Annotation of imach/src/imach.c, revision 1.265

1.265   ! brouard     1: /* $Id: imach.c,v 1.264 2017/04/26 06:01:29 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.265   ! brouard     4:   Revision 1.264  2017/04/26 06:01:29  brouard
        !             5:   Summary: Labels in graphs
        !             6: 
1.264     brouard     7:   Revision 1.263  2017/04/24 15:23:15  brouard
                      8:   Summary: to save
                      9: 
1.263     brouard    10:   Revision 1.262  2017/04/18 16:48:12  brouard
                     11:   *** empty log message ***
                     12: 
1.262     brouard    13:   Revision 1.261  2017/04/05 10:14:09  brouard
                     14:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     15: 
1.261     brouard    16:   Revision 1.260  2017/04/04 17:46:59  brouard
                     17:   Summary: Gnuplot indexations fixed (humm)
                     18: 
1.260     brouard    19:   Revision 1.259  2017/04/04 13:01:16  brouard
                     20:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     21: 
1.259     brouard    22:   Revision 1.258  2017/04/03 10:17:47  brouard
                     23:   Summary: Version 0.99r12
                     24: 
                     25:   Some cleanings, conformed with updated documentation.
                     26: 
1.258     brouard    27:   Revision 1.257  2017/03/29 16:53:30  brouard
                     28:   Summary: Temp
                     29: 
1.257     brouard    30:   Revision 1.256  2017/03/27 05:50:23  brouard
                     31:   Summary: Temporary
                     32: 
1.256     brouard    33:   Revision 1.255  2017/03/08 16:02:28  brouard
                     34:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     35: 
1.255     brouard    36:   Revision 1.254  2017/03/08 07:13:00  brouard
                     37:   Summary: Fixing data parameter line
                     38: 
1.254     brouard    39:   Revision 1.253  2016/12/15 11:59:41  brouard
                     40:   Summary: 0.99 in progress
                     41: 
1.253     brouard    42:   Revision 1.252  2016/09/15 21:15:37  brouard
                     43:   *** empty log message ***
                     44: 
1.252     brouard    45:   Revision 1.251  2016/09/15 15:01:13  brouard
                     46:   Summary: not working
                     47: 
1.251     brouard    48:   Revision 1.250  2016/09/08 16:07:27  brouard
                     49:   Summary: continue
                     50: 
1.250     brouard    51:   Revision 1.249  2016/09/07 17:14:18  brouard
                     52:   Summary: Starting values from frequencies
                     53: 
1.249     brouard    54:   Revision 1.248  2016/09/07 14:10:18  brouard
                     55:   *** empty log message ***
                     56: 
1.248     brouard    57:   Revision 1.247  2016/09/02 11:11:21  brouard
                     58:   *** empty log message ***
                     59: 
1.247     brouard    60:   Revision 1.246  2016/09/02 08:49:22  brouard
                     61:   *** empty log message ***
                     62: 
1.246     brouard    63:   Revision 1.245  2016/09/02 07:25:01  brouard
                     64:   *** empty log message ***
                     65: 
1.245     brouard    66:   Revision 1.244  2016/09/02 07:17:34  brouard
                     67:   *** empty log message ***
                     68: 
1.244     brouard    69:   Revision 1.243  2016/09/02 06:45:35  brouard
                     70:   *** empty log message ***
                     71: 
1.243     brouard    72:   Revision 1.242  2016/08/30 15:01:20  brouard
                     73:   Summary: Fixing a lots
                     74: 
1.242     brouard    75:   Revision 1.241  2016/08/29 17:17:25  brouard
                     76:   Summary: gnuplot problem in Back projection to fix
                     77: 
1.241     brouard    78:   Revision 1.240  2016/08/29 07:53:18  brouard
                     79:   Summary: Better
                     80: 
1.240     brouard    81:   Revision 1.239  2016/08/26 15:51:03  brouard
                     82:   Summary: Improvement in Powell output in order to copy and paste
                     83: 
                     84:   Author:
                     85: 
1.239     brouard    86:   Revision 1.238  2016/08/26 14:23:35  brouard
                     87:   Summary: Starting tests of 0.99
                     88: 
1.238     brouard    89:   Revision 1.237  2016/08/26 09:20:19  brouard
                     90:   Summary: to valgrind
                     91: 
1.237     brouard    92:   Revision 1.236  2016/08/25 10:50:18  brouard
                     93:   *** empty log message ***
                     94: 
1.236     brouard    95:   Revision 1.235  2016/08/25 06:59:23  brouard
                     96:   *** empty log message ***
                     97: 
1.235     brouard    98:   Revision 1.234  2016/08/23 16:51:20  brouard
                     99:   *** empty log message ***
                    100: 
1.234     brouard   101:   Revision 1.233  2016/08/23 07:40:50  brouard
                    102:   Summary: not working
                    103: 
1.233     brouard   104:   Revision 1.232  2016/08/22 14:20:21  brouard
                    105:   Summary: not working
                    106: 
1.232     brouard   107:   Revision 1.231  2016/08/22 07:17:15  brouard
                    108:   Summary: not working
                    109: 
1.231     brouard   110:   Revision 1.230  2016/08/22 06:55:53  brouard
                    111:   Summary: Not working
                    112: 
1.230     brouard   113:   Revision 1.229  2016/07/23 09:45:53  brouard
                    114:   Summary: Completing for func too
                    115: 
1.229     brouard   116:   Revision 1.228  2016/07/22 17:45:30  brouard
                    117:   Summary: Fixing some arrays, still debugging
                    118: 
1.227     brouard   119:   Revision 1.226  2016/07/12 18:42:34  brouard
                    120:   Summary: temp
                    121: 
1.226     brouard   122:   Revision 1.225  2016/07/12 08:40:03  brouard
                    123:   Summary: saving but not running
                    124: 
1.225     brouard   125:   Revision 1.224  2016/07/01 13:16:01  brouard
                    126:   Summary: Fixes
                    127: 
1.224     brouard   128:   Revision 1.223  2016/02/19 09:23:35  brouard
                    129:   Summary: temporary
                    130: 
1.223     brouard   131:   Revision 1.222  2016/02/17 08:14:50  brouard
                    132:   Summary: Probably last 0.98 stable version 0.98r6
                    133: 
1.222     brouard   134:   Revision 1.221  2016/02/15 23:35:36  brouard
                    135:   Summary: minor bug
                    136: 
1.220     brouard   137:   Revision 1.219  2016/02/15 00:48:12  brouard
                    138:   *** empty log message ***
                    139: 
1.219     brouard   140:   Revision 1.218  2016/02/12 11:29:23  brouard
                    141:   Summary: 0.99 Back projections
                    142: 
1.218     brouard   143:   Revision 1.217  2015/12/23 17:18:31  brouard
                    144:   Summary: Experimental backcast
                    145: 
1.217     brouard   146:   Revision 1.216  2015/12/18 17:32:11  brouard
                    147:   Summary: 0.98r4 Warning and status=-2
                    148: 
                    149:   Version 0.98r4 is now:
                    150:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    151:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    152:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    153: 
1.216     brouard   154:   Revision 1.215  2015/12/16 08:52:24  brouard
                    155:   Summary: 0.98r4 working
                    156: 
1.215     brouard   157:   Revision 1.214  2015/12/16 06:57:54  brouard
                    158:   Summary: temporary not working
                    159: 
1.214     brouard   160:   Revision 1.213  2015/12/11 18:22:17  brouard
                    161:   Summary: 0.98r4
                    162: 
1.213     brouard   163:   Revision 1.212  2015/11/21 12:47:24  brouard
                    164:   Summary: minor typo
                    165: 
1.212     brouard   166:   Revision 1.211  2015/11/21 12:41:11  brouard
                    167:   Summary: 0.98r3 with some graph of projected cross-sectional
                    168: 
                    169:   Author: Nicolas Brouard
                    170: 
1.211     brouard   171:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   172:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   173:   Summary: Adding ftolpl parameter
                    174:   Author: N Brouard
                    175: 
                    176:   We had difficulties to get smoothed confidence intervals. It was due
                    177:   to the period prevalence which wasn't computed accurately. The inner
                    178:   parameter ftolpl is now an outer parameter of the .imach parameter
                    179:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    180:   computation are long.
                    181: 
1.209     brouard   182:   Revision 1.208  2015/11/17 14:31:57  brouard
                    183:   Summary: temporary
                    184: 
1.208     brouard   185:   Revision 1.207  2015/10/27 17:36:57  brouard
                    186:   *** empty log message ***
                    187: 
1.207     brouard   188:   Revision 1.206  2015/10/24 07:14:11  brouard
                    189:   *** empty log message ***
                    190: 
1.206     brouard   191:   Revision 1.205  2015/10/23 15:50:53  brouard
                    192:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    193: 
1.205     brouard   194:   Revision 1.204  2015/10/01 16:20:26  brouard
                    195:   Summary: Some new graphs of contribution to likelihood
                    196: 
1.204     brouard   197:   Revision 1.203  2015/09/30 17:45:14  brouard
                    198:   Summary: looking at better estimation of the hessian
                    199: 
                    200:   Also a better criteria for convergence to the period prevalence And
                    201:   therefore adding the number of years needed to converge. (The
                    202:   prevalence in any alive state shold sum to one
                    203: 
1.203     brouard   204:   Revision 1.202  2015/09/22 19:45:16  brouard
                    205:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    206: 
1.202     brouard   207:   Revision 1.201  2015/09/15 17:34:58  brouard
                    208:   Summary: 0.98r0
                    209: 
                    210:   - Some new graphs like suvival functions
                    211:   - Some bugs fixed like model=1+age+V2.
                    212: 
1.201     brouard   213:   Revision 1.200  2015/09/09 16:53:55  brouard
                    214:   Summary: Big bug thanks to Flavia
                    215: 
                    216:   Even model=1+age+V2. did not work anymore
                    217: 
1.200     brouard   218:   Revision 1.199  2015/09/07 14:09:23  brouard
                    219:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    220: 
1.199     brouard   221:   Revision 1.198  2015/09/03 07:14:39  brouard
                    222:   Summary: 0.98q5 Flavia
                    223: 
1.198     brouard   224:   Revision 1.197  2015/09/01 18:24:39  brouard
                    225:   *** empty log message ***
                    226: 
1.197     brouard   227:   Revision 1.196  2015/08/18 23:17:52  brouard
                    228:   Summary: 0.98q5
                    229: 
1.196     brouard   230:   Revision 1.195  2015/08/18 16:28:39  brouard
                    231:   Summary: Adding a hack for testing purpose
                    232: 
                    233:   After reading the title, ftol and model lines, if the comment line has
                    234:   a q, starting with #q, the answer at the end of the run is quit. It
                    235:   permits to run test files in batch with ctest. The former workaround was
                    236:   $ echo q | imach foo.imach
                    237: 
1.195     brouard   238:   Revision 1.194  2015/08/18 13:32:00  brouard
                    239:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    240: 
1.194     brouard   241:   Revision 1.193  2015/08/04 07:17:42  brouard
                    242:   Summary: 0.98q4
                    243: 
1.193     brouard   244:   Revision 1.192  2015/07/16 16:49:02  brouard
                    245:   Summary: Fixing some outputs
                    246: 
1.192     brouard   247:   Revision 1.191  2015/07/14 10:00:33  brouard
                    248:   Summary: Some fixes
                    249: 
1.191     brouard   250:   Revision 1.190  2015/05/05 08:51:13  brouard
                    251:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    252: 
                    253:   Fix 1+age+.
                    254: 
1.190     brouard   255:   Revision 1.189  2015/04/30 14:45:16  brouard
                    256:   Summary: 0.98q2
                    257: 
1.189     brouard   258:   Revision 1.188  2015/04/30 08:27:53  brouard
                    259:   *** empty log message ***
                    260: 
1.188     brouard   261:   Revision 1.187  2015/04/29 09:11:15  brouard
                    262:   *** empty log message ***
                    263: 
1.187     brouard   264:   Revision 1.186  2015/04/23 12:01:52  brouard
                    265:   Summary: V1*age is working now, version 0.98q1
                    266: 
                    267:   Some codes had been disabled in order to simplify and Vn*age was
                    268:   working in the optimization phase, ie, giving correct MLE parameters,
                    269:   but, as usual, outputs were not correct and program core dumped.
                    270: 
1.186     brouard   271:   Revision 1.185  2015/03/11 13:26:42  brouard
                    272:   Summary: Inclusion of compile and links command line for Intel Compiler
                    273: 
1.185     brouard   274:   Revision 1.184  2015/03/11 11:52:39  brouard
                    275:   Summary: Back from Windows 8. Intel Compiler
                    276: 
1.184     brouard   277:   Revision 1.183  2015/03/10 20:34:32  brouard
                    278:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    279: 
                    280:   We use directest instead of original Powell test; probably no
                    281:   incidence on the results, but better justifications;
                    282:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    283:   wrong results.
                    284: 
1.183     brouard   285:   Revision 1.182  2015/02/12 08:19:57  brouard
                    286:   Summary: Trying to keep directest which seems simpler and more general
                    287:   Author: Nicolas Brouard
                    288: 
1.182     brouard   289:   Revision 1.181  2015/02/11 23:22:24  brouard
                    290:   Summary: Comments on Powell added
                    291: 
                    292:   Author:
                    293: 
1.181     brouard   294:   Revision 1.180  2015/02/11 17:33:45  brouard
                    295:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    296: 
1.180     brouard   297:   Revision 1.179  2015/01/04 09:57:06  brouard
                    298:   Summary: back to OS/X
                    299: 
1.179     brouard   300:   Revision 1.178  2015/01/04 09:35:48  brouard
                    301:   *** empty log message ***
                    302: 
1.178     brouard   303:   Revision 1.177  2015/01/03 18:40:56  brouard
                    304:   Summary: Still testing ilc32 on OSX
                    305: 
1.177     brouard   306:   Revision 1.176  2015/01/03 16:45:04  brouard
                    307:   *** empty log message ***
                    308: 
1.176     brouard   309:   Revision 1.175  2015/01/03 16:33:42  brouard
                    310:   *** empty log message ***
                    311: 
1.175     brouard   312:   Revision 1.174  2015/01/03 16:15:49  brouard
                    313:   Summary: Still in cross-compilation
                    314: 
1.174     brouard   315:   Revision 1.173  2015/01/03 12:06:26  brouard
                    316:   Summary: trying to detect cross-compilation
                    317: 
1.173     brouard   318:   Revision 1.172  2014/12/27 12:07:47  brouard
                    319:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    320: 
1.172     brouard   321:   Revision 1.171  2014/12/23 13:26:59  brouard
                    322:   Summary: Back from Visual C
                    323: 
                    324:   Still problem with utsname.h on Windows
                    325: 
1.171     brouard   326:   Revision 1.170  2014/12/23 11:17:12  brouard
                    327:   Summary: Cleaning some \%% back to %%
                    328: 
                    329:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    330: 
1.170     brouard   331:   Revision 1.169  2014/12/22 23:08:31  brouard
                    332:   Summary: 0.98p
                    333: 
                    334:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    335: 
1.169     brouard   336:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   337:   Summary: update
1.169     brouard   338: 
1.168     brouard   339:   Revision 1.167  2014/12/22 13:50:56  brouard
                    340:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    341: 
                    342:   Testing on Linux 64
                    343: 
1.167     brouard   344:   Revision 1.166  2014/12/22 11:40:47  brouard
                    345:   *** empty log message ***
                    346: 
1.166     brouard   347:   Revision 1.165  2014/12/16 11:20:36  brouard
                    348:   Summary: After compiling on Visual C
                    349: 
                    350:   * imach.c (Module): Merging 1.61 to 1.162
                    351: 
1.165     brouard   352:   Revision 1.164  2014/12/16 10:52:11  brouard
                    353:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    354: 
                    355:   * imach.c (Module): Merging 1.61 to 1.162
                    356: 
1.164     brouard   357:   Revision 1.163  2014/12/16 10:30:11  brouard
                    358:   * imach.c (Module): Merging 1.61 to 1.162
                    359: 
1.163     brouard   360:   Revision 1.162  2014/09/25 11:43:39  brouard
                    361:   Summary: temporary backup 0.99!
                    362: 
1.162     brouard   363:   Revision 1.1  2014/09/16 11:06:58  brouard
                    364:   Summary: With some code (wrong) for nlopt
                    365: 
                    366:   Author:
                    367: 
                    368:   Revision 1.161  2014/09/15 20:41:41  brouard
                    369:   Summary: Problem with macro SQR on Intel compiler
                    370: 
1.161     brouard   371:   Revision 1.160  2014/09/02 09:24:05  brouard
                    372:   *** empty log message ***
                    373: 
1.160     brouard   374:   Revision 1.159  2014/09/01 10:34:10  brouard
                    375:   Summary: WIN32
                    376:   Author: Brouard
                    377: 
1.159     brouard   378:   Revision 1.158  2014/08/27 17:11:51  brouard
                    379:   *** empty log message ***
                    380: 
1.158     brouard   381:   Revision 1.157  2014/08/27 16:26:55  brouard
                    382:   Summary: Preparing windows Visual studio version
                    383:   Author: Brouard
                    384: 
                    385:   In order to compile on Visual studio, time.h is now correct and time_t
                    386:   and tm struct should be used. difftime should be used but sometimes I
                    387:   just make the differences in raw time format (time(&now).
                    388:   Trying to suppress #ifdef LINUX
                    389:   Add xdg-open for __linux in order to open default browser.
                    390: 
1.157     brouard   391:   Revision 1.156  2014/08/25 20:10:10  brouard
                    392:   *** empty log message ***
                    393: 
1.156     brouard   394:   Revision 1.155  2014/08/25 18:32:34  brouard
                    395:   Summary: New compile, minor changes
                    396:   Author: Brouard
                    397: 
1.155     brouard   398:   Revision 1.154  2014/06/20 17:32:08  brouard
                    399:   Summary: Outputs now all graphs of convergence to period prevalence
                    400: 
1.154     brouard   401:   Revision 1.153  2014/06/20 16:45:46  brouard
                    402:   Summary: If 3 live state, convergence to period prevalence on same graph
                    403:   Author: Brouard
                    404: 
1.153     brouard   405:   Revision 1.152  2014/06/18 17:54:09  brouard
                    406:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    407: 
1.152     brouard   408:   Revision 1.151  2014/06/18 16:43:30  brouard
                    409:   *** empty log message ***
                    410: 
1.151     brouard   411:   Revision 1.150  2014/06/18 16:42:35  brouard
                    412:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    413:   Author: brouard
                    414: 
1.150     brouard   415:   Revision 1.149  2014/06/18 15:51:14  brouard
                    416:   Summary: Some fixes in parameter files errors
                    417:   Author: Nicolas Brouard
                    418: 
1.149     brouard   419:   Revision 1.148  2014/06/17 17:38:48  brouard
                    420:   Summary: Nothing new
                    421:   Author: Brouard
                    422: 
                    423:   Just a new packaging for OS/X version 0.98nS
                    424: 
1.148     brouard   425:   Revision 1.147  2014/06/16 10:33:11  brouard
                    426:   *** empty log message ***
                    427: 
1.147     brouard   428:   Revision 1.146  2014/06/16 10:20:28  brouard
                    429:   Summary: Merge
                    430:   Author: Brouard
                    431: 
                    432:   Merge, before building revised version.
                    433: 
1.146     brouard   434:   Revision 1.145  2014/06/10 21:23:15  brouard
                    435:   Summary: Debugging with valgrind
                    436:   Author: Nicolas Brouard
                    437: 
                    438:   Lot of changes in order to output the results with some covariates
                    439:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    440:   improve the code.
                    441:   No more memory valgrind error but a lot has to be done in order to
                    442:   continue the work of splitting the code into subroutines.
                    443:   Also, decodemodel has been improved. Tricode is still not
                    444:   optimal. nbcode should be improved. Documentation has been added in
                    445:   the source code.
                    446: 
1.144     brouard   447:   Revision 1.143  2014/01/26 09:45:38  brouard
                    448:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    449: 
                    450:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    451:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    452: 
1.143     brouard   453:   Revision 1.142  2014/01/26 03:57:36  brouard
                    454:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    455: 
                    456:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    457: 
1.142     brouard   458:   Revision 1.141  2014/01/26 02:42:01  brouard
                    459:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    460: 
1.141     brouard   461:   Revision 1.140  2011/09/02 10:37:54  brouard
                    462:   Summary: times.h is ok with mingw32 now.
                    463: 
1.140     brouard   464:   Revision 1.139  2010/06/14 07:50:17  brouard
                    465:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    466:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    467: 
1.139     brouard   468:   Revision 1.138  2010/04/30 18:19:40  brouard
                    469:   *** empty log message ***
                    470: 
1.138     brouard   471:   Revision 1.137  2010/04/29 18:11:38  brouard
                    472:   (Module): Checking covariates for more complex models
                    473:   than V1+V2. A lot of change to be done. Unstable.
                    474: 
1.137     brouard   475:   Revision 1.136  2010/04/26 20:30:53  brouard
                    476:   (Module): merging some libgsl code. Fixing computation
                    477:   of likelione (using inter/intrapolation if mle = 0) in order to
                    478:   get same likelihood as if mle=1.
                    479:   Some cleaning of code and comments added.
                    480: 
1.136     brouard   481:   Revision 1.135  2009/10/29 15:33:14  brouard
                    482:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    483: 
1.135     brouard   484:   Revision 1.134  2009/10/29 13:18:53  brouard
                    485:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    486: 
1.134     brouard   487:   Revision 1.133  2009/07/06 10:21:25  brouard
                    488:   just nforces
                    489: 
1.133     brouard   490:   Revision 1.132  2009/07/06 08:22:05  brouard
                    491:   Many tings
                    492: 
1.132     brouard   493:   Revision 1.131  2009/06/20 16:22:47  brouard
                    494:   Some dimensions resccaled
                    495: 
1.131     brouard   496:   Revision 1.130  2009/05/26 06:44:34  brouard
                    497:   (Module): Max Covariate is now set to 20 instead of 8. A
                    498:   lot of cleaning with variables initialized to 0. Trying to make
                    499:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    500: 
1.130     brouard   501:   Revision 1.129  2007/08/31 13:49:27  lievre
                    502:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    503: 
1.129     lievre    504:   Revision 1.128  2006/06/30 13:02:05  brouard
                    505:   (Module): Clarifications on computing e.j
                    506: 
1.128     brouard   507:   Revision 1.127  2006/04/28 18:11:50  brouard
                    508:   (Module): Yes the sum of survivors was wrong since
                    509:   imach-114 because nhstepm was no more computed in the age
                    510:   loop. Now we define nhstepma in the age loop.
                    511:   (Module): In order to speed up (in case of numerous covariates) we
                    512:   compute health expectancies (without variances) in a first step
                    513:   and then all the health expectancies with variances or standard
                    514:   deviation (needs data from the Hessian matrices) which slows the
                    515:   computation.
                    516:   In the future we should be able to stop the program is only health
                    517:   expectancies and graph are needed without standard deviations.
                    518: 
1.127     brouard   519:   Revision 1.126  2006/04/28 17:23:28  brouard
                    520:   (Module): Yes the sum of survivors was wrong since
                    521:   imach-114 because nhstepm was no more computed in the age
                    522:   loop. Now we define nhstepma in the age loop.
                    523:   Version 0.98h
                    524: 
1.126     brouard   525:   Revision 1.125  2006/04/04 15:20:31  lievre
                    526:   Errors in calculation of health expectancies. Age was not initialized.
                    527:   Forecasting file added.
                    528: 
                    529:   Revision 1.124  2006/03/22 17:13:53  lievre
                    530:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    531:   The log-likelihood is printed in the log file
                    532: 
                    533:   Revision 1.123  2006/03/20 10:52:43  brouard
                    534:   * imach.c (Module): <title> changed, corresponds to .htm file
                    535:   name. <head> headers where missing.
                    536: 
                    537:   * imach.c (Module): Weights can have a decimal point as for
                    538:   English (a comma might work with a correct LC_NUMERIC environment,
                    539:   otherwise the weight is truncated).
                    540:   Modification of warning when the covariates values are not 0 or
                    541:   1.
                    542:   Version 0.98g
                    543: 
                    544:   Revision 1.122  2006/03/20 09:45:41  brouard
                    545:   (Module): Weights can have a decimal point as for
                    546:   English (a comma might work with a correct LC_NUMERIC environment,
                    547:   otherwise the weight is truncated).
                    548:   Modification of warning when the covariates values are not 0 or
                    549:   1.
                    550:   Version 0.98g
                    551: 
                    552:   Revision 1.121  2006/03/16 17:45:01  lievre
                    553:   * imach.c (Module): Comments concerning covariates added
                    554: 
                    555:   * imach.c (Module): refinements in the computation of lli if
                    556:   status=-2 in order to have more reliable computation if stepm is
                    557:   not 1 month. Version 0.98f
                    558: 
                    559:   Revision 1.120  2006/03/16 15:10:38  lievre
                    560:   (Module): refinements in the computation of lli if
                    561:   status=-2 in order to have more reliable computation if stepm is
                    562:   not 1 month. Version 0.98f
                    563: 
                    564:   Revision 1.119  2006/03/15 17:42:26  brouard
                    565:   (Module): Bug if status = -2, the loglikelihood was
                    566:   computed as likelihood omitting the logarithm. Version O.98e
                    567: 
                    568:   Revision 1.118  2006/03/14 18:20:07  brouard
                    569:   (Module): varevsij Comments added explaining the second
                    570:   table of variances if popbased=1 .
                    571:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    572:   (Module): Function pstamp added
                    573:   (Module): Version 0.98d
                    574: 
                    575:   Revision 1.117  2006/03/14 17:16:22  brouard
                    576:   (Module): varevsij Comments added explaining the second
                    577:   table of variances if popbased=1 .
                    578:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    579:   (Module): Function pstamp added
                    580:   (Module): Version 0.98d
                    581: 
                    582:   Revision 1.116  2006/03/06 10:29:27  brouard
                    583:   (Module): Variance-covariance wrong links and
                    584:   varian-covariance of ej. is needed (Saito).
                    585: 
                    586:   Revision 1.115  2006/02/27 12:17:45  brouard
                    587:   (Module): One freematrix added in mlikeli! 0.98c
                    588: 
                    589:   Revision 1.114  2006/02/26 12:57:58  brouard
                    590:   (Module): Some improvements in processing parameter
                    591:   filename with strsep.
                    592: 
                    593:   Revision 1.113  2006/02/24 14:20:24  brouard
                    594:   (Module): Memory leaks checks with valgrind and:
                    595:   datafile was not closed, some imatrix were not freed and on matrix
                    596:   allocation too.
                    597: 
                    598:   Revision 1.112  2006/01/30 09:55:26  brouard
                    599:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    600: 
                    601:   Revision 1.111  2006/01/25 20:38:18  brouard
                    602:   (Module): Lots of cleaning and bugs added (Gompertz)
                    603:   (Module): Comments can be added in data file. Missing date values
                    604:   can be a simple dot '.'.
                    605: 
                    606:   Revision 1.110  2006/01/25 00:51:50  brouard
                    607:   (Module): Lots of cleaning and bugs added (Gompertz)
                    608: 
                    609:   Revision 1.109  2006/01/24 19:37:15  brouard
                    610:   (Module): Comments (lines starting with a #) are allowed in data.
                    611: 
                    612:   Revision 1.108  2006/01/19 18:05:42  lievre
                    613:   Gnuplot problem appeared...
                    614:   To be fixed
                    615: 
                    616:   Revision 1.107  2006/01/19 16:20:37  brouard
                    617:   Test existence of gnuplot in imach path
                    618: 
                    619:   Revision 1.106  2006/01/19 13:24:36  brouard
                    620:   Some cleaning and links added in html output
                    621: 
                    622:   Revision 1.105  2006/01/05 20:23:19  lievre
                    623:   *** empty log message ***
                    624: 
                    625:   Revision 1.104  2005/09/30 16:11:43  lievre
                    626:   (Module): sump fixed, loop imx fixed, and simplifications.
                    627:   (Module): If the status is missing at the last wave but we know
                    628:   that the person is alive, then we can code his/her status as -2
                    629:   (instead of missing=-1 in earlier versions) and his/her
                    630:   contributions to the likelihood is 1 - Prob of dying from last
                    631:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    632:   the healthy state at last known wave). Version is 0.98
                    633: 
                    634:   Revision 1.103  2005/09/30 15:54:49  lievre
                    635:   (Module): sump fixed, loop imx fixed, and simplifications.
                    636: 
                    637:   Revision 1.102  2004/09/15 17:31:30  brouard
                    638:   Add the possibility to read data file including tab characters.
                    639: 
                    640:   Revision 1.101  2004/09/15 10:38:38  brouard
                    641:   Fix on curr_time
                    642: 
                    643:   Revision 1.100  2004/07/12 18:29:06  brouard
                    644:   Add version for Mac OS X. Just define UNIX in Makefile
                    645: 
                    646:   Revision 1.99  2004/06/05 08:57:40  brouard
                    647:   *** empty log message ***
                    648: 
                    649:   Revision 1.98  2004/05/16 15:05:56  brouard
                    650:   New version 0.97 . First attempt to estimate force of mortality
                    651:   directly from the data i.e. without the need of knowing the health
                    652:   state at each age, but using a Gompertz model: log u =a + b*age .
                    653:   This is the basic analysis of mortality and should be done before any
                    654:   other analysis, in order to test if the mortality estimated from the
                    655:   cross-longitudinal survey is different from the mortality estimated
                    656:   from other sources like vital statistic data.
                    657: 
                    658:   The same imach parameter file can be used but the option for mle should be -3.
                    659: 
1.133     brouard   660:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   661:   former routines in order to include the new code within the former code.
                    662: 
                    663:   The output is very simple: only an estimate of the intercept and of
                    664:   the slope with 95% confident intervals.
                    665: 
                    666:   Current limitations:
                    667:   A) Even if you enter covariates, i.e. with the
                    668:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    669:   B) There is no computation of Life Expectancy nor Life Table.
                    670: 
                    671:   Revision 1.97  2004/02/20 13:25:42  lievre
                    672:   Version 0.96d. Population forecasting command line is (temporarily)
                    673:   suppressed.
                    674: 
                    675:   Revision 1.96  2003/07/15 15:38:55  brouard
                    676:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    677:   rewritten within the same printf. Workaround: many printfs.
                    678: 
                    679:   Revision 1.95  2003/07/08 07:54:34  brouard
                    680:   * imach.c (Repository):
                    681:   (Repository): Using imachwizard code to output a more meaningful covariance
                    682:   matrix (cov(a12,c31) instead of numbers.
                    683: 
                    684:   Revision 1.94  2003/06/27 13:00:02  brouard
                    685:   Just cleaning
                    686: 
                    687:   Revision 1.93  2003/06/25 16:33:55  brouard
                    688:   (Module): On windows (cygwin) function asctime_r doesn't
                    689:   exist so I changed back to asctime which exists.
                    690:   (Module): Version 0.96b
                    691: 
                    692:   Revision 1.92  2003/06/25 16:30:45  brouard
                    693:   (Module): On windows (cygwin) function asctime_r doesn't
                    694:   exist so I changed back to asctime which exists.
                    695: 
                    696:   Revision 1.91  2003/06/25 15:30:29  brouard
                    697:   * imach.c (Repository): Duplicated warning errors corrected.
                    698:   (Repository): Elapsed time after each iteration is now output. It
                    699:   helps to forecast when convergence will be reached. Elapsed time
                    700:   is stamped in powell.  We created a new html file for the graphs
                    701:   concerning matrix of covariance. It has extension -cov.htm.
                    702: 
                    703:   Revision 1.90  2003/06/24 12:34:15  brouard
                    704:   (Module): Some bugs corrected for windows. Also, when
                    705:   mle=-1 a template is output in file "or"mypar.txt with the design
                    706:   of the covariance matrix to be input.
                    707: 
                    708:   Revision 1.89  2003/06/24 12:30:52  brouard
                    709:   (Module): Some bugs corrected for windows. Also, when
                    710:   mle=-1 a template is output in file "or"mypar.txt with the design
                    711:   of the covariance matrix to be input.
                    712: 
                    713:   Revision 1.88  2003/06/23 17:54:56  brouard
                    714:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    715: 
                    716:   Revision 1.87  2003/06/18 12:26:01  brouard
                    717:   Version 0.96
                    718: 
                    719:   Revision 1.86  2003/06/17 20:04:08  brouard
                    720:   (Module): Change position of html and gnuplot routines and added
                    721:   routine fileappend.
                    722: 
                    723:   Revision 1.85  2003/06/17 13:12:43  brouard
                    724:   * imach.c (Repository): Check when date of death was earlier that
                    725:   current date of interview. It may happen when the death was just
                    726:   prior to the death. In this case, dh was negative and likelihood
                    727:   was wrong (infinity). We still send an "Error" but patch by
                    728:   assuming that the date of death was just one stepm after the
                    729:   interview.
                    730:   (Repository): Because some people have very long ID (first column)
                    731:   we changed int to long in num[] and we added a new lvector for
                    732:   memory allocation. But we also truncated to 8 characters (left
                    733:   truncation)
                    734:   (Repository): No more line truncation errors.
                    735: 
                    736:   Revision 1.84  2003/06/13 21:44:43  brouard
                    737:   * imach.c (Repository): Replace "freqsummary" at a correct
                    738:   place. It differs from routine "prevalence" which may be called
                    739:   many times. Probs is memory consuming and must be used with
                    740:   parcimony.
                    741:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    742: 
                    743:   Revision 1.83  2003/06/10 13:39:11  lievre
                    744:   *** empty log message ***
                    745: 
                    746:   Revision 1.82  2003/06/05 15:57:20  brouard
                    747:   Add log in  imach.c and  fullversion number is now printed.
                    748: 
                    749: */
                    750: /*
                    751:    Interpolated Markov Chain
                    752: 
                    753:   Short summary of the programme:
                    754:   
1.227     brouard   755:   This program computes Healthy Life Expectancies or State-specific
                    756:   (if states aren't health statuses) Expectancies from
                    757:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    758: 
                    759:   -1- a first survey ("cross") where individuals from different ages
                    760:   are interviewed on their health status or degree of disability (in
                    761:   the case of a health survey which is our main interest)
                    762: 
                    763:   -2- at least a second wave of interviews ("longitudinal") which
                    764:   measure each change (if any) in individual health status.  Health
                    765:   expectancies are computed from the time spent in each health state
                    766:   according to a model. More health states you consider, more time is
                    767:   necessary to reach the Maximum Likelihood of the parameters involved
                    768:   in the model.  The simplest model is the multinomial logistic model
                    769:   where pij is the probability to be observed in state j at the second
                    770:   wave conditional to be observed in state i at the first
                    771:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    772:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    773:   have a more complex model than "constant and age", you should modify
                    774:   the program where the markup *Covariates have to be included here
                    775:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   776:   convergence.
                    777: 
                    778:   The advantage of this computer programme, compared to a simple
                    779:   multinomial logistic model, is clear when the delay between waves is not
                    780:   identical for each individual. Also, if a individual missed an
                    781:   intermediate interview, the information is lost, but taken into
                    782:   account using an interpolation or extrapolation.  
                    783: 
                    784:   hPijx is the probability to be observed in state i at age x+h
                    785:   conditional to the observed state i at age x. The delay 'h' can be
                    786:   split into an exact number (nh*stepm) of unobserved intermediate
                    787:   states. This elementary transition (by month, quarter,
                    788:   semester or year) is modelled as a multinomial logistic.  The hPx
                    789:   matrix is simply the matrix product of nh*stepm elementary matrices
                    790:   and the contribution of each individual to the likelihood is simply
                    791:   hPijx.
                    792: 
                    793:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   794:   of the life expectancies. It also computes the period (stable) prevalence.
                    795: 
                    796: Back prevalence and projections:
1.227     brouard   797: 
                    798:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    799:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    800:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    801:    mobilavproj)
                    802: 
                    803:     Computes the back prevalence limit for any combination of
                    804:     covariate values k at any age between ageminpar and agemaxpar and
                    805:     returns it in **bprlim. In the loops,
                    806: 
                    807:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    808:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    809: 
                    810:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   811:    Computes for any combination of covariates k and any age between bage and fage 
                    812:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    813:                        oldm=oldms;savm=savms;
1.227     brouard   814: 
                    815:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   816:      Computes the transition matrix starting at age 'age' over
                    817:      'nhstepm*hstepm*stepm' months (i.e. until
                    818:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   819:      nhstepm*hstepm matrices. 
                    820: 
                    821:      Returns p3mat[i][j][h] after calling
                    822:      p3mat[i][j][h]=matprod2(newm,
                    823:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    824:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    825:      oldm);
1.226     brouard   826: 
                    827: Important routines
                    828: 
                    829: - func (or funcone), computes logit (pij) distinguishing
                    830:   o fixed variables (single or product dummies or quantitative);
                    831:   o varying variables by:
                    832:    (1) wave (single, product dummies, quantitative), 
                    833:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    834:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    835:        % varying dummy (not done) or quantitative (not done);
                    836: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    837:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    838: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    839:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    840:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   841: 
1.226     brouard   842: 
                    843:   
1.133     brouard   844:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    845:            Institut national d'études démographiques, Paris.
1.126     brouard   846:   This software have been partly granted by Euro-REVES, a concerted action
                    847:   from the European Union.
                    848:   It is copyrighted identically to a GNU software product, ie programme and
                    849:   software can be distributed freely for non commercial use. Latest version
                    850:   can be accessed at http://euroreves.ined.fr/imach .
                    851: 
                    852:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    853:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    854:   
                    855:   **********************************************************************/
                    856: /*
                    857:   main
                    858:   read parameterfile
                    859:   read datafile
                    860:   concatwav
                    861:   freqsummary
                    862:   if (mle >= 1)
                    863:     mlikeli
                    864:   print results files
                    865:   if mle==1 
                    866:      computes hessian
                    867:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    868:       begin-prev-date,...
                    869:   open gnuplot file
                    870:   open html file
1.145     brouard   871:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    872:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    873:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    874:     freexexit2 possible for memory heap.
                    875: 
                    876:   h Pij x                         | pij_nom  ficrestpij
                    877:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    878:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    879:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    880: 
                    881:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    882:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    883:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    884:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    885:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    886: 
1.126     brouard   887:   forecasting if prevfcast==1 prevforecast call prevalence()
                    888:   health expectancies
                    889:   Variance-covariance of DFLE
                    890:   prevalence()
                    891:    movingaverage()
                    892:   varevsij() 
                    893:   if popbased==1 varevsij(,popbased)
                    894:   total life expectancies
                    895:   Variance of period (stable) prevalence
                    896:  end
                    897: */
                    898: 
1.187     brouard   899: /* #define DEBUG */
                    900: /* #define DEBUGBRENT */
1.203     brouard   901: /* #define DEBUGLINMIN */
                    902: /* #define DEBUGHESS */
                    903: #define DEBUGHESSIJ
1.224     brouard   904: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   905: #define POWELL /* Instead of NLOPT */
1.224     brouard   906: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   907: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    908: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   909: 
                    910: #include <math.h>
                    911: #include <stdio.h>
                    912: #include <stdlib.h>
                    913: #include <string.h>
1.226     brouard   914: #include <ctype.h>
1.159     brouard   915: 
                    916: #ifdef _WIN32
                    917: #include <io.h>
1.172     brouard   918: #include <windows.h>
                    919: #include <tchar.h>
1.159     brouard   920: #else
1.126     brouard   921: #include <unistd.h>
1.159     brouard   922: #endif
1.126     brouard   923: 
                    924: #include <limits.h>
                    925: #include <sys/types.h>
1.171     brouard   926: 
                    927: #if defined(__GNUC__)
                    928: #include <sys/utsname.h> /* Doesn't work on Windows */
                    929: #endif
                    930: 
1.126     brouard   931: #include <sys/stat.h>
                    932: #include <errno.h>
1.159     brouard   933: /* extern int errno; */
1.126     brouard   934: 
1.157     brouard   935: /* #ifdef LINUX */
                    936: /* #include <time.h> */
                    937: /* #include "timeval.h" */
                    938: /* #else */
                    939: /* #include <sys/time.h> */
                    940: /* #endif */
                    941: 
1.126     brouard   942: #include <time.h>
                    943: 
1.136     brouard   944: #ifdef GSL
                    945: #include <gsl/gsl_errno.h>
                    946: #include <gsl/gsl_multimin.h>
                    947: #endif
                    948: 
1.167     brouard   949: 
1.162     brouard   950: #ifdef NLOPT
                    951: #include <nlopt.h>
                    952: typedef struct {
                    953:   double (* function)(double [] );
                    954: } myfunc_data ;
                    955: #endif
                    956: 
1.126     brouard   957: /* #include <libintl.h> */
                    958: /* #define _(String) gettext (String) */
                    959: 
1.251     brouard   960: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   961: 
                    962: #define GNUPLOTPROGRAM "gnuplot"
                    963: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    964: #define FILENAMELENGTH 132
                    965: 
                    966: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    967: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    968: 
1.144     brouard   969: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    970: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   971: 
                    972: #define NINTERVMAX 8
1.144     brouard   973: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    974: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    975: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   976: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   977: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    978: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   979: #define MAXN 20000
1.144     brouard   980: #define YEARM 12. /**< Number of months per year */
1.218     brouard   981: /* #define AGESUP 130 */
                    982: #define AGESUP 150
                    983: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   984: #define AGEBASE 40
1.194     brouard   985: #define AGEOVERFLOW 1.e20
1.164     brouard   986: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   987: #ifdef _WIN32
                    988: #define DIRSEPARATOR '\\'
                    989: #define CHARSEPARATOR "\\"
                    990: #define ODIRSEPARATOR '/'
                    991: #else
1.126     brouard   992: #define DIRSEPARATOR '/'
                    993: #define CHARSEPARATOR "/"
                    994: #define ODIRSEPARATOR '\\'
                    995: #endif
                    996: 
1.265   ! brouard   997: /* $Id: imach.c,v 1.264 2017/04/26 06:01:29 brouard Exp $ */
1.126     brouard   998: /* $State: Exp $ */
1.196     brouard   999: #include "version.h"
                   1000: char version[]=__IMACH_VERSION__;
1.224     brouard  1001: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.265   ! brouard  1002: char fullversion[]="$Revision: 1.264 $ $Date: 2017/04/26 06:01:29 $"; 
1.126     brouard  1003: char strstart[80];
                   1004: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1005: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1006: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1007: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1008: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1009: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1010: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1011: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1012: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1013: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1014: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1015: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1016: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1017: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1018: int nsd=0; /**< Total number of single dummy variables (output) */
                   1019: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1020: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1021: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1022: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1023: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1024: int cptcov=0; /* Working variable */
1.218     brouard  1025: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1026: int npar=NPARMAX;
                   1027: int nlstate=2; /* Number of live states */
                   1028: int ndeath=1; /* Number of dead states */
1.130     brouard  1029: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1030: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1031: int popbased=0;
                   1032: 
                   1033: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1034: int maxwav=0; /* Maxim number of waves */
                   1035: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1036: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1037: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1038:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1039: int mle=1, weightopt=0;
1.126     brouard  1040: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1041: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1042: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1043:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1044: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1045: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1046: 
1.130     brouard  1047: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1048: double **matprod2(); /* test */
1.126     brouard  1049: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1050: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1051: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1052: 
1.136     brouard  1053: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1054: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1055: FILE *ficlog, *ficrespow;
1.130     brouard  1056: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1057: double fretone; /* Only one call to likelihood */
1.130     brouard  1058: long ipmx=0; /* Number of contributions */
1.126     brouard  1059: double sw; /* Sum of weights */
                   1060: char filerespow[FILENAMELENGTH];
                   1061: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1062: FILE *ficresilk;
                   1063: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1064: FILE *ficresprobmorprev;
                   1065: FILE *fichtm, *fichtmcov; /* Html File */
                   1066: FILE *ficreseij;
                   1067: char filerese[FILENAMELENGTH];
                   1068: FILE *ficresstdeij;
                   1069: char fileresstde[FILENAMELENGTH];
                   1070: FILE *ficrescveij;
                   1071: char filerescve[FILENAMELENGTH];
                   1072: FILE  *ficresvij;
                   1073: char fileresv[FILENAMELENGTH];
                   1074: FILE  *ficresvpl;
                   1075: char fileresvpl[FILENAMELENGTH];
                   1076: char title[MAXLINE];
1.234     brouard  1077: char model[MAXLINE]; /**< The model line */
1.217     brouard  1078: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1079: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1080: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1081: char command[FILENAMELENGTH];
                   1082: int  outcmd=0;
                   1083: 
1.217     brouard  1084: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1085: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1086: char filelog[FILENAMELENGTH]; /* Log file */
                   1087: char filerest[FILENAMELENGTH];
                   1088: char fileregp[FILENAMELENGTH];
                   1089: char popfile[FILENAMELENGTH];
                   1090: 
                   1091: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1092: 
1.157     brouard  1093: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1094: /* struct timezone tzp; */
                   1095: /* extern int gettimeofday(); */
                   1096: struct tm tml, *gmtime(), *localtime();
                   1097: 
                   1098: extern time_t time();
                   1099: 
                   1100: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1101: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1102: struct tm tm;
                   1103: 
1.126     brouard  1104: char strcurr[80], strfor[80];
                   1105: 
                   1106: char *endptr;
                   1107: long lval;
                   1108: double dval;
                   1109: 
                   1110: #define NR_END 1
                   1111: #define FREE_ARG char*
                   1112: #define FTOL 1.0e-10
                   1113: 
                   1114: #define NRANSI 
1.240     brouard  1115: #define ITMAX 200
                   1116: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1117: 
                   1118: #define TOL 2.0e-4 
                   1119: 
                   1120: #define CGOLD 0.3819660 
                   1121: #define ZEPS 1.0e-10 
                   1122: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1123: 
                   1124: #define GOLD 1.618034 
                   1125: #define GLIMIT 100.0 
                   1126: #define TINY 1.0e-20 
                   1127: 
                   1128: static double maxarg1,maxarg2;
                   1129: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1130: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1131:   
                   1132: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1133: #define rint(a) floor(a+0.5)
1.166     brouard  1134: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1135: #define mytinydouble 1.0e-16
1.166     brouard  1136: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1137: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1138: /* static double dsqrarg; */
                   1139: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1140: static double sqrarg;
                   1141: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1142: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1143: int agegomp= AGEGOMP;
                   1144: 
                   1145: int imx; 
                   1146: int stepm=1;
                   1147: /* Stepm, step in month: minimum step interpolation*/
                   1148: 
                   1149: int estepm;
                   1150: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1151: 
                   1152: int m,nb;
                   1153: long *num;
1.197     brouard  1154: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1155: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1156:                   covariate for which somebody answered excluding 
                   1157:                   undefined. Usually 2: 0 and 1. */
                   1158: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1159:                             covariate for which somebody answered including 
                   1160:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1161: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1162: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1163: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1164: double *ageexmed,*agecens;
                   1165: double dateintmean=0;
                   1166: 
                   1167: double *weight;
                   1168: int **s; /* Status */
1.141     brouard  1169: double *agedc;
1.145     brouard  1170: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1171:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1172:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1173: double **coqvar; /* Fixed quantitative covariate iqv */
                   1174: double ***cotvar; /* Time varying covariate itv */
                   1175: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1176: double  idx; 
                   1177: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1178: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1179: /*k          1  2   3   4     5    6    7     8    9 */
                   1180: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1181: /* Tndvar[k]    1   2   3               4          5 */
                   1182: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1183: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1184: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1185: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1186: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1187: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1188: /* Tprod[i]=k           4               7            */
                   1189: /* Tage[i]=k                  5               8      */
                   1190: /* */
                   1191: /* Type                    */
                   1192: /* V         1  2  3  4  5 */
                   1193: /*           F  F  V  V  V */
                   1194: /*           D  Q  D  D  Q */
                   1195: /*                         */
                   1196: int *TvarsD;
                   1197: int *TvarsDind;
                   1198: int *TvarsQ;
                   1199: int *TvarsQind;
                   1200: 
1.235     brouard  1201: #define MAXRESULTLINES 10
                   1202: int nresult=0;
1.258     brouard  1203: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1204: int TKresult[MAXRESULTLINES];
1.237     brouard  1205: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1206: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1207: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1208: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1209: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1210: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1211: 
1.234     brouard  1212: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1213: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1214: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1215: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1216: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1217: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1218: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1219: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1220: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1221: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1222: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1223: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1224: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1225: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1226: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1227: 
1.230     brouard  1228: int *Tvarsel; /**< Selected covariates for output */
                   1229: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1230: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1231: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1232: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1233: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1234: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1235: int *Tage;
1.227     brouard  1236: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1237: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1238: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1239: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1240: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1241: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1242: int **Tvard;
                   1243: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1244: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1245: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1246:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1247:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1248: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1249: double *lsurv, *lpop, *tpop;
                   1250: 
1.231     brouard  1251: #define FD 1; /* Fixed dummy covariate */
                   1252: #define FQ 2; /* Fixed quantitative covariate */
                   1253: #define FP 3; /* Fixed product covariate */
                   1254: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1255: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1256: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1257: #define VD 10; /* Varying dummy covariate */
                   1258: #define VQ 11; /* Varying quantitative covariate */
                   1259: #define VP 12; /* Varying product covariate */
                   1260: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1261: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1262: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1263: #define APFD 16; /* Age product * fixed dummy covariate */
                   1264: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1265: #define APVD 18; /* Age product * varying dummy covariate */
                   1266: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1267: 
                   1268: #define FTYPE 1; /* Fixed covariate */
                   1269: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1270: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1271: 
                   1272: struct kmodel{
                   1273:        int maintype; /* main type */
                   1274:        int subtype; /* subtype */
                   1275: };
                   1276: struct kmodel modell[NCOVMAX];
                   1277: 
1.143     brouard  1278: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1279: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1280: 
                   1281: /**************** split *************************/
                   1282: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1283: {
                   1284:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1285:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1286:   */ 
                   1287:   char *ss;                            /* pointer */
1.186     brouard  1288:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1289: 
                   1290:   l1 = strlen(path );                  /* length of path */
                   1291:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1292:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1293:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1294:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1295:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1296:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1297:     /* get current working directory */
                   1298:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1299: #ifdef WIN32
                   1300:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1301: #else
                   1302:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1303: #endif
1.126     brouard  1304:       return( GLOCK_ERROR_GETCWD );
                   1305:     }
                   1306:     /* got dirc from getcwd*/
                   1307:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1308:   } else {                             /* strip directory from path */
1.126     brouard  1309:     ss++;                              /* after this, the filename */
                   1310:     l2 = strlen( ss );                 /* length of filename */
                   1311:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1312:     strcpy( name, ss );                /* save file name */
                   1313:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1314:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1315:     printf(" DIRC2 = %s \n",dirc);
                   1316:   }
                   1317:   /* We add a separator at the end of dirc if not exists */
                   1318:   l1 = strlen( dirc );                 /* length of directory */
                   1319:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1320:     dirc[l1] =  DIRSEPARATOR;
                   1321:     dirc[l1+1] = 0; 
                   1322:     printf(" DIRC3 = %s \n",dirc);
                   1323:   }
                   1324:   ss = strrchr( name, '.' );           /* find last / */
                   1325:   if (ss >0){
                   1326:     ss++;
                   1327:     strcpy(ext,ss);                    /* save extension */
                   1328:     l1= strlen( name);
                   1329:     l2= strlen(ss)+1;
                   1330:     strncpy( finame, name, l1-l2);
                   1331:     finame[l1-l2]= 0;
                   1332:   }
                   1333: 
                   1334:   return( 0 );                         /* we're done */
                   1335: }
                   1336: 
                   1337: 
                   1338: /******************************************/
                   1339: 
                   1340: void replace_back_to_slash(char *s, char*t)
                   1341: {
                   1342:   int i;
                   1343:   int lg=0;
                   1344:   i=0;
                   1345:   lg=strlen(t);
                   1346:   for(i=0; i<= lg; i++) {
                   1347:     (s[i] = t[i]);
                   1348:     if (t[i]== '\\') s[i]='/';
                   1349:   }
                   1350: }
                   1351: 
1.132     brouard  1352: char *trimbb(char *out, char *in)
1.137     brouard  1353: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1354:   char *s;
                   1355:   s=out;
                   1356:   while (*in != '\0'){
1.137     brouard  1357:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1358:       in++;
                   1359:     }
                   1360:     *out++ = *in++;
                   1361:   }
                   1362:   *out='\0';
                   1363:   return s;
                   1364: }
                   1365: 
1.187     brouard  1366: /* char *substrchaine(char *out, char *in, char *chain) */
                   1367: /* { */
                   1368: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1369: /*   char *s, *t; */
                   1370: /*   t=in;s=out; */
                   1371: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1372: /*     *out++ = *in++; */
                   1373: /*   } */
                   1374: 
                   1375: /*   /\* *in matches *chain *\/ */
                   1376: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1377: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1378: /*   } */
                   1379: /*   in--; chain--; */
                   1380: /*   while ( (*in != '\0')){ */
                   1381: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1382: /*     *out++ = *in++; */
                   1383: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1384: /*   } */
                   1385: /*   *out='\0'; */
                   1386: /*   out=s; */
                   1387: /*   return out; */
                   1388: /* } */
                   1389: char *substrchaine(char *out, char *in, char *chain)
                   1390: {
                   1391:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1392:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1393: 
                   1394:   char *strloc;
                   1395: 
                   1396:   strcpy (out, in); 
                   1397:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1398:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1399:   if(strloc != NULL){ 
                   1400:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1401:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1402:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1403:   }
                   1404:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1405:   return out;
                   1406: }
                   1407: 
                   1408: 
1.145     brouard  1409: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1410: {
1.187     brouard  1411:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1412:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1413:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1414:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1415:   */
1.160     brouard  1416:   char *s, *t;
1.145     brouard  1417:   t=in;s=in;
                   1418:   while ((*in != occ) && (*in != '\0')){
                   1419:     *alocc++ = *in++;
                   1420:   }
                   1421:   if( *in == occ){
                   1422:     *(alocc)='\0';
                   1423:     s=++in;
                   1424:   }
                   1425:  
                   1426:   if (s == t) {/* occ not found */
                   1427:     *(alocc-(in-s))='\0';
                   1428:     in=s;
                   1429:   }
                   1430:   while ( *in != '\0'){
                   1431:     *blocc++ = *in++;
                   1432:   }
                   1433: 
                   1434:   *blocc='\0';
                   1435:   return t;
                   1436: }
1.137     brouard  1437: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1438: {
1.187     brouard  1439:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1440:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1441:      gives blocc="abcdef2ghi" and alocc="j".
