brouard  2513:   
                   2514:   cov[1]=1.;
                   2515:   
                   2516:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2517:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2518:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2519:     ncvloop++;
1.126     brouard  2520:     newm=savm;
                   2521:     /* Covariates have to be included here again */
1.138     brouard  2522:     cov[2]=agefin;
1.187     brouard  2523:     if(nagesqr==1)
                   2524:       cov[3]= agefin*agefin;;
1.234     brouard  2525:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2526:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2527:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2528:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2529:     }
                   2530:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2531:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2532:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2533:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2534:     }
1.237     brouard  2535:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2536:       if(Dummy[Tvar[Tage[k]]]){
                   2537:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2538:       } else{
1.235     brouard  2539:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2540:       }
1.235     brouard  2541:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2542:     }
1.237     brouard  2543:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2544:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2545:       if(Dummy[Tvard[k][1]==0]){
                   2546:        if(Dummy[Tvard[k][2]==0]){
                   2547:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2548:        }else{
                   2549:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2550:        }
                   2551:       }else{
                   2552:        if(Dummy[Tvard[k][2]==0]){
                   2553:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2554:        }else{
                   2555:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2556:        }
                   2557:       }
1.234     brouard  2558:     }
1.138     brouard  2559:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2560:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2561:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2562:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2563:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2564:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2565:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2566:     
1.126     brouard  2567:     savm=oldm;
                   2568:     oldm=newm;
1.209     brouard  2569: 
                   2570:     for(j=1; j<=nlstate; j++){
                   2571:       max[j]=0.;
                   2572:       min[j]=1.;
                   2573:     }
                   2574:     for(i=1;i<=nlstate;i++){
                   2575:       sumnew=0;
                   2576:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2577:       for(j=1; j<=nlstate; j++){ 
                   2578:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2579:        max[j]=FMAX(max[j],prlim[i][j]);
                   2580:        min[j]=FMIN(min[j],prlim[i][j]);
                   2581:       }
                   2582:     }
                   2583: 
1.126     brouard  2584:     maxmax=0.;
1.209     brouard  2585:     for(j=1; j<=nlstate; j++){
                   2586:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2587:       maxmax=FMAX(maxmax,meandiff[j]);
                   2588:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2589:     } /* j loop */
1.203     brouard  2590:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2591:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2592:     if(maxmax < ftolpl){
1.209     brouard  2593:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2594:       free_vector(min,1,nlstate);
                   2595:       free_vector(max,1,nlstate);
                   2596:       free_vector(meandiff,1,nlstate);
1.126     brouard  2597:       return prlim;
                   2598:     }
1.169     brouard  2599:   } /* age loop */
1.208     brouard  2600:     /* After some age loop it doesn't converge */
1.209     brouard  2601:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2602: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2603:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2604:   free_vector(min,1,nlstate);
                   2605:   free_vector(max,1,nlstate);
                   2606:   free_vector(meandiff,1,nlstate);
1.208     brouard  2607:   
1.169     brouard  2608:   return prlim; /* should not reach here */
1.126     brouard  2609: }
                   2610: 
1.217     brouard  2611: 
                   2612:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2613: 
1.218     brouard  2614:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2615:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2616:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2617: {
1.264   ! brouard  2618:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2619:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2620:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2621:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2622:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2623:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2624:   /* Initial matrix pimij */
                   2625:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2626:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2627:   /*  0,                   0                  , 1} */
                   2628:   /*
                   2629:    * and after some iteration: */
                   2630:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2631:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2632:   /*  0,                   0                  , 1} */
                   2633:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2634:   /* {0.51571254859325999, 0.4842874514067399, */
                   2635:   /*  0.51326036147820708, 0.48673963852179264} */
                   2636:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2637: 
                   2638:   int i, ii,j,k;
1.247     brouard  2639:   int first=0;
1.217     brouard  2640:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2641:   /* double **matprod2(); */ /* test */
                   2642:   double **out, cov[NCOVMAX+1], **bmij();
                   2643:   double **newm;
1.218     brouard  2644:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2645:   double        **oldm, **savm;  /* for use */
                   2646: 
1.217     brouard  2647:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2648:   int ncvloop=0;
                   2649:   
                   2650:   min=vector(1,nlstate);
                   2651:   max=vector(1,nlstate);
                   2652:   meandiff=vector(1,nlstate);
                   2653: 
1.218     brouard  2654:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2655:        oldm=oldms; savm=savms;
                   2656: 
                   2657:        /* Starting with matrix unity */
                   2658:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2659:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2660:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2661:     }
                   2662:   
                   2663:   cov[1]=1.;
                   2664:   
                   2665:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2666:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2667:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2668:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2669:     ncvloop++;
1.218     brouard  2670:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2671:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2672:     /* Covariates have to be included here again */
                   2673:     cov[2]=agefin;
                   2674:     if(nagesqr==1)
                   2675:       cov[3]= agefin*agefin;;
1.242     brouard  2676:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2677:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2678:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264   ! brouard  2679:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2680:     }
                   2681:     /* for (k=1; k<=cptcovn;k++) { */
                   2682:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2683:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2684:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2685:     /* } */
                   2686:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2687:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2688:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2689:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2690:     }
                   2691:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2692:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2693:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2694:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2695:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2696:       if(Dummy[Tvar[Tage[k]]]){
                   2697:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2698:       } else{
                   2699:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2700:       }
                   2701:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2702:     }
                   2703:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2704:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2705:       if(Dummy[Tvard[k][1]==0]){
                   2706:        if(Dummy[Tvard[k][2]==0]){
                   2707:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2708:        }else{
                   2709:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2710:        }
                   2711:       }else{
                   2712:        if(Dummy[Tvard[k][2]==0]){
                   2713:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2714:        }else{
                   2715:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2716:        }
                   2717:       }
1.217     brouard  2718:     }
                   2719:     
                   2720:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2721:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2722:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2723:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2724:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2725:                /* ij should be linked to the correct index of cov */
                   2726:                /* age and covariate values ij are in 'cov', but we need to pass
                   2727:                 * ij for the observed prevalence at age and status and covariate
                   2728:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2729:                 */
                   2730:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2731:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2732:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2733:     savm=oldm;
                   2734:     oldm=newm;
                   2735:     for(j=1; j<=nlstate; j++){
                   2736:       max[j]=0.;
                   2737:       min[j]=1.;
                   2738:     }
                   2739:     for(j=1; j<=nlstate; j++){ 
                   2740:       for(i=1;i<=nlstate;i++){
1.234     brouard  2741:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2742:        bprlim[i][j]= newm[i][j];
                   2743:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2744:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2745:       }
                   2746:     }
1.218     brouard  2747:                
1.217     brouard  2748:     maxmax=0.;
                   2749:     for(i=1; i<=nlstate; i++){
                   2750:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2751:       maxmax=FMAX(maxmax,meandiff[i]);
                   2752:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2753:     } /* j loop */
                   2754:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2755:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2756:     if(maxmax < ftolpl){
1.220     brouard  2757:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2758:       free_vector(min,1,nlstate);
                   2759:       free_vector(max,1,nlstate);
                   2760:       free_vector(meandiff,1,nlstate);
                   2761:       return bprlim;
                   2762:     }
                   2763:   } /* age loop */
                   2764:     /* After some age loop it doesn't converge */
1.247     brouard  2765:   if(first){
                   2766:     first=1;
                   2767:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2768: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2769:   }
                   2770:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2771: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2772:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2773:   free_vector(min,1,nlstate);
                   2774:   free_vector(max,1,nlstate);
                   2775:   free_vector(meandiff,1,nlstate);
                   2776:   
                   2777:   return bprlim; /* should not reach here */
                   2778: }
                   2779: 
1.126     brouard  2780: /*************** transition probabilities ***************/ 
                   2781: 
                   2782: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2783: {
1.138     brouard  2784:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2785:      computes the probability to be observed in state j being in state i by appying the
                   2786:      model to the ncovmodel covariates (including constant and age).
                   2787:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2788:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2789:      ncth covariate in the global vector x is given by the formula:
                   2790:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2791:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2792:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2793:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2794:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2795:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2796:   */
                   2797:   double s1, lnpijopii;
1.126     brouard  2798:   /*double t34;*/
1.164     brouard  2799:   int i,j, nc, ii, jj;
1.126     brouard  2800: 
1.223     brouard  2801:   for(i=1; i<= nlstate; i++){
                   2802:     for(j=1; j<i;j++){
                   2803:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2804:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2805:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2806:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2807:       }
                   2808:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2809:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2810:     }
                   2811:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2812:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2813:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2814:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2815:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2816:       }
                   2817:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2818:     }
                   2819:   }
1.218     brouard  2820:   
1.223     brouard  2821:   for(i=1; i<= nlstate; i++){
                   2822:     s1=0;
                   2823:     for(j=1; j<i; j++){
                   2824:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2825:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2826:     }
                   2827:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2828:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2829:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2830:     }
                   2831:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2832:     ps[i][i]=1./(s1+1.);
                   2833:     /* Computing other pijs */
                   2834:     for(j=1; j<i; j++)
                   2835:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2836:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2837:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2838:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2839:   } /* end i */
1.218     brouard  2840:   
1.223     brouard  2841:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2842:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2843:       ps[ii][jj]=0;
                   2844:       ps[ii][ii]=1;
                   2845:     }
                   2846:   }
1.218     brouard  2847:   
                   2848:   
1.223     brouard  2849:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2850:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2851:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2852:   /*   } */
                   2853:   /*   printf("\n "); */
                   2854:   /* } */
                   2855:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2856:   /*
                   2857:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2858:                goto end;*/
1.223     brouard  2859:   return ps;
1.126     brouard  2860: }
                   2861: 
1.218     brouard  2862: /*************** backward transition probabilities ***************/ 
                   2863: 
                   2864:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2865: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2866:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2867: {
1.222     brouard  2868:   /* Computes the backward probability at age agefin and covariate ij
                   2869:    * and returns in **ps as well as **bmij.
                   2870:    */
1.218     brouard  2871:   int i, ii, j,k;
1.222     brouard  2872:   
                   2873:   double **out, **pmij();
                   2874:   double sumnew=0.;
1.218     brouard  2875:   double agefin;
1.222     brouard  2876:   
                   2877:   double **dnewm, **dsavm, **doldm;
                   2878:   double **bbmij;
                   2879:   
1.218     brouard  2880:   doldm=ddoldms; /* global pointers */
1.222     brouard  2881:   dnewm=ddnewms;
                   2882:   dsavm=ddsavms;
                   2883:   
                   2884:   agefin=cov[2];
                   2885:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2886:      the observed prevalence (with this covariate ij) */
                   2887:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2888:   /* We do have the matrix Px in savm  and we need pij */
                   2889:   for (j=1;j<=nlstate+ndeath;j++){
                   2890:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2891:     for (ii=1;ii<=nlstate;ii++){
                   2892:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2893:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2894:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2895:       if(sumnew >= 1.e-10){
                   2896:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2897:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2898:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2899:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2900:        /* }else */
                   2901:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2902:       }else{
1.242     brouard  2903:        ;
                   2904:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2905:       }
                   2906:     } /*End ii */
                   2907:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2908:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2909:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2910:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2911:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2912:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2913:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2914:   for (j=1;j<=nlstate+ndeath;j++){
                   2915:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2916:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2917:     }
                   2918:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2919:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2920:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2921:   /* end bmij */
                   2922:   return ps; 
1.218     brouard  2923: }
1.217     brouard  2924: /*************** transition probabilities ***************/ 
                   2925: 
1.218     brouard  2926: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2927: {
                   2928:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2929:      computes the probability to be observed in state j being in state i by appying the
                   2930:      model to the ncovmodel covariates (including constant and age).
                   2931:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2932:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2933:      ncth covariate in the global vector x is given by the formula:
                   2934:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2935:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2936:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2937:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2938:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2939:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2940:   */
                   2941:   double s1, lnpijopii;
                   2942:   /*double t34;*/
                   2943:   int i,j, nc, ii, jj;
                   2944: 
1.234     brouard  2945:   for(i=1; i<= nlstate; i++){
                   2946:     for(j=1; j<i;j++){
                   2947:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2948:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2949:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2950:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2951:       }
                   2952:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2953:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2954:     }
                   2955:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2956:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2957:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2958:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2959:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2960:       }
                   2961:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2962:     }
                   2963:   }
                   2964:   
                   2965:   for(i=1; i<= nlstate; i++){
                   2966:     s1=0;
                   2967:     for(j=1; j<i; j++){
                   2968:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2969:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2970:     }
                   2971:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2972:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2973:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2974:     }
                   2975:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2976:     ps[i][i]=1./(s1+1.);
                   2977:     /* Computing other pijs */
                   2978:     for(j=1; j<i; j++)
                   2979:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2980:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2981:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2982:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2983:   } /* end i */
                   2984:   
                   2985:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2986:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2987:       ps[ii][jj]=0;
                   2988:       ps[ii][ii]=1;
                   2989:     }
                   2990:   }
                   2991:   /* Added for backcast */ /* Transposed matrix too */
                   2992:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2993:     s1=0.;
                   2994:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2995:       s1+=ps[ii][jj];
                   2996:     }
                   2997:     for(ii=1; ii<= nlstate; ii++){
                   2998:       ps[ii][jj]=ps[ii][jj]/s1;
                   2999:     }
                   3000:   }
                   3001:   /* Transposition */
                   3002:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3003:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3004:       s1=ps[ii][jj];
                   3005:       ps[ii][jj]=ps[jj][ii];
                   3006:       ps[jj][ii]=s1;
                   3007:     }
                   3008:   }
                   3009:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3010:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3011:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3012:   /*   } */
                   3013:   /*   printf("\n "); */
                   3014:   /* } */
                   3015:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3016:   /*
                   3017:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3018:     goto end;*/
                   3019:   return ps;
1.217     brouard  3020: }
                   3021: 
                   3022: 
1.126     brouard  3023: /**************** Product of 2 matrices ******************/
                   3024: 
1.145     brouard  3025: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3026: {
                   3027:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3028:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3029:   /* in, b, out are matrice of pointers which should have been initialized 
                   3030:      before: only the contents of out is modified. The function returns
                   3031:      a pointer to pointers identical to out */
1.145     brouard  3032:   int i, j, k;
1.126     brouard  3033:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3034:     for(k=ncolol; k<=ncoloh; k++){
                   3035:       out[i][k]=0.;
                   3036:       for(j=ncl; j<=nch; j++)
                   3037:        out[i][k] +=in[i][j]*b[j][k];
                   3038:     }
1.126     brouard  3039:   return out;
                   3040: }
                   3041: 
                   3042: 
                   3043: /************* Higher Matrix Product ***************/
                   3044: 
1.235     brouard  3045: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3046: {
1.218     brouard  3047:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3048:      'nhstepm*hstepm*stepm' months (i.e. until
                   3049:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3050:      nhstepm*hstepm matrices. 
                   3051:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3052:      (typically every 2 years instead of every month which is too big 
                   3053:      for the memory).
                   3054:      Model is determined by parameters x and covariates have to be 
                   3055:      included manually here. 
                   3056: 
                   3057:      */
                   3058: 
                   3059:   int i, j, d, h, k;
1.131     brouard  3060:   double **out, cov[NCOVMAX+1];
1.126     brouard  3061:   double **newm;
1.187     brouard  3062:   double agexact;
1.214     brouard  3063:   double agebegin, ageend;
1.126     brouard  3064: 
                   3065:   /* Hstepm could be zero and should return the unit matrix */
                   3066:   for (i=1;i<=nlstate+ndeath;i++)
                   3067:     for (j=1;j<=nlstate+ndeath;j++){
                   3068:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3069:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3070:     }
                   3071:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3072:   for(h=1; h <=nhstepm; h++){
                   3073:     for(d=1; d <=hstepm; d++){
                   3074:       newm=savm;
                   3075:       /* Covariates have to be included here again */
                   3076:       cov[1]=1.;
1.214     brouard  3077:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3078:       cov[2]=agexact;
                   3079:       if(nagesqr==1)
1.227     brouard  3080:        cov[3]= agexact*agexact;
1.235     brouard  3081:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3082:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3083:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3084:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3085:       }
                   3086:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3087:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3088:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3089:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3090:       }
                   3091:       for (k=1; k<=cptcovage;k++){
                   3092:        if(Dummy[Tvar[Tage[k]]]){
                   3093:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3094:        } else{
                   3095:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3096:        }
                   3097:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3098:       }
                   3099:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3100:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3101:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3102:       }
                   3103:       /* for (k=1; k<=cptcovn;k++)  */
                   3104:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3105:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3106:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3107:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3108:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3109:       
                   3110:       
1.126     brouard  3111:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3112:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3113:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3114:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3115:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3116:       /* if((int)age == 70){ */
                   3117:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3118:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3119:       /*         printf("%d pmmij ",i); */
                   3120:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3121:       /*           printf("%f ",pmmij[i][j]); */
                   3122:       /*         } */
                   3123:       /*         printf(" oldm "); */
                   3124:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3125:       /*           printf("%f ",oldm[i][j]); */
                   3126:       /*         } */
                   3127:       /*         printf("\n"); */
                   3128:       /*       } */
                   3129:       /* } */
1.126     brouard  3130:       savm=oldm;
                   3131:       oldm=newm;
                   3132:     }
                   3133:     for(i=1; i<=nlstate+ndeath; i++)
                   3134:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3135:                                po[i][j][h]=newm[i][j];
                   3136:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3137:       }
1.128     brouard  3138:     /*printf("h=%d ",h);*/
1.126     brouard  3139:   } /* end h */
1.218     brouard  3140:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3141:   return po;
                   3142: }
                   3143: 
1.217     brouard  3144: /************* Higher Back Matrix Product ***************/
1.218     brouard  3145: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3146: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3147: {
1.218     brouard  3148:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3149:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3150:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3151:      nhstepm*hstepm matrices.
                   3152:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3153:      (typically every 2 years instead of every month which is too big
1.217     brouard  3154:      for the memory).
1.218     brouard  3155:      Model is determined by parameters x and covariates have to be
                   3156:      included manually here.
1.217     brouard  3157: 
1.222     brouard  3158:   */
1.217     brouard  3159: 
                   3160:   int i, j, d, h, k;
                   3161:   double **out, cov[NCOVMAX+1];
                   3162:   double **newm;
                   3163:   double agexact;
                   3164:   double agebegin, ageend;
1.222     brouard  3165:   double **oldm, **savm;
1.217     brouard  3166: 
1.222     brouard  3167:   oldm=oldms;savm=savms;
1.217     brouard  3168:   /* Hstepm could be zero and should return the unit matrix */
                   3169:   for (i=1;i<=nlstate+ndeath;i++)
                   3170:     for (j=1;j<=nlstate+ndeath;j++){
                   3171:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3172:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3173:     }
                   3174:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3175:   for(h=1; h <=nhstepm; h++){
                   3176:     for(d=1; d <=hstepm; d++){
                   3177:       newm=savm;
                   3178:       /* Covariates have to be included here again */
                   3179:       cov[1]=1.;
                   3180:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3181:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3182:       cov[2]=agexact;
                   3183:       if(nagesqr==1)
1.222     brouard  3184:        cov[3]= agexact*agexact;
1.218     brouard  3185:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3186:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3187:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3188:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3189:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3190:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3191:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3192:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3193:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3194:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3195:                        
                   3196:                        
1.217     brouard  3197:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3198:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3199:       /* Careful transposed matrix */
1.222     brouard  3200:       /* age is in cov[2] */
1.218     brouard  3201:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3202:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3203:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3204:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3205:       /* if((int)age == 70){ */
                   3206:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3207:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3208:       /*         printf("%d pmmij ",i); */
                   3209:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3210:       /*           printf("%f ",pmmij[i][j]); */
                   3211:       /*         } */
                   3212:       /*         printf(" oldm "); */
                   3213:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3214:       /*           printf("%f ",oldm[i][j]); */
                   3215:       /*         } */
                   3216:       /*         printf("\n"); */
                   3217:       /*       } */
                   3218:       /* } */
                   3219:       savm=oldm;
                   3220:       oldm=newm;
                   3221:     }
                   3222:     for(i=1; i<=nlstate+ndeath; i++)
                   3223:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3224:        po[i][j][h]=newm[i][j];
                   3225:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3226:       }
                   3227:     /*printf("h=%d ",h);*/
                   3228:   } /* end h */
1.222     brouard  3229:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3230:   return po;
                   3231: }
                   3232: 
                   3233: 
1.162     brouard  3234: #ifdef NLOPT
                   3235:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3236:   double fret;
                   3237:   double *xt;
                   3238:   int j;
                   3239:   myfunc_data *d2 = (myfunc_data *) pd;
                   3240: /* xt = (p1-1); */
                   3241:   xt=vector(1,n); 
                   3242:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3243: 
                   3244:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3245:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3246:   printf("Function = %.12lf ",fret);
                   3247:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3248:   printf("\n");
                   3249:  free_vector(xt,1,n);
                   3250:   return fret;
                   3251: }
                   3252: #endif
1.126     brouard  3253: 
                   3254: /*************** log-likelihood *************/
                   3255: double func( double *x)
                   3256: {
1.226     brouard  3257:   int i, ii, j, k, mi, d, kk;
                   3258:   int ioffset=0;
                   3259:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3260:   double **out;
                   3261:   double lli; /* Individual log likelihood */
                   3262:   int s1, s2;
1.228     brouard  3263:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3264:   double bbh, survp;
                   3265:   long ipmx;
                   3266:   double agexact;
                   3267:   /*extern weight */
                   3268:   /* We are differentiating ll according to initial status */
                   3269:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3270:   /*for(i=1;i<imx;i++) 
                   3271:     printf(" %d\n",s[4][i]);
                   3272:   */
1.162     brouard  3273: 
1.226     brouard  3274:   ++countcallfunc;
1.162     brouard  3275: 
1.226     brouard  3276:   cov[1]=1.;
1.126     brouard  3277: 
1.226     brouard  3278:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3279:   ioffset=0;
1.226     brouard  3280:   if(mle==1){
                   3281:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3282:       /* Computes the values of the ncovmodel covariates of the model
                   3283:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3284:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3285:         to be observed in j being in i according to the model.
                   3286:       */
1.243     brouard  3287:       ioffset=2+nagesqr ;
1.233     brouard  3288:    /* Fixed */
1.234     brouard  3289:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3290:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3291:       }
1.226     brouard  3292:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3293:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3294:         has been calculated etc */
                   3295:       /* For an individual i, wav[i] gives the number of effective waves */
                   3296:       /* We compute the contribution to Likelihood of each effective transition
                   3297:         mw[mi][i] is real wave of the mi th effectve wave */
                   3298:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3299:         s2=s[mw[mi+1][i]][i];
                   3300:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3301:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3302:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3303:       */
                   3304:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3305:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3306:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3307:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3308:        }
                   3309:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3310:          for (j=1;j<=nlstate+ndeath;j++){
                   3311:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3312:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3313:          }
                   3314:        for(d=0; d<dh[mi][i]; d++){
                   3315:          newm=savm;
                   3316:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3317:          cov[2]=agexact;
                   3318:          if(nagesqr==1)
                   3319:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3320:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3321:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3322:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3323:          else
                   3324:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3325:          }
                   3326:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3327:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3328:          savm=oldm;
                   3329:          oldm=newm;
                   3330:        } /* end mult */
                   3331:        
                   3332:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3333:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3334:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3335:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3336:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3337:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3338:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3339:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3340:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3341:                                 * -stepm/2 to stepm/2 .
                   3342:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3343:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3344:                                 */
1.234     brouard  3345:        s1=s[mw[mi][i]][i];
                   3346:        s2=s[mw[mi+1][i]][i];
                   3347:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3348:        /* bias bh is positive if real duration
                   3349:         * is higher than the multiple of stepm and negative otherwise.
                   3350:         */
                   3351:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3352:        if( s2 > nlstate){ 
                   3353:          /* i.e. if s2 is a death state and if the date of death is known 
                   3354:             then the contribution to the likelihood is the probability to 
                   3355:             die between last step unit time and current  step unit time, 
                   3356:             which is also equal to probability to die before dh 
                   3357:             minus probability to die before dh-stepm . 
                   3358:             In version up to 0.92 likelihood was computed
                   3359:             as if date of death was unknown. Death was treated as any other
                   3360:             health state: the date of the interview describes the actual state
                   3361:             and not the date of a change in health state. The former idea was
                   3362:             to consider that at each interview the state was recorded
                   3363:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3364:             introduced the exact date of death then we should have modified
                   3365:             the contribution of an exact death to the likelihood. This new
                   3366:             contribution is smaller and very dependent of the step unit
                   3367:             stepm. It is no more the probability to die between last interview
                   3368:             and month of death but the probability to survive from last
                   3369:             interview up to one month before death multiplied by the
                   3370:             probability to die within a month. Thanks to Chris
                   3371:             Jackson for correcting this bug.  Former versions increased
                   3372:             mortality artificially. The bad side is that we add another loop
                   3373:             which slows down the processing. The difference can be up to 10%
                   3374:             lower mortality.
                   3375:          */
                   3376:          /* If, at the beginning of the maximization mostly, the
                   3377:             cumulative probability or probability to be dead is
                   3378:             constant (ie = 1) over time d, the difference is equal to
                   3379:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3380:             s1 at precedent wave, to be dead a month before current
                   3381:             wave is equal to probability, being at state s1 at
                   3382:             precedent wave, to be dead at mont of the current
                   3383:             wave. Then the observed probability (that this person died)
                   3384:             is null according to current estimated parameter. In fact,
                   3385:             it should be very low but not zero otherwise the log go to
                   3386:             infinity.
                   3387:          */
1.183     brouard  3388: /* #ifdef INFINITYORIGINAL */
                   3389: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3390: /* #else */
                   3391: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3392: /*         lli=log(mytinydouble); */
                   3393: /*       else */
                   3394: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3395: /* #endif */
1.226     brouard  3396:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3397:          
1.226     brouard  3398:        } else if  ( s2==-1 ) { /* alive */
                   3399:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3400:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3401:          /*survp += out[s1][j]; */
                   3402:          lli= log(survp);
                   3403:        }
                   3404:        else if  (s2==-4) { 
                   3405:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3406:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3407:          lli= log(survp); 
                   3408:        } 
                   3409:        else if  (s2==-5) { 
                   3410:          for (j=1,survp=0. ; j<=2; j++)  
                   3411:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3412:          lli= log(survp); 
                   3413:        } 
                   3414:        else{
                   3415:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3416:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3417:        } 
                   3418:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3419:        /*if(lli ==000.0)*/
                   3420:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3421:        ipmx +=1;
                   3422:        sw += weight[i];
                   3423:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3424:        /* if (lli < log(mytinydouble)){ */
                   3425:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3426:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3427:        /* } */
                   3428:       } /* end of wave */
                   3429:     } /* end of individual */
                   3430:   }  else if(mle==2){
                   3431:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3432:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3433:       for(mi=1; mi<= wav[i]-1; mi++){
                   3434:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3435:          for (j=1;j<=nlstate+ndeath;j++){
                   3436:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3437:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3438:          }
                   3439:        for(d=0; d<=dh[mi][i]; d++){
                   3440:          newm=savm;
                   3441:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3442:          cov[2]=agexact;
                   3443:          if(nagesqr==1)
                   3444:            cov[3]= agexact*agexact;
                   3445:          for (kk=1; kk<=cptcovage;kk++) {
                   3446:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3447:          }
                   3448:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3449:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3450:          savm=oldm;
                   3451:          oldm=newm;
                   3452:        } /* end mult */
                   3453:       
                   3454:        s1=s[mw[mi][i]][i];
                   3455:        s2=s[mw[mi+1][i]][i];
                   3456:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3457:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3458:        ipmx +=1;
                   3459:        sw += weight[i];
                   3460:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3461:       } /* end of wave */
                   3462:     } /* end of individual */
                   3463:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3464:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3465:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3466:       for(mi=1; mi<= wav[i]-1; mi++){
                   3467:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3468:          for (j=1;j<=nlstate+ndeath;j++){
                   3469:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3470:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3471:          }
                   3472:        for(d=0; d<dh[mi][i]; d++){
                   3473:          newm=savm;
                   3474:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3475:          cov[2]=agexact;
                   3476:          if(nagesqr==1)
                   3477:            cov[3]= agexact*agexact;
                   3478:          for (kk=1; kk<=cptcovage;kk++) {
                   3479:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3480:          }
                   3481:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3482:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3483:          savm=oldm;
                   3484:          oldm=newm;
                   3485:        } /* end mult */
                   3486:       
                   3487:        s1=s[mw[mi][i]][i];
                   3488:        s2=s[mw[mi+1][i]][i];
                   3489:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3490:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3491:        ipmx +=1;
                   3492:        sw += weight[i];
                   3493:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3494:       } /* end of wave */
                   3495:     } /* end of individual */
                   3496:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3497:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3498:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3499:       for(mi=1; mi<= wav[i]-1; mi++){
                   3500:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3501:          for (j=1;j<=nlstate+ndeath;j++){
                   3502:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3503:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3504:          }
                   3505:        for(d=0; d<dh[mi][i]; d++){
                   3506:          newm=savm;
                   3507:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3508:          cov[2]=agexact;
                   3509:          if(nagesqr==1)
                   3510:            cov[3]= agexact*agexact;
                   3511:          for (kk=1; kk<=cptcovage;kk++) {
                   3512:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3513:          }
1.126     brouard  3514:        
1.226     brouard  3515:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3516:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3517:          savm=oldm;
                   3518:          oldm=newm;
                   3519:        } /* end mult */
                   3520:       
                   3521:        s1=s[mw[mi][i]][i];
                   3522:        s2=s[mw[mi+1][i]][i];
                   3523:        if( s2 > nlstate){ 
                   3524:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3525:        } else if  ( s2==-1 ) { /* alive */
                   3526:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3527:            survp += out[s1][j];
                   3528:          lli= log(survp);
                   3529:        }else{
                   3530:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3531:        }
                   3532:        ipmx +=1;
                   3533:        sw += weight[i];
                   3534:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3535: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3536:       } /* end of wave */
                   3537:     } /* end of individual */
                   3538:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3539:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3540:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3541:       for(mi=1; mi<= wav[i]-1; mi++){
                   3542:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3543:          for (j=1;j<=nlstate+ndeath;j++){
                   3544:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3545:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3546:          }
                   3547:        for(d=0; d<dh[mi][i]; d++){
                   3548:          newm=savm;
                   3549:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3550:          cov[2]=agexact;
                   3551:          if(nagesqr==1)
                   3552:            cov[3]= agexact*agexact;
                   3553:          for (kk=1; kk<=cptcovage;kk++) {
                   3554:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3555:          }
1.126     brouard  3556:        
1.226     brouard  3557:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3558:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3559:          savm=oldm;
                   3560:          oldm=newm;
                   3561:        } /* end mult */
                   3562:       
                   3563:        s1=s[mw[mi][i]][i];
                   3564:        s2=s[mw[mi+1][i]][i];
                   3565:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3566:        ipmx +=1;
                   3567:        sw += weight[i];
                   3568:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3569:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3570:       } /* end of wave */
                   3571:     } /* end of individual */
                   3572:   } /* End of if */
                   3573:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3574:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3575:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3576:   return -l;
1.126     brouard  3577: }
                   3578: 
                   3579: /*************** log-likelihood *************/
                   3580: double funcone( double *x)
                   3581: {
1.228     brouard  3582:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3583:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3584:   int ioffset=0;
1.131     brouard  3585:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3586:   double **out;
                   3587:   double lli; /* Individual log likelihood */
                   3588:   double llt;
                   3589:   int s1, s2;
1.228     brouard  3590:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3591: 
1.126     brouard  3592:   double bbh, survp;
1.187     brouard  3593:   double agexact;
1.214     brouard  3594:   double agebegin, ageend;
1.126     brouard  3595:   /*extern weight */
                   3596:   /* We are differentiating ll according to initial status */
                   3597:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3598:   /*for(i=1;i<imx;i++) 
                   3599:     printf(" %d\n",s[4][i]);
                   3600:   */
                   3601:   cov[1]=1.;
                   3602: 
                   3603:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3604:   ioffset=0;
                   3605:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3606:     /* ioffset=2+nagesqr+cptcovage; */
                   3607:     ioffset=2+nagesqr;
1.232     brouard  3608:     /* Fixed */
1.224     brouard  3609:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3610:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3611:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3612:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3613: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3614: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3615: /*    cov[2+6]=covar[2][i]; V2  */
                   3616: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3617: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3618: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3619: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3620: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3621: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3622:     }
1.232     brouard  3623:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3624:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3625:     /* } */
1.231     brouard  3626:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3627:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3628:     /* } */
1.225     brouard  3629:     
1.233     brouard  3630: 
                   3631:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3632:     /* Wave varying (but not age varying) */
                   3633:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3634:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3635:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3636:       }
1.232     brouard  3637:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3638:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3639:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3640:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3641:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3642:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3643:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3644:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3645:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3646:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3647:       /* } */
1.126     brouard  3648:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3649:        for (j=1;j<=nlstate+ndeath;j++){
                   3650:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3651:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3652:        }
1.214     brouard  3653:       
                   3654:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3655:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3656:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3657:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3658:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3659:          and mw[mi+1][i]. dh depends on stepm.*/
                   3660:        newm=savm;
1.247     brouard  3661:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3662:        cov[2]=agexact;
                   3663:        if(nagesqr==1)
                   3664:          cov[3]= agexact*agexact;
                   3665:        for (kk=1; kk<=cptcovage;kk++) {
                   3666:          if(!FixedV[Tvar[Tage[kk]]])
                   3667:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3668:          else
                   3669:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3670:        }
                   3671:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3672:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3673:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3674:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3675:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3676:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3677:        savm=oldm;
                   3678:        oldm=newm;
1.126     brouard  3679:       } /* end mult */
                   3680:       
                   3681:       s1=s[mw[mi][i]][i];
                   3682:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3683:       /* if(s2==-1){ */
                   3684:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3685:       /*       /\* exit(1); *\/ */
                   3686:       /* } */
1.126     brouard  3687:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3688:       /* bias is positive if real duration
                   3689:        * is higher than the multiple of stepm and negative otherwise.
                   3690:        */
                   3691:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3692:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3693:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3694:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3695:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3696:        lli= log(survp);
1.126     brouard  3697:       }else if (mle==1){
1.242     brouard  3698:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3699:       } else if(mle==2){
1.242     brouard  3700:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3701:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3702:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3703:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3704:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3705:       } else{  /* mle=0 back to 1 */
1.242     brouard  3706:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3707:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3708:       } /* End of if */
                   3709:       ipmx +=1;
                   3710:       sw += weight[i];
                   3711:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3712:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3713:       if(globpr){
1.246     brouard  3714:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3715:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3716:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3717:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3718:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3719:          llt +=ll[k]*gipmx/gsw;
                   3720:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3721:        }
                   3722:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3723:       }
1.232     brouard  3724:        } /* end of wave */
                   3725: } /* end of individual */
                   3726: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3727: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3728: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3729: if(globpr==0){ /* First time we count the contributions and weights */
                   3730:        gipmx=ipmx;
                   3731:        gsw=sw;
                   3732: }
                   3733: return -l;
1.126     brouard  3734: }
                   3735: 
                   3736: 
                   3737: /*************** function likelione ***********/
                   3738: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3739: {
                   3740:   /* This routine should help understanding what is done with 
                   3741:      the selection of individuals/waves and
                   3742:      to check the exact contribution to the likelihood.
