Annotation of imach/src/imach.c, revision 1.270

1.270   ! brouard     1: /* $Id: imach.c,v 1.269 2017/05/23 08:39:25 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.270   ! brouard     4:   Revision 1.269  2017/05/23 08:39:25  brouard
        !             5:   Summary: Code into subroutine, cleanings
        !             6: 
1.269     brouard     7:   Revision 1.268  2017/05/18 20:09:32  brouard
                      8:   Summary: backprojection and confidence intervals of backprevalence
                      9: 
1.268     brouard    10:   Revision 1.267  2017/05/13 10:25:05  brouard
                     11:   Summary: temporary save for backprojection
                     12: 
1.267     brouard    13:   Revision 1.266  2017/05/13 07:26:12  brouard
                     14:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     15: 
1.266     brouard    16:   Revision 1.265  2017/04/26 16:22:11  brouard
                     17:   Summary: imach 0.99r13 Some bugs fixed
                     18: 
1.265     brouard    19:   Revision 1.264  2017/04/26 06:01:29  brouard
                     20:   Summary: Labels in graphs
                     21: 
1.264     brouard    22:   Revision 1.263  2017/04/24 15:23:15  brouard
                     23:   Summary: to save
                     24: 
1.263     brouard    25:   Revision 1.262  2017/04/18 16:48:12  brouard
                     26:   *** empty log message ***
                     27: 
1.262     brouard    28:   Revision 1.261  2017/04/05 10:14:09  brouard
                     29:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     30: 
1.261     brouard    31:   Revision 1.260  2017/04/04 17:46:59  brouard
                     32:   Summary: Gnuplot indexations fixed (humm)
                     33: 
1.260     brouard    34:   Revision 1.259  2017/04/04 13:01:16  brouard
                     35:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     36: 
1.259     brouard    37:   Revision 1.258  2017/04/03 10:17:47  brouard
                     38:   Summary: Version 0.99r12
                     39: 
                     40:   Some cleanings, conformed with updated documentation.
                     41: 
1.258     brouard    42:   Revision 1.257  2017/03/29 16:53:30  brouard
                     43:   Summary: Temp
                     44: 
1.257     brouard    45:   Revision 1.256  2017/03/27 05:50:23  brouard
                     46:   Summary: Temporary
                     47: 
1.256     brouard    48:   Revision 1.255  2017/03/08 16:02:28  brouard
                     49:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     50: 
1.255     brouard    51:   Revision 1.254  2017/03/08 07:13:00  brouard
                     52:   Summary: Fixing data parameter line
                     53: 
1.254     brouard    54:   Revision 1.253  2016/12/15 11:59:41  brouard
                     55:   Summary: 0.99 in progress
                     56: 
1.253     brouard    57:   Revision 1.252  2016/09/15 21:15:37  brouard
                     58:   *** empty log message ***
                     59: 
1.252     brouard    60:   Revision 1.251  2016/09/15 15:01:13  brouard
                     61:   Summary: not working
                     62: 
1.251     brouard    63:   Revision 1.250  2016/09/08 16:07:27  brouard
                     64:   Summary: continue
                     65: 
1.250     brouard    66:   Revision 1.249  2016/09/07 17:14:18  brouard
                     67:   Summary: Starting values from frequencies
                     68: 
1.249     brouard    69:   Revision 1.248  2016/09/07 14:10:18  brouard
                     70:   *** empty log message ***
                     71: 
1.248     brouard    72:   Revision 1.247  2016/09/02 11:11:21  brouard
                     73:   *** empty log message ***
                     74: 
1.247     brouard    75:   Revision 1.246  2016/09/02 08:49:22  brouard
                     76:   *** empty log message ***
                     77: 
1.246     brouard    78:   Revision 1.245  2016/09/02 07:25:01  brouard
                     79:   *** empty log message ***
                     80: 
1.245     brouard    81:   Revision 1.244  2016/09/02 07:17:34  brouard
                     82:   *** empty log message ***
                     83: 
1.244     brouard    84:   Revision 1.243  2016/09/02 06:45:35  brouard
                     85:   *** empty log message ***
                     86: 
1.243     brouard    87:   Revision 1.242  2016/08/30 15:01:20  brouard
                     88:   Summary: Fixing a lots
                     89: 
1.242     brouard    90:   Revision 1.241  2016/08/29 17:17:25  brouard
                     91:   Summary: gnuplot problem in Back projection to fix
                     92: 
1.241     brouard    93:   Revision 1.240  2016/08/29 07:53:18  brouard
                     94:   Summary: Better
                     95: 
1.240     brouard    96:   Revision 1.239  2016/08/26 15:51:03  brouard
                     97:   Summary: Improvement in Powell output in order to copy and paste
                     98: 
                     99:   Author:
                    100: 
1.239     brouard   101:   Revision 1.238  2016/08/26 14:23:35  brouard
                    102:   Summary: Starting tests of 0.99
                    103: 
1.238     brouard   104:   Revision 1.237  2016/08/26 09:20:19  brouard
                    105:   Summary: to valgrind
                    106: 
1.237     brouard   107:   Revision 1.236  2016/08/25 10:50:18  brouard
                    108:   *** empty log message ***
                    109: 
1.236     brouard   110:   Revision 1.235  2016/08/25 06:59:23  brouard
                    111:   *** empty log message ***
                    112: 
1.235     brouard   113:   Revision 1.234  2016/08/23 16:51:20  brouard
                    114:   *** empty log message ***
                    115: 
1.234     brouard   116:   Revision 1.233  2016/08/23 07:40:50  brouard
                    117:   Summary: not working
                    118: 
1.233     brouard   119:   Revision 1.232  2016/08/22 14:20:21  brouard
                    120:   Summary: not working
                    121: 
1.232     brouard   122:   Revision 1.231  2016/08/22 07:17:15  brouard
                    123:   Summary: not working
                    124: 
1.231     brouard   125:   Revision 1.230  2016/08/22 06:55:53  brouard
                    126:   Summary: Not working
                    127: 
1.230     brouard   128:   Revision 1.229  2016/07/23 09:45:53  brouard
                    129:   Summary: Completing for func too
                    130: 
1.229     brouard   131:   Revision 1.228  2016/07/22 17:45:30  brouard
                    132:   Summary: Fixing some arrays, still debugging
                    133: 
1.227     brouard   134:   Revision 1.226  2016/07/12 18:42:34  brouard
                    135:   Summary: temp
                    136: 
1.226     brouard   137:   Revision 1.225  2016/07/12 08:40:03  brouard
                    138:   Summary: saving but not running
                    139: 
1.225     brouard   140:   Revision 1.224  2016/07/01 13:16:01  brouard
                    141:   Summary: Fixes
                    142: 
1.224     brouard   143:   Revision 1.223  2016/02/19 09:23:35  brouard
                    144:   Summary: temporary
                    145: 
1.223     brouard   146:   Revision 1.222  2016/02/17 08:14:50  brouard
                    147:   Summary: Probably last 0.98 stable version 0.98r6
                    148: 
1.222     brouard   149:   Revision 1.221  2016/02/15 23:35:36  brouard
                    150:   Summary: minor bug
                    151: 
1.220     brouard   152:   Revision 1.219  2016/02/15 00:48:12  brouard
                    153:   *** empty log message ***
                    154: 
1.219     brouard   155:   Revision 1.218  2016/02/12 11:29:23  brouard
                    156:   Summary: 0.99 Back projections
                    157: 
1.218     brouard   158:   Revision 1.217  2015/12/23 17:18:31  brouard
                    159:   Summary: Experimental backcast
                    160: 
1.217     brouard   161:   Revision 1.216  2015/12/18 17:32:11  brouard
                    162:   Summary: 0.98r4 Warning and status=-2
                    163: 
                    164:   Version 0.98r4 is now:
                    165:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    166:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    167:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    168: 
1.216     brouard   169:   Revision 1.215  2015/12/16 08:52:24  brouard
                    170:   Summary: 0.98r4 working
                    171: 
1.215     brouard   172:   Revision 1.214  2015/12/16 06:57:54  brouard
                    173:   Summary: temporary not working
                    174: 
1.214     brouard   175:   Revision 1.213  2015/12/11 18:22:17  brouard
                    176:   Summary: 0.98r4
                    177: 
1.213     brouard   178:   Revision 1.212  2015/11/21 12:47:24  brouard
                    179:   Summary: minor typo
                    180: 
1.212     brouard   181:   Revision 1.211  2015/11/21 12:41:11  brouard
                    182:   Summary: 0.98r3 with some graph of projected cross-sectional
                    183: 
                    184:   Author: Nicolas Brouard
                    185: 
1.211     brouard   186:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   187:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   188:   Summary: Adding ftolpl parameter
                    189:   Author: N Brouard
                    190: 
                    191:   We had difficulties to get smoothed confidence intervals. It was due
                    192:   to the period prevalence which wasn't computed accurately. The inner
                    193:   parameter ftolpl is now an outer parameter of the .imach parameter
                    194:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    195:   computation are long.
                    196: 
1.209     brouard   197:   Revision 1.208  2015/11/17 14:31:57  brouard
                    198:   Summary: temporary
                    199: 
1.208     brouard   200:   Revision 1.207  2015/10/27 17:36:57  brouard
                    201:   *** empty log message ***
                    202: 
1.207     brouard   203:   Revision 1.206  2015/10/24 07:14:11  brouard
                    204:   *** empty log message ***
                    205: 
1.206     brouard   206:   Revision 1.205  2015/10/23 15:50:53  brouard
                    207:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    208: 
1.205     brouard   209:   Revision 1.204  2015/10/01 16:20:26  brouard
                    210:   Summary: Some new graphs of contribution to likelihood
                    211: 
1.204     brouard   212:   Revision 1.203  2015/09/30 17:45:14  brouard
                    213:   Summary: looking at better estimation of the hessian
                    214: 
                    215:   Also a better criteria for convergence to the period prevalence And
                    216:   therefore adding the number of years needed to converge. (The
                    217:   prevalence in any alive state shold sum to one
                    218: 
1.203     brouard   219:   Revision 1.202  2015/09/22 19:45:16  brouard
                    220:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    221: 
1.202     brouard   222:   Revision 1.201  2015/09/15 17:34:58  brouard
                    223:   Summary: 0.98r0
                    224: 
                    225:   - Some new graphs like suvival functions
                    226:   - Some bugs fixed like model=1+age+V2.
                    227: 
1.201     brouard   228:   Revision 1.200  2015/09/09 16:53:55  brouard
                    229:   Summary: Big bug thanks to Flavia
                    230: 
                    231:   Even model=1+age+V2. did not work anymore
                    232: 
1.200     brouard   233:   Revision 1.199  2015/09/07 14:09:23  brouard
                    234:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    235: 
1.199     brouard   236:   Revision 1.198  2015/09/03 07:14:39  brouard
                    237:   Summary: 0.98q5 Flavia
                    238: 
1.198     brouard   239:   Revision 1.197  2015/09/01 18:24:39  brouard
                    240:   *** empty log message ***
                    241: 
1.197     brouard   242:   Revision 1.196  2015/08/18 23:17:52  brouard
                    243:   Summary: 0.98q5
                    244: 
1.196     brouard   245:   Revision 1.195  2015/08/18 16:28:39  brouard
                    246:   Summary: Adding a hack for testing purpose
                    247: 
                    248:   After reading the title, ftol and model lines, if the comment line has
                    249:   a q, starting with #q, the answer at the end of the run is quit. It
                    250:   permits to run test files in batch with ctest. The former workaround was
                    251:   $ echo q | imach foo.imach
                    252: 
1.195     brouard   253:   Revision 1.194  2015/08/18 13:32:00  brouard
                    254:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    255: 
1.194     brouard   256:   Revision 1.193  2015/08/04 07:17:42  brouard
                    257:   Summary: 0.98q4
                    258: 
1.193     brouard   259:   Revision 1.192  2015/07/16 16:49:02  brouard
                    260:   Summary: Fixing some outputs
                    261: 
1.192     brouard   262:   Revision 1.191  2015/07/14 10:00:33  brouard
                    263:   Summary: Some fixes
                    264: 
1.191     brouard   265:   Revision 1.190  2015/05/05 08:51:13  brouard
                    266:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    267: 
                    268:   Fix 1+age+.
                    269: 
1.190     brouard   270:   Revision 1.189  2015/04/30 14:45:16  brouard
                    271:   Summary: 0.98q2
                    272: 
1.189     brouard   273:   Revision 1.188  2015/04/30 08:27:53  brouard
                    274:   *** empty log message ***
                    275: 
1.188     brouard   276:   Revision 1.187  2015/04/29 09:11:15  brouard
                    277:   *** empty log message ***
                    278: 
1.187     brouard   279:   Revision 1.186  2015/04/23 12:01:52  brouard
                    280:   Summary: V1*age is working now, version 0.98q1
                    281: 
                    282:   Some codes had been disabled in order to simplify and Vn*age was
                    283:   working in the optimization phase, ie, giving correct MLE parameters,
                    284:   but, as usual, outputs were not correct and program core dumped.
                    285: 
1.186     brouard   286:   Revision 1.185  2015/03/11 13:26:42  brouard
                    287:   Summary: Inclusion of compile and links command line for Intel Compiler
                    288: 
1.185     brouard   289:   Revision 1.184  2015/03/11 11:52:39  brouard
                    290:   Summary: Back from Windows 8. Intel Compiler
                    291: 
1.184     brouard   292:   Revision 1.183  2015/03/10 20:34:32  brouard
                    293:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    294: 
                    295:   We use directest instead of original Powell test; probably no
                    296:   incidence on the results, but better justifications;
                    297:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    298:   wrong results.
                    299: 
1.183     brouard   300:   Revision 1.182  2015/02/12 08:19:57  brouard
                    301:   Summary: Trying to keep directest which seems simpler and more general
                    302:   Author: Nicolas Brouard
                    303: 
1.182     brouard   304:   Revision 1.181  2015/02/11 23:22:24  brouard
                    305:   Summary: Comments on Powell added
                    306: 
                    307:   Author:
                    308: 
1.181     brouard   309:   Revision 1.180  2015/02/11 17:33:45  brouard
                    310:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    311: 
1.180     brouard   312:   Revision 1.179  2015/01/04 09:57:06  brouard
                    313:   Summary: back to OS/X
                    314: 
1.179     brouard   315:   Revision 1.178  2015/01/04 09:35:48  brouard
                    316:   *** empty log message ***
                    317: 
1.178     brouard   318:   Revision 1.177  2015/01/03 18:40:56  brouard
                    319:   Summary: Still testing ilc32 on OSX
                    320: 
1.177     brouard   321:   Revision 1.176  2015/01/03 16:45:04  brouard
                    322:   *** empty log message ***
                    323: 
1.176     brouard   324:   Revision 1.175  2015/01/03 16:33:42  brouard
                    325:   *** empty log message ***
                    326: 
1.175     brouard   327:   Revision 1.174  2015/01/03 16:15:49  brouard
                    328:   Summary: Still in cross-compilation
                    329: 
1.174     brouard   330:   Revision 1.173  2015/01/03 12:06:26  brouard
                    331:   Summary: trying to detect cross-compilation
                    332: 
1.173     brouard   333:   Revision 1.172  2014/12/27 12:07:47  brouard
                    334:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    335: 
1.172     brouard   336:   Revision 1.171  2014/12/23 13:26:59  brouard
                    337:   Summary: Back from Visual C
                    338: 
                    339:   Still problem with utsname.h on Windows
                    340: 
1.171     brouard   341:   Revision 1.170  2014/12/23 11:17:12  brouard
                    342:   Summary: Cleaning some \%% back to %%
                    343: 
                    344:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    345: 
1.170     brouard   346:   Revision 1.169  2014/12/22 23:08:31  brouard
                    347:   Summary: 0.98p
                    348: 
                    349:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    350: 
1.169     brouard   351:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   352:   Summary: update
1.169     brouard   353: 
1.168     brouard   354:   Revision 1.167  2014/12/22 13:50:56  brouard
                    355:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    356: 
                    357:   Testing on Linux 64
                    358: 
1.167     brouard   359:   Revision 1.166  2014/12/22 11:40:47  brouard
                    360:   *** empty log message ***
                    361: 
1.166     brouard   362:   Revision 1.165  2014/12/16 11:20:36  brouard
                    363:   Summary: After compiling on Visual C
                    364: 
                    365:   * imach.c (Module): Merging 1.61 to 1.162
                    366: 
1.165     brouard   367:   Revision 1.164  2014/12/16 10:52:11  brouard
                    368:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    369: 
                    370:   * imach.c (Module): Merging 1.61 to 1.162
                    371: 
1.164     brouard   372:   Revision 1.163  2014/12/16 10:30:11  brouard
                    373:   * imach.c (Module): Merging 1.61 to 1.162
                    374: 
1.163     brouard   375:   Revision 1.162  2014/09/25 11:43:39  brouard
                    376:   Summary: temporary backup 0.99!
                    377: 
1.162     brouard   378:   Revision 1.1  2014/09/16 11:06:58  brouard
                    379:   Summary: With some code (wrong) for nlopt
                    380: 
                    381:   Author:
                    382: 
                    383:   Revision 1.161  2014/09/15 20:41:41  brouard
                    384:   Summary: Problem with macro SQR on Intel compiler
                    385: 
1.161     brouard   386:   Revision 1.160  2014/09/02 09:24:05  brouard
                    387:   *** empty log message ***
                    388: 
1.160     brouard   389:   Revision 1.159  2014/09/01 10:34:10  brouard
                    390:   Summary: WIN32
                    391:   Author: Brouard
                    392: 
1.159     brouard   393:   Revision 1.158  2014/08/27 17:11:51  brouard
                    394:   *** empty log message ***
                    395: 
1.158     brouard   396:   Revision 1.157  2014/08/27 16:26:55  brouard
                    397:   Summary: Preparing windows Visual studio version
                    398:   Author: Brouard
                    399: 
                    400:   In order to compile on Visual studio, time.h is now correct and time_t
                    401:   and tm struct should be used. difftime should be used but sometimes I
                    402:   just make the differences in raw time format (time(&now).
                    403:   Trying to suppress #ifdef LINUX
                    404:   Add xdg-open for __linux in order to open default browser.
                    405: 
1.157     brouard   406:   Revision 1.156  2014/08/25 20:10:10  brouard
                    407:   *** empty log message ***
                    408: 
1.156     brouard   409:   Revision 1.155  2014/08/25 18:32:34  brouard
                    410:   Summary: New compile, minor changes
                    411:   Author: Brouard
                    412: 
1.155     brouard   413:   Revision 1.154  2014/06/20 17:32:08  brouard
                    414:   Summary: Outputs now all graphs of convergence to period prevalence
                    415: 
1.154     brouard   416:   Revision 1.153  2014/06/20 16:45:46  brouard
                    417:   Summary: If 3 live state, convergence to period prevalence on same graph
                    418:   Author: Brouard
                    419: 
1.153     brouard   420:   Revision 1.152  2014/06/18 17:54:09  brouard
                    421:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    422: 
1.152     brouard   423:   Revision 1.151  2014/06/18 16:43:30  brouard
                    424:   *** empty log message ***
                    425: 
1.151     brouard   426:   Revision 1.150  2014/06/18 16:42:35  brouard
                    427:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    428:   Author: brouard
                    429: 
1.150     brouard   430:   Revision 1.149  2014/06/18 15:51:14  brouard
                    431:   Summary: Some fixes in parameter files errors
                    432:   Author: Nicolas Brouard
                    433: 
1.149     brouard   434:   Revision 1.148  2014/06/17 17:38:48  brouard
                    435:   Summary: Nothing new
                    436:   Author: Brouard
                    437: 
                    438:   Just a new packaging for OS/X version 0.98nS
                    439: 
1.148     brouard   440:   Revision 1.147  2014/06/16 10:33:11  brouard
                    441:   *** empty log message ***
                    442: 
1.147     brouard   443:   Revision 1.146  2014/06/16 10:20:28  brouard
                    444:   Summary: Merge
                    445:   Author: Brouard
                    446: 
                    447:   Merge, before building revised version.
                    448: 
1.146     brouard   449:   Revision 1.145  2014/06/10 21:23:15  brouard
                    450:   Summary: Debugging with valgrind
                    451:   Author: Nicolas Brouard
                    452: 
                    453:   Lot of changes in order to output the results with some covariates
                    454:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    455:   improve the code.
                    456:   No more memory valgrind error but a lot has to be done in order to
                    457:   continue the work of splitting the code into subroutines.
                    458:   Also, decodemodel has been improved. Tricode is still not
                    459:   optimal. nbcode should be improved. Documentation has been added in
                    460:   the source code.
                    461: 
1.144     brouard   462:   Revision 1.143  2014/01/26 09:45:38  brouard
                    463:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    464: 
                    465:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    466:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    467: 
1.143     brouard   468:   Revision 1.142  2014/01/26 03:57:36  brouard
                    469:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    470: 
                    471:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    472: 
1.142     brouard   473:   Revision 1.141  2014/01/26 02:42:01  brouard
                    474:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    475: 
1.141     brouard   476:   Revision 1.140  2011/09/02 10:37:54  brouard
                    477:   Summary: times.h is ok with mingw32 now.
                    478: 
1.140     brouard   479:   Revision 1.139  2010/06/14 07:50:17  brouard
                    480:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    481:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    482: 
1.139     brouard   483:   Revision 1.138  2010/04/30 18:19:40  brouard
                    484:   *** empty log message ***
                    485: 
1.138     brouard   486:   Revision 1.137  2010/04/29 18:11:38  brouard
                    487:   (Module): Checking covariates for more complex models
                    488:   than V1+V2. A lot of change to be done. Unstable.
                    489: 
1.137     brouard   490:   Revision 1.136  2010/04/26 20:30:53  brouard
                    491:   (Module): merging some libgsl code. Fixing computation
                    492:   of likelione (using inter/intrapolation if mle = 0) in order to
                    493:   get same likelihood as if mle=1.
                    494:   Some cleaning of code and comments added.
                    495: 
1.136     brouard   496:   Revision 1.135  2009/10/29 15:33:14  brouard
                    497:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    498: 
1.135     brouard   499:   Revision 1.134  2009/10/29 13:18:53  brouard
                    500:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    501: 
1.134     brouard   502:   Revision 1.133  2009/07/06 10:21:25  brouard
                    503:   just nforces
                    504: 
1.133     brouard   505:   Revision 1.132  2009/07/06 08:22:05  brouard
                    506:   Many tings
                    507: 
1.132     brouard   508:   Revision 1.131  2009/06/20 16:22:47  brouard
                    509:   Some dimensions resccaled
                    510: 
1.131     brouard   511:   Revision 1.130  2009/05/26 06:44:34  brouard
                    512:   (Module): Max Covariate is now set to 20 instead of 8. A
                    513:   lot of cleaning with variables initialized to 0. Trying to make
                    514:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    515: 
1.130     brouard   516:   Revision 1.129  2007/08/31 13:49:27  lievre
                    517:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    518: 
1.129     lievre    519:   Revision 1.128  2006/06/30 13:02:05  brouard
                    520:   (Module): Clarifications on computing e.j
                    521: 
1.128     brouard   522:   Revision 1.127  2006/04/28 18:11:50  brouard
                    523:   (Module): Yes the sum of survivors was wrong since
                    524:   imach-114 because nhstepm was no more computed in the age
                    525:   loop. Now we define nhstepma in the age loop.
                    526:   (Module): In order to speed up (in case of numerous covariates) we
                    527:   compute health expectancies (without variances) in a first step
                    528:   and then all the health expectancies with variances or standard
                    529:   deviation (needs data from the Hessian matrices) which slows the
                    530:   computation.
                    531:   In the future we should be able to stop the program is only health
                    532:   expectancies and graph are needed without standard deviations.
                    533: 
1.127     brouard   534:   Revision 1.126  2006/04/28 17:23:28  brouard
                    535:   (Module): Yes the sum of survivors was wrong since
                    536:   imach-114 because nhstepm was no more computed in the age
                    537:   loop. Now we define nhstepma in the age loop.
                    538:   Version 0.98h
                    539: 
1.126     brouard   540:   Revision 1.125  2006/04/04 15:20:31  lievre
                    541:   Errors in calculation of health expectancies. Age was not initialized.
                    542:   Forecasting file added.
                    543: 
                    544:   Revision 1.124  2006/03/22 17:13:53  lievre
                    545:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    546:   The log-likelihood is printed in the log file
                    547: 
                    548:   Revision 1.123  2006/03/20 10:52:43  brouard
                    549:   * imach.c (Module): <title> changed, corresponds to .htm file
                    550:   name. <head> headers where missing.
                    551: 
                    552:   * imach.c (Module): Weights can have a decimal point as for
                    553:   English (a comma might work with a correct LC_NUMERIC environment,
                    554:   otherwise the weight is truncated).
                    555:   Modification of warning when the covariates values are not 0 or
                    556:   1.
                    557:   Version 0.98g
                    558: 
                    559:   Revision 1.122  2006/03/20 09:45:41  brouard
                    560:   (Module): Weights can have a decimal point as for
                    561:   English (a comma might work with a correct LC_NUMERIC environment,
                    562:   otherwise the weight is truncated).
                    563:   Modification of warning when the covariates values are not 0 or
                    564:   1.
                    565:   Version 0.98g
                    566: 
                    567:   Revision 1.121  2006/03/16 17:45:01  lievre
                    568:   * imach.c (Module): Comments concerning covariates added
                    569: 
                    570:   * imach.c (Module): refinements in the computation of lli if
                    571:   status=-2 in order to have more reliable computation if stepm is
                    572:   not 1 month. Version 0.98f
                    573: 
                    574:   Revision 1.120  2006/03/16 15:10:38  lievre
                    575:   (Module): refinements in the computation of lli if
                    576:   status=-2 in order to have more reliable computation if stepm is
                    577:   not 1 month. Version 0.98f
                    578: 
                    579:   Revision 1.119  2006/03/15 17:42:26  brouard
                    580:   (Module): Bug if status = -2, the loglikelihood was
                    581:   computed as likelihood omitting the logarithm. Version O.98e
                    582: 
                    583:   Revision 1.118  2006/03/14 18:20:07  brouard
                    584:   (Module): varevsij Comments added explaining the second
                    585:   table of variances if popbased=1 .
                    586:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    587:   (Module): Function pstamp added
                    588:   (Module): Version 0.98d
                    589: 
                    590:   Revision 1.117  2006/03/14 17:16:22  brouard
                    591:   (Module): varevsij Comments added explaining the second
                    592:   table of variances if popbased=1 .
                    593:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    594:   (Module): Function pstamp added
                    595:   (Module): Version 0.98d
                    596: 
                    597:   Revision 1.116  2006/03/06 10:29:27  brouard
                    598:   (Module): Variance-covariance wrong links and
                    599:   varian-covariance of ej. is needed (Saito).
                    600: 
                    601:   Revision 1.115  2006/02/27 12:17:45  brouard
                    602:   (Module): One freematrix added in mlikeli! 0.98c
                    603: 
                    604:   Revision 1.114  2006/02/26 12:57:58  brouard
                    605:   (Module): Some improvements in processing parameter
                    606:   filename with strsep.
                    607: 
                    608:   Revision 1.113  2006/02/24 14:20:24  brouard
                    609:   (Module): Memory leaks checks with valgrind and:
                    610:   datafile was not closed, some imatrix were not freed and on matrix
                    611:   allocation too.
                    612: 
                    613:   Revision 1.112  2006/01/30 09:55:26  brouard
                    614:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    615: 
                    616:   Revision 1.111  2006/01/25 20:38:18  brouard
                    617:   (Module): Lots of cleaning and bugs added (Gompertz)
                    618:   (Module): Comments can be added in data file. Missing date values
                    619:   can be a simple dot '.'.
                    620: 
                    621:   Revision 1.110  2006/01/25 00:51:50  brouard
                    622:   (Module): Lots of cleaning and bugs added (Gompertz)
                    623: 
                    624:   Revision 1.109  2006/01/24 19:37:15  brouard
                    625:   (Module): Comments (lines starting with a #) are allowed in data.
                    626: 
                    627:   Revision 1.108  2006/01/19 18:05:42  lievre
                    628:   Gnuplot problem appeared...
                    629:   To be fixed
                    630: 
                    631:   Revision 1.107  2006/01/19 16:20:37  brouard
                    632:   Test existence of gnuplot in imach path
                    633: 
                    634:   Revision 1.106  2006/01/19 13:24:36  brouard
                    635:   Some cleaning and links added in html output
                    636: 
                    637:   Revision 1.105  2006/01/05 20:23:19  lievre
                    638:   *** empty log message ***
                    639: 
                    640:   Revision 1.104  2005/09/30 16:11:43  lievre
                    641:   (Module): sump fixed, loop imx fixed, and simplifications.
                    642:   (Module): If the status is missing at the last wave but we know
                    643:   that the person is alive, then we can code his/her status as -2
                    644:   (instead of missing=-1 in earlier versions) and his/her
                    645:   contributions to the likelihood is 1 - Prob of dying from last
                    646:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    647:   the healthy state at last known wave). Version is 0.98
                    648: 
                    649:   Revision 1.103  2005/09/30 15:54:49  lievre
                    650:   (Module): sump fixed, loop imx fixed, and simplifications.
                    651: 
                    652:   Revision 1.102  2004/09/15 17:31:30  brouard
                    653:   Add the possibility to read data file including tab characters.
                    654: 
                    655:   Revision 1.101  2004/09/15 10:38:38  brouard
                    656:   Fix on curr_time
                    657: 
                    658:   Revision 1.100  2004/07/12 18:29:06  brouard
                    659:   Add version for Mac OS X. Just define UNIX in Makefile
                    660: 
                    661:   Revision 1.99  2004/06/05 08:57:40  brouard
                    662:   *** empty log message ***
                    663: 
                    664:   Revision 1.98  2004/05/16 15:05:56  brouard
                    665:   New version 0.97 . First attempt to estimate force of mortality
                    666:   directly from the data i.e. without the need of knowing the health
                    667:   state at each age, but using a Gompertz model: log u =a + b*age .
                    668:   This is the basic analysis of mortality and should be done before any
                    669:   other analysis, in order to test if the mortality estimated from the
                    670:   cross-longitudinal survey is different from the mortality estimated
                    671:   from other sources like vital statistic data.
                    672: 
                    673:   The same imach parameter file can be used but the option for mle should be -3.
                    674: 
1.133     brouard   675:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   676:   former routines in order to include the new code within the former code.
                    677: 
                    678:   The output is very simple: only an estimate of the intercept and of
                    679:   the slope with 95% confident intervals.
                    680: 
                    681:   Current limitations:
                    682:   A) Even if you enter covariates, i.e. with the
                    683:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    684:   B) There is no computation of Life Expectancy nor Life Table.
                    685: 
                    686:   Revision 1.97  2004/02/20 13:25:42  lievre
                    687:   Version 0.96d. Population forecasting command line is (temporarily)
                    688:   suppressed.
                    689: 
                    690:   Revision 1.96  2003/07/15 15:38:55  brouard
                    691:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    692:   rewritten within the same printf. Workaround: many printfs.
                    693: 
                    694:   Revision 1.95  2003/07/08 07:54:34  brouard
                    695:   * imach.c (Repository):
                    696:   (Repository): Using imachwizard code to output a more meaningful covariance
                    697:   matrix (cov(a12,c31) instead of numbers.
                    698: 
                    699:   Revision 1.94  2003/06/27 13:00:02  brouard
                    700:   Just cleaning
                    701: 
                    702:   Revision 1.93  2003/06/25 16:33:55  brouard
                    703:   (Module): On windows (cygwin) function asctime_r doesn't
                    704:   exist so I changed back to asctime which exists.
                    705:   (Module): Version 0.96b
                    706: 
                    707:   Revision 1.92  2003/06/25 16:30:45  brouard
                    708:   (Module): On windows (cygwin) function asctime_r doesn't
                    709:   exist so I changed back to asctime which exists.