                   1442:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1443:   */
                   1444:   char *s, *t;
                   1445:   t=in;s=in;
                   1446:   while (*in != '\0'){
                   1447:     while( *in == occ){
                   1448:       *blocc++ = *in++;
                   1449:       s=in;
                   1450:     }
                   1451:     *blocc++ = *in++;
                   1452:   }
                   1453:   if (s == t) /* occ not found */
                   1454:     *(blocc-(in-s))='\0';
                   1455:   else
                   1456:     *(blocc-(in-s)-1)='\0';
                   1457:   in=s;
                   1458:   while ( *in != '\0'){
                   1459:     *alocc++ = *in++;
                   1460:   }
                   1461: 
                   1462:   *alocc='\0';
                   1463:   return s;
                   1464: }
                   1465: 
1.126     brouard  1466: int nbocc(char *s, char occ)
                   1467: {
                   1468:   int i,j=0;
                   1469:   int lg=20;
                   1470:   i=0;
                   1471:   lg=strlen(s);
                   1472:   for(i=0; i<= lg; i++) {
1.234     brouard  1473:     if  (s[i] == occ ) j++;
1.126     brouard  1474:   }
                   1475:   return j;
                   1476: }
                   1477: 
1.137     brouard  1478: /* void cutv(char *u,char *v, char*t, char occ) */
                   1479: /* { */
                   1480: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1481: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1482: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1483: /*   int i,lg,j,p=0; */
                   1484: /*   i=0; */
                   1485: /*   lg=strlen(t); */
                   1486: /*   for(j=0; j<=lg-1; j++) { */
                   1487: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1488: /*   } */
1.126     brouard  1489: 
1.137     brouard  1490: /*   for(j=0; j<p; j++) { */
                   1491: /*     (u[j] = t[j]); */
                   1492: /*   } */
                   1493: /*      u[p]='\0'; */
1.126     brouard  1494: 
1.137     brouard  1495: /*    for(j=0; j<= lg; j++) { */
                   1496: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1497: /*   } */
                   1498: /* } */
1.126     brouard  1499: 
1.160     brouard  1500: #ifdef _WIN32
                   1501: char * strsep(char **pp, const char *delim)
                   1502: {
                   1503:   char *p, *q;
                   1504:          
                   1505:   if ((p = *pp) == NULL)
                   1506:     return 0;
                   1507:   if ((q = strpbrk (p, delim)) != NULL)
                   1508:   {
                   1509:     *pp = q + 1;
                   1510:     *q = '\0';
                   1511:   }
                   1512:   else
                   1513:     *pp = 0;
                   1514:   return p;
                   1515: }
                   1516: #endif
                   1517: 
1.126     brouard  1518: /********************** nrerror ********************/
                   1519: 
                   1520: void nrerror(char error_text[])
                   1521: {
                   1522:   fprintf(stderr,"ERREUR ...\n");
                   1523:   fprintf(stderr,"%s\n",error_text);
                   1524:   exit(EXIT_FAILURE);
                   1525: }
                   1526: /*********************** vector *******************/
                   1527: double *vector(int nl, int nh)
                   1528: {
                   1529:   double *v;
                   1530:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1531:   if (!v) nrerror("allocation failure in vector");
                   1532:   return v-nl+NR_END;
                   1533: }
                   1534: 
                   1535: /************************ free vector ******************/
                   1536: void free_vector(double*v, int nl, int nh)
                   1537: {
                   1538:   free((FREE_ARG)(v+nl-NR_END));
                   1539: }
                   1540: 
                   1541: /************************ivector *******************************/
                   1542: int *ivector(long nl,long nh)
                   1543: {
                   1544:   int *v;
                   1545:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1546:   if (!v) nrerror("allocation failure in ivector");
                   1547:   return v-nl+NR_END;
                   1548: }
                   1549: 
                   1550: /******************free ivector **************************/
                   1551: void free_ivector(int *v, long nl, long nh)
                   1552: {
                   1553:   free((FREE_ARG)(v+nl-NR_END));
                   1554: }
                   1555: 
                   1556: /************************lvector *******************************/
                   1557: long *lvector(long nl,long nh)
                   1558: {
                   1559:   long *v;
                   1560:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1561:   if (!v) nrerror("allocation failure in ivector");
                   1562:   return v-nl+NR_END;
                   1563: }
                   1564: 
                   1565: /******************free lvector **************************/
                   1566: void free_lvector(long *v, long nl, long nh)
                   1567: {
                   1568:   free((FREE_ARG)(v+nl-NR_END));
                   1569: }
                   1570: 
                   1571: /******************* imatrix *******************************/
                   1572: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1573:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1574: { 
                   1575:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1576:   int **m; 
                   1577:   
                   1578:   /* allocate pointers to rows */ 
                   1579:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1580:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1581:   m += NR_END; 
                   1582:   m -= nrl; 
                   1583:   
                   1584:   
                   1585:   /* allocate rows and set pointers to them */ 
                   1586:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1587:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1588:   m[nrl] += NR_END; 
                   1589:   m[nrl] -= ncl; 
                   1590:   
                   1591:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1592:   
                   1593:   /* return pointer to array of pointers to rows */ 
                   1594:   return m; 
                   1595: } 
                   1596: 
                   1597: /****************** free_imatrix *************************/
                   1598: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1599:       int **m;
                   1600:       long nch,ncl,nrh,nrl; 
                   1601:      /* free an int matrix allocated by imatrix() */ 
                   1602: { 
                   1603:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1604:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1605: } 
                   1606: 
                   1607: /******************* matrix *******************************/
                   1608: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1609: {
                   1610:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1611:   double **m;
                   1612: 
                   1613:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1614:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1615:   m += NR_END;
                   1616:   m -= nrl;
                   1617: 
                   1618:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1619:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1620:   m[nrl] += NR_END;
                   1621:   m[nrl] -= ncl;
                   1622: 
                   1623:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1624:   return m;
1.145     brouard  1625:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1626: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1627: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1628:    */
                   1629: }
                   1630: 
                   1631: /*************************free matrix ************************/
                   1632: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1633: {
                   1634:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1635:   free((FREE_ARG)(m+nrl-NR_END));
                   1636: }
                   1637: 
                   1638: /******************* ma3x *******************************/
                   1639: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1640: {
                   1641:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1642:   double ***m;
                   1643: 
                   1644:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1645:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1646:   m += NR_END;
                   1647:   m -= nrl;
                   1648: 
                   1649:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1650:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1651:   m[nrl] += NR_END;
                   1652:   m[nrl] -= ncl;
                   1653: 
                   1654:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1655: 
                   1656:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1657:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1658:   m[nrl][ncl] += NR_END;
                   1659:   m[nrl][ncl] -= nll;
                   1660:   for (j=ncl+1; j<=nch; j++) 
                   1661:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1662:   
                   1663:   for (i=nrl+1; i<=nrh; i++) {
                   1664:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1665:     for (j=ncl+1; j<=nch; j++) 
                   1666:       m[i][j]=m[i][j-1]+nlay;
                   1667:   }
                   1668:   return m; 
                   1669:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1670:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1671:   */
                   1672: }
                   1673: 
                   1674: /*************************free ma3x ************************/
                   1675: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1676: {
                   1677:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1678:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1679:   free((FREE_ARG)(m+nrl-NR_END));
                   1680: }
                   1681: 
                   1682: /*************** function subdirf ***********/
                   1683: char *subdirf(char fileres[])
                   1684: {
                   1685:   /* Caution optionfilefiname is hidden */
                   1686:   strcpy(tmpout,optionfilefiname);
                   1687:   strcat(tmpout,"/"); /* Add to the right */
                   1688:   strcat(tmpout,fileres);
                   1689:   return tmpout;
                   1690: }
                   1691: 
                   1692: /*************** function subdirf2 ***********/
                   1693: char *subdirf2(char fileres[], char *preop)
                   1694: {
                   1695:   
                   1696:   /* Caution optionfilefiname is hidden */
                   1697:   strcpy(tmpout,optionfilefiname);
                   1698:   strcat(tmpout,"/");
                   1699:   strcat(tmpout,preop);
                   1700:   strcat(tmpout,fileres);
                   1701:   return tmpout;
                   1702: }
                   1703: 
                   1704: /*************** function subdirf3 ***********/
                   1705: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1706: {
                   1707:   
                   1708:   /* Caution optionfilefiname is hidden */
                   1709:   strcpy(tmpout,optionfilefiname);
                   1710:   strcat(tmpout,"/");
                   1711:   strcat(tmpout,preop);
                   1712:   strcat(tmpout,preop2);
                   1713:   strcat(tmpout,fileres);
                   1714:   return tmpout;
                   1715: }
1.213     brouard  1716:  
                   1717: /*************** function subdirfext ***********/
                   1718: char *subdirfext(char fileres[], char *preop, char *postop)
                   1719: {
                   1720:   
                   1721:   strcpy(tmpout,preop);
                   1722:   strcat(tmpout,fileres);
                   1723:   strcat(tmpout,postop);
                   1724:   return tmpout;
                   1725: }
1.126     brouard  1726: 
1.213     brouard  1727: /*************** function subdirfext3 ***********/
                   1728: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1729: {
                   1730:   
                   1731:   /* Caution optionfilefiname is hidden */
                   1732:   strcpy(tmpout,optionfilefiname);
                   1733:   strcat(tmpout,"/");
                   1734:   strcat(tmpout,preop);
                   1735:   strcat(tmpout,fileres);
                   1736:   strcat(tmpout,postop);
                   1737:   return tmpout;
                   1738: }
                   1739:  
1.162     brouard  1740: char *asc_diff_time(long time_sec, char ascdiff[])
                   1741: {
                   1742:   long sec_left, days, hours, minutes;
                   1743:   days = (time_sec) / (60*60*24);
                   1744:   sec_left = (time_sec) % (60*60*24);
                   1745:   hours = (sec_left) / (60*60) ;
                   1746:   sec_left = (sec_left) %(60*60);
                   1747:   minutes = (sec_left) /60;
                   1748:   sec_left = (sec_left) % (60);
                   1749:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1750:   return ascdiff;
                   1751: }
                   1752: 
1.126     brouard  1753: /***************** f1dim *************************/
                   1754: extern int ncom; 
                   1755: extern double *pcom,*xicom;
                   1756: extern double (*nrfunc)(double []); 
                   1757:  
                   1758: double f1dim(double x) 
                   1759: { 
                   1760:   int j; 
                   1761:   double f;
                   1762:   double *xt; 
                   1763:  
                   1764:   xt=vector(1,ncom); 
                   1765:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1766:   f=(*nrfunc)(xt); 
                   1767:   free_vector(xt,1,ncom); 
                   1768:   return f; 
                   1769: } 
                   1770: 
                   1771: /*****************brent *************************/
                   1772: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1773: {
                   1774:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1775:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1776:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1777:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1778:    * returned function value. 
                   1779:   */
1.126     brouard  1780:   int iter; 
                   1781:   double a,b,d,etemp;
1.159     brouard  1782:   double fu=0,fv,fw,fx;
1.164     brouard  1783:   double ftemp=0.;
1.126     brouard  1784:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1785:   double e=0.0; 
                   1786:  
                   1787:   a=(ax < cx ? ax : cx); 
                   1788:   b=(ax > cx ? ax : cx); 
                   1789:   x=w=v=bx; 
                   1790:   fw=fv=fx=(*f)(x); 
                   1791:   for (iter=1;iter<=ITMAX;iter++) { 
                   1792:     xm=0.5*(a+b); 
                   1793:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1794:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1795:     printf(".");fflush(stdout);
                   1796:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1797: #ifdef DEBUGBRENT
1.126     brouard  1798:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1799:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1800:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1801: #endif
                   1802:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1803:       *xmin=x; 
                   1804:       return fx; 
                   1805:     } 
                   1806:     ftemp=fu;
                   1807:     if (fabs(e) > tol1) { 
                   1808:       r=(x-w)*(fx-fv); 
                   1809:       q=(x-v)*(fx-fw); 
                   1810:       p=(x-v)*q-(x-w)*r; 
                   1811:       q=2.0*(q-r); 
                   1812:       if (q > 0.0) p = -p; 
                   1813:       q=fabs(q); 
                   1814:       etemp=e; 
                   1815:       e=d; 
                   1816:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1817:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1818:       else { 
1.224     brouard  1819:                                d=p/q; 
                   1820:                                u=x+d; 
                   1821:                                if (u-a < tol2 || b-u < tol2) 
                   1822:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1823:       } 
                   1824:     } else { 
                   1825:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1826:     } 
                   1827:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1828:     fu=(*f)(u); 
                   1829:     if (fu <= fx) { 
                   1830:       if (u >= x) a=x; else b=x; 
                   1831:       SHFT(v,w,x,u) 
1.183     brouard  1832:       SHFT(fv,fw,fx,fu) 
                   1833:     } else { 
                   1834:       if (u < x) a=u; else b=u; 
                   1835:       if (fu <= fw || w == x) { 
1.224     brouard  1836:                                v=w; 
                   1837:                                w=u; 
                   1838:                                fv=fw; 
                   1839:                                fw=fu; 
1.183     brouard  1840:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1841:                                v=u; 
                   1842:                                fv=fu; 
1.183     brouard  1843:       } 
                   1844:     } 
1.126     brouard  1845:   } 
                   1846:   nrerror("Too many iterations in brent"); 
                   1847:   *xmin=x; 
                   1848:   return fx; 
                   1849: } 
                   1850: 
                   1851: /****************** mnbrak ***********************/
                   1852: 
                   1853: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1854:            double (*func)(double)) 
1.183     brouard  1855: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1856: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1857: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1858: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1859:    */
1.126     brouard  1860:   double ulim,u,r,q, dum;
                   1861:   double fu; 
1.187     brouard  1862: 
                   1863:   double scale=10.;
                   1864:   int iterscale=0;
                   1865: 
                   1866:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1867:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1868: 
                   1869: 
                   1870:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1871:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1872:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1873:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1874:   /* } */
                   1875: 
1.126     brouard  1876:   if (*fb > *fa) { 
                   1877:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1878:     SHFT(dum,*fb,*fa,dum) 
                   1879:   } 
1.126     brouard  1880:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1881:   *fc=(*func)(*cx); 
1.183     brouard  1882: #ifdef DEBUG
1.224     brouard  1883:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1884:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1885: #endif
1.224     brouard  1886:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1887:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1888:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1889:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1890:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1891:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1892:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1893:       fu=(*func)(u); 
1.163     brouard  1894: #ifdef DEBUG
                   1895:       /* f(x)=A(x-u)**2+f(u) */
                   1896:       double A, fparabu; 
                   1897:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1898:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1899:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1900:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1901:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1902:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1903:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1904:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1905: #endif 
1.184     brouard  1906: #ifdef MNBRAKORIGINAL
1.183     brouard  1907: #else
1.191     brouard  1908: /*       if (fu > *fc) { */
                   1909: /* #ifdef DEBUG */
                   1910: /*       printf("mnbrak4  fu > fc \n"); */
                   1911: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1912: /* #endif */
                   1913: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1914: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1915: /*     dum=u; /\* Shifting c and u *\/ */
                   1916: /*     u = *cx; */
                   1917: /*     *cx = dum; */
                   1918: /*     dum = fu; */
                   1919: /*     fu = *fc; */
                   1920: /*     *fc =dum; */
                   1921: /*       } else { /\* end *\/ */
                   1922: /* #ifdef DEBUG */
                   1923: /*       printf("mnbrak3  fu < fc \n"); */
                   1924: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1925: /* #endif */
                   1926: /*     dum=u; /\* Shifting c and u *\/ */
                   1927: /*     u = *cx; */
                   1928: /*     *cx = dum; */
                   1929: /*     dum = fu; */
                   1930: /*     fu = *fc; */
                   1931: /*     *fc =dum; */
                   1932: /*       } */
1.224     brouard  1933: #ifdef DEBUGMNBRAK
                   1934:                 double A, fparabu; 
                   1935:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1936:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1937:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1938:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1939: #endif
1.191     brouard  1940:       dum=u; /* Shifting c and u */
                   1941:       u = *cx;
                   1942:       *cx = dum;
                   1943:       dum = fu;
                   1944:       fu = *fc;
                   1945:       *fc =dum;
1.183     brouard  1946: #endif
1.162     brouard  1947:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1948: #ifdef DEBUG
1.224     brouard  1949:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1950:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1951: #endif
1.126     brouard  1952:       fu=(*func)(u); 
                   1953:       if (fu < *fc) { 
1.183     brouard  1954: #ifdef DEBUG
1.224     brouard  1955:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1956:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1957: #endif
                   1958:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1959:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1960: #ifdef DEBUG
                   1961:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1962: #endif
                   1963:       } 
1.162     brouard  1964:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1965: #ifdef DEBUG
1.224     brouard  1966:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1967:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1968: #endif
1.126     brouard  1969:       u=ulim; 
                   1970:       fu=(*func)(u); 
1.183     brouard  1971:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1972: #ifdef DEBUG
1.224     brouard  1973:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1974:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1975: #endif
1.126     brouard  1976:       u=(*cx)+GOLD*(*cx-*bx); 
                   1977:       fu=(*func)(u); 
1.224     brouard  1978: #ifdef DEBUG
                   1979:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1980:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1981: #endif
1.183     brouard  1982:     } /* end tests */
1.126     brouard  1983:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1984:     SHFT(*fa,*fb,*fc,fu) 
                   1985: #ifdef DEBUG
1.224     brouard  1986:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1987:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1988: #endif
                   1989:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1990: } 
                   1991: 
                   1992: /*************** linmin ************************/
1.162     brouard  1993: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1994: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1995: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1996: the value of func at the returned location p . This is actually all accomplished by calling the
                   1997: routines mnbrak and brent .*/
1.126     brouard  1998: int ncom; 
                   1999: double *pcom,*xicom;
                   2000: double (*nrfunc)(double []); 
                   2001:  
1.224     brouard  2002: #ifdef LINMINORIGINAL
1.126     brouard  2003: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2004: #else
                   2005: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2006: #endif
1.126     brouard  2007: { 
                   2008:   double brent(double ax, double bx, double cx, 
                   2009:               double (*f)(double), double tol, double *xmin); 
                   2010:   double f1dim(double x); 
                   2011:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2012:              double *fc, double (*func)(double)); 
                   2013:   int j; 
                   2014:   double xx,xmin,bx,ax; 
                   2015:   double fx,fb,fa;
1.187     brouard  2016: 
1.203     brouard  2017: #ifdef LINMINORIGINAL
                   2018: #else
                   2019:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2020: #endif
                   2021:   
1.126     brouard  2022:   ncom=n; 
                   2023:   pcom=vector(1,n); 
                   2024:   xicom=vector(1,n); 
                   2025:   nrfunc=func; 
                   2026:   for (j=1;j<=n;j++) { 
                   2027:     pcom[j]=p[j]; 
1.202     brouard  2028:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2029:   } 
1.187     brouard  2030: 
1.203     brouard  2031: #ifdef LINMINORIGINAL
                   2032:   xx=1.;
                   2033: #else
                   2034:   axs=0.0;
                   2035:   xxs=1.;
                   2036:   do{
                   2037:     xx= xxs;
                   2038: #endif
1.187     brouard  2039:     ax=0.;
                   2040:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2041:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2042:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2043:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2044:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2045:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2046:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2047: #ifdef LINMINORIGINAL
                   2048: #else
                   2049:     if (fx != fx){
1.224     brouard  2050:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2051:                        printf("|");
                   2052:                        fprintf(ficlog,"|");
1.203     brouard  2053: #ifdef DEBUGLINMIN
1.224     brouard  2054:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2055: #endif
                   2056:     }
1.224     brouard  2057:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2058: #endif
                   2059:   
1.191     brouard  2060: #ifdef DEBUGLINMIN
                   2061:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2062:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2063: #endif
1.224     brouard  2064: #ifdef LINMINORIGINAL
                   2065: #else
                   2066:        if(fb == fx){ /* Flat function in the direction */
                   2067:                xmin=xx;
                   2068:     *flat=1;
                   2069:        }else{
                   2070:     *flat=0;
                   2071: #endif
                   2072:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2073:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2074:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2075:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2076:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2077:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2078: #ifdef DEBUG
1.224     brouard  2079:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2080:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2081: #endif
                   2082: #ifdef LINMINORIGINAL
                   2083: #else
                   2084:                        }
1.126     brouard  2085: #endif
1.191     brouard  2086: #ifdef DEBUGLINMIN
                   2087:   printf("linmin end ");
1.202     brouard  2088:   fprintf(ficlog,"linmin end ");
1.191     brouard  2089: #endif
1.126     brouard  2090:   for (j=1;j<=n;j++) { 
1.203     brouard  2091: #ifdef LINMINORIGINAL
                   2092:     xi[j] *= xmin; 
                   2093: #else
                   2094: #ifdef DEBUGLINMIN
                   2095:     if(xxs <1.0)
                   2096:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2097: #endif
                   2098:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2099: #ifdef DEBUGLINMIN
                   2100:     if(xxs <1.0)
                   2101:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2102: #endif
                   2103: #endif
1.187     brouard  2104:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2105:   } 
1.191     brouard  2106: #ifdef DEBUGLINMIN
1.203     brouard  2107:   printf("\n");
1.191     brouard  2108:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2109:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2110:   for (j=1;j<=n;j++) { 
1.202     brouard  2111:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2112:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2113:     if(j % ncovmodel == 0){
1.191     brouard  2114:       printf("\n");
1.202     brouard  2115:       fprintf(ficlog,"\n");
                   2116:     }
1.191     brouard  2117:   }
1.203     brouard  2118: #else
1.191     brouard  2119: #endif
1.126     brouard  2120:   free_vector(xicom,1,n); 
                   2121:   free_vector(pcom,1,n); 
                   2122: } 
                   2123: 
                   2124: 
                   2125: /*************** powell ************************/
1.162     brouard  2126: /*
                   2127: Minimization of a function func of n variables. Input consists of an initial starting point
                   2128: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2129: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2130: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2131: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2132: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2133:  */
1.224     brouard  2134: #ifdef LINMINORIGINAL
                   2135: #else
                   2136:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2137:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2138: #endif
1.126     brouard  2139: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2140:            double (*func)(double [])) 
                   2141: { 
1.224     brouard  2142: #ifdef LINMINORIGINAL
                   2143:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2144:              double (*func)(double [])); 
1.224     brouard  2145: #else 
1.241     brouard  2146:  void linmin(double p[], double xi[], int n, double *fret,
                   2147:             double (*func)(double []),int *flat); 
1.224     brouard  2148: #endif
1.239     brouard  2149:  int i,ibig,j,jk,k; 
1.126     brouard  2150:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2151:   double directest;
1.126     brouard  2152:   double fp,fptt;
                   2153:   double *xits;
                   2154:   int niterf, itmp;
1.224     brouard  2155: #ifdef LINMINORIGINAL
                   2156: #else
                   2157: 
                   2158:   flatdir=ivector(1,n); 
                   2159:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2160: #endif
1.126     brouard  2161: 
                   2162:   pt=vector(1,n); 
                   2163:   ptt=vector(1,n); 
                   2164:   xit=vector(1,n); 
                   2165:   xits=vector(1,n); 
                   2166:   *fret=(*func)(p); 
                   2167:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2168:   rcurr_time = time(NULL);  
1.126     brouard  2169:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2170:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2171:     ibig=0; 
                   2172:     del=0.0; 
1.157     brouard  2173:     rlast_time=rcurr_time;
                   2174:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2175:     rcurr_time = time(NULL);  
                   2176:     curr_time = *localtime(&rcurr_time);
                   2177:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2178:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2179: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2180:     for (i=1;i<=n;i++) {
1.126     brouard  2181:       fprintf(ficrespow," %.12lf", p[i]);
                   2182:     }
1.239     brouard  2183:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2184:     printf("\n#model=  1      +     age ");
                   2185:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2186:     if(nagesqr==1){
1.241     brouard  2187:        printf("  + age*age  ");
                   2188:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2189:     }
                   2190:     for(j=1;j <=ncovmodel-2;j++){
                   2191:       if(Typevar[j]==0) {
                   2192:        printf("  +      V%d  ",Tvar[j]);
                   2193:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2194:       }else if(Typevar[j]==1) {
                   2195:        printf("  +    V%d*age ",Tvar[j]);
                   2196:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2197:       }else if(Typevar[j]==2) {
                   2198:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2199:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2200:       }
                   2201:     }
1.126     brouard  2202:     printf("\n");
1.239     brouard  2203: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2204: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2205:     fprintf(ficlog,"\n");
1.239     brouard  2206:     for(i=1,jk=1; i <=nlstate; i++){
                   2207:       for(k=1; k <=(nlstate+ndeath); k++){
                   2208:        if (k != i) {
                   2209:          printf("%d%d ",i,k);
                   2210:          fprintf(ficlog,"%d%d ",i,k);
                   2211:          for(j=1; j <=ncovmodel; j++){
                   2212:            printf("%12.7f ",p[jk]);
                   2213:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2214:            jk++; 
                   2215:          }
                   2216:          printf("\n");
                   2217:          fprintf(ficlog,"\n");
                   2218:        }
                   2219:       }
                   2220:     }
1.241     brouard  2221:     if(*iter <=3 && *iter >1){
1.157     brouard  2222:       tml = *localtime(&rcurr_time);
                   2223:       strcpy(strcurr,asctime(&tml));
                   2224:       rforecast_time=rcurr_time; 
1.126     brouard  2225:       itmp = strlen(strcurr);
                   2226:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2227:        strcurr[itmp-1]='\0';
1.162     brouard  2228:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2229:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2230:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2231:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2232:        forecast_time = *localtime(&rforecast_time);
                   2233:        strcpy(strfor,asctime(&forecast_time));
                   2234:        itmp = strlen(strfor);
                   2235:        if(strfor[itmp-1]=='\n')
                   2236:          strfor[itmp-1]='\0';
                   2237:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2238:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2239:       }
                   2240:     }
1.187     brouard  2241:     for (i=1;i<=n;i++) { /* For each direction i */
                   2242:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2243:       fptt=(*fret); 
                   2244: #ifdef DEBUG
1.203     brouard  2245:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2246:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2247: #endif
1.203     brouard  2248:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2249:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2250: #ifdef LINMINORIGINAL
1.188     brouard  2251:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2252: #else
                   2253:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2254:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2255: #endif
                   2256:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2257:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2258:                                /* because that direction will be replaced unless the gain del is small */
                   2259:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2260:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2261:                                /* with the new direction. */
                   2262:                                del=fabs(fptt-(*fret)); 
                   2263:                                ibig=i; 
1.126     brouard  2264:       } 
                   2265: #ifdef DEBUG
                   2266:       printf("%d %.12e",i,(*fret));
                   2267:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2268:       for (j=1;j<=n;j++) {
1.224     brouard  2269:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2270:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2271:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2272:       }
                   2273:       for(j=1;j<=n;j++) {
1.225     brouard  2274:                                printf(" p(%d)=%.12e",j,p[j]);
                   2275:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2276:       }
                   2277:       printf("\n");
                   2278:       fprintf(ficlog,"\n");
                   2279: #endif
1.187     brouard  2280:     } /* end loop on each direction i */
                   2281:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2282:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2283:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2284:       for(j=1;j<=n;j++) {
1.225     brouard  2285:                                if(flatdir[j] >0){
                   2286:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2287:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2288:                                }
                   2289:                                /* printf("\n"); */
                   2290:                                /* fprintf(ficlog,"\n"); */
                   2291:                        }
1.243     brouard  2292:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2293:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2294:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2295:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2296:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2297:       /* decreased of more than 3.84  */
                   2298:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2299:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2300:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2301:                        
1.188     brouard  2302:       /* Starting the program with initial values given by a former maximization will simply change */
                   2303:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2304:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2305:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2306: #ifdef DEBUG
                   2307:       int k[2],l;
                   2308:       k[0]=1;
                   2309:       k[1]=-1;
                   2310:       printf("Max: %.12e",(*func)(p));
                   2311:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2312:       for (j=1;j<=n;j++) {
                   2313:        printf(" %.12e",p[j]);
                   2314:        fprintf(ficlog," %.12e",p[j]);
                   2315:       }
                   2316:       printf("\n");
                   2317:       fprintf(ficlog,"\n");
                   2318:       for(l=0;l<=1;l++) {
                   2319:        for (j=1;j<=n;j++) {
                   2320:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2321:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2322:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2323:        }
                   2324:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2325:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2326:       }
                   2327: #endif
                   2328: 
1.224     brouard  2329: #ifdef LINMINORIGINAL
                   2330: #else
                   2331:       free_ivector(flatdir,1,n); 
                   2332: #endif
1.126     brouard  2333:       free_vector(xit,1,n); 
                   2334:       free_vector(xits,1,n); 
                   2335:       free_vector(ptt,1,n); 
                   2336:       free_vector(pt,1,n); 
                   2337:       return; 
1.192     brouard  2338:     } /* enough precision */ 
1.240     brouard  2339:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2340:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2341:       ptt[j]=2.0*p[j]-pt[j]; 
                   2342:       xit[j]=p[j]-pt[j]; 
                   2343:       pt[j]=p[j]; 
                   2344:     } 
1.181     brouard  2345:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2346: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2347:                if (*iter <=4) {
1.225     brouard  2348: #else
                   2349: #endif
1.224     brouard  2350: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2351: #else
1.161     brouard  2352:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2353: #endif
1.162     brouard  2354:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2355:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2356:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2357:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2358:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2359:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2360:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2361:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2362:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2363:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2364:       /* mu² and del² are equal when f3=f1 */
                   2365:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2366:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2367:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2368:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2369: #ifdef NRCORIGINAL
                   2370:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2371: #else
                   2372:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2373:       t= t- del*SQR(fp-fptt);
1.183     brouard  2374: #endif
1.202     brouard  2375:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2376: #ifdef DEBUG
1.181     brouard  2377:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2378:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2379:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2380:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2381:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2382:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2383:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2384:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2385: #endif
1.183     brouard  2386: #ifdef POWELLORIGINAL
                   2387:       if (t < 0.0) { /* Then we use it for new direction */
                   2388: #else
1.182     brouard  2389:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2390:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2391:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2392:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2393:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2394:       } 
1.181     brouard  2395:       if (directest < 0.0) { /* Then we use it for new direction */
                   2396: #endif
1.191     brouard  2397: #ifdef DEBUGLINMIN
1.234     brouard  2398:        printf("Before linmin in direction P%d-P0\n",n);
                   2399:        for (j=1;j<=n;j++) {
                   2400:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2401:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2402:          if(j % ncovmodel == 0){
                   2403:            printf("\n");
                   2404:            fprintf(ficlog,"\n");
                   2405:          }
                   2406:        }
1.224     brouard  2407: #endif
                   2408: #ifdef LINMINORIGINAL
1.234     brouard  2409:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2410: #else
1.234     brouard  2411:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2412:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2413: #endif
1.234     brouard  2414:        
1.191     brouard  2415: #ifdef DEBUGLINMIN
1.234     brouard  2416:        for (j=1;j<=n;j++) { 
                   2417:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2418:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2419:          if(j % ncovmodel == 0){
                   2420:            printf("\n");
                   2421:            fprintf(ficlog,"\n");
                   2422:          }
                   2423:        }
1.224     brouard  2424: #endif
1.234     brouard  2425:        for (j=1;j<=n;j++) { 
                   2426:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2427:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2428:        }
1.224     brouard  2429: #ifdef LINMINORIGINAL
                   2430: #else
1.234     brouard  2431:        for (j=1, flatd=0;j<=n;j++) {
                   2432:          if(flatdir[j]>0)
                   2433:            flatd++;
                   2434:        }
                   2435:        if(flatd >0){
1.255     brouard  2436:          printf("%d flat directions: ",flatd);
                   2437:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2438:          for (j=1;j<=n;j++) { 
                   2439:            if(flatdir[j]>0){
                   2440:              printf("%d ",j);
                   2441:              fprintf(ficlog,"%d ",j);
                   2442:            }
                   2443:          }
                   2444:          printf("\n");
                   2445:          fprintf(ficlog,"\n");
                   2446:        }
1.191     brouard  2447: #endif
1.234     brouard  2448:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2449:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2450:        
1.126     brouard  2451: #ifdef DEBUG
1.234     brouard  2452:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2453:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2454:        for(j=1;j<=n;j++){
                   2455:          printf(" %lf",xit[j]);
                   2456:          fprintf(ficlog," %lf",xit[j]);
                   2457:        }
                   2458:        printf("\n");
                   2459:        fprintf(ficlog,"\n");
1.126     brouard  2460: #endif
1.192     brouard  2461:       } /* end of t or directest negative */
1.224     brouard  2462: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2463: #else
1.234     brouard  2464:       } /* end if (fptt < fp)  */
1.192     brouard  2465: #endif
1.225     brouard  2466: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2467:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2468: #else
1.224     brouard  2469: #endif
1.234     brouard  2470:                } /* loop iteration */ 
1.126     brouard  2471: } 
1.234     brouard  2472:   
1.126     brouard  2473: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2474:   
1.235     brouard  2475:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2476:   {
1.235     brouard  2477:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2478:        (and selected quantitative values in nres)
                   2479:        by left multiplying the unit
1.234     brouard  2480:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2481:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2482:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2483:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2484:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2485:   /* Initial matrix pimij */
                   2486:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2487:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2488:   /*  0,                   0                  , 1} */
                   2489:   /*
                   2490:    * and after some iteration: */
                   2491:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2492:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2493:   /*  0,                   0                  , 1} */
                   2494:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2495:   /* {0.51571254859325999, 0.4842874514067399, */
                   2496:   /*  0.51326036147820708, 0.48673963852179264} */
                   2497:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2498:     
1.126     brouard  2499:   int i, ii,j,k;
1.209     brouard  2500:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2501:   /* double **matprod2(); */ /* test */
1.218     brouard  2502:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2503:   double **newm;
1.209     brouard  2504:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2505:   int ncvloop=0;
1.169     brouard  2506:   
1.209     brouard  2507:   min=vector(1,nlstate);
                   2508:   max=vector(1,nlstate);
                   2509:   meandiff=vector(1,nlstate);
                   2510: 
1.218     brouard  2511:        /* Starting with matrix unity */
1.126     brouard  2512:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2513:     for (j=1;j<=nlstate+ndeath;j++){
                   2514:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2515:     }
1.169     brouard  2516:   
                   2517:   cov[1]=1.;
                   2518:   
                   2519:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2520:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2521:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2522:     ncvloop++;
1.126     brouard  2523:     newm=savm;
                   2524:     /* Covariates have to be included here again */
1.138     brouard  2525:     cov[2]=agefin;
1.187     brouard  2526:     if(nagesqr==1)
                   2527:       cov[3]= agefin*agefin;;
1.234     brouard  2528:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2529:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2530:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2531:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2532:     }
                   2533:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2534:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2535:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2536:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2537:     }
1.237     brouard  2538:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2539:       if(Dummy[Tvar[Tage[k]]]){
                   2540:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2541:       } else{
1.235     brouard  2542:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2543:       }
1.235     brouard  2544:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2545:     }
1.237     brouard  2546:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2547:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2548:       if(Dummy[Tvard[k][1]==0]){
                   2549:        if(Dummy[Tvard[k][2]==0]){
                   2550:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2551:        }else{
                   2552:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2553:        }
                   2554:       }else{
                   2555:        if(Dummy[Tvard[k][2]==0]){
                   2556:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2557:        }else{
                   2558:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2559:        }
                   2560:       }
1.234     brouard  2561:     }
1.138     brouard  2562:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2563:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2564:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2565:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2566:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2567:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2568:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2569:     
1.126     brouard  2570:     savm=oldm;
                   2571:     oldm=newm;
1.209     brouard  2572: 
                   2573:     for(j=1; j<=nlstate; j++){
                   2574:       max[j]=0.;
                   2575:       min[j]=1.;
                   2576:     }
                   2577:     for(i=1;i<=nlstate;i++){
                   2578:       sumnew=0;
                   2579:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2580:       for(j=1; j<=nlstate; j++){ 
                   2581:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2582:        max[j]=FMAX(max[j],prlim[i][j]);
                   2583:        min[j]=FMIN(min[j],prlim[i][j]);
                   2584:       }
                   2585:     }
                   2586: 
1.126     brouard  2587:     maxmax=0.;
1.209     brouard  2588:     for(j=1; j<=nlstate; j++){
                   2589:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2590:       maxmax=FMAX(maxmax,meandiff[j]);
                   2591:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2592:     } /* j loop */
1.203     brouard  2593:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2594:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2595:     if(maxmax < ftolpl){
1.209     brouard  2596:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2597:       free_vector(min,1,nlstate);
                   2598:       free_vector(max,1,nlstate);
                   2599:       free_vector(meandiff,1,nlstate);
1.126     brouard  2600:       return prlim;
                   2601:     }
1.169     brouard  2602:   } /* age loop */
1.208     brouard  2603:     /* After some age loop it doesn't converge */
1.209     brouard  2604:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2605: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2606:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2607:   free_vector(min,1,nlstate);
                   2608:   free_vector(max,1,nlstate);
                   2609:   free_vector(meandiff,1,nlstate);
1.208     brouard  2610:   
1.169     brouard  2611:   return prlim; /* should not reach here */
1.126     brouard  2612: }
                   2613: 
1.217     brouard  2614: 
                   2615:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2616: 
1.218     brouard  2617:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2618:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2619:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2620: {
1.264     brouard  2621:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2622:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2623:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2624:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2625:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2626:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2627:   /* Initial matrix pimij */
                   2628:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2629:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2630:   /*  0,                   0                  , 1} */
                   2631:   /*
                   2632:    * and after some iteration: */
                   2633:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2634:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2635:   /*  0,                   0                  , 1} */
                   2636:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2637:   /* {0.51571254859325999, 0.4842874514067399, */
                   2638:   /*  0.51326036147820708, 0.48673963852179264} */
                   2639:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2640: 
                   2641:   int i, ii,j,k;
1.247     brouard  2642:   int first=0;
1.217     brouard  2643:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2644:   /* double **matprod2(); */ /* test */
                   2645:   double **out, cov[NCOVMAX+1], **bmij();
                   2646:   double **newm;
1.218     brouard  2647:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2648:   double        **oldm, **savm;  /* for use */
                   2649: 
1.217     brouard  2650:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2651:   int ncvloop=0;
                   2652:   
                   2653:   min=vector(1,nlstate);
                   2654:   max=vector(1,nlstate);
                   2655:   meandiff=vector(1,nlstate);
                   2656: 
1.218     brouard  2657:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2658:        oldm=oldms; savm=savms;
                   2659: 
                   2660:        /* Starting with matrix unity */
                   2661:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2662:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2663:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2664:     }
                   2665:   
                   2666:   cov[1]=1.;
                   2667:   
                   2668:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2669:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2670:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2671:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2672:     ncvloop++;
1.218     brouard  2673:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2674:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2675:     /* Covariates have to be included here again */
                   2676:     cov[2]=agefin;
                   2677:     if(nagesqr==1)
                   2678:       cov[3]= agefin*agefin;;
1.242     brouard  2679:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2680:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2681:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2682:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2683:     }
                   2684:     /* for (k=1; k<=cptcovn;k++) { */
                   2685:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2686:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2687:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2688:     /* } */
                   2689:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2690:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2691:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2692:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2693:     }
                   2694:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2695:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2696:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2697:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2698:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2699:       if(Dummy[Tvar[Tage[k]]]){
                   2700:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2701:       } else{
                   2702:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2703:       }
                   2704:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2705:     }
                   2706:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2707:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2708:       if(Dummy[Tvard[k][1]==0]){
                   2709:        if(Dummy[Tvard[k][2]==0]){
                   2710:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2711:        }else{
                   2712:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2713:        }
                   2714:       }else{
                   2715:        if(Dummy[Tvard[k][2]==0]){
                   2716:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2717:        }else{
                   2718:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2719:        }
                   2720:       }
1.217     brouard  2721:     }
                   2722:     
                   2723:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2724:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2725:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2726:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2727:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2728:                /* ij should be linked to the correct index of cov */
                   2729:                /* age and covariate values ij are in 'cov', but we need to pass
                   2730:                 * ij for the observed prevalence at age and status and covariate
                   2731:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2732:                 */
                   2733:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2734:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2735:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2736:     savm=oldm;
                   2737:     oldm=newm;
                   2738:     for(j=1; j<=nlstate; j++){
                   2739:       max[j]=0.;
                   2740:       min[j]=1.;
                   2741:     }
                   2742:     for(j=1; j<=nlstate; j++){ 
                   2743:       for(i=1;i<=nlstate;i++){
1.234     brouard  2744:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2745:        bprlim[i][j]= newm[i][j];
                   2746:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2747:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2748:       }
                   2749:     }
1.218     brouard  2750:                
1.217     brouard  2751:     maxmax=0.;
                   2752:     for(i=1; i<=nlstate; i++){
                   2753:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2754:       maxmax=FMAX(maxmax,meandiff[i]);
                   2755:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2756:     } /* j loop */
                   2757:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2758:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2759:     if(maxmax < ftolpl){
1.220     brouard  2760:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2761:       free_vector(min,1,nlstate);
                   2762:       free_vector(max,1,nlstate);
                   2763:       free_vector(meandiff,1,nlstate);
                   2764:       return bprlim;
                   2765:     }
                   2766:   } /* age loop */
                   2767:     /* After some age loop it doesn't converge */
1.247     brouard  2768:   if(first){
                   2769:     first=1;
                   2770:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2771: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2772:   }
                   2773:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2774: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2775:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2776:   free_vector(min,1,nlstate);
                   2777:   free_vector(max,1,nlstate);
                   2778:   free_vector(meandiff,1,nlstate);
                   2779:   
                   2780:   return bprlim; /* should not reach here */
                   2781: }
                   2782: 
1.126     brouard  2783: /*************** transition probabilities ***************/ 
                   2784: 
                   2785: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2786: {
1.138     brouard  2787:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2788:      computes the probability to be observed in state j being in state i by appying the
                   2789:      model to the ncovmodel covariates (including constant and age).