                   3743:      Plotting could be done.
                   3744:    */
                   3745:   int k;
                   3746: 
                   3747:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3748:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3749:     strcat(fileresilk,fileresu);
1.126     brouard  3750:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3751:       printf("Problem with resultfile: %s\n", fileresilk);
                   3752:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3753:     }
1.214     brouard  3754:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3755:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3756:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3757:     for(k=1; k<=nlstate; k++) 
                   3758:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3759:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3760:   }
                   3761: 
                   3762:   *fretone=(*funcone)(p);
                   3763:   if(*globpri !=0){
                   3764:     fclose(ficresilk);
1.205     brouard  3765:     if (mle ==0)
                   3766:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3767:     else if(mle >=1)
                   3768:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3769:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3770:     
1.208     brouard  3771:       
                   3772:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3773:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3774: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3775:     }
1.207     brouard  3776:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3777: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3778:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3779: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3780:     fflush(fichtm);
1.205     brouard  3781:   }
1.126     brouard  3782:   return;
                   3783: }
                   3784: 
                   3785: 
                   3786: /*********** Maximum Likelihood Estimation ***************/
                   3787: 
                   3788: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3789: {
1.165     brouard  3790:   int i,j, iter=0;
1.126     brouard  3791:   double **xi;
                   3792:   double fret;
                   3793:   double fretone; /* Only one call to likelihood */
                   3794:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3795: 
                   3796: #ifdef NLOPT
                   3797:   int creturn;
                   3798:   nlopt_opt opt;
                   3799:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3800:   double *lb;
                   3801:   double minf; /* the minimum objective value, upon return */
                   3802:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3803:   myfunc_data dinst, *d = &dinst;
                   3804: #endif
                   3805: 
                   3806: 
1.126     brouard  3807:   xi=matrix(1,npar,1,npar);
                   3808:   for (i=1;i<=npar;i++)
                   3809:     for (j=1;j<=npar;j++)
                   3810:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3811:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3812:   strcpy(filerespow,"POW_"); 
1.126     brouard  3813:   strcat(filerespow,fileres);
                   3814:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3815:     printf("Problem with resultfile: %s\n", filerespow);
                   3816:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3817:   }
                   3818:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3819:   for (i=1;i<=nlstate;i++)
                   3820:     for(j=1;j<=nlstate+ndeath;j++)
                   3821:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3822:   fprintf(ficrespow,"\n");
1.162     brouard  3823: #ifdef POWELL
1.126     brouard  3824:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3825: #endif
1.126     brouard  3826: 
1.162     brouard  3827: #ifdef NLOPT
                   3828: #ifdef NEWUOA
                   3829:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3830: #else
                   3831:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3832: #endif
                   3833:   lb=vector(0,npar-1);
                   3834:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3835:   nlopt_set_lower_bounds(opt, lb);
                   3836:   nlopt_set_initial_step1(opt, 0.1);
                   3837:   
                   3838:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3839:   d->function = func;
                   3840:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3841:   nlopt_set_min_objective(opt, myfunc, d);
                   3842:   nlopt_set_xtol_rel(opt, ftol);
                   3843:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3844:     printf("nlopt failed! %d\n",creturn); 
                   3845:   }
                   3846:   else {
                   3847:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3848:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3849:     iter=1; /* not equal */
                   3850:   }
                   3851:   nlopt_destroy(opt);
                   3852: #endif
1.126     brouard  3853:   free_matrix(xi,1,npar,1,npar);
                   3854:   fclose(ficrespow);
1.203     brouard  3855:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3856:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3857:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3858: 
                   3859: }
                   3860: 
                   3861: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3862: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3863: {
                   3864:   double  **a,**y,*x,pd;
1.203     brouard  3865:   /* double **hess; */
1.164     brouard  3866:   int i, j;
1.126     brouard  3867:   int *indx;
                   3868: 
                   3869:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3870:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3871:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3872:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3873:   double gompertz(double p[]);
1.203     brouard  3874:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3875: 
                   3876:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3877:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3878:   for (i=1;i<=npar;i++){
1.203     brouard  3879:     printf("%d-",i);fflush(stdout);
                   3880:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3881:    
                   3882:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3883:     
                   3884:     /*  printf(" %f ",p[i]);
                   3885:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3886:   }
                   3887:   
                   3888:   for (i=1;i<=npar;i++) {
                   3889:     for (j=1;j<=npar;j++)  {
                   3890:       if (j>i) { 
1.203     brouard  3891:        printf(".%d-%d",i,j);fflush(stdout);
                   3892:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3893:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3894:        
                   3895:        hess[j][i]=hess[i][j];    
                   3896:        /*printf(" %lf ",hess[i][j]);*/
                   3897:       }
                   3898:     }
                   3899:   }
                   3900:   printf("\n");
                   3901:   fprintf(ficlog,"\n");
                   3902: 
                   3903:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3904:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3905:   
                   3906:   a=matrix(1,npar,1,npar);
                   3907:   y=matrix(1,npar,1,npar);
                   3908:   x=vector(1,npar);
                   3909:   indx=ivector(1,npar);
                   3910:   for (i=1;i<=npar;i++)
                   3911:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3912:   ludcmp(a,npar,indx,&pd);
                   3913: 
                   3914:   for (j=1;j<=npar;j++) {
                   3915:     for (i=1;i<=npar;i++) x[i]=0;
                   3916:     x[j]=1;
                   3917:     lubksb(a,npar,indx,x);
                   3918:     for (i=1;i<=npar;i++){ 
                   3919:       matcov[i][j]=x[i];
                   3920:     }
                   3921:   }
                   3922: 
                   3923:   printf("\n#Hessian matrix#\n");
                   3924:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3925:   for (i=1;i<=npar;i++) { 
                   3926:     for (j=1;j<=npar;j++) { 
1.203     brouard  3927:       printf("%.6e ",hess[i][j]);
                   3928:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3929:     }
                   3930:     printf("\n");
                   3931:     fprintf(ficlog,"\n");
                   3932:   }
                   3933: 
1.203     brouard  3934:   /* printf("\n#Covariance matrix#\n"); */
                   3935:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3936:   /* for (i=1;i<=npar;i++) {  */
                   3937:   /*   for (j=1;j<=npar;j++) {  */
                   3938:   /*     printf("%.6e ",matcov[i][j]); */
                   3939:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3940:   /*   } */
                   3941:   /*   printf("\n"); */
                   3942:   /*   fprintf(ficlog,"\n"); */
                   3943:   /* } */
                   3944: 
1.126     brouard  3945:   /* Recompute Inverse */
1.203     brouard  3946:   /* for (i=1;i<=npar;i++) */
                   3947:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3948:   /* ludcmp(a,npar,indx,&pd); */
                   3949: 
                   3950:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3951: 
                   3952:   /* for (j=1;j<=npar;j++) { */
                   3953:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3954:   /*   x[j]=1; */
                   3955:   /*   lubksb(a,npar,indx,x); */
                   3956:   /*   for (i=1;i<=npar;i++){  */
                   3957:   /*     y[i][j]=x[i]; */
                   3958:   /*     printf("%.3e ",y[i][j]); */
                   3959:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3960:   /*   } */
                   3961:   /*   printf("\n"); */
                   3962:   /*   fprintf(ficlog,"\n"); */
                   3963:   /* } */
                   3964: 
                   3965:   /* Verifying the inverse matrix */
                   3966: #ifdef DEBUGHESS
                   3967:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3968: 
1.203     brouard  3969:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3970:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3971: 
                   3972:   for (j=1;j<=npar;j++) {
                   3973:     for (i=1;i<=npar;i++){ 
1.203     brouard  3974:       printf("%.2f ",y[i][j]);
                   3975:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3976:     }
                   3977:     printf("\n");
                   3978:     fprintf(ficlog,"\n");
                   3979:   }
1.203     brouard  3980: #endif
1.126     brouard  3981: 
                   3982:   free_matrix(a,1,npar,1,npar);
                   3983:   free_matrix(y,1,npar,1,npar);
                   3984:   free_vector(x,1,npar);
                   3985:   free_ivector(indx,1,npar);
1.203     brouard  3986:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3987: 
                   3988: 
                   3989: }
                   3990: 
                   3991: /*************** hessian matrix ****************/
                   3992: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3993: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3994:   int i;
                   3995:   int l=1, lmax=20;
1.203     brouard  3996:   double k1,k2, res, fx;
1.132     brouard  3997:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3998:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3999:   int k=0,kmax=10;
                   4000:   double l1;
                   4001: 
                   4002:   fx=func(x);
                   4003:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4004:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4005:     l1=pow(10,l);
                   4006:     delts=delt;
                   4007:     for(k=1 ; k <kmax; k=k+1){
                   4008:       delt = delta*(l1*k);
                   4009:       p2[theta]=x[theta] +delt;
1.145     brouard  4010:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4011:       p2[theta]=x[theta]-delt;
                   4012:       k2=func(p2)-fx;
                   4013:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4014:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4015:       
1.203     brouard  4016: #ifdef DEBUGHESSII
1.126     brouard  4017:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4018:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4019: #endif
                   4020:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4021:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4022:        k=kmax;
                   4023:       }
                   4024:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4025:        k=kmax; l=lmax*10;
1.126     brouard  4026:       }
                   4027:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4028:        delts=delt;
                   4029:       }
1.203     brouard  4030:     } /* End loop k */
1.126     brouard  4031:   }
                   4032:   delti[theta]=delts;
                   4033:   return res; 
                   4034:   
                   4035: }
                   4036: 
1.203     brouard  4037: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4038: {
                   4039:   int i;
1.164     brouard  4040:   int l=1, lmax=20;
1.126     brouard  4041:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4042:   double p2[MAXPARM+1];
1.203     brouard  4043:   int k, kmax=1;
                   4044:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4045: 
                   4046:   int firstime=0;
1.203     brouard  4047:   
1.126     brouard  4048:   fx=func(x);
1.203     brouard  4049:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4050:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4051:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4052:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4053:     k1=func(p2)-fx;
                   4054:   
1.203     brouard  4055:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4056:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4057:     k2=func(p2)-fx;
                   4058:   
1.203     brouard  4059:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4060:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4061:     k3=func(p2)-fx;
                   4062:   
1.203     brouard  4063:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4064:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4065:     k4=func(p2)-fx;
1.203     brouard  4066:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4067:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4068:       firstime=1;
1.203     brouard  4069:       kmax=kmax+10;
1.208     brouard  4070:     }
                   4071:     if(kmax >=10 || firstime ==1){
1.246     brouard  4072:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4073:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4074:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4075:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4076:     }
                   4077: #ifdef DEBUGHESSIJ
                   4078:     v1=hess[thetai][thetai];
                   4079:     v2=hess[thetaj][thetaj];
                   4080:     cv12=res;
                   4081:     /* Computing eigen value of Hessian matrix */
                   4082:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4083:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4084:     if ((lc2 <0) || (lc1 <0) ){
                   4085:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4086:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4087:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4088:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4089:     }
1.126     brouard  4090: #endif
                   4091:   }
                   4092:   return res;
                   4093: }
                   4094: 
1.203     brouard  4095:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4096: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4097: /* { */
                   4098: /*   int i; */
                   4099: /*   int l=1, lmax=20; */
                   4100: /*   double k1,k2,k3,k4,res,fx; */
                   4101: /*   double p2[MAXPARM+1]; */
                   4102: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4103: /*   int k=0,kmax=10; */
                   4104: /*   double l1; */
                   4105:   
                   4106: /*   fx=func(x); */
                   4107: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4108: /*     l1=pow(10,l); */
                   4109: /*     delts=delt; */
                   4110: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4111: /*       delt = delti*(l1*k); */
                   4112: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4113: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4114: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4115: /*       k1=func(p2)-fx; */
                   4116:       
                   4117: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4118: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4119: /*       k2=func(p2)-fx; */
                   4120:       
                   4121: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4122: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4123: /*       k3=func(p2)-fx; */
                   4124:       
                   4125: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4126: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4127: /*       k4=func(p2)-fx; */
                   4128: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4129: /* #ifdef DEBUGHESSIJ */
                   4130: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4131: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4132: /* #endif */
                   4133: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4134: /*     k=kmax; */
                   4135: /*       } */
                   4136: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4137: /*     k=kmax; l=lmax*10; */
                   4138: /*       } */
                   4139: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4140: /*     delts=delt; */
                   4141: /*       } */
                   4142: /*     } /\* End loop k *\/ */
                   4143: /*   } */
                   4144: /*   delti[theta]=delts; */
                   4145: /*   return res;  */
                   4146: /* } */
                   4147: 
                   4148: 
1.126     brouard  4149: /************** Inverse of matrix **************/
                   4150: void ludcmp(double **a, int n, int *indx, double *d) 
                   4151: { 
                   4152:   int i,imax,j,k; 
                   4153:   double big,dum,sum,temp; 
                   4154:   double *vv; 
                   4155:  
                   4156:   vv=vector(1,n); 
                   4157:   *d=1.0; 
                   4158:   for (i=1;i<=n;i++) { 
                   4159:     big=0.0; 
                   4160:     for (j=1;j<=n;j++) 
                   4161:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4162:     if (big == 0.0){
                   4163:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4164:       for (j=1;j<=n;j++) {
                   4165:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4166:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4167:       }
                   4168:       fflush(ficlog);
                   4169:       fclose(ficlog);
                   4170:       nrerror("Singular matrix in routine ludcmp"); 
                   4171:     }
1.126     brouard  4172:     vv[i]=1.0/big; 
                   4173:   } 
                   4174:   for (j=1;j<=n;j++) { 
                   4175:     for (i=1;i<j;i++) { 
                   4176:       sum=a[i][j]; 
                   4177:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4178:       a[i][j]=sum; 
                   4179:     } 
                   4180:     big=0.0; 
                   4181:     for (i=j;i<=n;i++) { 
                   4182:       sum=a[i][j]; 
                   4183:       for (k=1;k<j;k++) 
                   4184:        sum -= a[i][k]*a[k][j]; 
                   4185:       a[i][j]=sum; 
                   4186:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4187:        big=dum; 
                   4188:        imax=i; 
                   4189:       } 
                   4190:     } 
                   4191:     if (j != imax) { 
                   4192:       for (k=1;k<=n;k++) { 
                   4193:        dum=a[imax][k]; 
                   4194:        a[imax][k]=a[j][k]; 
                   4195:        a[j][k]=dum; 
                   4196:       } 
                   4197:       *d = -(*d); 
                   4198:       vv[imax]=vv[j]; 
                   4199:     } 
                   4200:     indx[j]=imax; 
                   4201:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4202:     if (j != n) { 
                   4203:       dum=1.0/(a[j][j]); 
                   4204:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4205:     } 
                   4206:   } 
                   4207:   free_vector(vv,1,n);  /* Doesn't work */
                   4208: ;
                   4209: } 
                   4210: 
                   4211: void lubksb(double **a, int n, int *indx, double b[]) 
                   4212: { 
                   4213:   int i,ii=0,ip,j; 
                   4214:   double sum; 
                   4215:  
                   4216:   for (i=1;i<=n;i++) { 
                   4217:     ip=indx[i]; 
                   4218:     sum=b[ip]; 
                   4219:     b[ip]=b[i]; 
                   4220:     if (ii) 
                   4221:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4222:     else if (sum) ii=i; 
                   4223:     b[i]=sum; 
                   4224:   } 
                   4225:   for (i=n;i>=1;i--) { 
                   4226:     sum=b[i]; 
                   4227:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4228:     b[i]=sum/a[i][i]; 
                   4229:   } 
                   4230: } 
                   4231: 
                   4232: void pstamp(FILE *fichier)
                   4233: {
1.196     brouard  4234:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4235: }
                   4236: 
1.253     brouard  4237: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4238: 
                   4239:   /* y=a+bx regression */
                   4240:   double   sumx = 0.0;                        /* sum of x                      */
                   4241:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4242:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4243:   double   sumy = 0.0;                        /* sum of y                      */
                   4244:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4245:   double   sume2; /* sum of square or residuals */
                   4246:   double yhat;
                   4247:   
                   4248:   double denom=0;
                   4249:   int i;
                   4250:   int ne=*no;
                   4251:   
                   4252:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4253:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4254:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4255:       continue;
                   4256:     }
                   4257:     ne=ne+1;
                   4258:     sumx  += x[i];       
                   4259:     sumx2 += x[i]*x[i];  
                   4260:     sumxy += x[i] * y[i];
                   4261:     sumy  += y[i];      
                   4262:     sumy2 += y[i]*y[i]; 
                   4263:     denom = (ne * sumx2 - sumx*sumx);
                   4264:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4265:   } 
                   4266:   
                   4267:   denom = (ne * sumx2 - sumx*sumx);
                   4268:   if (denom == 0) {
                   4269:     // vertical, slope m is infinity
                   4270:     *b = INFINITY;
                   4271:     *a = 0;
                   4272:     if (r) *r = 0;
                   4273:     return 1;
                   4274:   }
                   4275:   
                   4276:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4277:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4278:   if (r!=NULL) {
                   4279:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4280:       sqrt((sumx2 - sumx*sumx/ne) *
                   4281:           (sumy2 - sumy*sumy/ne));
                   4282:   }
                   4283:   *no=ne;
                   4284:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4285:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4286:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4287:       continue;
                   4288:     }
                   4289:     ne=ne+1;
                   4290:     yhat = y[i] - *a -*b* x[i];
                   4291:     sume2  += yhat * yhat ;       
                   4292:     
                   4293:     denom = (ne * sumx2 - sumx*sumx);
                   4294:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4295:   } 
                   4296:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4297:   *sa= *sb * sqrt(sumx2/ne);
                   4298:   
                   4299:   return 0; 
                   4300: }
                   4301: 
1.126     brouard  4302: /************ Frequencies ********************/
1.251     brouard  4303: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4304:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4305:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4306: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4307:   
1.253     brouard  4308:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4309:   int iind=0, iage=0;
                   4310:   int mi; /* Effective wave */
                   4311:   int first;
                   4312:   double ***freq; /* Frequencies */
1.253     brouard  4313:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4314:   int no;
1.226     brouard  4315:   double *meanq;
                   4316:   double **meanqt;
                   4317:   double *pp, **prop, *posprop, *pospropt;
                   4318:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4319:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4320:   double agebegin, ageend;
                   4321:     
                   4322:   pp=vector(1,nlstate);
1.251     brouard  4323:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4324:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4325:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4326:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4327:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4328:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4329:   strcpy(fileresp,"P_");
                   4330:   strcat(fileresp,fileresu);
                   4331:   /*strcat(fileresphtm,fileresu);*/
                   4332:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4333:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4334:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4335:     exit(0);
                   4336:   }
1.240     brouard  4337:   
1.226     brouard  4338:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4339:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4340:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4341:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4342:     fflush(ficlog);
                   4343:     exit(70); 
                   4344:   }
                   4345:   else{
                   4346:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4347: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4348: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4349:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4350:   }
1.237     brouard  4351:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4352:   
1.226     brouard  4353:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4354:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4355:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4356:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4357:     fflush(ficlog);
                   4358:     exit(70); 
1.240     brouard  4359:   } else{
1.226     brouard  4360:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4361: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4362: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4363:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4364:   }
1.240     brouard  4365:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4366:   
1.253     brouard  4367:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4368:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4369:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4370:   j1=0;
1.126     brouard  4371:   
1.227     brouard  4372:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4373:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4374:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4375:   
                   4376:   
1.226     brouard  4377:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4378:      reference=low_education V1=0,V2=0
                   4379:      med_educ                V1=1 V2=0, 
                   4380:      high_educ               V1=0 V2=1
                   4381:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4382:   */
1.249     brouard  4383:   dateintsum=0;
                   4384:   k2cpt=0;
                   4385: 
1.253     brouard  4386:   if(cptcoveff == 0 )
                   4387:     nl=1;  /* Constant model only */
                   4388:   else
                   4389:     nl=2;
                   4390:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4391:     if(nj==1)
                   4392:       j=0;  /* First pass for the constant */
                   4393:     else
                   4394:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4395:     first=1;
                   4396:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4397:       posproptt=0.;
                   4398:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4399:        scanf("%d", i);*/
                   4400:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4401:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4402:          for(m=iagemin; m <= iagemax+3; m++)
                   4403:            freq[i][jk][m]=0;
                   4404:       
                   4405:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4406:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4407:          prop[i][m]=0;
                   4408:        posprop[i]=0;
                   4409:        pospropt[i]=0;
                   4410:       }
                   4411:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4412:       /*   meanq[z1]+=0.; */
                   4413:       /*   for(m=1;m<=lastpass;m++){ */
                   4414:       /*       meanqt[m][z1]=0.; */
                   4415:       /*   } */
                   4416:       /* } */
                   4417:       
                   4418:       /* dateintsum=0; */
                   4419:       /* k2cpt=0; */
                   4420:       
                   4421:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4422:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4423:        bool=1;
                   4424:        if(j !=0){
                   4425:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4426:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4427:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4428:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4429:              /* } */
                   4430:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4431:                /* if(Tvaraff[z1] ==-20){ */
                   4432:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4433:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4434:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4435:                /* }else  */
                   4436:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4437:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4438:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4439:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4440:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4441:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4442:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4443:                } /* Onlyf fixed */
                   4444:              } /* end z1 */
                   4445:            } /* cptcovn > 0 */
                   4446:          } /* end any */
                   4447:        }/* end j==0 */
                   4448:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4449:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4450:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4451:            m=mw[mi][iind];
                   4452:            if(j!=0){
                   4453:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4454:                for (z1=1; z1<=cptcoveff; z1++) {
                   4455:                  if( Fixed[Tmodelind[z1]]==1){
                   4456:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4457:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4458:                                                                                      value is -1, we don't select. It differs from the 
                   4459:                                                                                      constant and age model which counts them. */
                   4460:                      bool=0; /* not selected */
                   4461:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4462:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4463:                      bool=0;
                   4464:                    }
                   4465:                  }
                   4466:                }
                   4467:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4468:            } /* end j==0 */
                   4469:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4470:            if(bool==1){
                   4471:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4472:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4473:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4474:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4475:              if(m >=firstpass && m <=lastpass){
                   4476:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4477:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4478:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4479:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4480:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4481:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4482:                if (m<lastpass) {
                   4483:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4484:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4485:                  if(s[m][iind]==-1)
                   4486:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4487:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4488:                  /* if((int)agev[m][iind] == 55) */
                   4489:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4490:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4491:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4492:                }
1.251     brouard  4493:              } /* end if between passes */  
                   4494:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4495:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4496:                k2cpt++;
                   4497:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4498:              }
1.251     brouard  4499:            }else{
                   4500:              bool=1;
                   4501:            }/* end bool 2 */
                   4502:          } /* end m */
                   4503:        } /* end bool */
                   4504:       } /* end iind = 1 to imx */
                   4505:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4506:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4507:       
                   4508:       
                   4509:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4510:       pstamp(ficresp);
                   4511:       if  (cptcoveff>0 && j!=0){
                   4512:        printf( "\n#********** Variable "); 
                   4513:        fprintf(ficresp, "\n#********** Variable "); 
                   4514:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4515:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4516:        fprintf(ficlog, "\n#********** Variable "); 
                   4517:        for (z1=1; z1<=cptcoveff; z1++){
                   4518:          if(!FixedV[Tvaraff[z1]]){
                   4519:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4520:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4521:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4522:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4523:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4524:          }else{
1.251     brouard  4525:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4526:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4527:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4528:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4529:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4530:          }
                   4531:        }
                   4532:        printf( "**********\n#");
                   4533:        fprintf(ficresp, "**********\n#");
                   4534:        fprintf(ficresphtm, "**********</h3>\n");
                   4535:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4536:        fprintf(ficlog, "**********\n");
                   4537:       }
                   4538:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4539:       for(i=1; i<=nlstate;i++) {
                   4540:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4541:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4542:       }
                   4543:       fprintf(ficresp, "\n");
                   4544:       fprintf(ficresphtm, "\n");
                   4545:       
                   4546:       /* Header of frequency table by age */
                   4547:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4548:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4549:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4550:        for(m=-1; m <=nlstate+ndeath; m++){
                   4551:          if(jk!=0 && m!=0)
                   4552:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4553:        }
1.226     brouard  4554:       }
1.251     brouard  4555:       fprintf(ficresphtmfr, "\n");
                   4556:     
                   4557:       /* For each age */
                   4558:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4559:        fprintf(ficresphtm,"<tr>");
                   4560:        if(iage==iagemax+1){
                   4561:          fprintf(ficlog,"1");
                   4562:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4563:        }else if(iage==iagemax+2){
                   4564:          fprintf(ficlog,"0");
                   4565:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4566:        }else if(iage==iagemax+3){
                   4567:          fprintf(ficlog,"Total");
                   4568:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4569:        }else{
1.240     brouard  4570:          if(first==1){
1.251     brouard  4571:            first=0;
                   4572:            printf("See log file for details...\n");
                   4573:          }
                   4574:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4575:          fprintf(ficlog,"Age %d", iage);
                   4576:        }
                   4577:        for(jk=1; jk <=nlstate ; jk++){
                   4578:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4579:            pp[jk] += freq[jk][m][iage]; 
                   4580:        }
                   4581:        for(jk=1; jk <=nlstate ; jk++){
                   4582:          for(m=-1, pos=0; m <=0 ; m++)
                   4583:            pos += freq[jk][m][iage];
                   4584:          if(pp[jk]>=1.e-10){
                   4585:            if(first==1){
                   4586:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4587:            }
                   4588:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4589:          }else{
                   4590:            if(first==1)
                   4591:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4592:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4593:          }
                   4594:        }
                   4595:       
1.251     brouard  4596:        for(jk=1; jk <=nlstate ; jk++){ 
                   4597:          /* posprop[jk]=0; */
                   4598:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4599:            pp[jk] += freq[jk][m][iage];
                   4600:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4601:       
                   4602:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4603:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4604:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4605:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4606:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4607:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4608:        }
1.251     brouard  4609:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4610:          if(pos>=1.e-5){
1.251     brouard  4611:            if(first==1)
                   4612:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4613:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4614:          }else{
                   4615:            if(first==1)
                   4616:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4617:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4618:          }
                   4619:          if( iage <= iagemax){
                   4620:            if(pos>=1.e-5){
                   4621:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
1.264   ! brouard  4622:            /* fprintf(ficresp, "%d %d %d %.5f %.0f %.0f",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)],iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta); */
        !          4623: 
1.251     brouard  4624:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4625:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4626:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4627:            }
                   4628:            else{
                   4629:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4630:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4631:            }
1.240     brouard  4632:          }
1.251     brouard  4633:          pospropt[jk] +=posprop[jk];
                   4634:        } /* end loop jk */
                   4635:        /* pospropt=0.; */
                   4636:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4637:          for(m=-1; m <=nlstate+ndeath; m++){
                   4638:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4639:              if(first==1){
                   4640:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4641:              }
1.253     brouard  4642:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4643:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4644:            }
                   4645:            if(jk!=0 && m!=0)
                   4646:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4647:          }
1.251     brouard  4648:        } /* end loop jk */
                   4649:        posproptt=0.; 
                   4650:        for(jk=1; jk <=nlstate; jk++){
                   4651:          posproptt += pospropt[jk];
                   4652:        }
                   4653:        fprintf(ficresphtmfr,"</tr>\n ");
                   4654:        if(iage <= iagemax){
                   4655:          fprintf(ficresp,"\n");
                   4656:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4657:        }
1.251     brouard  4658:        if(first==1)
                   4659:          printf("Others in log...\n");
                   4660:        fprintf(ficlog,"\n");
                   4661:       } /* end loop age iage */
                   4662:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4663:       for(jk=1; jk <=nlstate ; jk++){
                   4664:        if(posproptt < 1.e-5){
                   4665:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4666:        }else{
                   4667:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4668:        }
1.226     brouard  4669:       }
1.251     brouard  4670:       fprintf(ficresphtm,"</tr>\n");
                   4671:       fprintf(ficresphtm,"</table>\n");
                   4672:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4673:       if(posproptt < 1.e-5){
1.251     brouard  4674:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4675:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4676:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4677:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4678:        invalidvarcomb[j1]=1;
1.226     brouard  4679:       }else{
1.251     brouard  4680:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4681:        invalidvarcomb[j1]=0;
1.226     brouard  4682:       }
1.251     brouard  4683:       fprintf(ficresphtmfr,"</table>\n");
                   4684:       fprintf(ficlog,"\n");
                   4685:       if(j!=0){
                   4686:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4687:        for(i=1,jk=1; i <=nlstate; i++){
                   4688:          for(k=1; k <=(nlstate+ndeath); k++){
                   4689:            if (k != i) {
                   4690:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4691:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4692:                  if(j1==1){ /* All dummy covariates to zero */
                   4693:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4694:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4695:                    printf("%d%d ",i,k);
                   4696:                    fprintf(ficlog,"%d%d ",i,k);
                   4697:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4698:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4699:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4700:                  }
1.253     brouard  4701:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4702:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4703:                    x[iage]= (double)iage;
                   4704:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4705:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4706:                  }
                   4707:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4708:                  pstart[jk]=b;
                   4709:                  pstart[jk-1]=a;
1.252     brouard  4710:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4711:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4712:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4713:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4714:                  printf("%d%d ",i,k);
                   4715:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4716:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4717:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4718:                  ;
                   4719:                }
                   4720:                /* printf("%12.7f )", param[i][jj][k]); */
                   4721:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4722:                jk++; 
                   4723:              } /* end jj */
                   4724:            } /* end k!= i */
                   4725:          } /* end k */
                   4726:        } /* end i, jk */
                   4727:       } /* end j !=0 */
                   4728:     } /* end selected combination of covariate j1 */
                   4729:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4730:       printf("#Freqsummary: Starting values for the constants:\n");
                   4731:       fprintf(ficlog,"\n");
                   4732:       for(i=1,jk=1; i <=nlstate; i++){
                   4733:        for(k=1; k <=(nlstate+ndeath); k++){
                   4734:          if (k != i) {
                   4735:            printf("%d%d ",i,k);
                   4736:            fprintf(ficlog,"%d%d ",i,k);
                   4737:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4738:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4739:              if(jj==1){ /* Age has to be done */
                   4740:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4741:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4742:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4743:              }
                   4744:              /* printf("%12.7f )", param[i][jj][k]); */
                   4745:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4746:              jk++; 
1.250     brouard  4747:            }
1.251     brouard  4748:            printf("\n");
                   4749:            fprintf(ficlog,"\n");
1.250     brouard  4750:          }
                   4751:        }
                   4752:       }
1.251     brouard  4753:       printf("#Freqsummary\n");
                   4754:       fprintf(ficlog,"\n");
                   4755:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4756:        for(m=-1; m <=nlstate+ndeath; m++){
                   4757:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4758:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4759:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4760:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4761:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4762:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4763:          /* } */
                   4764:        }
                   4765:       } /* end loop jk */
                   4766:       
                   4767:       printf("\n");
                   4768:       fprintf(ficlog,"\n");
                   4769:     } /* end j=0 */
1.249     brouard  4770:   } /* end j */
1.252     brouard  4771: 
1.253     brouard  4772:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4773:     for(i=1, jk=1; i <=nlstate; i++){
                   4774:       for(j=1; j <=nlstate+ndeath; j++){
                   4775:        if(j!=i){
                   4776:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4777:          printf("%1d%1d",i,j);
                   4778:          fprintf(ficparo,"%1d%1d",i,j);
                   4779:          for(k=1; k<=ncovmodel;k++){
                   4780:            /*    printf(" %lf",param[i][j][k]); */
                   4781:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4782:            p[jk]=pstart[jk];
                   4783:            printf(" %f ",pstart[jk]);
                   4784:            fprintf(ficparo," %f ",pstart[jk]);
                   4785:            jk++;
                   4786:          }
                   4787:          printf("\n");
                   4788:          fprintf(ficparo,"\n");
                   4789:        }
                   4790:       }
                   4791:     }
                   4792:   } /* end mle=-2 */
1.226     brouard  4793:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4794:   
1.226     brouard  4795:   fclose(ficresp);
                   4796:   fclose(ficresphtm);
                   4797:   fclose(ficresphtmfr);
                   4798:   free_vector(meanq,1,nqfveff);
                   4799:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4800:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4801:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4802:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4803:   free_vector(pospropt,1,nlstate);
                   4804:   free_vector(posprop,1,nlstate);
1.251     brouard  4805:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4806:   free_vector(pp,1,nlstate);
                   4807:   /* End of freqsummary */
                   4808: }
1.126     brouard  4809: 
                   4810: /************ Prevalence ********************/
1.227     brouard  4811: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4812: {  
                   4813:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4814:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4815:      We still use firstpass and lastpass as another selection.
                   4816:   */
1.126     brouard  4817:  
1.227     brouard  4818:   int i, m, jk, j1, bool, z1,j, iv;
                   4819:   int mi; /* Effective wave */
                   4820:   int iage;
                   4821:   double agebegin, ageend;
                   4822: 
                   4823:   double **prop;
                   4824:   double posprop; 
                   4825:   double  y2; /* in fractional years */
                   4826:   int iagemin, iagemax;
                   4827:   int first; /** to stop verbosity which is redirected to log file */
                   4828: 
                   4829:   iagemin= (int) agemin;
                   4830:   iagemax= (int) agemax;
                   4831:   /*pp=vector(1,nlstate);*/
1.251     brouard  4832:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4833:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4834:   j1=0;
1.222     brouard  4835:   
1.227     brouard  4836:   /*j=cptcoveff;*/
                   4837:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4838:   
1.227     brouard  4839:   first=1;
                   4840:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4841:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4842:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4843:        prop[i][iage]=0.0;
                   4844:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4845:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4846:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4847:     
                   4848:     for (i=1; i<=imx; i++) { /* Each individual */
                   4849:       bool=1;
                   4850:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4851:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4852:        m=mw[mi][i];
                   4853:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4854:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4855:        for (z1=1; z1<=cptcoveff; z1++){
                   4856:          if( Fixed[Tmodelind[z1]]==1){
                   4857:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4858:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4859:              bool=0;
                   4860:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4861:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4862:              bool=0;
                   4863:            }
                   4864:        }
                   4865:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4866:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4867:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4868:          if(m >=firstpass && m <=lastpass){
                   4869:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4870:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4871:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4872:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4873:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4874:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4875:                exit(1);
                   4876:              }
                   4877:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4878:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4879:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4880:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4881:              } /* end valid statuses */ 
                   4882:            } /* end selection of dates */
                   4883:          } /* end selection of waves */
                   4884:        } /* end bool */
                   4885:       } /* end wave */
                   4886:     } /* end individual */
                   4887:     for(i=iagemin; i <= iagemax+3; i++){  
                   4888:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4889:        posprop += prop[jk][i]; 
                   4890:       } 
                   4891:       
                   4892:       for(jk=1; jk <=nlstate ; jk++){      
                   4893:        if( i <=  iagemax){ 
                   4894:          if(posprop>=1.e-5){ 
                   4895:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4896:          } else{
                   4897:            if(first==1){
                   4898:              first=0;
                   4899:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4900:            }
                   4901:          }
                   4902:        } 
                   4903:       }/* end jk */ 
                   4904:     }/* end i */ 
1.222     brouard  4905:      /*} *//* end i1 */
1.227     brouard  4906:   } /* end j1 */
1.222     brouard  4907:   
1.227     brouard  4908:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4909:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4910:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4911: }  /* End of prevalence */
1.126     brouard  4912: 
                   4913: /************* Waves Concatenation ***************/
                   4914: 
                   4915: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4916: {
                   4917:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4918:      Death is a valid wave (if date is known).