                    710: 
                    711:   Revision 1.91  2003/06/25 15:30:29  brouard
                    712:   * imach.c (Repository): Duplicated warning errors corrected.
                    713:   (Repository): Elapsed time after each iteration is now output. It
                    714:   helps to forecast when convergence will be reached. Elapsed time
                    715:   is stamped in powell.  We created a new html file for the graphs
                    716:   concerning matrix of covariance. It has extension -cov.htm.
                    717: 
                    718:   Revision 1.90  2003/06/24 12:34:15  brouard
                    719:   (Module): Some bugs corrected for windows. Also, when
                    720:   mle=-1 a template is output in file "or"mypar.txt with the design
                    721:   of the covariance matrix to be input.
                    722: 
                    723:   Revision 1.89  2003/06/24 12:30:52  brouard
                    724:   (Module): Some bugs corrected for windows. Also, when
                    725:   mle=-1 a template is output in file "or"mypar.txt with the design
                    726:   of the covariance matrix to be input.
                    727: 
                    728:   Revision 1.88  2003/06/23 17:54:56  brouard
                    729:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    730: 
                    731:   Revision 1.87  2003/06/18 12:26:01  brouard
                    732:   Version 0.96
                    733: 
                    734:   Revision 1.86  2003/06/17 20:04:08  brouard
                    735:   (Module): Change position of html and gnuplot routines and added
                    736:   routine fileappend.
                    737: 
                    738:   Revision 1.85  2003/06/17 13:12:43  brouard
                    739:   * imach.c (Repository): Check when date of death was earlier that
                    740:   current date of interview. It may happen when the death was just
                    741:   prior to the death. In this case, dh was negative and likelihood
                    742:   was wrong (infinity). We still send an "Error" but patch by
                    743:   assuming that the date of death was just one stepm after the
                    744:   interview.
                    745:   (Repository): Because some people have very long ID (first column)
                    746:   we changed int to long in num[] and we added a new lvector for
                    747:   memory allocation. But we also truncated to 8 characters (left
                    748:   truncation)
                    749:   (Repository): No more line truncation errors.
                    750: 
                    751:   Revision 1.84  2003/06/13 21:44:43  brouard
                    752:   * imach.c (Repository): Replace "freqsummary" at a correct
                    753:   place. It differs from routine "prevalence" which may be called
                    754:   many times. Probs is memory consuming and must be used with
                    755:   parcimony.
                    756:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    757: 
                    758:   Revision 1.83  2003/06/10 13:39:11  lievre
                    759:   *** empty log message ***
                    760: 
                    761:   Revision 1.82  2003/06/05 15:57:20  brouard
                    762:   Add log in  imach.c and  fullversion number is now printed.
                    763: 
                    764: */
                    765: /*
                    766:    Interpolated Markov Chain
                    767: 
                    768:   Short summary of the programme:
                    769:   
1.227     brouard   770:   This program computes Healthy Life Expectancies or State-specific
                    771:   (if states aren't health statuses) Expectancies from
                    772:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    773: 
                    774:   -1- a first survey ("cross") where individuals from different ages
                    775:   are interviewed on their health status or degree of disability (in
                    776:   the case of a health survey which is our main interest)
                    777: 
                    778:   -2- at least a second wave of interviews ("longitudinal") which
                    779:   measure each change (if any) in individual health status.  Health
                    780:   expectancies are computed from the time spent in each health state
                    781:   according to a model. More health states you consider, more time is
                    782:   necessary to reach the Maximum Likelihood of the parameters involved
                    783:   in the model.  The simplest model is the multinomial logistic model
                    784:   where pij is the probability to be observed in state j at the second
                    785:   wave conditional to be observed in state i at the first
                    786:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    787:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    788:   have a more complex model than "constant and age", you should modify
                    789:   the program where the markup *Covariates have to be included here
                    790:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   791:   convergence.
                    792: 
                    793:   The advantage of this computer programme, compared to a simple
                    794:   multinomial logistic model, is clear when the delay between waves is not
                    795:   identical for each individual. Also, if a individual missed an
                    796:   intermediate interview, the information is lost, but taken into
                    797:   account using an interpolation or extrapolation.  
                    798: 
                    799:   hPijx is the probability to be observed in state i at age x+h
                    800:   conditional to the observed state i at age x. The delay 'h' can be
                    801:   split into an exact number (nh*stepm) of unobserved intermediate
                    802:   states. This elementary transition (by month, quarter,
                    803:   semester or year) is modelled as a multinomial logistic.  The hPx
                    804:   matrix is simply the matrix product of nh*stepm elementary matrices
                    805:   and the contribution of each individual to the likelihood is simply
                    806:   hPijx.
                    807: 
                    808:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   809:   of the life expectancies. It also computes the period (stable) prevalence.
                    810: 
                    811: Back prevalence and projections:
1.227     brouard   812: 
                    813:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    814:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    815:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    816:    mobilavproj)
                    817: 
                    818:     Computes the back prevalence limit for any combination of
                    819:     covariate values k at any age between ageminpar and agemaxpar and
                    820:     returns it in **bprlim. In the loops,
                    821: 
                    822:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    823:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    824: 
                    825:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   826:    Computes for any combination of covariates k and any age between bage and fage 
                    827:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    828:                        oldm=oldms;savm=savms;
1.227     brouard   829: 
1.267     brouard   830:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   831:      Computes the transition matrix starting at age 'age' over
                    832:      'nhstepm*hstepm*stepm' months (i.e. until
                    833:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   834:      nhstepm*hstepm matrices. 
                    835: 
                    836:      Returns p3mat[i][j][h] after calling
                    837:      p3mat[i][j][h]=matprod2(newm,
                    838:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    839:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    840:      oldm);
1.226     brouard   841: 
                    842: Important routines
                    843: 
                    844: - func (or funcone), computes logit (pij) distinguishing
                    845:   o fixed variables (single or product dummies or quantitative);
                    846:   o varying variables by:
                    847:    (1) wave (single, product dummies, quantitative), 
                    848:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    849:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    850:        % varying dummy (not done) or quantitative (not done);
                    851: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    852:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    853: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    854:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    855:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   856: 
1.226     brouard   857: 
                    858:   
1.133     brouard   859:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    860:            Institut national d'études démographiques, Paris.
1.126     brouard   861:   This software have been partly granted by Euro-REVES, a concerted action
                    862:   from the European Union.
                    863:   It is copyrighted identically to a GNU software product, ie programme and
                    864:   software can be distributed freely for non commercial use. Latest version
                    865:   can be accessed at http://euroreves.ined.fr/imach .
                    866: 
                    867:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    868:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    869:   
                    870:   **********************************************************************/
                    871: /*
                    872:   main
                    873:   read parameterfile
                    874:   read datafile
                    875:   concatwav
                    876:   freqsummary
                    877:   if (mle >= 1)
                    878:     mlikeli
                    879:   print results files
                    880:   if mle==1 
                    881:      computes hessian
                    882:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    883:       begin-prev-date,...
                    884:   open gnuplot file
                    885:   open html file
1.145     brouard   886:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    887:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    888:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    889:     freexexit2 possible for memory heap.
                    890: 
                    891:   h Pij x                         | pij_nom  ficrestpij
                    892:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    893:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    894:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    895: 
                    896:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    897:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    898:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    899:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    900:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    901: 
1.126     brouard   902:   forecasting if prevfcast==1 prevforecast call prevalence()
                    903:   health expectancies
                    904:   Variance-covariance of DFLE
                    905:   prevalence()
                    906:    movingaverage()
                    907:   varevsij() 
                    908:   if popbased==1 varevsij(,popbased)
                    909:   total life expectancies
                    910:   Variance of period (stable) prevalence
                    911:  end
                    912: */
                    913: 
1.187     brouard   914: /* #define DEBUG */
                    915: /* #define DEBUGBRENT */
1.203     brouard   916: /* #define DEBUGLINMIN */
                    917: /* #define DEBUGHESS */
                    918: #define DEBUGHESSIJ
1.224     brouard   919: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   920: #define POWELL /* Instead of NLOPT */
1.224     brouard   921: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   922: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    923: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   924: 
                    925: #include <math.h>
                    926: #include <stdio.h>
                    927: #include <stdlib.h>
                    928: #include <string.h>
1.226     brouard   929: #include <ctype.h>
1.159     brouard   930: 
                    931: #ifdef _WIN32
                    932: #include <io.h>
1.172     brouard   933: #include <windows.h>
                    934: #include <tchar.h>
1.159     brouard   935: #else
1.126     brouard   936: #include <unistd.h>
1.159     brouard   937: #endif
1.126     brouard   938: 
                    939: #include <limits.h>
                    940: #include <sys/types.h>
1.171     brouard   941: 
                    942: #if defined(__GNUC__)
                    943: #include <sys/utsname.h> /* Doesn't work on Windows */
                    944: #endif
                    945: 
1.126     brouard   946: #include <sys/stat.h>
                    947: #include <errno.h>
1.159     brouard   948: /* extern int errno; */
1.126     brouard   949: 
1.157     brouard   950: /* #ifdef LINUX */
                    951: /* #include <time.h> */
                    952: /* #include "timeval.h" */
                    953: /* #else */
                    954: /* #include <sys/time.h> */
                    955: /* #endif */
                    956: 
1.126     brouard   957: #include <time.h>
                    958: 
1.136     brouard   959: #ifdef GSL
                    960: #include <gsl/gsl_errno.h>
                    961: #include <gsl/gsl_multimin.h>
                    962: #endif
                    963: 
1.167     brouard   964: 
1.162     brouard   965: #ifdef NLOPT
                    966: #include <nlopt.h>
                    967: typedef struct {
                    968:   double (* function)(double [] );
                    969: } myfunc_data ;
                    970: #endif
                    971: 
1.126     brouard   972: /* #include <libintl.h> */
                    973: /* #define _(String) gettext (String) */
                    974: 
1.251     brouard   975: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   976: 
                    977: #define GNUPLOTPROGRAM "gnuplot"
                    978: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    979: #define FILENAMELENGTH 132
                    980: 
                    981: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    982: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    983: 
1.144     brouard   984: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    985: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   986: 
                    987: #define NINTERVMAX 8
1.144     brouard   988: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    989: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    990: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   991: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   992: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    993: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   994: #define MAXN 20000
1.144     brouard   995: #define YEARM 12. /**< Number of months per year */
1.218     brouard   996: /* #define AGESUP 130 */
                    997: #define AGESUP 150
1.268     brouard   998: #define AGEINF 0
1.218     brouard   999: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1000: #define AGEBASE 40
1.194     brouard  1001: #define AGEOVERFLOW 1.e20
1.164     brouard  1002: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1003: #ifdef _WIN32
                   1004: #define DIRSEPARATOR '\\'
                   1005: #define CHARSEPARATOR "\\"
                   1006: #define ODIRSEPARATOR '/'
                   1007: #else
1.126     brouard  1008: #define DIRSEPARATOR '/'
                   1009: #define CHARSEPARATOR "/"
                   1010: #define ODIRSEPARATOR '\\'
                   1011: #endif
                   1012: 
1.270   ! brouard  1013: /* $Id: imach.c,v 1.269 2017/05/23 08:39:25 brouard Exp $ */
1.126     brouard  1014: /* $State: Exp $ */
1.196     brouard  1015: #include "version.h"
                   1016: char version[]=__IMACH_VERSION__;
1.224     brouard  1017: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.270   ! brouard  1018: char fullversion[]="$Revision: 1.269 $ $Date: 2017/05/23 08:39:25 $"; 
1.126     brouard  1019: char strstart[80];
                   1020: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1021: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1022: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1023: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1024: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1025: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1026: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1027: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1028: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1029: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1030: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1031: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1032: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1033: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1034: int nsd=0; /**< Total number of single dummy variables (output) */
                   1035: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1036: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1037: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1038: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1039: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1040: int cptcov=0; /* Working variable */
1.218     brouard  1041: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1042: int npar=NPARMAX;
                   1043: int nlstate=2; /* Number of live states */
                   1044: int ndeath=1; /* Number of dead states */
1.130     brouard  1045: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1046: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1047: int popbased=0;
                   1048: 
                   1049: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1050: int maxwav=0; /* Maxim number of waves */
                   1051: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1052: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1053: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1054:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1055: int mle=1, weightopt=0;
1.126     brouard  1056: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1057: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1058: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1059:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1060: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1061: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1062: 
1.130     brouard  1063: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1064: double **matprod2(); /* test */
1.126     brouard  1065: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1066: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1067: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1068: 
1.136     brouard  1069: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1070: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1071: FILE *ficlog, *ficrespow;
1.130     brouard  1072: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1073: double fretone; /* Only one call to likelihood */
1.130     brouard  1074: long ipmx=0; /* Number of contributions */
1.126     brouard  1075: double sw; /* Sum of weights */
                   1076: char filerespow[FILENAMELENGTH];
                   1077: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1078: FILE *ficresilk;
                   1079: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1080: FILE *ficresprobmorprev;
                   1081: FILE *fichtm, *fichtmcov; /* Html File */
                   1082: FILE *ficreseij;
                   1083: char filerese[FILENAMELENGTH];
                   1084: FILE *ficresstdeij;
                   1085: char fileresstde[FILENAMELENGTH];
                   1086: FILE *ficrescveij;
                   1087: char filerescve[FILENAMELENGTH];
                   1088: FILE  *ficresvij;
                   1089: char fileresv[FILENAMELENGTH];
1.269     brouard  1090: 
1.126     brouard  1091: char title[MAXLINE];
1.234     brouard  1092: char model[MAXLINE]; /**< The model line */
1.217     brouard  1093: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1094: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1095: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1096: char command[FILENAMELENGTH];
                   1097: int  outcmd=0;
                   1098: 
1.217     brouard  1099: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1100: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1101: char filelog[FILENAMELENGTH]; /* Log file */
                   1102: char filerest[FILENAMELENGTH];
                   1103: char fileregp[FILENAMELENGTH];
                   1104: char popfile[FILENAMELENGTH];
                   1105: 
                   1106: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1107: 
1.157     brouard  1108: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1109: /* struct timezone tzp; */
                   1110: /* extern int gettimeofday(); */
                   1111: struct tm tml, *gmtime(), *localtime();
                   1112: 
                   1113: extern time_t time();
                   1114: 
                   1115: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1116: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1117: struct tm tm;
                   1118: 
1.126     brouard  1119: char strcurr[80], strfor[80];
                   1120: 
                   1121: char *endptr;
                   1122: long lval;
                   1123: double dval;
                   1124: 
                   1125: #define NR_END 1
                   1126: #define FREE_ARG char*
                   1127: #define FTOL 1.0e-10
                   1128: 
                   1129: #define NRANSI 
1.240     brouard  1130: #define ITMAX 200
                   1131: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1132: 
                   1133: #define TOL 2.0e-4 
                   1134: 
                   1135: #define CGOLD 0.3819660 
                   1136: #define ZEPS 1.0e-10 
                   1137: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1138: 
                   1139: #define GOLD 1.618034 
                   1140: #define GLIMIT 100.0 
                   1141: #define TINY 1.0e-20 
                   1142: 
                   1143: static double maxarg1,maxarg2;
                   1144: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1145: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1146:   
                   1147: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1148: #define rint(a) floor(a+0.5)
1.166     brouard  1149: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1150: #define mytinydouble 1.0e-16
1.166     brouard  1151: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1152: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1153: /* static double dsqrarg; */
                   1154: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1155: static double sqrarg;
                   1156: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1157: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1158: int agegomp= AGEGOMP;
                   1159: 
                   1160: int imx; 
                   1161: int stepm=1;
                   1162: /* Stepm, step in month: minimum step interpolation*/
                   1163: 
                   1164: int estepm;
                   1165: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1166: 
                   1167: int m,nb;
                   1168: long *num;
1.197     brouard  1169: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1170: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1171:                   covariate for which somebody answered excluding 
                   1172:                   undefined. Usually 2: 0 and 1. */
                   1173: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1174:                             covariate for which somebody answered including 
                   1175:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1176: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1177: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1178: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1179: double *ageexmed,*agecens;
                   1180: double dateintmean=0;
                   1181: 
                   1182: double *weight;
                   1183: int **s; /* Status */
1.141     brouard  1184: double *agedc;
1.145     brouard  1185: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1186:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1187:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1188: double **coqvar; /* Fixed quantitative covariate nqv */
                   1189: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1190: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1191: double  idx; 
                   1192: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1193: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1194: /*k          1  2   3   4     5    6    7     8    9 */
                   1195: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1196: /* Tndvar[k]    1   2   3               4          5 */
                   1197: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1198: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1199: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1200: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1201: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1202: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1203: /* Tprod[i]=k           4               7            */
                   1204: /* Tage[i]=k                  5               8      */
                   1205: /* */
                   1206: /* Type                    */
                   1207: /* V         1  2  3  4  5 */
                   1208: /*           F  F  V  V  V */
                   1209: /*           D  Q  D  D  Q */
                   1210: /*                         */
                   1211: int *TvarsD;
                   1212: int *TvarsDind;
                   1213: int *TvarsQ;
                   1214: int *TvarsQind;
                   1215: 
1.235     brouard  1216: #define MAXRESULTLINES 10
                   1217: int nresult=0;
1.258     brouard  1218: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1219: int TKresult[MAXRESULTLINES];
1.237     brouard  1220: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1221: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1222: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1223: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1224: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1225: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1226: 
1.234     brouard  1227: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1228: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1229: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1230: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1231: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1232: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1233: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1234: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1235: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1236: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1237: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1238: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1239: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1240: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1241: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1242: 
1.230     brouard  1243: int *Tvarsel; /**< Selected covariates for output */
                   1244: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1245: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1246: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1247: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1248: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1249: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1250: int *Tage;
1.227     brouard  1251: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1252: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1253: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1254: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1255: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1256: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1257: int **Tvard;
                   1258: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1259: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1260: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1261:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1262:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1263: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1264: double *lsurv, *lpop, *tpop;
                   1265: 
1.231     brouard  1266: #define FD 1; /* Fixed dummy covariate */
                   1267: #define FQ 2; /* Fixed quantitative covariate */
                   1268: #define FP 3; /* Fixed product covariate */
                   1269: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1270: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1271: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1272: #define VD 10; /* Varying dummy covariate */
                   1273: #define VQ 11; /* Varying quantitative covariate */
                   1274: #define VP 12; /* Varying product covariate */
                   1275: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1276: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1277: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1278: #define APFD 16; /* Age product * fixed dummy covariate */
                   1279: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1280: #define APVD 18; /* Age product * varying dummy covariate */
                   1281: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1282: 
                   1283: #define FTYPE 1; /* Fixed covariate */
                   1284: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1285: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1286: 
                   1287: struct kmodel{
                   1288:        int maintype; /* main type */
                   1289:        int subtype; /* subtype */
                   1290: };
                   1291: struct kmodel modell[NCOVMAX];
                   1292: 
1.143     brouard  1293: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1294: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1295: 
                   1296: /**************** split *************************/
                   1297: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1298: {
                   1299:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1300:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1301:   */ 
                   1302:   char *ss;                            /* pointer */
1.186     brouard  1303:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1304: 
                   1305:   l1 = strlen(path );                  /* length of path */
                   1306:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1307:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1308:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1309:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1310:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1311:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1312:     /* get current working directory */
                   1313:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1314: #ifdef WIN32
                   1315:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1316: #else
                   1317:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1318: #endif
1.126     brouard  1319:       return( GLOCK_ERROR_GETCWD );
                   1320:     }
                   1321:     /* got dirc from getcwd*/
                   1322:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1323:   } else {                             /* strip directory from path */
1.126     brouard  1324:     ss++;                              /* after this, the filename */
                   1325:     l2 = strlen( ss );                 /* length of filename */
                   1326:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1327:     strcpy( name, ss );                /* save file name */
                   1328:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1329:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1330:     printf(" DIRC2 = %s \n",dirc);
                   1331:   }
                   1332:   /* We add a separator at the end of dirc if not exists */
                   1333:   l1 = strlen( dirc );                 /* length of directory */
                   1334:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1335:     dirc[l1] =  DIRSEPARATOR;
                   1336:     dirc[l1+1] = 0; 
                   1337:     printf(" DIRC3 = %s \n",dirc);
                   1338:   }
                   1339:   ss = strrchr( name, '.' );           /* find last / */
                   1340:   if (ss >0){
                   1341:     ss++;
                   1342:     strcpy(ext,ss);                    /* save extension */
                   1343:     l1= strlen( name);
                   1344:     l2= strlen(ss)+1;
                   1345:     strncpy( finame, name, l1-l2);
                   1346:     finame[l1-l2]= 0;
                   1347:   }
                   1348: 
                   1349:   return( 0 );                         /* we're done */
                   1350: }
                   1351: 
                   1352: 
                   1353: /******************************************/
                   1354: 
                   1355: void replace_back_to_slash(char *s, char*t)
                   1356: {
                   1357:   int i;
                   1358:   int lg=0;
                   1359:   i=0;
                   1360:   lg=strlen(t);
                   1361:   for(i=0; i<= lg; i++) {
                   1362:     (s[i] = t[i]);
                   1363:     if (t[i]== '\\') s[i]='/';
                   1364:   }
                   1365: }
                   1366: 
1.132     brouard  1367: char *trimbb(char *out, char *in)
1.137     brouard  1368: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1369:   char *s;
                   1370:   s=out;
                   1371:   while (*in != '\0'){
1.137     brouard  1372:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1373:       in++;
                   1374:     }
                   1375:     *out++ = *in++;
                   1376:   }
                   1377:   *out='\0';
                   1378:   return s;
                   1379: }
                   1380: 
1.187     brouard  1381: /* char *substrchaine(char *out, char *in, char *chain) */
                   1382: /* { */
                   1383: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1384: /*   char *s, *t; */
                   1385: /*   t=in;s=out; */
                   1386: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1387: /*     *out++ = *in++; */
                   1388: /*   } */
                   1389: 
                   1390: /*   /\* *in matches *chain *\/ */
                   1391: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1392: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1393: /*   } */
                   1394: /*   in--; chain--; */
                   1395: /*   while ( (*in != '\0')){ */
                   1396: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1397: /*     *out++ = *in++; */
                   1398: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1399: /*   } */
                   1400: /*   *out='\0'; */
                   1401: /*   out=s; */
                   1402: /*   return out; */
                   1403: /* } */
                   1404: char *substrchaine(char *out, char *in, char *chain)
                   1405: {
                   1406:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1407:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1408: 
                   1409:   char *strloc;
                   1410: 
                   1411:   strcpy (out, in); 
                   1412:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1413:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1414:   if(strloc != NULL){ 
                   1415:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1416:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1417:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1418:   }
                   1419:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1420:   return out;
                   1421: }
                   1422: 
                   1423: 
1.145     brouard  1424: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1425: {
1.187     brouard  1426:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1427:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1428:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1429:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1430:   */
1.160     brouard  1431:   char *s, *t;
1.145     brouard  1432:   t=in;s=in;
                   1433:   while ((*in != occ) && (*in != '\0')){
                   1434:     *alocc++ = *in++;
                   1435:   }
                   1436:   if( *in == occ){
                   1437:     *(alocc)='\0';
                   1438:     s=++in;
                   1439:   }
                   1440:  
                   1441:   if (s == t) {/* occ not found */
                   1442:     *(alocc-(in-s))='\0';
                   1443:     in=s;
                   1444:   }
                   1445:   while ( *in != '\0'){
                   1446:     *blocc++ = *in++;
                   1447:   }
                   1448: 
                   1449:   *blocc='\0';
                   1450:   return t;
                   1451: }
1.137     brouard  1452: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1453: {
1.187     brouard  1454:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1455:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1456:      gives blocc="abcdef2ghi" and alocc="j".
                   1457:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1458:   */
                   1459:   char *s, *t;
                   1460:   t=in;s=in;
                   1461:   while (*in != '\0'){
                   1462:     while( *in == occ){
                   1463:       *blocc++ = *in++;
                   1464:       s=in;
                   1465:     }
                   1466:     *blocc++ = *in++;
                   1467:   }
                   1468:   if (s == t) /* occ not found */
                   1469:     *(blocc-(in-s))='\0';
                   1470:   else
                   1471:     *(blocc-(in-s)-1)='\0';
                   1472:   in=s;
                   1473:   while ( *in != '\0'){
                   1474:     *alocc++ = *in++;
                   1475:   }
                   1476: 
                   1477:   *alocc='\0';
                   1478:   return s;
                   1479: }
                   1480: 
1.126     brouard  1481: int nbocc(char *s, char occ)
                   1482: {
                   1483:   int i,j=0;
                   1484:   int lg=20;
                   1485:   i=0;
                   1486:   lg=strlen(s);
                   1487:   for(i=0; i<= lg; i++) {
1.234     brouard  1488:     if  (s[i] == occ ) j++;
1.126     brouard  1489:   }
                   1490:   return j;
                   1491: }
                   1492: 
1.137     brouard  1493: /* void cutv(char *u,char *v, char*t, char occ) */
                   1494: /* { */
                   1495: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1496: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1497: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1498: /*   int i,lg,j,p=0; */
                   1499: /*   i=0; */
                   1500: /*   lg=strlen(t); */
                   1501: /*   for(j=0; j<=lg-1; j++) { */
                   1502: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1503: /*   } */
1.126     brouard  1504: 
1.137     brouard  1505: /*   for(j=0; j<p; j++) { */
                   1506: /*     (u[j] = t[j]); */
                   1507: /*   } */
                   1508: /*      u[p]='\0'; */
1.126     brouard  1509: 
1.137     brouard  1510: /*    for(j=0; j<= lg; j++) { */
                   1511: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1512: /*   } */
                   1513: /* } */
1.126     brouard  1514: 
1.160     brouard  1515: #ifdef _WIN32
                   1516: char * strsep(char **pp, const char *delim)
                   1517: {
                   1518:   char *p, *q;
                   1519:          
                   1520:   if ((p = *pp) == NULL)
                   1521:     return 0;
                   1522:   if ((q = strpbrk (p, delim)) != NULL)
                   1523:   {
                   1524:     *pp = q + 1;
                   1525:     *q = '\0';
                   1526:   }
                   1527:   else
                   1528:     *pp = 0;
                   1529:   return p;
                   1530: }
                   1531: #endif
                   1532: 
1.126     brouard  1533: /********************** nrerror ********************/
                   1534: 
                   1535: void nrerror(char error_text[])
                   1536: {
                   1537:   fprintf(stderr,"ERREUR ...\n");
                   1538:   fprintf(stderr,"%s\n",error_text);
                   1539:   exit(EXIT_FAILURE);
                   1540: }
                   1541: /*********************** vector *******************/
                   1542: double *vector(int nl, int nh)
                   1543: {
                   1544:   double *v;
                   1545:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1546:   if (!v) nrerror("allocation failure in vector");
                   1547:   return v-nl+NR_END;
                   1548: }
                   1549: 
                   1550: /************************ free vector ******************/
                   1551: void free_vector(double*v, int nl, int nh)
                   1552: {
                   1553:   free((FREE_ARG)(v+nl-NR_END));
                   1554: }
                   1555: 
                   1556: /************************ivector *******************************/
                   1557: int *ivector(long nl,long nh)
                   1558: {
                   1559:   int *v;
                   1560:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1561:   if (!v) nrerror("allocation failure in ivector");
                   1562:   return v-nl+NR_END;
                   1563: }
                   1564: 
                   1565: /******************free ivector **************************/
                   1566: void free_ivector(int *v, long nl, long nh)
                   1567: {
                   1568:   free((FREE_ARG)(v+nl-NR_END));
                   1569: }
                   1570: 
                   1571: /************************lvector *******************************/
                   1572: long *lvector(long nl,long nh)
                   1573: {
                   1574:   long *v;
                   1575:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1576:   if (!v) nrerror("allocation failure in ivector");
                   1577:   return v-nl+NR_END;
                   1578: }
                   1579: 
                   1580: /******************free lvector **************************/
                   1581: void free_lvector(long *v, long nl, long nh)
                   1582: {
                   1583:   free((FREE_ARG)(v+nl-NR_END));
                   1584: }
                   1585: 
                   1586: /******************* imatrix *******************************/
                   1587: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1588:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1589: { 
                   1590:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1591:   int **m; 
                   1592:   
                   1593:   /* allocate pointers to rows */ 
                   1594:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1595:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1596:   m += NR_END; 
                   1597:   m -= nrl; 
                   1598:   
                   1599:   
                   1600:   /* allocate rows and set pointers to them */ 
                   1601:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1602:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1603:   m[nrl] += NR_END; 
                   1604:   m[nrl] -= ncl; 
                   1605:   
                   1606:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1607:   
                   1608:   /* return pointer to array of pointers to rows */ 
                   1609:   return m; 
                   1610: } 
                   1611: 
                   1612: /****************** free_imatrix *************************/
                   1613: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1614:       int **m;
                   1615:       long nch,ncl,nrh,nrl; 
                   1616:      /* free an int matrix allocated by imatrix() */ 
                   1617: { 
                   1618:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1619:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1620: } 
                   1621: 
                   1622: /******************* matrix *******************************/
                   1623: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1624: {
                   1625:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1626:   double **m;
                   1627: 
                   1628:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1629:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1630:   m += NR_END;
                   1631:   m -= nrl;
                   1632: 
                   1633:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1634:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1635:   m[nrl] += NR_END;
                   1636:   m[nrl] -= ncl;
                   1637: 
                   1638:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1639:   return m;
1.145     brouard  1640:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1641: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1642: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1643:    */
                   1644: }
                   1645: 
                   1646: /*************************free matrix ************************/
                   1647: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1648: {
                   1649:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1650:   free((FREE_ARG)(m+nrl-NR_END));
                   1651: }
                   1652: 
                   1653: /******************* ma3x *******************************/
                   1654: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1655: {
                   1656:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1657:   double ***m;
                   1658: 
                   1659:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1660:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1661:   m += NR_END;
                   1662:   m -= nrl;
                   1663: 
                   1664:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1665:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1666:   m[nrl] += NR_END;
                   1667:   m[nrl] -= ncl;
                   1668: 
                   1669:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1670: 
                   1671:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1672:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1673:   m[nrl][ncl] += NR_END;
                   1674:   m[nrl][ncl] -= nll;
                   1675:   for (j=ncl+1; j<=nch; j++) 
                   1676:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1677:   
                   1678:   for (i=nrl+1; i<=nrh; i++) {
                   1679:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1680:     for (j=ncl+1; j<=nch; j++) 
                   1681:       m[i][j]=m[i][j-1]+nlay;
                   1682:   }
                   1683:   return m; 
                   1684:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1685:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1686:   */
                   1687: }
                   1688: 
                   1689: /*************************free ma3x ************************/
                   1690: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1691: {
                   1692:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1693:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1694:   free((FREE_ARG)(m+nrl-NR_END));
                   1695: }
                   1696: 
                   1697: /*************** function subdirf ***********/
                   1698: char *subdirf(char fileres[])
                   1699: {
                   1700:   /* Caution optionfilefiname is hidden */
                   1701:   strcpy(tmpout,optionfilefiname);
                   1702:   strcat(tmpout,"/"); /* Add to the right */
                   1703:   strcat(tmpout,fileres);
                   1704:   return tmpout;
                   1705: }
                   1706: 
                   1707: /*************** function subdirf2 ***********/
                   1708: char *subdirf2(char fileres[], char *preop)
                   1709: {
                   1710:   
                   1711:   /* Caution optionfilefiname is hidden */
                   1712:   strcpy(tmpout,optionfilefiname);
                   1713:   strcat(tmpout,"/");
                   1714:   strcat(tmpout,preop);
                   1715:   strcat(tmpout,fileres);
                   1716:   return tmpout;
                   1717: }
                   1718: 
                   1719: /*************** function subdirf3 ***********/
                   1720: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1721: {
                   1722:   
                   1723:   /* Caution optionfilefiname is hidden */
                   1724:   strcpy(tmpout,optionfilefiname);
                   1725:   strcat(tmpout,"/");
                   1726:   strcat(tmpout,preop);
                   1727:   strcat(tmpout,preop2);
                   1728:   strcat(tmpout,fileres);
                   1729:   return tmpout;
                   1730: }
1.213     brouard  1731:  
                   1732: /*************** function subdirfext ***********/
                   1733: char *subdirfext(char fileres[], char *preop, char *postop)
                   1734: {
                   1735:   
                   1736:   strcpy(tmpout,preop);
                   1737:   strcat(tmpout,fileres);
                   1738:   strcat(tmpout,postop);
                   1739:   return tmpout;
                   1740: }
1.126     brouard  1741: 
1.213     brouard  1742: /*************** function subdirfext3 ***********/
                   1743: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1744: {
                   1745:   
                   1746:   /* Caution optionfilefiname is hidden */
                   1747:   strcpy(tmpout,optionfilefiname);
                   1748:   strcat(tmpout,"/");
                   1749:   strcat(tmpout,preop);
                   1750:   strcat(tmpout,fileres);
                   1751:   strcat(tmpout,postop);
                   1752:   return tmpout;
                   1753: }
                   1754:  
1.162     brouard  1755: char *asc_diff_time(long time_sec, char ascdiff[])
                   1756: {
                   1757:   long sec_left, days, hours, minutes;
                   1758:   days = (time_sec) / (60*60*24);
                   1759:   sec_left = (time_sec) % (60*60*24);
                   1760:   hours = (sec_left) / (60*60) ;
                   1761:   sec_left = (sec_left) %(60*60);
                   1762:   minutes = (sec_left) /60;
                   1763:   sec_left = (sec_left) % (60);
                   1764:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1765:   return ascdiff;
                   1766: }
                   1767: 
1.126     brouard  1768: /***************** f1dim *************************/
                   1769: extern int ncom; 
                   1770: extern double *pcom,*xicom;
                   1771: extern double (*nrfunc)(double []); 
                   1772:  
                   1773: double f1dim(double x) 
                   1774: { 
                   1775:   int j; 
                   1776:   double f;
                   1777:   double *xt; 
                   1778:  
                   1779:   xt=vector(1,ncom); 
                   1780:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1781:   f=(*nrfunc)(xt); 
                   1782:   free_vector(xt,1,ncom); 
                   1783:   return f; 
                   1784: } 
                   1785: 
                   1786: /*****************brent *************************/
                   1787: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1788: {
                   1789:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1790:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1791:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1792:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1793:    * returned function value. 