                   2790:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2791:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2792:      ncth covariate in the global vector x is given by the formula:
                   2793:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2794:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2795:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2796:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2797:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2798:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2799:   */
                   2800:   double s1, lnpijopii;
1.126     brouard  2801:   /*double t34;*/
1.164     brouard  2802:   int i,j, nc, ii, jj;
1.126     brouard  2803: 
1.223     brouard  2804:   for(i=1; i<= nlstate; i++){
                   2805:     for(j=1; j<i;j++){
                   2806:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2807:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2808:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2809:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2810:       }
                   2811:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2812:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2813:     }
                   2814:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2815:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2816:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2817:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2818:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2819:       }
                   2820:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2821:     }
                   2822:   }
1.218     brouard  2823:   
1.223     brouard  2824:   for(i=1; i<= nlstate; i++){
                   2825:     s1=0;
                   2826:     for(j=1; j<i; j++){
                   2827:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2828:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2829:     }
                   2830:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2831:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2832:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2833:     }
                   2834:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2835:     ps[i][i]=1./(s1+1.);
                   2836:     /* Computing other pijs */
                   2837:     for(j=1; j<i; j++)
                   2838:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2839:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2840:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2841:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2842:   } /* end i */
1.218     brouard  2843:   
1.223     brouard  2844:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2845:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2846:       ps[ii][jj]=0;
                   2847:       ps[ii][ii]=1;
                   2848:     }
                   2849:   }
1.218     brouard  2850:   
                   2851:   
1.223     brouard  2852:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2853:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2854:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2855:   /*   } */
                   2856:   /*   printf("\n "); */
                   2857:   /* } */
                   2858:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2859:   /*
                   2860:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2861:                goto end;*/
1.223     brouard  2862:   return ps;
1.126     brouard  2863: }
                   2864: 
1.218     brouard  2865: /*************** backward transition probabilities ***************/ 
                   2866: 
                   2867:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2868: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2869:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2870: {
1.222     brouard  2871:   /* Computes the backward probability at age agefin and covariate ij
                   2872:    * and returns in **ps as well as **bmij.
                   2873:    */
1.218     brouard  2874:   int i, ii, j,k;
1.222     brouard  2875:   
                   2876:   double **out, **pmij();
                   2877:   double sumnew=0.;
1.218     brouard  2878:   double agefin;
1.222     brouard  2879:   
                   2880:   double **dnewm, **dsavm, **doldm;
                   2881:   double **bbmij;
                   2882:   
1.218     brouard  2883:   doldm=ddoldms; /* global pointers */
1.222     brouard  2884:   dnewm=ddnewms;
                   2885:   dsavm=ddsavms;
                   2886:   
                   2887:   agefin=cov[2];
                   2888:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2889:      the observed prevalence (with this covariate ij) */
                   2890:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2891:   /* We do have the matrix Px in savm  and we need pij */
                   2892:   for (j=1;j<=nlstate+ndeath;j++){
                   2893:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2894:     for (ii=1;ii<=nlstate;ii++){
                   2895:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2896:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2897:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2898:       if(sumnew >= 1.e-10){
                   2899:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2900:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2901:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2902:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2903:        /* }else */
                   2904:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2905:       }else{
1.242     brouard  2906:        ;
                   2907:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2908:       }
                   2909:     } /*End ii */
                   2910:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2911:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2912:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2913:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2914:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2915:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2916:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2917:   for (j=1;j<=nlstate+ndeath;j++){
                   2918:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2919:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2920:     }
                   2921:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2922:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2923:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2924:   /* end bmij */
                   2925:   return ps; 
1.218     brouard  2926: }
1.217     brouard  2927: /*************** transition probabilities ***************/ 
                   2928: 
1.218     brouard  2929: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2930: {
                   2931:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2932:      computes the probability to be observed in state j being in state i by appying the
                   2933:      model to the ncovmodel covariates (including constant and age).
                   2934:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2935:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2936:      ncth covariate in the global vector x is given by the formula:
                   2937:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2938:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2939:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2940:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2941:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2942:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2943:   */
                   2944:   double s1, lnpijopii;
                   2945:   /*double t34;*/
                   2946:   int i,j, nc, ii, jj;
                   2947: 
1.234     brouard  2948:   for(i=1; i<= nlstate; i++){
                   2949:     for(j=1; j<i;j++){
                   2950:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2951:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2952:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2953:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2954:       }
                   2955:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2956:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2957:     }
                   2958:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2959:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2960:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2961:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2962:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2963:       }
                   2964:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2965:     }
                   2966:   }
                   2967:   
                   2968:   for(i=1; i<= nlstate; i++){
                   2969:     s1=0;
                   2970:     for(j=1; j<i; j++){
                   2971:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2972:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2973:     }
                   2974:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2975:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2976:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2977:     }
                   2978:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2979:     ps[i][i]=1./(s1+1.);
                   2980:     /* Computing other pijs */
                   2981:     for(j=1; j<i; j++)
                   2982:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2983:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2984:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2985:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2986:   } /* end i */
                   2987:   
                   2988:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2989:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2990:       ps[ii][jj]=0;
                   2991:       ps[ii][ii]=1;
                   2992:     }
                   2993:   }
                   2994:   /* Added for backcast */ /* Transposed matrix too */
                   2995:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2996:     s1=0.;
                   2997:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2998:       s1+=ps[ii][jj];
                   2999:     }
                   3000:     for(ii=1; ii<= nlstate; ii++){
                   3001:       ps[ii][jj]=ps[ii][jj]/s1;
                   3002:     }
                   3003:   }
                   3004:   /* Transposition */
                   3005:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3006:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3007:       s1=ps[ii][jj];
                   3008:       ps[ii][jj]=ps[jj][ii];
                   3009:       ps[jj][ii]=s1;
                   3010:     }
                   3011:   }
                   3012:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3013:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3014:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3015:   /*   } */
                   3016:   /*   printf("\n "); */
                   3017:   /* } */
                   3018:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3019:   /*
                   3020:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3021:     goto end;*/
                   3022:   return ps;
1.217     brouard  3023: }
                   3024: 
                   3025: 
1.126     brouard  3026: /**************** Product of 2 matrices ******************/
                   3027: 
1.145     brouard  3028: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3029: {
                   3030:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3031:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3032:   /* in, b, out are matrice of pointers which should have been initialized 
                   3033:      before: only the contents of out is modified. The function returns
                   3034:      a pointer to pointers identical to out */
1.145     brouard  3035:   int i, j, k;
1.126     brouard  3036:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3037:     for(k=ncolol; k<=ncoloh; k++){
                   3038:       out[i][k]=0.;
                   3039:       for(j=ncl; j<=nch; j++)
                   3040:        out[i][k] +=in[i][j]*b[j][k];
                   3041:     }
1.126     brouard  3042:   return out;
                   3043: }
                   3044: 
                   3045: 
                   3046: /************* Higher Matrix Product ***************/
                   3047: 
1.235     brouard  3048: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3049: {
1.218     brouard  3050:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3051:      'nhstepm*hstepm*stepm' months (i.e. until
                   3052:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3053:      nhstepm*hstepm matrices. 
                   3054:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3055:      (typically every 2 years instead of every month which is too big 
                   3056:      for the memory).
                   3057:      Model is determined by parameters x and covariates have to be 
                   3058:      included manually here. 
                   3059: 
                   3060:      */
                   3061: 
                   3062:   int i, j, d, h, k;
1.131     brouard  3063:   double **out, cov[NCOVMAX+1];
1.126     brouard  3064:   double **newm;
1.187     brouard  3065:   double agexact;
1.214     brouard  3066:   double agebegin, ageend;
1.126     brouard  3067: 
                   3068:   /* Hstepm could be zero and should return the unit matrix */
                   3069:   for (i=1;i<=nlstate+ndeath;i++)
                   3070:     for (j=1;j<=nlstate+ndeath;j++){
                   3071:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3072:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3073:     }
                   3074:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3075:   for(h=1; h <=nhstepm; h++){
                   3076:     for(d=1; d <=hstepm; d++){
                   3077:       newm=savm;
                   3078:       /* Covariates have to be included here again */
                   3079:       cov[1]=1.;
1.214     brouard  3080:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3081:       cov[2]=agexact;
                   3082:       if(nagesqr==1)
1.227     brouard  3083:        cov[3]= agexact*agexact;
1.235     brouard  3084:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3085:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3086:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3087:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3088:       }
                   3089:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3090:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3091:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3092:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3093:       }
                   3094:       for (k=1; k<=cptcovage;k++){
                   3095:        if(Dummy[Tvar[Tage[k]]]){
                   3096:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3097:        } else{
                   3098:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3099:        }
                   3100:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3101:       }
                   3102:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3103:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3104:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3105:       }
                   3106:       /* for (k=1; k<=cptcovn;k++)  */
                   3107:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3108:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3109:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3110:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3111:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3112:       
                   3113:       
1.126     brouard  3114:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3115:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3116:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3117:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3118:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3119:       /* if((int)age == 70){ */
                   3120:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3121:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3122:       /*         printf("%d pmmij ",i); */
                   3123:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3124:       /*           printf("%f ",pmmij[i][j]); */
                   3125:       /*         } */
                   3126:       /*         printf(" oldm "); */
                   3127:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3128:       /*           printf("%f ",oldm[i][j]); */
                   3129:       /*         } */
                   3130:       /*         printf("\n"); */
                   3131:       /*       } */
                   3132:       /* } */
1.126     brouard  3133:       savm=oldm;
                   3134:       oldm=newm;
                   3135:     }
                   3136:     for(i=1; i<=nlstate+ndeath; i++)
                   3137:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3138:                                po[i][j][h]=newm[i][j];
                   3139:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3140:       }
1.128     brouard  3141:     /*printf("h=%d ",h);*/
1.126     brouard  3142:   } /* end h */
1.218     brouard  3143:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3144:   return po;
                   3145: }
                   3146: 
1.217     brouard  3147: /************* Higher Back Matrix Product ***************/
1.218     brouard  3148: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3149: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3150: {
1.218     brouard  3151:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3152:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3153:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3154:      nhstepm*hstepm matrices.
                   3155:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3156:      (typically every 2 years instead of every month which is too big
1.217     brouard  3157:      for the memory).
1.218     brouard  3158:      Model is determined by parameters x and covariates have to be
                   3159:      included manually here.
1.217     brouard  3160: 
1.222     brouard  3161:   */
1.217     brouard  3162: 
                   3163:   int i, j, d, h, k;
                   3164:   double **out, cov[NCOVMAX+1];
                   3165:   double **newm;
                   3166:   double agexact;
                   3167:   double agebegin, ageend;
1.222     brouard  3168:   double **oldm, **savm;
1.217     brouard  3169: 
1.222     brouard  3170:   oldm=oldms;savm=savms;
1.217     brouard  3171:   /* Hstepm could be zero and should return the unit matrix */
                   3172:   for (i=1;i<=nlstate+ndeath;i++)
                   3173:     for (j=1;j<=nlstate+ndeath;j++){
                   3174:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3175:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3176:     }
                   3177:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3178:   for(h=1; h <=nhstepm; h++){
                   3179:     for(d=1; d <=hstepm; d++){
                   3180:       newm=savm;
                   3181:       /* Covariates have to be included here again */
                   3182:       cov[1]=1.;
                   3183:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3184:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3185:       cov[2]=agexact;
                   3186:       if(nagesqr==1)
1.222     brouard  3187:        cov[3]= agexact*agexact;
1.218     brouard  3188:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3189:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3190:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3191:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3192:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3193:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3194:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3195:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3196:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3197:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3198:                        
                   3199:                        
1.217     brouard  3200:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3201:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3202:       /* Careful transposed matrix */
1.222     brouard  3203:       /* age is in cov[2] */
1.218     brouard  3204:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3205:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3206:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3207:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3208:       /* if((int)age == 70){ */
                   3209:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3210:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3211:       /*         printf("%d pmmij ",i); */
                   3212:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3213:       /*           printf("%f ",pmmij[i][j]); */
                   3214:       /*         } */
                   3215:       /*         printf(" oldm "); */
                   3216:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3217:       /*           printf("%f ",oldm[i][j]); */
                   3218:       /*         } */
                   3219:       /*         printf("\n"); */
                   3220:       /*       } */
                   3221:       /* } */
                   3222:       savm=oldm;
                   3223:       oldm=newm;
                   3224:     }
                   3225:     for(i=1; i<=nlstate+ndeath; i++)
                   3226:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3227:        po[i][j][h]=newm[i][j];
                   3228:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3229:       }
                   3230:     /*printf("h=%d ",h);*/
                   3231:   } /* end h */
1.222     brouard  3232:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3233:   return po;
                   3234: }
                   3235: 
                   3236: 
1.162     brouard  3237: #ifdef NLOPT
                   3238:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3239:   double fret;
                   3240:   double *xt;
                   3241:   int j;
                   3242:   myfunc_data *d2 = (myfunc_data *) pd;
                   3243: /* xt = (p1-1); */
                   3244:   xt=vector(1,n); 
                   3245:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3246: 
                   3247:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3248:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3249:   printf("Function = %.12lf ",fret);
                   3250:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3251:   printf("\n");
                   3252:  free_vector(xt,1,n);
                   3253:   return fret;
                   3254: }
                   3255: #endif
1.126     brouard  3256: 
                   3257: /*************** log-likelihood *************/
                   3258: double func( double *x)
                   3259: {
1.226     brouard  3260:   int i, ii, j, k, mi, d, kk;
                   3261:   int ioffset=0;
                   3262:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3263:   double **out;
                   3264:   double lli; /* Individual log likelihood */
                   3265:   int s1, s2;
1.228     brouard  3266:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3267:   double bbh, survp;
                   3268:   long ipmx;
                   3269:   double agexact;
                   3270:   /*extern weight */
                   3271:   /* We are differentiating ll according to initial status */
                   3272:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3273:   /*for(i=1;i<imx;i++) 
                   3274:     printf(" %d\n",s[4][i]);
                   3275:   */
1.162     brouard  3276: 
1.226     brouard  3277:   ++countcallfunc;
1.162     brouard  3278: 
1.226     brouard  3279:   cov[1]=1.;
1.126     brouard  3280: 
1.226     brouard  3281:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3282:   ioffset=0;
1.226     brouard  3283:   if(mle==1){
                   3284:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3285:       /* Computes the values of the ncovmodel covariates of the model
                   3286:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3287:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3288:         to be observed in j being in i according to the model.
                   3289:       */
1.243     brouard  3290:       ioffset=2+nagesqr ;
1.233     brouard  3291:    /* Fixed */
1.234     brouard  3292:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3293:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3294:       }
1.226     brouard  3295:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3296:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3297:         has been calculated etc */
                   3298:       /* For an individual i, wav[i] gives the number of effective waves */
                   3299:       /* We compute the contribution to Likelihood of each effective transition
                   3300:         mw[mi][i] is real wave of the mi th effectve wave */
                   3301:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3302:         s2=s[mw[mi+1][i]][i];
                   3303:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3304:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3305:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3306:       */
                   3307:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3308:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3309:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3310:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3311:        }
                   3312:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3313:          for (j=1;j<=nlstate+ndeath;j++){
                   3314:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3315:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3316:          }
                   3317:        for(d=0; d<dh[mi][i]; d++){
                   3318:          newm=savm;
                   3319:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3320:          cov[2]=agexact;
                   3321:          if(nagesqr==1)
                   3322:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3323:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3324:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3325:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3326:          else
                   3327:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3328:          }
                   3329:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3330:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3331:          savm=oldm;
                   3332:          oldm=newm;
                   3333:        } /* end mult */
                   3334:        
                   3335:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3336:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3337:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3338:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3339:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3340:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3341:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3342:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3343:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3344:                                 * -stepm/2 to stepm/2 .
                   3345:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3346:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3347:                                 */
1.234     brouard  3348:        s1=s[mw[mi][i]][i];
                   3349:        s2=s[mw[mi+1][i]][i];
                   3350:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3351:        /* bias bh is positive if real duration
                   3352:         * is higher than the multiple of stepm and negative otherwise.
                   3353:         */
                   3354:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3355:        if( s2 > nlstate){ 
                   3356:          /* i.e. if s2 is a death state and if the date of death is known 
                   3357:             then the contribution to the likelihood is the probability to 
                   3358:             die between last step unit time and current  step unit time, 
                   3359:             which is also equal to probability to die before dh 
                   3360:             minus probability to die before dh-stepm . 
                   3361:             In version up to 0.92 likelihood was computed
                   3362:             as if date of death was unknown. Death was treated as any other
                   3363:             health state: the date of the interview describes the actual state
                   3364:             and not the date of a change in health state. The former idea was
                   3365:             to consider that at each interview the state was recorded
                   3366:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3367:             introduced the exact date of death then we should have modified
                   3368:             the contribution of an exact death to the likelihood. This new
                   3369:             contribution is smaller and very dependent of the step unit
                   3370:             stepm. It is no more the probability to die between last interview
                   3371:             and month of death but the probability to survive from last
                   3372:             interview up to one month before death multiplied by the
                   3373:             probability to die within a month. Thanks to Chris
                   3374:             Jackson for correcting this bug.  Former versions increased
                   3375:             mortality artificially. The bad side is that we add another loop
                   3376:             which slows down the processing. The difference can be up to 10%
                   3377:             lower mortality.
                   3378:          */
                   3379:          /* If, at the beginning of the maximization mostly, the
                   3380:             cumulative probability or probability to be dead is
                   3381:             constant (ie = 1) over time d, the difference is equal to
                   3382:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3383:             s1 at precedent wave, to be dead a month before current
                   3384:             wave is equal to probability, being at state s1 at
                   3385:             precedent wave, to be dead at mont of the current
                   3386:             wave. Then the observed probability (that this person died)
                   3387:             is null according to current estimated parameter. In fact,
                   3388:             it should be very low but not zero otherwise the log go to
                   3389:             infinity.
                   3390:          */
1.183     brouard  3391: /* #ifdef INFINITYORIGINAL */
                   3392: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3393: /* #else */
                   3394: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3395: /*         lli=log(mytinydouble); */
                   3396: /*       else */
                   3397: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3398: /* #endif */
1.226     brouard  3399:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3400:          
1.226     brouard  3401:        } else if  ( s2==-1 ) { /* alive */
                   3402:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3403:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3404:          /*survp += out[s1][j]; */
                   3405:          lli= log(survp);
                   3406:        }
                   3407:        else if  (s2==-4) { 
                   3408:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3409:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3410:          lli= log(survp); 
                   3411:        } 
                   3412:        else if  (s2==-5) { 
                   3413:          for (j=1,survp=0. ; j<=2; j++)  
                   3414:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3415:          lli= log(survp); 
                   3416:        } 
                   3417:        else{
                   3418:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3419:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3420:        } 
                   3421:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3422:        /*if(lli ==000.0)*/
                   3423:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3424:        ipmx +=1;
                   3425:        sw += weight[i];
                   3426:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3427:        /* if (lli < log(mytinydouble)){ */
                   3428:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3429:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3430:        /* } */
                   3431:       } /* end of wave */
                   3432:     } /* end of individual */
                   3433:   }  else if(mle==2){
                   3434:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3435:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3436:       for(mi=1; mi<= wav[i]-1; mi++){
                   3437:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3438:          for (j=1;j<=nlstate+ndeath;j++){
                   3439:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3440:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3441:          }
                   3442:        for(d=0; d<=dh[mi][i]; d++){
                   3443:          newm=savm;
                   3444:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3445:          cov[2]=agexact;
                   3446:          if(nagesqr==1)
                   3447:            cov[3]= agexact*agexact;
                   3448:          for (kk=1; kk<=cptcovage;kk++) {
                   3449:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3450:          }
                   3451:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3452:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3453:          savm=oldm;
                   3454:          oldm=newm;
                   3455:        } /* end mult */
                   3456:       
                   3457:        s1=s[mw[mi][i]][i];
                   3458:        s2=s[mw[mi+1][i]][i];
                   3459:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3460:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3461:        ipmx +=1;
                   3462:        sw += weight[i];
                   3463:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3464:       } /* end of wave */
                   3465:     } /* end of individual */
                   3466:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3467:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3468:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3469:       for(mi=1; mi<= wav[i]-1; mi++){
                   3470:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3471:          for (j=1;j<=nlstate+ndeath;j++){
                   3472:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3473:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3474:          }
                   3475:        for(d=0; d<dh[mi][i]; d++){
                   3476:          newm=savm;
                   3477:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3478:          cov[2]=agexact;
                   3479:          if(nagesqr==1)
                   3480:            cov[3]= agexact*agexact;
                   3481:          for (kk=1; kk<=cptcovage;kk++) {
                   3482:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3483:          }
                   3484:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3485:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3486:          savm=oldm;
                   3487:          oldm=newm;
                   3488:        } /* end mult */
                   3489:       
                   3490:        s1=s[mw[mi][i]][i];
                   3491:        s2=s[mw[mi+1][i]][i];
                   3492:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3493:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3494:        ipmx +=1;
                   3495:        sw += weight[i];
                   3496:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3497:       } /* end of wave */
                   3498:     } /* end of individual */
                   3499:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3500:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3501:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3502:       for(mi=1; mi<= wav[i]-1; mi++){
                   3503:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3504:          for (j=1;j<=nlstate+ndeath;j++){
                   3505:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3506:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3507:          }
                   3508:        for(d=0; d<dh[mi][i]; d++){
                   3509:          newm=savm;
                   3510:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3511:          cov[2]=agexact;
                   3512:          if(nagesqr==1)
                   3513:            cov[3]= agexact*agexact;
                   3514:          for (kk=1; kk<=cptcovage;kk++) {
                   3515:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3516:          }
1.126     brouard  3517:        
1.226     brouard  3518:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3519:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3520:          savm=oldm;
                   3521:          oldm=newm;
                   3522:        } /* end mult */
                   3523:       
                   3524:        s1=s[mw[mi][i]][i];
                   3525:        s2=s[mw[mi+1][i]][i];
                   3526:        if( s2 > nlstate){ 
                   3527:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3528:        } else if  ( s2==-1 ) { /* alive */
                   3529:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3530:            survp += out[s1][j];
                   3531:          lli= log(survp);
                   3532:        }else{
                   3533:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3534:        }
                   3535:        ipmx +=1;
                   3536:        sw += weight[i];
                   3537:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3538: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3539:       } /* end of wave */
                   3540:     } /* end of individual */
                   3541:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3542:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3543:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3544:       for(mi=1; mi<= wav[i]-1; mi++){
                   3545:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3546:          for (j=1;j<=nlstate+ndeath;j++){
                   3547:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3548:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3549:          }
                   3550:        for(d=0; d<dh[mi][i]; d++){
                   3551:          newm=savm;
                   3552:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3553:          cov[2]=agexact;
                   3554:          if(nagesqr==1)
                   3555:            cov[3]= agexact*agexact;
                   3556:          for (kk=1; kk<=cptcovage;kk++) {
                   3557:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3558:          }
1.126     brouard  3559:        
1.226     brouard  3560:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3561:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3562:          savm=oldm;
                   3563:          oldm=newm;
                   3564:        } /* end mult */
                   3565:       
                   3566:        s1=s[mw[mi][i]][i];
                   3567:        s2=s[mw[mi+1][i]][i];
                   3568:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3569:        ipmx +=1;
                   3570:        sw += weight[i];
                   3571:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3572:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3573:       } /* end of wave */
                   3574:     } /* end of individual */
                   3575:   } /* End of if */
                   3576:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3577:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3578:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3579:   return -l;
1.126     brouard  3580: }
                   3581: 
                   3582: /*************** log-likelihood *************/
                   3583: double funcone( double *x)
                   3584: {
1.228     brouard  3585:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3586:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3587:   int ioffset=0;
1.131     brouard  3588:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3589:   double **out;
                   3590:   double lli; /* Individual log likelihood */
                   3591:   double llt;
                   3592:   int s1, s2;
1.228     brouard  3593:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3594: 
1.126     brouard  3595:   double bbh, survp;
1.187     brouard  3596:   double agexact;
1.214     brouard  3597:   double agebegin, ageend;
1.126     brouard  3598:   /*extern weight */
                   3599:   /* We are differentiating ll according to initial status */
                   3600:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3601:   /*for(i=1;i<imx;i++) 
                   3602:     printf(" %d\n",s[4][i]);
                   3603:   */
                   3604:   cov[1]=1.;
                   3605: 
                   3606:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3607:   ioffset=0;
                   3608:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3609:     /* ioffset=2+nagesqr+cptcovage; */
                   3610:     ioffset=2+nagesqr;
1.232     brouard  3611:     /* Fixed */
1.224     brouard  3612:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3613:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3614:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3615:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3616: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3617: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3618: /*    cov[2+6]=covar[2][i]; V2  */
                   3619: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3620: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3621: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3622: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3623: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3624: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3625:     }
1.232     brouard  3626:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3627:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3628:     /* } */
1.231     brouard  3629:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3630:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3631:     /* } */
1.225     brouard  3632:     
1.233     brouard  3633: 
                   3634:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3635:     /* Wave varying (but not age varying) */
                   3636:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3637:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3638:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3639:       }
1.232     brouard  3640:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3641:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3642:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3643:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3644:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3645:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3646:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3647:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3648:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3649:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3650:       /* } */
1.126     brouard  3651:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3652:        for (j=1;j<=nlstate+ndeath;j++){
                   3653:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3654:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3655:        }
1.214     brouard  3656:       
                   3657:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3658:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3659:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3660:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3661:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3662:          and mw[mi+1][i]. dh depends on stepm.*/
                   3663:        newm=savm;
1.247     brouard  3664:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3665:        cov[2]=agexact;
                   3666:        if(nagesqr==1)
                   3667:          cov[3]= agexact*agexact;
                   3668:        for (kk=1; kk<=cptcovage;kk++) {
                   3669:          if(!FixedV[Tvar[Tage[kk]]])
                   3670:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3671:          else
                   3672:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3673:        }
                   3674:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3675:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3676:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3677:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3678:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3679:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3680:        savm=oldm;
                   3681:        oldm=newm;
1.126     brouard  3682:       } /* end mult */
                   3683:       
                   3684:       s1=s[mw[mi][i]][i];
                   3685:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3686:       /* if(s2==-1){ */
                   3687:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3688:       /*       /\* exit(1); *\/ */
                   3689:       /* } */
1.126     brouard  3690:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3691:       /* bias is positive if real duration
                   3692:        * is higher than the multiple of stepm and negative otherwise.
                   3693:        */
                   3694:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3695:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3696:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3697:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3698:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3699:        lli= log(survp);
1.126     brouard  3700:       }else if (mle==1){
1.242     brouard  3701:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3702:       } else if(mle==2){
1.242     brouard  3703:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3704:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3705:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3706:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3707:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3708:       } else{  /* mle=0 back to 1 */
1.242     brouard  3709:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3710:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3711:       } /* End of if */
                   3712:       ipmx +=1;
                   3713:       sw += weight[i];
                   3714:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3715:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3716:       if(globpr){
1.246     brouard  3717:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3718:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3719:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3720:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3721:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3722:          llt +=ll[k]*gipmx/gsw;
                   3723:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3724:        }
                   3725:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3726:       }
1.232     brouard  3727:        } /* end of wave */
                   3728: } /* end of individual */
                   3729: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3730: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3731: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3732: if(globpr==0){ /* First time we count the contributions and weights */
                   3733:        gipmx=ipmx;
                   3734:        gsw=sw;
                   3735: }
                   3736: return -l;
1.126     brouard  3737: }
                   3738: 
                   3739: 
                   3740: /*************** function likelione ***********/
                   3741: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3742: {
                   3743:   /* This routine should help understanding what is done with 
                   3744:      the selection of individuals/waves and
                   3745:      to check the exact contribution to the likelihood.
                   3746:      Plotting could be done.
                   3747:    */
                   3748:   int k;
                   3749: 
                   3750:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3751:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3752:     strcat(fileresilk,fileresu);
1.126     brouard  3753:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3754:       printf("Problem with resultfile: %s\n", fileresilk);
                   3755:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3756:     }
1.214     brouard  3757:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3758:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3759:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3760:     for(k=1; k<=nlstate; k++) 
                   3761:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3762:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3763:   }
                   3764: 
                   3765:   *fretone=(*funcone)(p);
                   3766:   if(*globpri !=0){
                   3767:     fclose(ficresilk);
1.205     brouard  3768:     if (mle ==0)
                   3769:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3770:     else if(mle >=1)
                   3771:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3772:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3773:     
1.208     brouard  3774:       
                   3775:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3776:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3777: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3778:     }
1.207     brouard  3779:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3780: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3781:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3782: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3783:     fflush(fichtm);
1.205     brouard  3784:   }
1.126     brouard  3785:   return;
                   3786: }
                   3787: 
                   3788: 
                   3789: /*********** Maximum Likelihood Estimation ***************/
                   3790: 
                   3791: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3792: {
1.165     brouard  3793:   int i,j, iter=0;
1.126     brouard  3794:   double **xi;
                   3795:   double fret;
                   3796:   double fretone; /* Only one call to likelihood */
                   3797:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3798: 
                   3799: #ifdef NLOPT
                   3800:   int creturn;
                   3801:   nlopt_opt opt;
                   3802:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3803:   double *lb;
                   3804:   double minf; /* the minimum objective value, upon return */
                   3805:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3806:   myfunc_data dinst, *d = &dinst;
                   3807: #endif
                   3808: 
                   3809: 
1.126     brouard  3810:   xi=matrix(1,npar,1,npar);
                   3811:   for (i=1;i<=npar;i++)
                   3812:     for (j=1;j<=npar;j++)
                   3813:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3814:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3815:   strcpy(filerespow,"POW_"); 
1.126     brouard  3816:   strcat(filerespow,fileres);
                   3817:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3818:     printf("Problem with resultfile: %s\n", filerespow);
                   3819:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3820:   }
                   3821:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3822:   for (i=1;i<=nlstate;i++)
                   3823:     for(j=1;j<=nlstate+ndeath;j++)
                   3824:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3825:   fprintf(ficrespow,"\n");
1.162     brouard  3826: #ifdef POWELL
1.126     brouard  3827:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3828: #endif
1.126     brouard  3829: 
1.162     brouard  3830: #ifdef NLOPT
                   3831: #ifdef NEWUOA
                   3832:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3833: #else
                   3834:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3835: #endif
                   3836:   lb=vector(0,npar-1);
                   3837:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3838:   nlopt_set_lower_bounds(opt, lb);
                   3839:   nlopt_set_initial_step1(opt, 0.1);
                   3840:   
                   3841:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3842:   d->function = func;
                   3843:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3844:   nlopt_set_min_objective(opt, myfunc, d);
                   3845:   nlopt_set_xtol_rel(opt, ftol);
                   3846:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3847:     printf("nlopt failed! %d\n",creturn); 
                   3848:   }
                   3849:   else {
                   3850:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3851:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3852:     iter=1; /* not equal */
                   3853:   }
                   3854:   nlopt_destroy(opt);
                   3855: #endif
1.126     brouard  3856:   free_matrix(xi,1,npar,1,npar);
                   3857:   fclose(ficrespow);
1.203     brouard  3858:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3859:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3860:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3861: 
                   3862: }
                   3863: 
                   3864: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3865: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3866: {
                   3867:   double  **a,**y,*x,pd;
1.203     brouard  3868:   /* double **hess; */
1.164     brouard  3869:   int i, j;
1.126     brouard  3870:   int *indx;
                   3871: 
                   3872:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3873:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3874:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3875:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3876:   double gompertz(double p[]);
1.203     brouard  3877:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3878: 
                   3879:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3880:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3881:   for (i=1;i<=npar;i++){
1.203     brouard  3882:     printf("%d-",i);fflush(stdout);
                   3883:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3884:    
                   3885:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3886:     
                   3887:     /*  printf(" %f ",p[i]);
                   3888:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3889:   }
                   3890:   
                   3891:   for (i=1;i<=npar;i++) {
                   3892:     for (j=1;j<=npar;j++)  {
                   3893:       if (j>i) { 
1.203     brouard  3894:        printf(".%d-%d",i,j);fflush(stdout);
                   3895:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3896:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3897:        
                   3898:        hess[j][i]=hess[i][j];    
                   3899:        /*printf(" %lf ",hess[i][j]);*/
                   3900:       }
                   3901:     }
                   3902:   }
                   3903:   printf("\n");
                   3904:   fprintf(ficlog,"\n");
                   3905: 
                   3906:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3907:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3908:   
                   3909:   a=matrix(1,npar,1,npar);
                   3910:   y=matrix(1,npar,1,npar);
                   3911:   x=vector(1,npar);
                   3912:   indx=ivector(1,npar);
                   3913:   for (i=1;i<=npar;i++)
                   3914:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3915:   ludcmp(a,npar,indx,&pd);
                   3916: 
                   3917:   for (j=1;j<=npar;j++) {
                   3918:     for (i=1;i<=npar;i++) x[i]=0;
                   3919:     x[j]=1;
                   3920:     lubksb(a,npar,indx,x);
                   3921:     for (i=1;i<=npar;i++){ 
                   3922:       matcov[i][j]=x[i];
                   3923:     }
                   3924:   }
                   3925: 
                   3926:   printf("\n#Hessian matrix#\n");
                   3927:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3928:   for (i=1;i<=npar;i++) { 
                   3929:     for (j=1;j<=npar;j++) { 
1.203     brouard  3930:       printf("%.6e ",hess[i][j]);
                   3931:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3932:     }
                   3933:     printf("\n");
                   3934:     fprintf(ficlog,"\n");
                   3935:   }
                   3936: 
1.203     brouard  3937:   /* printf("\n#Covariance matrix#\n"); */
                   3938:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3939:   /* for (i=1;i<=npar;i++) {  */
                   3940:   /*   for (j=1;j<=npar;j++) {  */
                   3941:   /*     printf("%.6e ",matcov[i][j]); */
                   3942:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3943:   /*   } */
                   3944:   /*   printf("\n"); */
                   3945:   /*   fprintf(ficlog,"\n"); */
                   3946:   /* } */
                   3947: 
1.126     brouard  3948:   /* Recompute Inverse */
1.203     brouard  3949:   /* for (i=1;i<=npar;i++) */
                   3950:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3951:   /* ludcmp(a,npar,indx,&pd); */
                   3952: 
                   3953:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3954: 
                   3955:   /* for (j=1;j<=npar;j++) { */
                   3956:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3957:   /*   x[j]=1; */
                   3958:   /*   lubksb(a,npar,indx,x); */
                   3959:   /*   for (i=1;i<=npar;i++){  */
                   3960:   /*     y[i][j]=x[i]; */
                   3961:   /*     printf("%.3e ",y[i][j]); */
                   3962:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3963:   /*   } */
                   3964:   /*   printf("\n"); */
                   3965:   /*   fprintf(ficlog,"\n"); */
                   3966:   /* } */
                   3967: 
                   3968:   /* Verifying the inverse matrix */
                   3969: #ifdef DEBUGHESS
                   3970:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3971: 
1.203     brouard  3972:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3973:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3974: 
                   3975:   for (j=1;j<=npar;j++) {
                   3976:     for (i=1;i<=npar;i++){ 
1.203     brouard  3977:       printf("%.2f ",y[i][j]);
                   3978:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3979:     }
                   3980:     printf("\n");
                   3981:     fprintf(ficlog,"\n");
                   3982:   }
1.203     brouard  3983: #endif
1.126     brouard  3984: 
                   3985:   free_matrix(a,1,npar,1,npar);
                   3986:   free_matrix(y,1,npar,1,npar);
                   3987:   free_vector(x,1,npar);
                   3988:   free_ivector(indx,1,npar);
1.203     brouard  3989:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3990: 
                   3991: 
                   3992: }
                   3993: 
                   3994: /*************** hessian matrix ****************/
                   3995: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3996: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3997:   int i;
                   3998:   int l=1, lmax=20;
1.203     brouard  3999:   double k1,k2, res, fx;
1.132     brouard  4000:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4001:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4002:   int k=0,kmax=10;
                   4003:   double l1;
                   4004: 
                   4005:   fx=func(x);
                   4006:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4007:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4008:     l1=pow(10,l);
                   4009:     delts=delt;
                   4010:     for(k=1 ; k <kmax; k=k+1){
                   4011:       delt = delta*(l1*k);
                   4012:       p2[theta]=x[theta] +delt;
1.145     brouard  4013:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4014:       p2[theta]=x[theta]-delt;
                   4015:       k2=func(p2)-fx;
                   4016:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4017:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4018:       
1.203     brouard  4019: #ifdef DEBUGHESSII
1.126     brouard  4020:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4021:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4022: #endif
                   4023:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4024:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4025:        k=kmax;
                   4026:       }
                   4027:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4028:        k=kmax; l=lmax*10;
1.126     brouard  4029:       }
                   4030:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4031:        delts=delt;
                   4032:       }
1.203     brouard  4033:     } /* End loop k */
1.126     brouard  4034:   }
                   4035:   delti[theta]=delts;
                   4036:   return res; 
                   4037:   
                   4038: }
                   4039: 
1.203     brouard  4040: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4041: {
                   4042:   int i;
1.164     brouard  4043:   int l=1, lmax=20;
1.126     brouard  4044:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4045:   double p2[MAXPARM+1];
1.203     brouard  4046:   int k, kmax=1;
                   4047:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4048: 
                   4049:   int firstime=0;
1.203     brouard  4050:   
1.126     brouard  4051:   fx=func(x);
1.203     brouard  4052:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4053:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4054:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4055:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4056:     k1=func(p2)-fx;
                   4057:   
1.203     brouard  4058:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4059:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4060:     k2=func(p2)-fx;
                   4061:   
1.203     brouard  4062:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4063:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4064:     k3=func(p2)-fx;
                   4065:   
1.203     brouard  4066:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4067:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4068:     k4=func(p2)-fx;
1.203     brouard  4069:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4070:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4071:       firstime=1;
1.203     brouard  4072:       kmax=kmax+10;
1.208     brouard  4073:     }
                   4074:     if(kmax >=10 || firstime ==1){
1.246     brouard  4075:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4076:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4077:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4078:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4079:     }
                   4080: #ifdef DEBUGHESSIJ
                   4081:     v1=hess[thetai][thetai];
                   4082:     v2=hess[thetaj][thetaj];
                   4083:     cv12=res;
                   4084:     /* Computing eigen value of Hessian matrix */
                   4085:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4086:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4087:     if ((lc2 <0) || (lc1 <0) ){
                   4088:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4089:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4090:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4091:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4092:     }
1.126     brouard  4093: #endif
                   4094:   }
                   4095:   return res;
                   4096: }
                   4097: 
1.203     brouard  4098:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4099: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4100: /* { */
                   4101: /*   int i; */
                   4102: /*   int l=1, lmax=20; */
                   4103: /*   double k1,k2,k3,k4,res,fx; */
                   4104: /*   double p2[MAXPARM+1]; */
                   4105: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4106: /*   int k=0,kmax=10; */
                   4107: /*   double l1; */
                   4108:   
                   4109: /*   fx=func(x); */
                   4110: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4111: /*     l1=pow(10,l); */
                   4112: /*     delts=delt; */
                   4113: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4114: /*       delt = delti*(l1*k); */
                   4115: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4116: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4117: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4118: /*       k1=func(p2)-fx; */
                   4119:       
                   4120: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4121: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4122: /*       k2=func(p2)-fx; */
                   4123:       
                   4124: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4125: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4126: /*       k3=func(p2)-fx; */
                   4127:       
                   4128: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4129: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4130: /*       k4=func(p2)-fx; */
                   4131: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4132: /* #ifdef DEBUGHESSIJ */
                   4133: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4134: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4135: /* #endif */
                   4136: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4137: /*     k=kmax; */
                   4138: /*       } */
                   4139: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4140: /*     k=kmax; l=lmax*10; */
                   4141: /*       } */
                   4142: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4143: /*     delts=delt; */
                   4144: /*       } */
                   4145: /*     } /\* End loop k *\/ */
                   4146: /*   } */
                   4147: /*   delti[theta]=delts; */
                   4148: /*   return res;  */
                   4149: /* } */
                   4150: 
                   4151: 
1.126     brouard  4152: /************** Inverse of matrix **************/
                   4153: void ludcmp(double **a, int n, int *indx, double *d) 
                   4154: { 
                   4155:   int i,imax,j,k; 
                   4156:   double big,dum,sum,temp; 
                   4157:   double *vv; 
                   4158:  
                   4159:   vv=vector(1,n); 
                   4160:   *d=1.0; 
                   4161:   for (i=1;i<=n;i++) { 
                   4162:     big=0.0; 
                   4163:     for (j=1;j<=n;j++) 
                   4164:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4165:     if (big == 0.0){
                   4166:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4167:       for (j=1;j<=n;j++) {
                   4168:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4169:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4170:       }
                   4171:       fflush(ficlog);
                   4172:       fclose(ficlog);
                   4173:       nrerror("Singular matrix in routine ludcmp"); 
                   4174:     }
1.126     brouard  4175:     vv[i]=1.0/big; 
                   4176:   } 
                   4177:   for (j=1;j<=n;j++) { 
                   4178:     for (i=1;i<j;i++) { 
                   4179:       sum=a[i][j]; 
                   4180:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4181:       a[i][j]=sum; 
                   4182:     } 
                   4183:     big=0.0; 
                   4184:     for (i=j;i<=n;i++) { 
                   4185:       sum=a[i][j]; 
                   4186:       for (k=1;k<j;k++) 
                   4187:        sum -= a[i][k]*a[k][j]; 
                   4188:       a[i][j]=sum; 
                   4189:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4190:        big=dum; 
                   4191:        imax=i; 
                   4192:       } 
                   4193:     } 
                   4194:     if (j != imax) { 
                   4195:       for (k=1;k<=n;k++) { 
                   4196:        dum=a[imax][k]; 
                   4197:        a[imax][k]=a[j][k]; 
                   4198:        a[j][k]=dum; 
                   4199:       } 
                   4200:       *d = -(*d); 
                   4201:       vv[imax]=vv[j]; 
                   4202:     } 
                   4203:     indx[j]=imax; 
                   4204:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4205:     if (j != n) { 
                   4206:       dum=1.0/(a[j][j]); 
                   4207:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4208:     } 
                   4209:   } 
                   4210:   free_vector(vv,1,n);  /* Doesn't work */
                   4211: ;
                   4212: } 
                   4213: 
                   4214: void lubksb(double **a, int n, int *indx, double b[]) 
                   4215: { 
                   4216:   int i,ii=0,ip,j; 
                   4217:   double sum; 
                   4218:  
                   4219:   for (i=1;i<=n;i++) { 
                   4220:     ip=indx[i]; 
                   4221:     sum=b[ip]; 
                   4222:     b[ip]=b[i]; 
                   4223:     if (ii) 
                   4224:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4225:     else if (sum) ii=i; 
                   4226:     b[i]=sum; 
                   4227:   } 
                   4228:   for (i=n;i>=1;i--) { 
                   4229:     sum=b[i]; 
                   4230:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4231:     b[i]=sum/a[i][i]; 
                   4232:   } 
                   4233: } 
                   4234: 
                   4235: void pstamp(FILE *fichier)
                   4236: {
1.196     brouard  4237:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4238: }
                   4239: 
1.253     brouard  4240: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4241: 
                   4242:   /* y=a+bx regression */
                   4243:   double   sumx = 0.0;                        /* sum of x                      */
                   4244:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4245:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4246:   double   sumy = 0.0;                        /* sum of y                      */
                   4247:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4248:   double   sume2; /* sum of square or residuals */
                   4249:   double yhat;
                   4250:   
                   4251:   double denom=0;
                   4252:   int i;
                   4253:   int ne=*no;
                   4254:   
                   4255:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4256:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4257:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4258:       continue;
                   4259:     }
                   4260:     ne=ne+1;
                   4261:     sumx  += x[i];       
                   4262:     sumx2 += x[i]*x[i];  
                   4263:     sumxy += x[i] * y[i];
                   4264:     sumy  += y[i];      
                   4265:     sumy2 += y[i]*y[i]; 
                   4266:     denom = (ne * sumx2 - sumx*sumx);
                   4267:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4268:   } 
                   4269:   
                   4270:   denom = (ne * sumx2 - sumx*sumx);
                   4271:   if (denom == 0) {
                   4272:     // vertical, slope m is infinity
                   4273:     *b = INFINITY;
                   4274:     *a = 0;
                   4275:     if (r) *r = 0;
                   4276:     return 1;
                   4277:   }
                   4278:   
                   4279:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4280:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4281:   if (r!=NULL) {
                   4282:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4283:       sqrt((sumx2 - sumx*sumx/ne) *
                   4284:           (sumy2 - sumy*sumy/ne));
                   4285:   }
                   4286:   *no=ne;
                   4287:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4288:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4289:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4290:       continue;
                   4291:     }
                   4292:     ne=ne+1;
                   4293:     yhat = y[i] - *a -*b* x[i];
                   4294:     sume2  += yhat * yhat ;       
                   4295:     
                   4296:     denom = (ne * sumx2 - sumx*sumx);
                   4297:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4298:   } 
                   4299:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4300:   *sa= *sb * sqrt(sumx2/ne);
                   4301:   
                   4302:   return 0; 
                   4303: }
                   4304: 
1.126     brouard  4305: /************ Frequencies ********************/
1.251     brouard  4306: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4307:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4308:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4309: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4310:   
1.265   ! brouard  4311:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4312:   int iind=0, iage=0;
                   4313:   int mi; /* Effective wave */
                   4314:   int first;
                   4315:   double ***freq; /* Frequencies */
1.253     brouard  4316:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4317:   int no;
1.226     brouard  4318:   double *meanq;
                   4319:   double **meanqt;
                   4320:   double *pp, **prop, *posprop, *pospropt;
                   4321:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4322:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4323:   double agebegin, ageend;
                   4324:     
                   4325:   pp=vector(1,nlstate);
1.251     brouard  4326:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4327:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4328:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4329:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4330:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4331:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4332:   strcpy(fileresp,"P_");
                   4333:   strcat(fileresp,fileresu);
                   4334:   /*strcat(fileresphtm,fileresu);*/
                   4335:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4336:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4337:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4338:     exit(0);
                   4339:   }
1.240     brouard  4340:   
1.226     brouard  4341:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4342:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4343:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4344:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4345:     fflush(ficlog);
                   4346:     exit(70); 
                   4347:   }
                   4348:   else{
                   4349:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4350: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4351: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4352:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4353:   }
1.237     brouard  4354:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4355:   
1.226     brouard  4356:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4357:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4358:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4359:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4360:     fflush(ficlog);
                   4361:     exit(70); 
1.240     brouard  4362:   } else{
1.226     brouard  4363:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4364: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4365: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4366:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4367:   }
1.240     brouard  4368:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4369:   
1.253     brouard  4370:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4371:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4372:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4373:   j1=0;
1.126     brouard  4374:   
1.227     brouard  4375:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4376:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4377:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4378:   
                   4379:   
1.226     brouard  4380:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4381:      reference=low_education V1=0,V2=0
                   4382:      med_educ                V1=1 V2=0, 
                   4383:      high_educ               V1=0 V2=1
                   4384:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4385:   */
1.249     brouard  4386:   dateintsum=0;
                   4387:   k2cpt=0;
                   4388: 
1.253     brouard  4389:   if(cptcoveff == 0 )
1.265   ! brouard  4390:     nl=1;  /* Constant and age model only */
1.253     brouard  4391:   else
                   4392:     nl=2;
1.265   ! brouard  4393: 
        !          4394:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
        !          4395:   /* Loop on nj=1 or 2 if dummy covariates j!=0
        !          4396:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
        !          4397:    *     freq[s1][s2][iage] =0.