                   4919:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4920:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4921:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4922:   */
1.126     brouard  4923: 
1.224     brouard  4924:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4925:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4926:      double sum=0., jmean=0.;*/
1.224     brouard  4927:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4928:   int j, k=0,jk, ju, jl;
                   4929:   double sum=0.;
                   4930:   first=0;
1.214     brouard  4931:   firstwo=0;
1.217     brouard  4932:   firsthree=0;
1.218     brouard  4933:   firstfour=0;
1.164     brouard  4934:   jmin=100000;
1.126     brouard  4935:   jmax=-1;
                   4936:   jmean=0.;
1.224     brouard  4937: 
                   4938: /* Treating live states */
1.214     brouard  4939:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4940:     mi=0;  /* First valid wave */
1.227     brouard  4941:     mli=0; /* Last valid wave */
1.126     brouard  4942:     m=firstpass;
1.214     brouard  4943:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4944:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4945:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4946:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4947:        mw[++mi][i]=m;
                   4948:        mli=m;
1.224     brouard  4949:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4950:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4951:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4952:       }
1.227     brouard  4953:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4954: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4955:        break;
1.224     brouard  4956: #else
1.227     brouard  4957:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4958:          if(firsthree == 0){
1.262     brouard  4959:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4960:            firsthree=1;
                   4961:          }
1.262     brouard  4962:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4963:          mw[++mi][i]=m;
                   4964:          mli=m;
                   4965:        }
                   4966:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4967:          nbwarn++;
                   4968:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4969:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4970:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4971:          }
                   4972:          break;
                   4973:        }
                   4974:        break;
1.224     brouard  4975: #endif
1.227     brouard  4976:       }/* End m >= lastpass */
1.126     brouard  4977:     }/* end while */
1.224     brouard  4978: 
1.227     brouard  4979:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4980:     /* After last pass */
1.224     brouard  4981: /* Treating death states */
1.214     brouard  4982:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4983:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4984:       /* } */
1.126     brouard  4985:       mi++;    /* Death is another wave */
                   4986:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4987:       /* Only death is a correct wave */
1.126     brouard  4988:       mw[mi][i]=m;
1.257     brouard  4989:     } /* else not in a death state */
1.224     brouard  4990: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4991:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4992:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4993:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4994:          nbwarn++;
                   4995:          if(firstfiv==0){
                   4996:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4997:            firstfiv=1;
                   4998:          }else{
                   4999:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5000:          }
                   5001:        }else{ /* Death occured afer last wave potential bias */
                   5002:          nberr++;
                   5003:          if(firstwo==0){
1.257     brouard  5004:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5005:            firstwo=1;
                   5006:          }
1.257     brouard  5007:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5008:        }
1.257     brouard  5009:       }else{ /* if date of interview is unknown */
1.227     brouard  5010:        /* death is known but not confirmed by death status at any wave */
                   5011:        if(firstfour==0){
                   5012:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5013:          firstfour=1;
                   5014:        }
                   5015:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5016:       }
1.224     brouard  5017:     } /* end if date of death is known */
                   5018: #endif
                   5019:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5020:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5021:     if(mi==0){
                   5022:       nbwarn++;
                   5023:       if(first==0){
1.227     brouard  5024:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5025:        first=1;
1.126     brouard  5026:       }
                   5027:       if(first==1){
1.227     brouard  5028:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5029:       }
                   5030:     } /* end mi==0 */
                   5031:   } /* End individuals */
1.214     brouard  5032:   /* wav and mw are no more changed */
1.223     brouard  5033:        
1.214     brouard  5034:   
1.126     brouard  5035:   for(i=1; i<=imx; i++){
                   5036:     for(mi=1; mi<wav[i];mi++){
                   5037:       if (stepm <=0)
1.227     brouard  5038:        dh[mi][i]=1;
1.126     brouard  5039:       else{
1.260     brouard  5040:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5041:          if (agedc[i] < 2*AGESUP) {
                   5042:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5043:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5044:            else if(j<0){
                   5045:              nberr++;
                   5046:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5047:              j=1; /* Temporary Dangerous patch */
                   5048:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5049:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5050:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5051:            }
                   5052:            k=k+1;
                   5053:            if (j >= jmax){
                   5054:              jmax=j;
                   5055:              ijmax=i;
                   5056:            }
                   5057:            if (j <= jmin){
                   5058:              jmin=j;
                   5059:              ijmin=i;
                   5060:            }
                   5061:            sum=sum+j;
                   5062:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5063:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5064:          }
                   5065:        }
                   5066:        else{
                   5067:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5068: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5069:                                        
1.227     brouard  5070:          k=k+1;
                   5071:          if (j >= jmax) {
                   5072:            jmax=j;
                   5073:            ijmax=i;
                   5074:          }
                   5075:          else if (j <= jmin){
                   5076:            jmin=j;
                   5077:            ijmin=i;
                   5078:          }
                   5079:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5080:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5081:          if(j<0){
                   5082:            nberr++;
                   5083:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5084:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5085:          }
                   5086:          sum=sum+j;
                   5087:        }
                   5088:        jk= j/stepm;
                   5089:        jl= j -jk*stepm;
                   5090:        ju= j -(jk+1)*stepm;
                   5091:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5092:          if(jl==0){
                   5093:            dh[mi][i]=jk;
                   5094:            bh[mi][i]=0;
                   5095:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5096:                  * to avoid the price of an extra matrix product in likelihood */
                   5097:            dh[mi][i]=jk+1;
                   5098:            bh[mi][i]=ju;
                   5099:          }
                   5100:        }else{
                   5101:          if(jl <= -ju){
                   5102:            dh[mi][i]=jk;
                   5103:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5104:                                 * is higher than the multiple of stepm and negative otherwise.
                   5105:                                 */
                   5106:          }
                   5107:          else{
                   5108:            dh[mi][i]=jk+1;
                   5109:            bh[mi][i]=ju;
                   5110:          }
                   5111:          if(dh[mi][i]==0){
                   5112:            dh[mi][i]=1; /* At least one step */
                   5113:            bh[mi][i]=ju; /* At least one step */
                   5114:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5115:          }
                   5116:        } /* end if mle */
1.126     brouard  5117:       }
                   5118:     } /* end wave */
                   5119:   }
                   5120:   jmean=sum/k;
                   5121:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5122:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5123: }
1.126     brouard  5124: 
                   5125: /*********** Tricode ****************************/
1.220     brouard  5126:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5127:  {
                   5128:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5129:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5130:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5131:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5132:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5133:     */
1.130     brouard  5134: 
1.242     brouard  5135:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5136:    int modmaxcovj=0; /* Modality max of covariates j */
                   5137:    int cptcode=0; /* Modality max of covariates j */
                   5138:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5139: 
                   5140: 
1.242     brouard  5141:    /* cptcoveff=0;  */
                   5142:    /* *cptcov=0; */
1.126     brouard  5143:  
1.242     brouard  5144:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5145: 
1.242     brouard  5146:    /* Loop on covariates without age and products and no quantitative variable */
                   5147:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5148:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5149:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5150:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5151:        switch(Fixed[k]) {
                   5152:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5153:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5154:           ij=(int)(covar[Tvar[k]][i]);
                   5155:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5156:            * If product of Vn*Vm, still boolean *:
                   5157:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5158:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5159:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5160:              modality of the nth covariate of individual i. */
                   5161:           if (ij > modmaxcovj)
                   5162:             modmaxcovj=ij; 
                   5163:           else if (ij < modmincovj) 
                   5164:             modmincovj=ij; 
                   5165:           if ((ij < -1) && (ij > NCOVMAX)){
                   5166:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5167:             exit(1);
                   5168:           }else
                   5169:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5170:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5171:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5172:           /* getting the maximum value of the modality of the covariate
                   5173:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5174:              female ies 1, then modmaxcovj=1.
                   5175:           */
                   5176:         } /* end for loop on individuals i */
                   5177:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5178:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5179:         cptcode=modmaxcovj;
                   5180:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5181:         /*for (i=0; i<=cptcode; i++) {*/
                   5182:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5183:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5184:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5185:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5186:             if( j != -1){
                   5187:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5188:                                  covariate for which somebody answered excluding 
                   5189:                                  undefined. Usually 2: 0 and 1. */
                   5190:             }
                   5191:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5192:                                     covariate for which somebody answered including 
                   5193:                                     undefined. Usually 3: -1, 0 and 1. */
                   5194:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5195:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5196:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5197:                        
1.242     brouard  5198:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5199:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5200:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5201:         /* modmincovj=3; modmaxcovj = 7; */
                   5202:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5203:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5204:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5205:         /* nbcode[Tvar[j]][ij]=k; */
                   5206:         /* nbcode[Tvar[j]][1]=0; */
                   5207:         /* nbcode[Tvar[j]][2]=1; */
                   5208:         /* nbcode[Tvar[j]][3]=2; */
                   5209:         /* To be continued (not working yet). */
                   5210:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5211:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5212:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5213:             break;
                   5214:           }
                   5215:           ij++;
                   5216:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5217:           cptcode = ij; /* New max modality for covar j */
                   5218:         } /* end of loop on modality i=-1 to 1 or more */
                   5219:         break;
                   5220:        case 1: /* Testing on varying covariate, could be simple and
                   5221:                * should look at waves or product of fixed *
                   5222:                * varying. No time to test -1, assuming 0 and 1 only */
                   5223:         ij=0;
                   5224:         for(i=0; i<=1;i++){
                   5225:           nbcode[Tvar[k]][++ij]=i;
                   5226:         }
                   5227:         break;
                   5228:        default:
                   5229:         break;
                   5230:        } /* end switch */
                   5231:      } /* end dummy test */
                   5232:     
                   5233:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5234:      /*        /\*recode from 0 *\/ */
                   5235:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5236:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5237:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5238:      /*        } */
                   5239:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5240:      /*        if (ij > ncodemax[j]) { */
                   5241:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5242:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5243:      /*          break; */
                   5244:      /*        } */
                   5245:      /*   }  /\* end of loop on modality k *\/ */
                   5246:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5247:   
                   5248:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5249:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5250:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5251:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5252:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5253:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5254:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5255:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5256:   
                   5257:    ij=0;
                   5258:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5259:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5260:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5261:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5262:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5263:        /* If product not in single variable we don't print results */
                   5264:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5265:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5266:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5267:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5268:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5269:        if(Fixed[k]!=0)
                   5270:         anyvaryingduminmodel=1;
                   5271:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5272:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5273:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5274:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5275:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5276:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5277:      } 
                   5278:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5279:    /* ij--; */
                   5280:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5281:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5282:                * because they can be excluded from the model and real
                   5283:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5284:    for(j=ij+1; j<= cptcovt; j++){
                   5285:      Tvaraff[j]=0;
                   5286:      Tmodelind[j]=0;
                   5287:    }
                   5288:    for(j=ntveff+1; j<= cptcovt; j++){
                   5289:      TmodelInvind[j]=0;
                   5290:    }
                   5291:    /* To be sorted */
                   5292:    ;
                   5293:  }
1.126     brouard  5294: 
1.145     brouard  5295: 
1.126     brouard  5296: /*********** Health Expectancies ****************/
                   5297: 
1.235     brouard  5298:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5299: 
                   5300: {
                   5301:   /* Health expectancies, no variances */
1.164     brouard  5302:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5303:   int nhstepma, nstepma; /* Decreasing with age */
                   5304:   double age, agelim, hf;
                   5305:   double ***p3mat;
                   5306:   double eip;
                   5307: 
1.238     brouard  5308:   /* pstamp(ficreseij); */
1.126     brouard  5309:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5310:   fprintf(ficreseij,"# Age");
                   5311:   for(i=1; i<=nlstate;i++){
                   5312:     for(j=1; j<=nlstate;j++){
                   5313:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5314:     }
                   5315:     fprintf(ficreseij," e%1d. ",i);
                   5316:   }
                   5317:   fprintf(ficreseij,"\n");
                   5318: 
                   5319:   
                   5320:   if(estepm < stepm){
                   5321:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5322:   }
                   5323:   else  hstepm=estepm;   
                   5324:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5325:    * This is mainly to measure the difference between two models: for example
                   5326:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5327:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5328:    * progression in between and thus overestimating or underestimating according
                   5329:    * to the curvature of the survival function. If, for the same date, we 
                   5330:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5331:    * to compare the new estimate of Life expectancy with the same linear 
                   5332:    * hypothesis. A more precise result, taking into account a more precise
                   5333:    * curvature will be obtained if estepm is as small as stepm. */
                   5334: 
                   5335:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5336:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5337:      nhstepm is the number of hstepm from age to agelim 
                   5338:      nstepm is the number of stepm from age to agelin. 
                   5339:      Look at hpijx to understand the reason of that which relies in memory size
                   5340:      and note for a fixed period like estepm months */
                   5341:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5342:      survival function given by stepm (the optimization length). Unfortunately it
                   5343:      means that if the survival funtion is printed only each two years of age and if
                   5344:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5345:      results. So we changed our mind and took the option of the best precision.
                   5346:   */
                   5347:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5348: 
                   5349:   agelim=AGESUP;
                   5350:   /* If stepm=6 months */
                   5351:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5352:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5353:     
                   5354: /* nhstepm age range expressed in number of stepm */
                   5355:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5356:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5357:   /* if (stepm >= YEARM) hstepm=1;*/
                   5358:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5359:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5360: 
                   5361:   for (age=bage; age<=fage; age ++){ 
                   5362:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5363:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5364:     /* if (stepm >= YEARM) hstepm=1;*/
                   5365:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5366: 
                   5367:     /* If stepm=6 months */
                   5368:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5369:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5370:     
1.235     brouard  5371:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5372:     
                   5373:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5374:     
                   5375:     printf("%d|",(int)age);fflush(stdout);
                   5376:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5377:     
                   5378:     /* Computing expectancies */
                   5379:     for(i=1; i<=nlstate;i++)
                   5380:       for(j=1; j<=nlstate;j++)
                   5381:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5382:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5383:          
                   5384:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5385: 
                   5386:        }
                   5387: 
                   5388:     fprintf(ficreseij,"%3.0f",age );
                   5389:     for(i=1; i<=nlstate;i++){
                   5390:       eip=0;
                   5391:       for(j=1; j<=nlstate;j++){
                   5392:        eip +=eij[i][j][(int)age];
                   5393:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5394:       }
                   5395:       fprintf(ficreseij,"%9.4f", eip );
                   5396:     }
                   5397:     fprintf(ficreseij,"\n");
                   5398:     
                   5399:   }
                   5400:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5401:   printf("\n");
                   5402:   fprintf(ficlog,"\n");
                   5403:   
                   5404: }
                   5405: 
1.235     brouard  5406:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5407: 
                   5408: {
                   5409:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5410:      to initial status i, ei. .
1.126     brouard  5411:   */
                   5412:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5413:   int nhstepma, nstepma; /* Decreasing with age */
                   5414:   double age, agelim, hf;
                   5415:   double ***p3matp, ***p3matm, ***varhe;
                   5416:   double **dnewm,**doldm;
                   5417:   double *xp, *xm;
                   5418:   double **gp, **gm;
                   5419:   double ***gradg, ***trgradg;
                   5420:   int theta;
                   5421: 
                   5422:   double eip, vip;
                   5423: 
                   5424:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5425:   xp=vector(1,npar);
                   5426:   xm=vector(1,npar);
                   5427:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5428:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5429:   
                   5430:   pstamp(ficresstdeij);
                   5431:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5432:   fprintf(ficresstdeij,"# Age");
                   5433:   for(i=1; i<=nlstate;i++){
                   5434:     for(j=1; j<=nlstate;j++)
                   5435:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5436:     fprintf(ficresstdeij," e%1d. ",i);
                   5437:   }
                   5438:   fprintf(ficresstdeij,"\n");
                   5439: 
                   5440:   pstamp(ficrescveij);
                   5441:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5442:   fprintf(ficrescveij,"# Age");
                   5443:   for(i=1; i<=nlstate;i++)
                   5444:     for(j=1; j<=nlstate;j++){
                   5445:       cptj= (j-1)*nlstate+i;
                   5446:       for(i2=1; i2<=nlstate;i2++)
                   5447:        for(j2=1; j2<=nlstate;j2++){
                   5448:          cptj2= (j2-1)*nlstate+i2;
                   5449:          if(cptj2 <= cptj)
                   5450:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5451:        }
                   5452:     }
                   5453:   fprintf(ficrescveij,"\n");
                   5454:   
                   5455:   if(estepm < stepm){
                   5456:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5457:   }
                   5458:   else  hstepm=estepm;   
                   5459:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5460:    * This is mainly to measure the difference between two models: for example
                   5461:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5462:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5463:    * progression in between and thus overestimating or underestimating according
                   5464:    * to the curvature of the survival function. If, for the same date, we 
                   5465:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5466:    * to compare the new estimate of Life expectancy with the same linear 
                   5467:    * hypothesis. A more precise result, taking into account a more precise
                   5468:    * curvature will be obtained if estepm is as small as stepm. */
                   5469: 
                   5470:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5471:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5472:      nhstepm is the number of hstepm from age to agelim 
                   5473:      nstepm is the number of stepm from age to agelin. 
                   5474:      Look at hpijx to understand the reason of that which relies in memory size
                   5475:      and note for a fixed period like estepm months */
                   5476:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5477:      survival function given by stepm (the optimization length). Unfortunately it
                   5478:      means that if the survival funtion is printed only each two years of age and if
                   5479:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5480:      results. So we changed our mind and took the option of the best precision.
                   5481:   */
                   5482:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5483: 
                   5484:   /* If stepm=6 months */
                   5485:   /* nhstepm age range expressed in number of stepm */
                   5486:   agelim=AGESUP;
                   5487:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5488:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5489:   /* if (stepm >= YEARM) hstepm=1;*/
                   5490:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5491:   
                   5492:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5493:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5494:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5495:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5496:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5497:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5498: 
                   5499:   for (age=bage; age<=fage; age ++){ 
                   5500:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5501:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5502:     /* if (stepm >= YEARM) hstepm=1;*/
                   5503:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5504:                
1.126     brouard  5505:     /* If stepm=6 months */
                   5506:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5507:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5508:     
                   5509:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5510:                
1.126     brouard  5511:     /* Computing  Variances of health expectancies */
                   5512:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5513:        decrease memory allocation */
                   5514:     for(theta=1; theta <=npar; theta++){
                   5515:       for(i=1; i<=npar; i++){ 
1.222     brouard  5516:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5517:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5518:       }
1.235     brouard  5519:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5520:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5521:                        
1.126     brouard  5522:       for(j=1; j<= nlstate; j++){
1.222     brouard  5523:        for(i=1; i<=nlstate; i++){
                   5524:          for(h=0; h<=nhstepm-1; h++){
                   5525:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5526:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5527:          }
                   5528:        }
1.126     brouard  5529:       }
1.218     brouard  5530:                        
1.126     brouard  5531:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5532:        for(h=0; h<=nhstepm-1; h++){
                   5533:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5534:        }
1.126     brouard  5535:     }/* End theta */
                   5536:     
                   5537:     
                   5538:     for(h=0; h<=nhstepm-1; h++)
                   5539:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5540:        for(theta=1; theta <=npar; theta++)
                   5541:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5542:     
1.218     brouard  5543:                
1.222     brouard  5544:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5545:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5546:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5547:                
1.222     brouard  5548:     printf("%d|",(int)age);fflush(stdout);
                   5549:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5550:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5551:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5552:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5553:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5554:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5555:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5556:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5557:       }
                   5558:     }
1.218     brouard  5559:                
1.126     brouard  5560:     /* Computing expectancies */
1.235     brouard  5561:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5562:     for(i=1; i<=nlstate;i++)
                   5563:       for(j=1; j<=nlstate;j++)
1.222     brouard  5564:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5565:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5566:                                        
1.222     brouard  5567:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5568:                                        
1.222     brouard  5569:        }
1.218     brouard  5570:                
1.126     brouard  5571:     fprintf(ficresstdeij,"%3.0f",age );
                   5572:     for(i=1; i<=nlstate;i++){
                   5573:       eip=0.;
                   5574:       vip=0.;
                   5575:       for(j=1; j<=nlstate;j++){
1.222     brouard  5576:        eip += eij[i][j][(int)age];
                   5577:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5578:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5579:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5580:       }
                   5581:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5582:     }
                   5583:     fprintf(ficresstdeij,"\n");
1.218     brouard  5584:                
1.126     brouard  5585:     fprintf(ficrescveij,"%3.0f",age );
                   5586:     for(i=1; i<=nlstate;i++)
                   5587:       for(j=1; j<=nlstate;j++){
1.222     brouard  5588:        cptj= (j-1)*nlstate+i;
                   5589:        for(i2=1; i2<=nlstate;i2++)
                   5590:          for(j2=1; j2<=nlstate;j2++){
                   5591:            cptj2= (j2-1)*nlstate+i2;
                   5592:            if(cptj2 <= cptj)
                   5593:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5594:          }
1.126     brouard  5595:       }
                   5596:     fprintf(ficrescveij,"\n");
1.218     brouard  5597:                
1.126     brouard  5598:   }
                   5599:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5600:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5601:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5602:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5603:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5604:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5605:   printf("\n");
                   5606:   fprintf(ficlog,"\n");
1.218     brouard  5607:        
1.126     brouard  5608:   free_vector(xm,1,npar);
                   5609:   free_vector(xp,1,npar);
                   5610:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5611:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5612:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5613: }
1.218     brouard  5614:  
1.126     brouard  5615: /************ Variance ******************/
1.235     brouard  5616:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5617:  {
                   5618:    /* Variance of health expectancies */
                   5619:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5620:    /* double **newm;*/
                   5621:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5622:   
                   5623:    /* int movingaverage(); */
                   5624:    double **dnewm,**doldm;
                   5625:    double **dnewmp,**doldmp;
                   5626:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5627:    int k;
                   5628:    double *xp;
                   5629:    double **gp, **gm;  /* for var eij */
                   5630:    double ***gradg, ***trgradg; /*for var eij */
                   5631:    double **gradgp, **trgradgp; /* for var p point j */
                   5632:    double *gpp, *gmp; /* for var p point j */
                   5633:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5634:    double ***p3mat;
                   5635:    double age,agelim, hf;
                   5636:    /* double ***mobaverage; */
                   5637:    int theta;
                   5638:    char digit[4];
                   5639:    char digitp[25];
                   5640: 
                   5641:    char fileresprobmorprev[FILENAMELENGTH];
                   5642: 
                   5643:    if(popbased==1){
                   5644:      if(mobilav!=0)
                   5645:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5646:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5647:    }
                   5648:    else 
                   5649:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5650: 
1.218     brouard  5651:    /* if (mobilav!=0) { */
                   5652:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5653:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5654:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5655:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5656:    /*   } */
                   5657:    /* } */
                   5658: 
                   5659:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5660:    sprintf(digit,"%-d",ij);
                   5661:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5662:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5663:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5664:    strcat(fileresprobmorprev,fileresu);
                   5665:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5666:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5667:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5668:    }
                   5669:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5670:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5671:    pstamp(ficresprobmorprev);
                   5672:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5673:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5674:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5675:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5676:    }
                   5677:    for(j=1;j<=cptcoveff;j++) 
                   5678:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5679:    fprintf(ficresprobmorprev,"\n");
                   5680: 
1.218     brouard  5681:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5682:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5683:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5684:      for(i=1; i<=nlstate;i++)
                   5685:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5686:    }  
                   5687:    fprintf(ficresprobmorprev,"\n");
                   5688:   
                   5689:    fprintf(ficgp,"\n# Routine varevsij");
                   5690:    fprintf(ficgp,"\nunset title \n");
                   5691:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5692:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5693:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5694:    /*   } */
                   5695:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5696:    pstamp(ficresvij);
                   5697:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5698:    if(popbased==1)
                   5699:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5700:    else
                   5701:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5702:    fprintf(ficresvij,"# Age");
                   5703:    for(i=1; i<=nlstate;i++)
                   5704:      for(j=1; j<=nlstate;j++)
                   5705:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5706:    fprintf(ficresvij,"\n");
                   5707: 
                   5708:    xp=vector(1,npar);
                   5709:    dnewm=matrix(1,nlstate,1,npar);
                   5710:    doldm=matrix(1,nlstate,1,nlstate);
                   5711:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5712:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5713: 
                   5714:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5715:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5716:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5717:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5718:   
1.218     brouard  5719:    if(estepm < stepm){
                   5720:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5721:    }
                   5722:    else  hstepm=estepm;   
                   5723:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5724:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5725:       nhstepm is the number of hstepm from age to agelim 
                   5726:       nstepm is the number of stepm from age to agelim. 
                   5727:       Look at function hpijx to understand why because of memory size limitations, 
                   5728:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5729:       survival function given by stepm (the optimization length). Unfortunately it
                   5730:       means that if the survival funtion is printed every two years of age and if
                   5731:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5732:       results. So we changed our mind and took the option of the best precision.
                   5733:    */
                   5734:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5735:    agelim = AGESUP;
                   5736:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5737:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5738:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5739:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5740:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5741:      gp=matrix(0,nhstepm,1,nlstate);
                   5742:      gm=matrix(0,nhstepm,1,nlstate);
                   5743:                
                   5744:                
                   5745:      for(theta=1; theta <=npar; theta++){
                   5746:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5747:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5748:        }
                   5749:                        
1.242     brouard  5750:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5751:                        
                   5752:        if (popbased==1) {
                   5753:         if(mobilav ==0){
                   5754:           for(i=1; i<=nlstate;i++)
                   5755:             prlim[i][i]=probs[(int)age][i][ij];
                   5756:         }else{ /* mobilav */ 
                   5757:           for(i=1; i<=nlstate;i++)
                   5758:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5759:         }
                   5760:        }
                   5761:                        
1.235     brouard  5762:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5763:        for(j=1; j<= nlstate; j++){
                   5764:         for(h=0; h<=nhstepm; h++){
                   5765:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5766:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5767:         }
                   5768:        }
                   5769:        /* Next for computing probability of death (h=1 means
                   5770:          computed over hstepm matrices product = hstepm*stepm months) 
                   5771:          as a weighted average of prlim.
                   5772:        */
                   5773:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5774:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5775:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5776:        }    
                   5777:        /* end probability of death */
                   5778:                        
                   5779:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5780:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5781:                        
1.242     brouard  5782:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5783:                        
                   5784:        if (popbased==1) {
                   5785:         if(mobilav ==0){
                   5786:           for(i=1; i<=nlstate;i++)
                   5787:             prlim[i][i]=probs[(int)age][i][ij];
                   5788:         }else{ /* mobilav */ 
                   5789:           for(i=1; i<=nlstate;i++)
                   5790:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5791:         }
                   5792:        }
                   5793:                        
1.235     brouard  5794:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5795:                        
                   5796:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5797:         for(h=0; h<=nhstepm; h++){
                   5798:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5799:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5800:         }
                   5801:        }
                   5802:        /* This for computing probability of death (h=1 means
                   5803:          computed over hstepm matrices product = hstepm*stepm months) 
                   5804:          as a weighted average of prlim.
                   5805:        */
                   5806:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5807:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5808:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5809:        }    
                   5810:        /* end probability of death */
                   5811:                        
                   5812:        for(j=1; j<= nlstate; j++) /* vareij */
                   5813:         for(h=0; h<=nhstepm; h++){
                   5814:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5815:         }
                   5816:                        
                   5817:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5818:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5819:        }
                   5820:                        
                   5821:      } /* End theta */
                   5822:                
                   5823:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5824:                
                   5825:      for(h=0; h<=nhstepm; h++) /* veij */
                   5826:        for(j=1; j<=nlstate;j++)
                   5827:         for(theta=1; theta <=npar; theta++)
                   5828:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5829:                
                   5830:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5831:        for(theta=1; theta <=npar; theta++)
                   5832:         trgradgp[j][theta]=gradgp[theta][j];
                   5833:                
                   5834:                
                   5835:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5836:      for(i=1;i<=nlstate;i++)
                   5837:        for(j=1;j<=nlstate;j++)
                   5838:         vareij[i][j][(int)age] =0.;
                   5839:                
                   5840:      for(h=0;h<=nhstepm;h++){
                   5841:        for(k=0;k<=nhstepm;k++){
                   5842:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5843:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5844:         for(i=1;i<=nlstate;i++)
                   5845:           for(j=1;j<=nlstate;j++)
                   5846:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5847:        }
                   5848:      }
                   5849:                
                   5850:      /* pptj */
                   5851:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5852:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5853:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5854:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5855:         varppt[j][i]=doldmp[j][i];
                   5856:      /* end ppptj */
                   5857:      /*  x centered again */
                   5858:                
1.242     brouard  5859:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5860:                
                   5861:      if (popbased==1) {
                   5862:        if(mobilav ==0){
                   5863:         for(i=1; i<=nlstate;i++)
                   5864:           prlim[i][i]=probs[(int)age][i][ij];
                   5865:        }else{ /* mobilav */ 
                   5866:         for(i=1; i<=nlstate;i++)
                   5867:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5868:        }
                   5869:      }
                   5870:                
                   5871:      /* This for computing probability of death (h=1 means
                   5872:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5873:        as a weighted average of prlim.