                   1794:   */
1.126     brouard  1795:   int iter; 
                   1796:   double a,b,d,etemp;
1.159     brouard  1797:   double fu=0,fv,fw,fx;
1.164     brouard  1798:   double ftemp=0.;
1.126     brouard  1799:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1800:   double e=0.0; 
                   1801:  
                   1802:   a=(ax < cx ? ax : cx); 
                   1803:   b=(ax > cx ? ax : cx); 
                   1804:   x=w=v=bx; 
                   1805:   fw=fv=fx=(*f)(x); 
                   1806:   for (iter=1;iter<=ITMAX;iter++) { 
                   1807:     xm=0.5*(a+b); 
                   1808:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1809:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1810:     printf(".");fflush(stdout);
                   1811:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1812: #ifdef DEBUGBRENT
1.126     brouard  1813:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1814:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1815:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1816: #endif
                   1817:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1818:       *xmin=x; 
                   1819:       return fx; 
                   1820:     } 
                   1821:     ftemp=fu;
                   1822:     if (fabs(e) > tol1) { 
                   1823:       r=(x-w)*(fx-fv); 
                   1824:       q=(x-v)*(fx-fw); 
                   1825:       p=(x-v)*q-(x-w)*r; 
                   1826:       q=2.0*(q-r); 
                   1827:       if (q > 0.0) p = -p; 
                   1828:       q=fabs(q); 
                   1829:       etemp=e; 
                   1830:       e=d; 
                   1831:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1832:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1833:       else { 
1.224     brouard  1834:                                d=p/q; 
                   1835:                                u=x+d; 
                   1836:                                if (u-a < tol2 || b-u < tol2) 
                   1837:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1838:       } 
                   1839:     } else { 
                   1840:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1841:     } 
                   1842:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1843:     fu=(*f)(u); 
                   1844:     if (fu <= fx) { 
                   1845:       if (u >= x) a=x; else b=x; 
                   1846:       SHFT(v,w,x,u) 
1.183     brouard  1847:       SHFT(fv,fw,fx,fu) 
                   1848:     } else { 
                   1849:       if (u < x) a=u; else b=u; 
                   1850:       if (fu <= fw || w == x) { 
1.224     brouard  1851:                                v=w; 
                   1852:                                w=u; 
                   1853:                                fv=fw; 
                   1854:                                fw=fu; 
1.183     brouard  1855:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1856:                                v=u; 
                   1857:                                fv=fu; 
1.183     brouard  1858:       } 
                   1859:     } 
1.126     brouard  1860:   } 
                   1861:   nrerror("Too many iterations in brent"); 
                   1862:   *xmin=x; 
                   1863:   return fx; 
                   1864: } 
                   1865: 
                   1866: /****************** mnbrak ***********************/
                   1867: 
                   1868: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1869:            double (*func)(double)) 
1.183     brouard  1870: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1871: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1872: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1873: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1874:    */
1.126     brouard  1875:   double ulim,u,r,q, dum;
                   1876:   double fu; 
1.187     brouard  1877: 
                   1878:   double scale=10.;
                   1879:   int iterscale=0;
                   1880: 
                   1881:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1882:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1883: 
                   1884: 
                   1885:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1886:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1887:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1888:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1889:   /* } */
                   1890: 
1.126     brouard  1891:   if (*fb > *fa) { 
                   1892:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1893:     SHFT(dum,*fb,*fa,dum) 
                   1894:   } 
1.126     brouard  1895:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1896:   *fc=(*func)(*cx); 
1.183     brouard  1897: #ifdef DEBUG
1.224     brouard  1898:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1899:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1900: #endif
1.224     brouard  1901:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1902:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1903:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1904:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1905:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1906:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1907:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1908:       fu=(*func)(u); 
1.163     brouard  1909: #ifdef DEBUG
                   1910:       /* f(x)=A(x-u)**2+f(u) */
                   1911:       double A, fparabu; 
                   1912:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1913:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1914:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1915:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1916:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1917:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1918:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1919:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1920: #endif 
1.184     brouard  1921: #ifdef MNBRAKORIGINAL
1.183     brouard  1922: #else
1.191     brouard  1923: /*       if (fu > *fc) { */
                   1924: /* #ifdef DEBUG */
                   1925: /*       printf("mnbrak4  fu > fc \n"); */
                   1926: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1927: /* #endif */
                   1928: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1929: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1930: /*     dum=u; /\* Shifting c and u *\/ */
                   1931: /*     u = *cx; */
                   1932: /*     *cx = dum; */
                   1933: /*     dum = fu; */
                   1934: /*     fu = *fc; */
                   1935: /*     *fc =dum; */
                   1936: /*       } else { /\* end *\/ */
                   1937: /* #ifdef DEBUG */
                   1938: /*       printf("mnbrak3  fu < fc \n"); */
                   1939: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1940: /* #endif */
                   1941: /*     dum=u; /\* Shifting c and u *\/ */
                   1942: /*     u = *cx; */
                   1943: /*     *cx = dum; */
                   1944: /*     dum = fu; */
                   1945: /*     fu = *fc; */
                   1946: /*     *fc =dum; */
                   1947: /*       } */
1.224     brouard  1948: #ifdef DEBUGMNBRAK
                   1949:                 double A, fparabu; 
                   1950:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1951:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1952:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1953:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1954: #endif
1.191     brouard  1955:       dum=u; /* Shifting c and u */
                   1956:       u = *cx;
                   1957:       *cx = dum;
                   1958:       dum = fu;
                   1959:       fu = *fc;
                   1960:       *fc =dum;
1.183     brouard  1961: #endif
1.162     brouard  1962:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1963: #ifdef DEBUG
1.224     brouard  1964:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1965:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1966: #endif
1.126     brouard  1967:       fu=(*func)(u); 
                   1968:       if (fu < *fc) { 
1.183     brouard  1969: #ifdef DEBUG
1.224     brouard  1970:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1971:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1972: #endif
                   1973:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1974:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1975: #ifdef DEBUG
                   1976:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1977: #endif
                   1978:       } 
1.162     brouard  1979:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1980: #ifdef DEBUG
1.224     brouard  1981:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1982:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1983: #endif
1.126     brouard  1984:       u=ulim; 
                   1985:       fu=(*func)(u); 
1.183     brouard  1986:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1987: #ifdef DEBUG
1.224     brouard  1988:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1989:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1990: #endif
1.126     brouard  1991:       u=(*cx)+GOLD*(*cx-*bx); 
                   1992:       fu=(*func)(u); 
1.224     brouard  1993: #ifdef DEBUG
                   1994:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1995:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1996: #endif
1.183     brouard  1997:     } /* end tests */
1.126     brouard  1998:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1999:     SHFT(*fa,*fb,*fc,fu) 
                   2000: #ifdef DEBUG
1.224     brouard  2001:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2002:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2003: #endif
                   2004:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2005: } 
                   2006: 
                   2007: /*************** linmin ************************/
1.162     brouard  2008: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2009: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2010: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2011: the value of func at the returned location p . This is actually all accomplished by calling the
                   2012: routines mnbrak and brent .*/
1.126     brouard  2013: int ncom; 
                   2014: double *pcom,*xicom;
                   2015: double (*nrfunc)(double []); 
                   2016:  
1.224     brouard  2017: #ifdef LINMINORIGINAL
1.126     brouard  2018: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2019: #else
                   2020: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2021: #endif
1.126     brouard  2022: { 
                   2023:   double brent(double ax, double bx, double cx, 
                   2024:               double (*f)(double), double tol, double *xmin); 
                   2025:   double f1dim(double x); 
                   2026:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2027:              double *fc, double (*func)(double)); 
                   2028:   int j; 
                   2029:   double xx,xmin,bx,ax; 
                   2030:   double fx,fb,fa;
1.187     brouard  2031: 
1.203     brouard  2032: #ifdef LINMINORIGINAL
                   2033: #else
                   2034:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2035: #endif
                   2036:   
1.126     brouard  2037:   ncom=n; 
                   2038:   pcom=vector(1,n); 
                   2039:   xicom=vector(1,n); 
                   2040:   nrfunc=func; 
                   2041:   for (j=1;j<=n;j++) { 
                   2042:     pcom[j]=p[j]; 
1.202     brouard  2043:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2044:   } 
1.187     brouard  2045: 
1.203     brouard  2046: #ifdef LINMINORIGINAL
                   2047:   xx=1.;
                   2048: #else
                   2049:   axs=0.0;
                   2050:   xxs=1.;
                   2051:   do{
                   2052:     xx= xxs;
                   2053: #endif
1.187     brouard  2054:     ax=0.;
                   2055:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2056:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2057:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2058:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2059:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2060:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2061:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2062: #ifdef LINMINORIGINAL
                   2063: #else
                   2064:     if (fx != fx){
1.224     brouard  2065:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2066:                        printf("|");
                   2067:                        fprintf(ficlog,"|");
1.203     brouard  2068: #ifdef DEBUGLINMIN
1.224     brouard  2069:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2070: #endif
                   2071:     }
1.224     brouard  2072:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2073: #endif
                   2074:   
1.191     brouard  2075: #ifdef DEBUGLINMIN
                   2076:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2077:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2078: #endif
1.224     brouard  2079: #ifdef LINMINORIGINAL
                   2080: #else
                   2081:        if(fb == fx){ /* Flat function in the direction */
                   2082:                xmin=xx;
                   2083:     *flat=1;
                   2084:        }else{
                   2085:     *flat=0;
                   2086: #endif
                   2087:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2088:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2089:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2090:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2091:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2092:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2093: #ifdef DEBUG
1.224     brouard  2094:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2095:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2096: #endif
                   2097: #ifdef LINMINORIGINAL
                   2098: #else
                   2099:                        }
1.126     brouard  2100: #endif
1.191     brouard  2101: #ifdef DEBUGLINMIN
                   2102:   printf("linmin end ");
1.202     brouard  2103:   fprintf(ficlog,"linmin end ");
1.191     brouard  2104: #endif
1.126     brouard  2105:   for (j=1;j<=n;j++) { 
1.203     brouard  2106: #ifdef LINMINORIGINAL
                   2107:     xi[j] *= xmin; 
                   2108: #else
                   2109: #ifdef DEBUGLINMIN
                   2110:     if(xxs <1.0)
                   2111:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2112: #endif
                   2113:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2114: #ifdef DEBUGLINMIN
                   2115:     if(xxs <1.0)
                   2116:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2117: #endif
                   2118: #endif
1.187     brouard  2119:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2120:   } 
1.191     brouard  2121: #ifdef DEBUGLINMIN
1.203     brouard  2122:   printf("\n");
1.191     brouard  2123:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2124:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2125:   for (j=1;j<=n;j++) { 
1.202     brouard  2126:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2127:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2128:     if(j % ncovmodel == 0){
1.191     brouard  2129:       printf("\n");
1.202     brouard  2130:       fprintf(ficlog,"\n");
                   2131:     }
1.191     brouard  2132:   }
1.203     brouard  2133: #else
1.191     brouard  2134: #endif
1.126     brouard  2135:   free_vector(xicom,1,n); 
                   2136:   free_vector(pcom,1,n); 
                   2137: } 
                   2138: 
                   2139: 
                   2140: /*************** powell ************************/
1.162     brouard  2141: /*
                   2142: Minimization of a function func of n variables. Input consists of an initial starting point
                   2143: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2144: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2145: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2146: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2147: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2148:  */
1.224     brouard  2149: #ifdef LINMINORIGINAL
                   2150: #else
                   2151:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2152:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2153: #endif
1.126     brouard  2154: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2155:            double (*func)(double [])) 
                   2156: { 
1.224     brouard  2157: #ifdef LINMINORIGINAL
                   2158:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2159:              double (*func)(double [])); 
1.224     brouard  2160: #else 
1.241     brouard  2161:  void linmin(double p[], double xi[], int n, double *fret,
                   2162:             double (*func)(double []),int *flat); 
1.224     brouard  2163: #endif
1.239     brouard  2164:  int i,ibig,j,jk,k; 
1.126     brouard  2165:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2166:   double directest;
1.126     brouard  2167:   double fp,fptt;
                   2168:   double *xits;
                   2169:   int niterf, itmp;
1.224     brouard  2170: #ifdef LINMINORIGINAL
                   2171: #else
                   2172: 
                   2173:   flatdir=ivector(1,n); 
                   2174:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2175: #endif
1.126     brouard  2176: 
                   2177:   pt=vector(1,n); 
                   2178:   ptt=vector(1,n); 
                   2179:   xit=vector(1,n); 
                   2180:   xits=vector(1,n); 
                   2181:   *fret=(*func)(p); 
                   2182:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2183:   rcurr_time = time(NULL);  
1.126     brouard  2184:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2185:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2186:     ibig=0; 
                   2187:     del=0.0; 
1.157     brouard  2188:     rlast_time=rcurr_time;
                   2189:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2190:     rcurr_time = time(NULL);  
                   2191:     curr_time = *localtime(&rcurr_time);
                   2192:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2193:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2194: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2195:     for (i=1;i<=n;i++) {
1.126     brouard  2196:       fprintf(ficrespow," %.12lf", p[i]);
                   2197:     }
1.239     brouard  2198:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2199:     printf("\n#model=  1      +     age ");
                   2200:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2201:     if(nagesqr==1){
1.241     brouard  2202:        printf("  + age*age  ");
                   2203:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2204:     }
                   2205:     for(j=1;j <=ncovmodel-2;j++){
                   2206:       if(Typevar[j]==0) {
                   2207:        printf("  +      V%d  ",Tvar[j]);
                   2208:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2209:       }else if(Typevar[j]==1) {
                   2210:        printf("  +    V%d*age ",Tvar[j]);
                   2211:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2212:       }else if(Typevar[j]==2) {
                   2213:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2214:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2215:       }
                   2216:     }
1.126     brouard  2217:     printf("\n");
1.239     brouard  2218: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2219: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2220:     fprintf(ficlog,"\n");
1.239     brouard  2221:     for(i=1,jk=1; i <=nlstate; i++){
                   2222:       for(k=1; k <=(nlstate+ndeath); k++){
                   2223:        if (k != i) {
                   2224:          printf("%d%d ",i,k);
                   2225:          fprintf(ficlog,"%d%d ",i,k);
                   2226:          for(j=1; j <=ncovmodel; j++){
                   2227:            printf("%12.7f ",p[jk]);
                   2228:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2229:            jk++; 
                   2230:          }
                   2231:          printf("\n");
                   2232:          fprintf(ficlog,"\n");
                   2233:        }
                   2234:       }
                   2235:     }
1.241     brouard  2236:     if(*iter <=3 && *iter >1){
1.157     brouard  2237:       tml = *localtime(&rcurr_time);
                   2238:       strcpy(strcurr,asctime(&tml));
                   2239:       rforecast_time=rcurr_time; 
1.126     brouard  2240:       itmp = strlen(strcurr);
                   2241:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2242:        strcurr[itmp-1]='\0';
1.162     brouard  2243:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2244:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2245:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2246:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2247:        forecast_time = *localtime(&rforecast_time);
                   2248:        strcpy(strfor,asctime(&forecast_time));
                   2249:        itmp = strlen(strfor);
                   2250:        if(strfor[itmp-1]=='\n')
                   2251:          strfor[itmp-1]='\0';
                   2252:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2253:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2254:       }
                   2255:     }
1.187     brouard  2256:     for (i=1;i<=n;i++) { /* For each direction i */
                   2257:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2258:       fptt=(*fret); 
                   2259: #ifdef DEBUG
1.203     brouard  2260:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2261:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2262: #endif
1.203     brouard  2263:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2264:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2265: #ifdef LINMINORIGINAL
1.188     brouard  2266:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2267: #else
                   2268:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2269:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2270: #endif
                   2271:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2272:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2273:                                /* because that direction will be replaced unless the gain del is small */
                   2274:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2275:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2276:                                /* with the new direction. */
                   2277:                                del=fabs(fptt-(*fret)); 
                   2278:                                ibig=i; 
1.126     brouard  2279:       } 
                   2280: #ifdef DEBUG
                   2281:       printf("%d %.12e",i,(*fret));
                   2282:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2283:       for (j=1;j<=n;j++) {
1.224     brouard  2284:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2285:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2286:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2287:       }
                   2288:       for(j=1;j<=n;j++) {
1.225     brouard  2289:                                printf(" p(%d)=%.12e",j,p[j]);
                   2290:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2291:       }
                   2292:       printf("\n");
                   2293:       fprintf(ficlog,"\n");
                   2294: #endif
1.187     brouard  2295:     } /* end loop on each direction i */
                   2296:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2297:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2298:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2299:       for(j=1;j<=n;j++) {
1.225     brouard  2300:                                if(flatdir[j] >0){
                   2301:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2302:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2303:                                }
                   2304:                                /* printf("\n"); */
                   2305:                                /* fprintf(ficlog,"\n"); */
                   2306:                        }
1.243     brouard  2307:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2308:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2309:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2310:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2311:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2312:       /* decreased of more than 3.84  */
                   2313:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2314:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2315:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2316:                        
1.188     brouard  2317:       /* Starting the program with initial values given by a former maximization will simply change */
                   2318:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2319:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2320:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2321: #ifdef DEBUG
                   2322:       int k[2],l;
                   2323:       k[0]=1;
                   2324:       k[1]=-1;
                   2325:       printf("Max: %.12e",(*func)(p));
                   2326:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2327:       for (j=1;j<=n;j++) {
                   2328:        printf(" %.12e",p[j]);
                   2329:        fprintf(ficlog," %.12e",p[j]);
                   2330:       }
                   2331:       printf("\n");
                   2332:       fprintf(ficlog,"\n");
                   2333:       for(l=0;l<=1;l++) {
                   2334:        for (j=1;j<=n;j++) {
                   2335:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2336:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2337:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2338:        }
                   2339:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2340:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2341:       }
                   2342: #endif
                   2343: 
1.224     brouard  2344: #ifdef LINMINORIGINAL
                   2345: #else
                   2346:       free_ivector(flatdir,1,n); 
                   2347: #endif
1.126     brouard  2348:       free_vector(xit,1,n); 
                   2349:       free_vector(xits,1,n); 
                   2350:       free_vector(ptt,1,n); 
                   2351:       free_vector(pt,1,n); 
                   2352:       return; 
1.192     brouard  2353:     } /* enough precision */ 
1.240     brouard  2354:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2355:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2356:       ptt[j]=2.0*p[j]-pt[j]; 
                   2357:       xit[j]=p[j]-pt[j]; 
                   2358:       pt[j]=p[j]; 
                   2359:     } 
1.181     brouard  2360:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2361: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2362:                if (*iter <=4) {
1.225     brouard  2363: #else
                   2364: #endif
1.224     brouard  2365: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2366: #else
1.161     brouard  2367:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2368: #endif
1.162     brouard  2369:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2370:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2371:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2372:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2373:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2374:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2375:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2376:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2377:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2378:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2379:       /* mu² and del² are equal when f3=f1 */
                   2380:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2381:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2382:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2383:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2384: #ifdef NRCORIGINAL
                   2385:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2386: #else
                   2387:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2388:       t= t- del*SQR(fp-fptt);
1.183     brouard  2389: #endif
1.202     brouard  2390:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2391: #ifdef DEBUG
1.181     brouard  2392:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2393:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2394:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2395:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2396:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2397:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2398:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2399:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2400: #endif
1.183     brouard  2401: #ifdef POWELLORIGINAL
                   2402:       if (t < 0.0) { /* Then we use it for new direction */
                   2403: #else
1.182     brouard  2404:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2405:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2406:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2407:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2408:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2409:       } 
1.181     brouard  2410:       if (directest < 0.0) { /* Then we use it for new direction */
                   2411: #endif
1.191     brouard  2412: #ifdef DEBUGLINMIN
1.234     brouard  2413:        printf("Before linmin in direction P%d-P0\n",n);
                   2414:        for (j=1;j<=n;j++) {
                   2415:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2416:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2417:          if(j % ncovmodel == 0){
                   2418:            printf("\n");
                   2419:            fprintf(ficlog,"\n");
                   2420:          }
                   2421:        }
1.224     brouard  2422: #endif
                   2423: #ifdef LINMINORIGINAL
1.234     brouard  2424:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2425: #else
1.234     brouard  2426:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2427:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2428: #endif
1.234     brouard  2429:        
1.191     brouard  2430: #ifdef DEBUGLINMIN
1.234     brouard  2431:        for (j=1;j<=n;j++) { 
                   2432:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2433:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2434:          if(j % ncovmodel == 0){
                   2435:            printf("\n");
                   2436:            fprintf(ficlog,"\n");
                   2437:          }
                   2438:        }
1.224     brouard  2439: #endif
1.234     brouard  2440:        for (j=1;j<=n;j++) { 
                   2441:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2442:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2443:        }
1.224     brouard  2444: #ifdef LINMINORIGINAL
                   2445: #else
1.234     brouard  2446:        for (j=1, flatd=0;j<=n;j++) {
                   2447:          if(flatdir[j]>0)
                   2448:            flatd++;
                   2449:        }
                   2450:        if(flatd >0){
1.255     brouard  2451:          printf("%d flat directions: ",flatd);
                   2452:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2453:          for (j=1;j<=n;j++) { 
                   2454:            if(flatdir[j]>0){
                   2455:              printf("%d ",j);
                   2456:              fprintf(ficlog,"%d ",j);
                   2457:            }
                   2458:          }
                   2459:          printf("\n");
                   2460:          fprintf(ficlog,"\n");
                   2461:        }
1.191     brouard  2462: #endif
1.234     brouard  2463:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2464:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2465:        
1.126     brouard  2466: #ifdef DEBUG
1.234     brouard  2467:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2468:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2469:        for(j=1;j<=n;j++){
                   2470:          printf(" %lf",xit[j]);
                   2471:          fprintf(ficlog," %lf",xit[j]);
                   2472:        }
                   2473:        printf("\n");
                   2474:        fprintf(ficlog,"\n");
1.126     brouard  2475: #endif
1.192     brouard  2476:       } /* end of t or directest negative */
1.224     brouard  2477: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2478: #else
1.234     brouard  2479:       } /* end if (fptt < fp)  */
1.192     brouard  2480: #endif
1.225     brouard  2481: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2482:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2483: #else
1.224     brouard  2484: #endif
1.234     brouard  2485:                } /* loop iteration */ 
1.126     brouard  2486: } 
1.234     brouard  2487:   
1.126     brouard  2488: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2489:   
1.235     brouard  2490:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2491:   {
1.235     brouard  2492:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2493:        (and selected quantitative values in nres)
                   2494:        by left multiplying the unit
1.234     brouard  2495:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2496:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2497:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2498:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2499:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2500:   /* Initial matrix pimij */
                   2501:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2502:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2503:   /*  0,                   0                  , 1} */
                   2504:   /*
                   2505:    * and after some iteration: */
                   2506:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2507:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2508:   /*  0,                   0                  , 1} */
                   2509:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2510:   /* {0.51571254859325999, 0.4842874514067399, */
                   2511:   /*  0.51326036147820708, 0.48673963852179264} */
                   2512:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2513:     
1.126     brouard  2514:   int i, ii,j,k;
1.209     brouard  2515:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2516:   /* double **matprod2(); */ /* test */
1.218     brouard  2517:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2518:   double **newm;
1.209     brouard  2519:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2520:   int ncvloop=0;
1.169     brouard  2521:   
1.209     brouard  2522:   min=vector(1,nlstate);
                   2523:   max=vector(1,nlstate);
                   2524:   meandiff=vector(1,nlstate);
                   2525: 
1.218     brouard  2526:        /* Starting with matrix unity */
1.126     brouard  2527:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2528:     for (j=1;j<=nlstate+ndeath;j++){
                   2529:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2530:     }
1.169     brouard  2531:   
                   2532:   cov[1]=1.;
                   2533:   
                   2534:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2535:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2536:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2537:     ncvloop++;
1.126     brouard  2538:     newm=savm;
                   2539:     /* Covariates have to be included here again */
1.138     brouard  2540:     cov[2]=agefin;
1.187     brouard  2541:     if(nagesqr==1)
                   2542:       cov[3]= agefin*agefin;;
1.234     brouard  2543:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2544:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2545:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2546:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2547:     }
                   2548:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2549:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2550:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2551:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2552:     }
1.237     brouard  2553:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2554:       if(Dummy[Tvar[Tage[k]]]){
                   2555:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2556:       } else{
1.235     brouard  2557:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2558:       }
1.235     brouard  2559:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2560:     }
1.237     brouard  2561:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2562:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2563:       if(Dummy[Tvard[k][1]==0]){
                   2564:        if(Dummy[Tvard[k][2]==0]){
                   2565:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2566:        }else{
                   2567:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2568:        }
                   2569:       }else{
                   2570:        if(Dummy[Tvard[k][2]==0]){
                   2571:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2572:        }else{
                   2573:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2574:        }
                   2575:       }
1.234     brouard  2576:     }
1.138     brouard  2577:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2578:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2579:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2580:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2581:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2582:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2583:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2584:     
1.126     brouard  2585:     savm=oldm;
                   2586:     oldm=newm;
1.209     brouard  2587: 
                   2588:     for(j=1; j<=nlstate; j++){
                   2589:       max[j]=0.;
                   2590:       min[j]=1.;
                   2591:     }
                   2592:     for(i=1;i<=nlstate;i++){
                   2593:       sumnew=0;
                   2594:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2595:       for(j=1; j<=nlstate; j++){ 
                   2596:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2597:        max[j]=FMAX(max[j],prlim[i][j]);
                   2598:        min[j]=FMIN(min[j],prlim[i][j]);
                   2599:       }
                   2600:     }
                   2601: 
1.126     brouard  2602:     maxmax=0.;
1.209     brouard  2603:     for(j=1; j<=nlstate; j++){
                   2604:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2605:       maxmax=FMAX(maxmax,meandiff[j]);
                   2606:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2607:     } /* j loop */
1.203     brouard  2608:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2609:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2610:     if(maxmax < ftolpl){
1.209     brouard  2611:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2612:       free_vector(min,1,nlstate);
                   2613:       free_vector(max,1,nlstate);
                   2614:       free_vector(meandiff,1,nlstate);
1.126     brouard  2615:       return prlim;
                   2616:     }
1.169     brouard  2617:   } /* age loop */
1.208     brouard  2618:     /* After some age loop it doesn't converge */
1.209     brouard  2619:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2620: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2621:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2622:   free_vector(min,1,nlstate);
                   2623:   free_vector(max,1,nlstate);
                   2624:   free_vector(meandiff,1,nlstate);
1.208     brouard  2625:   
1.169     brouard  2626:   return prlim; /* should not reach here */
1.126     brouard  2627: }
                   2628: 
1.217     brouard  2629: 
                   2630:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2631: 
1.218     brouard  2632:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2633:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2634:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2635: {
1.264     brouard  2636:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2637:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2638:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2639:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2640:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2641:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2642:   /* Initial matrix pimij */
                   2643:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2644:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2645:   /*  0,                   0                  , 1} */
                   2646:   /*
                   2647:    * and after some iteration: */
                   2648:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2649:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2650:   /*  0,                   0                  , 1} */
                   2651:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2652:   /* {0.51571254859325999, 0.4842874514067399, */
                   2653:   /*  0.51326036147820708, 0.48673963852179264} */
                   2654:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2655: 
                   2656:   int i, ii,j,k;
1.247     brouard  2657:   int first=0;
1.217     brouard  2658:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2659:   /* double **matprod2(); */ /* test */
                   2660:   double **out, cov[NCOVMAX+1], **bmij();
                   2661:   double **newm;
1.218     brouard  2662:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2663:   double        **oldm, **savm;  /* for use */
                   2664: 
1.217     brouard  2665:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2666:   int ncvloop=0;
                   2667:   
                   2668:   min=vector(1,nlstate);
                   2669:   max=vector(1,nlstate);
                   2670:   meandiff=vector(1,nlstate);
                   2671: 
1.266     brouard  2672:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2673:   oldm=oldms; savm=savms;
                   2674:   
                   2675:   /* Starting with matrix unity */
                   2676:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2677:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2678:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2679:     }
                   2680:   
                   2681:   cov[1]=1.;
                   2682:   
                   2683:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2684:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2685:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2686:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2687:     ncvloop++;
1.218     brouard  2688:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2689:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2690:     /* Covariates have to be included here again */
                   2691:     cov[2]=agefin;
                   2692:     if(nagesqr==1)
                   2693:       cov[3]= agefin*agefin;;
1.242     brouard  2694:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2695:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2696:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2697:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2698:     }
                   2699:     /* for (k=1; k<=cptcovn;k++) { */
                   2700:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2701:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2702:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2703:     /* } */
                   2704:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2705:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2706:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2707:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2708:     }
                   2709:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2710:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2711:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2712:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2713:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2714:       if(Dummy[Tvar[Tage[k]]]){
                   2715:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2716:       } else{
                   2717:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2718:       }
                   2719:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2720:     }
                   2721:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2722:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2723:       if(Dummy[Tvard[k][1]==0]){
                   2724:        if(Dummy[Tvard[k][2]==0]){
                   2725:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2726:        }else{
                   2727:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2728:        }
                   2729:       }else{
                   2730:        if(Dummy[Tvard[k][2]==0]){
                   2731:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2732:        }else{
                   2733:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2734:        }
                   2735:       }
1.217     brouard  2736:     }
                   2737:     
                   2738:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2739:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2740:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2741:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2742:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2743:                /* ij should be linked to the correct index of cov */
                   2744:                /* age and covariate values ij are in 'cov', but we need to pass
                   2745:                 * ij for the observed prevalence at age and status and covariate
                   2746:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2747:                 */
                   2748:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2749:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2750:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2751:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2752:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2753:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2754:     /*         printf("%d newm= ",i); */
                   2755:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2756:     /*           printf("%f ",newm[i][j]); */
                   2757:     /*         } */
                   2758:     /*         printf("oldm * "); */
                   2759:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2760:     /*           printf("%f ",oldm[i][j]); */
                   2761:     /*         } */
1.268     brouard  2762:     /*         printf(" bmmij "); */
1.266     brouard  2763:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2764:     /*           printf("%f ",pmmij[i][j]); */
                   2765:     /*         } */
                   2766:     /*         printf("\n"); */
                   2767:     /*   } */
                   2768:     /* } */
1.217     brouard  2769:     savm=oldm;
                   2770:     oldm=newm;
1.266     brouard  2771: 
1.217     brouard  2772:     for(j=1; j<=nlstate; j++){
                   2773:       max[j]=0.;
                   2774:       min[j]=1.;
                   2775:     }
                   2776:     for(j=1; j<=nlstate; j++){ 
                   2777:       for(i=1;i<=nlstate;i++){
1.234     brouard  2778:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2779:        bprlim[i][j]= newm[i][j];
                   2780:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2781:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2782:       }
                   2783:     }
1.218     brouard  2784:                
1.217     brouard  2785:     maxmax=0.;
                   2786:     for(i=1; i<=nlstate; i++){
                   2787:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2788:       maxmax=FMAX(maxmax,meandiff[i]);
                   2789:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2790:     } /* i loop */
1.217     brouard  2791:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2792:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2793:     if(maxmax < ftolpl){
1.220     brouard  2794:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2795:       free_vector(min,1,nlstate);
                   2796:       free_vector(max,1,nlstate);
                   2797:       free_vector(meandiff,1,nlstate);
                   2798:       return bprlim;
                   2799:     }
                   2800:   } /* age loop */
                   2801:     /* After some age loop it doesn't converge */
1.247     brouard  2802:   if(first){
                   2803:     first=1;
                   2804:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2805: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2806:   }
                   2807:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2808: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2809:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2810:   free_vector(min,1,nlstate);
                   2811:   free_vector(max,1,nlstate);
                   2812:   free_vector(meandiff,1,nlstate);
                   2813:   
                   2814:   return bprlim; /* should not reach here */
                   2815: }
                   2816: 
1.126     brouard  2817: /*************** transition probabilities ***************/ 
                   2818: 
                   2819: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2820: {
1.138     brouard  2821:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2822:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2823:      model to the ncovmodel covariates (including constant and age).