        !          4398:    *     Loop on iind
        !          4399:    *       ++freq[s1][s2][iage] weighted
        !          4400:    *     end iind
        !          4401:    *     if covariate and j!0
        !          4402:    *       headers Variable on one line
        !          4403:    *     endif cov j!=0
        !          4404:    *     header of frequency table by age
        !          4405:    *     Loop on age
        !          4406:    *       pp[s1]+=freq[s1][s2][iage] weighted
        !          4407:    *       pos+=freq[s1][s2][iage] weighted
        !          4408:    *       Loop on s1 initial state
        !          4409:    *         fprintf(ficresp
        !          4410:    *       end s1
        !          4411:    *     end age
        !          4412:    *     if j!=0 computes starting values
        !          4413:    *     end compute starting values
        !          4414:    *   end j1
        !          4415:    * end nl 
        !          4416:    */
1.253     brouard  4417:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4418:     if(nj==1)
                   4419:       j=0;  /* First pass for the constant */
1.265   ! brouard  4420:     else{
1.253     brouard  4421:       j=cptcoveff; /* Other passes for the covariate values */
1.265   ! brouard  4422:     }
1.251     brouard  4423:     first=1;
1.265   ! brouard  4424:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4425:       posproptt=0.;
                   4426:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4427:        scanf("%d", i);*/
                   4428:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265   ! brouard  4429:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4430:          for(m=iagemin; m <= iagemax+3; m++)
1.265   ! brouard  4431:            freq[i][s2][m]=0;
1.251     brouard  4432:       
                   4433:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4434:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4435:          prop[i][m]=0;
                   4436:        posprop[i]=0;
                   4437:        pospropt[i]=0;
                   4438:       }
                   4439:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4440:       /*   meanq[z1]+=0.; */
                   4441:       /*   for(m=1;m<=lastpass;m++){ */
                   4442:       /*       meanqt[m][z1]=0.; */
                   4443:       /*   } */
                   4444:       /* } */
                   4445:       
                   4446:       /* dateintsum=0; */
                   4447:       /* k2cpt=0; */
                   4448:       
1.265   ! brouard  4449:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4450:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4451:        bool=1;
                   4452:        if(j !=0){
                   4453:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4454:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4455:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4456:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4457:              /* } */
                   4458:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4459:                /* if(Tvaraff[z1] ==-20){ */
                   4460:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4461:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4462:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4463:                /* }else  */
                   4464:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265   ! brouard  4465:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4466:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4467:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4468:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4469:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4470:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4471:                } /* Onlyf fixed */
                   4472:              } /* end z1 */
                   4473:            } /* cptcovn > 0 */
                   4474:          } /* end any */
                   4475:        }/* end j==0 */
1.265   ! brouard  4476:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4477:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4478:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4479:            m=mw[mi][iind];
                   4480:            if(j!=0){
                   4481:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4482:                for (z1=1; z1<=cptcoveff; z1++) {
                   4483:                  if( Fixed[Tmodelind[z1]]==1){
                   4484:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4485:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4486:                                                                                      value is -1, we don't select. It differs from the 
                   4487:                                                                                      constant and age model which counts them. */
                   4488:                      bool=0; /* not selected */
                   4489:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4490:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4491:                      bool=0;
                   4492:                    }
                   4493:                  }
                   4494:                }
                   4495:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4496:            } /* end j==0 */
                   4497:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4498:            if(bool==1){
                   4499:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4500:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4501:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4502:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4503:              if(m >=firstpass && m <=lastpass){
                   4504:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4505:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4506:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4507:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4508:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4509:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4510:                if (m<lastpass) {
                   4511:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4512:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4513:                  if(s[m][iind]==-1)
                   4514:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4515:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4516:                  /* if((int)agev[m][iind] == 55) */
                   4517:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4518:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4519:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4520:                }
1.251     brouard  4521:              } /* end if between passes */  
                   4522:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4523:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4524:                k2cpt++;
                   4525:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4526:              }
1.251     brouard  4527:            }else{
                   4528:              bool=1;
                   4529:            }/* end bool 2 */
                   4530:          } /* end m */
                   4531:        } /* end bool */
                   4532:       } /* end iind = 1 to imx */
                   4533:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4534:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4535:       
                   4536:       
                   4537:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265   ! brouard  4538:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
        !          4539:         pstamp(ficresp);
1.251     brouard  4540:       if  (cptcoveff>0 && j!=0){
1.265   ! brouard  4541:         pstamp(ficresp);
1.251     brouard  4542:        printf( "\n#********** Variable "); 
                   4543:        fprintf(ficresp, "\n#********** Variable "); 
                   4544:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4545:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4546:        fprintf(ficlog, "\n#********** Variable "); 
                   4547:        for (z1=1; z1<=cptcoveff; z1++){
                   4548:          if(!FixedV[Tvaraff[z1]]){
                   4549:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4550:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4551:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4552:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4553:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4554:          }else{
1.251     brouard  4555:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4556:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4557:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4558:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4559:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4560:          }
                   4561:        }
                   4562:        printf( "**********\n#");
                   4563:        fprintf(ficresp, "**********\n#");
                   4564:        fprintf(ficresphtm, "**********</h3>\n");
                   4565:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4566:        fprintf(ficlog, "**********\n");
                   4567:       }
                   4568:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265   ! brouard  4569:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
        !          4570:         fprintf(ficresp, " Age");
        !          4571:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4572:       for(i=1; i<=nlstate;i++) {
1.265   ! brouard  4573:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4574:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4575:       }
1.265   ! brouard  4576:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4577:       fprintf(ficresphtm, "\n");
                   4578:       
                   4579:       /* Header of frequency table by age */
                   4580:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4581:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265   ! brouard  4582:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4583:        for(m=-1; m <=nlstate+ndeath; m++){
1.265   ! brouard  4584:          if(s2!=0 && m!=0)
        !          4585:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4586:        }
1.226     brouard  4587:       }
1.251     brouard  4588:       fprintf(ficresphtmfr, "\n");
                   4589:     
                   4590:       /* For each age */
                   4591:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4592:        fprintf(ficresphtm,"<tr>");
                   4593:        if(iage==iagemax+1){
                   4594:          fprintf(ficlog,"1");
                   4595:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4596:        }else if(iage==iagemax+2){
                   4597:          fprintf(ficlog,"0");
                   4598:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4599:        }else if(iage==iagemax+3){
                   4600:          fprintf(ficlog,"Total");
                   4601:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4602:        }else{
1.240     brouard  4603:          if(first==1){
1.251     brouard  4604:            first=0;
                   4605:            printf("See log file for details...\n");
                   4606:          }
                   4607:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4608:          fprintf(ficlog,"Age %d", iage);
                   4609:        }
1.265   ! brouard  4610:        for(s1=1; s1 <=nlstate ; s1++){
        !          4611:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
        !          4612:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4613:        }
1.265   ! brouard  4614:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4615:          for(m=-1, pos=0; m <=0 ; m++)
1.265   ! brouard  4616:            pos += freq[s1][m][iage];
        !          4617:          if(pp[s1]>=1.e-10){
1.251     brouard  4618:            if(first==1){
1.265   ! brouard  4619:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4620:            }
1.265   ! brouard  4621:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4622:          }else{
                   4623:            if(first==1)
1.265   ! brouard  4624:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
        !          4625:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4626:          }
                   4627:        }
                   4628:       
1.265   ! brouard  4629:        for(s1=1; s1 <=nlstate ; s1++){ 
        !          4630:          /* posprop[s1]=0; */
        !          4631:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
        !          4632:            pp[s1] += freq[s1][m][iage];
        !          4633:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
        !          4634:       
        !          4635:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
        !          4636:          pos += pp[s1]; /* pos is the total number of transitions until this age */
        !          4637:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
        !          4638:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
        !          4639:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
        !          4640:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
        !          4641:        }
        !          4642:        
        !          4643:        /* Writing ficresp */
        !          4644:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
        !          4645:           if( iage <= iagemax){
        !          4646:            fprintf(ficresp," %d",iage);
        !          4647:           }
        !          4648:         }else if( nj==2){
        !          4649:           if( iage <= iagemax){
        !          4650:            fprintf(ficresp," %d",iage);
        !          4651:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
        !          4652:           }
1.240     brouard  4653:        }
1.265   ! brouard  4654:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4655:          if(pos>=1.e-5){
1.251     brouard  4656:            if(first==1)
1.265   ! brouard  4657:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
        !          4658:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4659:          }else{
                   4660:            if(first==1)
1.265   ! brouard  4661:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
        !          4662:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4663:          }
                   4664:          if( iage <= iagemax){
                   4665:            if(pos>=1.e-5){
1.265   ! brouard  4666:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
        !          4667:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
        !          4668:               }else if( nj==2){
        !          4669:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
        !          4670:               }
        !          4671:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
        !          4672:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
        !          4673:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
        !          4674:            } else{
        !          4675:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
        !          4676:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4677:            }
1.240     brouard  4678:          }
1.265   ! brouard  4679:          pospropt[s1] +=posprop[s1];
        !          4680:        } /* end loop s1 */
1.251     brouard  4681:        /* pospropt=0.; */
1.265   ! brouard  4682:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4683:          for(m=-1; m <=nlstate+ndeath; m++){
1.265   ! brouard  4684:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4685:              if(first==1){
1.265   ! brouard  4686:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4687:              }
1.265   ! brouard  4688:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
        !          4689:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4690:            }
1.265   ! brouard  4691:            if(s1!=0 && m!=0)
        !          4692:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4693:          }
1.265   ! brouard  4694:        } /* end loop s1 */
1.251     brouard  4695:        posproptt=0.; 
1.265   ! brouard  4696:        for(s1=1; s1 <=nlstate; s1++){
        !          4697:          posproptt += pospropt[s1];
1.251     brouard  4698:        }
                   4699:        fprintf(ficresphtmfr,"</tr>\n ");
1.265   ! brouard  4700:        fprintf(ficresphtm,"</tr>\n");
        !          4701:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
        !          4702:          if(iage <= iagemax)
        !          4703:            fprintf(ficresp,"\n");
1.240     brouard  4704:        }
1.251     brouard  4705:        if(first==1)
                   4706:          printf("Others in log...\n");
                   4707:        fprintf(ficlog,"\n");
                   4708:       } /* end loop age iage */
1.265   ! brouard  4709:       
1.251     brouard  4710:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265   ! brouard  4711:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4712:        if(posproptt < 1.e-5){
1.265   ! brouard  4713:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4714:        }else{
1.265   ! brouard  4715:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4716:        }
1.226     brouard  4717:       }
1.251     brouard  4718:       fprintf(ficresphtm,"</tr>\n");
                   4719:       fprintf(ficresphtm,"</table>\n");
                   4720:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4721:       if(posproptt < 1.e-5){
1.251     brouard  4722:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4723:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4724:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4725:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4726:        invalidvarcomb[j1]=1;
1.226     brouard  4727:       }else{
1.251     brouard  4728:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4729:        invalidvarcomb[j1]=0;
1.226     brouard  4730:       }
1.251     brouard  4731:       fprintf(ficresphtmfr,"</table>\n");
                   4732:       fprintf(ficlog,"\n");
                   4733:       if(j!=0){
                   4734:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265   ! brouard  4735:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4736:          for(k=1; k <=(nlstate+ndeath); k++){
                   4737:            if (k != i) {
1.265   ! brouard  4738:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4739:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4740:                  if(j1==1){ /* All dummy covariates to zero */
                   4741:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4742:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4743:                    printf("%d%d ",i,k);
                   4744:                    fprintf(ficlog,"%d%d ",i,k);
1.265   ! brouard  4745:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
        !          4746:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
        !          4747:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4748:                  }
1.253     brouard  4749:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4750:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4751:                    x[iage]= (double)iage;
                   4752:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265   ! brouard  4753:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4754:                  }
                   4755:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265   ! brouard  4756:                  pstart[s1]=b;
        !          4757:                  pstart[s1-1]=a;
1.252     brouard  4758:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4759:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4760:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265   ! brouard  4761:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4762:                  printf("%d%d ",i,k);
                   4763:                  fprintf(ficlog,"%d%d ",i,k);
1.265   ! brouard  4764:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4765:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4766:                  ;
                   4767:                }
                   4768:                /* printf("%12.7f )", param[i][jj][k]); */
                   4769:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265   ! brouard  4770:                s1++; 
1.251     brouard  4771:              } /* end jj */
                   4772:            } /* end k!= i */
                   4773:          } /* end k */
1.265   ! brouard  4774:        } /* end i, s1 */
1.251     brouard  4775:       } /* end j !=0 */
                   4776:     } /* end selected combination of covariate j1 */
                   4777:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4778:       printf("#Freqsummary: Starting values for the constants:\n");
                   4779:       fprintf(ficlog,"\n");
1.265   ! brouard  4780:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4781:        for(k=1; k <=(nlstate+ndeath); k++){
                   4782:          if (k != i) {
                   4783:            printf("%d%d ",i,k);
                   4784:            fprintf(ficlog,"%d%d ",i,k);
                   4785:            for(jj=1; jj <=ncovmodel; jj++){
1.265   ! brouard  4786:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4787:              if(jj==1){ /* Age has to be done */
1.265   ! brouard  4788:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
        !          4789:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
        !          4790:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4791:              }
                   4792:              /* printf("%12.7f )", param[i][jj][k]); */
                   4793:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265   ! brouard  4794:              s1++; 
1.250     brouard  4795:            }
1.251     brouard  4796:            printf("\n");
                   4797:            fprintf(ficlog,"\n");
1.250     brouard  4798:          }
                   4799:        }
                   4800:       }
1.251     brouard  4801:       printf("#Freqsummary\n");
                   4802:       fprintf(ficlog,"\n");
1.265   ! brouard  4803:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
        !          4804:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
        !          4805:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
        !          4806:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
        !          4807:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
        !          4808:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
        !          4809:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
        !          4810:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4811:          /* } */
                   4812:        }
1.265   ! brouard  4813:       } /* end loop s1 */
1.251     brouard  4814:       
                   4815:       printf("\n");
                   4816:       fprintf(ficlog,"\n");
                   4817:     } /* end j=0 */
1.249     brouard  4818:   } /* end j */
1.252     brouard  4819: 
1.253     brouard  4820:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4821:     for(i=1, jk=1; i <=nlstate; i++){
                   4822:       for(j=1; j <=nlstate+ndeath; j++){
                   4823:        if(j!=i){
                   4824:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4825:          printf("%1d%1d",i,j);
                   4826:          fprintf(ficparo,"%1d%1d",i,j);
                   4827:          for(k=1; k<=ncovmodel;k++){
                   4828:            /*    printf(" %lf",param[i][j][k]); */
                   4829:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4830:            p[jk]=pstart[jk];
                   4831:            printf(" %f ",pstart[jk]);
                   4832:            fprintf(ficparo," %f ",pstart[jk]);
                   4833:            jk++;
                   4834:          }
                   4835:          printf("\n");
                   4836:          fprintf(ficparo,"\n");
                   4837:        }
                   4838:       }
                   4839:     }
                   4840:   } /* end mle=-2 */
1.226     brouard  4841:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4842:   
1.226     brouard  4843:   fclose(ficresp);
                   4844:   fclose(ficresphtm);
                   4845:   fclose(ficresphtmfr);
                   4846:   free_vector(meanq,1,nqfveff);
                   4847:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4848:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4849:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4850:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4851:   free_vector(pospropt,1,nlstate);
                   4852:   free_vector(posprop,1,nlstate);
1.251     brouard  4853:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4854:   free_vector(pp,1,nlstate);
                   4855:   /* End of freqsummary */
                   4856: }
1.126     brouard  4857: 
                   4858: /************ Prevalence ********************/
1.227     brouard  4859: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4860: {  
                   4861:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4862:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4863:      We still use firstpass and lastpass as another selection.
                   4864:   */
1.126     brouard  4865:  
1.227     brouard  4866:   int i, m, jk, j1, bool, z1,j, iv;
                   4867:   int mi; /* Effective wave */
                   4868:   int iage;
                   4869:   double agebegin, ageend;
                   4870: 
                   4871:   double **prop;
                   4872:   double posprop; 
                   4873:   double  y2; /* in fractional years */
                   4874:   int iagemin, iagemax;
                   4875:   int first; /** to stop verbosity which is redirected to log file */
                   4876: 
                   4877:   iagemin= (int) agemin;
                   4878:   iagemax= (int) agemax;
                   4879:   /*pp=vector(1,nlstate);*/
1.251     brouard  4880:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4881:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4882:   j1=0;
1.222     brouard  4883:   
1.227     brouard  4884:   /*j=cptcoveff;*/
                   4885:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4886:   
1.227     brouard  4887:   first=1;
                   4888:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4889:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4890:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4891:        prop[i][iage]=0.0;
                   4892:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4893:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4894:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4895:     
                   4896:     for (i=1; i<=imx; i++) { /* Each individual */
                   4897:       bool=1;
                   4898:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4899:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4900:        m=mw[mi][i];
                   4901:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4902:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4903:        for (z1=1; z1<=cptcoveff; z1++){
                   4904:          if( Fixed[Tmodelind[z1]]==1){
                   4905:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4906:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4907:              bool=0;
                   4908:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4909:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4910:              bool=0;
                   4911:            }
                   4912:        }
                   4913:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4914:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4915:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4916:          if(m >=firstpass && m <=lastpass){
                   4917:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4918:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4919:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4920:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4921:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4922:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4923:                exit(1);
                   4924:              }
                   4925:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4926:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4927:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4928:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4929:              } /* end valid statuses */ 
                   4930:            } /* end selection of dates */
                   4931:          } /* end selection of waves */
                   4932:        } /* end bool */
                   4933:       } /* end wave */
                   4934:     } /* end individual */
                   4935:     for(i=iagemin; i <= iagemax+3; i++){  
                   4936:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4937:        posprop += prop[jk][i]; 
                   4938:       } 
                   4939:       
                   4940:       for(jk=1; jk <=nlstate ; jk++){      
                   4941:        if( i <=  iagemax){ 
                   4942:          if(posprop>=1.e-5){ 
                   4943:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4944:          } else{
                   4945:            if(first==1){
                   4946:              first=0;
                   4947:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4948:            }
                   4949:          }
                   4950:        } 
                   4951:       }/* end jk */ 
                   4952:     }/* end i */ 
1.222     brouard  4953:      /*} *//* end i1 */
1.227     brouard  4954:   } /* end j1 */
1.222     brouard  4955:   
1.227     brouard  4956:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4957:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4958:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4959: }  /* End of prevalence */
1.126     brouard  4960: 
                   4961: /************* Waves Concatenation ***************/
                   4962: 
                   4963: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4964: {
                   4965:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4966:      Death is a valid wave (if date is known).
                   4967:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4968:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4969:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4970:   */
1.126     brouard  4971: 
1.224     brouard  4972:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4973:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4974:      double sum=0., jmean=0.;*/
1.224     brouard  4975:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4976:   int j, k=0,jk, ju, jl;
                   4977:   double sum=0.;
                   4978:   first=0;
1.214     brouard  4979:   firstwo=0;
1.217     brouard  4980:   firsthree=0;
1.218     brouard  4981:   firstfour=0;
1.164     brouard  4982:   jmin=100000;
1.126     brouard  4983:   jmax=-1;
                   4984:   jmean=0.;
1.224     brouard  4985: 
                   4986: /* Treating live states */
1.214     brouard  4987:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4988:     mi=0;  /* First valid wave */
1.227     brouard  4989:     mli=0; /* Last valid wave */
1.126     brouard  4990:     m=firstpass;
1.214     brouard  4991:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4992:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4993:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4994:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4995:        mw[++mi][i]=m;
                   4996:        mli=m;
1.224     brouard  4997:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4998:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4999:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5000:       }
1.227     brouard  5001:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5002: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5003:        break;
1.224     brouard  5004: #else
1.227     brouard  5005:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5006:          if(firsthree == 0){
1.262     brouard  5007:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5008:            firsthree=1;
                   5009:          }
1.262     brouard  5010:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5011:          mw[++mi][i]=m;
                   5012:          mli=m;
                   5013:        }
                   5014:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5015:          nbwarn++;
                   5016:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5017:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5018:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5019:          }
                   5020:          break;
                   5021:        }
                   5022:        break;
1.224     brouard  5023: #endif
1.227     brouard  5024:       }/* End m >= lastpass */
1.126     brouard  5025:     }/* end while */
1.224     brouard  5026: 
1.227     brouard  5027:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5028:     /* After last pass */
1.224     brouard  5029: /* Treating death states */
1.214     brouard  5030:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5031:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5032:       /* } */
1.126     brouard  5033:       mi++;    /* Death is another wave */
                   5034:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5035:       /* Only death is a correct wave */
1.126     brouard  5036:       mw[mi][i]=m;
1.257     brouard  5037:     } /* else not in a death state */
1.224     brouard  5038: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5039:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5040:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5041:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5042:          nbwarn++;
                   5043:          if(firstfiv==0){
                   5044:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5045:            firstfiv=1;
                   5046:          }else{
                   5047:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5048:          }
                   5049:        }else{ /* Death occured afer last wave potential bias */
                   5050:          nberr++;
                   5051:          if(firstwo==0){
1.257     brouard  5052:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5053:            firstwo=1;
                   5054:          }
1.257     brouard  5055:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5056:        }
1.257     brouard  5057:       }else{ /* if date of interview is unknown */
1.227     brouard  5058:        /* death is known but not confirmed by death status at any wave */
                   5059:        if(firstfour==0){
                   5060:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5061:          firstfour=1;
                   5062:        }
                   5063:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5064:       }
1.224     brouard  5065:     } /* end if date of death is known */
                   5066: #endif
                   5067:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5068:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5069:     if(mi==0){
                   5070:       nbwarn++;
                   5071:       if(first==0){
1.227     brouard  5072:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5073:        first=1;
1.126     brouard  5074:       }
                   5075:       if(first==1){
1.227     brouard  5076:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5077:       }
                   5078:     } /* end mi==0 */
                   5079:   } /* End individuals */
1.214     brouard  5080:   /* wav and mw are no more changed */
1.223     brouard  5081:        
1.214     brouard  5082:   
1.126     brouard  5083:   for(i=1; i<=imx; i++){
                   5084:     for(mi=1; mi<wav[i];mi++){
                   5085:       if (stepm <=0)
1.227     brouard  5086:        dh[mi][i]=1;
1.126     brouard  5087:       else{
1.260     brouard  5088:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5089:          if (agedc[i] < 2*AGESUP) {
                   5090:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5091:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5092:            else if(j<0){
                   5093:              nberr++;
                   5094:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5095:              j=1; /* Temporary Dangerous patch */
                   5096:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5097:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5098:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5099:            }
                   5100:            k=k+1;
                   5101:            if (j >= jmax){
                   5102:              jmax=j;
                   5103:              ijmax=i;
                   5104:            }
                   5105:            if (j <= jmin){
                   5106:              jmin=j;
                   5107:              ijmin=i;
                   5108:            }
                   5109:            sum=sum+j;
                   5110:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5111:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5112:          }
                   5113:        }
                   5114:        else{
                   5115:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5116: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5117:                                        
1.227     brouard  5118:          k=k+1;
                   5119:          if (j >= jmax) {
                   5120:            jmax=j;
                   5121:            ijmax=i;
                   5122:          }
                   5123:          else if (j <= jmin){
                   5124:            jmin=j;
                   5125:            ijmin=i;
                   5126:          }
                   5127:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5128:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5129:          if(j<0){
                   5130:            nberr++;
                   5131:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5132:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5133:          }
                   5134:          sum=sum+j;
                   5135:        }
                   5136:        jk= j/stepm;
                   5137:        jl= j -jk*stepm;
                   5138:        ju= j -(jk+1)*stepm;
                   5139:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5140:          if(jl==0){
                   5141:            dh[mi][i]=jk;
                   5142:            bh[mi][i]=0;
                   5143:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5144:                  * to avoid the price of an extra matrix product in likelihood */
                   5145:            dh[mi][i]=jk+1;
                   5146:            bh[mi][i]=ju;
                   5147:          }
                   5148:        }else{
                   5149:          if(jl <= -ju){
                   5150:            dh[mi][i]=jk;
                   5151:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5152:                                 * is higher than the multiple of stepm and negative otherwise.
                   5153:                                 */
                   5154:          }
                   5155:          else{
                   5156:            dh[mi][i]=jk+1;
                   5157:            bh[mi][i]=ju;
                   5158:          }
                   5159:          if(dh[mi][i]==0){
                   5160:            dh[mi][i]=1; /* At least one step */
                   5161:            bh[mi][i]=ju; /* At least one step */
                   5162:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5163:          }
                   5164:        } /* end if mle */
1.126     brouard  5165:       }
                   5166:     } /* end wave */
                   5167:   }
                   5168:   jmean=sum/k;
                   5169:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5170:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5171: }
1.126     brouard  5172: 
                   5173: /*********** Tricode ****************************/
1.220     brouard  5174:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5175:  {
                   5176:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5177:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5178:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5179:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5180:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5181:     */
1.130     brouard  5182: 
1.242     brouard  5183:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5184:    int modmaxcovj=0; /* Modality max of covariates j */
                   5185:    int cptcode=0; /* Modality max of covariates j */
                   5186:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5187: 
                   5188: 
1.242     brouard  5189:    /* cptcoveff=0;  */
                   5190:    /* *cptcov=0; */
1.126     brouard  5191:  
1.242     brouard  5192:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5193: 
1.242     brouard  5194:    /* Loop on covariates without age and products and no quantitative variable */
                   5195:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5196:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5197:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5198:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5199:        switch(Fixed[k]) {
                   5200:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5201:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5202:           ij=(int)(covar[Tvar[k]][i]);
                   5203:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5204:            * If product of Vn*Vm, still boolean *:
                   5205:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5206:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5207:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5208:              modality of the nth covariate of individual i. */
                   5209:           if (ij > modmaxcovj)
                   5210:             modmaxcovj=ij; 
                   5211:           else if (ij < modmincovj) 
                   5212:             modmincovj=ij; 
                   5213:           if ((ij < -1) && (ij > NCOVMAX)){
                   5214:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5215:             exit(1);
                   5216:           }else
                   5217:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5218:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5219:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5220:           /* getting the maximum value of the modality of the covariate
                   5221:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5222:              female ies 1, then modmaxcovj=1.
                   5223:           */
                   5224:         } /* end for loop on individuals i */
                   5225:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5226:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5227:         cptcode=modmaxcovj;
                   5228:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5229:         /*for (i=0; i<=cptcode; i++) {*/
                   5230:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5231:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5232:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5233:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5234:             if( j != -1){
                   5235:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5236:                                  covariate for which somebody answered excluding 
                   5237:                                  undefined. Usually 2: 0 and 1. */
                   5238:             }
                   5239:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5240:                                     covariate for which somebody answered including 
                   5241:                                     undefined. Usually 3: -1, 0 and 1. */
                   5242:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5243:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5244:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5245:                        
1.242     brouard  5246:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5247:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5248:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5249:         /* modmincovj=3; modmaxcovj = 7; */
                   5250:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5251:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5252:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5253:         /* nbcode[Tvar[j]][ij]=k; */
                   5254:         /* nbcode[Tvar[j]][1]=0; */
                   5255:         /* nbcode[Tvar[j]][2]=1; */
                   5256:         /* nbcode[Tvar[j]][3]=2; */
                   5257:         /* To be continued (not working yet). */
                   5258:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5259:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5260:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5261:             break;
                   5262:           }
                   5263:           ij++;
                   5264:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5265:           cptcode = ij; /* New max modality for covar j */
                   5266:         } /* end of loop on modality i=-1 to 1 or more */
                   5267:         break;
                   5268:        case 1: /* Testing on varying covariate, could be simple and
                   5269:                * should look at waves or product of fixed *
                   5270:                * varying. No time to test -1, assuming 0 and 1 only */
                   5271:         ij=0;
                   5272:         for(i=0; i<=1;i++){
                   5273:           nbcode[Tvar[k]][++ij]=i;
                   5274:         }
                   5275:         break;
                   5276:        default:
                   5277:         break;
                   5278:        } /* end switch */
                   5279:      } /* end dummy test */
                   5280:     
                   5281:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5282:      /*        /\*recode from 0 *\/ */
                   5283:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5284:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5285:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5286:      /*        } */
                   5287:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5288:      /*        if (ij > ncodemax[j]) { */
                   5289:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5290:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5291:      /*          break; */
                   5292:      /*        } */
                   5293:      /*   }  /\* end of loop on modality k *\/ */
                   5294:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5295:   
                   5296:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5297:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5298:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5299:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5300:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5301:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5302:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5303:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5304:   
                   5305:    ij=0;
                   5306:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5307:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5308:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5309:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5310:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5311:        /* If product not in single variable we don't print results */
                   5312:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5313:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5314:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5315:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5316:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5317:        if(Fixed[k]!=0)
                   5318:         anyvaryingduminmodel=1;
                   5319:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5320:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5321:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5322:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5323:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5324:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5325:      } 
                   5326:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5327:    /* ij--; */
                   5328:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5329:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5330:                * because they can be excluded from the model and real
                   5331:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5332:    for(j=ij+1; j<= cptcovt; j++){
                   5333:      Tvaraff[j]=0;
                   5334:      Tmodelind[j]=0;
                   5335:    }
                   5336:    for(j=ntveff+1; j<= cptcovt; j++){
                   5337:      TmodelInvind[j]=0;
                   5338:    }
                   5339:    /* To be sorted */
                   5340:    ;
                   5341:  }
1.126     brouard  5342: 
1.145     brouard  5343: 
1.126     brouard  5344: /*********** Health Expectancies ****************/
                   5345: 
1.235     brouard  5346:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5347: 
                   5348: {
                   5349:   /* Health expectancies, no variances */
1.164     brouard  5350:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5351:   int nhstepma, nstepma; /* Decreasing with age */
                   5352:   double age, agelim, hf;
                   5353:   double ***p3mat;
                   5354:   double eip;
                   5355: 
1.238     brouard  5356:   /* pstamp(ficreseij); */
1.126     brouard  5357:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5358:   fprintf(ficreseij,"# Age");
                   5359:   for(i=1; i<=nlstate;i++){
                   5360:     for(j=1; j<=nlstate;j++){
                   5361:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5362:     }
                   5363:     fprintf(ficreseij," e%1d. ",i);
                   5364:   }
                   5365:   fprintf(ficreseij,"\n");
                   5366: 
                   5367:   
                   5368:   if(estepm < stepm){
                   5369:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5370:   }
                   5371:   else  hstepm=estepm;   
                   5372:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5373:    * This is mainly to measure the difference between two models: for example
                   5374:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5375:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5376:    * progression in between and thus overestimating or underestimating according
                   5377:    * to the curvature of the survival function. If, for the same date, we 
                   5378:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5379:    * to compare the new estimate of Life expectancy with the same linear 
                   5380:    * hypothesis. A more precise result, taking into account a more precise
                   5381:    * curvature will be obtained if estepm is as small as stepm. */
                   5382: 
                   5383:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5384:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5385:      nhstepm is the number of hstepm from age to agelim 
                   5386:      nstepm is the number of stepm from age to agelin. 
                   5387:      Look at hpijx to understand the reason of that which relies in memory size
                   5388:      and note for a fixed period like estepm months */
                   5389:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5390:      survival function given by stepm (the optimization length). Unfortunately it
                   5391:      means that if the survival funtion is printed only each two years of age and if
                   5392:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5393:      results. So we changed our mind and took the option of the best precision.
                   5394:   */
                   5395:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5396: 
                   5397:   agelim=AGESUP;
                   5398:   /* If stepm=6 months */
                   5399:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5400:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5401:     
                   5402: /* nhstepm age range expressed in number of stepm */
                   5403:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5404:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5405:   /* if (stepm >= YEARM) hstepm=1;*/
                   5406:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5407:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5408: 
                   5409:   for (age=bage; age<=fage; age ++){ 
                   5410:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5411:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5412:     /* if (stepm >= YEARM) hstepm=1;*/
                   5413:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5414: 
                   5415:     /* If stepm=6 months */
                   5416:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5417:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5418:     
1.235     brouard  5419:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5420:     
                   5421:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5422:     
                   5423:     printf("%d|",(int)age);fflush(stdout);
                   5424:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5425:     
                   5426:     /* Computing expectancies */
                   5427:     for(i=1; i<=nlstate;i++)
                   5428:       for(j=1; j<=nlstate;j++)
                   5429:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5430:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5431:          
                   5432:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5433: 
                   5434:        }
                   5435: 
                   5436:     fprintf(ficreseij,"%3.0f",age );
                   5437:     for(i=1; i<=nlstate;i++){
                   5438:       eip=0;
                   5439:       for(j=1; j<=nlstate;j++){
                   5440:        eip +=eij[i][j][(int)age];
                   5441:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5442:       }
                   5443:       fprintf(ficreseij,"%9.4f", eip );
                   5444:     }
                   5445:     fprintf(ficreseij,"\n");
                   5446:     
                   5447:   }
                   5448:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5449:   printf("\n");
                   5450:   fprintf(ficlog,"\n");
                   5451:   
                   5452: }
                   5453: 
1.235     brouard  5454:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5455: 
                   5456: {
                   5457:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5458:      to initial status i, ei. .
1.126     brouard  5459:   */
                   5460:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5461:   int nhstepma, nstepma; /* Decreasing with age */
                   5462:   double age, agelim, hf;
                   5463:   double ***p3matp, ***p3matm, ***varhe;
                   5464:   double **dnewm,**doldm;
                   5465:   double *xp, *xm;
                   5466:   double **gp, **gm;
                   5467:   double ***gradg, ***trgradg;
                   5468:   int theta;
                   5469: 
                   5470:   double eip, vip;
                   5471: 
                   5472:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5473:   xp=vector(1,npar);
                   5474:   xm=vector(1,npar);
                   5475:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5476:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5477:   
                   5478:   pstamp(ficresstdeij);
                   5479:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5480:   fprintf(ficresstdeij,"# Age");
                   5481:   for(i=1; i<=nlstate;i++){
                   5482:     for(j=1; j<=nlstate;j++)
                   5483:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5484:     fprintf(ficresstdeij," e%1d. ",i);
                   5485:   }
                   5486:   fprintf(ficresstdeij,"\n");
                   5487: 
                   5488:   pstamp(ficrescveij);
                   5489:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5490:   fprintf(ficrescveij,"# Age");
                   5491:   for(i=1; i<=nlstate;i++)
                   5492:     for(j=1; j<=nlstate;j++){
                   5493:       cptj= (j-1)*nlstate+i;
                   5494:       for(i2=1; i2<=nlstate;i2++)
                   5495:        for(j2=1; j2<=nlstate;j2++){
                   5496:          cptj2= (j2-1)*nlstate+i2;
                   5497:          if(cptj2 <= cptj)
                   5498:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5499:        }
                   5500:     }
                   5501:   fprintf(ficrescveij,"\n");
                   5502:   
                   5503:   if(estepm < stepm){
                   5504:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5505:   }
                   5506:   else  hstepm=estepm;   
                   5507:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5508:    * This is mainly to measure the difference between two models: for example
                   5509:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5510:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5511:    * progression in between and thus overestimating or underestimating according
                   5512:    * to the curvature of the survival function. If, for the same date, we 
                   5513:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5514:    * to compare the new estimate of Life expectancy with the same linear 
                   5515:    * hypothesis. A more precise result, taking into account a more precise
                   5516:    * curvature will be obtained if estepm is as small as stepm. */
                   5517: 
                   5518:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5519:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5520:      nhstepm is the number of hstepm from age to agelim 
                   5521:      nstepm is the number of stepm from age to agelin. 
                   5522:      Look at hpijx to understand the reason of that which relies in memory size
                   5523:      and note for a fixed period like estepm months */
                   5524:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5525:      survival function given by stepm (the optimization length). Unfortunately it
                   5526:      means that if the survival funtion is printed only each two years of age and if
                   5527:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5528:      results. So we changed our mind and took the option of the best precision.
                   5529:   */
                   5530:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5531: 
                   5532:   /* If stepm=6 months */
                   5533:   /* nhstepm age range expressed in number of stepm */
                   5534:   agelim=AGESUP;
                   5535:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5536:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5537:   /* if (stepm >= YEARM) hstepm=1;*/
                   5538:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5539:   
                   5540:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5541:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5542:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5543:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5544:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5545:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5546: 
                   5547:   for (age=bage; age<=fage; age ++){ 
                   5548:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5549:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5550:     /* if (stepm >= YEARM) hstepm=1;*/
                   5551:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5552:                
1.126     brouard  5553:     /* If stepm=6 months */
                   5554:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5555:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5556:     
                   5557:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5558:                
1.126     brouard  5559:     /* Computing  Variances of health expectancies */
                   5560:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5561:        decrease memory allocation */
                   5562:     for(theta=1; theta <=npar; theta++){
                   5563:       for(i=1; i<=npar; i++){ 
1.222     brouard  5564:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5565:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5566:       }
1.235     brouard  5567:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5568:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5569:                        
1.126     brouard  5570:       for(j=1; j<= nlstate; j++){
1.222     brouard  5571:        for(i=1; i<=nlstate; i++){
                   5572:          for(h=0; h<=nhstepm-1; h++){
                   5573:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5574:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5575:          }
                   5576:        }
1.126     brouard  5577:       }
1.218     brouard  5578:                        
1.126     brouard  5579:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5580:        for(h=0; h<=nhstepm-1; h++){
                   5581:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5582:        }
1.126     brouard  5583:     }/* End theta */
                   5584:     
                   5585:     
                   5586:     for(h=0; h<=nhstepm-1; h++)
                   5587:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5588:        for(theta=1; theta <=npar; theta++)
                   5589:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5590:     
1.218     brouard  5591:                
1.222     brouard  5592:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5593:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5594:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5595:                
1.222     brouard  5596:     printf("%d|",(int)age);fflush(stdout);
                   5597:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5598:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5599:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5600:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5601:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5602:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5603:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5604:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5605:       }
                   5606:     }
1.218     brouard  5607:                
1.126     brouard  5608:     /* Computing expectancies */
1.235     brouard  5609:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5610:     for(i=1; i<=nlstate;i++)
                   5611:       for(j=1; j<=nlstate;j++)
1.222     brouard  5612:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5613:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5614:                                        
1.222     brouard  5615:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5616:                                        
1.222     brouard  5617:        }
1.218     brouard  5618:                
1.126     brouard  5619:     fprintf(ficresstdeij,"%3.0f",age );
                   5620:     for(i=1; i<=nlstate;i++){
                   5621:       eip=0.;
                   5622:       vip=0.;
                   5623:       for(j=1; j<=nlstate;j++){
1.222     brouard  5624:        eip += eij[i][j][(int)age];
                   5625:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5626:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5627:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5628:       }
                   5629:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5630:     }
                   5631:     fprintf(ficresstdeij,"\n");
1.218     brouard  5632:                
1.126     brouard  5633:     fprintf(ficrescveij,"%3.0f",age );
                   5634:     for(i=1; i<=nlstate;i++)
                   5635:       for(j=1; j<=nlstate;j++){
1.222     brouard  5636:        cptj= (j-1)*nlstate+i;
                   5637:        for(i2=1; i2<=nlstate;i2++)
                   5638:          for(j2=1; j2<=nlstate;j2++){
                   5639:            cptj2= (j2-1)*nlstate+i2;
                   5640:            if(cptj2 <= cptj)
                   5641:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5642:          }
1.126     brouard  5643:       }
                   5644:     fprintf(ficrescveij,"\n");
1.218     brouard  5645:                
1.126     brouard  5646:   }
                   5647:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5648:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5649:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5650:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5651:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5652:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5653:   printf("\n");
                   5654:   fprintf(ficlog,"\n");
1.218     brouard  5655:        
1.126     brouard  5656:   free_vector(xm,1,npar);
                   5657:   free_vector(xp,1,npar);
                   5658:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5659:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5660:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5661: }
1.218     brouard  5662:  
1.126     brouard  5663: /************ Variance ******************/
1.235     brouard  5664:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5665:  {
                   5666:    /* Variance of health expectancies */
                   5667:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5668:    /* double **newm;*/
                   5669:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5670:   
                   5671:    /* int movingaverage(); */
                   5672:    double **dnewm,**doldm;
                   5673:    double **dnewmp,**doldmp;
                   5674:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5675:    int k;
                   5676:    double *xp;
                   5677:    double **gp, **gm;  /* for var eij */
                   5678:    double ***gradg, ***trgradg; /*for var eij */
                   5679:    double **gradgp, **trgradgp; /* for var p point j */
                   5680:    double *gpp, *gmp; /* for var p point j */
                   5681:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5682:    double ***p3mat;
                   5683:    double age,agelim, hf;
                   5684:    /* double ***mobaverage; */
                   5685:    int theta;
                   5686:    char digit[4];
                   5687:    char digitp[25];
                   5688: 
                   5689:    char fileresprobmorprev[FILENAMELENGTH];
                   5690: 
                   5691:    if(popbased==1){
                   5692:      if(mobilav!=0)
                   5693:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5694:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5695:    }
                   5696:    else 
                   5697:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5698: 
1.218     brouard  5699:    /* if (mobilav!=0) { */
                   5700:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5701:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5702:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5703:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5704:    /*   } */
                   5705:    /* } */
                   5706: 
                   5707:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5708:    sprintf(digit,"%-d",ij);
                   5709:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5710:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5711:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5712:    strcat(fileresprobmorprev,fileresu);
                   5713:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5714:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5715:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5716:    }
                   5717:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5718:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5719:    pstamp(ficresprobmorprev);
                   5720:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5721:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5722:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5723:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5724:    }
                   5725:    for(j=1;j<=cptcoveff;j++) 
                   5726:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5727:    fprintf(ficresprobmorprev,"\n");
                   5728: 
1.218     brouard  5729:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5730:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5731:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5732:      for(i=1; i<=nlstate;i++)
                   5733:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5734:    }  
                   5735:    fprintf(ficresprobmorprev,"\n");
                   5736:   
                   5737:    fprintf(ficgp,"\n# Routine varevsij");
                   5738:    fprintf(ficgp,"\nunset title \n");
                   5739:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5740:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5741:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5742:    /*   } */
                   5743:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5744:    pstamp(ficresvij);
                   5745:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5746:    if(popbased==1)
                   5747:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5748:    else
                   5749:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5750:    fprintf(ficresvij,"# Age");
                   5751:    for(i=1; i<=nlstate;i++)
                   5752:      for(j=1; j<=nlstate;j++)
                   5753:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5754:    fprintf(ficresvij,"\n");
                   5755: 
                   5756:    xp=vector(1,npar);
                   5757:    dnewm=matrix(1,nlstate,1,npar);
                   5758:    doldm=matrix(1,nlstate,1,nlstate);
                   5759:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5760:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5761: 
                   5762:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5763:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5764:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5765:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5766:   
1.218     brouard  5767:    if(estepm < stepm){
                   5768:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5769:    }
                   5770:    else  hstepm=estepm;   
                   5771:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5772:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5773:       nhstepm is the number of hstepm from age to agelim 
                   5774:       nstepm is the number of stepm from age to agelim. 