                   5874:      */
1.235     brouard  5875:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5876:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5877:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5878:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5879:      }    
                   5880:      /* end probability of death */
                   5881:                
                   5882:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5883:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5884:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5885:        for(i=1; i<=nlstate;i++){
                   5886:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5887:        }
                   5888:      } 
                   5889:      fprintf(ficresprobmorprev,"\n");
                   5890:                
                   5891:      fprintf(ficresvij,"%.0f ",age );
                   5892:      for(i=1; i<=nlstate;i++)
                   5893:        for(j=1; j<=nlstate;j++){
                   5894:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5895:        }
                   5896:      fprintf(ficresvij,"\n");
                   5897:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5898:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5899:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5900:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5901:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5902:    } /* End age */
                   5903:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5904:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5905:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5906:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5907:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5908:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5909:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5910:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5911:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5912:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5913:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5914:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5915:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5916:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5917:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5918:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5919:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5920:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5921:     */
1.218     brouard  5922:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5923:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5924: 
1.218     brouard  5925:    free_vector(xp,1,npar);
                   5926:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5927:    free_matrix(dnewm,1,nlstate,1,npar);
                   5928:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5929:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5930:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5931:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5932:    fclose(ficresprobmorprev);
                   5933:    fflush(ficgp);
                   5934:    fflush(fichtm); 
                   5935:  }  /* end varevsij */
1.126     brouard  5936: 
                   5937: /************ Variance of prevlim ******************/
1.235     brouard  5938:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5939: {
1.205     brouard  5940:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5941:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5942: 
1.126     brouard  5943:   double **dnewm,**doldm;
                   5944:   int i, j, nhstepm, hstepm;
                   5945:   double *xp;
                   5946:   double *gp, *gm;
                   5947:   double **gradg, **trgradg;
1.208     brouard  5948:   double **mgm, **mgp;
1.126     brouard  5949:   double age,agelim;
                   5950:   int theta;
                   5951:   
                   5952:   pstamp(ficresvpl);
                   5953:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5954:   fprintf(ficresvpl,"# Age ");
                   5955:   if(nresult >=1)
                   5956:     fprintf(ficresvpl," Result# ");
1.126     brouard  5957:   for(i=1; i<=nlstate;i++)
                   5958:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5959:   fprintf(ficresvpl,"\n");
                   5960: 
                   5961:   xp=vector(1,npar);
                   5962:   dnewm=matrix(1,nlstate,1,npar);
                   5963:   doldm=matrix(1,nlstate,1,nlstate);
                   5964:   
                   5965:   hstepm=1*YEARM; /* Every year of age */
                   5966:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5967:   agelim = AGESUP;
                   5968:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5969:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5970:     if (stepm >= YEARM) hstepm=1;
                   5971:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5972:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5973:     mgp=matrix(1,npar,1,nlstate);
                   5974:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5975:     gp=vector(1,nlstate);
                   5976:     gm=vector(1,nlstate);
                   5977: 
                   5978:     for(theta=1; theta <=npar; theta++){
                   5979:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5980:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5981:       }
1.209     brouard  5982:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5983:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5984:       else
1.235     brouard  5985:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5986:       for(i=1;i<=nlstate;i++){
1.126     brouard  5987:        gp[i] = prlim[i][i];
1.208     brouard  5988:        mgp[theta][i] = prlim[i][i];
                   5989:       }
1.126     brouard  5990:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5991:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5992:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5993:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5994:       else
1.235     brouard  5995:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5996:       for(i=1;i<=nlstate;i++){
1.126     brouard  5997:        gm[i] = prlim[i][i];
1.208     brouard  5998:        mgm[theta][i] = prlim[i][i];
                   5999:       }
1.126     brouard  6000:       for(i=1;i<=nlstate;i++)
                   6001:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6002:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6003:     } /* End theta */
                   6004: 
                   6005:     trgradg =matrix(1,nlstate,1,npar);
                   6006: 
                   6007:     for(j=1; j<=nlstate;j++)
                   6008:       for(theta=1; theta <=npar; theta++)
                   6009:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6010:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6011:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6012:     /*   for(j=1; j<=nlstate;j++){ */
                   6013:     /*         printf(" %d ",j); */
                   6014:     /*         for(theta=1; theta <=npar; theta++) */
                   6015:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6016:     /*         printf("\n "); */
                   6017:     /*   } */
                   6018:     /* } */
                   6019:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6020:     /*   printf("\n gradg %d ",(int)age); */
                   6021:     /*   for(j=1; j<=nlstate;j++){ */
                   6022:     /*         printf("%d ",j); */
                   6023:     /*         for(theta=1; theta <=npar; theta++) */
                   6024:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6025:     /*         printf("\n "); */
                   6026:     /*   } */
                   6027:     /* } */
1.126     brouard  6028: 
                   6029:     for(i=1;i<=nlstate;i++)
                   6030:       varpl[i][(int)age] =0.;
1.209     brouard  6031:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6032:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6033:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6034:     }else{
1.126     brouard  6035:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6036:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6037:     }
1.126     brouard  6038:     for(i=1;i<=nlstate;i++)
                   6039:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6040: 
                   6041:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6042:     if(nresult >=1)
                   6043:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6044:     for(i=1; i<=nlstate;i++)
                   6045:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6046:     fprintf(ficresvpl,"\n");
                   6047:     free_vector(gp,1,nlstate);
                   6048:     free_vector(gm,1,nlstate);
1.208     brouard  6049:     free_matrix(mgm,1,npar,1,nlstate);
                   6050:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6051:     free_matrix(gradg,1,npar,1,nlstate);
                   6052:     free_matrix(trgradg,1,nlstate,1,npar);
                   6053:   } /* End age */
                   6054: 
                   6055:   free_vector(xp,1,npar);
                   6056:   free_matrix(doldm,1,nlstate,1,npar);
                   6057:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6058: 
                   6059: }
                   6060: 
                   6061: /************ Variance of one-step probabilities  ******************/
                   6062: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6063:  {
                   6064:    int i, j=0,  k1, l1, tj;
                   6065:    int k2, l2, j1,  z1;
                   6066:    int k=0, l;
                   6067:    int first=1, first1, first2;
                   6068:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6069:    double **dnewm,**doldm;
                   6070:    double *xp;
                   6071:    double *gp, *gm;
                   6072:    double **gradg, **trgradg;
                   6073:    double **mu;
                   6074:    double age, cov[NCOVMAX+1];
                   6075:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6076:    int theta;
                   6077:    char fileresprob[FILENAMELENGTH];
                   6078:    char fileresprobcov[FILENAMELENGTH];
                   6079:    char fileresprobcor[FILENAMELENGTH];
                   6080:    double ***varpij;
                   6081: 
                   6082:    strcpy(fileresprob,"PROB_"); 
                   6083:    strcat(fileresprob,fileres);
                   6084:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6085:      printf("Problem with resultfile: %s\n", fileresprob);
                   6086:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6087:    }
                   6088:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6089:    strcat(fileresprobcov,fileresu);
                   6090:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6091:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6092:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6093:    }
                   6094:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6095:    strcat(fileresprobcor,fileresu);
                   6096:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6097:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6098:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6099:    }
                   6100:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6101:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6102:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6103:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6104:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6105:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6106:    pstamp(ficresprob);
                   6107:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6108:    fprintf(ficresprob,"# Age");
                   6109:    pstamp(ficresprobcov);
                   6110:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6111:    fprintf(ficresprobcov,"# Age");
                   6112:    pstamp(ficresprobcor);
                   6113:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6114:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6115: 
                   6116: 
1.222     brouard  6117:    for(i=1; i<=nlstate;i++)
                   6118:      for(j=1; j<=(nlstate+ndeath);j++){
                   6119:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6120:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6121:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6122:      }  
                   6123:    /* fprintf(ficresprob,"\n");
                   6124:       fprintf(ficresprobcov,"\n");
                   6125:       fprintf(ficresprobcor,"\n");
                   6126:    */
                   6127:    xp=vector(1,npar);
                   6128:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6129:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6130:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6131:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6132:    first=1;
                   6133:    fprintf(ficgp,"\n# Routine varprob");
                   6134:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6135:    fprintf(fichtm,"\n");
                   6136: 
                   6137:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6138:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6139:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6140: and drawn. It helps understanding how is the covariance between two incidences.\
                   6141:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6142:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6143: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6144: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6145: standard deviations wide on each axis. <br>\
                   6146:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6147:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6148: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6149: 
1.222     brouard  6150:    cov[1]=1;
                   6151:    /* tj=cptcoveff; */
1.225     brouard  6152:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6153:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6154:    j1=0;
1.224     brouard  6155:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6156:      if  (cptcovn>0) {
                   6157:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6158:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6159:        fprintf(ficresprob, "**********\n#\n");
                   6160:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6161:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6162:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6163:                        
1.222     brouard  6164:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6165:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6166:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6167:                        
                   6168:                        
1.222     brouard  6169:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6170:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6171:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6172:                        
1.222     brouard  6173:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6174:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6175:        fprintf(ficresprobcor, "**********\n#");    
                   6176:        if(invalidvarcomb[j1]){
                   6177:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6178:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6179:         continue;
                   6180:        }
                   6181:      }
                   6182:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6183:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6184:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6185:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6186:      for (age=bage; age<=fage; age ++){ 
                   6187:        cov[2]=age;
                   6188:        if(nagesqr==1)
                   6189:         cov[3]= age*age;
                   6190:        for (k=1; k<=cptcovn;k++) {
                   6191:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6192:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6193:                                                                    * 1  1 1 1 1
                   6194:                                                                    * 2  2 1 1 1
                   6195:                                                                    * 3  1 2 1 1
                   6196:                                                                    */
                   6197:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6198:        }
                   6199:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6200:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6201:        for (k=1; k<=cptcovprod;k++)
                   6202:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6203:                        
                   6204:                        
1.222     brouard  6205:        for(theta=1; theta <=npar; theta++){
                   6206:         for(i=1; i<=npar; i++)
                   6207:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6208:                                
1.222     brouard  6209:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6210:                                
1.222     brouard  6211:         k=0;
                   6212:         for(i=1; i<= (nlstate); i++){
                   6213:           for(j=1; j<=(nlstate+ndeath);j++){
                   6214:             k=k+1;
                   6215:             gp[k]=pmmij[i][j];
                   6216:           }
                   6217:         }
1.220     brouard  6218:                                
1.222     brouard  6219:         for(i=1; i<=npar; i++)
                   6220:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6221:                                
1.222     brouard  6222:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6223:         k=0;
                   6224:         for(i=1; i<=(nlstate); i++){
                   6225:           for(j=1; j<=(nlstate+ndeath);j++){
                   6226:             k=k+1;
                   6227:             gm[k]=pmmij[i][j];
                   6228:           }
                   6229:         }
1.220     brouard  6230:                                
1.222     brouard  6231:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6232:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6233:        }
1.126     brouard  6234: 
1.222     brouard  6235:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6236:         for(theta=1; theta <=npar; theta++)
                   6237:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6238:                        
1.222     brouard  6239:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6240:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6241:                        
1.222     brouard  6242:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6243:                        
1.222     brouard  6244:        k=0;
                   6245:        for(i=1; i<=(nlstate); i++){
                   6246:         for(j=1; j<=(nlstate+ndeath);j++){
                   6247:           k=k+1;
                   6248:           mu[k][(int) age]=pmmij[i][j];
                   6249:         }
                   6250:        }
                   6251:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6252:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6253:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6254:                        
1.222     brouard  6255:        /*printf("\n%d ",(int)age);
                   6256:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6257:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6258:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6259:         }*/
1.220     brouard  6260:                        
1.222     brouard  6261:        fprintf(ficresprob,"\n%d ",(int)age);
                   6262:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6263:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6264:                        
1.222     brouard  6265:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6266:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6267:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6268:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6269:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6270:        }
                   6271:        i=0;
                   6272:        for (k=1; k<=(nlstate);k++){
                   6273:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6274:           i++;
                   6275:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6276:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6277:           for (j=1; j<=i;j++){
                   6278:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6279:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6280:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6281:           }
                   6282:         }
                   6283:        }/* end of loop for state */
                   6284:      } /* end of loop for age */
                   6285:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6286:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6287:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6288:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6289:     
                   6290:      /* Confidence intervalle of pij  */
                   6291:      /*
                   6292:        fprintf(ficgp,"\nunset parametric;unset label");
                   6293:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6294:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6295:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6296:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6297:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6298:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6299:      */
                   6300:                
                   6301:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6302:      first1=1;first2=2;
                   6303:      for (k2=1; k2<=(nlstate);k2++){
                   6304:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6305:         if(l2==k2) continue;
                   6306:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6307:         for (k1=1; k1<=(nlstate);k1++){
                   6308:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6309:             if(l1==k1) continue;
                   6310:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6311:             if(i<=j) continue;
                   6312:             for (age=bage; age<=fage; age ++){ 
                   6313:               if ((int)age %5==0){
                   6314:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6315:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6316:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6317:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6318:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6319:                 c12=cv12/sqrt(v1*v2);
                   6320:                 /* Computing eigen value of matrix of covariance */
                   6321:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6322:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6323:                 if ((lc2 <0) || (lc1 <0) ){
                   6324:                   if(first2==1){
                   6325:                     first1=0;
                   6326:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6327:                   }
                   6328:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6329:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6330:                   /* lc2=fabs(lc2); */
                   6331:                 }
1.220     brouard  6332:                                                                
1.222     brouard  6333:                 /* Eigen vectors */
                   6334:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6335:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6336:                 v21=(lc1-v1)/cv12*v11;
                   6337:                 v12=-v21;
                   6338:                 v22=v11;
                   6339:                 tnalp=v21/v11;
                   6340:                 if(first1==1){
                   6341:                   first1=0;
                   6342:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6343:                 }
                   6344:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6345:                 /*printf(fignu*/
                   6346:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6347:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6348:                 if(first==1){
                   6349:                   first=0;
                   6350:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6351:                   fprintf(ficgp,"\nset parametric;unset label");
                   6352:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6353:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6354:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6355:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6356: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6357:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6358:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6359:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6360:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6361:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6362:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6363:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6364:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6365:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6366:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6367:                 }else{
                   6368:                   first=0;
                   6369:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6370:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6371:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6372:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6373:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6374:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6375:                 }/* if first */
                   6376:               } /* age mod 5 */
                   6377:             } /* end loop age */
                   6378:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6379:             first=1;
                   6380:           } /*l12 */
                   6381:         } /* k12 */
                   6382:        } /*l1 */
                   6383:      }/* k1 */
                   6384:    }  /* loop on combination of covariates j1 */
                   6385:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6386:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6387:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6388:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6389:    free_vector(xp,1,npar);
                   6390:    fclose(ficresprob);
                   6391:    fclose(ficresprobcov);
                   6392:    fclose(ficresprobcor);
                   6393:    fflush(ficgp);
                   6394:    fflush(fichtmcov);
                   6395:  }
1.126     brouard  6396: 
                   6397: 
                   6398: /******************* Printing html file ***********/
1.201     brouard  6399: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6400:                  int lastpass, int stepm, int weightopt, char model[],\
                   6401:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6402:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6403:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6404:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6405:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6406: 
                   6407:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6408:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6409: </ul>");
1.237     brouard  6410:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6411: </ul>", model);
1.214     brouard  6412:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6413:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6414:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6415:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6416:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6417:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6418:    fprintf(fichtm,"\
                   6419:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6420:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6421:    fprintf(fichtm,"\
1.217     brouard  6422:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6423:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6424:    fprintf(fichtm,"\
1.126     brouard  6425:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6426:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6427:    fprintf(fichtm,"\
1.217     brouard  6428:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6429:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6430:    fprintf(fichtm,"\
1.211     brouard  6431:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6432:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6433:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6434:    if(prevfcast==1){
                   6435:      fprintf(fichtm,"\
                   6436:  - Prevalence projections by age and states:                           \
1.201     brouard  6437:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6438:    }
1.126     brouard  6439: 
                   6440: 
1.225     brouard  6441:    m=pow(2,cptcoveff);
1.222     brouard  6442:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6443: 
1.264   ! brouard  6444:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
        !          6445: 
        !          6446:    jj1=0;
        !          6447: 
        !          6448:    fprintf(fichtm," \n<ul>");
        !          6449:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          6450:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
        !          6451:      if(m != 1 && TKresult[nres]!= k1)
        !          6452:        continue;
        !          6453:      jj1++;
        !          6454:      if (cptcovn > 0) {
        !          6455:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
        !          6456:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
        !          6457:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
        !          6458:        }
        !          6459:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6460:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6461:        }
        !          6462:        fprintf(fichtm,"\">");
        !          6463:        
        !          6464:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
        !          6465:        fprintf(fichtm,"************ Results for covariates");
        !          6466:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
        !          6467:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
        !          6468:        }
        !          6469:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6470:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6471:        }
        !          6472:        if(invalidvarcomb[k1]){
        !          6473:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
        !          6474:         continue;
        !          6475:        }
        !          6476:        fprintf(fichtm,"</a></li>");
        !          6477:      } /* cptcovn >0 */
        !          6478:    }
        !          6479:      fprintf(fichtm," \n</ul>");
        !          6480: 
1.222     brouard  6481:    jj1=0;
1.237     brouard  6482: 
                   6483:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6484:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6485:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6486:        continue;
1.220     brouard  6487: 
1.222     brouard  6488:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6489:      jj1++;
                   6490:      if (cptcovn > 0) {
1.264   ! brouard  6491:        fprintf(fichtm,"\n<p><a name=\"rescov");
        !          6492:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
        !          6493:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
        !          6494:        }
        !          6495:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6496:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6497:        }
        !          6498:        fprintf(fichtm,"\"</a>");
        !          6499:  
1.222     brouard  6500:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6501:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6502:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6503:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6504:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6505:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6506:        }
1.237     brouard  6507:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6508:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6509:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6510:       }
                   6511:        
1.230     brouard  6512:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6513:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6514:        if(invalidvarcomb[k1]){
                   6515:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6516:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6517:         continue;
                   6518:        }
                   6519:      }
                   6520:      /* aij, bij */
1.259     brouard  6521:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6522: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6523:      /* Pij */
1.241     brouard  6524:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6525: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6526:      /* Quasi-incidences */
                   6527:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6528:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6529:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6530: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6531: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6532:      /* Survival functions (period) in state j */
                   6533:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6534:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6535: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6536:      }
                   6537:      /* State specific survival functions (period) */
                   6538:      for(cpt=1; cpt<=nlstate;cpt++){
                   6539:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6540:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6541:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6542:      }
                   6543:      /* Period (stable) prevalence in each health state */
                   6544:      for(cpt=1; cpt<=nlstate;cpt++){
1.264   ! brouard  6545:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
        !          6546: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6547:      }
                   6548:      if(backcast==1){
                   6549:        /* Period (stable) back prevalence in each health state */
                   6550:        for(cpt=1; cpt<=nlstate;cpt++){
1.264   ! brouard  6551:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6552: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6553:        }
1.217     brouard  6554:      }
1.222     brouard  6555:      if(prevfcast==1){
                   6556:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6557:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6558:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6559: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6560:        }
                   6561:      }
1.220     brouard  6562:         
1.222     brouard  6563:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6564:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6565: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6566:      }
                   6567:      /* } /\* end i1 *\/ */
                   6568:    }/* End k1 */
                   6569:    fprintf(fichtm,"</ul>");
1.126     brouard  6570: 
1.222     brouard  6571:    fprintf(fichtm,"\
1.126     brouard  6572: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6573:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6574:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6575: But because parameters are usually highly correlated (a higher incidence of disability \
                   6576: and a higher incidence of recovery can give very close observed transition) it might \
                   6577: be very useful to look not only at linear confidence intervals estimated from the \
                   6578: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6579: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6580: covariance matrix of the one-step probabilities. \
                   6581: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6582: 
1.222     brouard  6583:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6584:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6585:    fprintf(fichtm,"\
1.126     brouard  6586:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6587:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6588: 
1.222     brouard  6589:    fprintf(fichtm,"\
1.126     brouard  6590:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6591:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6592:    fprintf(fichtm,"\
1.126     brouard  6593:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6594:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6595:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6596:    fprintf(fichtm,"\
1.126     brouard  6597:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6598:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6599:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6600:    fprintf(fichtm,"\
1.128     brouard  6601:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6602:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6603:    fprintf(fichtm,"\
1.128     brouard  6604:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6605:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6606:    fprintf(fichtm,"\
1.126     brouard  6607:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6608:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6609: 
                   6610: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6611: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6612: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6613: /*     <br>",fileres,fileres,fileres,fileres); */
                   6614: /*  else  */
                   6615: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6616:    fflush(fichtm);
                   6617:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6618: 
1.225     brouard  6619:    m=pow(2,cptcoveff);
1.222     brouard  6620:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6621: 
1.222     brouard  6622:    jj1=0;
1.237     brouard  6623: 
1.241     brouard  6624:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6625:    for(k1=1; k1<=m;k1++){
1.253     brouard  6626:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6627:        continue;
1.222     brouard  6628:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6629:      jj1++;
1.126     brouard  6630:      if (cptcovn > 0) {
                   6631:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6632:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6633:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6634:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6635:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6636:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6637:       }
                   6638: 
1.126     brouard  6639:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6640: 
1.222     brouard  6641:        if(invalidvarcomb[k1]){
                   6642:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6643:         continue;
                   6644:        }
1.126     brouard  6645:      }
                   6646:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6647:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6648: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6649: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6650:      }
                   6651:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6652: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6653: true period expectancies (those weighted with period prevalences are also\
                   6654:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6655:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6656: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6657:      /* } /\* end i1 *\/ */
                   6658:    }/* End k1 */
1.241     brouard  6659:   }/* End nres */
1.222     brouard  6660:    fprintf(fichtm,"</ul>");
                   6661:    fflush(fichtm);
1.126     brouard  6662: }
                   6663: 
                   6664: /******************* Gnuplot file **************/
1.223     brouard  6665: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6666: 
                   6667:   char dirfileres[132],optfileres[132];
1.264   ! brouard  6668:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6669:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6670:   int lv=0, vlv=0, kl=0;
1.130     brouard  6671:   int ng=0;
1.201     brouard  6672:   int vpopbased;
1.223     brouard  6673:   int ioffset; /* variable offset for columns */
1.235     brouard  6674:   int nres=0; /* Index of resultline */
1.219     brouard  6675: 
1.126     brouard  6676: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6677: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6678: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6679: /*   } */
                   6680: 
                   6681:   /*#ifdef windows */
                   6682:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6683:   /*#endif */
1.225     brouard  6684:   m=pow(2,cptcoveff);
1.126     brouard  6685: 
1.202     brouard  6686:   /* Contribution to likelihood */
                   6687:   /* Plot the probability implied in the likelihood */
1.223     brouard  6688:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6689:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6690:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6691:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6692: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6693:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6694: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6695:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6696:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6697:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6698:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6699:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6700:   for (i=1; i<= nlstate ; i ++) {
                   6701:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6702:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6703:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6704:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6705:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6706:     }
                   6707:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6708:   }
                   6709:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6710:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6711:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6712:   fprintf(ficgp,"\nset out;unset log\n");
                   6713:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6714: 
1.126     brouard  6715:   strcpy(dirfileres,optionfilefiname);
                   6716:   strcpy(optfileres,"vpl");
1.223     brouard  6717:   /* 1eme*/
1.238     brouard  6718:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6719:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6720:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6721:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6722:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6723:          continue;
                   6724:        /* We are interested in selected combination by the resultline */
1.246     brouard  6725:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6726:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264   ! brouard  6727:        strcpy(gplotlabel,"(");
1.238     brouard  6728:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6729:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6730:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6731:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6732:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6733:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6734:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6735:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6736:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  6737:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6738:        }
                   6739:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6740:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6741:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  6742:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6743:        }
        !          6744:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  6745:        /* printf("\n#\n"); */
1.238     brouard  6746:        fprintf(ficgp,"\n#\n");
                   6747:        if(invalidvarcomb[k1]){
1.260     brouard  6748:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  6749:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6750:          continue;
                   6751:        }
1.235     brouard  6752:       
1.241     brouard  6753:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6754:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264   ! brouard  6755:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  6756:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   6757:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   6758:       /* k1-1 error should be nres-1*/
1.238     brouard  6759:        for (i=1; i<= nlstate ; i ++) {
                   6760:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6761:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6762:        }
1.260     brouard  6763:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  6764:        for (i=1; i<= nlstate ; i ++) {
                   6765:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6766:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6767:        } 
1.260     brouard  6768:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  6769:        for (i=1; i<= nlstate ; i ++) {
                   6770:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6771:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6772:        }  
                   6773:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6774:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6775:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6776:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6777:          if(cptcoveff ==0){
1.245     brouard  6778:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6779:          }else{
                   6780:            kl=0;
                   6781:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6782:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6783:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6784:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6785:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6786:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6787:              kl++;
1.238     brouard  6788:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6789:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6790:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6791:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6792:              if(k==cptcoveff){
1.245     brouard  6793:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6794:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6795:              }else{
                   6796:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6797:                kl++;
                   6798:              }
                   6799:            } /* end covariate */
                   6800:          } /* end if no covariate */
                   6801:        } /* end if backcast */
1.264   ! brouard  6802:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  6803:       } /* nres */
1.201     brouard  6804:     } /* k1 */
                   6805:   } /* cpt */
1.235     brouard  6806: 
                   6807:   
1.126     brouard  6808:   /*2 eme*/
1.238     brouard  6809:   for (k1=1; k1<= m ; k1 ++){  
                   6810:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6811:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6812:        continue;
                   6813:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264   ! brouard  6814:       strcpy(gplotlabel,"(");
1.238     brouard  6815:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6816:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6817:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6818:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6819:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6820:        vlv= nbcode[Tvaraff[k]][lv];
                   6821:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  6822:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6823:       }
1.237     brouard  6824:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6825:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6826:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6827:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  6828:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6829:       }
1.264   ! brouard  6830:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  6831:       fprintf(ficgp,"\n#\n");
1.223     brouard  6832:       if(invalidvarcomb[k1]){
                   6833:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6834:        continue;
                   6835:       }
1.219     brouard  6836:                        
1.241     brouard  6837:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6838:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264   ! brouard  6839:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
        !          6840:        if(vpopbased==0){
1.238     brouard  6841:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264   ! brouard  6842:        }else
1.238     brouard  6843:          fprintf(ficgp,"\nreplot ");
                   6844:        for (i=1; i<= nlstate+1 ; i ++) {
                   6845:          k=2*i;
1.261     brouard  6846:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  6847:          for (j=1; j<= nlstate+1 ; j ++) {
                   6848:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6849:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6850:          }   
                   6851:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6852:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  6853:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6854:          for (j=1; j<= nlstate+1 ; j ++) {
                   6855:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6856:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6857:          }   
                   6858:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  6859:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6860:          for (j=1; j<= nlstate+1 ; j ++) {
                   6861:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6862:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6863:          }   
                   6864:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6865:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6866:        } /* state */
                   6867:       } /* vpopbased */
1.264   ! brouard  6868:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6869:     } /* end nres */
                   6870:   } /* k1 end 2 eme*/
                   6871:        
                   6872:        
                   6873:   /*3eme*/
                   6874:   for (k1=1; k1<= m ; k1 ++){
                   6875:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6876:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6877:        continue;
                   6878: 
                   6879:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  6880:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264   ! brouard  6881:        strcpy(gplotlabel,"(");
1.238     brouard  6882:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6883:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6884:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6885:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6886:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6887:          vlv= nbcode[Tvaraff[k]][lv];
                   6888:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  6889:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6890:        }
                   6891:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6892:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  6893:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6894:        }       
1.264   ! brouard  6895:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  6896:        fprintf(ficgp,"\n#\n");
                   6897:        if(invalidvarcomb[k1]){
                   6898:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6899:          continue;
                   6900:        }
                   6901:                        
                   6902:        /*       k=2+nlstate*(2*cpt-2); */
                   6903:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6904:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264   ! brouard  6905:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  6906:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  6907: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  6908:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6909:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6910:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6911:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6912:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6913:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6914:                                
1.238     brouard  6915:        */
                   6916:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  6917:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  6918:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6919:                                
1.238     brouard  6920:        } 
1.261     brouard  6921:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  6922:       }
1.264   ! brouard  6923:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  6924:     } /* end nres */
                   6925:   } /* end kl 3eme */
1.126     brouard  6926:   
1.223     brouard  6927:   /* 4eme */
1.201     brouard  6928:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6929:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6930:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6931:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6932:        continue;
1.238     brouard  6933:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264   ! brouard  6934:        strcpy(gplotlabel,"(");
1.238     brouard  6935:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6936:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6937:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6938:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6939:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6940:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6941:          vlv= nbcode[Tvaraff[k]][lv];
                   6942:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  6943:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6944:        }
                   6945:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6946:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  6947:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6948:        }       
1.264   ! brouard  6949:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  6950:        fprintf(ficgp,"\n#\n");
                   6951:        if(invalidvarcomb[k1]){
                   6952:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6953:          continue;
1.223     brouard  6954:        }
1.238     brouard  6955:       
1.241     brouard  6956:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264   ! brouard  6957:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  6958:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6959: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6960:        k=3;
                   6961:        for (i=1; i<= nlstate ; i ++){
                   6962:          if(i==1){
                   6963:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6964:          }else{
                   6965:            fprintf(ficgp,", '' ");
                   6966:          }
                   6967:          l=(nlstate+ndeath)*(i-1)+1;
                   6968:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6969:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6970:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6971:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6972:        } /* nlstate */
1.264   ! brouard  6973:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  6974:       } /* end cpt state*/ 
                   6975:     } /* end nres */
                   6976:   } /* end covariate k1 */  
                   6977: 
1.220     brouard  6978: /* 5eme */
1.201     brouard  6979:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6980:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6981:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6982:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6983:        continue;
1.238     brouard  6984:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264   ! brouard  6985:        strcpy(gplotlabel,"(");
1.238     brouard  6986:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6987:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6988:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6989:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6990:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6991:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6992:          vlv= nbcode[Tvaraff[k]][lv];
                   6993:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  6994:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6995:        }
                   6996:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6997:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  6998:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6999:        }       
1.264   ! brouard  7000:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7001:        fprintf(ficgp,"\n#\n");
                   7002:        if(invalidvarcomb[k1]){
                   7003:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7004:          continue;
                   7005:        }
1.227     brouard  7006:       
1.241     brouard  7007:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264   ! brouard  7008:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7009:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7010: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7011:        k=3;
                   7012:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7013:          if(j==1)
                   7014:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7015:          else
                   7016:            fprintf(ficgp,", '' ");
                   7017:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7018:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7019:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7020:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7021:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7022:        } /* nlstate */
                   7023:        fprintf(ficgp,", '' ");
                   7024:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7025:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7026:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7027:          if(j < nlstate)
                   7028:            fprintf(ficgp,"$%d +",k+l);
                   7029:          else
                   7030:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7031:        }
1.264   ! brouard  7032:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7033:       } /* end cpt state*/ 
                   7034:     } /* end covariate */  
                   7035:   } /* end nres */
1.227     brouard  7036:   
1.220     brouard  7037: /* 6eme */
1.202     brouard  7038:   /* CV preval stable (period) for each covariate */
1.237     brouard  7039:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7040:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7041:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7042:       continue;
1.255     brouard  7043:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264   ! brouard  7044:       strcpy(gplotlabel,"(");      
1.211     brouard  7045:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7046:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7047:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7048:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7049:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7050:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7051:        vlv= nbcode[Tvaraff[k]][lv];
                   7052:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  7053:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7054:       }
1.237     brouard  7055:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7056:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  7057:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7058:       }        
1.264   ! brouard  7059:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7060:       fprintf(ficgp,"\n#\n");
1.223     brouard  7061:       if(invalidvarcomb[k1]){
1.227     brouard  7062:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7063:        continue;
1.223     brouard  7064:       }
1.227     brouard  7065:       
1.241     brouard  7066:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264   ! brouard  7067:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7068:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7069: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7070:       k=3; /* Offset */
1.255     brouard  7071:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7072:        if(i==1)
                   7073:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7074:        else
                   7075:          fprintf(ficgp,", '' ");
1.255     brouard  7076:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7077:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7078:        for (j=2; j<= nlstate ; j ++)
                   7079:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7080:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7081:       } /* nlstate */
1.264   ! brouard  7082:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7083:     } /* end cpt state*/ 
                   7084:   } /* end covariate */  
1.227     brouard  7085:   
                   7086:   
1.220     brouard  7087: /* 7eme */
1.218     brouard  7088:   if(backcast == 1){
1.217     brouard  7089:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7090:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7091:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7092:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7093:        continue;
1.255     brouard  7094:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
1.264   ! brouard  7095:        strcpy(gplotlabel,"(");      
        !          7096:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7097:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7098:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7099:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7100:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7101:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7102:          vlv= nbcode[Tvaraff[k]][lv];
                   7103:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  7104:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7105:        }
1.237     brouard  7106:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7107:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  7108:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7109:        }       
1.264   ! brouard  7110:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7111:        fprintf(ficgp,"\n#\n");
                   7112:        if(invalidvarcomb[k1]){
                   7113:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7114:          continue;
                   7115:        }
                   7116:        
1.241     brouard  7117:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.264   ! brouard  7118:        fprintf(ficgp,"set label \"Ending alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7119:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7120: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7121:        k=3; /* Offset */
1.255     brouard  7122:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7123:          if(i==1)
                   7124:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7125:          else
                   7126:            fprintf(ficgp,", '' ");
                   7127:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7128:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7129:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7130:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7131:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7132:          /* for (j=2; j<= nlstate ; j ++) */
                   7133:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7134:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7135:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7136:        } /* nlstate */
1.264   ! brouard  7137:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7138:       } /* end cpt state*/ 
                   7139:     } /* end covariate */  
                   7140:   } /* End if backcast */
                   7141:   
1.223     brouard  7142:   /* 8eme */
1.218     brouard  7143:   if(prevfcast==1){
                   7144:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7145:     
1.237     brouard  7146:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7147:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7148:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7149:        continue;
1.211     brouard  7150:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264   ! brouard  7151:        strcpy(gplotlabel,"(");      
1.227     brouard  7152:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7153:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7154:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7155:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7156:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7157:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7158:          vlv= nbcode[Tvaraff[k]][lv];
                   7159:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264   ! brouard  7160:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7161:        }
1.237     brouard  7162:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7163:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  7164:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7165:        }       
1.264   ! brouard  7166:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7167:        fprintf(ficgp,"\n#\n");
                   7168:        if(invalidvarcomb[k1]){
                   7169:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7170:          continue;
                   7171:        }
                   7172:        
                   7173:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7174:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264   ! brouard  7175:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7176:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7177: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7178:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7179:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7180:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7181:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7182:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7183:          if(i==1){
                   7184:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7185:          }else{
                   7186:            fprintf(ficgp,",\\\n '' ");
                   7187:          }
                   7188:          if(cptcoveff ==0){ /* No covariate */
                   7189:            ioffset=2; /* Age is in 2 */
                   7190:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7191:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7192:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7193:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7194:            fprintf(ficgp," u %d:(", ioffset); 
                   7195:            if(i==nlstate+1)
                   7196:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7197:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7198:            else
                   7199:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7200:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7201:          }else{ /* more than 2 covariates */
                   7202:            if(cptcoveff ==1){
                   7203:              ioffset=4; /* Age is in 4 */
                   7204:            }else{
                   7205:              ioffset=6; /* Age is in 6 */
                   7206:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7207:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7208:            }   
                   7209:            fprintf(ficgp," u %d:(",ioffset); 
                   7210:            kl=0;
                   7211:            strcpy(gplotcondition,"(");
                   7212:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7213:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7214:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7215:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7216:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7217:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7218:              kl++;
                   7219:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7220:              kl++;
                   7221:              if(k <cptcoveff && cptcoveff>1)
                   7222:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7223:            }
                   7224:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7225:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7226:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7227:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7228:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7229:            if(i==nlstate+1){
                   7230:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7231:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7232:            }else{
                   7233:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7234:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7235:            }
                   7236:          } /* end if covariate */
                   7237:        } /* nlstate */
1.264   ! brouard  7238:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7239:       } /* end cpt state*/
                   7240:     } /* end covariate */
                   7241:   } /* End if prevfcast */
1.227     brouard  7242:   
                   7243:   
1.238     brouard  7244:   /* 9eme writing MLE parameters */
                   7245:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7246:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7247:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7248:     for(k=1; k <=(nlstate+ndeath); k++){
                   7249:       if (k != i) {
1.227     brouard  7250:        fprintf(ficgp,"#   current state %d\n",k);
                   7251:        for(j=1; j <=ncovmodel; j++){
                   7252:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7253:          jk++; 
                   7254:        }
                   7255:        fprintf(ficgp,"\n");
1.126     brouard  7256:       }
                   7257:     }
1.223     brouard  7258:   }
1.187     brouard  7259:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7260:   
1.145     brouard  7261:   /*goto avoid;*/
1.238     brouard  7262:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7263:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7264:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7265:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7266:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7267:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7268:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7269:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7270:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7271:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7272:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7273:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7274:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7275:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7276:   fprintf(ficgp,"#\n");
1.223     brouard  7277:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7278:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7279:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7280:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264   ! brouard  7281:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
        !          7282:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7283:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264   ! brouard  7284:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7285:        continue;
1.264   ! brouard  7286:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
        !          7287:       strcpy(gplotlabel,"(");
        !          7288:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
        !          7289:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
        !          7290:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
        !          7291:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
        !          7292:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
        !          7293:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
        !          7294:        vlv= nbcode[Tvaraff[k]][lv];
        !          7295:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
        !          7296:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
        !          7297:       }
1.237     brouard  7298:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7299:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264   ! brouard  7300:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7301:       }        
1.264   ! brouard  7302:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7303:       fprintf(ficgp,"\n#\n");
1.264   ! brouard  7304:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
        !          7305:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7306:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7307:       if (ng==1){
                   7308:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7309:        fprintf(ficgp,"\nunset log y");
                   7310:       }else if (ng==2){
                   7311:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7312:        fprintf(ficgp,"\nset log y");
                   7313:       }else if (ng==3){
                   7314:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7315:        fprintf(ficgp,"\nset log y");
                   7316:       }else
                   7317:        fprintf(ficgp,"\nunset title ");
                   7318:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7319:       i=1;
                   7320:       for(k2=1; k2<=nlstate; k2++) {
                   7321:        k3=i;
                   7322:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7323:          if (k != k2){
                   7324:            switch( ng) {
                   7325:            case 1:
                   7326:              if(nagesqr==0)
                   7327:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7328:              else /* nagesqr =1 */
                   7329:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7330:              break;
                   7331:            case 2: /* ng=2 */
                   7332:              if(nagesqr==0)
                   7333:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7334:              else /* nagesqr =1 */
                   7335:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7336:              break;
                   7337:            case 3:
                   7338:              if(nagesqr==0)
                   7339:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7340:              else /* nagesqr =1 */
                   7341:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7342:              break;
                   7343:            }
                   7344:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7345:            ijp=1; /* product no age */
                   7346:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7347:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7348:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7349:              if(j==Tage[ij]) { /* Product by age */
                   7350:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7351:                  if(DummyV[j]==0){
1.237     brouard  7352:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7353:                  }else{ /* quantitative */
                   7354:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
1.264   ! brouard  7355:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.237     brouard  7356:                  }
                   7357:                  ij++;
                   7358:                }
                   7359:              }else if(j==Tprod[ijp]) { /* */ 
                   7360:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7361:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7362:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7363:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.264   ! brouard  7364:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
1.237     brouard  7365:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7366:                    }else{ /* Vn is dummy and Vm is quanti */
1.264   ! brouard  7367:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
1.237     brouard  7368:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7369:                    }
                   7370:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7371:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7372:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7373:                    }else{ /* Both quanti */
                   7374:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7375:                    }
                   7376:                  }
1.238     brouard  7377:                  ijp++;
1.237     brouard  7378:                }
                   7379:              } else{  /* simple covariate */
1.264   ! brouard  7380:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7381:                if(Dummy[j]==0){
                   7382:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7383:                }else{ /* quantitative */
                   7384:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264   ! brouard  7385:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7386:                }
1.237     brouard  7387:              } /* end simple */
                   7388:            } /* end j */
1.223     brouard  7389:          }else{
                   7390:            i=i-ncovmodel;
                   7391:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7392:              fprintf(ficgp," (1.");
                   7393:          }
1.227     brouard  7394:          
1.223     brouard  7395:          if(ng != 1){
                   7396:            fprintf(ficgp,")/(1");
1.227     brouard  7397:            
1.264   ! brouard  7398:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7399:              if(nagesqr==0)
1.264   ! brouard  7400:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7401:              else /* nagesqr =1 */
1.264   ! brouard  7402:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7403:               
1.223     brouard  7404:              ij=1;
                   7405:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7406:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7407:                  if(ij <=cptcovage) { /* Bug valgrind */
1.264   ! brouard  7408:                    fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
        !          7409:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7410:                    ij++;
                   7411:                  }
                   7412:                }
                   7413:                else
1.264   ! brouard  7414:                  fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7415:              }
                   7416:              fprintf(ficgp,")");
                   7417:            }
                   7418:            fprintf(ficgp,")");
                   7419:            if(ng ==2)
                   7420:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7421:            else /* ng= 3 */
                   7422:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7423:          }else{ /* end ng <> 1 */
                   7424:            if( k !=k2) /* logit p11 is hard to draw */
                   7425:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7426:          }
                   7427:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7428:            fprintf(ficgp,",");
                   7429:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7430:            fprintf(ficgp,",");
                   7431:          i=i+ncovmodel;
                   7432:        } /* end k */
                   7433:       } /* end k2 */
1.264   ! brouard  7434:       fprintf(ficgp,"\n set out; unset label;\n");
        !          7435:     } /* end k1 */
1.223     brouard  7436:   } /* end ng */
                   7437:   /* avoid: */
                   7438:   fflush(ficgp); 
1.126     brouard  7439: }  /* end gnuplot */
                   7440: 
                   7441: 
                   7442: /*************** Moving average **************/
1.219     brouard  7443: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7444:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7445:    
1.222     brouard  7446:    int i, cpt, cptcod;
                   7447:    int modcovmax =1;
                   7448:    int mobilavrange, mob;
                   7449:    int iage=0;
                   7450: 
                   7451:    double sum=0.;
                   7452:    double age;
                   7453:    double *sumnewp, *sumnewm;
                   7454:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7455:   
                   7456:   
1.225     brouard  7457:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7458:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7459: 
                   7460:    sumnewp = vector(1,ncovcombmax);
                   7461:    sumnewm = vector(1,ncovcombmax);
                   7462:    agemingood = vector(1,ncovcombmax); 
                   7463:    agemaxgood = vector(1,ncovcombmax);
                   7464: 
                   7465:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7466:      sumnewm[cptcod]=0.;
                   7467:      sumnewp[cptcod]=0.;
                   7468:      agemingood[cptcod]=0;
                   7469:      agemaxgood[cptcod]=0;
                   7470:    }
                   7471:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7472:   
                   7473:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7474:      if(mobilav==1) mobilavrange=5; /* default */
                   7475:      else mobilavrange=mobilav;
                   7476:      for (age=bage; age<=fage; age++)
                   7477:        for (i=1; i<=nlstate;i++)
                   7478:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7479:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7480:      /* We keep the original values on the extreme ages bage, fage and for 
                   7481:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7482:        we use a 5 terms etc. until the borders are no more concerned. 