                   2824:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2825:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2826:      ncth covariate in the global vector x is given by the formula:
                   2827:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2828:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2829:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2830:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2831:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2832:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2833:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2834:   */
                   2835:   double s1, lnpijopii;
1.126     brouard  2836:   /*double t34;*/
1.164     brouard  2837:   int i,j, nc, ii, jj;
1.126     brouard  2838: 
1.223     brouard  2839:   for(i=1; i<= nlstate; i++){
                   2840:     for(j=1; j<i;j++){
                   2841:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2842:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2843:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2844:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2845:       }
                   2846:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2847:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2848:     }
                   2849:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2850:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2851:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2852:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2853:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2854:       }
                   2855:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2856:     }
                   2857:   }
1.218     brouard  2858:   
1.223     brouard  2859:   for(i=1; i<= nlstate; i++){
                   2860:     s1=0;
                   2861:     for(j=1; j<i; j++){
                   2862:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2863:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2864:     }
                   2865:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2866:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2867:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2868:     }
                   2869:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2870:     ps[i][i]=1./(s1+1.);
                   2871:     /* Computing other pijs */
                   2872:     for(j=1; j<i; j++)
                   2873:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2874:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2875:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2876:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2877:   } /* end i */
1.218     brouard  2878:   
1.223     brouard  2879:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2880:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2881:       ps[ii][jj]=0;
                   2882:       ps[ii][ii]=1;
                   2883:     }
                   2884:   }
1.218     brouard  2885:   
                   2886:   
1.223     brouard  2887:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2888:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2889:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2890:   /*   } */
                   2891:   /*   printf("\n "); */
                   2892:   /* } */
                   2893:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2894:   /*
                   2895:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2896:                goto end;*/
1.266     brouard  2897:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2898: }
                   2899: 
1.218     brouard  2900: /*************** backward transition probabilities ***************/ 
                   2901: 
                   2902:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2903: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2904:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2905: {
1.266     brouard  2906:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2907:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2908:    */
1.218     brouard  2909:   int i, ii, j,k;
1.222     brouard  2910:   
                   2911:   double **out, **pmij();
                   2912:   double sumnew=0.;
1.218     brouard  2913:   double agefin;
1.268     brouard  2914:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2915:   double **dnewm, **dsavm, **doldm;
                   2916:   double **bbmij;
                   2917:   
1.218     brouard  2918:   doldm=ddoldms; /* global pointers */
1.222     brouard  2919:   dnewm=ddnewms;
                   2920:   dsavm=ddsavms;
                   2921:   
                   2922:   agefin=cov[2];
1.268     brouard  2923:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2924:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2925:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2926:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2927: 
                   2928:   /* P_x */
1.266     brouard  2929:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2930:   /* outputs pmmij which is a stochastic matrix in row */
                   2931: 
                   2932:   /* Diag(w_x) */
                   2933:   /* Problem with prevacurrent which can be zero */
                   2934:   sumnew=0.;
1.269     brouard  2935:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2936:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2937:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2938:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2939:   }
                   2940:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2941:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2942:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2943:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2944:     }
                   2945:   }else{
                   2946:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2947:       for (j=1;j<=nlstate+ndeath;j++)
                   2948:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2949:     }
                   2950:     /* if(sumnew <0.9){ */
                   2951:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2952:     /* } */
                   2953:   }
                   2954:   k3=0.0;  /* We put the last diagonal to 0 */
                   2955:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2956:       doldm[ii][ii]= k3;
                   2957:   }
                   2958:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2959:   
                   2960:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2961:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2962: 
                   2963:   /* Diag(Sum_i w^i_x p^ij_x */
                   2964:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2965:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2966:     sumnew=0.;
1.222     brouard  2967:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2968:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2969:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2970:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2971:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2972:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2973:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2974:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2975:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2976:        /* }else */
1.268     brouard  2977:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2978:     } /*End ii */
                   2979:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2980: 
                   2981:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2982:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2983:   /* end bmij */
1.266     brouard  2984:   return ps; /*pointer is unchanged */
1.218     brouard  2985: }
1.217     brouard  2986: /*************** transition probabilities ***************/ 
                   2987: 
1.218     brouard  2988: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2989: {
                   2990:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2991:      computes the probability to be observed in state j being in state i by appying the
                   2992:      model to the ncovmodel covariates (including constant and age).
                   2993:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2994:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2995:      ncth covariate in the global vector x is given by the formula:
                   2996:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2997:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2998:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2999:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3000:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3001:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3002:   */
                   3003:   double s1, lnpijopii;
                   3004:   /*double t34;*/
                   3005:   int i,j, nc, ii, jj;
                   3006: 
1.234     brouard  3007:   for(i=1; i<= nlstate; i++){
                   3008:     for(j=1; j<i;j++){
                   3009:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3010:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3011:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3012:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3013:       }
                   3014:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3015:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3016:     }
                   3017:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3018:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3019:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3020:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3021:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3022:       }
                   3023:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3024:     }
                   3025:   }
                   3026:   
                   3027:   for(i=1; i<= nlstate; i++){
                   3028:     s1=0;
                   3029:     for(j=1; j<i; j++){
                   3030:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3031:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3032:     }
                   3033:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3034:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3035:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3036:     }
                   3037:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3038:     ps[i][i]=1./(s1+1.);
                   3039:     /* Computing other pijs */
                   3040:     for(j=1; j<i; j++)
                   3041:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3042:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3043:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3044:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3045:   } /* end i */
                   3046:   
                   3047:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3048:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3049:       ps[ii][jj]=0;
                   3050:       ps[ii][ii]=1;
                   3051:     }
                   3052:   }
                   3053:   /* Added for backcast */ /* Transposed matrix too */
                   3054:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3055:     s1=0.;
                   3056:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3057:       s1+=ps[ii][jj];
                   3058:     }
                   3059:     for(ii=1; ii<= nlstate; ii++){
                   3060:       ps[ii][jj]=ps[ii][jj]/s1;
                   3061:     }
                   3062:   }
                   3063:   /* Transposition */
                   3064:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3065:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3066:       s1=ps[ii][jj];
                   3067:       ps[ii][jj]=ps[jj][ii];
                   3068:       ps[jj][ii]=s1;
                   3069:     }
                   3070:   }
                   3071:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3072:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3073:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3074:   /*   } */
                   3075:   /*   printf("\n "); */
                   3076:   /* } */
                   3077:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3078:   /*
                   3079:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3080:     goto end;*/
                   3081:   return ps;
1.217     brouard  3082: }
                   3083: 
                   3084: 
1.126     brouard  3085: /**************** Product of 2 matrices ******************/
                   3086: 
1.145     brouard  3087: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3088: {
                   3089:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3090:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3091:   /* in, b, out are matrice of pointers which should have been initialized 
                   3092:      before: only the contents of out is modified. The function returns
                   3093:      a pointer to pointers identical to out */
1.145     brouard  3094:   int i, j, k;
1.126     brouard  3095:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3096:     for(k=ncolol; k<=ncoloh; k++){
                   3097:       out[i][k]=0.;
                   3098:       for(j=ncl; j<=nch; j++)
                   3099:        out[i][k] +=in[i][j]*b[j][k];
                   3100:     }
1.126     brouard  3101:   return out;
                   3102: }
                   3103: 
                   3104: 
                   3105: /************* Higher Matrix Product ***************/
                   3106: 
1.235     brouard  3107: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3108: {
1.218     brouard  3109:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3110:      'nhstepm*hstepm*stepm' months (i.e. until
                   3111:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3112:      nhstepm*hstepm matrices. 
                   3113:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3114:      (typically every 2 years instead of every month which is too big 
                   3115:      for the memory).
                   3116:      Model is determined by parameters x and covariates have to be 
                   3117:      included manually here. 
                   3118: 
                   3119:      */
                   3120: 
                   3121:   int i, j, d, h, k;
1.131     brouard  3122:   double **out, cov[NCOVMAX+1];
1.126     brouard  3123:   double **newm;
1.187     brouard  3124:   double agexact;
1.214     brouard  3125:   double agebegin, ageend;
1.126     brouard  3126: 
                   3127:   /* Hstepm could be zero and should return the unit matrix */
                   3128:   for (i=1;i<=nlstate+ndeath;i++)
                   3129:     for (j=1;j<=nlstate+ndeath;j++){
                   3130:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3131:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3132:     }
                   3133:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3134:   for(h=1; h <=nhstepm; h++){
                   3135:     for(d=1; d <=hstepm; d++){
                   3136:       newm=savm;
                   3137:       /* Covariates have to be included here again */
                   3138:       cov[1]=1.;
1.214     brouard  3139:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3140:       cov[2]=agexact;
                   3141:       if(nagesqr==1)
1.227     brouard  3142:        cov[3]= agexact*agexact;
1.235     brouard  3143:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3144:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3145:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3146:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3147:       }
                   3148:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3149:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3150:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3151:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3152:       }
                   3153:       for (k=1; k<=cptcovage;k++){
                   3154:        if(Dummy[Tvar[Tage[k]]]){
                   3155:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3156:        } else{
                   3157:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3158:        }
                   3159:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3160:       }
                   3161:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3162:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3163:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3164:       }
                   3165:       /* for (k=1; k<=cptcovn;k++)  */
                   3166:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3167:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3168:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3169:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3170:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3171:       
                   3172:       
1.126     brouard  3173:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3174:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3175:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3176:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3177:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3178:       /* if((int)age == 70){ */
                   3179:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3180:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3181:       /*         printf("%d pmmij ",i); */
                   3182:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3183:       /*           printf("%f ",pmmij[i][j]); */
                   3184:       /*         } */
                   3185:       /*         printf(" oldm "); */
                   3186:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3187:       /*           printf("%f ",oldm[i][j]); */
                   3188:       /*         } */
                   3189:       /*         printf("\n"); */
                   3190:       /*       } */
                   3191:       /* } */
1.126     brouard  3192:       savm=oldm;
                   3193:       oldm=newm;
                   3194:     }
                   3195:     for(i=1; i<=nlstate+ndeath; i++)
                   3196:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3197:        po[i][j][h]=newm[i][j];
                   3198:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3199:       }
1.128     brouard  3200:     /*printf("h=%d ",h);*/
1.126     brouard  3201:   } /* end h */
1.267     brouard  3202:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3203:   return po;
                   3204: }
                   3205: 
1.217     brouard  3206: /************* Higher Back Matrix Product ***************/
1.218     brouard  3207: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3208: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3209: {
1.266     brouard  3210:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3211:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3212:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3213:      nhstepm*hstepm matrices.
                   3214:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3215:      (typically every 2 years instead of every month which is too big
1.217     brouard  3216:      for the memory).
1.218     brouard  3217:      Model is determined by parameters x and covariates have to be
1.266     brouard  3218:      included manually here. Then we use a call to bmij(x and cov)
                   3219:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3220:   */
1.217     brouard  3221: 
                   3222:   int i, j, d, h, k;
1.266     brouard  3223:   double **out, cov[NCOVMAX+1], **bmij();
                   3224:   double **newm, ***newmm;
1.217     brouard  3225:   double agexact;
                   3226:   double agebegin, ageend;
1.222     brouard  3227:   double **oldm, **savm;
1.217     brouard  3228: 
1.266     brouard  3229:   newmm=po; /* To be saved */
                   3230:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3231:   /* Hstepm could be zero and should return the unit matrix */
                   3232:   for (i=1;i<=nlstate+ndeath;i++)
                   3233:     for (j=1;j<=nlstate+ndeath;j++){
                   3234:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3235:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3236:     }
                   3237:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3238:   for(h=1; h <=nhstepm; h++){
                   3239:     for(d=1; d <=hstepm; d++){
                   3240:       newm=savm;
                   3241:       /* Covariates have to be included here again */
                   3242:       cov[1]=1.;
1.266     brouard  3243:       agexact=age-((h-1)*hstepm + (d))*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3244:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3245:       cov[2]=agexact;
                   3246:       if(nagesqr==1)
1.222     brouard  3247:        cov[3]= agexact*agexact;
1.266     brouard  3248:       for (k=1; k<=cptcovn;k++){
                   3249:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3250:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3251:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3252:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3253:       }
1.267     brouard  3254:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3255:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3256:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3257:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3258:       }
                   3259:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3260:        if(Dummy[Tvar[Tage[k]]]){
                   3261:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3262:        } else{
                   3263:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3264:        }
                   3265:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3266:       }
                   3267:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3268:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3269:       }                        
1.217     brouard  3270:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3271:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3272: 
1.218     brouard  3273:       /* Careful transposed matrix */
1.266     brouard  3274:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3275:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3276:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3277:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3278:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3279:       /* if((int)age == 70){ */
                   3280:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3281:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3282:       /*         printf("%d pmmij ",i); */
                   3283:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3284:       /*           printf("%f ",pmmij[i][j]); */
                   3285:       /*         } */
                   3286:       /*         printf(" oldm "); */
                   3287:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3288:       /*           printf("%f ",oldm[i][j]); */
                   3289:       /*         } */
                   3290:       /*         printf("\n"); */
                   3291:       /*       } */
                   3292:       /* } */
                   3293:       savm=oldm;
                   3294:       oldm=newm;
                   3295:     }
                   3296:     for(i=1; i<=nlstate+ndeath; i++)
                   3297:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3298:        po[i][j][h]=newm[i][j];
1.268     brouard  3299:        /* if(h==nhstepm) */
                   3300:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3301:       }
1.268     brouard  3302:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3303:   } /* end h */
1.268     brouard  3304:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3305:   return po;
                   3306: }
                   3307: 
                   3308: 
1.162     brouard  3309: #ifdef NLOPT
                   3310:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3311:   double fret;
                   3312:   double *xt;
                   3313:   int j;
                   3314:   myfunc_data *d2 = (myfunc_data *) pd;
                   3315: /* xt = (p1-1); */
                   3316:   xt=vector(1,n); 
                   3317:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3318: 
                   3319:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3320:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3321:   printf("Function = %.12lf ",fret);
                   3322:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3323:   printf("\n");
                   3324:  free_vector(xt,1,n);
                   3325:   return fret;
                   3326: }
                   3327: #endif
1.126     brouard  3328: 
                   3329: /*************** log-likelihood *************/
                   3330: double func( double *x)
                   3331: {
1.226     brouard  3332:   int i, ii, j, k, mi, d, kk;
                   3333:   int ioffset=0;
                   3334:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3335:   double **out;
                   3336:   double lli; /* Individual log likelihood */
                   3337:   int s1, s2;
1.228     brouard  3338:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3339:   double bbh, survp;
                   3340:   long ipmx;
                   3341:   double agexact;
                   3342:   /*extern weight */
                   3343:   /* We are differentiating ll according to initial status */
                   3344:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3345:   /*for(i=1;i<imx;i++) 
                   3346:     printf(" %d\n",s[4][i]);
                   3347:   */
1.162     brouard  3348: 
1.226     brouard  3349:   ++countcallfunc;
1.162     brouard  3350: 
1.226     brouard  3351:   cov[1]=1.;
1.126     brouard  3352: 
1.226     brouard  3353:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3354:   ioffset=0;
1.226     brouard  3355:   if(mle==1){
                   3356:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3357:       /* Computes the values of the ncovmodel covariates of the model
                   3358:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3359:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3360:         to be observed in j being in i according to the model.
                   3361:       */
1.243     brouard  3362:       ioffset=2+nagesqr ;
1.233     brouard  3363:    /* Fixed */
1.234     brouard  3364:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3365:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3366:       }
1.226     brouard  3367:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3368:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3369:         has been calculated etc */
                   3370:       /* For an individual i, wav[i] gives the number of effective waves */
                   3371:       /* We compute the contribution to Likelihood of each effective transition
                   3372:         mw[mi][i] is real wave of the mi th effectve wave */
                   3373:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3374:         s2=s[mw[mi+1][i]][i];
                   3375:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3376:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3377:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3378:       */
                   3379:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3380:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3381:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3382:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3383:        }
                   3384:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3385:          for (j=1;j<=nlstate+ndeath;j++){
                   3386:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3387:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3388:          }
                   3389:        for(d=0; d<dh[mi][i]; d++){
                   3390:          newm=savm;
                   3391:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3392:          cov[2]=agexact;
                   3393:          if(nagesqr==1)
                   3394:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3395:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3396:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3397:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3398:          else
                   3399:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3400:          }
                   3401:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3402:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3403:          savm=oldm;
                   3404:          oldm=newm;
                   3405:        } /* end mult */
                   3406:        
                   3407:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3408:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3409:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3410:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3411:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3412:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3413:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3414:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3415:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3416:                                 * -stepm/2 to stepm/2 .
                   3417:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3418:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3419:                                 */
1.234     brouard  3420:        s1=s[mw[mi][i]][i];
                   3421:        s2=s[mw[mi+1][i]][i];
                   3422:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3423:        /* bias bh is positive if real duration
                   3424:         * is higher than the multiple of stepm and negative otherwise.
                   3425:         */
                   3426:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3427:        if( s2 > nlstate){ 
                   3428:          /* i.e. if s2 is a death state and if the date of death is known 
                   3429:             then the contribution to the likelihood is the probability to 
                   3430:             die between last step unit time and current  step unit time, 
                   3431:             which is also equal to probability to die before dh 
                   3432:             minus probability to die before dh-stepm . 
                   3433:             In version up to 0.92 likelihood was computed
                   3434:             as if date of death was unknown. Death was treated as any other
                   3435:             health state: the date of the interview describes the actual state
                   3436:             and not the date of a change in health state. The former idea was
                   3437:             to consider that at each interview the state was recorded
                   3438:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3439:             introduced the exact date of death then we should have modified
                   3440:             the contribution of an exact death to the likelihood. This new
                   3441:             contribution is smaller and very dependent of the step unit
                   3442:             stepm. It is no more the probability to die between last interview
                   3443:             and month of death but the probability to survive from last
                   3444:             interview up to one month before death multiplied by the
                   3445:             probability to die within a month. Thanks to Chris
                   3446:             Jackson for correcting this bug.  Former versions increased
                   3447:             mortality artificially. The bad side is that we add another loop
                   3448:             which slows down the processing. The difference can be up to 10%
                   3449:             lower mortality.
                   3450:          */
                   3451:          /* If, at the beginning of the maximization mostly, the
                   3452:             cumulative probability or probability to be dead is
                   3453:             constant (ie = 1) over time d, the difference is equal to
                   3454:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3455:             s1 at precedent wave, to be dead a month before current
                   3456:             wave is equal to probability, being at state s1 at
                   3457:             precedent wave, to be dead at mont of the current
                   3458:             wave. Then the observed probability (that this person died)
                   3459:             is null according to current estimated parameter. In fact,
                   3460:             it should be very low but not zero otherwise the log go to
                   3461:             infinity.
                   3462:          */
1.183     brouard  3463: /* #ifdef INFINITYORIGINAL */
                   3464: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3465: /* #else */
                   3466: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3467: /*         lli=log(mytinydouble); */
                   3468: /*       else */
                   3469: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3470: /* #endif */
1.226     brouard  3471:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3472:          
1.226     brouard  3473:        } else if  ( s2==-1 ) { /* alive */
                   3474:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3475:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3476:          /*survp += out[s1][j]; */
                   3477:          lli= log(survp);
                   3478:        }
                   3479:        else if  (s2==-4) { 
                   3480:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3481:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3482:          lli= log(survp); 
                   3483:        } 
                   3484:        else if  (s2==-5) { 
                   3485:          for (j=1,survp=0. ; j<=2; j++)  
                   3486:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3487:          lli= log(survp); 
                   3488:        } 
                   3489:        else{
                   3490:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3491:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3492:        } 
                   3493:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3494:        /*if(lli ==000.0)*/
                   3495:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3496:        ipmx +=1;
                   3497:        sw += weight[i];
                   3498:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3499:        /* if (lli < log(mytinydouble)){ */
                   3500:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3501:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3502:        /* } */
                   3503:       } /* end of wave */
                   3504:     } /* end of individual */
                   3505:   }  else if(mle==2){
                   3506:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3507:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3508:       for(mi=1; mi<= wav[i]-1; mi++){
                   3509:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3510:          for (j=1;j<=nlstate+ndeath;j++){
                   3511:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3512:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3513:          }
                   3514:        for(d=0; d<=dh[mi][i]; d++){
                   3515:          newm=savm;
                   3516:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3517:          cov[2]=agexact;
                   3518:          if(nagesqr==1)
                   3519:            cov[3]= agexact*agexact;
                   3520:          for (kk=1; kk<=cptcovage;kk++) {
                   3521:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3522:          }
                   3523:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3524:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3525:          savm=oldm;
                   3526:          oldm=newm;
                   3527:        } /* end mult */
                   3528:       
                   3529:        s1=s[mw[mi][i]][i];
                   3530:        s2=s[mw[mi+1][i]][i];
                   3531:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3532:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3533:        ipmx +=1;
                   3534:        sw += weight[i];
                   3535:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3536:       } /* end of wave */
                   3537:     } /* end of individual */
                   3538:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3539:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3540:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3541:       for(mi=1; mi<= wav[i]-1; mi++){
                   3542:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3543:          for (j=1;j<=nlstate+ndeath;j++){
                   3544:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3545:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3546:          }
                   3547:        for(d=0; d<dh[mi][i]; d++){
                   3548:          newm=savm;
                   3549:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3550:          cov[2]=agexact;
                   3551:          if(nagesqr==1)
                   3552:            cov[3]= agexact*agexact;
                   3553:          for (kk=1; kk<=cptcovage;kk++) {
                   3554:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3555:          }
                   3556:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3557:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3558:          savm=oldm;
                   3559:          oldm=newm;
                   3560:        } /* end mult */
                   3561:       
                   3562:        s1=s[mw[mi][i]][i];
                   3563:        s2=s[mw[mi+1][i]][i];
                   3564:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3565:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3566:        ipmx +=1;
                   3567:        sw += weight[i];
                   3568:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3569:       } /* end of wave */
                   3570:     } /* end of individual */
                   3571:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3572:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3573:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3574:       for(mi=1; mi<= wav[i]-1; mi++){
                   3575:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3576:          for (j=1;j<=nlstate+ndeath;j++){
                   3577:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3578:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3579:          }
                   3580:        for(d=0; d<dh[mi][i]; d++){
                   3581:          newm=savm;
                   3582:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3583:          cov[2]=agexact;
                   3584:          if(nagesqr==1)
                   3585:            cov[3]= agexact*agexact;
                   3586:          for (kk=1; kk<=cptcovage;kk++) {
                   3587:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3588:          }
1.126     brouard  3589:        
1.226     brouard  3590:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3591:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3592:          savm=oldm;
                   3593:          oldm=newm;
                   3594:        } /* end mult */
                   3595:       
                   3596:        s1=s[mw[mi][i]][i];
                   3597:        s2=s[mw[mi+1][i]][i];
                   3598:        if( s2 > nlstate){ 
                   3599:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3600:        } else if  ( s2==-1 ) { /* alive */
                   3601:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3602:            survp += out[s1][j];
                   3603:          lli= log(survp);
                   3604:        }else{
                   3605:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3606:        }
                   3607:        ipmx +=1;
                   3608:        sw += weight[i];
                   3609:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3610: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3611:       } /* end of wave */
                   3612:     } /* end of individual */
                   3613:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3614:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3615:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3616:       for(mi=1; mi<= wav[i]-1; mi++){
                   3617:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3618:          for (j=1;j<=nlstate+ndeath;j++){
                   3619:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3620:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3621:          }
                   3622:        for(d=0; d<dh[mi][i]; d++){
                   3623:          newm=savm;
                   3624:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3625:          cov[2]=agexact;
                   3626:          if(nagesqr==1)
                   3627:            cov[3]= agexact*agexact;
                   3628:          for (kk=1; kk<=cptcovage;kk++) {
                   3629:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3630:          }
1.126     brouard  3631:        
1.226     brouard  3632:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3633:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3634:          savm=oldm;
                   3635:          oldm=newm;
                   3636:        } /* end mult */
                   3637:       
                   3638:        s1=s[mw[mi][i]][i];
                   3639:        s2=s[mw[mi+1][i]][i];
                   3640:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3641:        ipmx +=1;
                   3642:        sw += weight[i];
                   3643:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3644:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3645:       } /* end of wave */
                   3646:     } /* end of individual */
                   3647:   } /* End of if */
                   3648:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3649:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3650:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3651:   return -l;
1.126     brouard  3652: }
                   3653: 
                   3654: /*************** log-likelihood *************/
                   3655: double funcone( double *x)
                   3656: {
1.228     brouard  3657:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3658:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3659:   int ioffset=0;
1.131     brouard  3660:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3661:   double **out;
                   3662:   double lli; /* Individual log likelihood */
                   3663:   double llt;
                   3664:   int s1, s2;
1.228     brouard  3665:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3666: 
1.126     brouard  3667:   double bbh, survp;
1.187     brouard  3668:   double agexact;
1.214     brouard  3669:   double agebegin, ageend;
1.126     brouard  3670:   /*extern weight */
                   3671:   /* We are differentiating ll according to initial status */
                   3672:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3673:   /*for(i=1;i<imx;i++) 
                   3674:     printf(" %d\n",s[4][i]);
                   3675:   */
                   3676:   cov[1]=1.;
                   3677: 
                   3678:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3679:   ioffset=0;
                   3680:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3681:     /* ioffset=2+nagesqr+cptcovage; */
                   3682:     ioffset=2+nagesqr;
1.232     brouard  3683:     /* Fixed */
1.224     brouard  3684:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3685:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3686:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3687:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3688: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3689: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3690: /*    cov[2+6]=covar[2][i]; V2  */
                   3691: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3692: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3693: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3694: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3695: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3696: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3697:     }
1.232     brouard  3698:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3699:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3700:     /* } */
1.231     brouard  3701:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3702:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3703:     /* } */
1.225     brouard  3704:     
1.233     brouard  3705: 
                   3706:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3707:     /* Wave varying (but not age varying) */
                   3708:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3709:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3710:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3711:       }
1.232     brouard  3712:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3713:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3714:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3715:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3716:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3717:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3718:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3719:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3720:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3721:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3722:       /* } */
1.126     brouard  3723:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3724:        for (j=1;j<=nlstate+ndeath;j++){
                   3725:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3726:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3727:        }
1.214     brouard  3728:       
                   3729:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3730:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3731:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3732:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3733:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3734:          and mw[mi+1][i]. dh depends on stepm.*/
                   3735:        newm=savm;
1.247     brouard  3736:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3737:        cov[2]=agexact;
                   3738:        if(nagesqr==1)
                   3739:          cov[3]= agexact*agexact;
                   3740:        for (kk=1; kk<=cptcovage;kk++) {
                   3741:          if(!FixedV[Tvar[Tage[kk]]])
                   3742:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3743:          else
                   3744:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3745:        }
                   3746:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3747:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3748:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3749:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3750:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3751:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3752:        savm=oldm;
                   3753:        oldm=newm;
1.126     brouard  3754:       } /* end mult */
                   3755:       
                   3756:       s1=s[mw[mi][i]][i];
                   3757:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3758:       /* if(s2==-1){ */
1.268     brouard  3759:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3760:       /*       /\* exit(1); *\/ */
                   3761:       /* } */
1.126     brouard  3762:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3763:       /* bias is positive if real duration
                   3764:        * is higher than the multiple of stepm and negative otherwise.
                   3765:        */
                   3766:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3767:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3768:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3769:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3770:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3771:        lli= log(survp);
1.126     brouard  3772:       }else if (mle==1){
1.242     brouard  3773:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3774:       } else if(mle==2){
1.242     brouard  3775:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3776:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3777:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3778:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3779:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3780:       } else{  /* mle=0 back to 1 */
1.242     brouard  3781:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3782:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3783:       } /* End of if */
                   3784:       ipmx +=1;
                   3785:       sw += weight[i];
                   3786:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3787:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3788:       if(globpr){
1.246     brouard  3789:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3790:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3791:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3792:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3793:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3794:          llt +=ll[k]*gipmx/gsw;
                   3795:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3796:        }
                   3797:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3798:       }
1.232     brouard  3799:        } /* end of wave */
                   3800: } /* end of individual */
                   3801: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3802: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3803: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3804: if(globpr==0){ /* First time we count the contributions and weights */
                   3805:        gipmx=ipmx;
                   3806:        gsw=sw;
                   3807: }
                   3808: return -l;
1.126     brouard  3809: }
                   3810: 
                   3811: 
                   3812: /*************** function likelione ***********/
                   3813: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3814: {
                   3815:   /* This routine should help understanding what is done with 
                   3816:      the selection of individuals/waves and
                   3817:      to check the exact contribution to the likelihood.
                   3818:      Plotting could be done.