                   5775:       Look at function hpijx to understand why because of memory size limitations, 
                   5776:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5777:       survival function given by stepm (the optimization length). Unfortunately it
                   5778:       means that if the survival funtion is printed every two years of age and if
                   5779:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5780:       results. So we changed our mind and took the option of the best precision.
                   5781:    */
                   5782:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5783:    agelim = AGESUP;
                   5784:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5785:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5786:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5787:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5788:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5789:      gp=matrix(0,nhstepm,1,nlstate);
                   5790:      gm=matrix(0,nhstepm,1,nlstate);
                   5791:                
                   5792:                
                   5793:      for(theta=1; theta <=npar; theta++){
                   5794:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5795:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5796:        }
                   5797:                        
1.242     brouard  5798:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5799:                        
                   5800:        if (popbased==1) {
                   5801:         if(mobilav ==0){
                   5802:           for(i=1; i<=nlstate;i++)
                   5803:             prlim[i][i]=probs[(int)age][i][ij];
                   5804:         }else{ /* mobilav */ 
                   5805:           for(i=1; i<=nlstate;i++)
                   5806:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5807:         }
                   5808:        }
                   5809:                        
1.235     brouard  5810:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5811:        for(j=1; j<= nlstate; j++){
                   5812:         for(h=0; h<=nhstepm; h++){
                   5813:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5814:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5815:         }
                   5816:        }
                   5817:        /* Next for computing probability of death (h=1 means
                   5818:          computed over hstepm matrices product = hstepm*stepm months) 
                   5819:          as a weighted average of prlim.
                   5820:        */
                   5821:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5822:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5823:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5824:        }    
                   5825:        /* end probability of death */
                   5826:                        
                   5827:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5828:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5829:                        
1.242     brouard  5830:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5831:                        
                   5832:        if (popbased==1) {
                   5833:         if(mobilav ==0){
                   5834:           for(i=1; i<=nlstate;i++)
                   5835:             prlim[i][i]=probs[(int)age][i][ij];
                   5836:         }else{ /* mobilav */ 
                   5837:           for(i=1; i<=nlstate;i++)
                   5838:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5839:         }
                   5840:        }
                   5841:                        
1.235     brouard  5842:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5843:                        
                   5844:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5845:         for(h=0; h<=nhstepm; h++){
                   5846:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5847:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5848:         }
                   5849:        }
                   5850:        /* This for computing probability of death (h=1 means
                   5851:          computed over hstepm matrices product = hstepm*stepm months) 
                   5852:          as a weighted average of prlim.
                   5853:        */
                   5854:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5855:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5856:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5857:        }    
                   5858:        /* end probability of death */
                   5859:                        
                   5860:        for(j=1; j<= nlstate; j++) /* vareij */
                   5861:         for(h=0; h<=nhstepm; h++){
                   5862:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5863:         }
                   5864:                        
                   5865:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5866:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5867:        }
                   5868:                        
                   5869:      } /* End theta */
                   5870:                
                   5871:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5872:                
                   5873:      for(h=0; h<=nhstepm; h++) /* veij */
                   5874:        for(j=1; j<=nlstate;j++)
                   5875:         for(theta=1; theta <=npar; theta++)
                   5876:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5877:                
                   5878:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5879:        for(theta=1; theta <=npar; theta++)
                   5880:         trgradgp[j][theta]=gradgp[theta][j];
                   5881:                
                   5882:                
                   5883:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5884:      for(i=1;i<=nlstate;i++)
                   5885:        for(j=1;j<=nlstate;j++)
                   5886:         vareij[i][j][(int)age] =0.;
                   5887:                
                   5888:      for(h=0;h<=nhstepm;h++){
                   5889:        for(k=0;k<=nhstepm;k++){
                   5890:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5891:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5892:         for(i=1;i<=nlstate;i++)
                   5893:           for(j=1;j<=nlstate;j++)
                   5894:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5895:        }
                   5896:      }
                   5897:                
                   5898:      /* pptj */
                   5899:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5900:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5901:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5902:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5903:         varppt[j][i]=doldmp[j][i];
                   5904:      /* end ppptj */
                   5905:      /*  x centered again */
                   5906:                
1.242     brouard  5907:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5908:                
                   5909:      if (popbased==1) {
                   5910:        if(mobilav ==0){
                   5911:         for(i=1; i<=nlstate;i++)
                   5912:           prlim[i][i]=probs[(int)age][i][ij];
                   5913:        }else{ /* mobilav */ 
                   5914:         for(i=1; i<=nlstate;i++)
                   5915:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5916:        }
                   5917:      }
                   5918:                
                   5919:      /* This for computing probability of death (h=1 means
                   5920:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5921:        as a weighted average of prlim.
                   5922:      */
1.235     brouard  5923:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5924:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5925:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5926:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5927:      }    
                   5928:      /* end probability of death */
                   5929:                
                   5930:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5931:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5932:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5933:        for(i=1; i<=nlstate;i++){
                   5934:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5935:        }
                   5936:      } 
                   5937:      fprintf(ficresprobmorprev,"\n");
                   5938:                
                   5939:      fprintf(ficresvij,"%.0f ",age );
                   5940:      for(i=1; i<=nlstate;i++)
                   5941:        for(j=1; j<=nlstate;j++){
                   5942:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5943:        }
                   5944:      fprintf(ficresvij,"\n");
                   5945:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5946:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5947:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5948:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5949:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5950:    } /* End age */
                   5951:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5952:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5953:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5954:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5955:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5956:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5957:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5958:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5959:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5960:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5961:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5962:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5963:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5964:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5965:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5966:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5967:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5968:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5969:     */
1.218     brouard  5970:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5971:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5972: 
1.218     brouard  5973:    free_vector(xp,1,npar);
                   5974:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5975:    free_matrix(dnewm,1,nlstate,1,npar);
                   5976:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5977:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5978:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5979:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5980:    fclose(ficresprobmorprev);
                   5981:    fflush(ficgp);
                   5982:    fflush(fichtm); 
                   5983:  }  /* end varevsij */
1.126     brouard  5984: 
                   5985: /************ Variance of prevlim ******************/
1.235     brouard  5986:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5987: {
1.205     brouard  5988:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5989:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5990: 
1.126     brouard  5991:   double **dnewm,**doldm;
                   5992:   int i, j, nhstepm, hstepm;
                   5993:   double *xp;
                   5994:   double *gp, *gm;
                   5995:   double **gradg, **trgradg;
1.208     brouard  5996:   double **mgm, **mgp;
1.126     brouard  5997:   double age,agelim;
                   5998:   int theta;
                   5999:   
                   6000:   pstamp(ficresvpl);
                   6001:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6002:   fprintf(ficresvpl,"# Age ");
                   6003:   if(nresult >=1)
                   6004:     fprintf(ficresvpl," Result# ");
1.126     brouard  6005:   for(i=1; i<=nlstate;i++)
                   6006:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6007:   fprintf(ficresvpl,"\n");
                   6008: 
                   6009:   xp=vector(1,npar);
                   6010:   dnewm=matrix(1,nlstate,1,npar);
                   6011:   doldm=matrix(1,nlstate,1,nlstate);
                   6012:   
                   6013:   hstepm=1*YEARM; /* Every year of age */
                   6014:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6015:   agelim = AGESUP;
                   6016:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6017:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6018:     if (stepm >= YEARM) hstepm=1;
                   6019:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6020:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6021:     mgp=matrix(1,npar,1,nlstate);
                   6022:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6023:     gp=vector(1,nlstate);
                   6024:     gm=vector(1,nlstate);
                   6025: 
                   6026:     for(theta=1; theta <=npar; theta++){
                   6027:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6028:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6029:       }
1.209     brouard  6030:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6031:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6032:       else
1.235     brouard  6033:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6034:       for(i=1;i<=nlstate;i++){
1.126     brouard  6035:        gp[i] = prlim[i][i];
1.208     brouard  6036:        mgp[theta][i] = prlim[i][i];
                   6037:       }
1.126     brouard  6038:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6039:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6040:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6041:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6042:       else
1.235     brouard  6043:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6044:       for(i=1;i<=nlstate;i++){
1.126     brouard  6045:        gm[i] = prlim[i][i];
1.208     brouard  6046:        mgm[theta][i] = prlim[i][i];
                   6047:       }
1.126     brouard  6048:       for(i=1;i<=nlstate;i++)
                   6049:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6050:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6051:     } /* End theta */
                   6052: 
                   6053:     trgradg =matrix(1,nlstate,1,npar);
                   6054: 
                   6055:     for(j=1; j<=nlstate;j++)
                   6056:       for(theta=1; theta <=npar; theta++)
                   6057:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6058:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6059:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6060:     /*   for(j=1; j<=nlstate;j++){ */
                   6061:     /*         printf(" %d ",j); */
                   6062:     /*         for(theta=1; theta <=npar; theta++) */
                   6063:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6064:     /*         printf("\n "); */
                   6065:     /*   } */
                   6066:     /* } */
                   6067:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6068:     /*   printf("\n gradg %d ",(int)age); */
                   6069:     /*   for(j=1; j<=nlstate;j++){ */
                   6070:     /*         printf("%d ",j); */
                   6071:     /*         for(theta=1; theta <=npar; theta++) */
                   6072:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6073:     /*         printf("\n "); */
                   6074:     /*   } */
                   6075:     /* } */
1.126     brouard  6076: 
                   6077:     for(i=1;i<=nlstate;i++)
                   6078:       varpl[i][(int)age] =0.;
1.209     brouard  6079:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6080:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6081:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6082:     }else{
1.126     brouard  6083:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6084:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6085:     }
1.126     brouard  6086:     for(i=1;i<=nlstate;i++)
                   6087:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6088: 
                   6089:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6090:     if(nresult >=1)
                   6091:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6092:     for(i=1; i<=nlstate;i++)
                   6093:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6094:     fprintf(ficresvpl,"\n");
                   6095:     free_vector(gp,1,nlstate);
                   6096:     free_vector(gm,1,nlstate);
1.208     brouard  6097:     free_matrix(mgm,1,npar,1,nlstate);
                   6098:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6099:     free_matrix(gradg,1,npar,1,nlstate);
                   6100:     free_matrix(trgradg,1,nlstate,1,npar);
                   6101:   } /* End age */
                   6102: 
                   6103:   free_vector(xp,1,npar);
                   6104:   free_matrix(doldm,1,nlstate,1,npar);
                   6105:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6106: 
                   6107: }
                   6108: 
                   6109: /************ Variance of one-step probabilities  ******************/
                   6110: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6111:  {
                   6112:    int i, j=0,  k1, l1, tj;
                   6113:    int k2, l2, j1,  z1;
                   6114:    int k=0, l;
                   6115:    int first=1, first1, first2;
                   6116:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6117:    double **dnewm,**doldm;
                   6118:    double *xp;
                   6119:    double *gp, *gm;
                   6120:    double **gradg, **trgradg;
                   6121:    double **mu;
                   6122:    double age, cov[NCOVMAX+1];
                   6123:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6124:    int theta;
                   6125:    char fileresprob[FILENAMELENGTH];
                   6126:    char fileresprobcov[FILENAMELENGTH];
                   6127:    char fileresprobcor[FILENAMELENGTH];
                   6128:    double ***varpij;
                   6129: 
                   6130:    strcpy(fileresprob,"PROB_"); 
                   6131:    strcat(fileresprob,fileres);
                   6132:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6133:      printf("Problem with resultfile: %s\n", fileresprob);
                   6134:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6135:    }
                   6136:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6137:    strcat(fileresprobcov,fileresu);
                   6138:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6139:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6140:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6141:    }
                   6142:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6143:    strcat(fileresprobcor,fileresu);
                   6144:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6145:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6146:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6147:    }
                   6148:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6149:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6150:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6151:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6152:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6153:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6154:    pstamp(ficresprob);
                   6155:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6156:    fprintf(ficresprob,"# Age");
                   6157:    pstamp(ficresprobcov);
                   6158:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6159:    fprintf(ficresprobcov,"# Age");
                   6160:    pstamp(ficresprobcor);
                   6161:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6162:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6163: 
                   6164: 
1.222     brouard  6165:    for(i=1; i<=nlstate;i++)
                   6166:      for(j=1; j<=(nlstate+ndeath);j++){
                   6167:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6168:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6169:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6170:      }  
                   6171:    /* fprintf(ficresprob,"\n");
                   6172:       fprintf(ficresprobcov,"\n");
                   6173:       fprintf(ficresprobcor,"\n");
                   6174:    */
                   6175:    xp=vector(1,npar);
                   6176:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6177:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6178:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6179:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6180:    first=1;
                   6181:    fprintf(ficgp,"\n# Routine varprob");
                   6182:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6183:    fprintf(fichtm,"\n");
                   6184: 
                   6185:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6186:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6187:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6188: and drawn. It helps understanding how is the covariance between two incidences.\
                   6189:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6190:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6191: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6192: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6193: standard deviations wide on each axis. <br>\
                   6194:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6195:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6196: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6197: 
1.222     brouard  6198:    cov[1]=1;
                   6199:    /* tj=cptcoveff; */
1.225     brouard  6200:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6201:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6202:    j1=0;
1.224     brouard  6203:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6204:      if  (cptcovn>0) {
                   6205:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6206:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6207:        fprintf(ficresprob, "**********\n#\n");
                   6208:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6209:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6210:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6211:                        
1.222     brouard  6212:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6213:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6214:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6215:                        
                   6216:                        
1.222     brouard  6217:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6218:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6219:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6220:                        
1.222     brouard  6221:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6222:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6223:        fprintf(ficresprobcor, "**********\n#");    
                   6224:        if(invalidvarcomb[j1]){
                   6225:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6226:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6227:         continue;
                   6228:        }
                   6229:      }
                   6230:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6231:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6232:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6233:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6234:      for (age=bage; age<=fage; age ++){ 
                   6235:        cov[2]=age;
                   6236:        if(nagesqr==1)
                   6237:         cov[3]= age*age;
                   6238:        for (k=1; k<=cptcovn;k++) {
                   6239:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6240:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6241:                                                                    * 1  1 1 1 1
                   6242:                                                                    * 2  2 1 1 1
                   6243:                                                                    * 3  1 2 1 1
                   6244:                                                                    */
                   6245:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6246:        }
                   6247:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6248:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6249:        for (k=1; k<=cptcovprod;k++)
                   6250:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6251:                        
                   6252:                        
1.222     brouard  6253:        for(theta=1; theta <=npar; theta++){
                   6254:         for(i=1; i<=npar; i++)
                   6255:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6256:                                
1.222     brouard  6257:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6258:                                
1.222     brouard  6259:         k=0;
                   6260:         for(i=1; i<= (nlstate); i++){
                   6261:           for(j=1; j<=(nlstate+ndeath);j++){
                   6262:             k=k+1;
                   6263:             gp[k]=pmmij[i][j];
                   6264:           }
                   6265:         }
1.220     brouard  6266:                                
1.222     brouard  6267:         for(i=1; i<=npar; i++)
                   6268:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6269:                                
1.222     brouard  6270:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6271:         k=0;
                   6272:         for(i=1; i<=(nlstate); i++){
                   6273:           for(j=1; j<=(nlstate+ndeath);j++){
                   6274:             k=k+1;
                   6275:             gm[k]=pmmij[i][j];
                   6276:           }
                   6277:         }
1.220     brouard  6278:                                
1.222     brouard  6279:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6280:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6281:        }
1.126     brouard  6282: 
1.222     brouard  6283:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6284:         for(theta=1; theta <=npar; theta++)
                   6285:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6286:                        
1.222     brouard  6287:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6288:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6289:                        
1.222     brouard  6290:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6291:                        
1.222     brouard  6292:        k=0;
                   6293:        for(i=1; i<=(nlstate); i++){
                   6294:         for(j=1; j<=(nlstate+ndeath);j++){
                   6295:           k=k+1;
                   6296:           mu[k][(int) age]=pmmij[i][j];
                   6297:         }
                   6298:        }
                   6299:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6300:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6301:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6302:                        
1.222     brouard  6303:        /*printf("\n%d ",(int)age);
                   6304:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6305:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6306:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6307:         }*/
1.220     brouard  6308:                        
1.222     brouard  6309:        fprintf(ficresprob,"\n%d ",(int)age);
                   6310:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6311:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6312:                        
1.222     brouard  6313:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6314:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6315:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6316:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6317:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6318:        }
                   6319:        i=0;
                   6320:        for (k=1; k<=(nlstate);k++){
                   6321:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6322:           i++;
                   6323:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6324:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6325:           for (j=1; j<=i;j++){
                   6326:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6327:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6328:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6329:           }
                   6330:         }
                   6331:        }/* end of loop for state */
                   6332:      } /* end of loop for age */
                   6333:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6334:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6335:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6336:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6337:     
                   6338:      /* Confidence intervalle of pij  */
                   6339:      /*
                   6340:        fprintf(ficgp,"\nunset parametric;unset label");
                   6341:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6342:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6343:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6344:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6345:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6346:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6347:      */
                   6348:                
                   6349:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6350:      first1=1;first2=2;
                   6351:      for (k2=1; k2<=(nlstate);k2++){
                   6352:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6353:         if(l2==k2) continue;
                   6354:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6355:         for (k1=1; k1<=(nlstate);k1++){
                   6356:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6357:             if(l1==k1) continue;
                   6358:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6359:             if(i<=j) continue;
                   6360:             for (age=bage; age<=fage; age ++){ 
                   6361:               if ((int)age %5==0){
                   6362:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6363:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6364:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6365:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6366:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6367:                 c12=cv12/sqrt(v1*v2);
                   6368:                 /* Computing eigen value of matrix of covariance */
                   6369:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6370:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6371:                 if ((lc2 <0) || (lc1 <0) ){
                   6372:                   if(first2==1){
                   6373:                     first1=0;
                   6374:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6375:                   }
                   6376:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6377:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6378:                   /* lc2=fabs(lc2); */
                   6379:                 }
1.220     brouard  6380:                                                                
1.222     brouard  6381:                 /* Eigen vectors */
                   6382:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6383:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6384:                 v21=(lc1-v1)/cv12*v11;
                   6385:                 v12=-v21;
                   6386:                 v22=v11;
                   6387:                 tnalp=v21/v11;
                   6388:                 if(first1==1){
                   6389:                   first1=0;
                   6390:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6391:                 }
                   6392:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6393:                 /*printf(fignu*/
                   6394:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6395:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6396:                 if(first==1){
                   6397:                   first=0;
                   6398:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6399:                   fprintf(ficgp,"\nset parametric;unset label");
                   6400:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6401:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6402:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6403:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6404: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6405:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6406:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6407:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6408:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6409:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6410:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6411:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6412:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6413:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6414:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6415:                 }else{
                   6416:                   first=0;
                   6417:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6418:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6419:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6420:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6421:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6422:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6423:                 }/* if first */
                   6424:               } /* age mod 5 */
                   6425:             } /* end loop age */
                   6426:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6427:             first=1;
                   6428:           } /*l12 */
                   6429:         } /* k12 */
                   6430:        } /*l1 */
                   6431:      }/* k1 */
                   6432:    }  /* loop on combination of covariates j1 */
                   6433:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6434:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6435:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6436:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6437:    free_vector(xp,1,npar);
                   6438:    fclose(ficresprob);
                   6439:    fclose(ficresprobcov);
                   6440:    fclose(ficresprobcor);
                   6441:    fflush(ficgp);
                   6442:    fflush(fichtmcov);
                   6443:  }
1.126     brouard  6444: 
                   6445: 
                   6446: /******************* Printing html file ***********/
1.201     brouard  6447: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6448:                  int lastpass, int stepm, int weightopt, char model[],\
                   6449:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6450:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6451:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6452:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6453:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6454: 
                   6455:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6456:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6457: </ul>");
1.237     brouard  6458:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6459: </ul>", model);
1.214     brouard  6460:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6461:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6462:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6463:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6464:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6465:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6466:    fprintf(fichtm,"\
                   6467:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6468:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6469:    fprintf(fichtm,"\
1.217     brouard  6470:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6471:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6472:    fprintf(fichtm,"\
1.126     brouard  6473:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6474:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6475:    fprintf(fichtm,"\
1.217     brouard  6476:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6477:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6478:    fprintf(fichtm,"\
1.211     brouard  6479:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6480:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6481:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6482:    if(prevfcast==1){
                   6483:      fprintf(fichtm,"\
                   6484:  - Prevalence projections by age and states:                           \
1.201     brouard  6485:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6486:    }
1.126     brouard  6487: 
                   6488: 
1.225     brouard  6489:    m=pow(2,cptcoveff);
1.222     brouard  6490:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6491: 
1.264     brouard  6492:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6493: 
                   6494:    jj1=0;
                   6495: 
                   6496:    fprintf(fichtm," \n<ul>");
                   6497:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6498:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6499:      if(m != 1 && TKresult[nres]!= k1)
                   6500:        continue;
                   6501:      jj1++;
                   6502:      if (cptcovn > 0) {
                   6503:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6504:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6505:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6506:        }
                   6507:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6508:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6509:        }
                   6510:        fprintf(fichtm,"\">");
                   6511:        
                   6512:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6513:        fprintf(fichtm,"************ Results for covariates");
                   6514:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6515:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6516:        }
                   6517:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6518:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6519:        }
                   6520:        if(invalidvarcomb[k1]){
                   6521:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6522:         continue;
                   6523:        }
                   6524:        fprintf(fichtm,"</a></li>");
                   6525:      } /* cptcovn >0 */
                   6526:    }
                   6527:      fprintf(fichtm," \n</ul>");
                   6528: 
1.222     brouard  6529:    jj1=0;
1.237     brouard  6530: 
                   6531:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6532:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6533:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6534:        continue;
1.220     brouard  6535: 
1.222     brouard  6536:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6537:      jj1++;
                   6538:      if (cptcovn > 0) {
1.264     brouard  6539:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6540:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6541:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6542:        }
                   6543:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6544:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6545:        }
                   6546:        fprintf(fichtm,"\"</a>");
                   6547:  
1.222     brouard  6548:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6549:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6550:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6551:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6552:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6553:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6554:        }
1.237     brouard  6555:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6556:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6557:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6558:       }
                   6559:        
1.230     brouard  6560:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6561:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6562:        if(invalidvarcomb[k1]){
                   6563:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6564:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6565:         continue;
                   6566:        }
                   6567:      }
                   6568:      /* aij, bij */
1.259     brouard  6569:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6570: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6571:      /* Pij */
1.241     brouard  6572:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6573: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6574:      /* Quasi-incidences */
                   6575:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6576:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6577:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6578: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6579: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6580:      /* Survival functions (period) in state j */
                   6581:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6582:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6583: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6584:      }
                   6585:      /* State specific survival functions (period) */
                   6586:      for(cpt=1; cpt<=nlstate;cpt++){
                   6587:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6588:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6589:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6590:      }
                   6591:      /* Period (stable) prevalence in each health state */
                   6592:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6593:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6594: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6595:      }
                   6596:      if(backcast==1){
                   6597:        /* Period (stable) back prevalence in each health state */
                   6598:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6599:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6600: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6601:        }
1.217     brouard  6602:      }
1.222     brouard  6603:      if(prevfcast==1){
                   6604:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6605:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6606:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6607: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6608:        }
                   6609:      }
1.220     brouard  6610:         
1.222     brouard  6611:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6612:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6613: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6614:      }
                   6615:      /* } /\* end i1 *\/ */
                   6616:    }/* End k1 */
                   6617:    fprintf(fichtm,"</ul>");
1.126     brouard  6618: 
1.222     brouard  6619:    fprintf(fichtm,"\
1.126     brouard  6620: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6621:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6622:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6623: But because parameters are usually highly correlated (a higher incidence of disability \
                   6624: and a higher incidence of recovery can give very close observed transition) it might \
                   6625: be very useful to look not only at linear confidence intervals estimated from the \
                   6626: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6627: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6628: covariance matrix of the one-step probabilities. \
                   6629: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6630: 
1.222     brouard  6631:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6632:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6633:    fprintf(fichtm,"\
1.126     brouard  6634:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6635:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6636: 
1.222     brouard  6637:    fprintf(fichtm,"\
1.126     brouard  6638:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6639:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6640:    fprintf(fichtm,"\
1.126     brouard  6641:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6642:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6643:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6644:    fprintf(fichtm,"\
1.126     brouard  6645:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6646:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6647:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6648:    fprintf(fichtm,"\
1.128     brouard  6649:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6650:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6651:    fprintf(fichtm,"\
1.128     brouard  6652:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6653:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6654:    fprintf(fichtm,"\
1.126     brouard  6655:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6656:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6657: 
                   6658: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6659: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6660: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6661: /*     <br>",fileres,fileres,fileres,fileres); */
                   6662: /*  else  */
                   6663: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6664:    fflush(fichtm);
                   6665:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6666: 
1.225     brouard  6667:    m=pow(2,cptcoveff);
1.222     brouard  6668:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6669: 
1.222     brouard  6670:    jj1=0;
1.237     brouard  6671: 
1.241     brouard  6672:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6673:    for(k1=1; k1<=m;k1++){
1.253     brouard  6674:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6675:        continue;
1.222     brouard  6676:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6677:      jj1++;
1.126     brouard  6678:      if (cptcovn > 0) {
                   6679:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6680:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6681:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6682:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6683:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6684:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6685:       }
                   6686: 
1.126     brouard  6687:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6688: 
1.222     brouard  6689:        if(invalidvarcomb[k1]){
                   6690:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6691:         continue;
                   6692:        }
1.126     brouard  6693:      }
                   6694:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6695:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6696: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6697: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6698:      }
                   6699:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6700: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6701: true period expectancies (those weighted with period prevalences are also\
                   6702:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6703:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6704: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6705:      /* } /\* end i1 *\/ */
                   6706:    }/* End k1 */
1.241     brouard  6707:   }/* End nres */
1.222     brouard  6708:    fprintf(fichtm,"</ul>");
                   6709:    fflush(fichtm);
1.126     brouard  6710: }
                   6711: 
                   6712: /******************* Gnuplot file **************/
1.223     brouard  6713: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6714: 
                   6715:   char dirfileres[132],optfileres[132];
1.264     brouard  6716:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6717:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6718:   int lv=0, vlv=0, kl=0;
1.130     brouard  6719:   int ng=0;
1.201     brouard  6720:   int vpopbased;
1.223     brouard  6721:   int ioffset; /* variable offset for columns */
1.235     brouard  6722:   int nres=0; /* Index of resultline */
1.219     brouard  6723: 
1.126     brouard  6724: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6725: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6726: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6727: /*   } */
                   6728: 
                   6729:   /*#ifdef windows */
                   6730:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6731:   /*#endif */
1.225     brouard  6732:   m=pow(2,cptcoveff);
1.126     brouard  6733: 
1.202     brouard  6734:   /* Contribution to likelihood */
                   6735:   /* Plot the probability implied in the likelihood */
1.223     brouard  6736:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6737:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6738:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6739:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6740: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6741:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6742: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6743:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6744:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6745:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6746:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6747:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6748:   for (i=1; i<= nlstate ; i ++) {
                   6749:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6750:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6751:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6752:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6753:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6754:     }
                   6755:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6756:   }
                   6757:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6758:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6759:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6760:   fprintf(ficgp,"\nset out;unset log\n");
                   6761:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6762: 
1.126     brouard  6763:   strcpy(dirfileres,optionfilefiname);
                   6764:   strcpy(optfileres,"vpl");
1.223     brouard  6765:   /* 1eme*/
1.238     brouard  6766:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6767:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6768:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6769:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6770:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6771:          continue;
                   6772:        /* We are interested in selected combination by the resultline */
1.246     brouard  6773:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6774:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  6775:        strcpy(gplotlabel,"(");
1.238     brouard  6776:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6777:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6778:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6779:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6780:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6781:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6782:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6783:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6784:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  6785:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6786:        }
                   6787:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6788:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6789:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  6790:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6791:        }
                   6792:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  6793:        /* printf("\n#\n"); */
1.238     brouard  6794:        fprintf(ficgp,"\n#\n");
                   6795:        if(invalidvarcomb[k1]){
1.260     brouard  6796:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  6797:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6798:          continue;
                   6799:        }
1.235     brouard  6800:       
1.241     brouard  6801:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6802:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  6803:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  6804:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   6805:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   6806:       /* k1-1 error should be nres-1*/
1.238     brouard  6807:        for (i=1; i<= nlstate ; i ++) {
                   6808:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6809:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6810:        }
1.260     brouard  6811:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  6812:        for (i=1; i<= nlstate ; i ++) {
                   6813:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6814:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6815:        } 
1.260     brouard  6816:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  6817:        for (i=1; i<= nlstate ; i ++) {
                   6818:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6819:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6820:        }  
1.265   ! brouard  6821:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
        !          6822:        
        !          6823:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
        !          6824:         if(cptcoveff ==0){
        !          6825:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+(cpt-1),  cpt );
        !          6826:        }else{
        !          6827:          kl=0;
        !          6828:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
        !          6829:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
        !          6830:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
        !          6831:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
        !          6832:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
        !          6833:            vlv= nbcode[Tvaraff[k]][lv];
        !          6834:            kl++;
        !          6835:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
        !          6836:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
        !          6837:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
        !          6838:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
        !          6839:            if(k==cptcoveff){
        !          6840:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
        !          6841:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
        !          6842:            }else{
        !          6843:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
        !          6844:              kl++;
        !          6845:            }
        !          6846:          } /* end covariate */
        !          6847:        } /* end if no covariate */
        !          6848: 
1.238     brouard  6849:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6850:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6851:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6852:          if(cptcoveff ==0){
1.245     brouard  6853:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6854:          }else{
                   6855:            kl=0;
                   6856:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6857:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6858:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6859:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6860:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6861:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6862:              kl++;
1.238     brouard  6863:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6864:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6865:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6866:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6867:              if(k==cptcoveff){
1.245     brouard  6868:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6869:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6870:              }else{
                   6871:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6872:                kl++;
                   6873:              }
                   6874:            } /* end covariate */
                   6875:          } /* end if no covariate */
                   6876:        } /* end if backcast */
1.264     brouard  6877:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  6878:       } /* nres */
1.201     brouard  6879:     } /* k1 */
                   6880:   } /* cpt */
1.235     brouard  6881: 
                   6882:   
1.126     brouard  6883:   /*2 eme*/
1.238     brouard  6884:   for (k1=1; k1<= m ; k1 ++){  
                   6885:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6886:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6887:        continue;
                   6888:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  6889:       strcpy(gplotlabel,"(");
1.238     brouard  6890:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6891:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6892:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6893:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6894:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6895:        vlv= nbcode[Tvaraff[k]][lv];
                   6896:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  6897:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6898:       }
1.237     brouard  6899:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6900:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6901:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6902:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  6903:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6904:       }
1.264     brouard  6905:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  6906:       fprintf(ficgp,"\n#\n");
1.223     brouard  6907:       if(invalidvarcomb[k1]){
                   6908:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6909:        continue;
                   6910:       }
1.219     brouard  6911:                        
1.241     brouard  6912:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6913:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  6914:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   6915:        if(vpopbased==0){
1.238     brouard  6916:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  6917:        }else
1.238     brouard  6918:          fprintf(ficgp,"\nreplot ");
                   6919:        for (i=1; i<= nlstate+1 ; i ++) {
                   6920:          k=2*i;
1.261     brouard  6921:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  6922:          for (j=1; j<= nlstate+1 ; j ++) {
                   6923:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6924:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6925:          }   
                   6926:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6927:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  6928:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6929:          for (j=1; j<= nlstate+1 ; j ++) {
                   6930:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6931:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6932:          }   
                   6933:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  6934:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6935:          for (j=1; j<= nlstate+1 ; j ++) {
                   6936:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6937:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6938:          }   
                   6939:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6940:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6941:        } /* state */
                   6942:       } /* vpopbased */
1.264     brouard  6943:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6944:     } /* end nres */
                   6945:   } /* k1 end 2 eme*/
                   6946:        
                   6947:        
                   6948:   /*3eme*/
                   6949:   for (k1=1; k1<= m ; k1 ++){
                   6950:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6951:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6952:        continue;
                   6953: 
                   6954:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  6955:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  6956:        strcpy(gplotlabel,"(");
1.238     brouard  6957:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6958:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6959:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6960:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6961:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6962:          vlv= nbcode[Tvaraff[k]][lv];
                   6963:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  6964:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6965:        }
                   6966:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6967:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  6968:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6969:        }       
1.264     brouard  6970:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  6971:        fprintf(ficgp,"\n#\n");
                   6972:        if(invalidvarcomb[k1]){
                   6973:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6974:          continue;
                   6975:        }
                   6976:                        
                   6977:        /*       k=2+nlstate*(2*cpt-2); */
                   6978:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6979:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  6980:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  6981:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  6982: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  6983:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6984:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6985:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6986:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6987:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6988:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6989:                                
1.238     brouard  6990:        */
                   6991:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  6992:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  6993:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6994:                                
1.238     brouard  6995:        } 
1.261     brouard  6996:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  6997:       }
1.264     brouard  6998:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  6999:     } /* end nres */
                   7000:   } /* end kl 3eme */
1.126     brouard  7001:   
1.223     brouard  7002:   /* 4eme */
1.201     brouard  7003:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7004:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7005:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7006:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7007:        continue;
1.238     brouard  7008:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7009:        strcpy(gplotlabel,"(");
1.238     brouard  7010:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7011:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7012:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7013:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7014:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7015:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7016:          vlv= nbcode[Tvaraff[k]][lv];
                   7017:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7018:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7019:        }
                   7020:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7021:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7022:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7023:        }       
1.264     brouard  7024:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7025:        fprintf(ficgp,"\n#\n");
                   7026:        if(invalidvarcomb[k1]){
                   7027:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7028:          continue;
1.223     brouard  7029:        }
1.238     brouard  7030:       
1.241     brouard  7031:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7032:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7033:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7034: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7035:        k=3;
                   7036:        for (i=1; i<= nlstate ; i ++){
                   7037:          if(i==1){
                   7038:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7039:          }else{
                   7040:            fprintf(ficgp,", '' ");
                   7041:          }
                   7042:          l=(nlstate+ndeath)*(i-1)+1;
                   7043:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7044:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7045:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7046:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7047:        } /* nlstate */
1.264     brouard  7048:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7049:       } /* end cpt state*/ 
                   7050:     } /* end nres */
                   7051:   } /* end covariate k1 */  
                   7052: 
1.220     brouard  7053: /* 5eme */
1.201     brouard  7054:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7055:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7056:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7057:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7058:        continue;
1.238     brouard  7059:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7060:        strcpy(gplotlabel,"(");
1.238     brouard  7061:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7062:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7063:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7064:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7065:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7066:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7067:          vlv= nbcode[Tvaraff[k]][lv];
                   7068:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7069:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7070:        }
                   7071:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7072:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7073:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7074:        }       
1.264     brouard  7075:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7076:        fprintf(ficgp,"\n#\n");
                   7077:        if(invalidvarcomb[k1]){
                   7078:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7079:          continue;
                   7080:        }
1.227     brouard  7081:       
1.241     brouard  7082:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7083:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7084:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7085: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7086:        k=3;
                   7087:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7088:          if(j==1)
                   7089:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7090:          else
                   7091:            fprintf(ficgp,", '' ");
                   7092:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7093:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7094:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7095:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7096:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7097:        } /* nlstate */
                   7098:        fprintf(ficgp,", '' ");
                   7099:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7100:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7101:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7102:          if(j < nlstate)
                   7103:            fprintf(ficgp,"$%d +",k+l);
                   7104:          else
                   7105:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7106:        }
1.264     brouard  7107:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7108:       } /* end cpt state*/ 
                   7109:     } /* end covariate */  
                   7110:   } /* end nres */
1.227     brouard  7111:   
1.220     brouard  7112: /* 6eme */
1.202     brouard  7113:   /* CV preval stable (period) for each covariate */
1.237     brouard  7114:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7115:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7116:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7117:       continue;
1.255     brouard  7118:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7119:       strcpy(gplotlabel,"(");      
1.211     brouard  7120:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7121:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7122:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7123:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7124:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7125:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7126:        vlv= nbcode[Tvaraff[k]][lv];
                   7127:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7128:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7129:       }
1.237     brouard  7130:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7131:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7132:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7133:       }        
1.264     brouard  7134:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7135:       fprintf(ficgp,"\n#\n");
1.223     brouard  7136:       if(invalidvarcomb[k1]){
1.227     brouard  7137:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7138:        continue;
1.223     brouard  7139:       }
1.227     brouard  7140:       
1.241     brouard  7141:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7142:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7143:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7144: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7145:       k=3; /* Offset */
1.255     brouard  7146:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7147:        if(i==1)
                   7148:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7149:        else
                   7150:          fprintf(ficgp,", '' ");
1.255     brouard  7151:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7152:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7153:        for (j=2; j<= nlstate ; j ++)
                   7154:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7155:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7156:       } /* nlstate */
1.264     brouard  7157:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7158:     } /* end cpt state*/ 
                   7159:   } /* end covariate */  
1.227     brouard  7160:   
                   7161:   
1.220     brouard  7162: /* 7eme */
1.218     brouard  7163:   if(backcast == 1){
1.217     brouard  7164:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7165:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7166:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7167:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7168:        continue;
1.255     brouard  7169:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
1.264     brouard  7170:        strcpy(gplotlabel,"(");      
                   7171:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7172:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7173:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7174:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7175:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7176:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7177:          vlv= nbcode[Tvaraff[k]][lv];
                   7178:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7179:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7180:        }
1.237     brouard  7181:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7182:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7183:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7184:        }       
1.264     brouard  7185:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7186:        fprintf(ficgp,"\n#\n");
                   7187:        if(invalidvarcomb[k1]){
                   7188:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7189:          continue;
                   7190:        }
                   7191:        
1.241     brouard  7192:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.264     brouard  7193:        fprintf(ficgp,"set label \"Ending alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7194:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7195: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7196:        k=3; /* Offset */
1.255     brouard  7197:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7198:          if(i==1)
                   7199:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7200:          else
                   7201:            fprintf(ficgp,", '' ");
                   7202:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7203:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7204:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7205:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7206:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7207:          /* for (j=2; j<= nlstate ; j ++) */
                   7208:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7209:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7210:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7211:        } /* nlstate */
1.264     brouard  7212:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7213:       } /* end cpt state*/ 
                   7214:     } /* end covariate */  
                   7215:   } /* End if backcast */
                   7216:   
1.223     brouard  7217:   /* 8eme */
1.218     brouard  7218:   if(prevfcast==1){
                   7219:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7220:     
1.237     brouard  7221:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7222:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7223:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7224:        continue;
1.211     brouard  7225:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7226:        strcpy(gplotlabel,"(");      
1.227     brouard  7227:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7228:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7229:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7230:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7231:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7232:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7233:          vlv= nbcode[Tvaraff[k]][lv];
                   7234:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7235:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7236:        }
1.237     brouard  7237:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7238:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7239:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7240:        }       
1.264     brouard  7241:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7242:        fprintf(ficgp,"\n#\n");
                   7243:        if(invalidvarcomb[k1]){
                   7244:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7245:          continue;
                   7246:        }
                   7247:        
                   7248:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7249:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7250:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7251:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7252: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7253:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7254:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7255:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7256:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7257:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7258:          if(i==1){
                   7259:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7260:          }else{
                   7261:            fprintf(ficgp,",\\\n '' ");
                   7262:          }
                   7263:          if(cptcoveff ==0){ /* No covariate */
                   7264:            ioffset=2; /* Age is in 2 */
                   7265:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7266:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7267:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7268:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7269:            fprintf(ficgp," u %d:(", ioffset); 
                   7270:            if(i==nlstate+1)
                   7271:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7272:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7273:            else
                   7274:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7275:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7276:          }else{ /* more than 2 covariates */
                   7277:            if(cptcoveff ==1){
                   7278:              ioffset=4; /* Age is in 4 */
                   7279:            }else{
                   7280:              ioffset=6; /* Age is in 6 */
                   7281:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7282:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7283:            }   
                   7284:            fprintf(ficgp," u %d:(",ioffset); 
                   7285:            kl=0;
                   7286:            strcpy(gplotcondition,"(");
                   7287:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7288:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7289:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7290:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7291:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7292:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7293:              kl++;
                   7294:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7295:              kl++;
                   7296:              if(k <cptcoveff && cptcoveff>1)
                   7297:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7298:            }
                   7299:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7300:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7301:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7302:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7303:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7304:            if(i==nlstate+1){
                   7305:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7306:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7307:            }else{
                   7308:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7309:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7310:            }
                   7311:          } /* end if covariate */
                   7312:        } /* nlstate */
1.264     brouard  7313:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7314:       } /* end cpt state*/
                   7315:     } /* end covariate */
                   7316:   } /* End if prevfcast */
1.227     brouard  7317:   
                   7318:   
1.238     brouard  7319:   /* 9eme writing MLE parameters */
                   7320:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7321:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7322:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7323:     for(k=1; k <=(nlstate+ndeath); k++){
                   7324:       if (k != i) {
1.227     brouard  7325:        fprintf(ficgp,"#   current state %d\n",k);
                   7326:        for(j=1; j <=ncovmodel; j++){
                   7327:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7328:          jk++; 
                   7329:        }
                   7330:        fprintf(ficgp,"\n");
1.126     brouard  7331:       }
                   7332:     }
1.223     brouard  7333:   }
1.187     brouard  7334:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7335:   
1.145     brouard  7336:   /*goto avoid;*/
1.238     brouard  7337:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7338:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7339:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7340:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7341:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7342:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7343:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7344:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7345:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7346:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7347:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7348:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7349:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7350:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7351:   fprintf(ficgp,"#\n");
1.223     brouard  7352:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7353:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7354:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7355:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7356:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7357:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7358:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7359:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7360:        continue;
1.264     brouard  7361:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7362:       strcpy(gplotlabel,"(");
                   7363:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7364:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7365:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7366:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7367:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7368:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7369:        vlv= nbcode[Tvaraff[k]][lv];
                   7370:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7371:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7372:       }
1.237     brouard  7373:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7374:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7375:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7376:       }        
1.264     brouard  7377:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7378:       fprintf(ficgp,"\n#\n");
1.264     brouard  7379:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7380:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7381:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7382:       if (ng==1){
                   7383:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7384:        fprintf(ficgp,"\nunset log y");
                   7385:       }else if (ng==2){
                   7386:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7387:        fprintf(ficgp,"\nset log y");
                   7388:       }else if (ng==3){
                   7389:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7390:        fprintf(ficgp,"\nset log y");
                   7391:       }else
                   7392:        fprintf(ficgp,"\nunset title ");
                   7393:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7394:       i=1;
                   7395:       for(k2=1; k2<=nlstate; k2++) {
                   7396:        k3=i;
                   7397:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7398:          if (k != k2){
                   7399:            switch( ng) {
                   7400:            case 1:
                   7401:              if(nagesqr==0)
                   7402:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7403:              else /* nagesqr =1 */
                   7404:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7405:              break;
                   7406:            case 2: /* ng=2 */
                   7407:              if(nagesqr==0)
                   7408:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7409:              else /* nagesqr =1 */
                   7410:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7411:              break;
                   7412:            case 3:
                   7413:              if(nagesqr==0)
                   7414:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7415:              else /* nagesqr =1 */
                   7416:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7417:              break;
                   7418:            }
                   7419:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7420:            ijp=1; /* product no age */
                   7421:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7422:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7423:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7424:              if(j==Tage[ij]) { /* Product by age */
                   7425:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7426:                  if(DummyV[j]==0){
1.237     brouard  7427:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7428:                  }else{ /* quantitative */
                   7429:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
1.264     brouard  7430:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.237     brouard  7431:                  }
                   7432:                  ij++;
                   7433:                }
                   7434:              }else if(j==Tprod[ijp]) { /* */ 
                   7435:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7436:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7437:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7438:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.264     brouard  7439:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
1.237     brouard  7440:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7441:                    }else{ /* Vn is dummy and Vm is quanti */
1.264     brouard  7442:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
1.237     brouard  7443:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7444:                    }
                   7445:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7446:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7447:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7448:                    }else{ /* Both quanti */
                   7449:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7450:                    }
                   7451:                  }
1.238     brouard  7452:                  ijp++;
1.237     brouard  7453:                }
                   7454:              } else{  /* simple covariate */
1.264     brouard  7455:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7456:                if(Dummy[j]==0){
                   7457:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7458:                }else{ /* quantitative */
                   7459:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7460:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7461:                }
1.237     brouard  7462:              } /* end simple */
                   7463:            } /* end j */
1.223     brouard  7464:          }else{
                   7465:            i=i-ncovmodel;
                   7466:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7467:              fprintf(ficgp," (1.");
                   7468:          }
1.227     brouard  7469:          
1.223     brouard  7470:          if(ng != 1){
                   7471:            fprintf(ficgp,")/(1");
1.227     brouard  7472:            
1.264     brouard  7473:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7474:              if(nagesqr==0)
1.264     brouard  7475:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7476:              else /* nagesqr =1 */
1.264     brouard  7477:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7478:               
1.223     brouard  7479:              ij=1;
                   7480:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7481:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7482:                  if(ij <=cptcovage) { /* Bug valgrind */
1.264     brouard  7483:                    fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7484:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7485:                    ij++;
                   7486:                  }
                   7487:                }
                   7488:                else
1.264     brouard  7489:                  fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7490:              }
                   7491:              fprintf(ficgp,")");
                   7492:            }
                   7493:            fprintf(ficgp,")");
                   7494:            if(ng ==2)
                   7495:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7496:            else /* ng= 3 */
                   7497:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7498:          }else{ /* end ng <> 1 */
                   7499:            if( k !=k2) /* logit p11 is hard to draw */
                   7500:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7501:          }
                   7502:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7503:            fprintf(ficgp,",");
                   7504:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7505:            fprintf(ficgp,",");
                   7506:          i=i+ncovmodel;
                   7507:        } /* end k */
                   7508:       } /* end k2 */
1.264     brouard  7509:       fprintf(ficgp,"\n set out; unset label;\n");
                   7510:     } /* end k1 */
1.223     brouard  7511:   } /* end ng */
                   7512:   /* avoid: */
                   7513:   fflush(ficgp); 
1.126     brouard  7514: }  /* end gnuplot */
                   7515: 
                   7516: 
                   7517: /*************** Moving average **************/
1.219     brouard  7518: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7519:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7520:    
1.222     brouard  7521:    int i, cpt, cptcod;
                   7522:    int modcovmax =1;
                   7523:    int mobilavrange, mob;
                   7524:    int iage=0;
                   7525: 
                   7526:    double sum=0.;
                   7527:    double age;
                   7528:    double *sumnewp, *sumnewm;
                   7529:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7530:   
                   7531:   
1.225     brouard  7532:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7533:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7534: 
                   7535:    sumnewp = vector(1,ncovcombmax);
                   7536:    sumnewm = vector(1,ncovcombmax);
                   7537:    agemingood = vector(1,ncovcombmax); 
                   7538:    agemaxgood = vector(1,ncovcombmax);
                   7539: 
                   7540:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7541:      sumnewm[cptcod]=0.;
                   7542:      sumnewp[cptcod]=0.;
                   7543:      agemingood[cptcod]=0;
                   7544:      agemaxgood[cptcod]=0;
                   7545:    }
                   7546:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7547:   
                   7548:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7549:      if(mobilav==1) mobilavrange=5; /* default */
                   7550:      else mobilavrange=mobilav;
                   7551:      for (age=bage; age<=fage; age++)
                   7552:        for (i=1; i<=nlstate;i++)
                   7553:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7554:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7555:      /* We keep the original values on the extreme ages bage, fage and for 
                   7556:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7557:        we use a 5 terms etc. until the borders are no more concerned. 