                   7483:      */ 
                   7484:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7485:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7486:         for (i=1; i<=nlstate;i++){
                   7487:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7488:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7489:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7490:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7491:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7492:             }
                   7493:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7494:           }
                   7495:         }
                   7496:        }/* end age */
                   7497:      }/* end mob */
                   7498:    }else
                   7499:      return -1;
                   7500:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7501:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7502:      if(invalidvarcomb[cptcod]){
                   7503:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7504:        continue;
                   7505:      }
1.219     brouard  7506: 
1.222     brouard  7507:      agemingood[cptcod]=fage-(mob-1)/2;
                   7508:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7509:        sumnewm[cptcod]=0.;
                   7510:        for (i=1; i<=nlstate;i++){
                   7511:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7512:        }
                   7513:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7514:         agemingood[cptcod]=age;
                   7515:        }else{ /* bad */
                   7516:         for (i=1; i<=nlstate;i++){
                   7517:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7518:         } /* i */
                   7519:        } /* end bad */
                   7520:      }/* age */
                   7521:      sum=0.;
                   7522:      for (i=1; i<=nlstate;i++){
                   7523:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7524:      }
                   7525:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7526:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7527:        /* for (i=1; i<=nlstate;i++){ */
                   7528:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7529:        /* } /\* i *\/ */
                   7530:      } /* end bad */
                   7531:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7532:      /* From youngest, finding the oldest wrong */
                   7533:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7534:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7535:        sumnewm[cptcod]=0.;
                   7536:        for (i=1; i<=nlstate;i++){
                   7537:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7538:        }
                   7539:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7540:         agemaxgood[cptcod]=age;
                   7541:        }else{ /* bad */
                   7542:         for (i=1; i<=nlstate;i++){
                   7543:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7544:         } /* i */
                   7545:        } /* end bad */
                   7546:      }/* age */
                   7547:      sum=0.;
                   7548:      for (i=1; i<=nlstate;i++){
                   7549:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7550:      }
                   7551:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7552:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7553:        /* for (i=1; i<=nlstate;i++){ */
                   7554:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7555:        /* } /\* i *\/ */
                   7556:      } /* end bad */
                   7557:                
                   7558:      for (age=bage; age<=fage; age++){
1.235     brouard  7559:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7560:        sumnewp[cptcod]=0.;
                   7561:        sumnewm[cptcod]=0.;
                   7562:        for (i=1; i<=nlstate;i++){
                   7563:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7564:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7565:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7566:        }
                   7567:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7568:      }
                   7569:      /* printf("\n"); */
                   7570:      /* } */
                   7571:      /* brutal averaging */
                   7572:      for (i=1; i<=nlstate;i++){
                   7573:        for (age=1; age<=bage; age++){
                   7574:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7575:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7576:        }       
                   7577:        for (age=fage; age<=AGESUP; age++){
                   7578:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7579:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7580:        }
                   7581:      } /* end i status */
                   7582:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7583:        for (age=1; age<=AGESUP; age++){
                   7584:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7585:         mobaverage[(int)age][i][cptcod]=0.;
                   7586:        }
                   7587:      }
                   7588:    }/* end cptcod */
                   7589:    free_vector(sumnewm,1, ncovcombmax);
                   7590:    free_vector(sumnewp,1, ncovcombmax);
                   7591:    free_vector(agemaxgood,1, ncovcombmax);
                   7592:    free_vector(agemingood,1, ncovcombmax);
                   7593:    return 0;
                   7594:  }/* End movingaverage */
1.218     brouard  7595:  
1.126     brouard  7596: 
                   7597: /************** Forecasting ******************/
1.235     brouard  7598:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7599:   /* proj1, year, month, day of starting projection 
                   7600:      agemin, agemax range of age
                   7601:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7602:      anproj2 year of en of projection (same day and month as proj1).
                   7603:   */
1.235     brouard  7604:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7605:   double agec; /* generic age */
                   7606:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7607:   double *popeffectif,*popcount;
                   7608:   double ***p3mat;
1.218     brouard  7609:   /* double ***mobaverage; */
1.126     brouard  7610:   char fileresf[FILENAMELENGTH];
                   7611: 
                   7612:   agelim=AGESUP;
1.211     brouard  7613:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7614:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7615:      We still use firstpass and lastpass as another selection.
                   7616:   */
1.214     brouard  7617:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7618:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7619:  
1.201     brouard  7620:   strcpy(fileresf,"F_"); 
                   7621:   strcat(fileresf,fileresu);
1.126     brouard  7622:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7623:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7624:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7625:   }
1.235     brouard  7626:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7627:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7628: 
1.225     brouard  7629:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7630: 
                   7631: 
                   7632:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7633:   if (stepm<=12) stepsize=1;
                   7634:   if(estepm < stepm){
                   7635:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7636:   }
                   7637:   else  hstepm=estepm;   
                   7638: 
                   7639:   hstepm=hstepm/stepm; 
                   7640:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7641:                                fractional in yp1 */
                   7642:   anprojmean=yp;
                   7643:   yp2=modf((yp1*12),&yp);
                   7644:   mprojmean=yp;
                   7645:   yp1=modf((yp2*30.5),&yp);
                   7646:   jprojmean=yp;
                   7647:   if(jprojmean==0) jprojmean=1;
                   7648:   if(mprojmean==0) jprojmean=1;
                   7649: 
1.227     brouard  7650:   i1=pow(2,cptcoveff);
1.126     brouard  7651:   if (cptcovn < 1){i1=1;}
                   7652:   
                   7653:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7654:   
                   7655:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7656:   
1.126     brouard  7657: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7658:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7659:   for(k=1; k<=i1;k++){
1.253     brouard  7660:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7661:       continue;
1.227     brouard  7662:     if(invalidvarcomb[k]){
                   7663:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7664:       continue;
                   7665:     }
                   7666:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7667:     for(j=1;j<=cptcoveff;j++) {
                   7668:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7669:     }
1.235     brouard  7670:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7671:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7672:     }
1.227     brouard  7673:     fprintf(ficresf," yearproj age");
                   7674:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7675:       for(i=1; i<=nlstate;i++)               
                   7676:        fprintf(ficresf," p%d%d",i,j);
                   7677:       fprintf(ficresf," wp.%d",j);
                   7678:     }
                   7679:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7680:       fprintf(ficresf,"\n");
                   7681:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7682:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7683:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7684:        nhstepm = nhstepm/hstepm; 
                   7685:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7686:        oldm=oldms;savm=savms;
1.235     brouard  7687:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7688:        
                   7689:        for (h=0; h<=nhstepm; h++){
                   7690:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7691:            fprintf(ficresf,"\n");
                   7692:            for(j=1;j<=cptcoveff;j++) 
                   7693:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7694:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7695:          } 
                   7696:          for(j=1; j<=nlstate+ndeath;j++) {
                   7697:            ppij=0.;
                   7698:            for(i=1; i<=nlstate;i++) {
                   7699:              if (mobilav==1) 
                   7700:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7701:              else {
                   7702:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7703:              }
                   7704:              if (h*hstepm/YEARM*stepm== yearp) {
                   7705:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7706:              }
                   7707:            } /* end i */
                   7708:            if (h*hstepm/YEARM*stepm==yearp) {
                   7709:              fprintf(ficresf," %.3f", ppij);
                   7710:            }
                   7711:          }/* end j */
                   7712:        } /* end h */
                   7713:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7714:       } /* end agec */
                   7715:     } /* end yearp */
                   7716:   } /* end  k */
1.219     brouard  7717:        
1.126     brouard  7718:   fclose(ficresf);
1.215     brouard  7719:   printf("End of Computing forecasting \n");
                   7720:   fprintf(ficlog,"End of Computing forecasting\n");
                   7721: 
1.126     brouard  7722: }
                   7723: 
1.218     brouard  7724: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7725: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7726: /*   /\* back1, year, month, day of starting backection  */
                   7727: /*      agemin, agemax range of age */
                   7728: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7729: /*      anback2 year of en of backection (same day and month as back1). */
                   7730: /*   *\/ */
                   7731: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7732: /*   double agec; /\* generic age *\/ */
                   7733: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7734: /*   double *popeffectif,*popcount; */
                   7735: /*   double ***p3mat; */
                   7736: /*   /\* double ***mobaverage; *\/ */
                   7737: /*   char fileresfb[FILENAMELENGTH]; */
                   7738:        
                   7739: /*   agelim=AGESUP; */
                   7740: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7741: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7742: /*      We still use firstpass and lastpass as another selection. */
                   7743: /*   *\/ */
                   7744: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7745: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7746: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7747:        
                   7748: /*   strcpy(fileresfb,"FB_");  */
                   7749: /*   strcat(fileresfb,fileresu); */
                   7750: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7751: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7752: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7753: /*   } */
                   7754: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7755: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7756:        
1.225     brouard  7757: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7758:        
                   7759: /*   /\* if (mobilav!=0) { *\/ */
                   7760: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7761: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7762: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7763: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7764: /*   /\*   } *\/ */
                   7765: /*   /\* } *\/ */
                   7766:        
                   7767: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7768: /*   if (stepm<=12) stepsize=1; */
                   7769: /*   if(estepm < stepm){ */
                   7770: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7771: /*   } */
                   7772: /*   else  hstepm=estepm;    */
                   7773:        
                   7774: /*   hstepm=hstepm/stepm;  */
                   7775: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7776: /*                                fractional in yp1 *\/ */
                   7777: /*   anprojmean=yp; */
                   7778: /*   yp2=modf((yp1*12),&yp); */
                   7779: /*   mprojmean=yp; */
                   7780: /*   yp1=modf((yp2*30.5),&yp); */
                   7781: /*   jprojmean=yp; */
                   7782: /*   if(jprojmean==0) jprojmean=1; */
                   7783: /*   if(mprojmean==0) jprojmean=1; */
                   7784:        
1.225     brouard  7785: /*   i1=cptcoveff; */
1.218     brouard  7786: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7787:   
1.218     brouard  7788: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7789:   
1.218     brouard  7790: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7791:        
                   7792: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7793: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7794: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7795: /*       k=k+1; */
                   7796: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7797: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7798: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7799: /*       } */
                   7800: /*       fprintf(ficresfb," yearbproj age"); */
                   7801: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7802: /*                             for(i=1; i<=nlstate;i++)               */
                   7803: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7804: /*                             fprintf(ficresfb," p.%d",j); */
                   7805: /*       } */
                   7806: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7807: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7808: /*                             fprintf(ficresfb,"\n"); */
                   7809: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7810: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7811: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7812: /*                                     nhstepm = nhstepm/hstepm;  */
                   7813: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7814: /*                                     oldm=oldms;savm=savms; */
                   7815: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7816: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7817: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7818: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7819: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7820: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7821: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7822: /*                                             }  */
                   7823: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7824: /*                                                     ppij=0.; */
                   7825: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7826: /*                                                             if (mobilav==1)  */
                   7827: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7828: /*                                                             else { */
                   7829: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7830: /*                                                             } */
                   7831: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7832: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7833: /*                                                             } */
                   7834: /*                                                     } /\* end i *\/ */
                   7835: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7836: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7837: /*                                                     } */
                   7838: /*                                             }/\* end j *\/ */
                   7839: /*                                     } /\* end h *\/ */
                   7840: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7841: /*                             } /\* end agec *\/ */
                   7842: /*       } /\* end yearp *\/ */
                   7843: /*     } /\* end cptcod *\/ */
                   7844: /*   } /\* end  cptcov *\/ */
                   7845:        
                   7846: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7847:        
                   7848: /*   fclose(ficresfb); */
                   7849: /*   printf("End of Computing Back forecasting \n"); */
                   7850: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7851:        
1.218     brouard  7852: /* } */
1.217     brouard  7853: 
1.126     brouard  7854: /************** Forecasting *****not tested NB*************/
1.227     brouard  7855: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7856:   
1.227     brouard  7857: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7858: /*   int *popage; */
                   7859: /*   double calagedatem, agelim, kk1, kk2; */
                   7860: /*   double *popeffectif,*popcount; */
                   7861: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7862: /*   /\* double ***mobaverage; *\/ */
                   7863: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7864: 
1.227     brouard  7865: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7866: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7867: /*   agelim=AGESUP; */
                   7868: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7869:   
1.227     brouard  7870: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7871:   
                   7872:   
1.227     brouard  7873: /*   strcpy(filerespop,"POP_");  */
                   7874: /*   strcat(filerespop,fileresu); */
                   7875: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7876: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7877: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7878: /*   } */
                   7879: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7880: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7881: 
1.227     brouard  7882: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7883: 
1.227     brouard  7884: /*   /\* if (mobilav!=0) { *\/ */
                   7885: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7886: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7887: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7888: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7889: /*   /\*   } *\/ */
                   7890: /*   /\* } *\/ */
1.126     brouard  7891: 
1.227     brouard  7892: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7893: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7894:   
1.227     brouard  7895: /*   agelim=AGESUP; */
1.126     brouard  7896:   
1.227     brouard  7897: /*   hstepm=1; */
                   7898: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7899:        
1.227     brouard  7900: /*   if (popforecast==1) { */
                   7901: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7902: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7903: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7904: /*     }  */
                   7905: /*     popage=ivector(0,AGESUP); */
                   7906: /*     popeffectif=vector(0,AGESUP); */
                   7907: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7908:     
1.227     brouard  7909: /*     i=1;    */
                   7910: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7911:     
1.227     brouard  7912: /*     imx=i; */
                   7913: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7914: /*   } */
1.218     brouard  7915:   
1.227     brouard  7916: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7917: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7918: /*       k=k+1; */
                   7919: /*       fprintf(ficrespop,"\n#******"); */
                   7920: /*       for(j=1;j<=cptcoveff;j++) { */
                   7921: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7922: /*       } */
                   7923: /*       fprintf(ficrespop,"******\n"); */
                   7924: /*       fprintf(ficrespop,"# Age"); */
                   7925: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7926: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7927:       
1.227     brouard  7928: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7929: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7930:        
1.227     brouard  7931: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7932: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7933: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7934:          
1.227     brouard  7935: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7936: /*       oldm=oldms;savm=savms; */
                   7937: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7938:          
1.227     brouard  7939: /*       for (h=0; h<=nhstepm; h++){ */
                   7940: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7941: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7942: /*         }  */
                   7943: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7944: /*           kk1=0.;kk2=0; */
                   7945: /*           for(i=1; i<=nlstate;i++) {               */
                   7946: /*             if (mobilav==1)  */
                   7947: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7948: /*             else { */
                   7949: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7950: /*             } */
                   7951: /*           } */
                   7952: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7953: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7954: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7955: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7956: /*           } */
                   7957: /*         } */
                   7958: /*         for(i=1; i<=nlstate;i++){ */
                   7959: /*           kk1=0.; */
                   7960: /*           for(j=1; j<=nlstate;j++){ */
                   7961: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7962: /*           } */
                   7963: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7964: /*         } */
1.218     brouard  7965:            
1.227     brouard  7966: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7967: /*           for(j=1; j<=nlstate;j++)  */
                   7968: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7969: /*       } */
                   7970: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7971: /*     } */
                   7972: /*       } */
1.218     brouard  7973:       
1.227     brouard  7974: /*       /\******\/ */
1.218     brouard  7975:       
1.227     brouard  7976: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7977: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7978: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7979: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7980: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7981:          
1.227     brouard  7982: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7983: /*       oldm=oldms;savm=savms; */
                   7984: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7985: /*       for (h=0; h<=nhstepm; h++){ */
                   7986: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7987: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7988: /*         }  */
                   7989: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7990: /*           kk1=0.;kk2=0; */
                   7991: /*           for(i=1; i<=nlstate;i++) {               */
                   7992: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7993: /*           } */
                   7994: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7995: /*         } */
                   7996: /*       } */
                   7997: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7998: /*     } */
                   7999: /*       } */
                   8000: /*     }  */
                   8001: /*   } */
1.218     brouard  8002:   
1.227     brouard  8003: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8004:   
1.227     brouard  8005: /*   if (popforecast==1) { */
                   8006: /*     free_ivector(popage,0,AGESUP); */
                   8007: /*     free_vector(popeffectif,0,AGESUP); */
                   8008: /*     free_vector(popcount,0,AGESUP); */
                   8009: /*   } */
                   8010: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8011: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8012: /*   fclose(ficrespop); */
                   8013: /* } /\* End of popforecast *\/ */
1.218     brouard  8014:  
1.126     brouard  8015: int fileappend(FILE *fichier, char *optionfich)
                   8016: {
                   8017:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8018:     printf("Problem with file: %s\n", optionfich);
                   8019:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8020:     return (0);
                   8021:   }
                   8022:   fflush(fichier);
                   8023:   return (1);
                   8024: }
                   8025: 
                   8026: 
                   8027: /**************** function prwizard **********************/
                   8028: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8029: {
                   8030: 
                   8031:   /* Wizard to print covariance matrix template */
                   8032: 
1.164     brouard  8033:   char ca[32], cb[32];
                   8034:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8035:   int numlinepar;
                   8036: 
                   8037:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8038:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8039:   for(i=1; i <=nlstate; i++){
                   8040:     jj=0;
                   8041:     for(j=1; j <=nlstate+ndeath; j++){
                   8042:       if(j==i) continue;
                   8043:       jj++;
                   8044:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8045:       printf("%1d%1d",i,j);
                   8046:       fprintf(ficparo,"%1d%1d",i,j);
                   8047:       for(k=1; k<=ncovmodel;k++){
                   8048:        /*        printf(" %lf",param[i][j][k]); */
                   8049:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8050:        printf(" 0.");
                   8051:        fprintf(ficparo," 0.");
                   8052:       }
                   8053:       printf("\n");
                   8054:       fprintf(ficparo,"\n");
                   8055:     }
                   8056:   }
                   8057:   printf("# Scales (for hessian or gradient estimation)\n");
                   8058:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8059:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8060:   for(i=1; i <=nlstate; i++){
                   8061:     jj=0;
                   8062:     for(j=1; j <=nlstate+ndeath; j++){
                   8063:       if(j==i) continue;
                   8064:       jj++;
                   8065:       fprintf(ficparo,"%1d%1d",i,j);
                   8066:       printf("%1d%1d",i,j);
                   8067:       fflush(stdout);
                   8068:       for(k=1; k<=ncovmodel;k++){
                   8069:        /*      printf(" %le",delti3[i][j][k]); */
                   8070:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8071:        printf(" 0.");
                   8072:        fprintf(ficparo," 0.");
                   8073:       }
                   8074:       numlinepar++;
                   8075:       printf("\n");
                   8076:       fprintf(ficparo,"\n");
                   8077:     }
                   8078:   }
                   8079:   printf("# Covariance matrix\n");
                   8080: /* # 121 Var(a12)\n\ */
                   8081: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8082: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8083: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8084: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8085: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8086: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8087: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8088:   fflush(stdout);
                   8089:   fprintf(ficparo,"# Covariance matrix\n");
                   8090:   /* # 121 Var(a12)\n\ */
                   8091:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8092:   /* #   ...\n\ */
                   8093:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8094:   
                   8095:   for(itimes=1;itimes<=2;itimes++){
                   8096:     jj=0;
                   8097:     for(i=1; i <=nlstate; i++){
                   8098:       for(j=1; j <=nlstate+ndeath; j++){
                   8099:        if(j==i) continue;
                   8100:        for(k=1; k<=ncovmodel;k++){
                   8101:          jj++;
                   8102:          ca[0]= k+'a'-1;ca[1]='\0';
                   8103:          if(itimes==1){
                   8104:            printf("#%1d%1d%d",i,j,k);
                   8105:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8106:          }else{
                   8107:            printf("%1d%1d%d",i,j,k);
                   8108:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8109:            /*  printf(" %.5le",matcov[i][j]); */
                   8110:          }
                   8111:          ll=0;
                   8112:          for(li=1;li <=nlstate; li++){
                   8113:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8114:              if(lj==li) continue;
                   8115:              for(lk=1;lk<=ncovmodel;lk++){
                   8116:                ll++;
                   8117:                if(ll<=jj){
                   8118:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8119:                  if(ll<jj){
                   8120:                    if(itimes==1){
                   8121:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8122:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8123:                    }else{
                   8124:                      printf(" 0.");
                   8125:                      fprintf(ficparo," 0.");
                   8126:                    }
                   8127:                  }else{
                   8128:                    if(itimes==1){
                   8129:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8130:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8131:                    }else{
                   8132:                      printf(" 0.");
                   8133:                      fprintf(ficparo," 0.");
                   8134:                    }
                   8135:                  }
                   8136:                }
                   8137:              } /* end lk */
                   8138:            } /* end lj */
                   8139:          } /* end li */
                   8140:          printf("\n");
                   8141:          fprintf(ficparo,"\n");
                   8142:          numlinepar++;
                   8143:        } /* end k*/
                   8144:       } /*end j */
                   8145:     } /* end i */
                   8146:   } /* end itimes */
                   8147: 
                   8148: } /* end of prwizard */
                   8149: /******************* Gompertz Likelihood ******************************/
                   8150: double gompertz(double x[])
                   8151: { 
                   8152:   double A,B,L=0.0,sump=0.,num=0.;
                   8153:   int i,n=0; /* n is the size of the sample */
                   8154: 
1.220     brouard  8155:   for (i=1;i<=imx ; i++) {
1.126     brouard  8156:     sump=sump+weight[i];
                   8157:     /*    sump=sump+1;*/
                   8158:     num=num+1;
                   8159:   }
                   8160:  
                   8161:  
                   8162:   /* for (i=0; i<=imx; i++) 
                   8163:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8164: 
                   8165:   for (i=1;i<=imx ; i++)
                   8166:     {
                   8167:       if (cens[i] == 1 && wav[i]>1)
                   8168:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8169:       
                   8170:       if (cens[i] == 0 && wav[i]>1)
                   8171:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8172:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8173:       
                   8174:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8175:       if (wav[i] > 1 ) { /* ??? */
                   8176:        L=L+A*weight[i];
                   8177:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8178:       }
                   8179:     }
                   8180: 
                   8181:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8182:  
                   8183:   return -2*L*num/sump;
                   8184: }
                   8185: 
1.136     brouard  8186: #ifdef GSL
                   8187: /******************* Gompertz_f Likelihood ******************************/
                   8188: double gompertz_f(const gsl_vector *v, void *params)
                   8189: { 
                   8190:   double A,B,LL=0.0,sump=0.,num=0.;
                   8191:   double *x= (double *) v->data;
                   8192:   int i,n=0; /* n is the size of the sample */
                   8193: 
                   8194:   for (i=0;i<=imx-1 ; i++) {
                   8195:     sump=sump+weight[i];
                   8196:     /*    sump=sump+1;*/
                   8197:     num=num+1;
                   8198:   }
                   8199:  
                   8200:  
                   8201:   /* for (i=0; i<=imx; i++) 
                   8202:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8203:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8204:   for (i=1;i<=imx ; i++)
                   8205:     {
                   8206:       if (cens[i] == 1 && wav[i]>1)
                   8207:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8208:       
                   8209:       if (cens[i] == 0 && wav[i]>1)
                   8210:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8211:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8212:       
                   8213:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8214:       if (wav[i] > 1 ) { /* ??? */
                   8215:        LL=LL+A*weight[i];
                   8216:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8217:       }
                   8218:     }
                   8219: 
                   8220:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8221:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8222:  
                   8223:   return -2*LL*num/sump;
                   8224: }
                   8225: #endif
                   8226: 
1.126     brouard  8227: /******************* Printing html file ***********/
1.201     brouard  8228: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8229:                  int lastpass, int stepm, int weightopt, char model[],\
                   8230:                  int imx,  double p[],double **matcov,double agemortsup){
                   8231:   int i,k;
                   8232: 
                   8233:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8234:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8235:   for (i=1;i<=2;i++) 
                   8236:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8237:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8238:   fprintf(fichtm,"</ul>");
                   8239: 
                   8240: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8241: 
                   8242:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8243: 
                   8244:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8245:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8246: 
                   8247:  
                   8248:   fflush(fichtm);
                   8249: }
                   8250: 
                   8251: /******************* Gnuplot file **************/
1.201     brouard  8252: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8253: 
                   8254:   char dirfileres[132],optfileres[132];
1.164     brouard  8255: 
1.126     brouard  8256:   int ng;
                   8257: 
                   8258: 
                   8259:   /*#ifdef windows */
                   8260:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8261:     /*#endif */
                   8262: 
                   8263: 
                   8264:   strcpy(dirfileres,optionfilefiname);
                   8265:   strcpy(optfileres,"vpl");
1.199     brouard  8266:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8267:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8268:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8269:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8270:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8271: 
                   8272: } 
                   8273: 
1.136     brouard  8274: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8275: {
1.126     brouard  8276: 
1.136     brouard  8277:   /*-------- data file ----------*/
                   8278:   FILE *fic;
                   8279:   char dummy[]="                         ";
1.240     brouard  8280:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8281:   int lstra;
1.136     brouard  8282:   int linei, month, year,iout;
                   8283:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8284:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8285:   char *stratrunc;
1.223     brouard  8286: 
1.240     brouard  8287:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8288:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8289: 
1.240     brouard  8290:   for(v=1; v <=ncovcol;v++){
                   8291:     DummyV[v]=0;
                   8292:     FixedV[v]=0;
                   8293:   }
                   8294:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8295:     DummyV[v]=1;
                   8296:     FixedV[v]=0;
                   8297:   }
                   8298:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8299:     DummyV[v]=0;
                   8300:     FixedV[v]=1;
                   8301:   }
                   8302:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8303:     DummyV[v]=1;
                   8304:     FixedV[v]=1;
                   8305:   }
                   8306:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8307:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8308:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8309:   }
1.126     brouard  8310: 
1.136     brouard  8311:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8312:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8313:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8314:   }
1.126     brouard  8315: 
1.136     brouard  8316:   i=1;
                   8317:   linei=0;
                   8318:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8319:     linei=linei+1;
                   8320:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8321:       if(line[j] == '\t')
                   8322:        line[j] = ' ';
                   8323:     }
                   8324:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8325:       ;
                   8326:     };
                   8327:     line[j+1]=0;  /* Trims blanks at end of line */
                   8328:     if(line[0]=='#'){
                   8329:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8330:       printf("Comment line\n%s\n",line);
                   8331:       continue;
                   8332:     }
                   8333:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8334:     strcpy(line, linetmp);
1.223     brouard  8335:     
                   8336:     /* Loops on waves */
                   8337:     for (j=maxwav;j>=1;j--){
                   8338:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8339:        cutv(stra, strb, line, ' '); 
                   8340:        if(strb[0]=='.') { /* Missing value */
                   8341:          lval=-1;
                   8342:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8343:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8344:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8345:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8346:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8347:            return 1;
                   8348:          }
                   8349:        }else{
                   8350:          errno=0;
                   8351:          /* what_kind_of_number(strb); */
                   8352:          dval=strtod(strb,&endptr); 
                   8353:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8354:          /* if(strb != endptr && *endptr == '\0') */
                   8355:          /*    dval=dlval; */
                   8356:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8357:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8358:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8359:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8360:            return 1;
                   8361:          }
                   8362:          cotqvar[j][iv][i]=dval; 
                   8363:          cotvar[j][ntv+iv][i]=dval; 
                   8364:        }
                   8365:        strcpy(line,stra);
1.223     brouard  8366:       }/* end loop ntqv */
1.225     brouard  8367:       
1.223     brouard  8368:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8369:        cutv(stra, strb, line, ' '); 
                   8370:        if(strb[0]=='.') { /* Missing value */
                   8371:          lval=-1;
                   8372:        }else{
                   8373:          errno=0;
                   8374:          lval=strtol(strb,&endptr,10); 
                   8375:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8376:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8377:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8378:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8379:            return 1;
                   8380:          }
                   8381:        }
                   8382:        if(lval <-1 || lval >1){
                   8383:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8384:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8385:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8386:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8387:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8388:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8389:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8390:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8391:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8392:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8393:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8394:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8395:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8396:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8397:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8398:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8399:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8400:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8401:          return 1;
                   8402:        }
                   8403:        cotvar[j][iv][i]=(double)(lval);
                   8404:        strcpy(line,stra);
1.223     brouard  8405:       }/* end loop ntv */
1.225     brouard  8406:       
1.223     brouard  8407:       /* Statuses  at wave */
1.137     brouard  8408:       cutv(stra, strb, line, ' '); 
1.223     brouard  8409:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8410:        lval=-1;
1.136     brouard  8411:       }else{
1.238     brouard  8412:        errno=0;
                   8413:        lval=strtol(strb,&endptr,10); 
                   8414:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8415:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8416:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8417:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8418:          return 1;
                   8419:        }
1.136     brouard  8420:       }
1.225     brouard  8421:       
1.136     brouard  8422:       s[j][i]=lval;
1.225     brouard  8423:       
1.223     brouard  8424:       /* Date of Interview */
1.136     brouard  8425:       strcpy(line,stra);
                   8426:       cutv(stra, strb,line,' ');
1.169     brouard  8427:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8428:       }
1.169     brouard  8429:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8430:        month=99;
                   8431:        year=9999;
1.136     brouard  8432:       }else{
1.225     brouard  8433:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8434:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8435:        return 1;
1.136     brouard  8436:       }
                   8437:       anint[j][i]= (double) year; 
                   8438:       mint[j][i]= (double)month; 
                   8439:       strcpy(line,stra);
1.223     brouard  8440:     } /* End loop on waves */
1.225     brouard  8441:     
1.223     brouard  8442:     /* Date of death */
1.136     brouard  8443:     cutv(stra, strb,line,' '); 
1.169     brouard  8444:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8445:     }
1.169     brouard  8446:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8447:       month=99;
                   8448:       year=9999;
                   8449:     }else{
1.141     brouard  8450:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8451:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8452:       return 1;
1.136     brouard  8453:     }
                   8454:     andc[i]=(double) year; 
                   8455:     moisdc[i]=(double) month; 
                   8456:     strcpy(line,stra);
                   8457:     
1.223     brouard  8458:     /* Date of birth */
1.136     brouard  8459:     cutv(stra, strb,line,' '); 
1.169     brouard  8460:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8461:     }
1.169     brouard  8462:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8463:       month=99;
                   8464:       year=9999;
                   8465:     }else{
1.141     brouard  8466:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8467:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8468:       return 1;
1.136     brouard  8469:     }
                   8470:     if (year==9999) {
1.141     brouard  8471:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8472:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8473:       return 1;
                   8474:       
1.136     brouard  8475:     }
                   8476:     annais[i]=(double)(year);
                   8477:     moisnais[i]=(double)(month); 
                   8478:     strcpy(line,stra);
1.225     brouard  8479:     
1.223     brouard  8480:     /* Sample weight */
1.136     brouard  8481:     cutv(stra, strb,line,' '); 
                   8482:     errno=0;
                   8483:     dval=strtod(strb,&endptr); 
                   8484:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8485:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8486:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8487:       fflush(ficlog);
                   8488:       return 1;
                   8489:     }
                   8490:     weight[i]=dval; 
                   8491:     strcpy(line,stra);
1.225     brouard  8492:     
1.223     brouard  8493:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8494:       cutv(stra, strb, line, ' '); 
                   8495:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8496:        lval=-1;
1.223     brouard  8497:       }else{
1.225     brouard  8498:        errno=0;
                   8499:        /* what_kind_of_number(strb); */
                   8500:        dval=strtod(strb,&endptr);
                   8501:        /* if(strb != endptr && *endptr == '\0') */
                   8502:        /*   dval=dlval; */
                   8503:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8504:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8505:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8506:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8507:          return 1;
                   8508:        }
                   8509:        coqvar[iv][i]=dval; 
1.226     brouard  8510:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8511:       }
                   8512:       strcpy(line,stra);
                   8513:     }/* end loop nqv */
1.136     brouard  8514:     
1.223     brouard  8515:     /* Covariate values */
1.136     brouard  8516:     for (j=ncovcol;j>=1;j--){
                   8517:       cutv(stra, strb,line,' '); 
1.223     brouard  8518:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8519:        lval=-1;
1.136     brouard  8520:       }else{
1.225     brouard  8521:        errno=0;
                   8522:        lval=strtol(strb,&endptr,10); 
                   8523:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8524:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8525:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8526:          return 1;
                   8527:        }
1.136     brouard  8528:       }
                   8529:       if(lval <-1 || lval >1){
1.225     brouard  8530:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8531:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8532:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8533:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8534:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8535:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8536:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8537:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8538:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8539:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8540:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8541:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8542:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8543:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8544:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8545:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8546:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8547:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8548:        return 1;
1.136     brouard  8549:       }
                   8550:       covar[j][i]=(double)(lval);
                   8551:       strcpy(line,stra);
                   8552:     }  
                   8553:     lstra=strlen(stra);
1.225     brouard  8554:     
1.136     brouard  8555:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8556:       stratrunc = &(stra[lstra-9]);
                   8557:       num[i]=atol(stratrunc);
                   8558:     }
                   8559:     else
                   8560:       num[i]=atol(stra);
                   8561:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8562:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8563:     
                   8564:     i=i+1;
                   8565:   } /* End loop reading  data */
1.225     brouard  8566:   
1.136     brouard  8567:   *imax=i-1; /* Number of individuals */
                   8568:   fclose(fic);
1.225     brouard  8569:   
1.136     brouard  8570:   return (0);
1.164     brouard  8571:   /* endread: */
1.225     brouard  8572:   printf("Exiting readdata: ");
                   8573:   fclose(fic);
                   8574:   return (1);
1.223     brouard  8575: }
1.126     brouard  8576: 
1.234     brouard  8577: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8578:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8579:   while (*p2 == ' ')
1.234     brouard  8580:     p2++; 
                   8581:   /* while ((*p1++ = *p2++) !=0) */
                   8582:   /*   ; */
                   8583:   /* do */
                   8584:   /*   while (*p2 == ' ') */
                   8585:   /*     p2++; */
                   8586:   /* while (*p1++ == *p2++); */
                   8587:   *stri=p2; 
1.145     brouard  8588: }
                   8589: 
1.235     brouard  8590: int decoderesult ( char resultline[], int nres)
1.230     brouard  8591: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8592: {
1.235     brouard  8593:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8594:   char resultsav[MAXLINE];
1.234     brouard  8595:   int resultmodel[MAXLINE];
                   8596:   int modelresult[MAXLINE];
1.230     brouard  8597:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8598: 
1.234     brouard  8599:   removefirstspace(&resultline);
1.233     brouard  8600:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8601: 
                   8602:   if (strstr(resultline,"v") !=0){
                   8603:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8604:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8605:     return 1;
                   8606:   }
                   8607:   trimbb(resultsav, resultline);
                   8608:   if (strlen(resultsav) >1){
                   8609:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8610:   }
1.253     brouard  8611:   if(j == 0){ /* Resultline but no = */
                   8612:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8613:     return (0);
                   8614:   }
                   8615:     
1.234     brouard  8616:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8617:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8618:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8619:   }
                   8620:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8621:     if(nbocc(resultsav,'=') >1){
                   8622:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8623:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8624:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8625:     }else
                   8626:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8627:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8628:     
1.230     brouard  8629:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8630:     Tvarsel[k]=atoi(strc);
                   8631:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8632:     /* cptcovsel++;     */
                   8633:     if (nbocc(stra,'=') >0)
                   8634:       strcpy(resultsav,stra); /* and analyzes it */
                   8635:   }
1.235     brouard  8636:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8637:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8638:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8639:       match=0;
1.236     brouard  8640:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8641:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8642:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8643:          match=1;
                   8644:          break;
                   8645:        }
                   8646:       }
                   8647:       if(match == 0){
                   8648:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8649:       }
                   8650:     }
                   8651:   }
1.235     brouard  8652:   /* Checking for missing or useless values in comparison of current model needs */
                   8653:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8654:     match=0;
1.235     brouard  8655:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8656:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8657:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8658:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8659:          ++match;
                   8660:        }
                   8661:       }
                   8662:     }
                   8663:     if(match == 0){
                   8664:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8665:     }else if(match > 1){
                   8666:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8667:     }
                   8668:   }
1.235     brouard  8669:       
1.234     brouard  8670:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8671:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8672:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8673:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8674:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8675:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8676:   /*    1 0 0 0 */
                   8677:   /*    2 1 0 0 */
                   8678:   /*    3 0 1 0 */ 
                   8679:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8680:   /*    5 0 0 1 */
                   8681:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8682:   /*    7 0 1 1 */
                   8683:   /*    8 1 1 1 */
1.237     brouard  8684:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8685:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8686:   /* V5*age V5 known which value for nres?  */
                   8687:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8688:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8689:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8690:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8691:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8692:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8693:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8694:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8695:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8696:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8697:       k4++;;
                   8698:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8699:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8700:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8701:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8702:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8703:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8704:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8705:       k4q++;;
                   8706:     }
                   8707:   }
1.234     brouard  8708:   
1.235     brouard  8709:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8710:   return (0);
                   8711: }
1.235     brouard  8712: 
1.230     brouard  8713: int decodemodel( char model[], int lastobs)
                   8714:  /**< This routine decodes the model and returns:
1.224     brouard  8715:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8716:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8717:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8718:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8719:        * - cptcovage number of covariates with age*products =2
                   8720:        * - cptcovs number of simple covariates
                   8721:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8722:        *     which is a new column after the 9 (ncovcol) variables. 