                   3819:    */
                   3820:   int k;
                   3821: 
                   3822:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3823:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3824:     strcat(fileresilk,fileresu);
1.126     brouard  3825:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3826:       printf("Problem with resultfile: %s\n", fileresilk);
                   3827:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3828:     }
1.214     brouard  3829:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3830:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3831:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3832:     for(k=1; k<=nlstate; k++) 
                   3833:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3834:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3835:   }
                   3836: 
                   3837:   *fretone=(*funcone)(p);
                   3838:   if(*globpri !=0){
                   3839:     fclose(ficresilk);
1.205     brouard  3840:     if (mle ==0)
                   3841:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3842:     else if(mle >=1)
                   3843:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3844:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3845:     
1.208     brouard  3846:       
                   3847:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3848:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3849: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3850:     }
1.207     brouard  3851:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3852: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3853:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3854: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3855:     fflush(fichtm);
1.205     brouard  3856:   }
1.126     brouard  3857:   return;
                   3858: }
                   3859: 
                   3860: 
                   3861: /*********** Maximum Likelihood Estimation ***************/
                   3862: 
                   3863: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3864: {
1.165     brouard  3865:   int i,j, iter=0;
1.126     brouard  3866:   double **xi;
                   3867:   double fret;
                   3868:   double fretone; /* Only one call to likelihood */
                   3869:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3870: 
                   3871: #ifdef NLOPT
                   3872:   int creturn;
                   3873:   nlopt_opt opt;
                   3874:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3875:   double *lb;
                   3876:   double minf; /* the minimum objective value, upon return */
                   3877:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3878:   myfunc_data dinst, *d = &dinst;
                   3879: #endif
                   3880: 
                   3881: 
1.126     brouard  3882:   xi=matrix(1,npar,1,npar);
                   3883:   for (i=1;i<=npar;i++)
                   3884:     for (j=1;j<=npar;j++)
                   3885:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3886:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3887:   strcpy(filerespow,"POW_"); 
1.126     brouard  3888:   strcat(filerespow,fileres);
                   3889:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3890:     printf("Problem with resultfile: %s\n", filerespow);
                   3891:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3892:   }
                   3893:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3894:   for (i=1;i<=nlstate;i++)
                   3895:     for(j=1;j<=nlstate+ndeath;j++)
                   3896:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3897:   fprintf(ficrespow,"\n");
1.162     brouard  3898: #ifdef POWELL
1.126     brouard  3899:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3900: #endif
1.126     brouard  3901: 
1.162     brouard  3902: #ifdef NLOPT
                   3903: #ifdef NEWUOA
                   3904:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3905: #else
                   3906:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3907: #endif
                   3908:   lb=vector(0,npar-1);
                   3909:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3910:   nlopt_set_lower_bounds(opt, lb);
                   3911:   nlopt_set_initial_step1(opt, 0.1);
                   3912:   
                   3913:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3914:   d->function = func;
                   3915:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3916:   nlopt_set_min_objective(opt, myfunc, d);
                   3917:   nlopt_set_xtol_rel(opt, ftol);
                   3918:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3919:     printf("nlopt failed! %d\n",creturn); 
                   3920:   }
                   3921:   else {
                   3922:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3923:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3924:     iter=1; /* not equal */
                   3925:   }
                   3926:   nlopt_destroy(opt);
                   3927: #endif
1.126     brouard  3928:   free_matrix(xi,1,npar,1,npar);
                   3929:   fclose(ficrespow);
1.203     brouard  3930:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3931:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3932:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3933: 
                   3934: }
                   3935: 
                   3936: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3937: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3938: {
                   3939:   double  **a,**y,*x,pd;
1.203     brouard  3940:   /* double **hess; */
1.164     brouard  3941:   int i, j;
1.126     brouard  3942:   int *indx;
                   3943: 
                   3944:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3945:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3946:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3947:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3948:   double gompertz(double p[]);
1.203     brouard  3949:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3950: 
                   3951:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3952:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3953:   for (i=1;i<=npar;i++){
1.203     brouard  3954:     printf("%d-",i);fflush(stdout);
                   3955:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3956:    
                   3957:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3958:     
                   3959:     /*  printf(" %f ",p[i]);
                   3960:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3961:   }
                   3962:   
                   3963:   for (i=1;i<=npar;i++) {
                   3964:     for (j=1;j<=npar;j++)  {
                   3965:       if (j>i) { 
1.203     brouard  3966:        printf(".%d-%d",i,j);fflush(stdout);
                   3967:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3968:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3969:        
                   3970:        hess[j][i]=hess[i][j];    
                   3971:        /*printf(" %lf ",hess[i][j]);*/
                   3972:       }
                   3973:     }
                   3974:   }
                   3975:   printf("\n");
                   3976:   fprintf(ficlog,"\n");
                   3977: 
                   3978:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3979:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3980:   
                   3981:   a=matrix(1,npar,1,npar);
                   3982:   y=matrix(1,npar,1,npar);
                   3983:   x=vector(1,npar);
                   3984:   indx=ivector(1,npar);
                   3985:   for (i=1;i<=npar;i++)
                   3986:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3987:   ludcmp(a,npar,indx,&pd);
                   3988: 
                   3989:   for (j=1;j<=npar;j++) {
                   3990:     for (i=1;i<=npar;i++) x[i]=0;
                   3991:     x[j]=1;
                   3992:     lubksb(a,npar,indx,x);
                   3993:     for (i=1;i<=npar;i++){ 
                   3994:       matcov[i][j]=x[i];
                   3995:     }
                   3996:   }
                   3997: 
                   3998:   printf("\n#Hessian matrix#\n");
                   3999:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4000:   for (i=1;i<=npar;i++) { 
                   4001:     for (j=1;j<=npar;j++) { 
1.203     brouard  4002:       printf("%.6e ",hess[i][j]);
                   4003:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4004:     }
                   4005:     printf("\n");
                   4006:     fprintf(ficlog,"\n");
                   4007:   }
                   4008: 
1.203     brouard  4009:   /* printf("\n#Covariance matrix#\n"); */
                   4010:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4011:   /* for (i=1;i<=npar;i++) {  */
                   4012:   /*   for (j=1;j<=npar;j++) {  */
                   4013:   /*     printf("%.6e ",matcov[i][j]); */
                   4014:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4015:   /*   } */
                   4016:   /*   printf("\n"); */
                   4017:   /*   fprintf(ficlog,"\n"); */
                   4018:   /* } */
                   4019: 
1.126     brouard  4020:   /* Recompute Inverse */
1.203     brouard  4021:   /* for (i=1;i<=npar;i++) */
                   4022:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4023:   /* ludcmp(a,npar,indx,&pd); */
                   4024: 
                   4025:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4026: 
                   4027:   /* for (j=1;j<=npar;j++) { */
                   4028:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4029:   /*   x[j]=1; */
                   4030:   /*   lubksb(a,npar,indx,x); */
                   4031:   /*   for (i=1;i<=npar;i++){  */
                   4032:   /*     y[i][j]=x[i]; */
                   4033:   /*     printf("%.3e ",y[i][j]); */
                   4034:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4035:   /*   } */
                   4036:   /*   printf("\n"); */
                   4037:   /*   fprintf(ficlog,"\n"); */
                   4038:   /* } */
                   4039: 
                   4040:   /* Verifying the inverse matrix */
                   4041: #ifdef DEBUGHESS
                   4042:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4043: 
1.203     brouard  4044:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4045:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4046: 
                   4047:   for (j=1;j<=npar;j++) {
                   4048:     for (i=1;i<=npar;i++){ 
1.203     brouard  4049:       printf("%.2f ",y[i][j]);
                   4050:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4051:     }
                   4052:     printf("\n");
                   4053:     fprintf(ficlog,"\n");
                   4054:   }
1.203     brouard  4055: #endif
1.126     brouard  4056: 
                   4057:   free_matrix(a,1,npar,1,npar);
                   4058:   free_matrix(y,1,npar,1,npar);
                   4059:   free_vector(x,1,npar);
                   4060:   free_ivector(indx,1,npar);
1.203     brouard  4061:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4062: 
                   4063: 
                   4064: }
                   4065: 
                   4066: /*************** hessian matrix ****************/
                   4067: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4068: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4069:   int i;
                   4070:   int l=1, lmax=20;
1.203     brouard  4071:   double k1,k2, res, fx;
1.132     brouard  4072:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4073:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4074:   int k=0,kmax=10;
                   4075:   double l1;
                   4076: 
                   4077:   fx=func(x);
                   4078:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4079:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4080:     l1=pow(10,l);
                   4081:     delts=delt;
                   4082:     for(k=1 ; k <kmax; k=k+1){
                   4083:       delt = delta*(l1*k);
                   4084:       p2[theta]=x[theta] +delt;
1.145     brouard  4085:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4086:       p2[theta]=x[theta]-delt;
                   4087:       k2=func(p2)-fx;
                   4088:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4089:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4090:       
1.203     brouard  4091: #ifdef DEBUGHESSII
1.126     brouard  4092:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4093:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4094: #endif
                   4095:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4096:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4097:        k=kmax;
                   4098:       }
                   4099:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4100:        k=kmax; l=lmax*10;
1.126     brouard  4101:       }
                   4102:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4103:        delts=delt;
                   4104:       }
1.203     brouard  4105:     } /* End loop k */
1.126     brouard  4106:   }
                   4107:   delti[theta]=delts;
                   4108:   return res; 
                   4109:   
                   4110: }
                   4111: 
1.203     brouard  4112: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4113: {
                   4114:   int i;
1.164     brouard  4115:   int l=1, lmax=20;
1.126     brouard  4116:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4117:   double p2[MAXPARM+1];
1.203     brouard  4118:   int k, kmax=1;
                   4119:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4120: 
                   4121:   int firstime=0;
1.203     brouard  4122:   
1.126     brouard  4123:   fx=func(x);
1.203     brouard  4124:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4125:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4126:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4127:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4128:     k1=func(p2)-fx;
                   4129:   
1.203     brouard  4130:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4131:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4132:     k2=func(p2)-fx;
                   4133:   
1.203     brouard  4134:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4135:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4136:     k3=func(p2)-fx;
                   4137:   
1.203     brouard  4138:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4139:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4140:     k4=func(p2)-fx;
1.203     brouard  4141:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4142:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4143:       firstime=1;
1.203     brouard  4144:       kmax=kmax+10;
1.208     brouard  4145:     }
                   4146:     if(kmax >=10 || firstime ==1){
1.246     brouard  4147:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4148:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4149:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4150:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4151:     }
                   4152: #ifdef DEBUGHESSIJ
                   4153:     v1=hess[thetai][thetai];
                   4154:     v2=hess[thetaj][thetaj];
                   4155:     cv12=res;
                   4156:     /* Computing eigen value of Hessian matrix */
                   4157:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4158:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4159:     if ((lc2 <0) || (lc1 <0) ){
                   4160:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4161:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4162:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4163:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4164:     }
1.126     brouard  4165: #endif
                   4166:   }
                   4167:   return res;
                   4168: }
                   4169: 
1.203     brouard  4170:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4171: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4172: /* { */
                   4173: /*   int i; */
                   4174: /*   int l=1, lmax=20; */
                   4175: /*   double k1,k2,k3,k4,res,fx; */
                   4176: /*   double p2[MAXPARM+1]; */
                   4177: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4178: /*   int k=0,kmax=10; */
                   4179: /*   double l1; */
                   4180:   
                   4181: /*   fx=func(x); */
                   4182: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4183: /*     l1=pow(10,l); */
                   4184: /*     delts=delt; */
                   4185: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4186: /*       delt = delti*(l1*k); */
                   4187: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4188: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4189: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4190: /*       k1=func(p2)-fx; */
                   4191:       
                   4192: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4193: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4194: /*       k2=func(p2)-fx; */
                   4195:       
                   4196: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4197: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4198: /*       k3=func(p2)-fx; */
                   4199:       
                   4200: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4201: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4202: /*       k4=func(p2)-fx; */
                   4203: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4204: /* #ifdef DEBUGHESSIJ */
                   4205: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4206: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4207: /* #endif */
                   4208: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4209: /*     k=kmax; */
                   4210: /*       } */
                   4211: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4212: /*     k=kmax; l=lmax*10; */
                   4213: /*       } */
                   4214: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4215: /*     delts=delt; */
                   4216: /*       } */
                   4217: /*     } /\* End loop k *\/ */
                   4218: /*   } */
                   4219: /*   delti[theta]=delts; */
                   4220: /*   return res;  */
                   4221: /* } */
                   4222: 
                   4223: 
1.126     brouard  4224: /************** Inverse of matrix **************/
                   4225: void ludcmp(double **a, int n, int *indx, double *d) 
                   4226: { 
                   4227:   int i,imax,j,k; 
                   4228:   double big,dum,sum,temp; 
                   4229:   double *vv; 
                   4230:  
                   4231:   vv=vector(1,n); 
                   4232:   *d=1.0; 
                   4233:   for (i=1;i<=n;i++) { 
                   4234:     big=0.0; 
                   4235:     for (j=1;j<=n;j++) 
                   4236:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4237:     if (big == 0.0){
                   4238:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4239:       for (j=1;j<=n;j++) {
                   4240:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4241:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4242:       }
                   4243:       fflush(ficlog);
                   4244:       fclose(ficlog);
                   4245:       nrerror("Singular matrix in routine ludcmp"); 
                   4246:     }
1.126     brouard  4247:     vv[i]=1.0/big; 
                   4248:   } 
                   4249:   for (j=1;j<=n;j++) { 
                   4250:     for (i=1;i<j;i++) { 
                   4251:       sum=a[i][j]; 
                   4252:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4253:       a[i][j]=sum; 
                   4254:     } 
                   4255:     big=0.0; 
                   4256:     for (i=j;i<=n;i++) { 
                   4257:       sum=a[i][j]; 
                   4258:       for (k=1;k<j;k++) 
                   4259:        sum -= a[i][k]*a[k][j]; 
                   4260:       a[i][j]=sum; 
                   4261:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4262:        big=dum; 
                   4263:        imax=i; 
                   4264:       } 
                   4265:     } 
                   4266:     if (j != imax) { 
                   4267:       for (k=1;k<=n;k++) { 
                   4268:        dum=a[imax][k]; 
                   4269:        a[imax][k]=a[j][k]; 
                   4270:        a[j][k]=dum; 
                   4271:       } 
                   4272:       *d = -(*d); 
                   4273:       vv[imax]=vv[j]; 
                   4274:     } 
                   4275:     indx[j]=imax; 
                   4276:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4277:     if (j != n) { 
                   4278:       dum=1.0/(a[j][j]); 
                   4279:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4280:     } 
                   4281:   } 
                   4282:   free_vector(vv,1,n);  /* Doesn't work */
                   4283: ;
                   4284: } 
                   4285: 
                   4286: void lubksb(double **a, int n, int *indx, double b[]) 
                   4287: { 
                   4288:   int i,ii=0,ip,j; 
                   4289:   double sum; 
                   4290:  
                   4291:   for (i=1;i<=n;i++) { 
                   4292:     ip=indx[i]; 
                   4293:     sum=b[ip]; 
                   4294:     b[ip]=b[i]; 
                   4295:     if (ii) 
                   4296:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4297:     else if (sum) ii=i; 
                   4298:     b[i]=sum; 
                   4299:   } 
                   4300:   for (i=n;i>=1;i--) { 
                   4301:     sum=b[i]; 
                   4302:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4303:     b[i]=sum/a[i][i]; 
                   4304:   } 
                   4305: } 
                   4306: 
                   4307: void pstamp(FILE *fichier)
                   4308: {
1.196     brouard  4309:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4310: }
                   4311: 
1.253     brouard  4312: 
                   4313: 
1.126     brouard  4314: /************ Frequencies ********************/
1.251     brouard  4315: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4316:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4317:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4318: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4319:   
1.265     brouard  4320:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4321:   int iind=0, iage=0;
                   4322:   int mi; /* Effective wave */
                   4323:   int first;
                   4324:   double ***freq; /* Frequencies */
1.268     brouard  4325:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4326:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4327:   double *meanq;
                   4328:   double **meanqt;
                   4329:   double *pp, **prop, *posprop, *pospropt;
                   4330:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4331:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4332:   double agebegin, ageend;
                   4333:     
                   4334:   pp=vector(1,nlstate);
1.251     brouard  4335:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4336:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4337:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4338:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4339:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4340:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4341:   strcpy(fileresp,"P_");
                   4342:   strcat(fileresp,fileresu);
                   4343:   /*strcat(fileresphtm,fileresu);*/
                   4344:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4345:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4346:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4347:     exit(0);
                   4348:   }
1.240     brouard  4349:   
1.226     brouard  4350:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4351:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4352:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4353:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4354:     fflush(ficlog);
                   4355:     exit(70); 
                   4356:   }
                   4357:   else{
                   4358:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4359: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4360: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4361:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4362:   }
1.237     brouard  4363:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4364:   
1.226     brouard  4365:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4366:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4367:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4368:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4369:     fflush(ficlog);
                   4370:     exit(70); 
1.240     brouard  4371:   } else{
1.226     brouard  4372:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4373: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4374: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4375:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4376:   }
1.240     brouard  4377:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4378:   
1.253     brouard  4379:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4380:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4381:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4382:   j1=0;
1.126     brouard  4383:   
1.227     brouard  4384:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4385:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4386:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4387:   
                   4388:   
1.226     brouard  4389:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4390:      reference=low_education V1=0,V2=0
                   4391:      med_educ                V1=1 V2=0, 
                   4392:      high_educ               V1=0 V2=1
                   4393:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4394:   */
1.249     brouard  4395:   dateintsum=0;
                   4396:   k2cpt=0;
                   4397: 
1.253     brouard  4398:   if(cptcoveff == 0 )
1.265     brouard  4399:     nl=1;  /* Constant and age model only */
1.253     brouard  4400:   else
                   4401:     nl=2;
1.265     brouard  4402: 
                   4403:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4404:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4405:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4406:    *     freq[s1][s2][iage] =0.
                   4407:    *     Loop on iind
                   4408:    *       ++freq[s1][s2][iage] weighted
                   4409:    *     end iind
                   4410:    *     if covariate and j!0
                   4411:    *       headers Variable on one line
                   4412:    *     endif cov j!=0
                   4413:    *     header of frequency table by age
                   4414:    *     Loop on age
                   4415:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4416:    *       pos+=freq[s1][s2][iage] weighted
                   4417:    *       Loop on s1 initial state
                   4418:    *         fprintf(ficresp
                   4419:    *       end s1
                   4420:    *     end age
                   4421:    *     if j!=0 computes starting values
                   4422:    *     end compute starting values
                   4423:    *   end j1
                   4424:    * end nl 
                   4425:    */
1.253     brouard  4426:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4427:     if(nj==1)
                   4428:       j=0;  /* First pass for the constant */
1.265     brouard  4429:     else{
1.253     brouard  4430:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4431:     }
1.251     brouard  4432:     first=1;
1.265     brouard  4433:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4434:       posproptt=0.;
                   4435:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4436:        scanf("%d", i);*/
                   4437:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4438:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4439:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4440:            freq[i][s2][m]=0;
1.251     brouard  4441:       
                   4442:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4443:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4444:          prop[i][m]=0;
                   4445:        posprop[i]=0;
                   4446:        pospropt[i]=0;
                   4447:       }
                   4448:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4449:       /*   meanq[z1]+=0.; */
                   4450:       /*   for(m=1;m<=lastpass;m++){ */
                   4451:       /*       meanqt[m][z1]=0.; */
                   4452:       /*   } */
                   4453:       /* } */
                   4454:       
                   4455:       /* dateintsum=0; */
                   4456:       /* k2cpt=0; */
                   4457:       
1.265     brouard  4458:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4459:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4460:        bool=1;
                   4461:        if(j !=0){
                   4462:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4463:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4464:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4465:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4466:              /* } */
                   4467:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4468:                /* if(Tvaraff[z1] ==-20){ */
                   4469:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4470:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4471:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4472:                /* }else  */
                   4473:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4474:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4475:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4476:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4477:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4478:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4479:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4480:                } /* Onlyf fixed */
                   4481:              } /* end z1 */
                   4482:            } /* cptcovn > 0 */
                   4483:          } /* end any */
                   4484:        }/* end j==0 */
1.265     brouard  4485:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4486:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4487:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4488:            m=mw[mi][iind];
                   4489:            if(j!=0){
                   4490:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4491:                for (z1=1; z1<=cptcoveff; z1++) {
                   4492:                  if( Fixed[Tmodelind[z1]]==1){
                   4493:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4494:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4495:                                                                                      value is -1, we don't select. It differs from the 
                   4496:                                                                                      constant and age model which counts them. */
                   4497:                      bool=0; /* not selected */
                   4498:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4499:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4500:                      bool=0;
                   4501:                    }
                   4502:                  }
                   4503:                }
                   4504:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4505:            } /* end j==0 */
                   4506:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4507:            if(bool==1){
                   4508:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4509:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4510:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4511:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4512:              if(m >=firstpass && m <=lastpass){
                   4513:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4514:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4515:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4516:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4517:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4518:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4519:                if (m<lastpass) {
                   4520:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4521:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4522:                  if(s[m][iind]==-1)
                   4523:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4524:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4525:                  /* if((int)agev[m][iind] == 55) */
                   4526:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4527:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4528:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4529:                }
1.251     brouard  4530:              } /* end if between passes */  
                   4531:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4532:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4533:                k2cpt++;
                   4534:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4535:              }
1.251     brouard  4536:            }else{
                   4537:              bool=1;
                   4538:            }/* end bool 2 */
                   4539:          } /* end m */
                   4540:        } /* end bool */
                   4541:       } /* end iind = 1 to imx */
                   4542:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4543:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4544:       
                   4545:       
                   4546:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4547:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4548:         pstamp(ficresp);
1.251     brouard  4549:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4550:         pstamp(ficresp);
1.251     brouard  4551:        printf( "\n#********** Variable "); 
                   4552:        fprintf(ficresp, "\n#********** Variable "); 
                   4553:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4554:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4555:        fprintf(ficlog, "\n#********** Variable "); 
                   4556:        for (z1=1; z1<=cptcoveff; z1++){
                   4557:          if(!FixedV[Tvaraff[z1]]){
                   4558:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4559:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4560:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4561:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4562:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4563:          }else{
1.251     brouard  4564:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4565:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4566:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4567:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4568:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4569:          }
                   4570:        }
                   4571:        printf( "**********\n#");
                   4572:        fprintf(ficresp, "**********\n#");
                   4573:        fprintf(ficresphtm, "**********</h3>\n");
                   4574:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4575:        fprintf(ficlog, "**********\n");
                   4576:       }
                   4577:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4578:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4579:         fprintf(ficresp, " Age");
                   4580:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4581:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4582:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4583:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4584:       }
1.265     brouard  4585:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4586:       fprintf(ficresphtm, "\n");
                   4587:       
                   4588:       /* Header of frequency table by age */
                   4589:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4590:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4591:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4592:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4593:          if(s2!=0 && m!=0)
                   4594:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4595:        }
1.226     brouard  4596:       }
1.251     brouard  4597:       fprintf(ficresphtmfr, "\n");
                   4598:     
                   4599:       /* For each age */
                   4600:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4601:        fprintf(ficresphtm,"<tr>");
                   4602:        if(iage==iagemax+1){
                   4603:          fprintf(ficlog,"1");
                   4604:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4605:        }else if(iage==iagemax+2){
                   4606:          fprintf(ficlog,"0");
                   4607:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4608:        }else if(iage==iagemax+3){
                   4609:          fprintf(ficlog,"Total");
                   4610:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4611:        }else{
1.240     brouard  4612:          if(first==1){
1.251     brouard  4613:            first=0;
                   4614:            printf("See log file for details...\n");
                   4615:          }
                   4616:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4617:          fprintf(ficlog,"Age %d", iage);
                   4618:        }
1.265     brouard  4619:        for(s1=1; s1 <=nlstate ; s1++){
                   4620:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4621:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4622:        }
1.265     brouard  4623:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4624:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4625:            pos += freq[s1][m][iage];
                   4626:          if(pp[s1]>=1.e-10){
1.251     brouard  4627:            if(first==1){
1.265     brouard  4628:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4629:            }
1.265     brouard  4630:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4631:          }else{
                   4632:            if(first==1)
1.265     brouard  4633:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4634:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4635:          }
                   4636:        }
                   4637:       
1.265     brouard  4638:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4639:          /* posprop[s1]=0; */
                   4640:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4641:            pp[s1] += freq[s1][m][iage];
                   4642:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4643:       
                   4644:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4645:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4646:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4647:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4648:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4649:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4650:        }
                   4651:        
                   4652:        /* Writing ficresp */
                   4653:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4654:           if( iage <= iagemax){
                   4655:            fprintf(ficresp," %d",iage);
                   4656:           }
                   4657:         }else if( nj==2){
                   4658:           if( iage <= iagemax){
                   4659:            fprintf(ficresp," %d",iage);
                   4660:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4661:           }
1.240     brouard  4662:        }
1.265     brouard  4663:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4664:          if(pos>=1.e-5){
1.251     brouard  4665:            if(first==1)
1.265     brouard  4666:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4667:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4668:          }else{
                   4669:            if(first==1)
1.265     brouard  4670:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4671:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4672:          }
                   4673:          if( iage <= iagemax){
                   4674:            if(pos>=1.e-5){
1.265     brouard  4675:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4676:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4677:               }else if( nj==2){
                   4678:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4679:               }
                   4680:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4681:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4682:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4683:            } else{
                   4684:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4685:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4686:            }
1.240     brouard  4687:          }
1.265     brouard  4688:          pospropt[s1] +=posprop[s1];
                   4689:        } /* end loop s1 */
1.251     brouard  4690:        /* pospropt=0.; */
1.265     brouard  4691:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4692:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4693:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4694:              if(first==1){
1.265     brouard  4695:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4696:              }
1.265     brouard  4697:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4698:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4699:            }
1.265     brouard  4700:            if(s1!=0 && m!=0)
                   4701:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4702:          }
1.265     brouard  4703:        } /* end loop s1 */
1.251     brouard  4704:        posproptt=0.; 
1.265     brouard  4705:        for(s1=1; s1 <=nlstate; s1++){
                   4706:          posproptt += pospropt[s1];
1.251     brouard  4707:        }
                   4708:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4709:        fprintf(ficresphtm,"</tr>\n");
                   4710:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4711:          if(iage <= iagemax)
                   4712:            fprintf(ficresp,"\n");
1.240     brouard  4713:        }
1.251     brouard  4714:        if(first==1)
                   4715:          printf("Others in log...\n");
                   4716:        fprintf(ficlog,"\n");
                   4717:       } /* end loop age iage */
1.265     brouard  4718:       
1.251     brouard  4719:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4720:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4721:        if(posproptt < 1.e-5){
1.265     brouard  4722:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4723:        }else{
1.265     brouard  4724:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4725:        }
1.226     brouard  4726:       }
1.251     brouard  4727:       fprintf(ficresphtm,"</tr>\n");
                   4728:       fprintf(ficresphtm,"</table>\n");
                   4729:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4730:       if(posproptt < 1.e-5){
1.251     brouard  4731:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4732:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4733:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4734:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4735:        invalidvarcomb[j1]=1;
1.226     brouard  4736:       }else{
1.251     brouard  4737:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4738:        invalidvarcomb[j1]=0;
1.226     brouard  4739:       }
1.251     brouard  4740:       fprintf(ficresphtmfr,"</table>\n");
                   4741:       fprintf(ficlog,"\n");
                   4742:       if(j!=0){
                   4743:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4744:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4745:          for(k=1; k <=(nlstate+ndeath); k++){
                   4746:            if (k != i) {
1.265     brouard  4747:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4748:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4749:                  if(j1==1){ /* All dummy covariates to zero */
                   4750:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4751:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4752:                    printf("%d%d ",i,k);
                   4753:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4754:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4755:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4756:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4757:                  }
1.253     brouard  4758:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4759:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4760:                    x[iage]= (double)iage;
                   4761:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4762:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4763:                  }
1.268     brouard  4764:                  /* Some are not finite, but linreg will ignore these ages */
                   4765:                  no=0;
1.253     brouard  4766:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4767:                  pstart[s1]=b;
                   4768:                  pstart[s1-1]=a;
1.252     brouard  4769:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4770:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4771:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4772:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4773:                  printf("%d%d ",i,k);
                   4774:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4775:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4776:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4777:                  ;
                   4778:                }
                   4779:                /* printf("%12.7f )", param[i][jj][k]); */
                   4780:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4781:                s1++; 
1.251     brouard  4782:              } /* end jj */
                   4783:            } /* end k!= i */
                   4784:          } /* end k */
1.265     brouard  4785:        } /* end i, s1 */
1.251     brouard  4786:       } /* end j !=0 */
                   4787:     } /* end selected combination of covariate j1 */
                   4788:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4789:       printf("#Freqsummary: Starting values for the constants:\n");
                   4790:       fprintf(ficlog,"\n");
1.265     brouard  4791:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4792:        for(k=1; k <=(nlstate+ndeath); k++){
                   4793:          if (k != i) {
                   4794:            printf("%d%d ",i,k);
                   4795:            fprintf(ficlog,"%d%d ",i,k);
                   4796:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4797:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4798:              if(jj==1){ /* Age has to be done */
1.265     brouard  4799:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4800:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4801:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4802:              }
                   4803:              /* printf("%12.7f )", param[i][jj][k]); */
                   4804:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4805:              s1++; 
1.250     brouard  4806:            }
1.251     brouard  4807:            printf("\n");
                   4808:            fprintf(ficlog,"\n");
1.250     brouard  4809:          }
                   4810:        }
                   4811:       }
1.251     brouard  4812:       printf("#Freqsummary\n");
                   4813:       fprintf(ficlog,"\n");
1.265     brouard  4814:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4815:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4816:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4817:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4818:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4819:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4820:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4821:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4822:          /* } */
                   4823:        }
1.265     brouard  4824:       } /* end loop s1 */
1.251     brouard  4825:       
                   4826:       printf("\n");
                   4827:       fprintf(ficlog,"\n");
                   4828:     } /* end j=0 */
1.249     brouard  4829:   } /* end j */
1.252     brouard  4830: 
1.253     brouard  4831:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4832:     for(i=1, jk=1; i <=nlstate; i++){
                   4833:       for(j=1; j <=nlstate+ndeath; j++){
                   4834:        if(j!=i){
                   4835:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4836:          printf("%1d%1d",i,j);
                   4837:          fprintf(ficparo,"%1d%1d",i,j);
                   4838:          for(k=1; k<=ncovmodel;k++){
                   4839:            /*    printf(" %lf",param[i][j][k]); */
                   4840:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4841:            p[jk]=pstart[jk];
                   4842:            printf(" %f ",pstart[jk]);
                   4843:            fprintf(ficparo," %f ",pstart[jk]);
                   4844:            jk++;
                   4845:          }
                   4846:          printf("\n");
                   4847:          fprintf(ficparo,"\n");
                   4848:        }
                   4849:       }
                   4850:     }
                   4851:   } /* end mle=-2 */
1.226     brouard  4852:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4853:   
1.226     brouard  4854:   fclose(ficresp);
                   4855:   fclose(ficresphtm);
                   4856:   fclose(ficresphtmfr);
                   4857:   free_vector(meanq,1,nqfveff);
                   4858:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4859:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4860:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4861:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4862:   free_vector(pospropt,1,nlstate);
                   4863:   free_vector(posprop,1,nlstate);
1.251     brouard  4864:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4865:   free_vector(pp,1,nlstate);
                   4866:   /* End of freqsummary */
                   4867: }
1.126     brouard  4868: 
1.268     brouard  4869: /* Simple linear regression */
                   4870: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4871: 
                   4872:   /* y=a+bx regression */
                   4873:   double   sumx = 0.0;                        /* sum of x                      */
                   4874:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4875:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4876:   double   sumy = 0.0;                        /* sum of y                      */
                   4877:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4878:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4879:   double yhat;
                   4880:   
                   4881:   double denom=0;
                   4882:   int i;
                   4883:   int ne=*no;
                   4884:   
                   4885:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4886:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4887:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4888:       continue;
                   4889:     }
                   4890:     ne=ne+1;
                   4891:     sumx  += x[i];       
                   4892:     sumx2 += x[i]*x[i];  
                   4893:     sumxy += x[i] * y[i];
                   4894:     sumy  += y[i];      
                   4895:     sumy2 += y[i]*y[i]; 
                   4896:     denom = (ne * sumx2 - sumx*sumx);
                   4897:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4898:   } 
                   4899:   
                   4900:   denom = (ne * sumx2 - sumx*sumx);
                   4901:   if (denom == 0) {
                   4902:     // vertical, slope m is infinity
                   4903:     *b = INFINITY;
                   4904:     *a = 0;
                   4905:     if (r) *r = 0;
                   4906:     return 1;
                   4907:   }
                   4908:   
                   4909:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4910:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4911:   if (r!=NULL) {
                   4912:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4913:       sqrt((sumx2 - sumx*sumx/ne) *
                   4914:           (sumy2 - sumy*sumy/ne));
                   4915:   }
                   4916:   *no=ne;
                   4917:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4918:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4919:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4920:       continue;
                   4921:     }
                   4922:     ne=ne+1;
                   4923:     yhat = y[i] - *a -*b* x[i];
                   4924:     sume2  += yhat * yhat ;       
                   4925:     
                   4926:     denom = (ne * sumx2 - sumx*sumx);
                   4927:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4928:   } 
                   4929:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4930:   *sa= *sb * sqrt(sumx2/ne);
                   4931:   
                   4932:   return 0; 
                   4933: }
                   4934: 
1.126     brouard  4935: /************ Prevalence ********************/
1.227     brouard  4936: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4937: {  
                   4938:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4939:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4940:      We still use firstpass and lastpass as another selection.