                   7558:      */ 
                   7559:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7560:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7561:         for (i=1; i<=nlstate;i++){
                   7562:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7563:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7564:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7565:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7566:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7567:             }
                   7568:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7569:           }
                   7570:         }
                   7571:        }/* end age */
                   7572:      }/* end mob */
                   7573:    }else
                   7574:      return -1;
                   7575:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7576:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7577:      if(invalidvarcomb[cptcod]){
                   7578:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7579:        continue;
                   7580:      }
1.219     brouard  7581: 
1.222     brouard  7582:      agemingood[cptcod]=fage-(mob-1)/2;
                   7583:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7584:        sumnewm[cptcod]=0.;
                   7585:        for (i=1; i<=nlstate;i++){
                   7586:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7587:        }
                   7588:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7589:         agemingood[cptcod]=age;
                   7590:        }else{ /* bad */
                   7591:         for (i=1; i<=nlstate;i++){
                   7592:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7593:         } /* i */
                   7594:        } /* end bad */
                   7595:      }/* age */
                   7596:      sum=0.;
                   7597:      for (i=1; i<=nlstate;i++){
                   7598:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7599:      }
                   7600:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7601:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7602:        /* for (i=1; i<=nlstate;i++){ */
                   7603:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7604:        /* } /\* i *\/ */
                   7605:      } /* end bad */
                   7606:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7607:      /* From youngest, finding the oldest wrong */
                   7608:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7609:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7610:        sumnewm[cptcod]=0.;
                   7611:        for (i=1; i<=nlstate;i++){
                   7612:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7613:        }
                   7614:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7615:         agemaxgood[cptcod]=age;
                   7616:        }else{ /* bad */
                   7617:         for (i=1; i<=nlstate;i++){
                   7618:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7619:         } /* i */
                   7620:        } /* end bad */
                   7621:      }/* age */
                   7622:      sum=0.;
                   7623:      for (i=1; i<=nlstate;i++){
                   7624:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7625:      }
                   7626:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7627:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7628:        /* for (i=1; i<=nlstate;i++){ */
                   7629:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7630:        /* } /\* i *\/ */
                   7631:      } /* end bad */
                   7632:                
                   7633:      for (age=bage; age<=fage; age++){
1.235     brouard  7634:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7635:        sumnewp[cptcod]=0.;
                   7636:        sumnewm[cptcod]=0.;
                   7637:        for (i=1; i<=nlstate;i++){
                   7638:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7639:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7640:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7641:        }
                   7642:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7643:      }
                   7644:      /* printf("\n"); */
                   7645:      /* } */
                   7646:      /* brutal averaging */
                   7647:      for (i=1; i<=nlstate;i++){
                   7648:        for (age=1; age<=bage; age++){
                   7649:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7650:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7651:        }       
                   7652:        for (age=fage; age<=AGESUP; age++){
                   7653:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7654:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7655:        }
                   7656:      } /* end i status */
                   7657:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7658:        for (age=1; age<=AGESUP; age++){
                   7659:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7660:         mobaverage[(int)age][i][cptcod]=0.;
                   7661:        }
                   7662:      }
                   7663:    }/* end cptcod */
                   7664:    free_vector(sumnewm,1, ncovcombmax);
                   7665:    free_vector(sumnewp,1, ncovcombmax);
                   7666:    free_vector(agemaxgood,1, ncovcombmax);
                   7667:    free_vector(agemingood,1, ncovcombmax);
                   7668:    return 0;
                   7669:  }/* End movingaverage */
1.218     brouard  7670:  
1.126     brouard  7671: 
                   7672: /************** Forecasting ******************/
1.235     brouard  7673:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7674:   /* proj1, year, month, day of starting projection 
                   7675:      agemin, agemax range of age
                   7676:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7677:      anproj2 year of en of projection (same day and month as proj1).
                   7678:   */
1.235     brouard  7679:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7680:   double agec; /* generic age */
                   7681:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7682:   double *popeffectif,*popcount;
                   7683:   double ***p3mat;
1.218     brouard  7684:   /* double ***mobaverage; */
1.126     brouard  7685:   char fileresf[FILENAMELENGTH];
                   7686: 
                   7687:   agelim=AGESUP;
1.211     brouard  7688:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7689:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7690:      We still use firstpass and lastpass as another selection.
                   7691:   */
1.214     brouard  7692:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7693:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7694:  
1.201     brouard  7695:   strcpy(fileresf,"F_"); 
                   7696:   strcat(fileresf,fileresu);
1.126     brouard  7697:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7698:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7699:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7700:   }
1.235     brouard  7701:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7702:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7703: 
1.225     brouard  7704:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7705: 
                   7706: 
                   7707:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7708:   if (stepm<=12) stepsize=1;
                   7709:   if(estepm < stepm){
                   7710:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7711:   }
                   7712:   else  hstepm=estepm;   
                   7713: 
                   7714:   hstepm=hstepm/stepm; 
                   7715:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7716:                                fractional in yp1 */
                   7717:   anprojmean=yp;
                   7718:   yp2=modf((yp1*12),&yp);
                   7719:   mprojmean=yp;
                   7720:   yp1=modf((yp2*30.5),&yp);
                   7721:   jprojmean=yp;
                   7722:   if(jprojmean==0) jprojmean=1;
                   7723:   if(mprojmean==0) jprojmean=1;
                   7724: 
1.227     brouard  7725:   i1=pow(2,cptcoveff);
1.126     brouard  7726:   if (cptcovn < 1){i1=1;}
                   7727:   
                   7728:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7729:   
                   7730:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7731:   
1.126     brouard  7732: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7733:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7734:   for(k=1; k<=i1;k++){
1.253     brouard  7735:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7736:       continue;
1.227     brouard  7737:     if(invalidvarcomb[k]){
                   7738:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7739:       continue;
                   7740:     }
                   7741:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7742:     for(j=1;j<=cptcoveff;j++) {
                   7743:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7744:     }
1.235     brouard  7745:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7746:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7747:     }
1.227     brouard  7748:     fprintf(ficresf," yearproj age");
                   7749:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7750:       for(i=1; i<=nlstate;i++)               
                   7751:        fprintf(ficresf," p%d%d",i,j);
                   7752:       fprintf(ficresf," wp.%d",j);
                   7753:     }
                   7754:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7755:       fprintf(ficresf,"\n");
                   7756:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7757:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7758:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7759:        nhstepm = nhstepm/hstepm; 
                   7760:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7761:        oldm=oldms;savm=savms;
1.235     brouard  7762:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7763:        
                   7764:        for (h=0; h<=nhstepm; h++){
                   7765:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7766:            fprintf(ficresf,"\n");
                   7767:            for(j=1;j<=cptcoveff;j++) 
                   7768:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7769:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7770:          } 
                   7771:          for(j=1; j<=nlstate+ndeath;j++) {
                   7772:            ppij=0.;
                   7773:            for(i=1; i<=nlstate;i++) {
                   7774:              if (mobilav==1) 
                   7775:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7776:              else {
                   7777:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7778:              }
                   7779:              if (h*hstepm/YEARM*stepm== yearp) {
                   7780:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7781:              }
                   7782:            } /* end i */
                   7783:            if (h*hstepm/YEARM*stepm==yearp) {
                   7784:              fprintf(ficresf," %.3f", ppij);
                   7785:            }
                   7786:          }/* end j */
                   7787:        } /* end h */
                   7788:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7789:       } /* end agec */
                   7790:     } /* end yearp */
                   7791:   } /* end  k */
1.219     brouard  7792:        
1.126     brouard  7793:   fclose(ficresf);
1.215     brouard  7794:   printf("End of Computing forecasting \n");
                   7795:   fprintf(ficlog,"End of Computing forecasting\n");
                   7796: 
1.126     brouard  7797: }
                   7798: 
1.218     brouard  7799: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7800: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7801: /*   /\* back1, year, month, day of starting backection  */
                   7802: /*      agemin, agemax range of age */
                   7803: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7804: /*      anback2 year of en of backection (same day and month as back1). */
                   7805: /*   *\/ */
                   7806: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7807: /*   double agec; /\* generic age *\/ */
                   7808: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7809: /*   double *popeffectif,*popcount; */
                   7810: /*   double ***p3mat; */
                   7811: /*   /\* double ***mobaverage; *\/ */
                   7812: /*   char fileresfb[FILENAMELENGTH]; */
                   7813:        
                   7814: /*   agelim=AGESUP; */
                   7815: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7816: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7817: /*      We still use firstpass and lastpass as another selection. */
                   7818: /*   *\/ */
                   7819: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7820: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7821: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7822:        
                   7823: /*   strcpy(fileresfb,"FB_");  */
                   7824: /*   strcat(fileresfb,fileresu); */
                   7825: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7826: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7827: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7828: /*   } */
                   7829: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7830: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7831:        
1.225     brouard  7832: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7833:        
                   7834: /*   /\* if (mobilav!=0) { *\/ */
                   7835: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7836: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7837: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7838: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7839: /*   /\*   } *\/ */
                   7840: /*   /\* } *\/ */
                   7841:        
                   7842: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7843: /*   if (stepm<=12) stepsize=1; */
                   7844: /*   if(estepm < stepm){ */
                   7845: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7846: /*   } */
                   7847: /*   else  hstepm=estepm;    */
                   7848:        
                   7849: /*   hstepm=hstepm/stepm;  */
                   7850: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7851: /*                                fractional in yp1 *\/ */
                   7852: /*   anprojmean=yp; */
                   7853: /*   yp2=modf((yp1*12),&yp); */
                   7854: /*   mprojmean=yp; */
                   7855: /*   yp1=modf((yp2*30.5),&yp); */
                   7856: /*   jprojmean=yp; */
                   7857: /*   if(jprojmean==0) jprojmean=1; */
                   7858: /*   if(mprojmean==0) jprojmean=1; */
                   7859:        
1.225     brouard  7860: /*   i1=cptcoveff; */
1.218     brouard  7861: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7862:   
1.218     brouard  7863: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7864:   
1.218     brouard  7865: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7866:        
                   7867: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7868: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7869: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7870: /*       k=k+1; */
                   7871: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7872: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7873: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7874: /*       } */
                   7875: /*       fprintf(ficresfb," yearbproj age"); */
                   7876: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7877: /*                             for(i=1; i<=nlstate;i++)               */
                   7878: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7879: /*                             fprintf(ficresfb," p.%d",j); */
                   7880: /*       } */
                   7881: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7882: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7883: /*                             fprintf(ficresfb,"\n"); */
                   7884: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7885: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7886: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7887: /*                                     nhstepm = nhstepm/hstepm;  */
                   7888: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7889: /*                                     oldm=oldms;savm=savms; */
                   7890: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7891: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7892: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7893: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7894: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7895: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7896: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7897: /*                                             }  */
                   7898: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7899: /*                                                     ppij=0.; */
                   7900: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7901: /*                                                             if (mobilav==1)  */
                   7902: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7903: /*                                                             else { */
                   7904: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7905: /*                                                             } */
                   7906: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7907: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7908: /*                                                             } */
                   7909: /*                                                     } /\* end i *\/ */
                   7910: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7911: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7912: /*                                                     } */
                   7913: /*                                             }/\* end j *\/ */
                   7914: /*                                     } /\* end h *\/ */
                   7915: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7916: /*                             } /\* end agec *\/ */
                   7917: /*       } /\* end yearp *\/ */
                   7918: /*     } /\* end cptcod *\/ */
                   7919: /*   } /\* end  cptcov *\/ */
                   7920:        
                   7921: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7922:        
                   7923: /*   fclose(ficresfb); */
                   7924: /*   printf("End of Computing Back forecasting \n"); */
                   7925: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7926:        
1.218     brouard  7927: /* } */
1.217     brouard  7928: 
1.126     brouard  7929: /************** Forecasting *****not tested NB*************/
1.227     brouard  7930: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7931:   
1.227     brouard  7932: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7933: /*   int *popage; */
                   7934: /*   double calagedatem, agelim, kk1, kk2; */
                   7935: /*   double *popeffectif,*popcount; */
                   7936: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7937: /*   /\* double ***mobaverage; *\/ */
                   7938: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7939: 
1.227     brouard  7940: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7941: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7942: /*   agelim=AGESUP; */
                   7943: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7944:   
1.227     brouard  7945: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7946:   
                   7947:   
1.227     brouard  7948: /*   strcpy(filerespop,"POP_");  */
                   7949: /*   strcat(filerespop,fileresu); */
                   7950: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7951: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7952: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7953: /*   } */
                   7954: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7955: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7956: 
1.227     brouard  7957: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7958: 
1.227     brouard  7959: /*   /\* if (mobilav!=0) { *\/ */
                   7960: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7961: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7962: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7963: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7964: /*   /\*   } *\/ */
                   7965: /*   /\* } *\/ */
1.126     brouard  7966: 
1.227     brouard  7967: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7968: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7969:   
1.227     brouard  7970: /*   agelim=AGESUP; */
1.126     brouard  7971:   
1.227     brouard  7972: /*   hstepm=1; */
                   7973: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7974:        
1.227     brouard  7975: /*   if (popforecast==1) { */
                   7976: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7977: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7978: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7979: /*     }  */
                   7980: /*     popage=ivector(0,AGESUP); */
                   7981: /*     popeffectif=vector(0,AGESUP); */
                   7982: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7983:     
1.227     brouard  7984: /*     i=1;    */
                   7985: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7986:     
1.227     brouard  7987: /*     imx=i; */
                   7988: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7989: /*   } */
1.218     brouard  7990:   
1.227     brouard  7991: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7992: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7993: /*       k=k+1; */
                   7994: /*       fprintf(ficrespop,"\n#******"); */
                   7995: /*       for(j=1;j<=cptcoveff;j++) { */
                   7996: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7997: /*       } */
                   7998: /*       fprintf(ficrespop,"******\n"); */
                   7999: /*       fprintf(ficrespop,"# Age"); */
                   8000: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8001: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8002:       
1.227     brouard  8003: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8004: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8005:        
1.227     brouard  8006: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8007: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8008: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8009:          
1.227     brouard  8010: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8011: /*       oldm=oldms;savm=savms; */
                   8012: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8013:          
1.227     brouard  8014: /*       for (h=0; h<=nhstepm; h++){ */
                   8015: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8016: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8017: /*         }  */
                   8018: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8019: /*           kk1=0.;kk2=0; */
                   8020: /*           for(i=1; i<=nlstate;i++) {               */
                   8021: /*             if (mobilav==1)  */
                   8022: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8023: /*             else { */
                   8024: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8025: /*             } */
                   8026: /*           } */
                   8027: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8028: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8029: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8030: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8031: /*           } */
                   8032: /*         } */
                   8033: /*         for(i=1; i<=nlstate;i++){ */
                   8034: /*           kk1=0.; */
                   8035: /*           for(j=1; j<=nlstate;j++){ */
                   8036: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8037: /*           } */
                   8038: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8039: /*         } */
1.218     brouard  8040:            
1.227     brouard  8041: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8042: /*           for(j=1; j<=nlstate;j++)  */
                   8043: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8044: /*       } */
                   8045: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8046: /*     } */
                   8047: /*       } */
1.218     brouard  8048:       
1.227     brouard  8049: /*       /\******\/ */
1.218     brouard  8050:       
1.227     brouard  8051: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8052: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8053: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8054: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8055: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8056:          
1.227     brouard  8057: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8058: /*       oldm=oldms;savm=savms; */
                   8059: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8060: /*       for (h=0; h<=nhstepm; h++){ */
                   8061: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8062: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8063: /*         }  */
                   8064: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8065: /*           kk1=0.;kk2=0; */
                   8066: /*           for(i=1; i<=nlstate;i++) {               */
                   8067: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8068: /*           } */
                   8069: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8070: /*         } */
                   8071: /*       } */
                   8072: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8073: /*     } */
                   8074: /*       } */
                   8075: /*     }  */
                   8076: /*   } */
1.218     brouard  8077:   
1.227     brouard  8078: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8079:   
1.227     brouard  8080: /*   if (popforecast==1) { */
                   8081: /*     free_ivector(popage,0,AGESUP); */
                   8082: /*     free_vector(popeffectif,0,AGESUP); */
                   8083: /*     free_vector(popcount,0,AGESUP); */
                   8084: /*   } */
                   8085: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8086: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8087: /*   fclose(ficrespop); */
                   8088: /* } /\* End of popforecast *\/ */
1.218     brouard  8089:  
1.126     brouard  8090: int fileappend(FILE *fichier, char *optionfich)
                   8091: {
                   8092:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8093:     printf("Problem with file: %s\n", optionfich);
                   8094:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8095:     return (0);
                   8096:   }
                   8097:   fflush(fichier);
                   8098:   return (1);
                   8099: }
                   8100: 
                   8101: 
                   8102: /**************** function prwizard **********************/
                   8103: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8104: {
                   8105: 
                   8106:   /* Wizard to print covariance matrix template */
                   8107: 
1.164     brouard  8108:   char ca[32], cb[32];
                   8109:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8110:   int numlinepar;
                   8111: 
                   8112:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8113:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8114:   for(i=1; i <=nlstate; i++){
                   8115:     jj=0;
                   8116:     for(j=1; j <=nlstate+ndeath; j++){
                   8117:       if(j==i) continue;
                   8118:       jj++;
                   8119:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8120:       printf("%1d%1d",i,j);
                   8121:       fprintf(ficparo,"%1d%1d",i,j);
                   8122:       for(k=1; k<=ncovmodel;k++){
                   8123:        /*        printf(" %lf",param[i][j][k]); */
                   8124:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8125:        printf(" 0.");
                   8126:        fprintf(ficparo," 0.");
                   8127:       }
                   8128:       printf("\n");
                   8129:       fprintf(ficparo,"\n");
                   8130:     }
                   8131:   }
                   8132:   printf("# Scales (for hessian or gradient estimation)\n");
                   8133:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8134:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8135:   for(i=1; i <=nlstate; i++){
                   8136:     jj=0;
                   8137:     for(j=1; j <=nlstate+ndeath; j++){
                   8138:       if(j==i) continue;
                   8139:       jj++;
                   8140:       fprintf(ficparo,"%1d%1d",i,j);
                   8141:       printf("%1d%1d",i,j);
                   8142:       fflush(stdout);
                   8143:       for(k=1; k<=ncovmodel;k++){
                   8144:        /*      printf(" %le",delti3[i][j][k]); */
                   8145:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8146:        printf(" 0.");
                   8147:        fprintf(ficparo," 0.");
                   8148:       }
                   8149:       numlinepar++;
                   8150:       printf("\n");
                   8151:       fprintf(ficparo,"\n");
                   8152:     }
                   8153:   }
                   8154:   printf("# Covariance matrix\n");
                   8155: /* # 121 Var(a12)\n\ */
                   8156: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8157: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8158: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8159: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8160: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8161: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8162: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8163:   fflush(stdout);
                   8164:   fprintf(ficparo,"# Covariance matrix\n");
                   8165:   /* # 121 Var(a12)\n\ */
                   8166:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8167:   /* #   ...\n\ */
                   8168:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8169:   
                   8170:   for(itimes=1;itimes<=2;itimes++){
                   8171:     jj=0;
                   8172:     for(i=1; i <=nlstate; i++){
                   8173:       for(j=1; j <=nlstate+ndeath; j++){
                   8174:        if(j==i) continue;
                   8175:        for(k=1; k<=ncovmodel;k++){
                   8176:          jj++;
                   8177:          ca[0]= k+'a'-1;ca[1]='\0';
                   8178:          if(itimes==1){
                   8179:            printf("#%1d%1d%d",i,j,k);
                   8180:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8181:          }else{
                   8182:            printf("%1d%1d%d",i,j,k);
                   8183:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8184:            /*  printf(" %.5le",matcov[i][j]); */
                   8185:          }
                   8186:          ll=0;
                   8187:          for(li=1;li <=nlstate; li++){
                   8188:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8189:              if(lj==li) continue;
                   8190:              for(lk=1;lk<=ncovmodel;lk++){
                   8191:                ll++;
                   8192:                if(ll<=jj){
                   8193:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8194:                  if(ll<jj){
                   8195:                    if(itimes==1){
                   8196:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8197:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8198:                    }else{
                   8199:                      printf(" 0.");
                   8200:                      fprintf(ficparo," 0.");
                   8201:                    }
                   8202:                  }else{
                   8203:                    if(itimes==1){
                   8204:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8205:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8206:                    }else{
                   8207:                      printf(" 0.");
                   8208:                      fprintf(ficparo," 0.");
                   8209:                    }
                   8210:                  }
                   8211:                }
                   8212:              } /* end lk */
                   8213:            } /* end lj */
                   8214:          } /* end li */
                   8215:          printf("\n");
                   8216:          fprintf(ficparo,"\n");
                   8217:          numlinepar++;
                   8218:        } /* end k*/
                   8219:       } /*end j */
                   8220:     } /* end i */
                   8221:   } /* end itimes */
                   8222: 
                   8223: } /* end of prwizard */
                   8224: /******************* Gompertz Likelihood ******************************/
                   8225: double gompertz(double x[])
                   8226: { 
                   8227:   double A,B,L=0.0,sump=0.,num=0.;
                   8228:   int i,n=0; /* n is the size of the sample */
                   8229: 
1.220     brouard  8230:   for (i=1;i<=imx ; i++) {
1.126     brouard  8231:     sump=sump+weight[i];
                   8232:     /*    sump=sump+1;*/
                   8233:     num=num+1;
                   8234:   }
                   8235:  
                   8236:  
                   8237:   /* for (i=0; i<=imx; i++) 
                   8238:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8239: 
                   8240:   for (i=1;i<=imx ; i++)
                   8241:     {
                   8242:       if (cens[i] == 1 && wav[i]>1)
                   8243:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8244:       
                   8245:       if (cens[i] == 0 && wav[i]>1)
                   8246:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8247:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8248:       
                   8249:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8250:       if (wav[i] > 1 ) { /* ??? */
                   8251:        L=L+A*weight[i];
                   8252:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8253:       }
                   8254:     }
                   8255: 
                   8256:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8257:  
                   8258:   return -2*L*num/sump;
                   8259: }
                   8260: 
1.136     brouard  8261: #ifdef GSL
                   8262: /******************* Gompertz_f Likelihood ******************************/
                   8263: double gompertz_f(const gsl_vector *v, void *params)
                   8264: { 
                   8265:   double A,B,LL=0.0,sump=0.,num=0.;
                   8266:   double *x= (double *) v->data;
                   8267:   int i,n=0; /* n is the size of the sample */
                   8268: 
                   8269:   for (i=0;i<=imx-1 ; i++) {
                   8270:     sump=sump+weight[i];
                   8271:     /*    sump=sump+1;*/
                   8272:     num=num+1;
                   8273:   }
                   8274:  
                   8275:  
                   8276:   /* for (i=0; i<=imx; i++) 
                   8277:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8278:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8279:   for (i=1;i<=imx ; i++)
                   8280:     {
                   8281:       if (cens[i] == 1 && wav[i]>1)
                   8282:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8283:       
                   8284:       if (cens[i] == 0 && wav[i]>1)
                   8285:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8286:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8287:       
                   8288:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8289:       if (wav[i] > 1 ) { /* ??? */
                   8290:        LL=LL+A*weight[i];
                   8291:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8292:       }
                   8293:     }
                   8294: 
                   8295:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8296:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8297:  
                   8298:   return -2*LL*num/sump;
                   8299: }
                   8300: #endif
                   8301: 
1.126     brouard  8302: /******************* Printing html file ***********/
1.201     brouard  8303: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8304:                  int lastpass, int stepm, int weightopt, char model[],\
                   8305:                  int imx,  double p[],double **matcov,double agemortsup){
                   8306:   int i,k;
                   8307: 
                   8308:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8309:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8310:   for (i=1;i<=2;i++) 
                   8311:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8312:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8313:   fprintf(fichtm,"</ul>");
                   8314: 
                   8315: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8316: 
                   8317:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8318: 
                   8319:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8320:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8321: 
                   8322:  
                   8323:   fflush(fichtm);
                   8324: }
                   8325: 
                   8326: /******************* Gnuplot file **************/
1.201     brouard  8327: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8328: 
                   8329:   char dirfileres[132],optfileres[132];
1.164     brouard  8330: 
1.126     brouard  8331:   int ng;
                   8332: 
                   8333: 
                   8334:   /*#ifdef windows */
                   8335:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8336:     /*#endif */
                   8337: 
                   8338: 
                   8339:   strcpy(dirfileres,optionfilefiname);
                   8340:   strcpy(optfileres,"vpl");
1.199     brouard  8341:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8342:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8343:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8344:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8345:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8346: 
                   8347: } 
                   8348: 
1.136     brouard  8349: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8350: {
1.126     brouard  8351: 
1.136     brouard  8352:   /*-------- data file ----------*/
                   8353:   FILE *fic;
                   8354:   char dummy[]="                         ";
1.240     brouard  8355:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8356:   int lstra;
1.136     brouard  8357:   int linei, month, year,iout;
                   8358:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8359:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8360:   char *stratrunc;
1.223     brouard  8361: 
1.240     brouard  8362:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8363:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8364: 
1.240     brouard  8365:   for(v=1; v <=ncovcol;v++){
                   8366:     DummyV[v]=0;
                   8367:     FixedV[v]=0;
                   8368:   }
                   8369:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8370:     DummyV[v]=1;
                   8371:     FixedV[v]=0;
                   8372:   }
                   8373:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8374:     DummyV[v]=0;
                   8375:     FixedV[v]=1;
                   8376:   }
                   8377:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8378:     DummyV[v]=1;
                   8379:     FixedV[v]=1;
                   8380:   }
                   8381:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8382:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8383:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8384:   }
1.126     brouard  8385: 
1.136     brouard  8386:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8387:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8388:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8389:   }
1.126     brouard  8390: 
1.136     brouard  8391:   i=1;
                   8392:   linei=0;
                   8393:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8394:     linei=linei+1;
                   8395:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8396:       if(line[j] == '\t')
                   8397:        line[j] = ' ';
                   8398:     }
                   8399:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8400:       ;
                   8401:     };
                   8402:     line[j+1]=0;  /* Trims blanks at end of line */
                   8403:     if(line[0]=='#'){
                   8404:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8405:       printf("Comment line\n%s\n",line);
                   8406:       continue;
                   8407:     }
                   8408:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8409:     strcpy(line, linetmp);
1.223     brouard  8410:     
                   8411:     /* Loops on waves */
                   8412:     for (j=maxwav;j>=1;j--){
                   8413:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8414:        cutv(stra, strb, line, ' '); 
                   8415:        if(strb[0]=='.') { /* Missing value */
                   8416:          lval=-1;
                   8417:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8418:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8419:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8420:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8421:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8422:            return 1;
                   8423:          }
                   8424:        }else{
                   8425:          errno=0;
                   8426:          /* what_kind_of_number(strb); */
                   8427:          dval=strtod(strb,&endptr); 
                   8428:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8429:          /* if(strb != endptr && *endptr == '\0') */
                   8430:          /*    dval=dlval; */
                   8431:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8432:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8433:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8434:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8435:            return 1;
                   8436:          }
                   8437:          cotqvar[j][iv][i]=dval; 
                   8438:          cotvar[j][ntv+iv][i]=dval; 
                   8439:        }
                   8440:        strcpy(line,stra);
1.223     brouard  8441:       }/* end loop ntqv */
1.225     brouard  8442:       
1.223     brouard  8443:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8444:        cutv(stra, strb, line, ' '); 
                   8445:        if(strb[0]=='.') { /* Missing value */
                   8446:          lval=-1;
                   8447:        }else{
                   8448:          errno=0;
                   8449:          lval=strtol(strb,&endptr,10); 
                   8450:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8451:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8452:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8453:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8454:            return 1;
                   8455:          }
                   8456:        }
                   8457:        if(lval <-1 || lval >1){
                   8458:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8459:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8460:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8461:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8462:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8463:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8464:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8465:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8466:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8467:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8468:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8469:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8470:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8471:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8472:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8473:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8474:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8475:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8476:          return 1;
                   8477:        }
                   8478:        cotvar[j][iv][i]=(double)(lval);
                   8479:        strcpy(line,stra);
1.223     brouard  8480:       }/* end loop ntv */
1.225     brouard  8481:       
1.223     brouard  8482:       /* Statuses  at wave */
1.137     brouard  8483:       cutv(stra, strb, line, ' '); 
1.223     brouard  8484:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8485:        lval=-1;
1.136     brouard  8486:       }else{
1.238     brouard  8487:        errno=0;
                   8488:        lval=strtol(strb,&endptr,10); 
                   8489:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8490:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8491:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8492:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8493:          return 1;
                   8494:        }
1.136     brouard  8495:       }
1.225     brouard  8496:       
1.136     brouard  8497:       s[j][i]=lval;
1.225     brouard  8498:       
1.223     brouard  8499:       /* Date of Interview */
1.136     brouard  8500:       strcpy(line,stra);
                   8501:       cutv(stra, strb,line,' ');
1.169     brouard  8502:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8503:       }
1.169     brouard  8504:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8505:        month=99;
                   8506:        year=9999;
1.136     brouard  8507:       }else{
1.225     brouard  8508:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8509:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8510:        return 1;
1.136     brouard  8511:       }
                   8512:       anint[j][i]= (double) year; 
                   8513:       mint[j][i]= (double)month; 
                   8514:       strcpy(line,stra);
1.223     brouard  8515:     } /* End loop on waves */
1.225     brouard  8516:     
1.223     brouard  8517:     /* Date of death */
1.136     brouard  8518:     cutv(stra, strb,line,' '); 
1.169     brouard  8519:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8520:     }
1.169     brouard  8521:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8522:       month=99;
                   8523:       year=9999;
                   8524:     }else{
1.141     brouard  8525:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8526:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8527:       return 1;
1.136     brouard  8528:     }
                   8529:     andc[i]=(double) year; 
                   8530:     moisdc[i]=(double) month; 
                   8531:     strcpy(line,stra);
                   8532:     
1.223     brouard  8533:     /* Date of birth */
1.136     brouard  8534:     cutv(stra, strb,line,' '); 
1.169     brouard  8535:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8536:     }
1.169     brouard  8537:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8538:       month=99;
                   8539:       year=9999;
                   8540:     }else{
1.141     brouard  8541:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8542:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8543:       return 1;
1.136     brouard  8544:     }
                   8545:     if (year==9999) {
1.141     brouard  8546:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8547:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8548:       return 1;
                   8549:       
1.136     brouard  8550:     }
                   8551:     annais[i]=(double)(year);
                   8552:     moisnais[i]=(double)(month); 
                   8553:     strcpy(line,stra);
1.225     brouard  8554:     
1.223     brouard  8555:     /* Sample weight */
1.136     brouard  8556:     cutv(stra, strb,line,' '); 
                   8557:     errno=0;
                   8558:     dval=strtod(strb,&endptr); 
                   8559:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8560:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8561:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8562:       fflush(ficlog);
                   8563:       return 1;
                   8564:     }
                   8565:     weight[i]=dval; 
                   8566:     strcpy(line,stra);
1.225     brouard  8567:     
1.223     brouard  8568:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8569:       cutv(stra, strb, line, ' '); 
                   8570:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8571:        lval=-1;
1.223     brouard  8572:       }else{
1.225     brouard  8573:        errno=0;
                   8574:        /* what_kind_of_number(strb); */
                   8575:        dval=strtod(strb,&endptr);
                   8576:        /* if(strb != endptr && *endptr == '\0') */
                   8577:        /*   dval=dlval; */
                   8578:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8579:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8580:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8581:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8582:          return 1;
                   8583:        }
                   8584:        coqvar[iv][i]=dval; 
1.226     brouard  8585:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8586:       }
                   8587:       strcpy(line,stra);
                   8588:     }/* end loop nqv */
1.136     brouard  8589:     
1.223     brouard  8590:     /* Covariate values */
1.136     brouard  8591:     for (j=ncovcol;j>=1;j--){
                   8592:       cutv(stra, strb,line,' '); 
1.223     brouard  8593:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8594:        lval=-1;
1.136     brouard  8595:       }else{
1.225     brouard  8596:        errno=0;
                   8597:        lval=strtol(strb,&endptr,10); 
                   8598:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8599:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8600:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8601:          return 1;
                   8602:        }
1.136     brouard  8603:       }
                   8604:       if(lval <-1 || lval >1){
1.225     brouard  8605:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8606:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8607:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8608:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8609:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8610:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8611:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8612:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8613:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8614:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8615:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8616:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8617:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8618:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8619:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8620:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8621:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8622:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8623:        return 1;
1.136     brouard  8624:       }
                   8625:       covar[j][i]=(double)(lval);
                   8626:       strcpy(line,stra);
                   8627:     }  
                   8628:     lstra=strlen(stra);
1.225     brouard  8629:     
1.136     brouard  8630:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8631:       stratrunc = &(stra[lstra-9]);
                   8632:       num[i]=atol(stratrunc);
                   8633:     }
                   8634:     else
                   8635:       num[i]=atol(stra);
                   8636:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8637:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8638:     
                   8639:     i=i+1;
                   8640:   } /* End loop reading  data */
1.225     brouard  8641:   
1.136     brouard  8642:   *imax=i-1; /* Number of individuals */
                   8643:   fclose(fic);
1.225     brouard  8644:   
1.136     brouard  8645:   return (0);
1.164     brouard  8646:   /* endread: */
1.225     brouard  8647:   printf("Exiting readdata: ");
                   8648:   fclose(fic);
                   8649:   return (1);
1.223     brouard  8650: }
1.126     brouard  8651: 
1.234     brouard  8652: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8653:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8654:   while (*p2 == ' ')
1.234     brouard  8655:     p2++; 
                   8656:   /* while ((*p1++ = *p2++) !=0) */
                   8657:   /*   ; */
                   8658:   /* do */
                   8659:   /*   while (*p2 == ' ') */
                   8660:   /*     p2++; */
                   8661:   /* while (*p1++ == *p2++); */
                   8662:   *stri=p2; 
1.145     brouard  8663: }
                   8664: 
1.235     brouard  8665: int decoderesult ( char resultline[], int nres)
1.230     brouard  8666: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8667: {
1.235     brouard  8668:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8669:   char resultsav[MAXLINE];
1.234     brouard  8670:   int resultmodel[MAXLINE];
                   8671:   int modelresult[MAXLINE];
1.230     brouard  8672:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8673: 
1.234     brouard  8674:   removefirstspace(&resultline);
1.233     brouard  8675:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8676: 
                   8677:   if (strstr(resultline,"v") !=0){
                   8678:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8679:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8680:     return 1;
                   8681:   }
                   8682:   trimbb(resultsav, resultline);
                   8683:   if (strlen(resultsav) >1){
                   8684:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8685:   }
1.253     brouard  8686:   if(j == 0){ /* Resultline but no = */
                   8687:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8688:     return (0);
                   8689:   }
                   8690:     
1.234     brouard  8691:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8692:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8693:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8694:   }
                   8695:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8696:     if(nbocc(resultsav,'=') >1){
                   8697:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8698:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8699:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8700:     }else
                   8701:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8702:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8703:     
1.230     brouard  8704:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8705:     Tvarsel[k]=atoi(strc);
                   8706:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8707:     /* cptcovsel++;     */
                   8708:     if (nbocc(stra,'=') >0)
                   8709:       strcpy(resultsav,stra); /* and analyzes it */
                   8710:   }
1.235     brouard  8711:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8712:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8713:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8714:       match=0;
1.236     brouard  8715:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8716:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8717:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8718:          match=1;
                   8719:          break;
                   8720:        }
                   8721:       }
                   8722:       if(match == 0){
                   8723:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8724:       }
                   8725:     }
                   8726:   }
1.235     brouard  8727:   /* Checking for missing or useless values in comparison of current model needs */
                   8728:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8729:     match=0;
1.235     brouard  8730:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8731:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8732:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8733:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8734:          ++match;
                   8735:        }
                   8736:       }
                   8737:     }
                   8738:     if(match == 0){
                   8739:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8740:     }else if(match > 1){
                   8741:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8742:     }
                   8743:   }
1.235     brouard  8744:       
1.234     brouard  8745:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8746:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8747:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8748:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8749:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8750:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8751:   /*    1 0 0 0 */
                   8752:   /*    2 1 0 0 */
                   8753:   /*    3 0 1 0 */ 
                   8754:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8755:   /*    5 0 0 1 */
                   8756:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8757:   /*    7 0 1 1 */
                   8758:   /*    8 1 1 1 */
1.237     brouard  8759:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8760:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8761:   /* V5*age V5 known which value for nres?  */
                   8762:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8763:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8764:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8765:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8766:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8767:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8768:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8769:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8770:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8771:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8772:       k4++;;
                   8773:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8774:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8775:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8776:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8777:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8778:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8779:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8780:       k4q++;;
                   8781:     }
                   8782:   }
1.234     brouard  8783:   
1.235     brouard  8784:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8785:   return (0);
                   8786: }
1.235     brouard  8787: 
1.230     brouard  8788: int decodemodel( char model[], int lastobs)
                   8789:  /**< This routine decodes the model and returns:
1.224     brouard  8790:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8791:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8792:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8793:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8794:        * - cptcovage number of covariates with age*products =2
                   8795:        * - cptcovs number of simple covariates
                   8796:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8797:        *     which is a new column after the 9 (ncovcol) variables. 
                   8798:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8799:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8800:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8801:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8802:        */
1.136     brouard  8803: {
1.238     brouard  8804:   int i, j, k, ks, v;
1.227     brouard  8805:   int  j1, k1, k2, k3, k4;
1.136     brouard  8806:   char modelsav[80];
1.145     brouard  8807:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8808:   char *strpt;
1.136     brouard  8809: 
1.145     brouard  8810:   /*removespace(model);*/
1.136     brouard  8811:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8812:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8813:     if (strstr(model,"AGE") !=0){
1.192     brouard  8814:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8815:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8816:       return 1;
                   8817:     }
1.141     brouard  8818:     if (strstr(model,"v") !=0){
                   8819:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8820:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8821:       return 1;
                   8822:     }
1.187     brouard  8823:     strcpy(modelsav,model); 
                   8824:     if ((strpt=strstr(model,"age*age")) !=0){
                   8825:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8826:       if(strpt != model){
1.234     brouard  8827:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8828:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8829:  corresponding column of parameters.\n",model);
1.234     brouard  8830:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8831:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8832:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8833:        return 1;
1.225     brouard  8834:       }
1.187     brouard  8835:       nagesqr=1;
                   8836:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8837:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8838:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8839:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8840:       else 
1.234     brouard  8841:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8842:     }else
                   8843:       nagesqr=0;
                   8844:     if (strlen(modelsav) >1){
                   8845:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8846:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8847:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8848:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8849:                     * cst, age and age*age 
                   8850:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8851:       /* including age products which are counted in cptcovage.
                   8852:        * but the covariates which are products must be treated 
                   8853:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8854:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8855:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8856:       
                   8857:       
1.187     brouard  8858:       /*   Design
                   8859:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8860:        *  <          ncovcol=8                >
                   8861:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8862:        *   k=  1    2      3       4     5       6      7        8
                   8863:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8864:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8865:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8866:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8867:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8868:        *  Tage[++cptcovage]=k
                   8869:        *       if products, new covar are created after ncovcol with k1
                   8870:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8871:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8872:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8873:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8874:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8875:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8876:        *  <          ncovcol=8                >
                   8877:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8878:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8879:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8880:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8881:        * p Tprod[1]@2={                         6, 5}
                   8882:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8883:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8884:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8885:        *How to reorganize?