                   8723:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8724:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8725:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8726:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8727:        */
1.136     brouard  8728: {
1.238     brouard  8729:   int i, j, k, ks, v;
1.227     brouard  8730:   int  j1, k1, k2, k3, k4;
1.136     brouard  8731:   char modelsav[80];
1.145     brouard  8732:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8733:   char *strpt;
1.136     brouard  8734: 
1.145     brouard  8735:   /*removespace(model);*/
1.136     brouard  8736:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8737:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8738:     if (strstr(model,"AGE") !=0){
1.192     brouard  8739:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8740:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8741:       return 1;
                   8742:     }
1.141     brouard  8743:     if (strstr(model,"v") !=0){
                   8744:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8745:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8746:       return 1;
                   8747:     }
1.187     brouard  8748:     strcpy(modelsav,model); 
                   8749:     if ((strpt=strstr(model,"age*age")) !=0){
                   8750:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8751:       if(strpt != model){
1.234     brouard  8752:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8753:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8754:  corresponding column of parameters.\n",model);
1.234     brouard  8755:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8756:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8757:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8758:        return 1;
1.225     brouard  8759:       }
1.187     brouard  8760:       nagesqr=1;
                   8761:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8762:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8763:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8764:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8765:       else 
1.234     brouard  8766:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8767:     }else
                   8768:       nagesqr=0;
                   8769:     if (strlen(modelsav) >1){
                   8770:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8771:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8772:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8773:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8774:                     * cst, age and age*age 
                   8775:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8776:       /* including age products which are counted in cptcovage.
                   8777:        * but the covariates which are products must be treated 
                   8778:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8779:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8780:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8781:       
                   8782:       
1.187     brouard  8783:       /*   Design
                   8784:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8785:        *  <          ncovcol=8                >
                   8786:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8787:        *   k=  1    2      3       4     5       6      7        8
                   8788:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8789:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8790:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8791:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8792:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8793:        *  Tage[++cptcovage]=k
                   8794:        *       if products, new covar are created after ncovcol with k1
                   8795:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8796:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8797:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8798:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8799:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8800:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8801:        *  <          ncovcol=8                >
                   8802:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8803:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8804:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8805:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8806:        * p Tprod[1]@2={                         6, 5}
                   8807:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8808:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8809:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8810:        *How to reorganize?
                   8811:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8812:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8813:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8814:        * Struct []
                   8815:        */
1.225     brouard  8816:       
1.187     brouard  8817:       /* This loop fills the array Tvar from the string 'model'.*/
                   8818:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8819:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8820:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8821:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8822:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8823:       /*       k=1 Tvar[1]=2 (from V2) */
                   8824:       /*       k=5 Tvar[5] */
                   8825:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8826:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8827:       /*       } */
1.198     brouard  8828:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8829:       /*
                   8830:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8831:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8832:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8833:       }
1.187     brouard  8834:       cptcovage=0;
                   8835:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8836:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8837:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8838:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8839:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8840:        /*scanf("%d",i);*/
                   8841:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8842:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8843:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8844:            /* covar is not filled and then is empty */
                   8845:            cptcovprod--;
                   8846:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8847:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8848:            Typevar[k]=1;  /* 1 for age product */
                   8849:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8850:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8851:            /*printf("stre=%s ", stre);*/
                   8852:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8853:            cptcovprod--;
                   8854:            cutl(stre,strb,strc,'V');
                   8855:            Tvar[k]=atoi(stre);
                   8856:            Typevar[k]=1;  /* 1 for age product */
                   8857:            cptcovage++;
                   8858:            Tage[cptcovage]=k;
                   8859:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8860:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8861:            cptcovn++;
                   8862:            cptcovprodnoage++;k1++;
                   8863:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8864:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8865:                                                because this model-covariate is a construction we invent a new column
                   8866:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8867:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8868:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8869:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8870:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8871:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8872:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8873:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8874:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8875:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8876:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8877:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8878:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8879:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8880:            for (i=1; i<=lastobs;i++){
                   8881:              /* Computes the new covariate which is a product of
                   8882:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8883:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8884:            }
                   8885:          } /* End age is not in the model */
                   8886:        } /* End if model includes a product */
                   8887:        else { /* no more sum */
                   8888:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8889:          /*  scanf("%d",i);*/
                   8890:          cutl(strd,strc,strb,'V');
                   8891:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8892:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8893:          Tvar[k]=atoi(strd);
                   8894:          Typevar[k]=0;  /* 0 for simple covariates */
                   8895:        }
                   8896:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8897:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8898:                                  scanf("%d",i);*/
1.187     brouard  8899:       } /* end of loop + on total covariates */
                   8900:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8901:   } /* end if strlen(model == 0) */
1.136     brouard  8902:   
                   8903:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8904:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8905:   
1.136     brouard  8906:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8907:      printf("cptcovprod=%d ", cptcovprod);
                   8908:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8909:      scanf("%d ",i);*/
                   8910: 
                   8911: 
1.230     brouard  8912: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8913:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8914: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8915:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8916:    k =           1    2   3     4       5       6      7      8        9
                   8917:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8918:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8919:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8920:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8921:          Tmodelind[combination of covar]=k;
1.225     brouard  8922: */  
                   8923: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8924:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8925:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8926:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8927:   printf("Model=%s\n\
                   8928: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8929: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8930: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8931:   fprintf(ficlog,"Model=%s\n\
                   8932: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8933: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8934: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8935:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8936:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8937:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8938:       Fixed[k]= 0;
                   8939:       Dummy[k]= 0;
1.225     brouard  8940:       ncoveff++;
1.232     brouard  8941:       ncovf++;
1.234     brouard  8942:       nsd++;
                   8943:       modell[k].maintype= FTYPE;
                   8944:       TvarsD[nsd]=Tvar[k];
                   8945:       TvarsDind[nsd]=k;
                   8946:       TvarF[ncovf]=Tvar[k];
                   8947:       TvarFind[ncovf]=k;
                   8948:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8949:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8950:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8951:       Fixed[k]= 0;
                   8952:       Dummy[k]= 0;
                   8953:       ncoveff++;
                   8954:       ncovf++;
                   8955:       modell[k].maintype= FTYPE;
                   8956:       TvarF[ncovf]=Tvar[k];
                   8957:       TvarFind[ncovf]=k;
1.230     brouard  8958:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8959:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8960:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8961:       Fixed[k]= 0;
                   8962:       Dummy[k]= 1;
1.230     brouard  8963:       nqfveff++;
1.234     brouard  8964:       modell[k].maintype= FTYPE;
                   8965:       modell[k].subtype= FQ;
                   8966:       nsq++;
                   8967:       TvarsQ[nsq]=Tvar[k];
                   8968:       TvarsQind[nsq]=k;
1.232     brouard  8969:       ncovf++;
1.234     brouard  8970:       TvarF[ncovf]=Tvar[k];
                   8971:       TvarFind[ncovf]=k;
1.231     brouard  8972:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8973:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8974:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8975:       Fixed[k]= 1;
                   8976:       Dummy[k]= 0;
1.225     brouard  8977:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8978:       modell[k].maintype= VTYPE;
                   8979:       modell[k].subtype= VD;
                   8980:       nsd++;
                   8981:       TvarsD[nsd]=Tvar[k];
                   8982:       TvarsDind[nsd]=k;
                   8983:       ncovv++; /* Only simple time varying variables */
                   8984:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8985:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8986:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8987:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8988:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8989:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8990:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8991:       Fixed[k]= 1;
                   8992:       Dummy[k]= 1;
                   8993:       nqtveff++;
                   8994:       modell[k].maintype= VTYPE;
                   8995:       modell[k].subtype= VQ;
                   8996:       ncovv++; /* Only simple time varying variables */
                   8997:       nsq++;
                   8998:       TvarsQ[nsq]=Tvar[k];
                   8999:       TvarsQind[nsq]=k;
                   9000:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9001:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9002:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9003:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9004:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9005:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9006:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9007:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9008:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9009:       ncova++;
                   9010:       TvarA[ncova]=Tvar[k];
                   9011:       TvarAind[ncova]=k;
1.231     brouard  9012:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9013:        Fixed[k]= 2;
                   9014:        Dummy[k]= 2;
                   9015:        modell[k].maintype= ATYPE;
                   9016:        modell[k].subtype= APFD;
                   9017:        /* ncoveff++; */
1.227     brouard  9018:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9019:        Fixed[k]= 2;
                   9020:        Dummy[k]= 3;
                   9021:        modell[k].maintype= ATYPE;
                   9022:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9023:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9024:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9025:        Fixed[k]= 3;
                   9026:        Dummy[k]= 2;
                   9027:        modell[k].maintype= ATYPE;
                   9028:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9029:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9030:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9031:        Fixed[k]= 3;
                   9032:        Dummy[k]= 3;
                   9033:        modell[k].maintype= ATYPE;
                   9034:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9035:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9036:       }
                   9037:     }else if (Typevar[k] == 2) {  /* product without age */
                   9038:       k1=Tposprod[k];
                   9039:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9040:        if(Tvard[k1][2] <=ncovcol){
                   9041:          Fixed[k]= 1;
                   9042:          Dummy[k]= 0;
                   9043:          modell[k].maintype= FTYPE;
                   9044:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9045:          ncovf++; /* Fixed variables without age */
                   9046:          TvarF[ncovf]=Tvar[k];
                   9047:          TvarFind[ncovf]=k;
                   9048:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9049:          Fixed[k]= 0;  /* or 2 ?*/
                   9050:          Dummy[k]= 1;
                   9051:          modell[k].maintype= FTYPE;
                   9052:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9053:          ncovf++; /* Varying variables without age */
                   9054:          TvarF[ncovf]=Tvar[k];
                   9055:          TvarFind[ncovf]=k;
                   9056:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9057:          Fixed[k]= 1;
                   9058:          Dummy[k]= 0;
                   9059:          modell[k].maintype= VTYPE;
                   9060:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9061:          ncovv++; /* Varying variables without age */
                   9062:          TvarV[ncovv]=Tvar[k];
                   9063:          TvarVind[ncovv]=k;
                   9064:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9065:          Fixed[k]= 1;
                   9066:          Dummy[k]= 1;
                   9067:          modell[k].maintype= VTYPE;
                   9068:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9069:          ncovv++; /* Varying variables without age */
                   9070:          TvarV[ncovv]=Tvar[k];
                   9071:          TvarVind[ncovv]=k;
                   9072:        }
1.227     brouard  9073:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9074:        if(Tvard[k1][2] <=ncovcol){
                   9075:          Fixed[k]= 0;  /* or 2 ?*/
                   9076:          Dummy[k]= 1;
                   9077:          modell[k].maintype= FTYPE;
                   9078:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9079:          ncovf++; /* Fixed variables without age */
                   9080:          TvarF[ncovf]=Tvar[k];
                   9081:          TvarFind[ncovf]=k;
                   9082:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9083:          Fixed[k]= 1;
                   9084:          Dummy[k]= 1;
                   9085:          modell[k].maintype= VTYPE;
                   9086:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9087:          ncovv++; /* Varying variables without age */
                   9088:          TvarV[ncovv]=Tvar[k];
                   9089:          TvarVind[ncovv]=k;
                   9090:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9091:          Fixed[k]= 1;
                   9092:          Dummy[k]= 1;
                   9093:          modell[k].maintype= VTYPE;
                   9094:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9095:          ncovv++; /* Varying variables without age */
                   9096:          TvarV[ncovv]=Tvar[k];
                   9097:          TvarVind[ncovv]=k;
                   9098:          ncovv++; /* Varying variables without age */
                   9099:          TvarV[ncovv]=Tvar[k];
                   9100:          TvarVind[ncovv]=k;
                   9101:        }
1.227     brouard  9102:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9103:        if(Tvard[k1][2] <=ncovcol){
                   9104:          Fixed[k]= 1;
                   9105:          Dummy[k]= 1;
                   9106:          modell[k].maintype= VTYPE;
                   9107:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9108:          ncovv++; /* Varying variables without age */
                   9109:          TvarV[ncovv]=Tvar[k];
                   9110:          TvarVind[ncovv]=k;
                   9111:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9112:          Fixed[k]= 1;
                   9113:          Dummy[k]= 1;
                   9114:          modell[k].maintype= VTYPE;
                   9115:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9116:          ncovv++; /* Varying variables without age */
                   9117:          TvarV[ncovv]=Tvar[k];
                   9118:          TvarVind[ncovv]=k;
                   9119:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9120:          Fixed[k]= 1;
                   9121:          Dummy[k]= 0;
                   9122:          modell[k].maintype= VTYPE;
                   9123:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9124:          ncovv++; /* Varying variables without age */
                   9125:          TvarV[ncovv]=Tvar[k];
                   9126:          TvarVind[ncovv]=k;
                   9127:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9128:          Fixed[k]= 1;
                   9129:          Dummy[k]= 1;
                   9130:          modell[k].maintype= VTYPE;
                   9131:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9132:          ncovv++; /* Varying variables without age */
                   9133:          TvarV[ncovv]=Tvar[k];
                   9134:          TvarVind[ncovv]=k;
                   9135:        }
1.227     brouard  9136:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9137:        if(Tvard[k1][2] <=ncovcol){
                   9138:          Fixed[k]= 1;
                   9139:          Dummy[k]= 1;
                   9140:          modell[k].maintype= VTYPE;
                   9141:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9142:          ncovv++; /* Varying variables without age */
                   9143:          TvarV[ncovv]=Tvar[k];
                   9144:          TvarVind[ncovv]=k;
                   9145:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9146:          Fixed[k]= 1;
                   9147:          Dummy[k]= 1;
                   9148:          modell[k].maintype= VTYPE;
                   9149:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9150:          ncovv++; /* Varying variables without age */
                   9151:          TvarV[ncovv]=Tvar[k];
                   9152:          TvarVind[ncovv]=k;
                   9153:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9154:          Fixed[k]= 1;
                   9155:          Dummy[k]= 1;
                   9156:          modell[k].maintype= VTYPE;
                   9157:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9158:          ncovv++; /* Varying variables without age */
                   9159:          TvarV[ncovv]=Tvar[k];
                   9160:          TvarVind[ncovv]=k;
                   9161:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9162:          Fixed[k]= 1;
                   9163:          Dummy[k]= 1;
                   9164:          modell[k].maintype= VTYPE;
                   9165:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9166:          ncovv++; /* Varying variables without age */
                   9167:          TvarV[ncovv]=Tvar[k];
                   9168:          TvarVind[ncovv]=k;
                   9169:        }
1.227     brouard  9170:       }else{
1.240     brouard  9171:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9172:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9173:       } /*end k1*/
1.225     brouard  9174:     }else{
1.226     brouard  9175:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9176:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9177:     }
1.227     brouard  9178:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9179:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9180:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9181:   }
                   9182:   /* Searching for doublons in the model */
                   9183:   for(k1=1; k1<= cptcovt;k1++){
                   9184:     for(k2=1; k2 <k1;k2++){
                   9185:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9186:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9187:          if(Tvar[k1]==Tvar[k2]){
                   9188:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9189:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9190:            return(1);
                   9191:          }
                   9192:        }else if (Typevar[k1] ==2){
                   9193:          k3=Tposprod[k1];
                   9194:          k4=Tposprod[k2];
                   9195:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9196:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9197:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9198:            return(1);
                   9199:          }
                   9200:        }
1.227     brouard  9201:       }
                   9202:     }
1.225     brouard  9203:   }
                   9204:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9205:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9206:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9207:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9208:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9209:   /*endread:*/
1.225     brouard  9210:   printf("Exiting decodemodel: ");
                   9211:   return (1);
1.136     brouard  9212: }
                   9213: 
1.169     brouard  9214: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9215: {/* Check ages at death */
1.136     brouard  9216:   int i, m;
1.218     brouard  9217:   int firstone=0;
                   9218:   
1.136     brouard  9219:   for (i=1; i<=imx; i++) {
                   9220:     for(m=2; (m<= maxwav); m++) {
                   9221:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9222:        anint[m][i]=9999;
1.216     brouard  9223:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9224:          s[m][i]=-1;
1.136     brouard  9225:       }
                   9226:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9227:        *nberr = *nberr + 1;
1.218     brouard  9228:        if(firstone == 0){
                   9229:          firstone=1;
1.260     brouard  9230:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9231:        }
1.262     brouard  9232:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9233:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9234:       }
                   9235:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9236:        (*nberr)++;
1.259     brouard  9237:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9238:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9239:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9240:       }
                   9241:     }
                   9242:   }
                   9243: 
                   9244:   for (i=1; i<=imx; i++)  {
                   9245:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9246:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9247:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9248:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9249:          if(agedc[i]>0){
                   9250:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9251:              agev[m][i]=agedc[i];
1.214     brouard  9252:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9253:            }else {
1.136     brouard  9254:              if ((int)andc[i]!=9999){
                   9255:                nbwarn++;
                   9256:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9257:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9258:                agev[m][i]=-1;
                   9259:              }
                   9260:            }
1.169     brouard  9261:          } /* agedc > 0 */
1.214     brouard  9262:        } /* end if */
1.136     brouard  9263:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9264:                                 years but with the precision of a month */
                   9265:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9266:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9267:            agev[m][i]=1;
                   9268:          else if(agev[m][i] < *agemin){ 
                   9269:            *agemin=agev[m][i];
                   9270:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9271:          }
                   9272:          else if(agev[m][i] >*agemax){
                   9273:            *agemax=agev[m][i];
1.156     brouard  9274:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9275:          }
                   9276:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9277:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9278:        } /* en if 9*/
1.136     brouard  9279:        else { /* =9 */
1.214     brouard  9280:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9281:          agev[m][i]=1;
                   9282:          s[m][i]=-1;
                   9283:        }
                   9284:       }
1.214     brouard  9285:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9286:        agev[m][i]=1;
1.214     brouard  9287:       else{
                   9288:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9289:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9290:        agev[m][i]=0;
                   9291:       }
                   9292:     } /* End for lastpass */
                   9293:   }
1.136     brouard  9294:     
                   9295:   for (i=1; i<=imx; i++)  {
                   9296:     for(m=firstpass; (m<=lastpass); m++){
                   9297:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9298:        (*nberr)++;
1.136     brouard  9299:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9300:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9301:        return 1;
                   9302:       }
                   9303:     }
                   9304:   }
                   9305: 
                   9306:   /*for (i=1; i<=imx; i++){
                   9307:   for (m=firstpass; (m<lastpass); m++){
                   9308:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9309: }
                   9310: 
                   9311: }*/
                   9312: 
                   9313: 
1.139     brouard  9314:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9315:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9316: 
                   9317:   return (0);
1.164     brouard  9318:  /* endread:*/
1.136     brouard  9319:     printf("Exiting calandcheckages: ");
                   9320:     return (1);
                   9321: }
                   9322: 
1.172     brouard  9323: #if defined(_MSC_VER)
                   9324: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9325: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9326: //#include "stdafx.h"
                   9327: //#include <stdio.h>
                   9328: //#include <tchar.h>
                   9329: //#include <windows.h>
                   9330: //#include <iostream>
                   9331: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9332: 
                   9333: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9334: 
                   9335: BOOL IsWow64()
                   9336: {
                   9337:        BOOL bIsWow64 = FALSE;
                   9338: 
                   9339:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9340:        //  (HANDLE, PBOOL);
                   9341: 
                   9342:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9343: 
                   9344:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9345:        const char funcName[] = "IsWow64Process";
                   9346:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9347:                GetProcAddress(module, funcName);
                   9348: 
                   9349:        if (NULL != fnIsWow64Process)
                   9350:        {
                   9351:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9352:                        &bIsWow64))
                   9353:                        //throw std::exception("Unknown error");
                   9354:                        printf("Unknown error\n");
                   9355:        }
                   9356:        return bIsWow64 != FALSE;
                   9357: }
                   9358: #endif
1.177     brouard  9359: 
1.191     brouard  9360: void syscompilerinfo(int logged)
1.167     brouard  9361:  {
                   9362:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9363:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9364:    /* /GS /W3 /Gy
                   9365:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9366:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9367:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9368:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9369:    */ 
                   9370:    /* 64 bits */
1.185     brouard  9371:    /*
                   9372:      /GS /W3 /Gy
                   9373:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9374:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9375:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9376:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9377:    /* Optimization are useless and O3 is slower than O2 */
                   9378:    /*
                   9379:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9380:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9381:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9382:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9383:    */
1.186     brouard  9384:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9385:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9386:       /PDB:"visual studio
                   9387:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9388:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9389:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9390:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9391:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9392:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9393:       uiAccess='false'"
                   9394:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9395:       /NOLOGO /TLBID:1
                   9396:    */
1.177     brouard  9397: #if defined __INTEL_COMPILER
1.178     brouard  9398: #if defined(__GNUC__)
                   9399:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9400: #endif
1.177     brouard  9401: #elif defined(__GNUC__) 
1.179     brouard  9402: #ifndef  __APPLE__
1.174     brouard  9403: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9404: #endif
1.177     brouard  9405:    struct utsname sysInfo;
1.178     brouard  9406:    int cross = CROSS;
                   9407:    if (cross){
                   9408:           printf("Cross-");
1.191     brouard  9409:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9410:    }
1.174     brouard  9411: #endif
                   9412: 
1.171     brouard  9413: #include <stdint.h>
1.178     brouard  9414: 
1.191     brouard  9415:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9416: #if defined(__clang__)
1.191     brouard  9417:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9418: #endif
                   9419: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9420:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9421: #endif
                   9422: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9423:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9424: #endif
                   9425: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9426:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9427: #endif
                   9428: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9429:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9430: #endif
                   9431: #if defined(_MSC_VER)
1.191     brouard  9432:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9433: #endif
                   9434: #if defined(__PGI)
1.191     brouard  9435:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9436: #endif
                   9437: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9438:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9439: #endif
1.191     brouard  9440:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9441:    
1.167     brouard  9442: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9443: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9444:     // Windows (x64 and x86)
1.191     brouard  9445:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9446: #elif __unix__ // all unices, not all compilers
                   9447:     // Unix
1.191     brouard  9448:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9449: #elif __linux__
                   9450:     // linux
1.191     brouard  9451:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9452: #elif __APPLE__
1.174     brouard  9453:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9454:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9455: #endif
                   9456: 
                   9457: /*  __MINGW32__          */
                   9458: /*  __CYGWIN__  */
                   9459: /* __MINGW64__  */
                   9460: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9461: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9462: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9463: /* _WIN64  // Defined for applications for Win64. */
                   9464: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9465: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9466: 
1.167     brouard  9467: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9468:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9469: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9470:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9471: #else
1.191     brouard  9472:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9473: #endif
                   9474: 
1.169     brouard  9475: #if defined(__GNUC__)
                   9476: # if defined(__GNUC_PATCHLEVEL__)
                   9477: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9478:                             + __GNUC_MINOR__ * 100 \
                   9479:                             + __GNUC_PATCHLEVEL__)
                   9480: # else
                   9481: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9482:                             + __GNUC_MINOR__ * 100)
                   9483: # endif
1.174     brouard  9484:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9485:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9486: 
                   9487:    if (uname(&sysInfo) != -1) {
                   9488:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9489:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9490:    }
                   9491:    else
                   9492:       perror("uname() error");
1.179     brouard  9493:    //#ifndef __INTEL_COMPILER 
                   9494: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9495:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9496:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9497: #endif
1.169     brouard  9498: #endif
1.172     brouard  9499: 
                   9500:    //   void main()
                   9501:    //   {
1.169     brouard  9502: #if defined(_MSC_VER)
1.174     brouard  9503:    if (IsWow64()){
1.191     brouard  9504:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9505:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9506:    }
                   9507:    else{
1.191     brouard  9508:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9509:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9510:    }
1.172     brouard  9511:    //     printf("\nPress Enter to continue...");
                   9512:    //     getchar();
                   9513:    //   }
                   9514: 
1.169     brouard  9515: #endif
                   9516:    
1.167     brouard  9517: 
1.219     brouard  9518: }
1.136     brouard  9519: 
1.219     brouard  9520: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9521:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9522:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9523:   /* double ftolpl = 1.e-10; */
1.180     brouard  9524:   double age, agebase, agelim;
1.203     brouard  9525:   double tot;
1.180     brouard  9526: 
1.202     brouard  9527:   strcpy(filerespl,"PL_");
                   9528:   strcat(filerespl,fileresu);
                   9529:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9530:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9531:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9532:   }
1.227     brouard  9533:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9534:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9535:   pstamp(ficrespl);
1.203     brouard  9536:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9537:   fprintf(ficrespl,"#Age ");
                   9538:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9539:   fprintf(ficrespl,"\n");
1.180     brouard  9540:   
1.219     brouard  9541:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9542: 
1.219     brouard  9543:   agebase=ageminpar;
                   9544:   agelim=agemaxpar;
1.180     brouard  9545: 
1.227     brouard  9546:   /* i1=pow(2,ncoveff); */
1.234     brouard  9547:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9548:   if (cptcovn < 1){i1=1;}
1.180     brouard  9549: 
1.238     brouard  9550:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9551:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9552:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9553:        continue;
1.235     brouard  9554: 
1.238     brouard  9555:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9556:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9557:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9558:       /* k=k+1; */
                   9559:       /* to clean */
                   9560:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9561:       fprintf(ficrespl,"#******");
                   9562:       printf("#******");
                   9563:       fprintf(ficlog,"#******");
                   9564:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9565:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9566:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9567:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9568:       }
                   9569:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9570:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9571:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9572:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9573:       }
                   9574:       fprintf(ficrespl,"******\n");
                   9575:       printf("******\n");
                   9576:       fprintf(ficlog,"******\n");
                   9577:       if(invalidvarcomb[k]){
                   9578:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9579:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9580:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9581:        continue;
                   9582:       }
1.219     brouard  9583: 
1.238     brouard  9584:       fprintf(ficrespl,"#Age ");
                   9585:       for(j=1;j<=cptcoveff;j++) {
                   9586:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9587:       }
                   9588:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9589:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9590:     
1.238     brouard  9591:       for (age=agebase; age<=agelim; age++){
                   9592:        /* for (age=agebase; age<=agebase; age++){ */
                   9593:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9594:        fprintf(ficrespl,"%.0f ",age );
                   9595:        for(j=1;j<=cptcoveff;j++)
                   9596:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9597:        tot=0.;
                   9598:        for(i=1; i<=nlstate;i++){
                   9599:          tot +=  prlim[i][i];
                   9600:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9601:        }
                   9602:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9603:       } /* Age */
                   9604:       /* was end of cptcod */
                   9605:     } /* cptcov */
                   9606:   } /* nres */
1.219     brouard  9607:   return 0;
1.180     brouard  9608: }
                   9609: 
1.218     brouard  9610: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9611:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9612:        
                   9613:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9614:    * at any age between ageminpar and agemaxpar
                   9615:         */
1.235     brouard  9616:   int i, j, k, i1, nres=0 ;
1.217     brouard  9617:   /* double ftolpl = 1.e-10; */
                   9618:   double age, agebase, agelim;
                   9619:   double tot;
1.218     brouard  9620:   /* double ***mobaverage; */
                   9621:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9622: 
                   9623:   strcpy(fileresplb,"PLB_");
                   9624:   strcat(fileresplb,fileresu);
                   9625:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9626:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9627:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9628:   }
                   9629:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9630:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9631:   pstamp(ficresplb);
                   9632:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9633:   fprintf(ficresplb,"#Age ");
                   9634:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9635:   fprintf(ficresplb,"\n");
                   9636:   
1.218     brouard  9637:   
                   9638:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9639:   
                   9640:   agebase=ageminpar;
                   9641:   agelim=agemaxpar;
                   9642:   
                   9643:   
1.227     brouard  9644:   i1=pow(2,cptcoveff);
1.218     brouard  9645:   if (cptcovn < 1){i1=1;}
1.227     brouard  9646:   
1.238     brouard  9647:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9648:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9649:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9650:        continue;
                   9651:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9652:       fprintf(ficresplb,"#******");
                   9653:       printf("#******");
                   9654:       fprintf(ficlog,"#******");
                   9655:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9656:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9657:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9658:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9659:       }
                   9660:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9661:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9662:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9663:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9664:       }
                   9665:       fprintf(ficresplb,"******\n");
                   9666:       printf("******\n");
                   9667:       fprintf(ficlog,"******\n");
                   9668:       if(invalidvarcomb[k]){
                   9669:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9670:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9671:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9672:        continue;
                   9673:       }
1.218     brouard  9674:     
1.238     brouard  9675:       fprintf(ficresplb,"#Age ");
                   9676:       for(j=1;j<=cptcoveff;j++) {
                   9677:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9678:       }
                   9679:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9680:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9681:     
                   9682:     
1.238     brouard  9683:       for (age=agebase; age<=agelim; age++){
                   9684:        /* for (age=agebase; age<=agebase; age++){ */
                   9685:        if(mobilavproj > 0){
                   9686:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9687:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9688:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9689:        }else if (mobilavproj == 0){
                   9690:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9691:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9692:          exit(1);
                   9693:        }else{
                   9694:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9695:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9696:        }
                   9697:        fprintf(ficresplb,"%.0f ",age );
                   9698:        for(j=1;j<=cptcoveff;j++)
                   9699:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9700:        tot=0.;
                   9701:        for(i=1; i<=nlstate;i++){
                   9702:          tot +=  bprlim[i][i];