                   4941:   */
1.126     brouard  4942:  
1.227     brouard  4943:   int i, m, jk, j1, bool, z1,j, iv;
                   4944:   int mi; /* Effective wave */
                   4945:   int iage;
                   4946:   double agebegin, ageend;
                   4947: 
                   4948:   double **prop;
                   4949:   double posprop; 
                   4950:   double  y2; /* in fractional years */
                   4951:   int iagemin, iagemax;
                   4952:   int first; /** to stop verbosity which is redirected to log file */
                   4953: 
                   4954:   iagemin= (int) agemin;
                   4955:   iagemax= (int) agemax;
                   4956:   /*pp=vector(1,nlstate);*/
1.251     brouard  4957:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4958:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4959:   j1=0;
1.222     brouard  4960:   
1.227     brouard  4961:   /*j=cptcoveff;*/
                   4962:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4963:   
1.227     brouard  4964:   first=1;
                   4965:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4966:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4967:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4968:        prop[i][iage]=0.0;
                   4969:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4970:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4971:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4972:     
                   4973:     for (i=1; i<=imx; i++) { /* Each individual */
                   4974:       bool=1;
                   4975:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4976:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4977:        m=mw[mi][i];
                   4978:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4979:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4980:        for (z1=1; z1<=cptcoveff; z1++){
                   4981:          if( Fixed[Tmodelind[z1]]==1){
                   4982:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4983:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4984:              bool=0;
                   4985:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4986:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4987:              bool=0;
                   4988:            }
                   4989:        }
                   4990:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4991:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4992:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4993:          if(m >=firstpass && m <=lastpass){
                   4994:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4995:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4996:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4997:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4998:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4999:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5000:                exit(1);
                   5001:              }
                   5002:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5003:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5004:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5005:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5006:              } /* end valid statuses */ 
                   5007:            } /* end selection of dates */
                   5008:          } /* end selection of waves */
                   5009:        } /* end bool */
                   5010:       } /* end wave */
                   5011:     } /* end individual */
                   5012:     for(i=iagemin; i <= iagemax+3; i++){  
                   5013:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5014:        posprop += prop[jk][i]; 
                   5015:       } 
                   5016:       
                   5017:       for(jk=1; jk <=nlstate ; jk++){      
                   5018:        if( i <=  iagemax){ 
                   5019:          if(posprop>=1.e-5){ 
                   5020:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5021:          } else{
                   5022:            if(first==1){
                   5023:              first=0;
1.266     brouard  5024:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5025:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5026:            }else{
                   5027:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5028:            }
                   5029:          }
                   5030:        } 
                   5031:       }/* end jk */ 
                   5032:     }/* end i */ 
1.222     brouard  5033:      /*} *//* end i1 */
1.227     brouard  5034:   } /* end j1 */
1.222     brouard  5035:   
1.227     brouard  5036:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5037:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5038:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5039: }  /* End of prevalence */
1.126     brouard  5040: 
                   5041: /************* Waves Concatenation ***************/
                   5042: 
                   5043: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5044: {
                   5045:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5046:      Death is a valid wave (if date is known).
                   5047:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5048:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5049:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5050:   */
1.126     brouard  5051: 
1.224     brouard  5052:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5053:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5054:      double sum=0., jmean=0.;*/
1.224     brouard  5055:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5056:   int j, k=0,jk, ju, jl;
                   5057:   double sum=0.;
                   5058:   first=0;
1.214     brouard  5059:   firstwo=0;
1.217     brouard  5060:   firsthree=0;
1.218     brouard  5061:   firstfour=0;
1.164     brouard  5062:   jmin=100000;
1.126     brouard  5063:   jmax=-1;
                   5064:   jmean=0.;
1.224     brouard  5065: 
                   5066: /* Treating live states */
1.214     brouard  5067:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5068:     mi=0;  /* First valid wave */
1.227     brouard  5069:     mli=0; /* Last valid wave */
1.126     brouard  5070:     m=firstpass;
1.214     brouard  5071:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5072:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5073:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5074:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5075:        mw[++mi][i]=m;
                   5076:        mli=m;
1.224     brouard  5077:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5078:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5079:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5080:       }
1.227     brouard  5081:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5082: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5083:        break;
1.224     brouard  5084: #else
1.227     brouard  5085:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5086:          if(firsthree == 0){
1.262     brouard  5087:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5088:            firsthree=1;
                   5089:          }
1.262     brouard  5090:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5091:          mw[++mi][i]=m;
                   5092:          mli=m;
                   5093:        }
                   5094:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5095:          nbwarn++;
                   5096:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5097:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5098:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5099:          }
                   5100:          break;
                   5101:        }
                   5102:        break;
1.224     brouard  5103: #endif
1.227     brouard  5104:       }/* End m >= lastpass */
1.126     brouard  5105:     }/* end while */
1.224     brouard  5106: 
1.227     brouard  5107:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5108:     /* After last pass */
1.224     brouard  5109: /* Treating death states */
1.214     brouard  5110:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5111:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5112:       /* } */
1.126     brouard  5113:       mi++;    /* Death is another wave */
                   5114:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5115:       /* Only death is a correct wave */
1.126     brouard  5116:       mw[mi][i]=m;
1.257     brouard  5117:     } /* else not in a death state */
1.224     brouard  5118: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5119:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5120:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5121:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5122:          nbwarn++;
                   5123:          if(firstfiv==0){
                   5124:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5125:            firstfiv=1;
                   5126:          }else{
                   5127:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5128:          }
                   5129:        }else{ /* Death occured afer last wave potential bias */
                   5130:          nberr++;
                   5131:          if(firstwo==0){
1.257     brouard  5132:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5133:            firstwo=1;
                   5134:          }
1.257     brouard  5135:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5136:        }
1.257     brouard  5137:       }else{ /* if date of interview is unknown */
1.227     brouard  5138:        /* death is known but not confirmed by death status at any wave */
                   5139:        if(firstfour==0){
                   5140:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5141:          firstfour=1;
                   5142:        }
                   5143:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5144:       }
1.224     brouard  5145:     } /* end if date of death is known */
                   5146: #endif
                   5147:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5148:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5149:     if(mi==0){
                   5150:       nbwarn++;
                   5151:       if(first==0){
1.227     brouard  5152:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5153:        first=1;
1.126     brouard  5154:       }
                   5155:       if(first==1){
1.227     brouard  5156:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5157:       }
                   5158:     } /* end mi==0 */
                   5159:   } /* End individuals */
1.214     brouard  5160:   /* wav and mw are no more changed */
1.223     brouard  5161:        
1.214     brouard  5162:   
1.126     brouard  5163:   for(i=1; i<=imx; i++){
                   5164:     for(mi=1; mi<wav[i];mi++){
                   5165:       if (stepm <=0)
1.227     brouard  5166:        dh[mi][i]=1;
1.126     brouard  5167:       else{
1.260     brouard  5168:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5169:          if (agedc[i] < 2*AGESUP) {
                   5170:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5171:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5172:            else if(j<0){
                   5173:              nberr++;
                   5174:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5175:              j=1; /* Temporary Dangerous patch */
                   5176:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5177:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5178:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5179:            }
                   5180:            k=k+1;
                   5181:            if (j >= jmax){
                   5182:              jmax=j;
                   5183:              ijmax=i;
                   5184:            }
                   5185:            if (j <= jmin){
                   5186:              jmin=j;
                   5187:              ijmin=i;
                   5188:            }
                   5189:            sum=sum+j;
                   5190:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5191:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5192:          }
                   5193:        }
                   5194:        else{
                   5195:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5196: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5197:                                        
1.227     brouard  5198:          k=k+1;
                   5199:          if (j >= jmax) {
                   5200:            jmax=j;
                   5201:            ijmax=i;
                   5202:          }
                   5203:          else if (j <= jmin){
                   5204:            jmin=j;
                   5205:            ijmin=i;
                   5206:          }
                   5207:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5208:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5209:          if(j<0){
                   5210:            nberr++;
                   5211:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5212:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5213:          }
                   5214:          sum=sum+j;
                   5215:        }
                   5216:        jk= j/stepm;
                   5217:        jl= j -jk*stepm;
                   5218:        ju= j -(jk+1)*stepm;
                   5219:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5220:          if(jl==0){
                   5221:            dh[mi][i]=jk;
                   5222:            bh[mi][i]=0;
                   5223:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5224:                  * to avoid the price of an extra matrix product in likelihood */
                   5225:            dh[mi][i]=jk+1;
                   5226:            bh[mi][i]=ju;
                   5227:          }
                   5228:        }else{
                   5229:          if(jl <= -ju){
                   5230:            dh[mi][i]=jk;
                   5231:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5232:                                 * is higher than the multiple of stepm and negative otherwise.
                   5233:                                 */
                   5234:          }
                   5235:          else{
                   5236:            dh[mi][i]=jk+1;
                   5237:            bh[mi][i]=ju;
                   5238:          }
                   5239:          if(dh[mi][i]==0){
                   5240:            dh[mi][i]=1; /* At least one step */
                   5241:            bh[mi][i]=ju; /* At least one step */
                   5242:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5243:          }
                   5244:        } /* end if mle */
1.126     brouard  5245:       }
                   5246:     } /* end wave */
                   5247:   }
                   5248:   jmean=sum/k;
                   5249:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5250:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5251: }
1.126     brouard  5252: 
                   5253: /*********** Tricode ****************************/
1.220     brouard  5254:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5255:  {
                   5256:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5257:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5258:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5259:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5260:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5261:     */
1.130     brouard  5262: 
1.242     brouard  5263:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5264:    int modmaxcovj=0; /* Modality max of covariates j */
                   5265:    int cptcode=0; /* Modality max of covariates j */
                   5266:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5267: 
                   5268: 
1.242     brouard  5269:    /* cptcoveff=0;  */
                   5270:    /* *cptcov=0; */
1.126     brouard  5271:  
1.242     brouard  5272:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5273: 
1.242     brouard  5274:    /* Loop on covariates without age and products and no quantitative variable */
                   5275:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5276:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5277:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5278:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5279:        switch(Fixed[k]) {
                   5280:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5281:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5282:           ij=(int)(covar[Tvar[k]][i]);
                   5283:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5284:            * If product of Vn*Vm, still boolean *:
                   5285:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5286:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5287:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5288:              modality of the nth covariate of individual i. */
                   5289:           if (ij > modmaxcovj)
                   5290:             modmaxcovj=ij; 
                   5291:           else if (ij < modmincovj) 
                   5292:             modmincovj=ij; 
                   5293:           if ((ij < -1) && (ij > NCOVMAX)){
                   5294:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5295:             exit(1);
                   5296:           }else
                   5297:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5298:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5299:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5300:           /* getting the maximum value of the modality of the covariate
                   5301:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5302:              female ies 1, then modmaxcovj=1.
                   5303:           */
                   5304:         } /* end for loop on individuals i */
                   5305:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5306:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5307:         cptcode=modmaxcovj;
                   5308:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5309:         /*for (i=0; i<=cptcode; i++) {*/
                   5310:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5311:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5312:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5313:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5314:             if( j != -1){
                   5315:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5316:                                  covariate for which somebody answered excluding 
                   5317:                                  undefined. Usually 2: 0 and 1. */
                   5318:             }
                   5319:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5320:                                     covariate for which somebody answered including 
                   5321:                                     undefined. Usually 3: -1, 0 and 1. */
                   5322:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5323:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5324:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5325:                        
1.242     brouard  5326:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5327:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5328:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5329:         /* modmincovj=3; modmaxcovj = 7; */
                   5330:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5331:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5332:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5333:         /* nbcode[Tvar[j]][ij]=k; */
                   5334:         /* nbcode[Tvar[j]][1]=0; */
                   5335:         /* nbcode[Tvar[j]][2]=1; */
                   5336:         /* nbcode[Tvar[j]][3]=2; */
                   5337:         /* To be continued (not working yet). */
                   5338:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5339:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5340:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5341:             break;
                   5342:           }
                   5343:           ij++;
                   5344:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5345:           cptcode = ij; /* New max modality for covar j */
                   5346:         } /* end of loop on modality i=-1 to 1 or more */
                   5347:         break;
                   5348:        case 1: /* Testing on varying covariate, could be simple and
                   5349:                * should look at waves or product of fixed *
                   5350:                * varying. No time to test -1, assuming 0 and 1 only */
                   5351:         ij=0;
                   5352:         for(i=0; i<=1;i++){
                   5353:           nbcode[Tvar[k]][++ij]=i;
                   5354:         }
                   5355:         break;
                   5356:        default:
                   5357:         break;
                   5358:        } /* end switch */
                   5359:      } /* end dummy test */
                   5360:     
                   5361:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5362:      /*        /\*recode from 0 *\/ */
                   5363:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5364:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5365:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5366:      /*        } */
                   5367:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5368:      /*        if (ij > ncodemax[j]) { */
                   5369:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5370:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5371:      /*          break; */
                   5372:      /*        } */
                   5373:      /*   }  /\* end of loop on modality k *\/ */
                   5374:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5375:   
                   5376:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5377:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5378:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5379:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5380:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5381:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5382:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5383:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5384:   
                   5385:    ij=0;
                   5386:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5387:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5388:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5389:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5390:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5391:        /* If product not in single variable we don't print results */
                   5392:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5393:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5394:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5395:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5396:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5397:        if(Fixed[k]!=0)
                   5398:         anyvaryingduminmodel=1;
                   5399:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5400:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5401:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5402:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5403:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5404:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5405:      } 
                   5406:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5407:    /* ij--; */
                   5408:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5409:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5410:                * because they can be excluded from the model and real
                   5411:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5412:    for(j=ij+1; j<= cptcovt; j++){
                   5413:      Tvaraff[j]=0;
                   5414:      Tmodelind[j]=0;
                   5415:    }
                   5416:    for(j=ntveff+1; j<= cptcovt; j++){
                   5417:      TmodelInvind[j]=0;
                   5418:    }
                   5419:    /* To be sorted */
                   5420:    ;
                   5421:  }
1.126     brouard  5422: 
1.145     brouard  5423: 
1.126     brouard  5424: /*********** Health Expectancies ****************/
                   5425: 
1.235     brouard  5426:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5427: 
                   5428: {
                   5429:   /* Health expectancies, no variances */
1.164     brouard  5430:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5431:   int nhstepma, nstepma; /* Decreasing with age */
                   5432:   double age, agelim, hf;
                   5433:   double ***p3mat;
                   5434:   double eip;
                   5435: 
1.238     brouard  5436:   /* pstamp(ficreseij); */
1.126     brouard  5437:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5438:   fprintf(ficreseij,"# Age");
                   5439:   for(i=1; i<=nlstate;i++){
                   5440:     for(j=1; j<=nlstate;j++){
                   5441:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5442:     }
                   5443:     fprintf(ficreseij," e%1d. ",i);
                   5444:   }
                   5445:   fprintf(ficreseij,"\n");
                   5446: 
                   5447:   
                   5448:   if(estepm < stepm){
                   5449:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5450:   }
                   5451:   else  hstepm=estepm;   
                   5452:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5453:    * This is mainly to measure the difference between two models: for example
                   5454:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5455:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5456:    * progression in between and thus overestimating or underestimating according
                   5457:    * to the curvature of the survival function. If, for the same date, we 
                   5458:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5459:    * to compare the new estimate of Life expectancy with the same linear 
                   5460:    * hypothesis. A more precise result, taking into account a more precise
                   5461:    * curvature will be obtained if estepm is as small as stepm. */
                   5462: 
                   5463:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5464:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5465:      nhstepm is the number of hstepm from age to agelim 
                   5466:      nstepm is the number of stepm from age to agelin. 
1.270   ! brouard  5467:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5468:      and note for a fixed period like estepm months */
                   5469:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5470:      survival function given by stepm (the optimization length). Unfortunately it
                   5471:      means that if the survival funtion is printed only each two years of age and if
                   5472:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5473:      results. So we changed our mind and took the option of the best precision.
                   5474:   */
                   5475:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5476: 
                   5477:   agelim=AGESUP;
                   5478:   /* If stepm=6 months */
                   5479:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5480:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5481:     
                   5482: /* nhstepm age range expressed in number of stepm */
                   5483:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5484:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5485:   /* if (stepm >= YEARM) hstepm=1;*/
                   5486:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5487:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5488: 
                   5489:   for (age=bage; age<=fage; age ++){ 
                   5490:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5491:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5492:     /* if (stepm >= YEARM) hstepm=1;*/
                   5493:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5494: 
                   5495:     /* If stepm=6 months */
                   5496:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5497:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5498:     
1.235     brouard  5499:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5500:     
                   5501:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5502:     
                   5503:     printf("%d|",(int)age);fflush(stdout);
                   5504:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5505:     
                   5506:     /* Computing expectancies */
                   5507:     for(i=1; i<=nlstate;i++)
                   5508:       for(j=1; j<=nlstate;j++)
                   5509:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5510:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5511:          
                   5512:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5513: 
                   5514:        }
                   5515: 
                   5516:     fprintf(ficreseij,"%3.0f",age );
                   5517:     for(i=1; i<=nlstate;i++){
                   5518:       eip=0;
                   5519:       for(j=1; j<=nlstate;j++){
                   5520:        eip +=eij[i][j][(int)age];
                   5521:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5522:       }
                   5523:       fprintf(ficreseij,"%9.4f", eip );
                   5524:     }
                   5525:     fprintf(ficreseij,"\n");
                   5526:     
                   5527:   }
                   5528:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5529:   printf("\n");
                   5530:   fprintf(ficlog,"\n");
                   5531:   
                   5532: }
                   5533: 
1.235     brouard  5534:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5535: 
                   5536: {
                   5537:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5538:      to initial status i, ei. .
1.126     brouard  5539:   */
                   5540:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5541:   int nhstepma, nstepma; /* Decreasing with age */
                   5542:   double age, agelim, hf;
                   5543:   double ***p3matp, ***p3matm, ***varhe;
                   5544:   double **dnewm,**doldm;
                   5545:   double *xp, *xm;
                   5546:   double **gp, **gm;
                   5547:   double ***gradg, ***trgradg;
                   5548:   int theta;
                   5549: 
                   5550:   double eip, vip;
                   5551: 
                   5552:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5553:   xp=vector(1,npar);
                   5554:   xm=vector(1,npar);
                   5555:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5556:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5557:   
                   5558:   pstamp(ficresstdeij);
                   5559:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5560:   fprintf(ficresstdeij,"# Age");
                   5561:   for(i=1; i<=nlstate;i++){
                   5562:     for(j=1; j<=nlstate;j++)
                   5563:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5564:     fprintf(ficresstdeij," e%1d. ",i);
                   5565:   }
                   5566:   fprintf(ficresstdeij,"\n");
                   5567: 
                   5568:   pstamp(ficrescveij);
                   5569:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5570:   fprintf(ficrescveij,"# Age");
                   5571:   for(i=1; i<=nlstate;i++)
                   5572:     for(j=1; j<=nlstate;j++){
                   5573:       cptj= (j-1)*nlstate+i;
                   5574:       for(i2=1; i2<=nlstate;i2++)
                   5575:        for(j2=1; j2<=nlstate;j2++){
                   5576:          cptj2= (j2-1)*nlstate+i2;
                   5577:          if(cptj2 <= cptj)
                   5578:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5579:        }
                   5580:     }
                   5581:   fprintf(ficrescveij,"\n");
                   5582:   
                   5583:   if(estepm < stepm){
                   5584:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5585:   }
                   5586:   else  hstepm=estepm;   
                   5587:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5588:    * This is mainly to measure the difference between two models: for example
                   5589:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5590:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5591:    * progression in between and thus overestimating or underestimating according
                   5592:    * to the curvature of the survival function. If, for the same date, we 
                   5593:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5594:    * to compare the new estimate of Life expectancy with the same linear 
                   5595:    * hypothesis. A more precise result, taking into account a more precise
                   5596:    * curvature will be obtained if estepm is as small as stepm. */
                   5597: 
                   5598:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5599:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5600:      nhstepm is the number of hstepm from age to agelim 
                   5601:      nstepm is the number of stepm from age to agelin. 
                   5602:      Look at hpijx to understand the reason of that which relies in memory size
                   5603:      and note for a fixed period like estepm months */
                   5604:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5605:      survival function given by stepm (the optimization length). Unfortunately it
                   5606:      means that if the survival funtion is printed only each two years of age and if
                   5607:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5608:      results. So we changed our mind and took the option of the best precision.
                   5609:   */
                   5610:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5611: 
                   5612:   /* If stepm=6 months */
                   5613:   /* nhstepm age range expressed in number of stepm */
                   5614:   agelim=AGESUP;
                   5615:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5616:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5617:   /* if (stepm >= YEARM) hstepm=1;*/
                   5618:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5619:   
                   5620:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5621:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5622:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5623:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5624:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5625:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5626: 
                   5627:   for (age=bage; age<=fage; age ++){ 
                   5628:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5629:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5630:     /* if (stepm >= YEARM) hstepm=1;*/
                   5631:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5632:                
1.126     brouard  5633:     /* If stepm=6 months */
                   5634:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5635:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5636:     
                   5637:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5638:                
1.126     brouard  5639:     /* Computing  Variances of health expectancies */
                   5640:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5641:        decrease memory allocation */
                   5642:     for(theta=1; theta <=npar; theta++){
                   5643:       for(i=1; i<=npar; i++){ 
1.222     brouard  5644:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5645:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5646:       }
1.235     brouard  5647:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5648:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5649:                        
1.126     brouard  5650:       for(j=1; j<= nlstate; j++){
1.222     brouard  5651:        for(i=1; i<=nlstate; i++){
                   5652:          for(h=0; h<=nhstepm-1; h++){
                   5653:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5654:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5655:          }
                   5656:        }
1.126     brouard  5657:       }
1.218     brouard  5658:                        
1.126     brouard  5659:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5660:        for(h=0; h<=nhstepm-1; h++){
                   5661:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5662:        }
1.126     brouard  5663:     }/* End theta */
                   5664:     
                   5665:     
                   5666:     for(h=0; h<=nhstepm-1; h++)
                   5667:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5668:        for(theta=1; theta <=npar; theta++)
                   5669:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5670:     
1.218     brouard  5671:                
1.222     brouard  5672:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5673:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5674:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5675:                
1.222     brouard  5676:     printf("%d|",(int)age);fflush(stdout);
                   5677:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5678:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5679:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5680:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5681:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5682:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5683:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5684:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5685:       }
                   5686:     }
1.218     brouard  5687:                
1.126     brouard  5688:     /* Computing expectancies */
1.235     brouard  5689:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5690:     for(i=1; i<=nlstate;i++)
                   5691:       for(j=1; j<=nlstate;j++)
1.222     brouard  5692:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5693:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5694:                                        
1.222     brouard  5695:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5696:                                        
1.222     brouard  5697:        }
1.269     brouard  5698: 
                   5699:     /* Standard deviation of expectancies ij */                
1.126     brouard  5700:     fprintf(ficresstdeij,"%3.0f",age );
                   5701:     for(i=1; i<=nlstate;i++){
                   5702:       eip=0.;
                   5703:       vip=0.;
                   5704:       for(j=1; j<=nlstate;j++){
1.222     brouard  5705:        eip += eij[i][j][(int)age];
                   5706:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5707:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5708:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5709:       }
                   5710:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5711:     }
                   5712:     fprintf(ficresstdeij,"\n");
1.218     brouard  5713:                
1.269     brouard  5714:     /* Variance of expectancies ij */          
1.126     brouard  5715:     fprintf(ficrescveij,"%3.0f",age );
                   5716:     for(i=1; i<=nlstate;i++)
                   5717:       for(j=1; j<=nlstate;j++){
1.222     brouard  5718:        cptj= (j-1)*nlstate+i;
                   5719:        for(i2=1; i2<=nlstate;i2++)
                   5720:          for(j2=1; j2<=nlstate;j2++){
                   5721:            cptj2= (j2-1)*nlstate+i2;
                   5722:            if(cptj2 <= cptj)
                   5723:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5724:          }
1.126     brouard  5725:       }
                   5726:     fprintf(ficrescveij,"\n");
1.218     brouard  5727:                
1.126     brouard  5728:   }
                   5729:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5730:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5731:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5732:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5733:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5734:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5735:   printf("\n");
                   5736:   fprintf(ficlog,"\n");
1.218     brouard  5737:        
1.126     brouard  5738:   free_vector(xm,1,npar);
                   5739:   free_vector(xp,1,npar);
                   5740:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5741:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5742:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5743: }
1.218     brouard  5744:  
1.126     brouard  5745: /************ Variance ******************/
1.235     brouard  5746:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5747:  {
                   5748:    /* Variance of health expectancies */
                   5749:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5750:    /* double **newm;*/
                   5751:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5752:   
                   5753:    /* int movingaverage(); */
                   5754:    double **dnewm,**doldm;
                   5755:    double **dnewmp,**doldmp;
                   5756:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5757:    int k;
                   5758:    double *xp;
                   5759:    double **gp, **gm;  /* for var eij */
                   5760:    double ***gradg, ***trgradg; /*for var eij */
                   5761:    double **gradgp, **trgradgp; /* for var p point j */
                   5762:    double *gpp, *gmp; /* for var p point j */
                   5763:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5764:    double ***p3mat;
                   5765:    double age,agelim, hf;
                   5766:    /* double ***mobaverage; */
                   5767:    int theta;
                   5768:    char digit[4];
                   5769:    char digitp[25];
                   5770: 
                   5771:    char fileresprobmorprev[FILENAMELENGTH];
                   5772: 
                   5773:    if(popbased==1){
                   5774:      if(mobilav!=0)
                   5775:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5776:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5777:    }
                   5778:    else 
                   5779:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5780: 
1.218     brouard  5781:    /* if (mobilav!=0) { */
                   5782:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5783:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5784:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5785:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5786:    /*   } */
                   5787:    /* } */
                   5788: 
                   5789:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5790:    sprintf(digit,"%-d",ij);
                   5791:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5792:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5793:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5794:    strcat(fileresprobmorprev,fileresu);
                   5795:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5796:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5797:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5798:    }
                   5799:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5800:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5801:    pstamp(ficresprobmorprev);
                   5802:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5803:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5804:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5805:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5806:    }
                   5807:    for(j=1;j<=cptcoveff;j++) 
                   5808:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5809:    fprintf(ficresprobmorprev,"\n");
                   5810: 
1.218     brouard  5811:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5812:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5813:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5814:      for(i=1; i<=nlstate;i++)
                   5815:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5816:    }  
                   5817:    fprintf(ficresprobmorprev,"\n");
                   5818:   
                   5819:    fprintf(ficgp,"\n# Routine varevsij");
                   5820:    fprintf(ficgp,"\nunset title \n");
                   5821:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5822:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5823:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5824:    /*   } */
                   5825:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5826:    pstamp(ficresvij);
                   5827:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5828:    if(popbased==1)
                   5829:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5830:    else
                   5831:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5832:    fprintf(ficresvij,"# Age");
                   5833:    for(i=1; i<=nlstate;i++)
                   5834:      for(j=1; j<=nlstate;j++)
                   5835:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5836:    fprintf(ficresvij,"\n");
                   5837: 
                   5838:    xp=vector(1,npar);
                   5839:    dnewm=matrix(1,nlstate,1,npar);
                   5840:    doldm=matrix(1,nlstate,1,nlstate);
                   5841:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5842:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5843: 
                   5844:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5845:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5846:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5847:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5848:   
1.218     brouard  5849:    if(estepm < stepm){
                   5850:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5851:    }
                   5852:    else  hstepm=estepm;   
                   5853:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5854:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5855:       nhstepm is the number of hstepm from age to agelim 
                   5856:       nstepm is the number of stepm from age to agelim. 
                   5857:       Look at function hpijx to understand why because of memory size limitations, 
                   5858:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5859:       survival function given by stepm (the optimization length). Unfortunately it
                   5860:       means that if the survival funtion is printed every two years of age and if
                   5861:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5862:       results. So we changed our mind and took the option of the best precision.
                   5863:    */
                   5864:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5865:    agelim = AGESUP;
                   5866:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5867:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5868:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5869:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5870:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5871:      gp=matrix(0,nhstepm,1,nlstate);
                   5872:      gm=matrix(0,nhstepm,1,nlstate);
                   5873:                
                   5874:                
                   5875:      for(theta=1; theta <=npar; theta++){
                   5876:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5877:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5878:        }
                   5879:                        
1.242     brouard  5880:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5881:                        
                   5882:        if (popbased==1) {
                   5883:         if(mobilav ==0){
                   5884:           for(i=1; i<=nlstate;i++)
                   5885:             prlim[i][i]=probs[(int)age][i][ij];
                   5886:         }else{ /* mobilav */ 
                   5887:           for(i=1; i<=nlstate;i++)
                   5888:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5889:         }
                   5890:        }
                   5891:                        
1.235     brouard  5892:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5893:        for(j=1; j<= nlstate; j++){
                   5894:         for(h=0; h<=nhstepm; h++){
                   5895:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5896:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5897:         }
                   5898:        }
                   5899:        /* Next for computing probability of death (h=1 means
                   5900:          computed over hstepm matrices product = hstepm*stepm months) 
                   5901:          as a weighted average of prlim.
                   5902:        */
                   5903:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5904:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5905:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5906:        }    
                   5907:        /* end probability of death */
                   5908:                        
                   5909:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5910:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5911:                        
1.242     brouard  5912:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5913:                        
                   5914:        if (popbased==1) {
                   5915:         if(mobilav ==0){
                   5916:           for(i=1; i<=nlstate;i++)
                   5917:             prlim[i][i]=probs[(int)age][i][ij];
                   5918:         }else{ /* mobilav */ 
                   5919:           for(i=1; i<=nlstate;i++)
                   5920:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5921:         }
                   5922:        }
                   5923:                        
1.235     brouard  5924:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5925:                        
                   5926:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5927:         for(h=0; h<=nhstepm; h++){
                   5928:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5929:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5930:         }
                   5931:        }
                   5932:        /* This for computing probability of death (h=1 means
                   5933:          computed over hstepm matrices product = hstepm*stepm months) 
                   5934:          as a weighted average of prlim.