                   8886:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8887:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8888:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8889:        * Struct []
                   8890:        */
1.225     brouard  8891:       
1.187     brouard  8892:       /* This loop fills the array Tvar from the string 'model'.*/
                   8893:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8894:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8895:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8896:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8897:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8898:       /*       k=1 Tvar[1]=2 (from V2) */
                   8899:       /*       k=5 Tvar[5] */
                   8900:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8901:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8902:       /*       } */
1.198     brouard  8903:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8904:       /*
                   8905:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8906:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8907:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8908:       }
1.187     brouard  8909:       cptcovage=0;
                   8910:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8911:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8912:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8913:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8914:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8915:        /*scanf("%d",i);*/
                   8916:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8917:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8918:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8919:            /* covar is not filled and then is empty */
                   8920:            cptcovprod--;
                   8921:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8922:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8923:            Typevar[k]=1;  /* 1 for age product */
                   8924:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8925:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8926:            /*printf("stre=%s ", stre);*/
                   8927:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8928:            cptcovprod--;
                   8929:            cutl(stre,strb,strc,'V');
                   8930:            Tvar[k]=atoi(stre);
                   8931:            Typevar[k]=1;  /* 1 for age product */
                   8932:            cptcovage++;
                   8933:            Tage[cptcovage]=k;
                   8934:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8935:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8936:            cptcovn++;
                   8937:            cptcovprodnoage++;k1++;
                   8938:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8939:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8940:                                                because this model-covariate is a construction we invent a new column
                   8941:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8942:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8943:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8944:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8945:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8946:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8947:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8948:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8949:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8950:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8951:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8952:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8953:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8954:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8955:            for (i=1; i<=lastobs;i++){
                   8956:              /* Computes the new covariate which is a product of
                   8957:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8958:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8959:            }
                   8960:          } /* End age is not in the model */
                   8961:        } /* End if model includes a product */
                   8962:        else { /* no more sum */
                   8963:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8964:          /*  scanf("%d",i);*/
                   8965:          cutl(strd,strc,strb,'V');
                   8966:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8967:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8968:          Tvar[k]=atoi(strd);
                   8969:          Typevar[k]=0;  /* 0 for simple covariates */
                   8970:        }
                   8971:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8972:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8973:                                  scanf("%d",i);*/
1.187     brouard  8974:       } /* end of loop + on total covariates */
                   8975:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8976:   } /* end if strlen(model == 0) */
1.136     brouard  8977:   
                   8978:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8979:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8980:   
1.136     brouard  8981:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8982:      printf("cptcovprod=%d ", cptcovprod);
                   8983:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8984:      scanf("%d ",i);*/
                   8985: 
                   8986: 
1.230     brouard  8987: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8988:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8989: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8990:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8991:    k =           1    2   3     4       5       6      7      8        9
                   8992:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8993:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8994:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8995:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8996:          Tmodelind[combination of covar]=k;
1.225     brouard  8997: */  
                   8998: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8999:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9000:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9001:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9002:   printf("Model=%s\n\
                   9003: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9004: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9005: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9006:   fprintf(ficlog,"Model=%s\n\
                   9007: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9008: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9009: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9010:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9011:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9012:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9013:       Fixed[k]= 0;
                   9014:       Dummy[k]= 0;
1.225     brouard  9015:       ncoveff++;
1.232     brouard  9016:       ncovf++;
1.234     brouard  9017:       nsd++;
                   9018:       modell[k].maintype= FTYPE;
                   9019:       TvarsD[nsd]=Tvar[k];
                   9020:       TvarsDind[nsd]=k;
                   9021:       TvarF[ncovf]=Tvar[k];
                   9022:       TvarFind[ncovf]=k;
                   9023:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9024:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9025:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9026:       Fixed[k]= 0;
                   9027:       Dummy[k]= 0;
                   9028:       ncoveff++;
                   9029:       ncovf++;
                   9030:       modell[k].maintype= FTYPE;
                   9031:       TvarF[ncovf]=Tvar[k];
                   9032:       TvarFind[ncovf]=k;
1.230     brouard  9033:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9034:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9035:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9036:       Fixed[k]= 0;
                   9037:       Dummy[k]= 1;
1.230     brouard  9038:       nqfveff++;
1.234     brouard  9039:       modell[k].maintype= FTYPE;
                   9040:       modell[k].subtype= FQ;
                   9041:       nsq++;
                   9042:       TvarsQ[nsq]=Tvar[k];
                   9043:       TvarsQind[nsq]=k;
1.232     brouard  9044:       ncovf++;
1.234     brouard  9045:       TvarF[ncovf]=Tvar[k];
                   9046:       TvarFind[ncovf]=k;
1.231     brouard  9047:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9048:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9049:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9050:       Fixed[k]= 1;
                   9051:       Dummy[k]= 0;
1.225     brouard  9052:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9053:       modell[k].maintype= VTYPE;
                   9054:       modell[k].subtype= VD;
                   9055:       nsd++;
                   9056:       TvarsD[nsd]=Tvar[k];
                   9057:       TvarsDind[nsd]=k;
                   9058:       ncovv++; /* Only simple time varying variables */
                   9059:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9060:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9061:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9062:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9063:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9064:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9065:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9066:       Fixed[k]= 1;
                   9067:       Dummy[k]= 1;
                   9068:       nqtveff++;
                   9069:       modell[k].maintype= VTYPE;
                   9070:       modell[k].subtype= VQ;
                   9071:       ncovv++; /* Only simple time varying variables */
                   9072:       nsq++;
                   9073:       TvarsQ[nsq]=Tvar[k];
                   9074:       TvarsQind[nsq]=k;
                   9075:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9076:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9077:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9078:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9079:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9080:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9081:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9082:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9083:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9084:       ncova++;
                   9085:       TvarA[ncova]=Tvar[k];
                   9086:       TvarAind[ncova]=k;
1.231     brouard  9087:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9088:        Fixed[k]= 2;
                   9089:        Dummy[k]= 2;
                   9090:        modell[k].maintype= ATYPE;
                   9091:        modell[k].subtype= APFD;
                   9092:        /* ncoveff++; */
1.227     brouard  9093:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9094:        Fixed[k]= 2;
                   9095:        Dummy[k]= 3;
                   9096:        modell[k].maintype= ATYPE;
                   9097:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9098:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9099:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9100:        Fixed[k]= 3;
                   9101:        Dummy[k]= 2;
                   9102:        modell[k].maintype= ATYPE;
                   9103:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9104:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9105:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9106:        Fixed[k]= 3;
                   9107:        Dummy[k]= 3;
                   9108:        modell[k].maintype= ATYPE;
                   9109:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9110:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9111:       }
                   9112:     }else if (Typevar[k] == 2) {  /* product without age */
                   9113:       k1=Tposprod[k];
                   9114:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9115:        if(Tvard[k1][2] <=ncovcol){
                   9116:          Fixed[k]= 1;
                   9117:          Dummy[k]= 0;
                   9118:          modell[k].maintype= FTYPE;
                   9119:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9120:          ncovf++; /* Fixed variables without age */
                   9121:          TvarF[ncovf]=Tvar[k];
                   9122:          TvarFind[ncovf]=k;
                   9123:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9124:          Fixed[k]= 0;  /* or 2 ?*/
                   9125:          Dummy[k]= 1;
                   9126:          modell[k].maintype= FTYPE;
                   9127:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9128:          ncovf++; /* Varying variables without age */
                   9129:          TvarF[ncovf]=Tvar[k];
                   9130:          TvarFind[ncovf]=k;
                   9131:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9132:          Fixed[k]= 1;
                   9133:          Dummy[k]= 0;
                   9134:          modell[k].maintype= VTYPE;
                   9135:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9136:          ncovv++; /* Varying variables without age */
                   9137:          TvarV[ncovv]=Tvar[k];
                   9138:          TvarVind[ncovv]=k;
                   9139:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9140:          Fixed[k]= 1;
                   9141:          Dummy[k]= 1;
                   9142:          modell[k].maintype= VTYPE;
                   9143:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9144:          ncovv++; /* Varying variables without age */
                   9145:          TvarV[ncovv]=Tvar[k];
                   9146:          TvarVind[ncovv]=k;
                   9147:        }
1.227     brouard  9148:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9149:        if(Tvard[k1][2] <=ncovcol){
                   9150:          Fixed[k]= 0;  /* or 2 ?*/
                   9151:          Dummy[k]= 1;
                   9152:          modell[k].maintype= FTYPE;
                   9153:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9154:          ncovf++; /* Fixed variables without age */
                   9155:          TvarF[ncovf]=Tvar[k];
                   9156:          TvarFind[ncovf]=k;
                   9157:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9158:          Fixed[k]= 1;
                   9159:          Dummy[k]= 1;
                   9160:          modell[k].maintype= VTYPE;
                   9161:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9162:          ncovv++; /* Varying variables without age */
                   9163:          TvarV[ncovv]=Tvar[k];
                   9164:          TvarVind[ncovv]=k;
                   9165:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9166:          Fixed[k]= 1;
                   9167:          Dummy[k]= 1;
                   9168:          modell[k].maintype= VTYPE;
                   9169:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9170:          ncovv++; /* Varying variables without age */
                   9171:          TvarV[ncovv]=Tvar[k];
                   9172:          TvarVind[ncovv]=k;
                   9173:          ncovv++; /* Varying variables without age */
                   9174:          TvarV[ncovv]=Tvar[k];
                   9175:          TvarVind[ncovv]=k;
                   9176:        }
1.227     brouard  9177:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9178:        if(Tvard[k1][2] <=ncovcol){
                   9179:          Fixed[k]= 1;
                   9180:          Dummy[k]= 1;
                   9181:          modell[k].maintype= VTYPE;
                   9182:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9183:          ncovv++; /* Varying variables without age */
                   9184:          TvarV[ncovv]=Tvar[k];
                   9185:          TvarVind[ncovv]=k;
                   9186:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9187:          Fixed[k]= 1;
                   9188:          Dummy[k]= 1;
                   9189:          modell[k].maintype= VTYPE;
                   9190:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9191:          ncovv++; /* Varying variables without age */
                   9192:          TvarV[ncovv]=Tvar[k];
                   9193:          TvarVind[ncovv]=k;
                   9194:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9195:          Fixed[k]= 1;
                   9196:          Dummy[k]= 0;
                   9197:          modell[k].maintype= VTYPE;
                   9198:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9199:          ncovv++; /* Varying variables without age */
                   9200:          TvarV[ncovv]=Tvar[k];
                   9201:          TvarVind[ncovv]=k;
                   9202:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9203:          Fixed[k]= 1;
                   9204:          Dummy[k]= 1;
                   9205:          modell[k].maintype= VTYPE;
                   9206:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9207:          ncovv++; /* Varying variables without age */
                   9208:          TvarV[ncovv]=Tvar[k];
                   9209:          TvarVind[ncovv]=k;
                   9210:        }
1.227     brouard  9211:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9212:        if(Tvard[k1][2] <=ncovcol){
                   9213:          Fixed[k]= 1;
                   9214:          Dummy[k]= 1;
                   9215:          modell[k].maintype= VTYPE;
                   9216:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9217:          ncovv++; /* Varying variables without age */
                   9218:          TvarV[ncovv]=Tvar[k];
                   9219:          TvarVind[ncovv]=k;
                   9220:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9221:          Fixed[k]= 1;
                   9222:          Dummy[k]= 1;
                   9223:          modell[k].maintype= VTYPE;
                   9224:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9225:          ncovv++; /* Varying variables without age */
                   9226:          TvarV[ncovv]=Tvar[k];
                   9227:          TvarVind[ncovv]=k;
                   9228:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9229:          Fixed[k]= 1;
                   9230:          Dummy[k]= 1;
                   9231:          modell[k].maintype= VTYPE;
                   9232:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9233:          ncovv++; /* Varying variables without age */
                   9234:          TvarV[ncovv]=Tvar[k];
                   9235:          TvarVind[ncovv]=k;
                   9236:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9237:          Fixed[k]= 1;
                   9238:          Dummy[k]= 1;
                   9239:          modell[k].maintype= VTYPE;
                   9240:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9241:          ncovv++; /* Varying variables without age */
                   9242:          TvarV[ncovv]=Tvar[k];
                   9243:          TvarVind[ncovv]=k;
                   9244:        }
1.227     brouard  9245:       }else{
1.240     brouard  9246:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9247:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9248:       } /*end k1*/
1.225     brouard  9249:     }else{
1.226     brouard  9250:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9251:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9252:     }
1.227     brouard  9253:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9254:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9255:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9256:   }
                   9257:   /* Searching for doublons in the model */
                   9258:   for(k1=1; k1<= cptcovt;k1++){
                   9259:     for(k2=1; k2 <k1;k2++){
                   9260:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9261:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9262:          if(Tvar[k1]==Tvar[k2]){
                   9263:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9264:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9265:            return(1);
                   9266:          }
                   9267:        }else if (Typevar[k1] ==2){
                   9268:          k3=Tposprod[k1];
                   9269:          k4=Tposprod[k2];
                   9270:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9271:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9272:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9273:            return(1);
                   9274:          }
                   9275:        }
1.227     brouard  9276:       }
                   9277:     }
1.225     brouard  9278:   }
                   9279:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9280:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9281:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9282:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9283:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9284:   /*endread:*/
1.225     brouard  9285:   printf("Exiting decodemodel: ");
                   9286:   return (1);
1.136     brouard  9287: }
                   9288: 
1.169     brouard  9289: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9290: {/* Check ages at death */
1.136     brouard  9291:   int i, m;
1.218     brouard  9292:   int firstone=0;
                   9293:   
1.136     brouard  9294:   for (i=1; i<=imx; i++) {
                   9295:     for(m=2; (m<= maxwav); m++) {
                   9296:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9297:        anint[m][i]=9999;
1.216     brouard  9298:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9299:          s[m][i]=-1;
1.136     brouard  9300:       }
                   9301:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9302:        *nberr = *nberr + 1;
1.218     brouard  9303:        if(firstone == 0){
                   9304:          firstone=1;
1.260     brouard  9305:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9306:        }
1.262     brouard  9307:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9308:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9309:       }
                   9310:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9311:        (*nberr)++;
1.259     brouard  9312:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9313:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9314:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9315:       }
                   9316:     }
                   9317:   }
                   9318: 
                   9319:   for (i=1; i<=imx; i++)  {
                   9320:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9321:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9322:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9323:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9324:          if(agedc[i]>0){
                   9325:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9326:              agev[m][i]=agedc[i];
1.214     brouard  9327:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9328:            }else {
1.136     brouard  9329:              if ((int)andc[i]!=9999){
                   9330:                nbwarn++;
                   9331:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9332:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9333:                agev[m][i]=-1;
                   9334:              }
                   9335:            }
1.169     brouard  9336:          } /* agedc > 0 */
1.214     brouard  9337:        } /* end if */
1.136     brouard  9338:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9339:                                 years but with the precision of a month */
                   9340:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9341:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9342:            agev[m][i]=1;
                   9343:          else if(agev[m][i] < *agemin){ 
                   9344:            *agemin=agev[m][i];
                   9345:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9346:          }
                   9347:          else if(agev[m][i] >*agemax){
                   9348:            *agemax=agev[m][i];
1.156     brouard  9349:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9350:          }
                   9351:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9352:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9353:        } /* en if 9*/
1.136     brouard  9354:        else { /* =9 */
1.214     brouard  9355:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9356:          agev[m][i]=1;
                   9357:          s[m][i]=-1;
                   9358:        }
                   9359:       }
1.214     brouard  9360:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9361:        agev[m][i]=1;
1.214     brouard  9362:       else{
                   9363:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9364:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9365:        agev[m][i]=0;
                   9366:       }
                   9367:     } /* End for lastpass */
                   9368:   }
1.136     brouard  9369:     
                   9370:   for (i=1; i<=imx; i++)  {
                   9371:     for(m=firstpass; (m<=lastpass); m++){
                   9372:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9373:        (*nberr)++;
1.136     brouard  9374:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9375:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9376:        return 1;
                   9377:       }
                   9378:     }
                   9379:   }
                   9380: 
                   9381:   /*for (i=1; i<=imx; i++){
                   9382:   for (m=firstpass; (m<lastpass); m++){
                   9383:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9384: }
                   9385: 
                   9386: }*/
                   9387: 
                   9388: 
1.139     brouard  9389:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9390:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9391: 
                   9392:   return (0);
1.164     brouard  9393:  /* endread:*/
1.136     brouard  9394:     printf("Exiting calandcheckages: ");
                   9395:     return (1);
                   9396: }
                   9397: 
1.172     brouard  9398: #if defined(_MSC_VER)
                   9399: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9400: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9401: //#include "stdafx.h"
                   9402: //#include <stdio.h>
                   9403: //#include <tchar.h>
                   9404: //#include <windows.h>
                   9405: //#include <iostream>
                   9406: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9407: 
                   9408: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9409: 
                   9410: BOOL IsWow64()
                   9411: {
                   9412:        BOOL bIsWow64 = FALSE;
                   9413: 
                   9414:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9415:        //  (HANDLE, PBOOL);
                   9416: 
                   9417:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9418: 
                   9419:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9420:        const char funcName[] = "IsWow64Process";
                   9421:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9422:                GetProcAddress(module, funcName);
                   9423: 
                   9424:        if (NULL != fnIsWow64Process)
                   9425:        {
                   9426:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9427:                        &bIsWow64))
                   9428:                        //throw std::exception("Unknown error");
                   9429:                        printf("Unknown error\n");
                   9430:        }
                   9431:        return bIsWow64 != FALSE;
                   9432: }
                   9433: #endif
1.177     brouard  9434: 
1.191     brouard  9435: void syscompilerinfo(int logged)
1.167     brouard  9436:  {
                   9437:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9438:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9439:    /* /GS /W3 /Gy
                   9440:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9441:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9442:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9443:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9444:    */ 
                   9445:    /* 64 bits */
1.185     brouard  9446:    /*
                   9447:      /GS /W3 /Gy
                   9448:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9449:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9450:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9451:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9452:    /* Optimization are useless and O3 is slower than O2 */
                   9453:    /*
                   9454:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9455:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9456:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9457:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9458:    */
1.186     brouard  9459:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9460:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9461:       /PDB:"visual studio
                   9462:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9463:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9464:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9465:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9466:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9467:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9468:       uiAccess='false'"
                   9469:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9470:       /NOLOGO /TLBID:1
                   9471:    */
1.177     brouard  9472: #if defined __INTEL_COMPILER
1.178     brouard  9473: #if defined(__GNUC__)
                   9474:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9475: #endif
1.177     brouard  9476: #elif defined(__GNUC__) 
1.179     brouard  9477: #ifndef  __APPLE__
1.174     brouard  9478: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9479: #endif
1.177     brouard  9480:    struct utsname sysInfo;
1.178     brouard  9481:    int cross = CROSS;
                   9482:    if (cross){
                   9483:           printf("Cross-");
1.191     brouard  9484:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9485:    }
1.174     brouard  9486: #endif
                   9487: 
1.171     brouard  9488: #include <stdint.h>
1.178     brouard  9489: 
1.191     brouard  9490:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9491: #if defined(__clang__)
1.191     brouard  9492:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9493: #endif
                   9494: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9495:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9496: #endif
                   9497: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9498:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9499: #endif
                   9500: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9501:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9502: #endif
                   9503: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9504:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9505: #endif
                   9506: #if defined(_MSC_VER)
1.191     brouard  9507:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9508: #endif
                   9509: #if defined(__PGI)
1.191     brouard  9510:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9511: #endif
                   9512: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9513:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9514: #endif
1.191     brouard  9515:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9516:    
1.167     brouard  9517: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9518: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9519:     // Windows (x64 and x86)
1.191     brouard  9520:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9521: #elif __unix__ // all unices, not all compilers
                   9522:     // Unix
1.191     brouard  9523:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9524: #elif __linux__
                   9525:     // linux
1.191     brouard  9526:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9527: #elif __APPLE__
1.174     brouard  9528:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9529:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9530: #endif
                   9531: 
                   9532: /*  __MINGW32__          */
                   9533: /*  __CYGWIN__  */
                   9534: /* __MINGW64__  */
                   9535: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9536: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9537: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9538: /* _WIN64  // Defined for applications for Win64. */
                   9539: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9540: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9541: 
1.167     brouard  9542: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9543:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9544: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9545:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9546: #else
1.191     brouard  9547:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9548: #endif
                   9549: 
1.169     brouard  9550: #if defined(__GNUC__)
                   9551: # if defined(__GNUC_PATCHLEVEL__)
                   9552: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9553:                             + __GNUC_MINOR__ * 100 \
                   9554:                             + __GNUC_PATCHLEVEL__)
                   9555: # else
                   9556: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9557:                             + __GNUC_MINOR__ * 100)
                   9558: # endif
1.174     brouard  9559:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9560:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9561: 
                   9562:    if (uname(&sysInfo) != -1) {
                   9563:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9564:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9565:    }
                   9566:    else
                   9567:       perror("uname() error");
1.179     brouard  9568:    //#ifndef __INTEL_COMPILER 
                   9569: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9570:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9571:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9572: #endif
1.169     brouard  9573: #endif
1.172     brouard  9574: 
                   9575:    //   void main()
                   9576:    //   {
1.169     brouard  9577: #if defined(_MSC_VER)
1.174     brouard  9578:    if (IsWow64()){
1.191     brouard  9579:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9580:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9581:    }
                   9582:    else{
1.191     brouard  9583:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9584:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9585:    }
1.172     brouard  9586:    //     printf("\nPress Enter to continue...");
                   9587:    //     getchar();
                   9588:    //   }
                   9589: 
1.169     brouard  9590: #endif
                   9591:    
1.167     brouard  9592: 
1.219     brouard  9593: }
1.136     brouard  9594: 
1.219     brouard  9595: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9596:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9597:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9598:   /* double ftolpl = 1.e-10; */
1.180     brouard  9599:   double age, agebase, agelim;
1.203     brouard  9600:   double tot;
1.180     brouard  9601: 
1.202     brouard  9602:   strcpy(filerespl,"PL_");
                   9603:   strcat(filerespl,fileresu);
                   9604:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9605:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9606:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9607:   }
1.227     brouard  9608:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9609:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9610:   pstamp(ficrespl);
1.203     brouard  9611:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9612:   fprintf(ficrespl,"#Age ");
                   9613:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9614:   fprintf(ficrespl,"\n");
1.180     brouard  9615:   
1.219     brouard  9616:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9617: 
1.219     brouard  9618:   agebase=ageminpar;
                   9619:   agelim=agemaxpar;
1.180     brouard  9620: 
1.227     brouard  9621:   /* i1=pow(2,ncoveff); */
1.234     brouard  9622:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9623:   if (cptcovn < 1){i1=1;}
1.180     brouard  9624: 
1.238     brouard  9625:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9626:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9627:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9628:        continue;
1.235     brouard  9629: 
1.238     brouard  9630:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9631:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9632:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9633:       /* k=k+1; */
                   9634:       /* to clean */
                   9635:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9636:       fprintf(ficrespl,"#******");
                   9637:       printf("#******");
                   9638:       fprintf(ficlog,"#******");
                   9639:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9640:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9641:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9642:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9643:       }
                   9644:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9645:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9646:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9647:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9648:       }
                   9649:       fprintf(ficrespl,"******\n");
                   9650:       printf("******\n");
                   9651:       fprintf(ficlog,"******\n");
                   9652:       if(invalidvarcomb[k]){
                   9653:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9654:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9655:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9656:        continue;
                   9657:       }
1.219     brouard  9658: 
1.238     brouard  9659:       fprintf(ficrespl,"#Age ");
                   9660:       for(j=1;j<=cptcoveff;j++) {
                   9661:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9662:       }
                   9663:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9664:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9665:     
1.238     brouard  9666:       for (age=agebase; age<=agelim; age++){
                   9667:        /* for (age=agebase; age<=agebase; age++){ */
                   9668:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9669:        fprintf(ficrespl,"%.0f ",age );
                   9670:        for(j=1;j<=cptcoveff;j++)
                   9671:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9672:        tot=0.;
                   9673:        for(i=1; i<=nlstate;i++){
                   9674:          tot +=  prlim[i][i];
                   9675:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9676:        }
                   9677:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9678:       } /* Age */
                   9679:       /* was end of cptcod */
                   9680:     } /* cptcov */
                   9681:   } /* nres */
1.219     brouard  9682:   return 0;
1.180     brouard  9683: }
                   9684: 
1.218     brouard  9685: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9686:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9687:        
                   9688:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9689:    * at any age between ageminpar and agemaxpar
                   9690:         */
1.235     brouard  9691:   int i, j, k, i1, nres=0 ;
1.217     brouard  9692:   /* double ftolpl = 1.e-10; */
                   9693:   double age, agebase, agelim;
                   9694:   double tot;
1.218     brouard  9695:   /* double ***mobaverage; */
                   9696:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9697: 
                   9698:   strcpy(fileresplb,"PLB_");
                   9699:   strcat(fileresplb,fileresu);
                   9700:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9701:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9702:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9703:   }
                   9704:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9705:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9706:   pstamp(ficresplb);
                   9707:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9708:   fprintf(ficresplb,"#Age ");
                   9709:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9710:   fprintf(ficresplb,"\n");
                   9711:   
1.218     brouard  9712:   
                   9713:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9714:   
                   9715:   agebase=ageminpar;
                   9716:   agelim=agemaxpar;
                   9717:   
                   9718:   
1.227     brouard  9719:   i1=pow(2,cptcoveff);
1.218     brouard  9720:   if (cptcovn < 1){i1=1;}
1.227     brouard  9721:   
1.238     brouard  9722:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9723:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9724:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9725:        continue;
                   9726:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9727:       fprintf(ficresplb,"#******");
                   9728:       printf("#******");
                   9729:       fprintf(ficlog,"#******");
                   9730:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9731:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9732:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9733:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9734:       }
                   9735:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9736:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9737:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9738:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9739:       }
                   9740:       fprintf(ficresplb,"******\n");
                   9741:       printf("******\n");
                   9742:       fprintf(ficlog,"******\n");
                   9743:       if(invalidvarcomb[k]){
                   9744:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9745:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9746:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9747:        continue;
                   9748:       }
1.218     brouard  9749:     
1.238     brouard  9750:       fprintf(ficresplb,"#Age ");
                   9751:       for(j=1;j<=cptcoveff;j++) {
                   9752:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9753:       }
                   9754:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9755:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9756:     
                   9757:     
1.238     brouard  9758:       for (age=agebase; age<=agelim; age++){
                   9759:        /* for (age=agebase; age<=agebase; age++){ */
                   9760:        if(mobilavproj > 0){
                   9761:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9762:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9763:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9764:        }else if (mobilavproj == 0){
                   9765:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9766:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9767:          exit(1);
                   9768:        }else{
                   9769:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9770:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9771:        }
                   9772:        fprintf(ficresplb,"%.0f ",age );
                   9773:        for(j=1;j<=cptcoveff;j++)
                   9774:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9775:        tot=0.;
                   9776:        for(i=1; i<=nlstate;i++){
                   9777:          tot +=  bprlim[i][i];
                   9778:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9779:        }
                   9780:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9781:       } /* Age */
                   9782:       /* was end of cptcod */
1.255     brouard  9783:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9784:     } /* end of any combination */
                   9785:   } /* end of nres */  
1.218     brouard  9786:   /* hBijx(p, bage, fage); */
                   9787:   /* fclose(ficrespijb); */
                   9788:   
                   9789:   return 0;
1.217     brouard  9790: }
1.218     brouard  9791:  
1.180     brouard  9792: int hPijx(double *p, int bage, int fage){
                   9793:     /*------------- h Pij x at various ages ------------*/
                   9794: 
                   9795:   int stepsize;
                   9796:   int agelim;
                   9797:   int hstepm;
                   9798:   int nhstepm;
1.235     brouard  9799:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9800: 
                   9801:   double agedeb;
                   9802:   double ***p3mat;
                   9803: 
1.201     brouard  9804:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9805:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9806:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9807:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9808:     }
                   9809:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9810:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9811:   
                   9812:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9813:     /*if (stepm<=24) stepsize=2;*/
                   9814: 
                   9815:     agelim=AGESUP;
                   9816:     hstepm=stepsize*YEARM; /* Every year of age */
                   9817:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9818:                
1.180     brouard  9819:     /* hstepm=1;   aff par mois*/
                   9820:     pstamp(ficrespij);
                   9821:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9822:     i1= pow(2,cptcoveff);
1.218     brouard  9823:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9824:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9825:                /*      k=k+1;  */
1.235     brouard  9826:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9827:     for(k=1; k<=i1;k++){
1.253     brouard  9828:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9829:        continue;
1.183     brouard  9830:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9831:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9832:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9833:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9834:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9835:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9836:       }
1.183     brouard  9837:       fprintf(ficrespij,"******\n");
                   9838:       
                   9839:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9840:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9841:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9842:        
                   9843:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9844:        
1.183     brouard  9845:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9846:        oldm=oldms;savm=savms;
1.235     brouard  9847:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9848:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9849:        for(i=1; i<=nlstate;i++)
                   9850:          for(j=1; j<=nlstate+ndeath;j++)
                   9851:            fprintf(ficrespij," %1d-%1d",i,j);
                   9852:        fprintf(ficrespij,"\n");
                   9853:        for (h=0; h<=nhstepm; h++){
                   9854:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9855:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9856:          for(i=1; i<=nlstate;i++)
                   9857:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9858:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9859:          fprintf(ficrespij,"\n");
                   9860:        }
1.183     brouard  9861:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9862:        fprintf(ficrespij,"\n");
                   9863:       }
1.180     brouard  9864:       /*}*/
                   9865:     }
1.218     brouard  9866:     return 0;
1.180     brouard  9867: }
1.218     brouard  9868:  
                   9869:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9870:     /*------------- h Bij x at various ages ------------*/
                   9871: 
                   9872:   int stepsize;
1.218     brouard  9873:   /* int agelim; */
                   9874:        int ageminl;
1.217     brouard  9875:   int hstepm;
                   9876:   int nhstepm;
1.238     brouard  9877:   int h, i, i1, j, k, nres;
1.218     brouard  9878:        
1.217     brouard  9879:   double agedeb;
                   9880:   double ***p3mat;
1.218     brouard  9881:        
                   9882:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9883:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9884:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9885:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9886:   }
                   9887:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9888:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9889:   
                   9890:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9891:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9892:   
1.218     brouard  9893:   /* agelim=AGESUP; */
                   9894:   ageminl=30;
                   9895:   hstepm=stepsize*YEARM; /* Every year of age */
                   9896:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9897:   
                   9898:   /* hstepm=1;   aff par mois*/
                   9899:   pstamp(ficrespijb);
1.255     brouard  9900:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9901:   i1= pow(2,cptcoveff);
1.218     brouard  9902:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9903:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9904:   /*   k=k+1;  */
1.238     brouard  9905:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9906:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9907:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9908:        continue;
                   9909:       fprintf(ficrespijb,"\n#****** ");
                   9910:       for(j=1;j<=cptcoveff;j++)
                   9911:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9912:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9913:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9914:       }
                   9915:       fprintf(ficrespijb,"******\n");
1.264     brouard  9916:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  9917:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9918:        continue;
                   9919:       }
                   9920:       
                   9921:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9922:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9923:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9924:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9925:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9926:        
                   9927:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9928:        
                   9929:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9930:        /* oldm=oldms;savm=savms; */
                   9931:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9932:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9933:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9934:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9935:        for(i=1; i<=nlstate;i++)
                   9936:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9937:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9938:        fprintf(ficrespijb,"\n");
1.238     brouard  9939:        for (h=0; h<=nhstepm; h++){
                   9940:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9941:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9942:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9943:          for(i=1; i<=nlstate;i++)
                   9944:            for(j=1; j<=nlstate+ndeath;j++)
                   9945:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9946:          fprintf(ficrespijb,"\n");
                   9947:        }
                   9948:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9949:        fprintf(ficrespijb,"\n");
                   9950:       } /* end age deb */
                   9951:     } /* end combination */
                   9952:   } /* end nres */
1.218     brouard  9953:   return 0;
                   9954:  } /*  hBijx */
1.217     brouard  9955: 
1.180     brouard  9956: 
1.136     brouard  9957: /***********************************************/
                   9958: /**************** Main Program *****************/
                   9959: /***********************************************/
                   9960: 
                   9961: int main(int argc, char *argv[])
                   9962: {
                   9963: #ifdef GSL
                   9964:   const gsl_multimin_fminimizer_type *T;
                   9965:   size_t iteri = 0, it;
                   9966:   int rval = GSL_CONTINUE;
                   9967:   int status = GSL_SUCCESS;
                   9968:   double ssval;
                   9969: #endif
                   9970:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9971:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9972:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9973:   int jj, ll, li, lj, lk;
1.136     brouard  9974:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9975:   int num_filled;
1.136     brouard  9976:   int itimes;
                   9977:   int NDIM=2;
                   9978:   int vpopbased=0;
1.235     brouard  9979:   int nres=0;
1.258     brouard  9980:   int endishere=0;
1.136     brouard  9981: 
1.164     brouard  9982:   char ca[32], cb[32];
1.136     brouard  9983:   /*  FILE *fichtm; *//* Html File */
                   9984:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9985:   struct stat info;
1.191     brouard  9986:   double agedeb=0.;
1.194     brouard  9987: 
                   9988:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9989:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9990: 
1.165     brouard  9991:   double fret;
1.191     brouard  9992:   double dum=0.; /* Dummy variable */
1.136     brouard  9993:   double ***p3mat;
1.218     brouard  9994:   /* double ***mobaverage; */
1.164     brouard  9995: 
                   9996:   char line[MAXLINE];
1.197     brouard  9997:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9998: 
1.234     brouard  9999:   char  modeltemp[MAXLINE];
1.230     brouard  10000:   char resultline[MAXLINE];
                   10001:   
1.136     brouard  10002:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10003:   char *tok, *val; /* pathtot */
1.136     brouard  10004:   int firstobs=1, lastobs=10;
1.195     brouard  10005:   int c,  h , cpt, c2;
1.191     brouard  10006:   int jl=0;
                   10007:   int i1, j1, jk, stepsize=0;
1.194     brouard  10008:   int count=0;
                   10009: 
1.164     brouard  10010:   int *tab; 
1.136     brouard  10011:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10012:   int backcast=0;
1.136     brouard  10013:   int mobilav=0,popforecast=0;
1.191     brouard  10014:   int hstepm=0, nhstepm=0;
1.136     brouard  10015:   int agemortsup;
                   10016:   float  sumlpop=0.;
                   10017:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10018:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10019: 
1.191     brouard  10020:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10021:   double ftolpl=FTOL;
                   10022:   double **prlim;
1.217     brouard  10023:   double **bprlim;
1.136     brouard  10024:   double ***param; /* Matrix of parameters */
1.251     brouard  10025:   double ***paramstart; /* Matrix of starting parameter values */
                   10026:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10027:   double **matcov; /* Matrix of covariance */
1.203     brouard  10028:   double **hess; /* Hessian matrix */
1.136     brouard  10029:   double ***delti3; /* Scale */
                   10030:   double *delti; /* Scale */
                   10031:   double ***eij, ***vareij;
                   10032:   double **varpl; /* Variances of prevalence limits by age */
                   10033:   double *epj, vepp;
1.164     brouard  10034: 
1.136     brouard  10035:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  10036:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   10037: 
1.136     brouard  10038:   double **ximort;
1.145     brouard  10039:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10040:   int *dcwave;
                   10041: 
1.164     brouard  10042:   char z[1]="c";
1.136     brouard  10043: 
                   10044:   /*char  *strt;*/
                   10045:   char strtend[80];
1.126     brouard  10046: 
1.164     brouard  10047: 
1.126     brouard  10048: /*   setlocale (LC_ALL, ""); */
                   10049: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10050: /*   textdomain (PACKAGE); */
                   10051: /*   setlocale (LC_CTYPE, ""); */
                   10052: /*   setlocale (LC_MESSAGES, ""); */
                   10053: 
                   10054:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10055:   rstart_time = time(NULL);  
                   10056:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10057:   start_time = *localtime(&rstart_time);
1.126     brouard  10058:   curr_time=start_time;
1.157     brouard  10059:   /*tml = *localtime(&start_time.tm_sec);*/
                   10060:   /* strcpy(strstart,asctime(&tml)); */
                   10061:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10062: 
                   10063: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10064: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10065: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10066: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10067: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10068: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10069: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10070: /*   strt=asctime(&tmg); */
                   10071: /*   printf("Time(after) =%s",strstart);  */
                   10072: /*  (void) time (&time_value);
                   10073: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10074: *  tm = *localtime(&time_value);
                   10075: *  strstart=asctime(&tm);
                   10076: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10077: */
                   10078: 
                   10079:   nberr=0; /* Number of errors and warnings */
                   10080:   nbwarn=0;
1.184     brouard  10081: #ifdef WIN32
                   10082:   _getcwd(pathcd, size);
                   10083: #else
1.126     brouard  10084:   getcwd(pathcd, size);
1.184     brouard  10085: #endif
1.191     brouard  10086:   syscompilerinfo(0);
1.196     brouard  10087:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10088:   if(argc <=1){
                   10089:     printf("\nEnter the parameter file name: ");
1.205     brouard  10090:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10091:       printf("ERROR Empty parameter file name\n");
                   10092:       goto end;
                   10093:     }
1.126     brouard  10094:     i=strlen(pathr);
                   10095:     if(pathr[i-1]=='\n')
                   10096:       pathr[i-1]='\0';
1.156     brouard  10097:     i=strlen(pathr);
1.205     brouard  10098:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10099:       pathr[i-1]='\0';
1.205     brouard  10100:     }
                   10101:     i=strlen(pathr);
                   10102:     if( i==0 ){
                   10103:       printf("ERROR Empty parameter file name\n");
                   10104:       goto end;
                   10105:     }
                   10106:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10107:       printf("Pathr |%s|\n",pathr);
                   10108:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10109:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10110:       strcpy (pathtot, val);
                   10111:       if(pathr[0] == '\0') break; /* Dirty */
                   10112:     }
                   10113:   }
                   10114:   else{
                   10115:     strcpy(pathtot,argv[1]);
                   10116:   }
                   10117:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10118:   /*cygwin_split_path(pathtot,path,optionfile);
                   10119:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10120:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10121: 
                   10122:   /* Split argv[0], imach program to get pathimach */
                   10123:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10124:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10125:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10126:  /*   strcpy(pathimach,argv[0]); */
                   10127:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10128:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10129:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10130: #ifdef WIN32
                   10131:   _chdir(path); /* Can be a relative path */
                   10132:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10133: #else
1.126     brouard  10134:   chdir(path); /* Can be a relative path */
1.184     brouard  10135:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10136: #endif
                   10137:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10138:   strcpy(command,"mkdir ");
                   10139:   strcat(command,optionfilefiname);
                   10140:   if((outcmd=system(command)) != 0){
1.169     brouard  10141:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10142:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10143:     /* fclose(ficlog); */
                   10144: /*     exit(1); */
                   10145:   }
                   10146: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10147: /*     perror("mkdir"); */
                   10148: /*   } */
                   10149: 
                   10150:   /*-------- arguments in the command line --------*/
                   10151: 
1.186     brouard  10152:   /* Main Log file */
1.126     brouard  10153:   strcat(filelog, optionfilefiname);
                   10154:   strcat(filelog,".log");    /* */
                   10155:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10156:     printf("Problem with logfile %s\n",filelog);
                   10157:     goto end;
                   10158:   }
                   10159:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10160:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10161:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10162:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10163:  path=%s \n\
                   10164:  optionfile=%s\n\
                   10165:  optionfilext=%s\n\
1.156     brouard  10166:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10167: 
1.197     brouard  10168:   syscompilerinfo(1);
1.167     brouard  10169: 
1.126     brouard  10170:   printf("Local time (at start):%s",strstart);
                   10171:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10172:   fflush(ficlog);
                   10173: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10174: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10175: 
                   10176:   /* */
                   10177:   strcpy(fileres,"r");
                   10178:   strcat(fileres, optionfilefiname);
1.201     brouard  10179:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10180:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10181:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10182: 
1.186     brouard  10183:   /* Main ---------arguments file --------*/
1.126     brouard  10184: 
                   10185:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10186:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10187:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10188:     fflush(ficlog);
1.149     brouard  10189:     /* goto end; */
                   10190:     exit(70); 
1.126     brouard  10191:   }
                   10192: 
                   10193: 
                   10194: 
                   10195:   strcpy(filereso,"o");
1.201     brouard  10196:   strcat(filereso,fileresu);
1.126     brouard  10197:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10198:     printf("Problem with Output resultfile: %s\n", filereso);
                   10199:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10200:     fflush(ficlog);
                   10201:     goto end;
                   10202:   }
                   10203: 
                   10204:   /* Reads comments: lines beginning with '#' */
                   10205:   numlinepar=0;
1.197     brouard  10206: 
                   10207:     /* First parameter line */
                   10208:   while(fgets(line, MAXLINE, ficpar)) {
                   10209:     /* If line starts with a # it is a comment */
                   10210:     if (line[0] == '#') {
                   10211:       numlinepar++;
                   10212:       fputs(line,stdout);
                   10213:       fputs(line,ficparo);
                   10214:       fputs(line,ficlog);
                   10215:       continue;
                   10216:     }else
                   10217:       break;
                   10218:   }
                   10219:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10220:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10221:     if (num_filled != 5) {
                   10222:       printf("Should be 5 parameters\n");
                   10223:     }
1.126     brouard  10224:     numlinepar++;
1.197     brouard  10225:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10226:   }
                   10227:   /* Second parameter line */
                   10228:   while(fgets(line, MAXLINE, ficpar)) {
                   10229:     /* If line starts with a # it is a comment */
                   10230:     if (line[0] == '#') {
                   10231:       numlinepar++;
                   10232:       fputs(line,stdout);
                   10233:       fputs(line,ficparo);
                   10234:       fputs(line,ficlog);
                   10235:       continue;
                   10236:     }else
                   10237:       break;
                   10238:   }
1.223     brouard  10239:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10240:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10241:     if (num_filled != 11) {
                   10242:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10243:       printf("but line=%s\n",line);
1.197     brouard  10244:     }
1.223     brouard  10245:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10246:   }
1.203     brouard  10247:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10248:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10249:   /* Third parameter line */
                   10250:   while(fgets(line, MAXLINE, ficpar)) {
                   10251:     /* If line starts with a # it is a comment */
                   10252:     if (line[0] == '#') {
                   10253:       numlinepar++;
                   10254:       fputs(line,stdout);
                   10255:       fputs(line,ficparo);
                   10256:       fputs(line,ficlog);
                   10257:       continue;
                   10258:     }else
                   10259:       break;
                   10260:   }
1.201     brouard  10261:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10262:     if (num_filled == 0){
                   10263:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10264:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10265:       model[0]='\0';
                   10266:       goto end;
                   10267:     } else if (num_filled != 1){
1.197     brouard  10268:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10269:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10270:       model[0]='\0';
                   10271:       goto end;
                   10272:     }
                   10273:     else{
                   10274:       if (model[0]=='+'){
                   10275:        for(i=1; i<=strlen(model);i++)
                   10276:          modeltemp[i-1]=model[i];
1.201     brouard  10277:        strcpy(model,modeltemp); 
1.197     brouard  10278:       }
                   10279:     }
1.199     brouard  10280:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10281:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10282:   }
                   10283:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10284:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10285:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10286:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10287:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10288:   fflush(ficlog);
1.190     brouard  10289:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10290:   if(model[0]=='#'){
1.187     brouard  10291:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10292:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10293:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10294:     if(mle != -1){
                   10295:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10296:       exit(1);
                   10297:     }
                   10298:   }
1.126     brouard  10299:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10300:     ungetc(c,ficpar);
                   10301:     fgets(line, MAXLINE, ficpar);
                   10302:     numlinepar++;
1.195     brouard  10303:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10304:       z[0]=line[1];
                   10305:     }
                   10306:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10307:     fputs(line, stdout);
                   10308:     //puts(line);
1.126     brouard  10309:     fputs(line,ficparo);
                   10310:     fputs(line,ficlog);
                   10311:   }
                   10312:   ungetc(c,ficpar);
                   10313: 
                   10314:    
1.145     brouard  10315:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10316:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10317:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10318:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10319:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10320:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10321:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10322:   */
                   10323:   if (strlen(model)>1) 
1.187     brouard  10324:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10325:   else
1.187     brouard  10326:     ncovmodel=2; /* Constant and age */
1.133     brouard  10327:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10328:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10329:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10330:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10331:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10332:     fflush(stdout);
                   10333:     fclose (ficlog);
                   10334:     goto end;
                   10335:   }
1.126     brouard  10336:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10337:   delti=delti3[1][1];
                   10338:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10339:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10340: /* We could also provide initial parameters values giving by simple logistic regression 
                   10341:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10342:       /* for(i=1;i<nlstate;i++){ */
                   10343:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10344:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10345:       /* } */
1.126     brouard  10346:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10347:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10348:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10349:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10350:     fclose (ficparo);
                   10351:     fclose (ficlog);
                   10352:     goto end;
                   10353:     exit(0);
1.220     brouard  10354:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10355:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10356:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10357:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10358:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10359:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10360:     hess=matrix(1,npar,1,npar);
1.220     brouard  10361:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10362:     /* Read guessed parameters */
1.126     brouard  10363:     /* Reads comments: lines beginning with '#' */
                   10364:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10365:       ungetc(c,ficpar);
                   10366:       fgets(line, MAXLINE, ficpar);
                   10367:       numlinepar++;
1.141     brouard  10368:       fputs(line,stdout);
1.126     brouard  10369:       fputs(line,ficparo);
                   10370:       fputs(line,ficlog);
                   10371:     }
                   10372:     ungetc(c,ficpar);
                   10373:     
                   10374:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10375:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10376:     for(i=1; i <=nlstate; i++){
1.234     brouard  10377:       j=0;
1.126     brouard  10378:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10379:        if(jj==i) continue;
                   10380:        j++;
                   10381:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10382:        if ((i1 != i) || (j1 != jj)){
                   10383:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10384: It might be a problem of design; if ncovcol and the model are correct\n \
                   10385: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10386:          exit(1);
                   10387:        }
                   10388:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10389:        if(mle==1)
                   10390:          printf("%1d%1d",i,jj);
                   10391:        fprintf(ficlog,"%1d%1d",i,jj);
                   10392:        for(k=1; k<=ncovmodel;k++){
                   10393:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10394:          if(mle==1){
                   10395:            printf(" %lf",param[i][j][k]);
                   10396:            fprintf(ficlog," %lf",param[i][j][k]);
                   10397:          }
                   10398:          else
                   10399:            fprintf(ficlog," %lf",param[i][j][k]);
                   10400:          fprintf(ficparo," %lf",param[i][j][k]);
                   10401:        }
                   10402:        fscanf(ficpar,"\n");
                   10403:        numlinepar++;
                   10404:        if(mle==1)
                   10405:          printf("\n");
                   10406:        fprintf(ficlog,"\n");
                   10407:        fprintf(ficparo,"\n");
1.126     brouard  10408:       }
                   10409:     }  
                   10410:     fflush(ficlog);
1.234     brouard  10411:     
1.251     brouard  10412:     /* Reads parameters values */
1.126     brouard  10413:     p=param[1][1];
1.251     brouard  10414:     pstart=paramstart[1][1];
1.126     brouard  10415:     
                   10416:     /* Reads comments: lines beginning with '#' */
                   10417:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10418:       ungetc(c,ficpar);
                   10419:       fgets(line, MAXLINE, ficpar);
                   10420:       numlinepar++;
1.141     brouard  10421:       fputs(line,stdout);
1.126     brouard  10422:       fputs(line,ficparo);
                   10423:       fputs(line,ficlog);
                   10424:     }
                   10425:     ungetc(c,ficpar);
                   10426: 
                   10427:     for(i=1; i <=nlstate; i++){
                   10428:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10429:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10430:        if ( (i1-i) * (j1-j) != 0){
                   10431:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10432:          exit(1);
                   10433:        }
                   10434:        printf("%1d%1d",i,j);
                   10435:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10436:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10437:        for(k=1; k<=ncovmodel;k++){
                   10438:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10439:          printf(" %le",delti3[i][j][k]);
                   10440:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10441:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10442:        }
                   10443:        fscanf(ficpar,"\n");
                   10444:        numlinepar++;
                   10445:        printf("\n");
                   10446:        fprintf(ficparo,"\n");
                   10447:        fprintf(ficlog,"\n");
1.126     brouard  10448:       }
                   10449:     }
                   10450:     fflush(ficlog);
1.234     brouard  10451:     
1.145     brouard  10452:     /* Reads covariance matrix */
1.126     brouard  10453:     delti=delti3[1][1];
1.220     brouard  10454:                
                   10455:                
1.126     brouard  10456:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10457:                
1.126     brouard  10458:     /* Reads comments: lines beginning with '#' */
                   10459:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10460:       ungetc(c,ficpar);
                   10461:       fgets(line, MAXLINE, ficpar);
                   10462:       numlinepar++;
1.141     brouard  10463:       fputs(line,stdout);
1.126     brouard  10464:       fputs(line,ficparo);
                   10465:       fputs(line,ficlog);
                   10466:     }
                   10467:     ungetc(c,ficpar);
1.220     brouard  10468:                
1.126     brouard  10469:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10470:     hess=matrix(1,npar,1,npar);
1.131     brouard  10471:     for(i=1; i <=npar; i++)
                   10472:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10473:                
1.194     brouard  10474:     /* Scans npar lines */
1.126     brouard  10475:     for(i=1; i <=npar; i++){
1.226     brouard  10476:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10477:       if(count != 3){
1.226     brouard  10478:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10479: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10480: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10481:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10482: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10483: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10484:        exit(1);
1.220     brouard  10485:       }else{
1.226     brouard  10486:        if(mle==1)
                   10487:          printf("%1d%1d%d",i1,j1,jk);
                   10488:       }
                   10489:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10490:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10491:       for(j=1; j <=i; j++){
1.226     brouard  10492:        fscanf(ficpar," %le",&matcov[i][j]);
                   10493:        if(mle==1){
                   10494:          printf(" %.5le",matcov[i][j]);
                   10495:        }
                   10496:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10497:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10498:       }
                   10499:       fscanf(ficpar,"\n");
                   10500:       numlinepar++;
                   10501:       if(mle==1)
1.220     brouard  10502:                                printf("\n");
1.126     brouard  10503:       fprintf(ficlog,"\n");
                   10504:       fprintf(ficparo,"\n");
                   10505:     }
1.194     brouard  10506:     /* End of read covariance matrix npar lines */
1.126     brouard  10507:     for(i=1; i <=npar; i++)
                   10508:       for(j=i+1;j<=npar;j++)
1.226     brouard  10509:        matcov[i][j]=matcov[j][i];
1.126     brouard  10510:     
                   10511:     if(mle==1)
                   10512:       printf("\n");
                   10513:     fprintf(ficlog,"\n");
                   10514:     
                   10515:     fflush(ficlog);
                   10516:     
                   10517:     /*-------- Rewriting parameter file ----------*/
                   10518:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10519:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10520:     strcat(rfileres,".");    /* */
                   10521:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10522:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10523:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10524:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10525:     }
                   10526:     fprintf(ficres,"#%s\n",version);
                   10527:   }    /* End of mle != -3 */
1.218     brouard  10528:   
1.186     brouard  10529:   /*  Main data
                   10530:    */
1.126     brouard  10531:   n= lastobs;
                   10532:   num=lvector(1,n);
                   10533:   moisnais=vector(1,n);
                   10534:   annais=vector(1,n);
                   10535:   moisdc=vector(1,n);
                   10536:   andc=vector(1,n);
1.220     brouard  10537:   weight=vector(1,n);
1.126     brouard  10538:   agedc=vector(1,n);
                   10539:   cod=ivector(1,n);
1.220     brouard  10540:   for(i=1;i<=n;i++){
1.234     brouard  10541:     num[i]=0;
                   10542:     moisnais[i]=0;
                   10543:     annais[i]=0;
                   10544:     moisdc[i]=0;
                   10545:     andc[i]=0;
                   10546:     agedc[i]=0;
                   10547:     cod[i]=0;
                   10548:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10549:   }
1.126     brouard  10550:   mint=matrix(1,maxwav,1,n);
                   10551:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10552:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10553:   tab=ivector(1,NCOVMAX);
1.144     brouard  10554:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10555:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10556: 
1.136     brouard  10557:   /* Reads data from file datafile */
                   10558:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10559:     goto end;
                   10560: 
                   10561:   /* Calculation of the number of parameters from char model */
1.234     brouard  10562:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10563:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10564:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10565:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10566:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10567:   */
                   10568:   
                   10569:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10570:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10571:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10572:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10573:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10574:   TvarF=ivector(1,NCOVMAX); /*  */
                   10575:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10576:   TvarV=ivector(1,NCOVMAX); /*  */
                   10577:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10578:   TvarA=ivector(1,NCOVMAX); /*  */
                   10579:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10580:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10581:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10582:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10583:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10584:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10585:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10586:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10587:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10588: 
1.230     brouard  10589:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10590:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10591:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10592:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10593:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10594:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10595:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10596:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10597:   */
                   10598:   /* For model-covariate k tells which data-covariate to use but
                   10599:     because this model-covariate is a construction we invent a new column
                   10600:     ncovcol + k1
                   10601:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10602:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10603:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10604:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10605:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10606:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10607:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10608:   */
1.145     brouard  10609:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10610:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10611:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10612:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10613:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10614:                         4 covariates (3 plus signs)
                   10615:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10616:                      */  
1.230     brouard  10617:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10618:                                * individual dummy, fixed or varying:
                   10619:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10620:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10621:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10622:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10623:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10624:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10625:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10626:                                * individual quantitative, fixed or varying:
                   10627:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10628:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10629:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10630: /* Main decodemodel */
                   10631: 
1.187     brouard  10632: 
1.223     brouard  10633:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10634:     goto end;
                   10635: 
1.137     brouard  10636:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10637:     nbwarn++;
                   10638:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10639:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10640:   }
1.136     brouard  10641:     /*  if(mle==1){*/
1.137     brouard  10642:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10643:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10644:   }
                   10645: 
                   10646:     /*-calculation of age at interview from date of interview and age at death -*/
                   10647:   agev=matrix(1,maxwav,1,imx);
                   10648: 
                   10649:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10650:     goto end;
                   10651: 
1.126     brouard  10652: 
1.136     brouard  10653:   agegomp=(int)agemin;
                   10654:   free_vector(moisnais,1,n);
                   10655:   free_vector(annais,1,n);
1.126     brouard  10656:   /* free_matrix(mint,1,maxwav,1,n);
                   10657:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10658:   /* free_vector(moisdc,1,n); */
                   10659:   /* free_vector(andc,1,n); */
1.145     brouard  10660:   /* */
                   10661:   
1.126     brouard  10662:   wav=ivector(1,imx);
1.214     brouard  10663:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10664:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10665:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10666:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10667:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10668:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10669:    
                   10670:   /* Concatenates waves */
1.214     brouard  10671:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10672:      Death is a valid wave (if date is known).