                   9703:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9704:        }
                   9705:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9706:       } /* Age */
                   9707:       /* was end of cptcod */
1.255     brouard  9708:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9709:     } /* end of any combination */
                   9710:   } /* end of nres */  
1.218     brouard  9711:   /* hBijx(p, bage, fage); */
                   9712:   /* fclose(ficrespijb); */
                   9713:   
                   9714:   return 0;
1.217     brouard  9715: }
1.218     brouard  9716:  
1.180     brouard  9717: int hPijx(double *p, int bage, int fage){
                   9718:     /*------------- h Pij x at various ages ------------*/
                   9719: 
                   9720:   int stepsize;
                   9721:   int agelim;
                   9722:   int hstepm;
                   9723:   int nhstepm;
1.235     brouard  9724:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9725: 
                   9726:   double agedeb;
                   9727:   double ***p3mat;
                   9728: 
1.201     brouard  9729:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9730:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9731:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9732:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9733:     }
                   9734:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9735:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9736:   
                   9737:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9738:     /*if (stepm<=24) stepsize=2;*/
                   9739: 
                   9740:     agelim=AGESUP;
                   9741:     hstepm=stepsize*YEARM; /* Every year of age */
                   9742:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9743:                
1.180     brouard  9744:     /* hstepm=1;   aff par mois*/
                   9745:     pstamp(ficrespij);
                   9746:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9747:     i1= pow(2,cptcoveff);
1.218     brouard  9748:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9749:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9750:                /*      k=k+1;  */
1.235     brouard  9751:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9752:     for(k=1; k<=i1;k++){
1.253     brouard  9753:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9754:        continue;
1.183     brouard  9755:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9756:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9757:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9758:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9759:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9760:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9761:       }
1.183     brouard  9762:       fprintf(ficrespij,"******\n");
                   9763:       
                   9764:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9765:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9766:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9767:        
                   9768:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9769:        
1.183     brouard  9770:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9771:        oldm=oldms;savm=savms;
1.235     brouard  9772:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9773:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9774:        for(i=1; i<=nlstate;i++)
                   9775:          for(j=1; j<=nlstate+ndeath;j++)
                   9776:            fprintf(ficrespij," %1d-%1d",i,j);
                   9777:        fprintf(ficrespij,"\n");
                   9778:        for (h=0; h<=nhstepm; h++){
                   9779:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9780:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9781:          for(i=1; i<=nlstate;i++)
                   9782:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9783:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9784:          fprintf(ficrespij,"\n");
                   9785:        }
1.183     brouard  9786:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9787:        fprintf(ficrespij,"\n");
                   9788:       }
1.180     brouard  9789:       /*}*/
                   9790:     }
1.218     brouard  9791:     return 0;
1.180     brouard  9792: }
1.218     brouard  9793:  
                   9794:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9795:     /*------------- h Bij x at various ages ------------*/
                   9796: 
                   9797:   int stepsize;
1.218     brouard  9798:   /* int agelim; */
                   9799:        int ageminl;
1.217     brouard  9800:   int hstepm;
                   9801:   int nhstepm;
1.238     brouard  9802:   int h, i, i1, j, k, nres;
1.218     brouard  9803:        
1.217     brouard  9804:   double agedeb;
                   9805:   double ***p3mat;
1.218     brouard  9806:        
                   9807:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9808:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9809:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9810:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9811:   }
                   9812:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9813:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9814:   
                   9815:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9816:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9817:   
1.218     brouard  9818:   /* agelim=AGESUP; */
                   9819:   ageminl=30;
                   9820:   hstepm=stepsize*YEARM; /* Every year of age */
                   9821:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9822:   
                   9823:   /* hstepm=1;   aff par mois*/
                   9824:   pstamp(ficrespijb);
1.255     brouard  9825:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9826:   i1= pow(2,cptcoveff);
1.218     brouard  9827:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9828:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9829:   /*   k=k+1;  */
1.238     brouard  9830:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9831:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9832:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9833:        continue;
                   9834:       fprintf(ficrespijb,"\n#****** ");
                   9835:       for(j=1;j<=cptcoveff;j++)
                   9836:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9837:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9838:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9839:       }
                   9840:       fprintf(ficrespijb,"******\n");
1.264   ! brouard  9841:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  9842:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9843:        continue;
                   9844:       }
                   9845:       
                   9846:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9847:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9848:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9849:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9850:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9851:        
                   9852:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9853:        
                   9854:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9855:        /* oldm=oldms;savm=savms; */
                   9856:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9857:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9858:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9859:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9860:        for(i=1; i<=nlstate;i++)
                   9861:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9862:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9863:        fprintf(ficrespijb,"\n");
1.238     brouard  9864:        for (h=0; h<=nhstepm; h++){
                   9865:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9866:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9867:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9868:          for(i=1; i<=nlstate;i++)
                   9869:            for(j=1; j<=nlstate+ndeath;j++)
                   9870:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9871:          fprintf(ficrespijb,"\n");
                   9872:        }
                   9873:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9874:        fprintf(ficrespijb,"\n");
                   9875:       } /* end age deb */
                   9876:     } /* end combination */
                   9877:   } /* end nres */
1.218     brouard  9878:   return 0;
                   9879:  } /*  hBijx */
1.217     brouard  9880: 
1.180     brouard  9881: 
1.136     brouard  9882: /***********************************************/
                   9883: /**************** Main Program *****************/
                   9884: /***********************************************/
                   9885: 
                   9886: int main(int argc, char *argv[])
                   9887: {
                   9888: #ifdef GSL
                   9889:   const gsl_multimin_fminimizer_type *T;
                   9890:   size_t iteri = 0, it;
                   9891:   int rval = GSL_CONTINUE;
                   9892:   int status = GSL_SUCCESS;
                   9893:   double ssval;
                   9894: #endif
                   9895:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9896:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9897:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9898:   int jj, ll, li, lj, lk;
1.136     brouard  9899:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9900:   int num_filled;
1.136     brouard  9901:   int itimes;
                   9902:   int NDIM=2;
                   9903:   int vpopbased=0;
1.235     brouard  9904:   int nres=0;
1.258     brouard  9905:   int endishere=0;
1.136     brouard  9906: 
1.164     brouard  9907:   char ca[32], cb[32];
1.136     brouard  9908:   /*  FILE *fichtm; *//* Html File */
                   9909:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9910:   struct stat info;
1.191     brouard  9911:   double agedeb=0.;
1.194     brouard  9912: 
                   9913:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9914:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9915: 
1.165     brouard  9916:   double fret;
1.191     brouard  9917:   double dum=0.; /* Dummy variable */
1.136     brouard  9918:   double ***p3mat;
1.218     brouard  9919:   /* double ***mobaverage; */
1.164     brouard  9920: 
                   9921:   char line[MAXLINE];
1.197     brouard  9922:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9923: 
1.234     brouard  9924:   char  modeltemp[MAXLINE];
1.230     brouard  9925:   char resultline[MAXLINE];
                   9926:   
1.136     brouard  9927:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9928:   char *tok, *val; /* pathtot */
1.136     brouard  9929:   int firstobs=1, lastobs=10;
1.195     brouard  9930:   int c,  h , cpt, c2;
1.191     brouard  9931:   int jl=0;
                   9932:   int i1, j1, jk, stepsize=0;
1.194     brouard  9933:   int count=0;
                   9934: 
1.164     brouard  9935:   int *tab; 
1.136     brouard  9936:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9937:   int backcast=0;
1.136     brouard  9938:   int mobilav=0,popforecast=0;
1.191     brouard  9939:   int hstepm=0, nhstepm=0;
1.136     brouard  9940:   int agemortsup;
                   9941:   float  sumlpop=0.;
                   9942:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9943:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9944: 
1.191     brouard  9945:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9946:   double ftolpl=FTOL;
                   9947:   double **prlim;
1.217     brouard  9948:   double **bprlim;
1.136     brouard  9949:   double ***param; /* Matrix of parameters */
1.251     brouard  9950:   double ***paramstart; /* Matrix of starting parameter values */
                   9951:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9952:   double **matcov; /* Matrix of covariance */
1.203     brouard  9953:   double **hess; /* Hessian matrix */
1.136     brouard  9954:   double ***delti3; /* Scale */
                   9955:   double *delti; /* Scale */
                   9956:   double ***eij, ***vareij;
                   9957:   double **varpl; /* Variances of prevalence limits by age */
                   9958:   double *epj, vepp;
1.164     brouard  9959: 
1.136     brouard  9960:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9961:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9962: 
1.136     brouard  9963:   double **ximort;
1.145     brouard  9964:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9965:   int *dcwave;
                   9966: 
1.164     brouard  9967:   char z[1]="c";
1.136     brouard  9968: 
                   9969:   /*char  *strt;*/
                   9970:   char strtend[80];
1.126     brouard  9971: 
1.164     brouard  9972: 
1.126     brouard  9973: /*   setlocale (LC_ALL, ""); */
                   9974: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9975: /*   textdomain (PACKAGE); */
                   9976: /*   setlocale (LC_CTYPE, ""); */
                   9977: /*   setlocale (LC_MESSAGES, ""); */
                   9978: 
                   9979:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9980:   rstart_time = time(NULL);  
                   9981:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9982:   start_time = *localtime(&rstart_time);
1.126     brouard  9983:   curr_time=start_time;
1.157     brouard  9984:   /*tml = *localtime(&start_time.tm_sec);*/
                   9985:   /* strcpy(strstart,asctime(&tml)); */
                   9986:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9987: 
                   9988: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9989: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9990: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9991: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9992: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9993: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9994: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9995: /*   strt=asctime(&tmg); */
                   9996: /*   printf("Time(after) =%s",strstart);  */
                   9997: /*  (void) time (&time_value);
                   9998: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9999: *  tm = *localtime(&time_value);
                   10000: *  strstart=asctime(&tm);
                   10001: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10002: */
                   10003: 
                   10004:   nberr=0; /* Number of errors and warnings */
                   10005:   nbwarn=0;
1.184     brouard  10006: #ifdef WIN32
                   10007:   _getcwd(pathcd, size);
                   10008: #else
1.126     brouard  10009:   getcwd(pathcd, size);
1.184     brouard  10010: #endif
1.191     brouard  10011:   syscompilerinfo(0);
1.196     brouard  10012:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10013:   if(argc <=1){
                   10014:     printf("\nEnter the parameter file name: ");
1.205     brouard  10015:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10016:       printf("ERROR Empty parameter file name\n");
                   10017:       goto end;
                   10018:     }
1.126     brouard  10019:     i=strlen(pathr);
                   10020:     if(pathr[i-1]=='\n')
                   10021:       pathr[i-1]='\0';
1.156     brouard  10022:     i=strlen(pathr);
1.205     brouard  10023:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10024:       pathr[i-1]='\0';
1.205     brouard  10025:     }
                   10026:     i=strlen(pathr);
                   10027:     if( i==0 ){
                   10028:       printf("ERROR Empty parameter file name\n");
                   10029:       goto end;
                   10030:     }
                   10031:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10032:       printf("Pathr |%s|\n",pathr);
                   10033:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10034:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10035:       strcpy (pathtot, val);
                   10036:       if(pathr[0] == '\0') break; /* Dirty */
                   10037:     }
                   10038:   }
                   10039:   else{
                   10040:     strcpy(pathtot,argv[1]);
                   10041:   }
                   10042:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10043:   /*cygwin_split_path(pathtot,path,optionfile);
                   10044:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10045:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10046: 
                   10047:   /* Split argv[0], imach program to get pathimach */
                   10048:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10049:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10050:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10051:  /*   strcpy(pathimach,argv[0]); */
                   10052:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10053:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10054:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10055: #ifdef WIN32
                   10056:   _chdir(path); /* Can be a relative path */
                   10057:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10058: #else
1.126     brouard  10059:   chdir(path); /* Can be a relative path */
1.184     brouard  10060:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10061: #endif
                   10062:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10063:   strcpy(command,"mkdir ");
                   10064:   strcat(command,optionfilefiname);
                   10065:   if((outcmd=system(command)) != 0){
1.169     brouard  10066:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10067:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10068:     /* fclose(ficlog); */
                   10069: /*     exit(1); */
                   10070:   }
                   10071: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10072: /*     perror("mkdir"); */
                   10073: /*   } */
                   10074: 
                   10075:   /*-------- arguments in the command line --------*/
                   10076: 
1.186     brouard  10077:   /* Main Log file */
1.126     brouard  10078:   strcat(filelog, optionfilefiname);
                   10079:   strcat(filelog,".log");    /* */
                   10080:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10081:     printf("Problem with logfile %s\n",filelog);
                   10082:     goto end;
                   10083:   }
                   10084:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10085:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10086:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10087:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10088:  path=%s \n\
                   10089:  optionfile=%s\n\
                   10090:  optionfilext=%s\n\
1.156     brouard  10091:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10092: 
1.197     brouard  10093:   syscompilerinfo(1);
1.167     brouard  10094: 
1.126     brouard  10095:   printf("Local time (at start):%s",strstart);
                   10096:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10097:   fflush(ficlog);
                   10098: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10099: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10100: 
                   10101:   /* */
                   10102:   strcpy(fileres,"r");
                   10103:   strcat(fileres, optionfilefiname);
1.201     brouard  10104:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10105:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10106:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10107: 
1.186     brouard  10108:   /* Main ---------arguments file --------*/
1.126     brouard  10109: 
                   10110:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10111:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10112:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10113:     fflush(ficlog);
1.149     brouard  10114:     /* goto end; */
                   10115:     exit(70); 
1.126     brouard  10116:   }
                   10117: 
                   10118: 
                   10119: 
                   10120:   strcpy(filereso,"o");
1.201     brouard  10121:   strcat(filereso,fileresu);
1.126     brouard  10122:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10123:     printf("Problem with Output resultfile: %s\n", filereso);
                   10124:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10125:     fflush(ficlog);
                   10126:     goto end;
                   10127:   }
                   10128: 
                   10129:   /* Reads comments: lines beginning with '#' */
                   10130:   numlinepar=0;
1.197     brouard  10131: 
                   10132:     /* First parameter line */
                   10133:   while(fgets(line, MAXLINE, ficpar)) {
                   10134:     /* If line starts with a # it is a comment */
                   10135:     if (line[0] == '#') {
                   10136:       numlinepar++;
                   10137:       fputs(line,stdout);
                   10138:       fputs(line,ficparo);
                   10139:       fputs(line,ficlog);
                   10140:       continue;
                   10141:     }else
                   10142:       break;
                   10143:   }
                   10144:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10145:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10146:     if (num_filled != 5) {
                   10147:       printf("Should be 5 parameters\n");
                   10148:     }
1.126     brouard  10149:     numlinepar++;
1.197     brouard  10150:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10151:   }
                   10152:   /* Second parameter line */
                   10153:   while(fgets(line, MAXLINE, ficpar)) {
                   10154:     /* If line starts with a # it is a comment */
                   10155:     if (line[0] == '#') {
                   10156:       numlinepar++;
                   10157:       fputs(line,stdout);
                   10158:       fputs(line,ficparo);
                   10159:       fputs(line,ficlog);
                   10160:       continue;
                   10161:     }else
                   10162:       break;
                   10163:   }
1.223     brouard  10164:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10165:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10166:     if (num_filled != 11) {
                   10167:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10168:       printf("but line=%s\n",line);
1.197     brouard  10169:     }
1.223     brouard  10170:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10171:   }
1.203     brouard  10172:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10173:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10174:   /* Third parameter line */
                   10175:   while(fgets(line, MAXLINE, ficpar)) {
                   10176:     /* If line starts with a # it is a comment */
                   10177:     if (line[0] == '#') {
                   10178:       numlinepar++;
                   10179:       fputs(line,stdout);
                   10180:       fputs(line,ficparo);
                   10181:       fputs(line,ficlog);
                   10182:       continue;
                   10183:     }else
                   10184:       break;
                   10185:   }
1.201     brouard  10186:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10187:     if (num_filled == 0){
                   10188:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10189:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10190:       model[0]='\0';
                   10191:       goto end;
                   10192:     } else if (num_filled != 1){
1.197     brouard  10193:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10194:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10195:       model[0]='\0';
                   10196:       goto end;
                   10197:     }
                   10198:     else{
                   10199:       if (model[0]=='+'){
                   10200:        for(i=1; i<=strlen(model);i++)
                   10201:          modeltemp[i-1]=model[i];
1.201     brouard  10202:        strcpy(model,modeltemp); 
1.197     brouard  10203:       }
                   10204:     }
1.199     brouard  10205:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10206:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10207:   }
                   10208:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10209:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10210:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10211:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10212:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10213:   fflush(ficlog);
1.190     brouard  10214:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10215:   if(model[0]=='#'){
1.187     brouard  10216:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10217:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10218:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10219:     if(mle != -1){
                   10220:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10221:       exit(1);
                   10222:     }
                   10223:   }
1.126     brouard  10224:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10225:     ungetc(c,ficpar);
                   10226:     fgets(line, MAXLINE, ficpar);
                   10227:     numlinepar++;
1.195     brouard  10228:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10229:       z[0]=line[1];
                   10230:     }
                   10231:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10232:     fputs(line, stdout);
                   10233:     //puts(line);
1.126     brouard  10234:     fputs(line,ficparo);
                   10235:     fputs(line,ficlog);
                   10236:   }
                   10237:   ungetc(c,ficpar);
                   10238: 
                   10239:    
1.145     brouard  10240:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10241:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10242:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10243:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10244:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10245:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10246:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10247:   */
                   10248:   if (strlen(model)>1) 
1.187     brouard  10249:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10250:   else
1.187     brouard  10251:     ncovmodel=2; /* Constant and age */
1.133     brouard  10252:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10253:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10254:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10255:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10256:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10257:     fflush(stdout);
                   10258:     fclose (ficlog);
                   10259:     goto end;
                   10260:   }
1.126     brouard  10261:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10262:   delti=delti3[1][1];
                   10263:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10264:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10265: /* We could also provide initial parameters values giving by simple logistic regression 
                   10266:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10267:       /* for(i=1;i<nlstate;i++){ */
                   10268:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10269:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10270:       /* } */
1.126     brouard  10271:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10272:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10273:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10274:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10275:     fclose (ficparo);
                   10276:     fclose (ficlog);
                   10277:     goto end;
                   10278:     exit(0);
1.220     brouard  10279:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10280:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10281:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10282:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10283:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10284:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10285:     hess=matrix(1,npar,1,npar);
1.220     brouard  10286:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10287:     /* Read guessed parameters */
1.126     brouard  10288:     /* Reads comments: lines beginning with '#' */
                   10289:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10290:       ungetc(c,ficpar);
                   10291:       fgets(line, MAXLINE, ficpar);
                   10292:       numlinepar++;
1.141     brouard  10293:       fputs(line,stdout);
1.126     brouard  10294:       fputs(line,ficparo);
                   10295:       fputs(line,ficlog);
                   10296:     }
                   10297:     ungetc(c,ficpar);
                   10298:     
                   10299:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10300:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10301:     for(i=1; i <=nlstate; i++){
1.234     brouard  10302:       j=0;
1.126     brouard  10303:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10304:        if(jj==i) continue;
                   10305:        j++;
                   10306:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10307:        if ((i1 != i) || (j1 != jj)){
                   10308:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10309: It might be a problem of design; if ncovcol and the model are correct\n \
                   10310: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10311:          exit(1);
                   10312:        }
                   10313:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10314:        if(mle==1)
                   10315:          printf("%1d%1d",i,jj);
                   10316:        fprintf(ficlog,"%1d%1d",i,jj);
                   10317:        for(k=1; k<=ncovmodel;k++){
                   10318:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10319:          if(mle==1){
                   10320:            printf(" %lf",param[i][j][k]);
                   10321:            fprintf(ficlog," %lf",param[i][j][k]);
                   10322:          }
                   10323:          else
                   10324:            fprintf(ficlog," %lf",param[i][j][k]);
                   10325:          fprintf(ficparo," %lf",param[i][j][k]);
                   10326:        }
                   10327:        fscanf(ficpar,"\n");
                   10328:        numlinepar++;
                   10329:        if(mle==1)
                   10330:          printf("\n");
                   10331:        fprintf(ficlog,"\n");
                   10332:        fprintf(ficparo,"\n");
1.126     brouard  10333:       }
                   10334:     }  
                   10335:     fflush(ficlog);
1.234     brouard  10336:     
1.251     brouard  10337:     /* Reads parameters values */
1.126     brouard  10338:     p=param[1][1];
1.251     brouard  10339:     pstart=paramstart[1][1];
1.126     brouard  10340:     
                   10341:     /* Reads comments: lines beginning with '#' */
                   10342:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10343:       ungetc(c,ficpar);
                   10344:       fgets(line, MAXLINE, ficpar);
                   10345:       numlinepar++;
1.141     brouard  10346:       fputs(line,stdout);
1.126     brouard  10347:       fputs(line,ficparo);
                   10348:       fputs(line,ficlog);
                   10349:     }
                   10350:     ungetc(c,ficpar);
                   10351: 
                   10352:     for(i=1; i <=nlstate; i++){
                   10353:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10354:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10355:        if ( (i1-i) * (j1-j) != 0){
                   10356:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10357:          exit(1);
                   10358:        }
                   10359:        printf("%1d%1d",i,j);
                   10360:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10361:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10362:        for(k=1; k<=ncovmodel;k++){
                   10363:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10364:          printf(" %le",delti3[i][j][k]);
                   10365:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10366:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10367:        }
                   10368:        fscanf(ficpar,"\n");
                   10369:        numlinepar++;
                   10370:        printf("\n");
                   10371:        fprintf(ficparo,"\n");
                   10372:        fprintf(ficlog,"\n");
1.126     brouard  10373:       }
                   10374:     }
                   10375:     fflush(ficlog);
1.234     brouard  10376:     
1.145     brouard  10377:     /* Reads covariance matrix */
1.126     brouard  10378:     delti=delti3[1][1];
1.220     brouard  10379:                
                   10380:                
1.126     brouard  10381:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10382:                
1.126     brouard  10383:     /* Reads comments: lines beginning with '#' */
                   10384:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10385:       ungetc(c,ficpar);
                   10386:       fgets(line, MAXLINE, ficpar);
                   10387:       numlinepar++;
1.141     brouard  10388:       fputs(line,stdout);
1.126     brouard  10389:       fputs(line,ficparo);
                   10390:       fputs(line,ficlog);
                   10391:     }
                   10392:     ungetc(c,ficpar);
1.220     brouard  10393:                
1.126     brouard  10394:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10395:     hess=matrix(1,npar,1,npar);
1.131     brouard  10396:     for(i=1; i <=npar; i++)
                   10397:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10398:                
1.194     brouard  10399:     /* Scans npar lines */
1.126     brouard  10400:     for(i=1; i <=npar; i++){
1.226     brouard  10401:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10402:       if(count != 3){
1.226     brouard  10403:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10404: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10405: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10406:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10407: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10408: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10409:        exit(1);
1.220     brouard  10410:       }else{
1.226     brouard  10411:        if(mle==1)
                   10412:          printf("%1d%1d%d",i1,j1,jk);
                   10413:       }
                   10414:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10415:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10416:       for(j=1; j <=i; j++){
1.226     brouard  10417:        fscanf(ficpar," %le",&matcov[i][j]);
                   10418:        if(mle==1){
                   10419:          printf(" %.5le",matcov[i][j]);
                   10420:        }
                   10421:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10422:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10423:       }
                   10424:       fscanf(ficpar,"\n");
                   10425:       numlinepar++;
                   10426:       if(mle==1)
1.220     brouard  10427:                                printf("\n");
1.126     brouard  10428:       fprintf(ficlog,"\n");
                   10429:       fprintf(ficparo,"\n");
                   10430:     }
1.194     brouard  10431:     /* End of read covariance matrix npar lines */
1.126     brouard  10432:     for(i=1; i <=npar; i++)
                   10433:       for(j=i+1;j<=npar;j++)
1.226     brouard  10434:        matcov[i][j]=matcov[j][i];
1.126     brouard  10435:     
                   10436:     if(mle==1)
                   10437:       printf("\n");
                   10438:     fprintf(ficlog,"\n");
                   10439:     
                   10440:     fflush(ficlog);
                   10441:     
                   10442:     /*-------- Rewriting parameter file ----------*/
                   10443:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10444:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10445:     strcat(rfileres,".");    /* */
                   10446:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10447:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10448:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10449:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10450:     }
                   10451:     fprintf(ficres,"#%s\n",version);
                   10452:   }    /* End of mle != -3 */
1.218     brouard  10453:   
1.186     brouard  10454:   /*  Main data
                   10455:    */
1.126     brouard  10456:   n= lastobs;
                   10457:   num=lvector(1,n);
                   10458:   moisnais=vector(1,n);
                   10459:   annais=vector(1,n);
                   10460:   moisdc=vector(1,n);
                   10461:   andc=vector(1,n);
1.220     brouard  10462:   weight=vector(1,n);
1.126     brouard  10463:   agedc=vector(1,n);
                   10464:   cod=ivector(1,n);
1.220     brouard  10465:   for(i=1;i<=n;i++){
1.234     brouard  10466:     num[i]=0;
                   10467:     moisnais[i]=0;
                   10468:     annais[i]=0;
                   10469:     moisdc[i]=0;
                   10470:     andc[i]=0;
                   10471:     agedc[i]=0;
                   10472:     cod[i]=0;
                   10473:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10474:   }
1.126     brouard  10475:   mint=matrix(1,maxwav,1,n);
                   10476:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10477:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10478:   tab=ivector(1,NCOVMAX);
1.144     brouard  10479:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10480:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10481: 
1.136     brouard  10482:   /* Reads data from file datafile */
                   10483:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10484:     goto end;
                   10485: 
                   10486:   /* Calculation of the number of parameters from char model */
1.234     brouard  10487:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10488:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10489:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10490:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10491:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10492:   */
                   10493:   
                   10494:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10495:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10496:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10497:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10498:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10499:   TvarF=ivector(1,NCOVMAX); /*  */
                   10500:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10501:   TvarV=ivector(1,NCOVMAX); /*  */
                   10502:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10503:   TvarA=ivector(1,NCOVMAX); /*  */
                   10504:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10505:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10506:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10507:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10508:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10509:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10510:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10511:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10512:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10513: 
1.230     brouard  10514:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10515:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10516:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10517:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10518:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10519:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10520:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10521:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10522:   */
                   10523:   /* For model-covariate k tells which data-covariate to use but
                   10524:     because this model-covariate is a construction we invent a new column
                   10525:     ncovcol + k1
                   10526:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10527:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10528:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10529:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10530:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10531:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10532:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10533:   */
1.145     brouard  10534:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10535:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10536:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10537:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10538:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10539:                         4 covariates (3 plus signs)
                   10540:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10541:                      */  
1.230     brouard  10542:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10543:                                * individual dummy, fixed or varying:
                   10544:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10545:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10546:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10547:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10548:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10549:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10550:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10551:                                * individual quantitative, fixed or varying:
                   10552:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10553:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10554:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10555: /* Main decodemodel */
                   10556: 
1.187     brouard  10557: 
1.223     brouard  10558:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10559:     goto end;
                   10560: 
1.137     brouard  10561:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10562:     nbwarn++;
                   10563:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10564:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10565:   }
1.136     brouard  10566:     /*  if(mle==1){*/
1.137     brouard  10567:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10568:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10569:   }
                   10570: 
                   10571:     /*-calculation of age at interview from date of interview and age at death -*/
                   10572:   agev=matrix(1,maxwav,1,imx);
                   10573: 
                   10574:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10575:     goto end;
                   10576: 
1.126     brouard  10577: 
1.136     brouard  10578:   agegomp=(int)agemin;
                   10579:   free_vector(moisnais,1,n);
                   10580:   free_vector(annais,1,n);
1.126     brouard  10581:   /* free_matrix(mint,1,maxwav,1,n);
                   10582:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10583:   /* free_vector(moisdc,1,n); */
                   10584:   /* free_vector(andc,1,n); */
1.145     brouard  10585:   /* */
                   10586:   
1.126     brouard  10587:   wav=ivector(1,imx);
1.214     brouard  10588:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10589:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10590:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10591:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10592:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10593:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10594:    
                   10595:   /* Concatenates waves */
1.214     brouard  10596:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10597:      Death is a valid wave (if date is known).
                   10598:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10599:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10600:      and mw[mi+1][i]. dh depends on stepm.
                   10601:   */
                   10602: 
1.126     brouard  10603:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10604:   /* Concatenates waves */
1.145     brouard  10605:  
1.215     brouard  10606:   free_vector(moisdc,1,n);
                   10607:   free_vector(andc,1,n);
                   10608: 
1.126     brouard  10609:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10610:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10611:   ncodemax[1]=1;
1.145     brouard  10612:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10613:   cptcoveff=0;
1.220     brouard  10614:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10615:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10616:   }
                   10617:   
                   10618:   ncovcombmax=pow(2,cptcoveff);
                   10619:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10620:   for(i=1;i<ncovcombmax;i++)
                   10621:     invalidvarcomb[i]=0;
                   10622:   
1.211     brouard  10623:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10624:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10625:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10626:   
1.200     brouard  10627:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10628:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10629:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10630:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10631:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10632:    * (currently 0 or 1) in the data.
                   10633:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10634:    * corresponding modality (h,j).
                   10635:    */
                   10636: 
1.145     brouard  10637:   h=0;
                   10638:   /*if (cptcovn > 0) */
1.126     brouard  10639:   m=pow(2,cptcoveff);
                   10640:  
1.144     brouard  10641:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10642:           * For k=4 covariates, h goes from 1 to m=2**k
                   10643:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10644:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10645:           *     h\k   1     2     3     4
1.143     brouard  10646:           *______________________________  
                   10647:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10648:           *     2     2     1     1     1
                   10649:           *     3 i=2 1     2     1     1
                   10650:           *     4     2     2     1     1
                   10651:           *     5 i=3 1 i=2 1     2     1
                   10652:           *     6     2     1     2     1
                   10653:           *     7 i=4 1     2     2     1
                   10654:           *     8     2     2     2     1
1.197     brouard  10655:           *     9 i=5 1 i=3 1 i=2 1     2
                   10656:           *    10     2     1     1     2
                   10657:           *    11 i=6 1     2     1     2
                   10658:           *    12     2     2     1     2
                   10659:           *    13 i=7 1 i=4 1     2     2    
                   10660:           *    14     2     1     2     2
                   10661:           *    15 i=8 1     2     2     2
                   10662:           *    16     2     2     2     2
1.143     brouard  10663:           */
1.212     brouard  10664:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10665:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10666:      * and the value of each covariate?
                   10667:      * V1=1, V2=1, V3=2, V4=1 ?
                   10668:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10669:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10670:      * In order to get the real value in the data, we use nbcode
                   10671:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10672:      * We are keeping this crazy system in order to be able (in the future?) 
                   10673:      * to have more than 2 values (0 or 1) for a covariate.
                   10674:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10675:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10676:      *              bbbbbbbb
                   10677:      *              76543210     
                   10678:      *   h-1        00000101 (6-1=5)
1.219     brouard  10679:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10680:      *           &
                   10681:      *     1        00000001 (1)
1.219     brouard  10682:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10683:      *          +1= 00000001 =1 
1.211     brouard  10684:      *
                   10685:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10686:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10687:      *    >>k'            11
                   10688:      *          &   00000001
                   10689:      *            = 00000001
                   10690:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10691:      * Reverse h=6 and m=16?