                   5935:        */
                   5936:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5937:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5938:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5939:        }    
                   5940:        /* end probability of death */
                   5941:                        
                   5942:        for(j=1; j<= nlstate; j++) /* vareij */
                   5943:         for(h=0; h<=nhstepm; h++){
                   5944:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5945:         }
                   5946:                        
                   5947:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5948:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5949:        }
                   5950:                        
                   5951:      } /* End theta */
                   5952:                
                   5953:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5954:                
                   5955:      for(h=0; h<=nhstepm; h++) /* veij */
                   5956:        for(j=1; j<=nlstate;j++)
                   5957:         for(theta=1; theta <=npar; theta++)
                   5958:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5959:                
                   5960:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5961:        for(theta=1; theta <=npar; theta++)
                   5962:         trgradgp[j][theta]=gradgp[theta][j];
                   5963:                
                   5964:                
                   5965:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5966:      for(i=1;i<=nlstate;i++)
                   5967:        for(j=1;j<=nlstate;j++)
                   5968:         vareij[i][j][(int)age] =0.;
                   5969:                
                   5970:      for(h=0;h<=nhstepm;h++){
                   5971:        for(k=0;k<=nhstepm;k++){
                   5972:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5973:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5974:         for(i=1;i<=nlstate;i++)
                   5975:           for(j=1;j<=nlstate;j++)
                   5976:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5977:        }
                   5978:      }
                   5979:                
                   5980:      /* pptj */
                   5981:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5982:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5983:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5984:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5985:         varppt[j][i]=doldmp[j][i];
                   5986:      /* end ppptj */
                   5987:      /*  x centered again */
                   5988:                
1.242     brouard  5989:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5990:                
                   5991:      if (popbased==1) {
                   5992:        if(mobilav ==0){
                   5993:         for(i=1; i<=nlstate;i++)
                   5994:           prlim[i][i]=probs[(int)age][i][ij];
                   5995:        }else{ /* mobilav */ 
                   5996:         for(i=1; i<=nlstate;i++)
                   5997:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5998:        }
                   5999:      }
                   6000:                
                   6001:      /* This for computing probability of death (h=1 means
                   6002:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6003:        as a weighted average of prlim.
                   6004:      */
1.235     brouard  6005:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6006:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6007:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6008:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6009:      }    
                   6010:      /* end probability of death */
                   6011:                
                   6012:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6013:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6014:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6015:        for(i=1; i<=nlstate;i++){
                   6016:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6017:        }
                   6018:      } 
                   6019:      fprintf(ficresprobmorprev,"\n");
                   6020:                
                   6021:      fprintf(ficresvij,"%.0f ",age );
                   6022:      for(i=1; i<=nlstate;i++)
                   6023:        for(j=1; j<=nlstate;j++){
                   6024:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6025:        }
                   6026:      fprintf(ficresvij,"\n");
                   6027:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6028:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6029:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6030:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6031:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6032:    } /* End age */
                   6033:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6034:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6035:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6036:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6037:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6038:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6039:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6040:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6041:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6042:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6043:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6044:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6045:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6046:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6047:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6048:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6049:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6050:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6051:     */
1.218     brouard  6052:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6053:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6054: 
1.218     brouard  6055:    free_vector(xp,1,npar);
                   6056:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6057:    free_matrix(dnewm,1,nlstate,1,npar);
                   6058:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6059:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6060:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6061:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6062:    fclose(ficresprobmorprev);
                   6063:    fflush(ficgp);
                   6064:    fflush(fichtm); 
                   6065:  }  /* end varevsij */
1.126     brouard  6066: 
                   6067: /************ Variance of prevlim ******************/
1.269     brouard  6068:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6069: {
1.205     brouard  6070:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6071:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6072: 
1.268     brouard  6073:   double **dnewmpar,**doldm;
1.126     brouard  6074:   int i, j, nhstepm, hstepm;
                   6075:   double *xp;
                   6076:   double *gp, *gm;
                   6077:   double **gradg, **trgradg;
1.208     brouard  6078:   double **mgm, **mgp;
1.126     brouard  6079:   double age,agelim;
                   6080:   int theta;
                   6081:   
                   6082:   pstamp(ficresvpl);
                   6083:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6084:   fprintf(ficresvpl,"# Age ");
                   6085:   if(nresult >=1)
                   6086:     fprintf(ficresvpl," Result# ");
1.126     brouard  6087:   for(i=1; i<=nlstate;i++)
                   6088:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6089:   fprintf(ficresvpl,"\n");
                   6090: 
                   6091:   xp=vector(1,npar);
1.268     brouard  6092:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6093:   doldm=matrix(1,nlstate,1,nlstate);
                   6094:   
                   6095:   hstepm=1*YEARM; /* Every year of age */
                   6096:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6097:   agelim = AGESUP;
                   6098:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6099:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6100:     if (stepm >= YEARM) hstepm=1;
                   6101:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6102:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6103:     mgp=matrix(1,npar,1,nlstate);
                   6104:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6105:     gp=vector(1,nlstate);
                   6106:     gm=vector(1,nlstate);
                   6107: 
                   6108:     for(theta=1; theta <=npar; theta++){
                   6109:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6110:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6111:       }
1.209     brouard  6112:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6113:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6114:       else
1.235     brouard  6115:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6116:       for(i=1;i<=nlstate;i++){
1.126     brouard  6117:        gp[i] = prlim[i][i];
1.208     brouard  6118:        mgp[theta][i] = prlim[i][i];
                   6119:       }
1.126     brouard  6120:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6121:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6122:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6123:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6124:       else
1.235     brouard  6125:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6126:       for(i=1;i<=nlstate;i++){
1.126     brouard  6127:        gm[i] = prlim[i][i];
1.208     brouard  6128:        mgm[theta][i] = prlim[i][i];
                   6129:       }
1.126     brouard  6130:       for(i=1;i<=nlstate;i++)
                   6131:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6132:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6133:     } /* End theta */
                   6134: 
                   6135:     trgradg =matrix(1,nlstate,1,npar);
                   6136: 
                   6137:     for(j=1; j<=nlstate;j++)
                   6138:       for(theta=1; theta <=npar; theta++)
                   6139:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6140:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6141:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6142:     /*   for(j=1; j<=nlstate;j++){ */
                   6143:     /*         printf(" %d ",j); */
                   6144:     /*         for(theta=1; theta <=npar; theta++) */
                   6145:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6146:     /*         printf("\n "); */
                   6147:     /*   } */
                   6148:     /* } */
                   6149:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6150:     /*   printf("\n gradg %d ",(int)age); */
                   6151:     /*   for(j=1; j<=nlstate;j++){ */
                   6152:     /*         printf("%d ",j); */
                   6153:     /*         for(theta=1; theta <=npar; theta++) */
                   6154:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6155:     /*         printf("\n "); */
                   6156:     /*   } */
                   6157:     /* } */
1.126     brouard  6158: 
                   6159:     for(i=1;i<=nlstate;i++)
                   6160:       varpl[i][(int)age] =0.;
1.209     brouard  6161:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6162:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6163:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6164:     }else{
1.268     brouard  6165:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6166:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6167:     }
1.126     brouard  6168:     for(i=1;i<=nlstate;i++)
                   6169:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6170: 
                   6171:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6172:     if(nresult >=1)
                   6173:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6174:     for(i=1; i<=nlstate;i++)
                   6175:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6176:     fprintf(ficresvpl,"\n");
                   6177:     free_vector(gp,1,nlstate);
                   6178:     free_vector(gm,1,nlstate);
1.208     brouard  6179:     free_matrix(mgm,1,npar,1,nlstate);
                   6180:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6181:     free_matrix(gradg,1,npar,1,nlstate);
                   6182:     free_matrix(trgradg,1,nlstate,1,npar);
                   6183:   } /* End age */
                   6184: 
                   6185:   free_vector(xp,1,npar);
                   6186:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6187:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6188: 
                   6189: }
                   6190: 
                   6191: 
                   6192: /************ Variance of backprevalence limit ******************/
1.269     brouard  6193:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6194: {
                   6195:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6196:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6197: 
                   6198:   double **dnewmpar,**doldm;
                   6199:   int i, j, nhstepm, hstepm;
                   6200:   double *xp;
                   6201:   double *gp, *gm;
                   6202:   double **gradg, **trgradg;
                   6203:   double **mgm, **mgp;
                   6204:   double age,agelim;
                   6205:   int theta;
                   6206:   
                   6207:   pstamp(ficresvbl);
                   6208:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6209:   fprintf(ficresvbl,"# Age ");
                   6210:   if(nresult >=1)
                   6211:     fprintf(ficresvbl," Result# ");
                   6212:   for(i=1; i<=nlstate;i++)
                   6213:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6214:   fprintf(ficresvbl,"\n");
                   6215: 
                   6216:   xp=vector(1,npar);
                   6217:   dnewmpar=matrix(1,nlstate,1,npar);
                   6218:   doldm=matrix(1,nlstate,1,nlstate);
                   6219:   
                   6220:   hstepm=1*YEARM; /* Every year of age */
                   6221:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6222:   agelim = AGEINF;
                   6223:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6224:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6225:     if (stepm >= YEARM) hstepm=1;
                   6226:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6227:     gradg=matrix(1,npar,1,nlstate);
                   6228:     mgp=matrix(1,npar,1,nlstate);
                   6229:     mgm=matrix(1,npar,1,nlstate);
                   6230:     gp=vector(1,nlstate);
                   6231:     gm=vector(1,nlstate);
                   6232: 
                   6233:     for(theta=1; theta <=npar; theta++){
                   6234:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6235:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6236:       }
                   6237:       if(mobilavproj > 0 )
                   6238:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6239:       else
                   6240:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6241:       for(i=1;i<=nlstate;i++){
                   6242:        gp[i] = bprlim[i][i];
                   6243:        mgp[theta][i] = bprlim[i][i];
                   6244:       }
                   6245:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6246:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6247:        if(mobilavproj > 0 )
                   6248:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6249:        else
                   6250:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6251:       for(i=1;i<=nlstate;i++){
                   6252:        gm[i] = bprlim[i][i];
                   6253:        mgm[theta][i] = bprlim[i][i];
                   6254:       }
                   6255:       for(i=1;i<=nlstate;i++)
                   6256:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6257:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6258:     } /* End theta */
                   6259: 
                   6260:     trgradg =matrix(1,nlstate,1,npar);
                   6261: 
                   6262:     for(j=1; j<=nlstate;j++)
                   6263:       for(theta=1; theta <=npar; theta++)
                   6264:        trgradg[j][theta]=gradg[theta][j];
                   6265:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6266:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6267:     /*   for(j=1; j<=nlstate;j++){ */
                   6268:     /*         printf(" %d ",j); */
                   6269:     /*         for(theta=1; theta <=npar; theta++) */
                   6270:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6271:     /*         printf("\n "); */
                   6272:     /*   } */
                   6273:     /* } */
                   6274:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6275:     /*   printf("\n gradg %d ",(int)age); */
                   6276:     /*   for(j=1; j<=nlstate;j++){ */
                   6277:     /*         printf("%d ",j); */
                   6278:     /*         for(theta=1; theta <=npar; theta++) */
                   6279:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6280:     /*         printf("\n "); */
                   6281:     /*   } */
                   6282:     /* } */
                   6283: 
                   6284:     for(i=1;i<=nlstate;i++)
                   6285:       varbpl[i][(int)age] =0.;
                   6286:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6287:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6288:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6289:     }else{
                   6290:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6291:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6292:     }
                   6293:     for(i=1;i<=nlstate;i++)
                   6294:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6295: 
                   6296:     fprintf(ficresvbl,"%.0f ",age );
                   6297:     if(nresult >=1)
                   6298:       fprintf(ficresvbl,"%d ",nres );
                   6299:     for(i=1; i<=nlstate;i++)
                   6300:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6301:     fprintf(ficresvbl,"\n");
                   6302:     free_vector(gp,1,nlstate);
                   6303:     free_vector(gm,1,nlstate);
                   6304:     free_matrix(mgm,1,npar,1,nlstate);
                   6305:     free_matrix(mgp,1,npar,1,nlstate);
                   6306:     free_matrix(gradg,1,npar,1,nlstate);
                   6307:     free_matrix(trgradg,1,nlstate,1,npar);
                   6308:   } /* End age */
                   6309: 
                   6310:   free_vector(xp,1,npar);
                   6311:   free_matrix(doldm,1,nlstate,1,npar);
                   6312:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6313: 
                   6314: }
                   6315: 
                   6316: /************ Variance of one-step probabilities  ******************/
                   6317: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6318:  {
                   6319:    int i, j=0,  k1, l1, tj;
                   6320:    int k2, l2, j1,  z1;
                   6321:    int k=0, l;
                   6322:    int first=1, first1, first2;
                   6323:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6324:    double **dnewm,**doldm;
                   6325:    double *xp;
                   6326:    double *gp, *gm;
                   6327:    double **gradg, **trgradg;
                   6328:    double **mu;
                   6329:    double age, cov[NCOVMAX+1];
                   6330:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6331:    int theta;
                   6332:    char fileresprob[FILENAMELENGTH];
                   6333:    char fileresprobcov[FILENAMELENGTH];
                   6334:    char fileresprobcor[FILENAMELENGTH];
                   6335:    double ***varpij;
                   6336: 
                   6337:    strcpy(fileresprob,"PROB_"); 
                   6338:    strcat(fileresprob,fileres);
                   6339:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6340:      printf("Problem with resultfile: %s\n", fileresprob);
                   6341:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6342:    }
                   6343:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6344:    strcat(fileresprobcov,fileresu);
                   6345:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6346:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6347:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6348:    }
                   6349:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6350:    strcat(fileresprobcor,fileresu);
                   6351:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6352:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6353:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6354:    }
                   6355:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6356:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6357:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6358:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6359:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6360:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6361:    pstamp(ficresprob);
                   6362:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6363:    fprintf(ficresprob,"# Age");
                   6364:    pstamp(ficresprobcov);
                   6365:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6366:    fprintf(ficresprobcov,"# Age");
                   6367:    pstamp(ficresprobcor);
                   6368:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6369:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6370: 
                   6371: 
1.222     brouard  6372:    for(i=1; i<=nlstate;i++)
                   6373:      for(j=1; j<=(nlstate+ndeath);j++){
                   6374:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6375:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6376:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6377:      }  
                   6378:    /* fprintf(ficresprob,"\n");
                   6379:       fprintf(ficresprobcov,"\n");
                   6380:       fprintf(ficresprobcor,"\n");
                   6381:    */
                   6382:    xp=vector(1,npar);
                   6383:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6384:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6385:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6386:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6387:    first=1;
                   6388:    fprintf(ficgp,"\n# Routine varprob");
                   6389:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6390:    fprintf(fichtm,"\n");
                   6391: 
1.266     brouard  6392:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6393:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6394:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6395: and drawn. It helps understanding how is the covariance between two incidences.\
                   6396:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6397:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6398: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6399: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6400: standard deviations wide on each axis. <br>\
                   6401:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6402:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6403: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6404: 
1.222     brouard  6405:    cov[1]=1;
                   6406:    /* tj=cptcoveff; */
1.225     brouard  6407:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6408:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6409:    j1=0;
1.224     brouard  6410:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6411:      if  (cptcovn>0) {
                   6412:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6413:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6414:        fprintf(ficresprob, "**********\n#\n");
                   6415:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6416:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6417:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6418:                        
1.222     brouard  6419:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6420:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6421:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6422:                        
                   6423:                        
1.222     brouard  6424:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6425:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6426:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6427:                        
1.222     brouard  6428:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6429:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6430:        fprintf(ficresprobcor, "**********\n#");    
                   6431:        if(invalidvarcomb[j1]){
                   6432:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6433:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6434:         continue;
                   6435:        }
                   6436:      }
                   6437:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6438:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6439:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6440:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6441:      for (age=bage; age<=fage; age ++){ 
                   6442:        cov[2]=age;
                   6443:        if(nagesqr==1)
                   6444:         cov[3]= age*age;
                   6445:        for (k=1; k<=cptcovn;k++) {
                   6446:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6447:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6448:                                                                    * 1  1 1 1 1
                   6449:                                                                    * 2  2 1 1 1
                   6450:                                                                    * 3  1 2 1 1
                   6451:                                                                    */
                   6452:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6453:        }
                   6454:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6455:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6456:        for (k=1; k<=cptcovprod;k++)
                   6457:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6458:                        
                   6459:                        
1.222     brouard  6460:        for(theta=1; theta <=npar; theta++){
                   6461:         for(i=1; i<=npar; i++)
                   6462:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6463:                                
1.222     brouard  6464:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6465:                                
1.222     brouard  6466:         k=0;
                   6467:         for(i=1; i<= (nlstate); i++){
                   6468:           for(j=1; j<=(nlstate+ndeath);j++){
                   6469:             k=k+1;
                   6470:             gp[k]=pmmij[i][j];
                   6471:           }
                   6472:         }
1.220     brouard  6473:                                
1.222     brouard  6474:         for(i=1; i<=npar; i++)
                   6475:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6476:                                
1.222     brouard  6477:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6478:         k=0;
                   6479:         for(i=1; i<=(nlstate); i++){
                   6480:           for(j=1; j<=(nlstate+ndeath);j++){
                   6481:             k=k+1;
                   6482:             gm[k]=pmmij[i][j];
                   6483:           }
                   6484:         }
1.220     brouard  6485:                                
1.222     brouard  6486:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6487:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6488:        }
1.126     brouard  6489: 
1.222     brouard  6490:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6491:         for(theta=1; theta <=npar; theta++)
                   6492:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6493:                        
1.222     brouard  6494:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6495:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6496:                        
1.222     brouard  6497:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6498:                        
1.222     brouard  6499:        k=0;
                   6500:        for(i=1; i<=(nlstate); i++){
                   6501:         for(j=1; j<=(nlstate+ndeath);j++){
                   6502:           k=k+1;
                   6503:           mu[k][(int) age]=pmmij[i][j];
                   6504:         }
                   6505:        }
                   6506:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6507:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6508:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6509:                        
1.222     brouard  6510:        /*printf("\n%d ",(int)age);
                   6511:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6512:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6513:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6514:         }*/
1.220     brouard  6515:                        
1.222     brouard  6516:        fprintf(ficresprob,"\n%d ",(int)age);
                   6517:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6518:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6519:                        
1.222     brouard  6520:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6521:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6522:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6523:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6524:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6525:        }
                   6526:        i=0;
                   6527:        for (k=1; k<=(nlstate);k++){
                   6528:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6529:           i++;
                   6530:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6531:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6532:           for (j=1; j<=i;j++){
                   6533:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6534:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6535:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6536:           }
                   6537:         }
                   6538:        }/* end of loop for state */
                   6539:      } /* end of loop for age */
                   6540:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6541:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6542:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6543:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6544:     
                   6545:      /* Confidence intervalle of pij  */
                   6546:      /*
                   6547:        fprintf(ficgp,"\nunset parametric;unset label");
                   6548:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6549:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6550:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6551:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6552:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6553:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6554:      */
                   6555:                
                   6556:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6557:      first1=1;first2=2;
                   6558:      for (k2=1; k2<=(nlstate);k2++){
                   6559:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6560:         if(l2==k2) continue;
                   6561:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6562:         for (k1=1; k1<=(nlstate);k1++){
                   6563:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6564:             if(l1==k1) continue;
                   6565:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6566:             if(i<=j) continue;
                   6567:             for (age=bage; age<=fage; age ++){ 
                   6568:               if ((int)age %5==0){
                   6569:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6570:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6571:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6572:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6573:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6574:                 c12=cv12/sqrt(v1*v2);
                   6575:                 /* Computing eigen value of matrix of covariance */
                   6576:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6577:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6578:                 if ((lc2 <0) || (lc1 <0) ){
                   6579:                   if(first2==1){
                   6580:                     first1=0;
                   6581:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6582:                   }
                   6583:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6584:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6585:                   /* lc2=fabs(lc2); */
                   6586:                 }
1.220     brouard  6587:                                                                
1.222     brouard  6588:                 /* Eigen vectors */
                   6589:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6590:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6591:                 v21=(lc1-v1)/cv12*v11;
                   6592:                 v12=-v21;
                   6593:                 v22=v11;
                   6594:                 tnalp=v21/v11;
                   6595:                 if(first1==1){
                   6596:                   first1=0;
                   6597:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6598:                 }
                   6599:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6600:                 /*printf(fignu*/
                   6601:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6602:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6603:                 if(first==1){
                   6604:                   first=0;
                   6605:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6606:                   fprintf(ficgp,"\nset parametric;unset label");
                   6607:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6608:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6609:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6610:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6611: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6612:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6613:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6614:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6615:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6616:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6617:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6618:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6619:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6620:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6621:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6622:                 }else{
                   6623:                   first=0;
                   6624:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6625:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6626:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6627:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6628:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6629:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6630:                 }/* if first */
                   6631:               } /* age mod 5 */
                   6632:             } /* end loop age */
                   6633:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6634:             first=1;
                   6635:           } /*l12 */
                   6636:         } /* k12 */
                   6637:        } /*l1 */
                   6638:      }/* k1 */
                   6639:    }  /* loop on combination of covariates j1 */
                   6640:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6641:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6642:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6643:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6644:    free_vector(xp,1,npar);
                   6645:    fclose(ficresprob);
                   6646:    fclose(ficresprobcov);
                   6647:    fclose(ficresprobcor);
                   6648:    fflush(ficgp);
                   6649:    fflush(fichtmcov);
                   6650:  }
1.126     brouard  6651: 
                   6652: 
                   6653: /******************* Printing html file ***********/
1.201     brouard  6654: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6655:                  int lastpass, int stepm, int weightopt, char model[],\
                   6656:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6657:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6658:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6659:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6660:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6661: 
                   6662:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6663:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6664: </ul>");
1.237     brouard  6665:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6666: </ul>", model);
1.214     brouard  6667:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6668:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6669:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6670:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6671:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6672:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6673:    fprintf(fichtm,"\
                   6674:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6675:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6676:    fprintf(fichtm,"\
1.217     brouard  6677:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6678:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6679:    fprintf(fichtm,"\
1.126     brouard  6680:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6681:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6682:    fprintf(fichtm,"\
1.217     brouard  6683:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6684:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6685:    fprintf(fichtm,"\
1.211     brouard  6686:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6687:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6688:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6689:    if(prevfcast==1){
                   6690:      fprintf(fichtm,"\
                   6691:  - Prevalence projections by age and states:                           \
1.201     brouard  6692:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6693:    }
1.126     brouard  6694: 
                   6695: 
1.225     brouard  6696:    m=pow(2,cptcoveff);
1.222     brouard  6697:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6698: 
1.264     brouard  6699:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6700: 
                   6701:    jj1=0;
                   6702: 
                   6703:    fprintf(fichtm," \n<ul>");
                   6704:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6705:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6706:      if(m != 1 && TKresult[nres]!= k1)
                   6707:        continue;
                   6708:      jj1++;
                   6709:      if (cptcovn > 0) {
                   6710:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6711:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6712:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6713:        }
                   6714:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6715:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6716:        }
                   6717:        fprintf(fichtm,"\">");
                   6718:        
                   6719:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6720:        fprintf(fichtm,"************ Results for covariates");
                   6721:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6722:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6723:        }
                   6724:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6725:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6726:        }
                   6727:        if(invalidvarcomb[k1]){
                   6728:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6729:         continue;
                   6730:        }
                   6731:        fprintf(fichtm,"</a></li>");
                   6732:      } /* cptcovn >0 */
                   6733:    }
                   6734:      fprintf(fichtm," \n</ul>");
                   6735: 
1.222     brouard  6736:    jj1=0;
1.237     brouard  6737: 
                   6738:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6739:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6740:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6741:        continue;
1.220     brouard  6742: 
1.222     brouard  6743:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6744:      jj1++;
                   6745:      if (cptcovn > 0) {
1.264     brouard  6746:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6747:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6748:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6749:        }
                   6750:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6751:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6752:        }
                   6753:        fprintf(fichtm,"\"</a>");
                   6754:  
1.222     brouard  6755:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6756:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6757:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6758:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6759:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6760:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6761:        }
1.237     brouard  6762:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6763:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6764:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6765:       }
                   6766:        
1.230     brouard  6767:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6768:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6769:        if(invalidvarcomb[k1]){
                   6770:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6771:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6772:         continue;
                   6773:        }
                   6774:      }
                   6775:      /* aij, bij */
1.259     brouard  6776:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6777: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6778:      /* Pij */
1.241     brouard  6779:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6780: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6781:      /* Quasi-incidences */
                   6782:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6783:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6784:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6785: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6786: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6787:      /* Survival functions (period) in state j */
                   6788:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6789:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6790: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6791:      }
                   6792:      /* State specific survival functions (period) */
                   6793:      for(cpt=1; cpt<=nlstate;cpt++){
                   6794:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6795:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6796:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6797:      }
                   6798:      /* Period (stable) prevalence in each health state */
                   6799:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6800:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6801: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6802:      }
                   6803:      if(backcast==1){
                   6804:        /* Period (stable) back prevalence in each health state */
                   6805:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6806:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6807: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6808:        }
1.217     brouard  6809:      }
1.222     brouard  6810:      if(prevfcast==1){
                   6811:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6812:        for(cpt=1; cpt<=nlstate;cpt++){
1.268     brouard  6813:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.258     brouard  6814: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6815:        }
                   6816:      }
1.268     brouard  6817:      if(backcast==1){
                   6818:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6819:        for(cpt=1; cpt<=nlstate;cpt++){
                   6820:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to stable (mixed) back prevalence in state %d. Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) with weights corresponding to observed prevalence  at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6821: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   6822:        }
                   6823:      }
1.220     brouard  6824:         
1.222     brouard  6825:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6826:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6827: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6828:      }
                   6829:      /* } /\* end i1 *\/ */
                   6830:    }/* End k1 */
                   6831:    fprintf(fichtm,"</ul>");
1.126     brouard  6832: 
1.222     brouard  6833:    fprintf(fichtm,"\
1.126     brouard  6834: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6835:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6836:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6837: But because parameters are usually highly correlated (a higher incidence of disability \
                   6838: and a higher incidence of recovery can give very close observed transition) it might \
                   6839: be very useful to look not only at linear confidence intervals estimated from the \
                   6840: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6841: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6842: covariance matrix of the one-step probabilities. \
                   6843: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6844: 
1.222     brouard  6845:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6846:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6847:    fprintf(fichtm,"\
1.126     brouard  6848:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6849:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6850: 
1.222     brouard  6851:    fprintf(fichtm,"\
1.126     brouard  6852:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6853:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6854:    fprintf(fichtm,"\
1.126     brouard  6855:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6856:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6857:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6858:    fprintf(fichtm,"\
1.126     brouard  6859:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6860:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6861:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6862:    fprintf(fichtm,"\
1.128     brouard  6863:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6864:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6865:    fprintf(fichtm,"\
1.128     brouard  6866:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6867:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6868:    fprintf(fichtm,"\
1.126     brouard  6869:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6870:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6871: 
                   6872: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6873: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6874: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6875: /*     <br>",fileres,fileres,fileres,fileres); */
                   6876: /*  else  */
                   6877: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6878:    fflush(fichtm);
                   6879:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6880: 
1.225     brouard  6881:    m=pow(2,cptcoveff);
1.222     brouard  6882:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6883: 
1.222     brouard  6884:    jj1=0;
1.237     brouard  6885: 
1.241     brouard  6886:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6887:    for(k1=1; k1<=m;k1++){
1.253     brouard  6888:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6889:        continue;
1.222     brouard  6890:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6891:      jj1++;
1.126     brouard  6892:      if (cptcovn > 0) {
                   6893:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6894:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6895:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6896:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6897:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6898:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6899:       }
                   6900: 
1.126     brouard  6901:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6902: 
1.222     brouard  6903:        if(invalidvarcomb[k1]){
                   6904:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6905:         continue;
                   6906:        }
1.126     brouard  6907:      }
                   6908:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6909:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6910: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6911: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6912:      }
                   6913:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6914: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6915: true period expectancies (those weighted with period prevalences are also\
                   6916:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6917:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6918: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6919:      /* } /\* end i1 *\/ */
                   6920:    }/* End k1 */
1.241     brouard  6921:   }/* End nres */
1.222     brouard  6922:    fprintf(fichtm,"</ul>");
                   6923:    fflush(fichtm);
1.126     brouard  6924: }
                   6925: 
                   6926: /******************* Gnuplot file **************/
1.270   ! brouard  6927: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6928: 
                   6929:   char dirfileres[132],optfileres[132];
1.264     brouard  6930:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6931:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6932:   int lv=0, vlv=0, kl=0;
1.130     brouard  6933:   int ng=0;
1.201     brouard  6934:   int vpopbased;
1.223     brouard  6935:   int ioffset; /* variable offset for columns */
1.270   ! brouard  6936:   int iyearc=1; /* variable column for year of projection  */
        !          6937:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  6938:   int nres=0; /* Index of resultline */
1.266     brouard  6939:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6940: 
1.126     brouard  6941: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6942: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6943: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6944: /*   } */
                   6945: 
                   6946:   /*#ifdef windows */
                   6947:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6948:   /*#endif */
1.225     brouard  6949:   m=pow(2,cptcoveff);
1.126     brouard  6950: 
1.202     brouard  6951:   /* Contribution to likelihood */
                   6952:   /* Plot the probability implied in the likelihood */
1.223     brouard  6953:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6954:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6955:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6956:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6957: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6958:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6959: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6960:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6961:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6962:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6963:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6964:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6965:   for (i=1; i<= nlstate ; i ++) {
                   6966:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6967:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6968:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6969:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6970:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6971:     }
                   6972:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6973:   }
                   6974:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6975:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6976:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6977:   fprintf(ficgp,"\nset out;unset log\n");
                   6978:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6979: 
1.126     brouard  6980:   strcpy(dirfileres,optionfilefiname);
                   6981:   strcpy(optfileres,"vpl");
1.223     brouard  6982:   /* 1eme*/
1.238     brouard  6983:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6984:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6985:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6986:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6987:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6988:          continue;
                   6989:        /* We are interested in selected combination by the resultline */
1.246     brouard  6990:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6991:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  6992:        strcpy(gplotlabel,"(");
1.238     brouard  6993:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6994:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6995:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6996:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6997:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6998:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6999:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7000:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7001:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7002:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7003:        }
                   7004:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7005:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7006:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7007:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7008:        }
                   7009:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7010:        /* printf("\n#\n"); */
1.238     brouard  7011:        fprintf(ficgp,"\n#\n");
                   7012:        if(invalidvarcomb[k1]){
1.260     brouard  7013:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7014:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7015:          continue;
                   7016:        }
1.235     brouard  7017:       
1.241     brouard  7018:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7019:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7020:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7021:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7022:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7023:       /* k1-1 error should be nres-1*/
1.238     brouard  7024:        for (i=1; i<= nlstate ; i ++) {
                   7025:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7026:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7027:        }
1.260     brouard  7028:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7029:        for (i=1; i<= nlstate ; i ++) {
                   7030:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7031:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7032:        } 
1.260     brouard  7033:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7034:        for (i=1; i<= nlstate ; i ++) {
                   7035:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7036:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7037:        }  
1.265     brouard  7038:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7039:        
                   7040:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7041:         if(cptcoveff ==0){
                   7042:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+(cpt-1),  cpt );
                   7043:        }else{
                   7044:          kl=0;
                   7045:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7046:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7047:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7048:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7049:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7050:            vlv= nbcode[Tvaraff[k]][lv];
                   7051:            kl++;
                   7052:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7053:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7054:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7055:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7056:            if(k==cptcoveff){
                   7057:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7058:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7059:            }else{
                   7060:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7061:              kl++;
                   7062:            }
                   7063:          } /* end covariate */
                   7064:        } /* end if no covariate */
                   7065: 
1.238     brouard  7066:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7067:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7068:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7069:          if(cptcoveff ==0){
1.245     brouard  7070:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7071:          }else{
                   7072:            kl=0;
                   7073:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7074:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7075:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7076:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7077:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7078:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7079:              kl++;
1.238     brouard  7080:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7081:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7082:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7083:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7084:              if(k==cptcoveff){
1.245     brouard  7085:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7086:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7087:              }else{
                   7088:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7089:                kl++;
                   7090:              }
                   7091:            } /* end covariate */
                   7092:          } /* end if no covariate */
1.268     brouard  7093:          if(backcast == 1){
                   7094:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7095:            /* k1-1 error should be nres-1*/
                   7096:            for (i=1; i<= nlstate ; i ++) {
                   7097:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7098:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7099:            }