                   10673:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10674:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10675:      and mw[mi+1][i]. dh depends on stepm.
                   10676:   */
                   10677: 
1.126     brouard  10678:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10679:   /* Concatenates waves */
1.145     brouard  10680:  
1.215     brouard  10681:   free_vector(moisdc,1,n);
                   10682:   free_vector(andc,1,n);
                   10683: 
1.126     brouard  10684:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10685:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10686:   ncodemax[1]=1;
1.145     brouard  10687:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10688:   cptcoveff=0;
1.220     brouard  10689:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10690:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10691:   }
                   10692:   
                   10693:   ncovcombmax=pow(2,cptcoveff);
                   10694:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10695:   for(i=1;i<ncovcombmax;i++)
                   10696:     invalidvarcomb[i]=0;
                   10697:   
1.211     brouard  10698:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10699:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10700:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10701:   
1.200     brouard  10702:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10703:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10704:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10705:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10706:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10707:    * (currently 0 or 1) in the data.
                   10708:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10709:    * corresponding modality (h,j).
                   10710:    */
                   10711: 
1.145     brouard  10712:   h=0;
                   10713:   /*if (cptcovn > 0) */
1.126     brouard  10714:   m=pow(2,cptcoveff);
                   10715:  
1.144     brouard  10716:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10717:           * For k=4 covariates, h goes from 1 to m=2**k
                   10718:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10719:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10720:           *     h\k   1     2     3     4
1.143     brouard  10721:           *______________________________  
                   10722:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10723:           *     2     2     1     1     1
                   10724:           *     3 i=2 1     2     1     1
                   10725:           *     4     2     2     1     1
                   10726:           *     5 i=3 1 i=2 1     2     1
                   10727:           *     6     2     1     2     1
                   10728:           *     7 i=4 1     2     2     1
                   10729:           *     8     2     2     2     1
1.197     brouard  10730:           *     9 i=5 1 i=3 1 i=2 1     2
                   10731:           *    10     2     1     1     2
                   10732:           *    11 i=6 1     2     1     2
                   10733:           *    12     2     2     1     2
                   10734:           *    13 i=7 1 i=4 1     2     2    
                   10735:           *    14     2     1     2     2
                   10736:           *    15 i=8 1     2     2     2
                   10737:           *    16     2     2     2     2
1.143     brouard  10738:           */
1.212     brouard  10739:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10740:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10741:      * and the value of each covariate?
                   10742:      * V1=1, V2=1, V3=2, V4=1 ?
                   10743:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10744:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10745:      * In order to get the real value in the data, we use nbcode
                   10746:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10747:      * We are keeping this crazy system in order to be able (in the future?) 
                   10748:      * to have more than 2 values (0 or 1) for a covariate.
                   10749:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10750:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10751:      *              bbbbbbbb
                   10752:      *              76543210     
                   10753:      *   h-1        00000101 (6-1=5)
1.219     brouard  10754:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10755:      *           &
                   10756:      *     1        00000001 (1)
1.219     brouard  10757:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10758:      *          +1= 00000001 =1 
1.211     brouard  10759:      *
                   10760:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10761:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10762:      *    >>k'            11
                   10763:      *          &   00000001
                   10764:      *            = 00000001
                   10765:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10766:      * Reverse h=6 and m=16?
                   10767:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10768:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10769:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10770:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10771:      * V3=decodtabm(14,3,2**4)=2
                   10772:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10773:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10774:      *          &1 000000001
                   10775:      *           = 000000001
                   10776:      *         +1= 000000010 =2
                   10777:      *                  2211
                   10778:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10779:      *                  V3=2
1.220     brouard  10780:                 * codtabm and decodtabm are identical
1.211     brouard  10781:      */
                   10782: 
1.145     brouard  10783: 
                   10784:  free_ivector(Ndum,-1,NCOVMAX);
                   10785: 
                   10786: 
1.126     brouard  10787:     
1.186     brouard  10788:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10789:   strcpy(optionfilegnuplot,optionfilefiname);
                   10790:   if(mle==-3)
1.201     brouard  10791:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10792:   strcat(optionfilegnuplot,".gp");
                   10793: 
                   10794:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10795:     printf("Problem with file %s",optionfilegnuplot);
                   10796:   }
                   10797:   else{
1.204     brouard  10798:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10799:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10800:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10801:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10802:   }
                   10803:   /*  fclose(ficgp);*/
1.186     brouard  10804: 
                   10805: 
                   10806:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10807: 
                   10808:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10809:   if(mle==-3)
1.201     brouard  10810:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10811:   strcat(optionfilehtm,".htm");
                   10812:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10813:     printf("Problem with %s \n",optionfilehtm);
                   10814:     exit(0);
1.126     brouard  10815:   }
                   10816: 
                   10817:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10818:   strcat(optionfilehtmcov,"-cov.htm");
                   10819:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10820:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10821:   }
                   10822:   else{
                   10823:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10824: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10825: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10826:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10827:   }
                   10828: 
1.213     brouard  10829:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10830: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10831: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10832: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10833: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10834: \n\
                   10835: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10836:  <ul><li><h4>Parameter files</h4>\n\
                   10837:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10838:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10839:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10840:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10841:  - Date and time at start: %s</ul>\n",\
                   10842:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10843:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10844:          fileres,fileres,\
                   10845:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10846:   fflush(fichtm);
                   10847: 
                   10848:   strcpy(pathr,path);
                   10849:   strcat(pathr,optionfilefiname);
1.184     brouard  10850: #ifdef WIN32
                   10851:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10852: #else
1.126     brouard  10853:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10854: #endif
                   10855:          
1.126     brouard  10856:   
1.220     brouard  10857:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10858:                 and for any valid combination of covariates
1.126     brouard  10859:      and prints on file fileres'p'. */
1.251     brouard  10860:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10861:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10862: 
                   10863:   fprintf(fichtm,"\n");
                   10864:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10865: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10866: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10867:          imx,agemin,agemax,jmin,jmax,jmean);
                   10868:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10869:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10870:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10871:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10872:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10873: 
1.126     brouard  10874:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10875:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10876:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10877: 
                   10878:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10879:   /* For mortality only */
1.126     brouard  10880:   if (mle==-3){
1.136     brouard  10881:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10882:     for(i=1;i<=NDIM;i++)
                   10883:       for(j=1;j<=NDIM;j++)
                   10884:        ximort[i][j]=0.;
1.186     brouard  10885:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10886:     cens=ivector(1,n);
                   10887:     ageexmed=vector(1,n);
                   10888:     agecens=vector(1,n);
                   10889:     dcwave=ivector(1,n);
1.223     brouard  10890:                
1.126     brouard  10891:     for (i=1; i<=imx; i++){
                   10892:       dcwave[i]=-1;
                   10893:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10894:        if (s[m][i]>nlstate) {
                   10895:          dcwave[i]=m;
                   10896:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10897:          break;
                   10898:        }
1.126     brouard  10899:     }
1.226     brouard  10900:     
1.126     brouard  10901:     for (i=1; i<=imx; i++) {
                   10902:       if (wav[i]>0){
1.226     brouard  10903:        ageexmed[i]=agev[mw[1][i]][i];
                   10904:        j=wav[i];
                   10905:        agecens[i]=1.; 
                   10906:        
                   10907:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10908:          agecens[i]=agev[mw[j][i]][i];
                   10909:          cens[i]= 1;
                   10910:        }else if (ageexmed[i]< 1) 
                   10911:          cens[i]= -1;
                   10912:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10913:          cens[i]=0 ;
1.126     brouard  10914:       }
                   10915:       else cens[i]=-1;
                   10916:     }
                   10917:     
                   10918:     for (i=1;i<=NDIM;i++) {
                   10919:       for (j=1;j<=NDIM;j++)
1.226     brouard  10920:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10921:     }
                   10922:     
1.145     brouard  10923:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10924:     /*printf("%lf %lf", p[1], p[2]);*/
                   10925:     
                   10926:     
1.136     brouard  10927: #ifdef GSL
                   10928:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10929: #else
1.126     brouard  10930:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10931: #endif
1.201     brouard  10932:     strcpy(filerespow,"POW-MORT_"); 
                   10933:     strcat(filerespow,fileresu);
1.126     brouard  10934:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10935:       printf("Problem with resultfile: %s\n", filerespow);
                   10936:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10937:     }
1.136     brouard  10938: #ifdef GSL
                   10939:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10940: #else
1.126     brouard  10941:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10942: #endif
1.126     brouard  10943:     /*  for (i=1;i<=nlstate;i++)
                   10944:        for(j=1;j<=nlstate+ndeath;j++)
                   10945:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10946:     */
                   10947:     fprintf(ficrespow,"\n");
1.136     brouard  10948: #ifdef GSL
                   10949:     /* gsl starts here */ 
                   10950:     T = gsl_multimin_fminimizer_nmsimplex;
                   10951:     gsl_multimin_fminimizer *sfm = NULL;
                   10952:     gsl_vector *ss, *x;
                   10953:     gsl_multimin_function minex_func;
                   10954: 
                   10955:     /* Initial vertex size vector */
                   10956:     ss = gsl_vector_alloc (NDIM);
                   10957:     
                   10958:     if (ss == NULL){
                   10959:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10960:     }
                   10961:     /* Set all step sizes to 1 */
                   10962:     gsl_vector_set_all (ss, 0.001);
                   10963: 
                   10964:     /* Starting point */
1.126     brouard  10965:     
1.136     brouard  10966:     x = gsl_vector_alloc (NDIM);
                   10967:     
                   10968:     if (x == NULL){
                   10969:       gsl_vector_free(ss);
                   10970:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10971:     }
                   10972:   
                   10973:     /* Initialize method and iterate */
                   10974:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10975:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10976:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10977:     gsl_vector_set(x, 0, p[1]);
                   10978:     gsl_vector_set(x, 1, p[2]);
                   10979: 
                   10980:     minex_func.f = &gompertz_f;
                   10981:     minex_func.n = NDIM;
                   10982:     minex_func.params = (void *)&p; /* ??? */
                   10983:     
                   10984:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10985:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10986:     
                   10987:     printf("Iterations beginning .....\n\n");
                   10988:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10989: 
                   10990:     iteri=0;
                   10991:     while (rval == GSL_CONTINUE){
                   10992:       iteri++;
                   10993:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10994:       
                   10995:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10996:       fflush(0);
                   10997:       
                   10998:       if (status) 
                   10999:         break;
                   11000:       
                   11001:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11002:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11003:       
                   11004:       if (rval == GSL_SUCCESS)
                   11005:         printf ("converged to a local maximum at\n");
                   11006:       
                   11007:       printf("%5d ", iteri);
                   11008:       for (it = 0; it < NDIM; it++){
                   11009:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11010:       }
                   11011:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11012:     }
                   11013:     
                   11014:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11015:     
                   11016:     gsl_vector_free(x); /* initial values */
                   11017:     gsl_vector_free(ss); /* inital step size */
                   11018:     for (it=0; it<NDIM; it++){
                   11019:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11020:       fprintf(ficrespow," %.12lf", p[it]);
                   11021:     }
                   11022:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11023: #endif
                   11024: #ifdef POWELL
                   11025:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11026: #endif  
1.126     brouard  11027:     fclose(ficrespow);
                   11028:     
1.203     brouard  11029:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11030: 
                   11031:     for(i=1; i <=NDIM; i++)
                   11032:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11033:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11034:     
                   11035:     printf("\nCovariance matrix\n ");
1.203     brouard  11036:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11037:     for(i=1; i <=NDIM; i++) {
                   11038:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11039:                                printf("%f ",matcov[i][j]);
                   11040:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11041:       }
1.203     brouard  11042:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11043:     }
                   11044:     
                   11045:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11046:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11047:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11048:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11049:     }
1.126     brouard  11050:     lsurv=vector(1,AGESUP);
                   11051:     lpop=vector(1,AGESUP);
                   11052:     tpop=vector(1,AGESUP);
                   11053:     lsurv[agegomp]=100000;
                   11054:     
                   11055:     for (k=agegomp;k<=AGESUP;k++) {
                   11056:       agemortsup=k;
                   11057:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11058:     }
                   11059:     
                   11060:     for (k=agegomp;k<agemortsup;k++)
                   11061:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11062:     
                   11063:     for (k=agegomp;k<agemortsup;k++){
                   11064:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11065:       sumlpop=sumlpop+lpop[k];
                   11066:     }
                   11067:     
                   11068:     tpop[agegomp]=sumlpop;
                   11069:     for (k=agegomp;k<(agemortsup-3);k++){
                   11070:       /*  tpop[k+1]=2;*/
                   11071:       tpop[k+1]=tpop[k]-lpop[k];
                   11072:     }
                   11073:     
                   11074:     
                   11075:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11076:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11077:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11078:     
                   11079:     
                   11080:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11081:                ageminpar=50;
                   11082:                agemaxpar=100;
1.194     brouard  11083:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11084:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11085: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11086: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11087:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11088: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11089: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11090:     }else{
                   11091:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11092:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11093:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11094:                }
1.201     brouard  11095:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11096:                     stepm, weightopt,\
                   11097:                     model,imx,p,matcov,agemortsup);
                   11098:     
                   11099:     free_vector(lsurv,1,AGESUP);
                   11100:     free_vector(lpop,1,AGESUP);
                   11101:     free_vector(tpop,1,AGESUP);
1.220     brouard  11102:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11103:     free_ivector(cens,1,n);
                   11104:     free_vector(agecens,1,n);
                   11105:     free_ivector(dcwave,1,n);
1.220     brouard  11106: #ifdef GSL
1.136     brouard  11107: #endif
1.186     brouard  11108:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11109:   /* Standard  */
                   11110:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11111:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11112:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11113:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11114:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11115:     for (k=1; k<=npar;k++)
                   11116:       printf(" %d %8.5f",k,p[k]);
                   11117:     printf("\n");
1.205     brouard  11118:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11119:       /* mlikeli uses func not funcone */
1.247     brouard  11120:       /* for(i=1;i<nlstate;i++){ */
                   11121:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11122:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11123:       /* } */
1.205     brouard  11124:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11125:     }
                   11126:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11127:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11128:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11129:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11130:     }
                   11131:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11132:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11133:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11134:     for (k=1; k<=npar;k++)
                   11135:       printf(" %d %8.5f",k,p[k]);
                   11136:     printf("\n");
                   11137:     
                   11138:     /*--------- results files --------------*/
1.224     brouard  11139:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11140:     
                   11141:     
                   11142:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11143:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11144:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11145:     for(i=1,jk=1; i <=nlstate; i++){
                   11146:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11147:        if (k != i) {
                   11148:          printf("%d%d ",i,k);
                   11149:          fprintf(ficlog,"%d%d ",i,k);
                   11150:          fprintf(ficres,"%1d%1d ",i,k);
                   11151:          for(j=1; j <=ncovmodel; j++){
                   11152:            printf("%12.7f ",p[jk]);
                   11153:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11154:            fprintf(ficres,"%12.7f ",p[jk]);
                   11155:            jk++; 
                   11156:          }
                   11157:          printf("\n");
                   11158:          fprintf(ficlog,"\n");
                   11159:          fprintf(ficres,"\n");
                   11160:        }
1.126     brouard  11161:       }
                   11162:     }
1.203     brouard  11163:     if(mle != 0){
                   11164:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11165:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11166:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11167:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11168:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11169:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11170:        for(k=1; k <=(nlstate+ndeath); k++){
                   11171:          if (k != i) {
                   11172:            printf("%d%d ",i,k);
                   11173:            fprintf(ficlog,"%d%d ",i,k);
                   11174:            for(j=1; j <=ncovmodel; j++){
                   11175:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11176:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11177:              jk++; 
                   11178:            }
                   11179:            printf("\n");
                   11180:            fprintf(ficlog,"\n");
                   11181:          }
                   11182:        }
1.193     brouard  11183:       }
1.203     brouard  11184:     } /* end of hesscov and Wald tests */
1.225     brouard  11185:     
1.203     brouard  11186:     /*  */
1.126     brouard  11187:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11188:     printf("# Scales (for hessian or gradient estimation)\n");
                   11189:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11190:     for(i=1,jk=1; i <=nlstate; i++){
                   11191:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11192:        if (j!=i) {
                   11193:          fprintf(ficres,"%1d%1d",i,j);
                   11194:          printf("%1d%1d",i,j);
                   11195:          fprintf(ficlog,"%1d%1d",i,j);
                   11196:          for(k=1; k<=ncovmodel;k++){
                   11197:            printf(" %.5e",delti[jk]);
                   11198:            fprintf(ficlog," %.5e",delti[jk]);
                   11199:            fprintf(ficres," %.5e",delti[jk]);
                   11200:            jk++;
                   11201:          }
                   11202:          printf("\n");
                   11203:          fprintf(ficlog,"\n");
                   11204:          fprintf(ficres,"\n");
                   11205:        }
1.126     brouard  11206:       }
                   11207:     }
                   11208:     
                   11209:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11210:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11211:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11212:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11213:     /* # 121 Var(a12)\n\ */
                   11214:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11215:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11216:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11217:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11218:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11219:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11220:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11221:     
                   11222:     
                   11223:     /* Just to have a covariance matrix which will be more understandable
                   11224:        even is we still don't want to manage dictionary of variables
                   11225:     */
                   11226:     for(itimes=1;itimes<=2;itimes++){
                   11227:       jj=0;
                   11228:       for(i=1; i <=nlstate; i++){
1.225     brouard  11229:        for(j=1; j <=nlstate+ndeath; j++){
                   11230:          if(j==i) continue;
                   11231:          for(k=1; k<=ncovmodel;k++){
                   11232:            jj++;
                   11233:            ca[0]= k+'a'-1;ca[1]='\0';
                   11234:            if(itimes==1){
                   11235:              if(mle>=1)
                   11236:                printf("#%1d%1d%d",i,j,k);
                   11237:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11238:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11239:            }else{
                   11240:              if(mle>=1)
                   11241:                printf("%1d%1d%d",i,j,k);
                   11242:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11243:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11244:            }
                   11245:            ll=0;
                   11246:            for(li=1;li <=nlstate; li++){
                   11247:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11248:                if(lj==li) continue;
                   11249:                for(lk=1;lk<=ncovmodel;lk++){
                   11250:                  ll++;
                   11251:                  if(ll<=jj){
                   11252:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11253:                    if(ll<jj){
                   11254:                      if(itimes==1){
                   11255:                        if(mle>=1)
                   11256:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11257:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11258:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11259:                      }else{
                   11260:                        if(mle>=1)
                   11261:                          printf(" %.5e",matcov[jj][ll]); 
                   11262:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11263:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11264:                      }
                   11265:                    }else{
                   11266:                      if(itimes==1){
                   11267:                        if(mle>=1)
                   11268:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11269:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11270:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11271:                      }else{
                   11272:                        if(mle>=1)
                   11273:                          printf(" %.7e",matcov[jj][ll]); 
                   11274:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11275:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11276:                      }
                   11277:                    }
                   11278:                  }
                   11279:                } /* end lk */
                   11280:              } /* end lj */
                   11281:            } /* end li */
                   11282:            if(mle>=1)
                   11283:              printf("\n");
                   11284:            fprintf(ficlog,"\n");
                   11285:            fprintf(ficres,"\n");
                   11286:            numlinepar++;
                   11287:          } /* end k*/
                   11288:        } /*end j */
1.126     brouard  11289:       } /* end i */
                   11290:     } /* end itimes */
                   11291:     
                   11292:     fflush(ficlog);
                   11293:     fflush(ficres);
1.225     brouard  11294:     while(fgets(line, MAXLINE, ficpar)) {
                   11295:       /* If line starts with a # it is a comment */
                   11296:       if (line[0] == '#') {
                   11297:        numlinepar++;
                   11298:        fputs(line,stdout);
                   11299:        fputs(line,ficparo);
                   11300:        fputs(line,ficlog);
                   11301:        continue;
                   11302:       }else
                   11303:        break;
                   11304:     }
                   11305:     
1.209     brouard  11306:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11307:     /*   ungetc(c,ficpar); */
                   11308:     /*   fgets(line, MAXLINE, ficpar); */
                   11309:     /*   fputs(line,stdout); */
                   11310:     /*   fputs(line,ficparo); */
                   11311:     /* } */
                   11312:     /* ungetc(c,ficpar); */
1.126     brouard  11313:     
                   11314:     estepm=0;
1.209     brouard  11315:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11316:       
                   11317:       if (num_filled != 6) {
                   11318:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11319:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11320:        goto end;
                   11321:       }
                   11322:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11323:     }
                   11324:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11325:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11326:     
1.209     brouard  11327:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11328:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11329:     if (fage <= 2) {
                   11330:       bage = ageminpar;
                   11331:       fage = agemaxpar;
                   11332:     }
                   11333:     
                   11334:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11335:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11336:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11337:                
1.186     brouard  11338:     /* Other stuffs, more or less useful */    
1.254     brouard  11339:     while(fgets(line, MAXLINE, ficpar)) {
                   11340:       /* If line starts with a # it is a comment */
                   11341:       if (line[0] == '#') {
                   11342:        numlinepar++;
                   11343:        fputs(line,stdout);
                   11344:        fputs(line,ficparo);
                   11345:        fputs(line,ficlog);
                   11346:        continue;
                   11347:       }else
                   11348:        break;
                   11349:     }
                   11350: 
                   11351:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11352:       
                   11353:       if (num_filled != 7) {
                   11354:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11355:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11356:        goto end;
                   11357:       }
                   11358:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11359:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11360:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11361:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11362:     }
1.254     brouard  11363: 
                   11364:     while(fgets(line, MAXLINE, ficpar)) {
                   11365:       /* If line starts with a # it is a comment */
                   11366:       if (line[0] == '#') {
                   11367:        numlinepar++;
                   11368:        fputs(line,stdout);
                   11369:        fputs(line,ficparo);
                   11370:        fputs(line,ficlog);
                   11371:        continue;
                   11372:       }else
                   11373:        break;
1.126     brouard  11374:     }
                   11375:     
                   11376:     
                   11377:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11378:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11379:     
1.254     brouard  11380:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11381:       if (num_filled != 1) {
                   11382:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11383:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11384:        goto end;
                   11385:       }
                   11386:       printf("pop_based=%d\n",popbased);
                   11387:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11388:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11389:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11390:     }
                   11391:      
1.258     brouard  11392:     /* Results */
                   11393:     nresult=0;
                   11394:     do{
                   11395:       if(!fgets(line, MAXLINE, ficpar)){
                   11396:        endishere=1;
                   11397:        parameterline=14;
                   11398:       }else if (line[0] == '#') {
                   11399:        /* If line starts with a # it is a comment */
1.254     brouard  11400:        numlinepar++;
                   11401:        fputs(line,stdout);
                   11402:        fputs(line,ficparo);
                   11403:        fputs(line,ficlog);
                   11404:        continue;
1.258     brouard  11405:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11406:        parameterline=11;
                   11407:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11408:        parameterline=12;
                   11409:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11410:        parameterline=13;
                   11411:       else{
                   11412:        parameterline=14;
1.254     brouard  11413:       }
1.258     brouard  11414:       switch (parameterline){ 
                   11415:       case 11:
                   11416:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11417:          if (num_filled != 8) {
                   11418:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11419:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11420:            goto end;
                   11421:          }
                   11422:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11423:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11424:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11425:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11426:          /* day and month of proj2 are not used but only year anproj2.*/
                   11427:        }
1.254     brouard  11428:        break;
1.258     brouard  11429:       case 12:
                   11430:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11431:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11432:          if (num_filled != 8) {
1.262     brouard  11433:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11434:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  11435:            goto end;
                   11436:          }
                   11437:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11438:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11439:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11440:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11441:          /* day and month of proj2 are not used but only year anproj2.*/
                   11442:        }
1.230     brouard  11443:        break;
1.258     brouard  11444:       case 13:
                   11445:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11446:          if (num_filled == 0){
                   11447:            resultline[0]='\0';
                   11448:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11449:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11450:            break;
                   11451:          } else if (num_filled != 1){
                   11452:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11453:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11454:          }
                   11455:          nresult++; /* Sum of resultlines */
                   11456:          printf("Result %d: result=%s\n",nresult, resultline);
                   11457:          if(nresult > MAXRESULTLINES){
                   11458:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11459:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11460:            goto end;
                   11461:          }
                   11462:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11463:          fprintf(ficparo,"result: %s\n",resultline);
                   11464:          fprintf(ficres,"result: %s\n",resultline);
                   11465:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11466:          break;
1.258     brouard  11467:        case 14: 
1.259     brouard  11468:          if(ncovmodel >2 && nresult==0 ){
                   11469:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11470:            goto end;
                   11471:          }
1.259     brouard  11472:          break;
1.258     brouard  11473:        default:
                   11474:          nresult=1;
                   11475:          decoderesult(".",nresult ); /* No covariate */
                   11476:        }
                   11477:       } /* End switch parameterline */
                   11478:     }while(endishere==0); /* End do */
1.126     brouard  11479:     
1.230     brouard  11480:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11481:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11482:     
                   11483:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11484:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11485:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11486: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11487: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11488:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11489: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11490: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11491:     }else{
1.218     brouard  11492:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11493:     }
                   11494:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11495:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11496:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11497:                
1.225     brouard  11498:     /*------------ free_vector  -------------*/
                   11499:     /*  chdir(path); */
1.220     brouard  11500:                
1.215     brouard  11501:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11502:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11503:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11504:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11505:     free_lvector(num,1,n);
                   11506:     free_vector(agedc,1,n);
                   11507:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11508:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11509:     fclose(ficparo);
                   11510:     fclose(ficres);
1.220     brouard  11511:                
                   11512:                
1.186     brouard  11513:     /* Other results (useful)*/
1.220     brouard  11514:                
                   11515:                
1.126     brouard  11516:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11517:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11518:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11519:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11520:     fclose(ficrespl);
                   11521: 
                   11522:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11523:     /*#include "hpijx.h"*/
                   11524:     hPijx(p, bage, fage);
1.145     brouard  11525:     fclose(ficrespij);
1.227     brouard  11526:     
1.220     brouard  11527:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11528:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11529:     k=1;
1.126     brouard  11530:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11531:     
1.219     brouard  11532:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11533:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11534:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11535:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11536:        for(k=1;k<=ncovcombmax;k++)
                   11537:          probs[i][j][k]=0.;
1.219     brouard  11538:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11539:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11540:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11541:       for(i=1;i<=AGESUP;i++)
                   11542:        for(j=1;j<=nlstate;j++)
                   11543:          for(k=1;k<=ncovcombmax;k++)
                   11544:            mobaverages[i][j][k]=0.;
1.219     brouard  11545:       mobaverage=mobaverages;
                   11546:       if (mobilav!=0) {
1.235     brouard  11547:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11548:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11549:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11550:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11551:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11552:        }
1.219     brouard  11553:       }
                   11554:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11555:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11556:       else if (mobilavproj !=0) {
1.235     brouard  11557:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11558:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11559:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11560:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11561:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11562:        }
1.219     brouard  11563:       }
                   11564:     }/* end if moving average */
1.227     brouard  11565:     
1.126     brouard  11566:     /*---------- Forecasting ------------------*/
                   11567:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11568:     if(prevfcast==1){
                   11569:       /*    if(stepm ==1){*/
1.225     brouard  11570:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11571:     }
1.217     brouard  11572:     if(backcast==1){
1.219     brouard  11573:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11574:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11575:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11576: 
                   11577:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11578: 
                   11579:       bprlim=matrix(1,nlstate,1,nlstate);
                   11580:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11581:       fclose(ficresplb);
                   11582: 
1.222     brouard  11583:       hBijx(p, bage, fage, mobaverage);
                   11584:       fclose(ficrespijb);
1.219     brouard  11585:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11586: 
                   11587:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11588:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11589:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11590:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11591:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11592:     }
1.217     brouard  11593:     
1.186     brouard  11594:  
                   11595:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11596: 
1.215     brouard  11597:     free_ivector(wav,1,imx);
                   11598:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11599:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11600:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11601:                
                   11602:                
1.127     brouard  11603:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11604:                
1.201     brouard  11605:     strcpy(filerese,"E_");
                   11606:     strcat(filerese,fileresu);
1.126     brouard  11607:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11608:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11609:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11610:     }
1.208     brouard  11611:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11612:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11613: 
                   11614:     pstamp(ficreseij);
1.219     brouard  11615:                
1.235     brouard  11616:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11617:     if (cptcovn < 1){i1=1;}
                   11618:     
                   11619:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11620:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11621:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11622:        continue;
1.219     brouard  11623:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11624:       printf("\n#****** ");
1.225     brouard  11625:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11626:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11627:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11628:       }
                   11629:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11630:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11631:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11632:       }
                   11633:       fprintf(ficreseij,"******\n");
1.235     brouard  11634:       printf("******\n");
1.219     brouard  11635:       
                   11636:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11637:       oldm=oldms;savm=savms;
1.235     brouard  11638:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11639:       
1.219     brouard  11640:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11641:     }
                   11642:     fclose(ficreseij);
1.208     brouard  11643:     printf("done evsij\n");fflush(stdout);
                   11644:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11645:                
1.227     brouard  11646:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11647:                
                   11648:                
1.201     brouard  11649:     strcpy(filerest,"T_");
                   11650:     strcat(filerest,fileresu);
1.127     brouard  11651:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11652:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11653:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11654:     }
1.208     brouard  11655:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11656:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11657:                
1.126     brouard  11658: 
1.201     brouard  11659:     strcpy(fileresstde,"STDE_");
                   11660:     strcat(fileresstde,fileresu);
1.126     brouard  11661:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11662:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11663:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11664:     }
1.227     brouard  11665:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11666:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11667: 
1.201     brouard  11668:     strcpy(filerescve,"CVE_");
                   11669:     strcat(filerescve,fileresu);
1.126     brouard  11670:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11671:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11672:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11673:     }
1.227     brouard  11674:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11675:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11676: 
1.201     brouard  11677:     strcpy(fileresv,"V_");
                   11678:     strcat(fileresv,fileresu);
1.126     brouard  11679:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11680:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11681:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11682:     }
1.227     brouard  11683:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11684:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11685: 
1.145     brouard  11686:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11687:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11688:           
1.235     brouard  11689:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11690:     if (cptcovn < 1){i1=1;}
                   11691:     
                   11692:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11693:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11694:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11695:        continue;
1.242     brouard  11696:       printf("\n#****** Result for:");
                   11697:       fprintf(ficrest,"\n#****** Result for:");
                   11698:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11699:       for(j=1;j<=cptcoveff;j++){ 
                   11700:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11701:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11702:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11703:       }
1.235     brouard  11704:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11705:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11706:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11707:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11708:       }        
1.208     brouard  11709:       fprintf(ficrest,"******\n");
1.227     brouard  11710:       fprintf(ficlog,"******\n");
                   11711:       printf("******\n");
1.208     brouard  11712:       
                   11713:       fprintf(ficresstdeij,"\n#****** ");
                   11714:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11715:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11716:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11717:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11718:       }
1.235     brouard  11719:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11720:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11721:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11722:       }        
1.208     brouard  11723:       fprintf(ficresstdeij,"******\n");
                   11724:       fprintf(ficrescveij,"******\n");
                   11725:       
                   11726:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11727:       /* pstamp(ficresvij); */
1.225     brouard  11728:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11729:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11730:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11731:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11732:       }        
1.208     brouard  11733:       fprintf(ficresvij,"******\n");
                   11734:       
                   11735:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11736:       oldm=oldms;savm=savms;
1.235     brouard  11737:       printf(" cvevsij ");
                   11738:       fprintf(ficlog, " cvevsij ");
                   11739:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11740:       printf(" end cvevsij \n ");
                   11741:       fprintf(ficlog, " end cvevsij \n ");
                   11742:       
                   11743:       /*
                   11744:        */
                   11745:       /* goto endfree; */
                   11746:       
                   11747:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11748:       pstamp(ficrest);
                   11749:       
                   11750:       
                   11751:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11752:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11753:        cptcod= 0; /* To be deleted */
                   11754:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11755:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11756:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11757:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11758:        if(vpopbased==1)
                   11759:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11760:        else
                   11761:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11762:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11763:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11764:        fprintf(ficrest,"\n");
                   11765:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11766:        epj=vector(1,nlstate+1);
                   11767:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11768:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11769:        for(age=bage; age <=fage ;age++){
1.235     brouard  11770:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11771:          if (vpopbased==1) {
                   11772:            if(mobilav ==0){
                   11773:              for(i=1; i<=nlstate;i++)
                   11774:                prlim[i][i]=probs[(int)age][i][k];
                   11775:            }else{ /* mobilav */ 
                   11776:              for(i=1; i<=nlstate;i++)
                   11777:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11778:            }
                   11779:          }
1.219     brouard  11780:          
1.227     brouard  11781:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11782:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11783:          /* printf(" age %4.0f ",age); */
                   11784:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11785:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11786:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11787:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11788:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11789:            }
                   11790:            epj[nlstate+1] +=epj[j];
                   11791:          }
                   11792:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11793:          
1.227     brouard  11794:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11795:            for(j=1;j <=nlstate;j++)
                   11796:              vepp += vareij[i][j][(int)age];
                   11797:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11798:          for(j=1;j <=nlstate;j++){
                   11799:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11800:          }
                   11801:          fprintf(ficrest,"\n");
                   11802:        }
1.208     brouard  11803:       } /* End vpopbased */
                   11804:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11805:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11806:       free_vector(epj,1,nlstate+1);
1.235     brouard  11807:       printf("done selection\n");fflush(stdout);
                   11808:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11809:       
1.145     brouard  11810:       /*}*/
1.235     brouard  11811:     } /* End k selection */
1.227     brouard  11812: 
                   11813:     printf("done State-specific expectancies\n");fflush(stdout);
                   11814:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11815: 
1.126     brouard  11816:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11817:     
1.201     brouard  11818:     strcpy(fileresvpl,"VPL_");
                   11819:     strcat(fileresvpl,fileresu);
1.126     brouard  11820:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11821:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11822:       exit(0);
                   11823:     }
1.208     brouard  11824:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11825:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11826:     
1.145     brouard  11827:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11828:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11829:     
1.235     brouard  11830:     i1=pow(2,cptcoveff);
                   11831:     if (cptcovn < 1){i1=1;}
                   11832: 
                   11833:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11834:     for(k=1; k<=i1;k++){
1.253     brouard  11835:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11836:        continue;
1.227     brouard  11837:       fprintf(ficresvpl,"\n#****** ");
                   11838:       printf("\n#****** ");
                   11839:       fprintf(ficlog,"\n#****** ");
                   11840:       for(j=1;j<=cptcoveff;j++) {
                   11841:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11842:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11843:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11844:       }
1.235     brouard  11845:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11846:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11847:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11848:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11849:       }        
1.227     brouard  11850:       fprintf(ficresvpl,"******\n");
                   11851:       printf("******\n");
                   11852:       fprintf(ficlog,"******\n");
                   11853:       
                   11854:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11855:       oldm=oldms;savm=savms;
1.235     brouard  11856:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11857:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11858:       /*}*/
1.126     brouard  11859:     }
1.227     brouard  11860:     
1.126     brouard  11861:     fclose(ficresvpl);
1.208     brouard  11862:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11863:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11864:     
                   11865:     free_vector(weight,1,n);
                   11866:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11867:     free_imatrix(s,1,maxwav+1,1,n);
                   11868:     free_matrix(anint,1,maxwav,1,n); 
                   11869:     free_matrix(mint,1,maxwav,1,n);
                   11870:     free_ivector(cod,1,n);
                   11871:     free_ivector(tab,1,NCOVMAX);
                   11872:     fclose(ficresstdeij);
                   11873:     fclose(ficrescveij);
                   11874:     fclose(ficresvij);
                   11875:     fclose(ficrest);
                   11876:     fclose(ficpar);
                   11877:     
                   11878:     
1.126     brouard  11879:     /*---------- End : free ----------------*/
1.219     brouard  11880:     if (mobilav!=0 ||mobilavproj !=0)
                   11881:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11882:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11883:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11884:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11885:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11886:   /* endfree:*/
                   11887:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11888:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11889:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11890:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11891:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11892:   free_matrix(coqvar,1,maxwav,1,n);
                   11893:   free_matrix(covar,0,NCOVMAX,1,n);
                   11894:   free_matrix(matcov,1,npar,1,npar);
                   11895:   free_matrix(hess,1,npar,1,npar);
                   11896:   /*free_vector(delti,1,npar);*/
                   11897:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11898:   free_matrix(agev,1,maxwav,1,imx);
                   11899:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11900:   
                   11901:   free_ivector(ncodemax,1,NCOVMAX);
                   11902:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11903:   free_ivector(Dummy,-1,NCOVMAX);
                   11904:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11905:   free_ivector(DummyV,1,NCOVMAX);
                   11906:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11907:   free_ivector(Typevar,-1,NCOVMAX);
                   11908:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11909:   free_ivector(TvarsQ,1,NCOVMAX);
                   11910:   free_ivector(TvarsQind,1,NCOVMAX);
                   11911:   free_ivector(TvarsD,1,NCOVMAX);
                   11912:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11913:   free_ivector(TvarFD,1,NCOVMAX);
                   11914:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11915:   free_ivector(TvarF,1,NCOVMAX);
                   11916:   free_ivector(TvarFind,1,NCOVMAX);
                   11917:   free_ivector(TvarV,1,NCOVMAX);
                   11918:   free_ivector(TvarVind,1,NCOVMAX);
                   11919:   free_ivector(TvarA,1,NCOVMAX);
                   11920:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11921:   free_ivector(TvarFQ,1,NCOVMAX);
                   11922:   free_ivector(TvarFQind,1,NCOVMAX);
                   11923:   free_ivector(TvarVD,1,NCOVMAX);
                   11924:   free_ivector(TvarVDind,1,NCOVMAX);
                   11925:   free_ivector(TvarVQ,1,NCOVMAX);
                   11926:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11927:   free_ivector(Tvarsel,1,NCOVMAX);
                   11928:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11929:   free_ivector(Tposprod,1,NCOVMAX);
                   11930:   free_ivector(Tprod,1,NCOVMAX);
                   11931:   free_ivector(Tvaraff,1,NCOVMAX);
                   11932:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11933:   free_ivector(Tage,1,NCOVMAX);
                   11934:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11935:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11936:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11937:   
                   11938:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11939:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11940:   fflush(fichtm);
                   11941:   fflush(ficgp);
                   11942:   
1.227     brouard  11943:   
1.126     brouard  11944:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11945:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11946:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11947:   }else{
                   11948:     printf("End of Imach\n");
                   11949:     fprintf(ficlog,"End of Imach\n");
                   11950:   }
                   11951:   printf("See log file on %s\n",filelog);
                   11952:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11953:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11954:   rend_time = time(NULL);  
                   11955:   end_time = *localtime(&rend_time);
                   11956:   /* tml = *localtime(&end_time.tm_sec); */
                   11957:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11958:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11959:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11960:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11961:   
1.157     brouard  11962:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11963:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11964:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11965:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11966: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11967:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11968:   fclose(fichtm);
                   11969:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11970:   fclose(fichtmcov);
                   11971:   fclose(ficgp);
                   11972:   fclose(ficlog);
                   11973:   /*------ End -----------*/
1.227     brouard  11974:   
                   11975:   
                   11976:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11977: #ifdef WIN32
1.227     brouard  11978:   if (_chdir(pathcd) != 0)
                   11979:     printf("Can't move to directory %s!\n",path);
                   11980:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11981: #else
1.227     brouard  11982:     if(chdir(pathcd) != 0)
                   11983:       printf("Can't move to directory %s!\n", path);
                   11984:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11985: #endif 
1.126     brouard  11986:     printf("Current directory %s!\n",pathcd);
                   11987:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11988:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11989: #ifdef _WIN32
1.126     brouard  11990:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11991: #endif
                   11992:   if(!stat(plotcmd,&info)){
1.158     brouard  11993:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11994:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11995:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11996:     }else
                   11997:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11998: #ifdef __unix
1.126     brouard  11999:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12000:     if(!stat(plotcmd,&info)){
1.158     brouard  12001:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12002:     }else
                   12003:       strcpy(pplotcmd,plotcmd);
                   12004: #endif
                   12005:   }else
                   12006:     strcpy(pplotcmd,plotcmd);
                   12007:   
                   12008:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12009:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12010:   
1.126     brouard  12011:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12012:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12013:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12014:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12015:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12016:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12017:   }
1.158     brouard  12018:   printf(" Successful, please wait...");
1.126     brouard  12019:   while (z[0] != 'q') {
                   12020:     /* chdir(path); */
1.154     brouard  12021:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12022:     scanf("%s",z);
                   12023: /*     if (z[0] == 'c') system("./imach"); */
                   12024:     if (z[0] == 'e') {
1.158     brouard  12025: #ifdef __APPLE__
1.152     brouard  12026:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12027: #elif __linux
                   12028:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12029: #else
1.152     brouard  12030:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12031: #endif
                   12032:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12033:       system(pplotcmd);
1.126     brouard  12034:     }
                   12035:     else if (z[0] == 'g') system(plotcmd);
                   12036:     else if (z[0] == 'q') exit(0);
                   12037:   }
1.227     brouard  12038: end:
1.126     brouard  12039:   while (z[0] != 'q') {
1.195     brouard  12040:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12041:     scanf("%s",z);
                   12042:   }
                   12043: }

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