                   10692:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10693:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10694:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10695:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10696:      * V3=decodtabm(14,3,2**4)=2
                   10697:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10698:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10699:      *          &1 000000001
                   10700:      *           = 000000001
                   10701:      *         +1= 000000010 =2
                   10702:      *                  2211
                   10703:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10704:      *                  V3=2
1.220     brouard  10705:                 * codtabm and decodtabm are identical
1.211     brouard  10706:      */
                   10707: 
1.145     brouard  10708: 
                   10709:  free_ivector(Ndum,-1,NCOVMAX);
                   10710: 
                   10711: 
1.126     brouard  10712:     
1.186     brouard  10713:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10714:   strcpy(optionfilegnuplot,optionfilefiname);
                   10715:   if(mle==-3)
1.201     brouard  10716:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10717:   strcat(optionfilegnuplot,".gp");
                   10718: 
                   10719:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10720:     printf("Problem with file %s",optionfilegnuplot);
                   10721:   }
                   10722:   else{
1.204     brouard  10723:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10724:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10725:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10726:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10727:   }
                   10728:   /*  fclose(ficgp);*/
1.186     brouard  10729: 
                   10730: 
                   10731:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10732: 
                   10733:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10734:   if(mle==-3)
1.201     brouard  10735:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10736:   strcat(optionfilehtm,".htm");
                   10737:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10738:     printf("Problem with %s \n",optionfilehtm);
                   10739:     exit(0);
1.126     brouard  10740:   }
                   10741: 
                   10742:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10743:   strcat(optionfilehtmcov,"-cov.htm");
                   10744:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10745:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10746:   }
                   10747:   else{
                   10748:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10749: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10750: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10751:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10752:   }
                   10753: 
1.213     brouard  10754:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10755: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10756: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10757: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10758: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10759: \n\
                   10760: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10761:  <ul><li><h4>Parameter files</h4>\n\
                   10762:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10763:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10764:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10765:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10766:  - Date and time at start: %s</ul>\n",\
                   10767:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10768:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10769:          fileres,fileres,\
                   10770:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10771:   fflush(fichtm);
                   10772: 
                   10773:   strcpy(pathr,path);
                   10774:   strcat(pathr,optionfilefiname);
1.184     brouard  10775: #ifdef WIN32
                   10776:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10777: #else
1.126     brouard  10778:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10779: #endif
                   10780:          
1.126     brouard  10781:   
1.220     brouard  10782:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10783:                 and for any valid combination of covariates
1.126     brouard  10784:      and prints on file fileres'p'. */
1.251     brouard  10785:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10786:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10787: 
                   10788:   fprintf(fichtm,"\n");
                   10789:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10790: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10791: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10792:          imx,agemin,agemax,jmin,jmax,jmean);
                   10793:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10794:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10795:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10796:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10797:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10798: 
1.126     brouard  10799:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10800:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10801:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10802: 
                   10803:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10804:   /* For mortality only */
1.126     brouard  10805:   if (mle==-3){
1.136     brouard  10806:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10807:     for(i=1;i<=NDIM;i++)
                   10808:       for(j=1;j<=NDIM;j++)
                   10809:        ximort[i][j]=0.;
1.186     brouard  10810:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10811:     cens=ivector(1,n);
                   10812:     ageexmed=vector(1,n);
                   10813:     agecens=vector(1,n);
                   10814:     dcwave=ivector(1,n);
1.223     brouard  10815:                
1.126     brouard  10816:     for (i=1; i<=imx; i++){
                   10817:       dcwave[i]=-1;
                   10818:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10819:        if (s[m][i]>nlstate) {
                   10820:          dcwave[i]=m;
                   10821:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10822:          break;
                   10823:        }
1.126     brouard  10824:     }
1.226     brouard  10825:     
1.126     brouard  10826:     for (i=1; i<=imx; i++) {
                   10827:       if (wav[i]>0){
1.226     brouard  10828:        ageexmed[i]=agev[mw[1][i]][i];
                   10829:        j=wav[i];
                   10830:        agecens[i]=1.; 
                   10831:        
                   10832:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10833:          agecens[i]=agev[mw[j][i]][i];
                   10834:          cens[i]= 1;
                   10835:        }else if (ageexmed[i]< 1) 
                   10836:          cens[i]= -1;
                   10837:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10838:          cens[i]=0 ;
1.126     brouard  10839:       }
                   10840:       else cens[i]=-1;
                   10841:     }
                   10842:     
                   10843:     for (i=1;i<=NDIM;i++) {
                   10844:       for (j=1;j<=NDIM;j++)
1.226     brouard  10845:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10846:     }
                   10847:     
1.145     brouard  10848:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10849:     /*printf("%lf %lf", p[1], p[2]);*/
                   10850:     
                   10851:     
1.136     brouard  10852: #ifdef GSL
                   10853:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10854: #else
1.126     brouard  10855:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10856: #endif
1.201     brouard  10857:     strcpy(filerespow,"POW-MORT_"); 
                   10858:     strcat(filerespow,fileresu);
1.126     brouard  10859:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10860:       printf("Problem with resultfile: %s\n", filerespow);
                   10861:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10862:     }
1.136     brouard  10863: #ifdef GSL
                   10864:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10865: #else
1.126     brouard  10866:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10867: #endif
1.126     brouard  10868:     /*  for (i=1;i<=nlstate;i++)
                   10869:        for(j=1;j<=nlstate+ndeath;j++)
                   10870:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10871:     */
                   10872:     fprintf(ficrespow,"\n");
1.136     brouard  10873: #ifdef GSL
                   10874:     /* gsl starts here */ 
                   10875:     T = gsl_multimin_fminimizer_nmsimplex;
                   10876:     gsl_multimin_fminimizer *sfm = NULL;
                   10877:     gsl_vector *ss, *x;
                   10878:     gsl_multimin_function minex_func;
                   10879: 
                   10880:     /* Initial vertex size vector */
                   10881:     ss = gsl_vector_alloc (NDIM);
                   10882:     
                   10883:     if (ss == NULL){
                   10884:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10885:     }
                   10886:     /* Set all step sizes to 1 */
                   10887:     gsl_vector_set_all (ss, 0.001);
                   10888: 
                   10889:     /* Starting point */
1.126     brouard  10890:     
1.136     brouard  10891:     x = gsl_vector_alloc (NDIM);
                   10892:     
                   10893:     if (x == NULL){
                   10894:       gsl_vector_free(ss);
                   10895:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10896:     }
                   10897:   
                   10898:     /* Initialize method and iterate */
                   10899:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10900:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10901:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10902:     gsl_vector_set(x, 0, p[1]);
                   10903:     gsl_vector_set(x, 1, p[2]);
                   10904: 
                   10905:     minex_func.f = &gompertz_f;
                   10906:     minex_func.n = NDIM;
                   10907:     minex_func.params = (void *)&p; /* ??? */
                   10908:     
                   10909:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10910:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10911:     
                   10912:     printf("Iterations beginning .....\n\n");
                   10913:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10914: 
                   10915:     iteri=0;
                   10916:     while (rval == GSL_CONTINUE){
                   10917:       iteri++;
                   10918:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10919:       
                   10920:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10921:       fflush(0);
                   10922:       
                   10923:       if (status) 
                   10924:         break;
                   10925:       
                   10926:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10927:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10928:       
                   10929:       if (rval == GSL_SUCCESS)
                   10930:         printf ("converged to a local maximum at\n");
                   10931:       
                   10932:       printf("%5d ", iteri);
                   10933:       for (it = 0; it < NDIM; it++){
                   10934:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10935:       }
                   10936:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10937:     }
                   10938:     
                   10939:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10940:     
                   10941:     gsl_vector_free(x); /* initial values */
                   10942:     gsl_vector_free(ss); /* inital step size */
                   10943:     for (it=0; it<NDIM; it++){
                   10944:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10945:       fprintf(ficrespow," %.12lf", p[it]);
                   10946:     }
                   10947:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10948: #endif
                   10949: #ifdef POWELL
                   10950:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10951: #endif  
1.126     brouard  10952:     fclose(ficrespow);
                   10953:     
1.203     brouard  10954:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10955: 
                   10956:     for(i=1; i <=NDIM; i++)
                   10957:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10958:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10959:     
                   10960:     printf("\nCovariance matrix\n ");
1.203     brouard  10961:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10962:     for(i=1; i <=NDIM; i++) {
                   10963:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10964:                                printf("%f ",matcov[i][j]);
                   10965:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10966:       }
1.203     brouard  10967:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10968:     }
                   10969:     
                   10970:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10971:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10972:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10973:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10974:     }
1.126     brouard  10975:     lsurv=vector(1,AGESUP);
                   10976:     lpop=vector(1,AGESUP);
                   10977:     tpop=vector(1,AGESUP);
                   10978:     lsurv[agegomp]=100000;
                   10979:     
                   10980:     for (k=agegomp;k<=AGESUP;k++) {
                   10981:       agemortsup=k;
                   10982:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10983:     }
                   10984:     
                   10985:     for (k=agegomp;k<agemortsup;k++)
                   10986:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10987:     
                   10988:     for (k=agegomp;k<agemortsup;k++){
                   10989:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10990:       sumlpop=sumlpop+lpop[k];
                   10991:     }
                   10992:     
                   10993:     tpop[agegomp]=sumlpop;
                   10994:     for (k=agegomp;k<(agemortsup-3);k++){
                   10995:       /*  tpop[k+1]=2;*/
                   10996:       tpop[k+1]=tpop[k]-lpop[k];
                   10997:     }
                   10998:     
                   10999:     
                   11000:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11001:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11002:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11003:     
                   11004:     
                   11005:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11006:                ageminpar=50;
                   11007:                agemaxpar=100;
1.194     brouard  11008:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11009:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11010: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11011: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11012:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11013: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11014: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11015:     }else{
                   11016:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11017:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11018:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11019:                }
1.201     brouard  11020:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11021:                     stepm, weightopt,\
                   11022:                     model,imx,p,matcov,agemortsup);
                   11023:     
                   11024:     free_vector(lsurv,1,AGESUP);
                   11025:     free_vector(lpop,1,AGESUP);
                   11026:     free_vector(tpop,1,AGESUP);
1.220     brouard  11027:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11028:     free_ivector(cens,1,n);
                   11029:     free_vector(agecens,1,n);
                   11030:     free_ivector(dcwave,1,n);
1.220     brouard  11031: #ifdef GSL
1.136     brouard  11032: #endif
1.186     brouard  11033:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11034:   /* Standard  */
                   11035:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11036:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11037:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11038:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11039:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11040:     for (k=1; k<=npar;k++)
                   11041:       printf(" %d %8.5f",k,p[k]);
                   11042:     printf("\n");
1.205     brouard  11043:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11044:       /* mlikeli uses func not funcone */
1.247     brouard  11045:       /* for(i=1;i<nlstate;i++){ */
                   11046:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11047:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11048:       /* } */
1.205     brouard  11049:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11050:     }
                   11051:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11052:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11053:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11054:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11055:     }
                   11056:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11057:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11058:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11059:     for (k=1; k<=npar;k++)
                   11060:       printf(" %d %8.5f",k,p[k]);
                   11061:     printf("\n");
                   11062:     
                   11063:     /*--------- results files --------------*/
1.224     brouard  11064:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11065:     
                   11066:     
                   11067:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11068:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11069:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11070:     for(i=1,jk=1; i <=nlstate; i++){
                   11071:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11072:        if (k != i) {
                   11073:          printf("%d%d ",i,k);
                   11074:          fprintf(ficlog,"%d%d ",i,k);
                   11075:          fprintf(ficres,"%1d%1d ",i,k);
                   11076:          for(j=1; j <=ncovmodel; j++){
                   11077:            printf("%12.7f ",p[jk]);
                   11078:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11079:            fprintf(ficres,"%12.7f ",p[jk]);
                   11080:            jk++; 
                   11081:          }
                   11082:          printf("\n");
                   11083:          fprintf(ficlog,"\n");
                   11084:          fprintf(ficres,"\n");
                   11085:        }
1.126     brouard  11086:       }
                   11087:     }
1.203     brouard  11088:     if(mle != 0){
                   11089:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11090:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11091:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11092:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11093:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11094:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11095:        for(k=1; k <=(nlstate+ndeath); k++){
                   11096:          if (k != i) {
                   11097:            printf("%d%d ",i,k);
                   11098:            fprintf(ficlog,"%d%d ",i,k);
                   11099:            for(j=1; j <=ncovmodel; j++){
                   11100:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11101:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11102:              jk++; 
                   11103:            }
                   11104:            printf("\n");
                   11105:            fprintf(ficlog,"\n");
                   11106:          }
                   11107:        }
1.193     brouard  11108:       }
1.203     brouard  11109:     } /* end of hesscov and Wald tests */
1.225     brouard  11110:     
1.203     brouard  11111:     /*  */
1.126     brouard  11112:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11113:     printf("# Scales (for hessian or gradient estimation)\n");
                   11114:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11115:     for(i=1,jk=1; i <=nlstate; i++){
                   11116:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11117:        if (j!=i) {
                   11118:          fprintf(ficres,"%1d%1d",i,j);
                   11119:          printf("%1d%1d",i,j);
                   11120:          fprintf(ficlog,"%1d%1d",i,j);
                   11121:          for(k=1; k<=ncovmodel;k++){
                   11122:            printf(" %.5e",delti[jk]);
                   11123:            fprintf(ficlog," %.5e",delti[jk]);
                   11124:            fprintf(ficres," %.5e",delti[jk]);
                   11125:            jk++;
                   11126:          }
                   11127:          printf("\n");
                   11128:          fprintf(ficlog,"\n");
                   11129:          fprintf(ficres,"\n");
                   11130:        }
1.126     brouard  11131:       }
                   11132:     }
                   11133:     
                   11134:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11135:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11136:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11137:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11138:     /* # 121 Var(a12)\n\ */
                   11139:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11140:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11141:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11142:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11143:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11144:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11145:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11146:     
                   11147:     
                   11148:     /* Just to have a covariance matrix which will be more understandable
                   11149:        even is we still don't want to manage dictionary of variables
                   11150:     */
                   11151:     for(itimes=1;itimes<=2;itimes++){
                   11152:       jj=0;
                   11153:       for(i=1; i <=nlstate; i++){
1.225     brouard  11154:        for(j=1; j <=nlstate+ndeath; j++){
                   11155:          if(j==i) continue;
                   11156:          for(k=1; k<=ncovmodel;k++){
                   11157:            jj++;
                   11158:            ca[0]= k+'a'-1;ca[1]='\0';
                   11159:            if(itimes==1){
                   11160:              if(mle>=1)
                   11161:                printf("#%1d%1d%d",i,j,k);
                   11162:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11163:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11164:            }else{
                   11165:              if(mle>=1)
                   11166:                printf("%1d%1d%d",i,j,k);
                   11167:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11168:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11169:            }
                   11170:            ll=0;
                   11171:            for(li=1;li <=nlstate; li++){
                   11172:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11173:                if(lj==li) continue;
                   11174:                for(lk=1;lk<=ncovmodel;lk++){
                   11175:                  ll++;
                   11176:                  if(ll<=jj){
                   11177:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11178:                    if(ll<jj){
                   11179:                      if(itimes==1){
                   11180:                        if(mle>=1)
                   11181:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11182:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11183:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11184:                      }else{
                   11185:                        if(mle>=1)
                   11186:                          printf(" %.5e",matcov[jj][ll]); 
                   11187:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11188:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11189:                      }
                   11190:                    }else{
                   11191:                      if(itimes==1){
                   11192:                        if(mle>=1)
                   11193:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11194:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11195:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11196:                      }else{
                   11197:                        if(mle>=1)
                   11198:                          printf(" %.7e",matcov[jj][ll]); 
                   11199:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11200:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11201:                      }
                   11202:                    }
                   11203:                  }
                   11204:                } /* end lk */
                   11205:              } /* end lj */
                   11206:            } /* end li */
                   11207:            if(mle>=1)
                   11208:              printf("\n");
                   11209:            fprintf(ficlog,"\n");
                   11210:            fprintf(ficres,"\n");
                   11211:            numlinepar++;
                   11212:          } /* end k*/
                   11213:        } /*end j */
1.126     brouard  11214:       } /* end i */
                   11215:     } /* end itimes */
                   11216:     
                   11217:     fflush(ficlog);
                   11218:     fflush(ficres);
1.225     brouard  11219:     while(fgets(line, MAXLINE, ficpar)) {
                   11220:       /* If line starts with a # it is a comment */
                   11221:       if (line[0] == '#') {
                   11222:        numlinepar++;
                   11223:        fputs(line,stdout);
                   11224:        fputs(line,ficparo);
                   11225:        fputs(line,ficlog);
                   11226:        continue;
                   11227:       }else
                   11228:        break;
                   11229:     }
                   11230:     
1.209     brouard  11231:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11232:     /*   ungetc(c,ficpar); */
                   11233:     /*   fgets(line, MAXLINE, ficpar); */
                   11234:     /*   fputs(line,stdout); */
                   11235:     /*   fputs(line,ficparo); */
                   11236:     /* } */
                   11237:     /* ungetc(c,ficpar); */
1.126     brouard  11238:     
                   11239:     estepm=0;
1.209     brouard  11240:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11241:       
                   11242:       if (num_filled != 6) {
                   11243:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11244:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11245:        goto end;
                   11246:       }
                   11247:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11248:     }
                   11249:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11250:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11251:     
1.209     brouard  11252:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11253:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11254:     if (fage <= 2) {
                   11255:       bage = ageminpar;
                   11256:       fage = agemaxpar;
                   11257:     }
                   11258:     
                   11259:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11260:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11261:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11262:                
1.186     brouard  11263:     /* Other stuffs, more or less useful */    
1.254     brouard  11264:     while(fgets(line, MAXLINE, ficpar)) {
                   11265:       /* If line starts with a # it is a comment */
                   11266:       if (line[0] == '#') {
                   11267:        numlinepar++;
                   11268:        fputs(line,stdout);
                   11269:        fputs(line,ficparo);
                   11270:        fputs(line,ficlog);
                   11271:        continue;
                   11272:       }else
                   11273:        break;
                   11274:     }
                   11275: 
                   11276:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11277:       
                   11278:       if (num_filled != 7) {
                   11279:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11280:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11281:        goto end;
                   11282:       }
                   11283:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11284:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11285:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11286:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11287:     }
1.254     brouard  11288: 
                   11289:     while(fgets(line, MAXLINE, ficpar)) {
                   11290:       /* If line starts with a # it is a comment */
                   11291:       if (line[0] == '#') {
                   11292:        numlinepar++;
                   11293:        fputs(line,stdout);
                   11294:        fputs(line,ficparo);
                   11295:        fputs(line,ficlog);
                   11296:        continue;
                   11297:       }else
                   11298:        break;
1.126     brouard  11299:     }
                   11300:     
                   11301:     
                   11302:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11303:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11304:     
1.254     brouard  11305:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11306:       if (num_filled != 1) {
                   11307:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11308:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11309:        goto end;
                   11310:       }
                   11311:       printf("pop_based=%d\n",popbased);
                   11312:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11313:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11314:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11315:     }
                   11316:      
1.258     brouard  11317:     /* Results */
                   11318:     nresult=0;
                   11319:     do{
                   11320:       if(!fgets(line, MAXLINE, ficpar)){
                   11321:        endishere=1;
                   11322:        parameterline=14;
                   11323:       }else if (line[0] == '#') {
                   11324:        /* If line starts with a # it is a comment */
1.254     brouard  11325:        numlinepar++;
                   11326:        fputs(line,stdout);
                   11327:        fputs(line,ficparo);
                   11328:        fputs(line,ficlog);
                   11329:        continue;
1.258     brouard  11330:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11331:        parameterline=11;
                   11332:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11333:        parameterline=12;
                   11334:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11335:        parameterline=13;
                   11336:       else{
                   11337:        parameterline=14;
1.254     brouard  11338:       }
1.258     brouard  11339:       switch (parameterline){ 
                   11340:       case 11:
                   11341:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11342:          if (num_filled != 8) {
                   11343:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11344:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11345:            goto end;
                   11346:          }
                   11347:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11348:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11349:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11350:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11351:          /* day and month of proj2 are not used but only year anproj2.*/
                   11352:        }
1.254     brouard  11353:        break;
1.258     brouard  11354:       case 12:
                   11355:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11356:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11357:          if (num_filled != 8) {
1.262     brouard  11358:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11359:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  11360:            goto end;
                   11361:          }
                   11362:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11363:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11364:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11365:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11366:          /* day and month of proj2 are not used but only year anproj2.*/
                   11367:        }
1.230     brouard  11368:        break;
1.258     brouard  11369:       case 13:
                   11370:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11371:          if (num_filled == 0){
                   11372:            resultline[0]='\0';
                   11373:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11374:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11375:            break;
                   11376:          } else if (num_filled != 1){
                   11377:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11378:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11379:          }
                   11380:          nresult++; /* Sum of resultlines */
                   11381:          printf("Result %d: result=%s\n",nresult, resultline);
                   11382:          if(nresult > MAXRESULTLINES){
                   11383:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11384:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11385:            goto end;
                   11386:          }
                   11387:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11388:          fprintf(ficparo,"result: %s\n",resultline);
                   11389:          fprintf(ficres,"result: %s\n",resultline);
                   11390:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11391:          break;
1.258     brouard  11392:        case 14: 
1.259     brouard  11393:          if(ncovmodel >2 && nresult==0 ){
                   11394:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11395:            goto end;
                   11396:          }
1.259     brouard  11397:          break;
1.258     brouard  11398:        default:
                   11399:          nresult=1;
                   11400:          decoderesult(".",nresult ); /* No covariate */
                   11401:        }
                   11402:       } /* End switch parameterline */
                   11403:     }while(endishere==0); /* End do */
1.126     brouard  11404:     
1.230     brouard  11405:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11406:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11407:     
                   11408:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11409:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11410:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11411: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11412: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11413:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11414: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11415: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11416:     }else{
1.218     brouard  11417:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11418:     }
                   11419:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11420:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11421:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11422:                
1.225     brouard  11423:     /*------------ free_vector  -------------*/
                   11424:     /*  chdir(path); */
1.220     brouard  11425:                
1.215     brouard  11426:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11427:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11428:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11429:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11430:     free_lvector(num,1,n);
                   11431:     free_vector(agedc,1,n);
                   11432:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11433:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11434:     fclose(ficparo);
                   11435:     fclose(ficres);
1.220     brouard  11436:                
                   11437:                
1.186     brouard  11438:     /* Other results (useful)*/
1.220     brouard  11439:                
                   11440:                
1.126     brouard  11441:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11442:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11443:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11444:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11445:     fclose(ficrespl);
                   11446: 
                   11447:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11448:     /*#include "hpijx.h"*/
                   11449:     hPijx(p, bage, fage);
1.145     brouard  11450:     fclose(ficrespij);
1.227     brouard  11451:     
1.220     brouard  11452:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11453:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11454:     k=1;
1.126     brouard  11455:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11456:     
1.219     brouard  11457:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11458:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11459:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11460:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11461:        for(k=1;k<=ncovcombmax;k++)
                   11462:          probs[i][j][k]=0.;
1.219     brouard  11463:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11464:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11465:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11466:       for(i=1;i<=AGESUP;i++)
                   11467:        for(j=1;j<=nlstate;j++)
                   11468:          for(k=1;k<=ncovcombmax;k++)
                   11469:            mobaverages[i][j][k]=0.;
1.219     brouard  11470:       mobaverage=mobaverages;
                   11471:       if (mobilav!=0) {
1.235     brouard  11472:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11473:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11474:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11475:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11476:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11477:        }
1.219     brouard  11478:       }
                   11479:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11480:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11481:       else if (mobilavproj !=0) {
1.235     brouard  11482:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11483:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11484:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11485:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11486:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11487:        }
1.219     brouard  11488:       }
                   11489:     }/* end if moving average */
1.227     brouard  11490:     
1.126     brouard  11491:     /*---------- Forecasting ------------------*/
                   11492:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11493:     if(prevfcast==1){
                   11494:       /*    if(stepm ==1){*/
1.225     brouard  11495:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11496:     }
1.217     brouard  11497:     if(backcast==1){
1.219     brouard  11498:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11499:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11500:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11501: 
                   11502:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11503: 
                   11504:       bprlim=matrix(1,nlstate,1,nlstate);
                   11505:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11506:       fclose(ficresplb);
                   11507: 
1.222     brouard  11508:       hBijx(p, bage, fage, mobaverage);
                   11509:       fclose(ficrespijb);
1.219     brouard  11510:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11511: 
                   11512:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11513:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11514:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11515:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11516:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11517:     }
1.217     brouard  11518:     
1.186     brouard  11519:  
                   11520:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11521: 
1.215     brouard  11522:     free_ivector(wav,1,imx);
                   11523:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11524:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11525:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11526:                
                   11527:                
1.127     brouard  11528:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11529:                
1.201     brouard  11530:     strcpy(filerese,"E_");
                   11531:     strcat(filerese,fileresu);
1.126     brouard  11532:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11533:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11534:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11535:     }
1.208     brouard  11536:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11537:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11538: 
                   11539:     pstamp(ficreseij);
1.219     brouard  11540:                
1.235     brouard  11541:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11542:     if (cptcovn < 1){i1=1;}
                   11543:     
                   11544:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11545:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11546:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11547:        continue;
1.219     brouard  11548:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11549:       printf("\n#****** ");
1.225     brouard  11550:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11551:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11552:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11553:       }
                   11554:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11555:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11556:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11557:       }
                   11558:       fprintf(ficreseij,"******\n");
1.235     brouard  11559:       printf("******\n");
1.219     brouard  11560:       
                   11561:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11562:       oldm=oldms;savm=savms;
1.235     brouard  11563:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11564:       
1.219     brouard  11565:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11566:     }
                   11567:     fclose(ficreseij);
1.208     brouard  11568:     printf("done evsij\n");fflush(stdout);
                   11569:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11570:                
1.227     brouard  11571:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11572:                
                   11573:                
1.201     brouard  11574:     strcpy(filerest,"T_");
                   11575:     strcat(filerest,fileresu);
1.127     brouard  11576:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11577:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11578:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11579:     }
1.208     brouard  11580:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11581:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11582:                
1.126     brouard  11583: 
1.201     brouard  11584:     strcpy(fileresstde,"STDE_");
                   11585:     strcat(fileresstde,fileresu);
1.126     brouard  11586:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11587:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11588:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11589:     }
1.227     brouard  11590:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11591:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11592: 
1.201     brouard  11593:     strcpy(filerescve,"CVE_");
                   11594:     strcat(filerescve,fileresu);
1.126     brouard  11595:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11596:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11597:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11598:     }
1.227     brouard  11599:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11600:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11601: 
1.201     brouard  11602:     strcpy(fileresv,"V_");
                   11603:     strcat(fileresv,fileresu);
1.126     brouard  11604:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11605:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11606:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11607:     }
1.227     brouard  11608:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11609:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11610: 
1.145     brouard  11611:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11612:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11613:           
1.235     brouard  11614:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11615:     if (cptcovn < 1){i1=1;}
                   11616:     
                   11617:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11618:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11619:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11620:        continue;
1.242     brouard  11621:       printf("\n#****** Result for:");
                   11622:       fprintf(ficrest,"\n#****** Result for:");
                   11623:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11624:       for(j=1;j<=cptcoveff;j++){ 
                   11625:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11626:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11627:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11628:       }
1.235     brouard  11629:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11630:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11631:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11632:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11633:       }        
1.208     brouard  11634:       fprintf(ficrest,"******\n");
1.227     brouard  11635:       fprintf(ficlog,"******\n");
                   11636:       printf("******\n");
1.208     brouard  11637:       
                   11638:       fprintf(ficresstdeij,"\n#****** ");
                   11639:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11640:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11641:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11642:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11643:       }
1.235     brouard  11644:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11645:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11646:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11647:       }        
1.208     brouard  11648:       fprintf(ficresstdeij,"******\n");
                   11649:       fprintf(ficrescveij,"******\n");
                   11650:       
                   11651:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11652:       /* pstamp(ficresvij); */
1.225     brouard  11653:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11654:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11655:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11656:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11657:       }        
1.208     brouard  11658:       fprintf(ficresvij,"******\n");
                   11659:       
                   11660:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11661:       oldm=oldms;savm=savms;
1.235     brouard  11662:       printf(" cvevsij ");
                   11663:       fprintf(ficlog, " cvevsij ");
                   11664:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11665:       printf(" end cvevsij \n ");
                   11666:       fprintf(ficlog, " end cvevsij \n ");
                   11667:       
                   11668:       /*
                   11669:        */
                   11670:       /* goto endfree; */
                   11671:       
                   11672:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11673:       pstamp(ficrest);
                   11674:       
                   11675:       
                   11676:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11677:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11678:        cptcod= 0; /* To be deleted */
                   11679:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11680:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11681:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11682:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11683:        if(vpopbased==1)
                   11684:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11685:        else
                   11686:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11687:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11688:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11689:        fprintf(ficrest,"\n");
                   11690:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11691:        epj=vector(1,nlstate+1);
                   11692:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11693:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11694:        for(age=bage; age <=fage ;age++){
1.235     brouard  11695:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11696:          if (vpopbased==1) {
                   11697:            if(mobilav ==0){
                   11698:              for(i=1; i<=nlstate;i++)
                   11699:                prlim[i][i]=probs[(int)age][i][k];
                   11700:            }else{ /* mobilav */ 
                   11701:              for(i=1; i<=nlstate;i++)
                   11702:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11703:            }
                   11704:          }
1.219     brouard  11705:          
1.227     brouard  11706:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11707:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11708:          /* printf(" age %4.0f ",age); */
                   11709:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11710:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11711:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11712:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11713:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11714:            }
                   11715:            epj[nlstate+1] +=epj[j];
                   11716:          }
                   11717:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11718:          
1.227     brouard  11719:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11720:            for(j=1;j <=nlstate;j++)
                   11721:              vepp += vareij[i][j][(int)age];
                   11722:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11723:          for(j=1;j <=nlstate;j++){
                   11724:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11725:          }
                   11726:          fprintf(ficrest,"\n");
                   11727:        }
1.208     brouard  11728:       } /* End vpopbased */
                   11729:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11730:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11731:       free_vector(epj,1,nlstate+1);
1.235     brouard  11732:       printf("done selection\n");fflush(stdout);
                   11733:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11734:       
1.145     brouard  11735:       /*}*/
1.235     brouard  11736:     } /* End k selection */
1.227     brouard  11737: 
                   11738:     printf("done State-specific expectancies\n");fflush(stdout);
                   11739:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11740: 
1.126     brouard  11741:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11742:     
1.201     brouard  11743:     strcpy(fileresvpl,"VPL_");
                   11744:     strcat(fileresvpl,fileresu);
1.126     brouard  11745:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11746:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11747:       exit(0);
                   11748:     }
1.208     brouard  11749:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11750:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11751:     
1.145     brouard  11752:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11753:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11754:     
1.235     brouard  11755:     i1=pow(2,cptcoveff);
                   11756:     if (cptcovn < 1){i1=1;}
                   11757: 
                   11758:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11759:     for(k=1; k<=i1;k++){
1.253     brouard  11760:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11761:        continue;
1.227     brouard  11762:       fprintf(ficresvpl,"\n#****** ");
                   11763:       printf("\n#****** ");
                   11764:       fprintf(ficlog,"\n#****** ");
                   11765:       for(j=1;j<=cptcoveff;j++) {
                   11766:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11767:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11768:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11769:       }
1.235     brouard  11770:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11771:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11772:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11773:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11774:       }        
1.227     brouard  11775:       fprintf(ficresvpl,"******\n");
                   11776:       printf("******\n");
                   11777:       fprintf(ficlog,"******\n");
                   11778:       
                   11779:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11780:       oldm=oldms;savm=savms;
1.235     brouard  11781:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11782:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11783:       /*}*/
1.126     brouard  11784:     }
1.227     brouard  11785:     
1.126     brouard  11786:     fclose(ficresvpl);
1.208     brouard  11787:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11788:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11789:     
                   11790:     free_vector(weight,1,n);
                   11791:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11792:     free_imatrix(s,1,maxwav+1,1,n);
                   11793:     free_matrix(anint,1,maxwav,1,n); 
                   11794:     free_matrix(mint,1,maxwav,1,n);
                   11795:     free_ivector(cod,1,n);
                   11796:     free_ivector(tab,1,NCOVMAX);
                   11797:     fclose(ficresstdeij);
                   11798:     fclose(ficrescveij);
                   11799:     fclose(ficresvij);
                   11800:     fclose(ficrest);
                   11801:     fclose(ficpar);
                   11802:     
                   11803:     
1.126     brouard  11804:     /*---------- End : free ----------------*/
1.219     brouard  11805:     if (mobilav!=0 ||mobilavproj !=0)
                   11806:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11807:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11808:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11809:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11810:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11811:   /* endfree:*/
                   11812:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11813:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11814:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11815:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11816:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11817:   free_matrix(coqvar,1,maxwav,1,n);
                   11818:   free_matrix(covar,0,NCOVMAX,1,n);
                   11819:   free_matrix(matcov,1,npar,1,npar);
                   11820:   free_matrix(hess,1,npar,1,npar);
                   11821:   /*free_vector(delti,1,npar);*/
                   11822:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11823:   free_matrix(agev,1,maxwav,1,imx);
                   11824:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11825:   
                   11826:   free_ivector(ncodemax,1,NCOVMAX);
                   11827:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11828:   free_ivector(Dummy,-1,NCOVMAX);
                   11829:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11830:   free_ivector(DummyV,1,NCOVMAX);
                   11831:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11832:   free_ivector(Typevar,-1,NCOVMAX);
                   11833:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11834:   free_ivector(TvarsQ,1,NCOVMAX);
                   11835:   free_ivector(TvarsQind,1,NCOVMAX);
                   11836:   free_ivector(TvarsD,1,NCOVMAX);
                   11837:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11838:   free_ivector(TvarFD,1,NCOVMAX);
                   11839:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11840:   free_ivector(TvarF,1,NCOVMAX);
                   11841:   free_ivector(TvarFind,1,NCOVMAX);
                   11842:   free_ivector(TvarV,1,NCOVMAX);
                   11843:   free_ivector(TvarVind,1,NCOVMAX);
                   11844:   free_ivector(TvarA,1,NCOVMAX);
                   11845:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11846:   free_ivector(TvarFQ,1,NCOVMAX);
                   11847:   free_ivector(TvarFQind,1,NCOVMAX);
                   11848:   free_ivector(TvarVD,1,NCOVMAX);
                   11849:   free_ivector(TvarVDind,1,NCOVMAX);
                   11850:   free_ivector(TvarVQ,1,NCOVMAX);
                   11851:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11852:   free_ivector(Tvarsel,1,NCOVMAX);
                   11853:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11854:   free_ivector(Tposprod,1,NCOVMAX);
                   11855:   free_ivector(Tprod,1,NCOVMAX);
                   11856:   free_ivector(Tvaraff,1,NCOVMAX);
                   11857:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11858:   free_ivector(Tage,1,NCOVMAX);
                   11859:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11860:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11861:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11862:   
                   11863:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11864:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11865:   fflush(fichtm);
                   11866:   fflush(ficgp);
                   11867:   
1.227     brouard  11868:   
1.126     brouard  11869:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11870:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11871:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11872:   }else{
                   11873:     printf("End of Imach\n");
                   11874:     fprintf(ficlog,"End of Imach\n");
                   11875:   }
                   11876:   printf("See log file on %s\n",filelog);
                   11877:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11878:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11879:   rend_time = time(NULL);  
                   11880:   end_time = *localtime(&rend_time);
                   11881:   /* tml = *localtime(&end_time.tm_sec); */
                   11882:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11883:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11884:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11885:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11886:   
1.157     brouard  11887:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11888:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11889:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11890:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11891: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11892:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11893:   fclose(fichtm);
                   11894:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11895:   fclose(fichtmcov);
                   11896:   fclose(ficgp);
                   11897:   fclose(ficlog);
                   11898:   /*------ End -----------*/
1.227     brouard  11899:   
                   11900:   
                   11901:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11902: #ifdef WIN32
1.227     brouard  11903:   if (_chdir(pathcd) != 0)
                   11904:     printf("Can't move to directory %s!\n",path);
                   11905:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11906: #else
1.227     brouard  11907:     if(chdir(pathcd) != 0)
                   11908:       printf("Can't move to directory %s!\n", path);
                   11909:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11910: #endif 
1.126     brouard  11911:     printf("Current directory %s!\n",pathcd);
                   11912:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11913:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11914: #ifdef _WIN32
1.126     brouard  11915:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11916: #endif
                   11917:   if(!stat(plotcmd,&info)){
1.158     brouard  11918:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11919:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11920:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11921:     }else
                   11922:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11923: #ifdef __unix
1.126     brouard  11924:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11925:     if(!stat(plotcmd,&info)){
1.158     brouard  11926:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11927:     }else
                   11928:       strcpy(pplotcmd,plotcmd);
                   11929: #endif
                   11930:   }else
                   11931:     strcpy(pplotcmd,plotcmd);
                   11932:   
                   11933:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11934:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11935:   
1.126     brouard  11936:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11937:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11938:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11939:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11940:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11941:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11942:   }
1.158     brouard  11943:   printf(" Successful, please wait...");
1.126     brouard  11944:   while (z[0] != 'q') {
                   11945:     /* chdir(path); */
1.154     brouard  11946:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11947:     scanf("%s",z);
                   11948: /*     if (z[0] == 'c') system("./imach"); */
                   11949:     if (z[0] == 'e') {
1.158     brouard  11950: #ifdef __APPLE__
1.152     brouard  11951:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11952: #elif __linux
                   11953:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11954: #else
1.152     brouard  11955:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11956: #endif
                   11957:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11958:       system(pplotcmd);
1.126     brouard  11959:     }
                   11960:     else if (z[0] == 'g') system(plotcmd);
                   11961:     else if (z[0] == 'q') exit(0);
                   11962:   }
1.227     brouard  11963: end:
1.126     brouard  11964:   while (z[0] != 'q') {
1.195     brouard  11965:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11966:     scanf("%s",z);
                   11967:   }
                   11968: }

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