                   7100:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7101:            for (i=1; i<= nlstate ; i ++) {
                   7102:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7103:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7104:            } 
                   7105:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
                   7106:            for (i=1; i<= nlstate ; i ++) {
                   7107:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7108:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7109:            } 
                   7110:            fprintf(ficgp,"\" t\"\" w l lt 1");
                   7111:          } /* end if backprojcast */
1.238     brouard  7112:        } /* end if backcast */
1.264     brouard  7113:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7114:       } /* nres */
1.201     brouard  7115:     } /* k1 */
                   7116:   } /* cpt */
1.235     brouard  7117: 
                   7118:   
1.126     brouard  7119:   /*2 eme*/
1.238     brouard  7120:   for (k1=1; k1<= m ; k1 ++){  
                   7121:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7122:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7123:        continue;
                   7124:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7125:       strcpy(gplotlabel,"(");
1.238     brouard  7126:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7127:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7128:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7129:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7130:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7131:        vlv= nbcode[Tvaraff[k]][lv];
                   7132:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7133:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7134:       }
1.237     brouard  7135:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7136:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7137:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7138:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7139:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7140:       }
1.264     brouard  7141:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7142:       fprintf(ficgp,"\n#\n");
1.223     brouard  7143:       if(invalidvarcomb[k1]){
                   7144:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7145:        continue;
                   7146:       }
1.219     brouard  7147:                        
1.241     brouard  7148:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7149:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7150:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7151:        if(vpopbased==0){
1.238     brouard  7152:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7153:        }else
1.238     brouard  7154:          fprintf(ficgp,"\nreplot ");
                   7155:        for (i=1; i<= nlstate+1 ; i ++) {
                   7156:          k=2*i;
1.261     brouard  7157:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7158:          for (j=1; j<= nlstate+1 ; j ++) {
                   7159:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7160:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7161:          }   
                   7162:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7163:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7164:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7165:          for (j=1; j<= nlstate+1 ; j ++) {
                   7166:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7167:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7168:          }   
                   7169:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7170:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7171:          for (j=1; j<= nlstate+1 ; j ++) {
                   7172:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7173:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7174:          }   
                   7175:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7176:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7177:        } /* state */
                   7178:       } /* vpopbased */
1.264     brouard  7179:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7180:     } /* end nres */
                   7181:   } /* k1 end 2 eme*/
                   7182:        
                   7183:        
                   7184:   /*3eme*/
                   7185:   for (k1=1; k1<= m ; k1 ++){
                   7186:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7187:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7188:        continue;
                   7189: 
                   7190:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7191:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7192:        strcpy(gplotlabel,"(");
1.238     brouard  7193:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7194:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7195:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7196:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7197:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7198:          vlv= nbcode[Tvaraff[k]][lv];
                   7199:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7200:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7201:        }
                   7202:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7203:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7204:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7205:        }       
1.264     brouard  7206:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7207:        fprintf(ficgp,"\n#\n");
                   7208:        if(invalidvarcomb[k1]){
                   7209:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7210:          continue;
                   7211:        }
                   7212:                        
                   7213:        /*       k=2+nlstate*(2*cpt-2); */
                   7214:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7215:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7216:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7217:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7218: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7219:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7220:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7221:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7222:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7223:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7224:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7225:                                
1.238     brouard  7226:        */
                   7227:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7228:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7229:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7230:                                
1.238     brouard  7231:        } 
1.261     brouard  7232:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7233:       }
1.264     brouard  7234:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7235:     } /* end nres */
                   7236:   } /* end kl 3eme */
1.126     brouard  7237:   
1.223     brouard  7238:   /* 4eme */
1.201     brouard  7239:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7240:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7241:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7242:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7243:        continue;
1.238     brouard  7244:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7245:        strcpy(gplotlabel,"(");
1.238     brouard  7246:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7247:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7248:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7249:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7250:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7251:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7252:          vlv= nbcode[Tvaraff[k]][lv];
                   7253:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7254:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7255:        }
                   7256:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7257:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7258:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7259:        }       
1.264     brouard  7260:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7261:        fprintf(ficgp,"\n#\n");
                   7262:        if(invalidvarcomb[k1]){
                   7263:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7264:          continue;
1.223     brouard  7265:        }
1.238     brouard  7266:       
1.241     brouard  7267:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7268:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7269:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7270: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7271:        k=3;
                   7272:        for (i=1; i<= nlstate ; i ++){
                   7273:          if(i==1){
                   7274:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7275:          }else{
                   7276:            fprintf(ficgp,", '' ");
                   7277:          }
                   7278:          l=(nlstate+ndeath)*(i-1)+1;
                   7279:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7280:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7281:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7282:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7283:        } /* nlstate */
1.264     brouard  7284:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7285:       } /* end cpt state*/ 
                   7286:     } /* end nres */
                   7287:   } /* end covariate k1 */  
                   7288: 
1.220     brouard  7289: /* 5eme */
1.201     brouard  7290:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7291:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7292:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7293:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7294:        continue;
1.238     brouard  7295:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7296:        strcpy(gplotlabel,"(");
1.238     brouard  7297:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7298:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7299:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7300:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7301:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7302:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7303:          vlv= nbcode[Tvaraff[k]][lv];
                   7304:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7305:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7306:        }
                   7307:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7308:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7309:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7310:        }       
1.264     brouard  7311:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7312:        fprintf(ficgp,"\n#\n");
                   7313:        if(invalidvarcomb[k1]){
                   7314:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7315:          continue;
                   7316:        }
1.227     brouard  7317:       
1.241     brouard  7318:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7319:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7320:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7321: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7322:        k=3;
                   7323:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7324:          if(j==1)
                   7325:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7326:          else
                   7327:            fprintf(ficgp,", '' ");
                   7328:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7329:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7330:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7331:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7332:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7333:        } /* nlstate */
                   7334:        fprintf(ficgp,", '' ");
                   7335:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7336:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7337:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7338:          if(j < nlstate)
                   7339:            fprintf(ficgp,"$%d +",k+l);
                   7340:          else
                   7341:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7342:        }
1.264     brouard  7343:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7344:       } /* end cpt state*/ 
                   7345:     } /* end covariate */  
                   7346:   } /* end nres */
1.227     brouard  7347:   
1.220     brouard  7348: /* 6eme */
1.202     brouard  7349:   /* CV preval stable (period) for each covariate */
1.237     brouard  7350:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7351:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7352:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7353:       continue;
1.255     brouard  7354:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7355:       strcpy(gplotlabel,"(");      
1.211     brouard  7356:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7357:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7358:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7359:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7360:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7361:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7362:        vlv= nbcode[Tvaraff[k]][lv];
                   7363:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7364:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7365:       }
1.237     brouard  7366:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7367:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7368:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7369:       }        
1.264     brouard  7370:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7371:       fprintf(ficgp,"\n#\n");
1.223     brouard  7372:       if(invalidvarcomb[k1]){
1.227     brouard  7373:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7374:        continue;
1.223     brouard  7375:       }
1.227     brouard  7376:       
1.241     brouard  7377:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7378:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7379:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7380: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7381:       k=3; /* Offset */
1.255     brouard  7382:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7383:        if(i==1)
                   7384:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7385:        else
                   7386:          fprintf(ficgp,", '' ");
1.255     brouard  7387:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7388:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7389:        for (j=2; j<= nlstate ; j ++)
                   7390:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7391:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7392:       } /* nlstate */
1.264     brouard  7393:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7394:     } /* end cpt state*/ 
                   7395:   } /* end covariate */  
1.227     brouard  7396:   
                   7397:   
1.220     brouard  7398: /* 7eme */
1.218     brouard  7399:   if(backcast == 1){
1.217     brouard  7400:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7401:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7402:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7403:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7404:        continue;
1.268     brouard  7405:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7406:        strcpy(gplotlabel,"(");      
                   7407:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7408:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7409:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7410:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7411:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7412:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7413:          vlv= nbcode[Tvaraff[k]][lv];
                   7414:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7415:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7416:        }
1.237     brouard  7417:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7418:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7419:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7420:        }       
1.264     brouard  7421:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7422:        fprintf(ficgp,"\n#\n");
                   7423:        if(invalidvarcomb[k1]){
                   7424:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7425:          continue;
                   7426:        }
                   7427:        
1.241     brouard  7428:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7429:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7430:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7431: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7432:        k=3; /* Offset */
1.268     brouard  7433:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7434:          if(i==1)
                   7435:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7436:          else
                   7437:            fprintf(ficgp,", '' ");
                   7438:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7439:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7440:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7441:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7442:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7443:          /* for (j=2; j<= nlstate ; j ++) */
                   7444:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7445:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7446:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7447:        } /* nlstate */
1.264     brouard  7448:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7449:       } /* end cpt state*/ 
                   7450:     } /* end covariate */  
                   7451:   } /* End if backcast */
                   7452:   
1.223     brouard  7453:   /* 8eme */
1.218     brouard  7454:   if(prevfcast==1){
                   7455:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7456:     
1.237     brouard  7457:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7458:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7459:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7460:        continue;
1.211     brouard  7461:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7462:        strcpy(gplotlabel,"(");      
1.227     brouard  7463:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7464:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7465:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7466:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7467:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7468:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7469:          vlv= nbcode[Tvaraff[k]][lv];
                   7470:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7471:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7472:        }
1.237     brouard  7473:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7474:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7475:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7476:        }       
1.264     brouard  7477:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7478:        fprintf(ficgp,"\n#\n");
                   7479:        if(invalidvarcomb[k1]){
                   7480:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7481:          continue;
                   7482:        }
                   7483:        
                   7484:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7485:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7486:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7487:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7488: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7489: 
                   7490:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7491:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7492:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7493:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7494:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7495:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7496:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7497:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7498:          if(i==istart){
1.227     brouard  7499:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7500:          }else{
                   7501:            fprintf(ficgp,",\\\n '' ");
                   7502:          }
                   7503:          if(cptcoveff ==0){ /* No covariate */
                   7504:            ioffset=2; /* Age is in 2 */
                   7505:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7506:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7507:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7508:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7509:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7510:            if(i==nlstate+1){
1.270   ! brouard  7511:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7512:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7513:              fprintf(ficgp,",\\\n '' ");
                   7514:              fprintf(ficgp," u %d:(",ioffset); 
1.270   ! brouard  7515:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7516:                     offyear,                           \
1.268     brouard  7517:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7518:            }else
1.227     brouard  7519:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7520:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7521:          }else{ /* more than 2 covariates */
1.270   ! brouard  7522:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
        !          7523:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
        !          7524:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
        !          7525:            iyearc=ioffset-1;
        !          7526:            iagec=ioffset;
1.227     brouard  7527:            fprintf(ficgp," u %d:(",ioffset); 
                   7528:            kl=0;
                   7529:            strcpy(gplotcondition,"(");
                   7530:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7531:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7532:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7533:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7534:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7535:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7536:              kl++;
                   7537:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7538:              kl++;
                   7539:              if(k <cptcoveff && cptcoveff>1)
                   7540:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7541:            }
                   7542:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7543:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7544:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7545:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7546:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7547:            if(i==nlstate+1){
1.270   ! brouard  7548:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
        !          7549:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7550:              fprintf(ficgp,",\\\n '' ");
1.270   ! brouard  7551:              fprintf(ficgp," u %d:(",iagec); 
        !          7552:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
        !          7553:                      iyearc, iagec, offyear,                           \
        !          7554:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7555: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7556:            }else{
                   7557:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7558:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7559:            }
                   7560:          } /* end if covariate */
                   7561:        } /* nlstate */
1.264     brouard  7562:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7563:       } /* end cpt state*/
                   7564:     } /* end covariate */
                   7565:   } /* End if prevfcast */
1.227     brouard  7566:   
1.268     brouard  7567:   if(backcast==1){
                   7568:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7569:     
                   7570:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7571:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7572:       if(m != 1 && TKresult[nres]!= k1)
                   7573:        continue;
                   7574:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7575:        strcpy(gplotlabel,"(");      
                   7576:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7577:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7578:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7579:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7580:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7581:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7582:          vlv= nbcode[Tvaraff[k]][lv];
                   7583:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7584:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7585:        }
                   7586:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7587:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7588:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7589:        }       
                   7590:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7591:        fprintf(ficgp,"\n#\n");
                   7592:        if(invalidvarcomb[k1]){
                   7593:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7594:          continue;
                   7595:        }
                   7596:        
                   7597:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7598:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7599:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7600:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7601: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7602: 
                   7603:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7604:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7605:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7606:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7607:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7608:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7609:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7610:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7611:          if(i==istart){
                   7612:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7613:          }else{
                   7614:            fprintf(ficgp,",\\\n '' ");
                   7615:          }
                   7616:          if(cptcoveff ==0){ /* No covariate */
                   7617:            ioffset=2; /* Age is in 2 */
                   7618:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7619:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7620:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7621:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7622:            fprintf(ficgp," u %d:(", ioffset); 
                   7623:            if(i==nlstate+1){
1.270   ! brouard  7624:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7625:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7626:              fprintf(ficgp,",\\\n '' ");
                   7627:              fprintf(ficgp," u %d:(",ioffset); 
1.270   ! brouard  7628:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7629:                     offbyear,                          \
                   7630:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7631:            }else
                   7632:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7633:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7634:          }else{ /* more than 2 covariates */
1.270   ! brouard  7635:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
        !          7636:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
        !          7637:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
        !          7638:            iyearc=ioffset-1;
        !          7639:            iagec=ioffset;
1.268     brouard  7640:            fprintf(ficgp," u %d:(",ioffset); 
                   7641:            kl=0;
                   7642:            strcpy(gplotcondition,"(");
                   7643:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7644:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7645:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7646:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7647:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7648:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7649:              kl++;
                   7650:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7651:              kl++;
                   7652:              if(k <cptcoveff && cptcoveff>1)
                   7653:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7654:            }
                   7655:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7656:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7657:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7658:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7659:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7660:            if(i==nlstate+1){
1.270   ! brouard  7661:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
        !          7662:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7663:              fprintf(ficgp,",\\\n '' ");
1.270   ! brouard  7664:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7665:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270   ! brouard  7666:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
        !          7667:                      iyearc,iagec,offbyear,                            \
        !          7668:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7669: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7670:            }else{
                   7671:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7672:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7673:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7674:            }
                   7675:          } /* end if covariate */
                   7676:        } /* nlstate */
                   7677:        fprintf(ficgp,"\nset out; unset label;\n");
                   7678:       } /* end cpt state*/
                   7679:     } /* end covariate */
                   7680:   } /* End if backcast */
                   7681:   
1.227     brouard  7682:   
1.238     brouard  7683:   /* 9eme writing MLE parameters */
                   7684:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7685:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7686:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7687:     for(k=1; k <=(nlstate+ndeath); k++){
                   7688:       if (k != i) {
1.227     brouard  7689:        fprintf(ficgp,"#   current state %d\n",k);
                   7690:        for(j=1; j <=ncovmodel; j++){
                   7691:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7692:          jk++; 
                   7693:        }
                   7694:        fprintf(ficgp,"\n");
1.126     brouard  7695:       }
                   7696:     }
1.223     brouard  7697:   }
1.187     brouard  7698:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7699:   
1.145     brouard  7700:   /*goto avoid;*/
1.238     brouard  7701:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7702:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7703:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7704:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7705:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7706:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7707:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7708:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7709:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7710:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7711:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7712:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7713:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7714:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7715:   fprintf(ficgp,"#\n");
1.223     brouard  7716:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7717:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7718:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7719:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7720:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7721:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7722:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7723:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7724:        continue;
1.264     brouard  7725:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7726:       strcpy(gplotlabel,"(");
                   7727:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7728:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7729:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7730:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7731:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7732:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7733:        vlv= nbcode[Tvaraff[k]][lv];
                   7734:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7735:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7736:       }
1.237     brouard  7737:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7738:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7739:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7740:       }        
1.264     brouard  7741:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7742:       fprintf(ficgp,"\n#\n");
1.264     brouard  7743:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7744:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7745:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7746:       if (ng==1){
                   7747:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7748:        fprintf(ficgp,"\nunset log y");
                   7749:       }else if (ng==2){
                   7750:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7751:        fprintf(ficgp,"\nset log y");
                   7752:       }else if (ng==3){
                   7753:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7754:        fprintf(ficgp,"\nset log y");
                   7755:       }else
                   7756:        fprintf(ficgp,"\nunset title ");
                   7757:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7758:       i=1;
                   7759:       for(k2=1; k2<=nlstate; k2++) {
                   7760:        k3=i;
                   7761:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7762:          if (k != k2){
                   7763:            switch( ng) {
                   7764:            case 1:
                   7765:              if(nagesqr==0)
                   7766:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7767:              else /* nagesqr =1 */
                   7768:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7769:              break;
                   7770:            case 2: /* ng=2 */
                   7771:              if(nagesqr==0)
                   7772:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7773:              else /* nagesqr =1 */
                   7774:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7775:              break;
                   7776:            case 3:
                   7777:              if(nagesqr==0)
                   7778:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7779:              else /* nagesqr =1 */
                   7780:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7781:              break;
                   7782:            }
                   7783:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7784:            ijp=1; /* product no age */
                   7785:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7786:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7787:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7788:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7789:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7790:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7791:                    if(DummyV[j]==0){
                   7792:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7793:                    }else{ /* quantitative */
                   7794:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7795:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7796:                    }
                   7797:                    ij++;
1.237     brouard  7798:                  }
1.268     brouard  7799:                } 
                   7800:              }else if(cptcovprod >0){
                   7801:                if(j==Tprod[ijp]) { /* */ 
                   7802:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7803:                  if(ijp <=cptcovprod) { /* Product */
                   7804:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7805:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7806:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7807:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7808:                      }else{ /* Vn is dummy and Vm is quanti */
                   7809:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7810:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7811:                      }
                   7812:                    }else{ /* Vn*Vm Vn is quanti */
                   7813:                      if(DummyV[Tvard[ijp][2]]==0){
                   7814:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7815:                      }else{ /* Both quanti */
                   7816:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7817:                      }
1.237     brouard  7818:                    }
1.268     brouard  7819:                    ijp++;
1.237     brouard  7820:                  }
1.268     brouard  7821:                } /* end Tprod */
1.237     brouard  7822:              } else{  /* simple covariate */
1.264     brouard  7823:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7824:                if(Dummy[j]==0){
                   7825:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7826:                }else{ /* quantitative */
                   7827:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7828:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7829:                }
1.237     brouard  7830:              } /* end simple */
                   7831:            } /* end j */
1.223     brouard  7832:          }else{
                   7833:            i=i-ncovmodel;
                   7834:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7835:              fprintf(ficgp," (1.");
                   7836:          }
1.227     brouard  7837:          
1.223     brouard  7838:          if(ng != 1){
                   7839:            fprintf(ficgp,")/(1");
1.227     brouard  7840:            
1.264     brouard  7841:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7842:              if(nagesqr==0)
1.264     brouard  7843:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7844:              else /* nagesqr =1 */
1.264     brouard  7845:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7846:               
1.223     brouard  7847:              ij=1;
                   7848:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7849:                 if(cptcovage >0){ 
                   7850:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7851:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7852:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7853:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7854:                       ij++;
                   7855:                     }
                   7856:                   }
                   7857:                 }else
                   7858:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7859:              }
                   7860:              fprintf(ficgp,")");
                   7861:            }
                   7862:            fprintf(ficgp,")");
                   7863:            if(ng ==2)
                   7864:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7865:            else /* ng= 3 */
                   7866:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7867:          }else{ /* end ng <> 1 */
                   7868:            if( k !=k2) /* logit p11 is hard to draw */
                   7869:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7870:          }
                   7871:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7872:            fprintf(ficgp,",");
                   7873:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7874:            fprintf(ficgp,",");
                   7875:          i=i+ncovmodel;
                   7876:        } /* end k */
                   7877:       } /* end k2 */
1.264     brouard  7878:       fprintf(ficgp,"\n set out; unset label;\n");
                   7879:     } /* end k1 */
1.223     brouard  7880:   } /* end ng */
                   7881:   /* avoid: */
                   7882:   fflush(ficgp); 
1.126     brouard  7883: }  /* end gnuplot */
                   7884: 
                   7885: 
                   7886: /*************** Moving average **************/
1.219     brouard  7887: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7888:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7889:    
1.222     brouard  7890:    int i, cpt, cptcod;
                   7891:    int modcovmax =1;
                   7892:    int mobilavrange, mob;
                   7893:    int iage=0;
                   7894: 
1.266     brouard  7895:    double sum=0., sumr=0.;
1.222     brouard  7896:    double age;
1.266     brouard  7897:    double *sumnewp, *sumnewm, *sumnewmr;
                   7898:    double *agemingood, *agemaxgood; 
                   7899:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7900:   
                   7901:   
1.225     brouard  7902:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7903:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7904: 
                   7905:    sumnewp = vector(1,ncovcombmax);
                   7906:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7907:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7908:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7909:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7910:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7911:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7912: 
                   7913:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7914:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7915:      sumnewp[cptcod]=0.;
1.266     brouard  7916:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7917:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7918:    }
                   7919:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7920:   
1.266     brouard  7921:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7922:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7923:      else mobilavrange=mobilav;
                   7924:      for (age=bage; age<=fage; age++)
                   7925:        for (i=1; i<=nlstate;i++)
                   7926:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7927:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7928:      /* We keep the original values on the extreme ages bage, fage and for 
                   7929:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7930:        we use a 5 terms etc. until the borders are no more concerned. 
                   7931:      */ 
                   7932:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7933:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7934:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7935:           sumnewm[cptcod]=0.;
                   7936:           for (i=1; i<=nlstate;i++){
1.222     brouard  7937:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7938:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7939:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7940:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7941:             }
                   7942:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7943:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7944:           } /* end i */
                   7945:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7946:         } /* end cptcod */
1.222     brouard  7947:        }/* end age */
                   7948:      }/* end mob */
1.266     brouard  7949:    }else{
                   7950:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7951:      return -1;
1.266     brouard  7952:    }
                   7953: 
                   7954:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7955:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7956:      if(invalidvarcomb[cptcod]){
                   7957:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7958:        continue;
                   7959:      }
1.219     brouard  7960: 
1.266     brouard  7961:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7962:        sumnewm[cptcod]=0.;
                   7963:        sumnewmr[cptcod]=0.;
                   7964:        for (i=1; i<=nlstate;i++){
                   7965:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7966:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7967:        }
                   7968:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7969:         agemingoodr[cptcod]=age;
                   7970:        }
                   7971:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7972:           agemingood[cptcod]=age;
                   7973:        }
                   7974:      } /* age */
                   7975:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  7976:        sumnewm[cptcod]=0.;
1.266     brouard  7977:        sumnewmr[cptcod]=0.;
1.222     brouard  7978:        for (i=1; i<=nlstate;i++){
                   7979:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  7980:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7981:        }
                   7982:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7983:         agemaxgoodr[cptcod]=age;
1.222     brouard  7984:        }
                   7985:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  7986:         agemaxgood[cptcod]=age;
                   7987:        }
                   7988:      } /* age */
                   7989:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   7990:      /* but they will change */
                   7991:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   7992:        sumnewm[cptcod]=0.;
                   7993:        sumnewmr[cptcod]=0.;
                   7994:        for (i=1; i<=nlstate;i++){
                   7995:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7996:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7997:        }
                   7998:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   7999:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8000:           agemaxgoodr[cptcod]=age;  /* age min */
                   8001:           for (i=1; i<=nlstate;i++)
                   8002:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8003:         }else{ /* bad we change the value with the values of good ages */
                   8004:           for (i=1; i<=nlstate;i++){
                   8005:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8006:           } /* i */
                   8007:         } /* end bad */
                   8008:        }else{
                   8009:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8010:           agemaxgood[cptcod]=age;
                   8011:         }else{ /* bad we change the value with the values of good ages */
                   8012:           for (i=1; i<=nlstate;i++){
                   8013:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8014:           } /* i */
                   8015:         } /* end bad */
                   8016:        }/* end else */
                   8017:        sum=0.;sumr=0.;
                   8018:        for (i=1; i<=nlstate;i++){
                   8019:         sum+=mobaverage[(int)age][i][cptcod];
                   8020:         sumr+=probs[(int)age][i][cptcod];
                   8021:        }
                   8022:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8023:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8024:        } /* end bad */
                   8025:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8026:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8027:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8028:        } /* end bad */
                   8029:      }/* age */
1.266     brouard  8030: 
                   8031:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8032:        sumnewm[cptcod]=0.;
1.266     brouard  8033:        sumnewmr[cptcod]=0.;
1.222     brouard  8034:        for (i=1; i<=nlstate;i++){
                   8035:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8036:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8037:        } 
                   8038:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8039:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8040:           agemingoodr[cptcod]=age;
                   8041:           for (i=1; i<=nlstate;i++)
                   8042:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8043:         }else{ /* bad we change the value with the values of good ages */
                   8044:           for (i=1; i<=nlstate;i++){
                   8045:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8046:           } /* i */
                   8047:         } /* end bad */
                   8048:        }else{
                   8049:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8050:           agemingood[cptcod]=age;
                   8051:         }else{ /* bad */
                   8052:           for (i=1; i<=nlstate;i++){
                   8053:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8054:           } /* i */
                   8055:         } /* end bad */
                   8056:        }/* end else */
                   8057:        sum=0.;sumr=0.;
                   8058:        for (i=1; i<=nlstate;i++){
                   8059:         sum+=mobaverage[(int)age][i][cptcod];
                   8060:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8061:        }
1.266     brouard  8062:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8063:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8064:        } /* end bad */
                   8065:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8066:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8067:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8068:        } /* end bad */
                   8069:      }/* age */
1.266     brouard  8070: 
1.222     brouard  8071:                
                   8072:      for (age=bage; age<=fage; age++){
1.235     brouard  8073:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8074:        sumnewp[cptcod]=0.;
                   8075:        sumnewm[cptcod]=0.;
                   8076:        for (i=1; i<=nlstate;i++){
                   8077:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8078:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8079:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8080:        }
                   8081:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8082:      }
                   8083:      /* printf("\n"); */
                   8084:      /* } */
1.266     brouard  8085: 
1.222     brouard  8086:      /* brutal averaging */
1.266     brouard  8087:      /* for (i=1; i<=nlstate;i++){ */
                   8088:      /*   for (age=1; age<=bage; age++){ */
                   8089:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8090:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8091:      /*   }     */
                   8092:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8093:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8094:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8095:      /*   } */
                   8096:      /* } /\* end i status *\/ */
                   8097:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8098:      /*   for (age=1; age<=AGESUP; age++){ */
                   8099:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8100:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8101:      /*   } */
                   8102:      /* } */
1.222     brouard  8103:    }/* end cptcod */
1.266     brouard  8104:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8105:    free_vector(agemaxgood,1, ncovcombmax);
                   8106:    free_vector(agemingood,1, ncovcombmax);
                   8107:    free_vector(agemingoodr,1, ncovcombmax);
                   8108:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8109:    free_vector(sumnewm,1, ncovcombmax);
                   8110:    free_vector(sumnewp,1, ncovcombmax);
                   8111:    return 0;
                   8112:  }/* End movingaverage */
1.218     brouard  8113:  
1.126     brouard  8114: 
                   8115: /************** Forecasting ******************/
1.269     brouard  8116:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8117:   /* proj1, year, month, day of starting projection 
                   8118:      agemin, agemax range of age
                   8119:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8120:      anproj2 year of en of projection (same day and month as proj1).
                   8121:   */
1.267     brouard  8122:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8123:   double agec; /* generic age */
                   8124:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8125:   double *popeffectif,*popcount;
                   8126:   double ***p3mat;
1.218     brouard  8127:   /* double ***mobaverage; */
1.126     brouard  8128:   char fileresf[FILENAMELENGTH];
                   8129: 
                   8130:   agelim=AGESUP;
1.211     brouard  8131:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8132:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8133:      We still use firstpass and lastpass as another selection.
                   8134:   */
1.214     brouard  8135:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8136:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8137:  
1.201     brouard  8138:   strcpy(fileresf,"F_"); 
                   8139:   strcat(fileresf,fileresu);
1.126     brouard  8140:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8141:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8142:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8143:   }
1.235     brouard  8144:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8145:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8146: 
1.225     brouard  8147:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8148: 
                   8149: 
                   8150:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8151:   if (stepm<=12) stepsize=1;
                   8152:   if(estepm < stepm){
                   8153:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8154:   }
1.270   ! brouard  8155:   else{
        !          8156:     hstepm=estepm;   
        !          8157:   }
        !          8158:   if(estepm > stepm){ /* Yes every two year */
        !          8159:     stepsize=2;
        !          8160:   }
1.126     brouard  8161: 
                   8162:   hstepm=hstepm/stepm; 
                   8163:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8164:                                fractional in yp1 */
                   8165:   anprojmean=yp;
                   8166:   yp2=modf((yp1*12),&yp);
                   8167:   mprojmean=yp;
                   8168:   yp1=modf((yp2*30.5),&yp);
                   8169:   jprojmean=yp;
                   8170:   if(jprojmean==0) jprojmean=1;
                   8171:   if(mprojmean==0) jprojmean=1;
                   8172: 
1.227     brouard  8173:   i1=pow(2,cptcoveff);
1.126     brouard  8174:   if (cptcovn < 1){i1=1;}
                   8175:   
                   8176:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8177:   
                   8178:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8179:   
1.126     brouard  8180: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8181:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8182:   for(k=1; k<=i1;k++){
1.253     brouard  8183:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8184:       continue;
1.227     brouard  8185:     if(invalidvarcomb[k]){
                   8186:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8187:       continue;
                   8188:     }
                   8189:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8190:     for(j=1;j<=cptcoveff;j++) {
                   8191:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8192:     }
1.235     brouard  8193:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8194:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8195:     }
1.227     brouard  8196:     fprintf(ficresf," yearproj age");
                   8197:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8198:       for(i=1; i<=nlstate;i++)               
                   8199:        fprintf(ficresf," p%d%d",i,j);
                   8200:       fprintf(ficresf," wp.%d",j);
                   8201:     }
                   8202:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8203:       fprintf(ficresf,"\n");
                   8204:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270   ! brouard  8205:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
        !          8206:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8207:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8208:        nhstepm = nhstepm/hstepm; 
                   8209:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8210:        oldm=oldms;savm=savms;
1.268     brouard  8211:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8212:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8213:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8214:        for (h=0; h<=nhstepm; h++){
                   8215:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8216:            break;
                   8217:          }
                   8218:        }
                   8219:        fprintf(ficresf,"\n");
                   8220:        for(j=1;j<=cptcoveff;j++) 
                   8221:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8222:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8223:        
                   8224:        for(j=1; j<=nlstate+ndeath;j++) {
                   8225:          ppij=0.;
                   8226:          for(i=1; i<=nlstate;i++) {
                   8227:            /* if (mobilav>=1)  */
1.269     brouard  8228:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8229:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8230:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8231:            /* } */
                   8232:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8233:          } /* end i */
                   8234:          fprintf(ficresf," %.3f", ppij);
                   8235:        }/* end j */
1.227     brouard  8236:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8237:       } /* end agec */
1.266     brouard  8238:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8239:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8240:     } /* end yearp */
                   8241:   } /* end  k */
1.219     brouard  8242:        
1.126     brouard  8243:   fclose(ficresf);
1.215     brouard  8244:   printf("End of Computing forecasting \n");
                   8245:   fprintf(ficlog,"End of Computing forecasting\n");
                   8246: 
1.126     brouard  8247: }
                   8248: 
1.269     brouard  8249: /************** Back Forecasting ******************/
                   8250:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8251:   /* back1, year, month, day of starting backection
                   8252:      agemin, agemax range of age
                   8253:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8254:      anback2 year of end of backprojection (same day and month as back1).
                   8255:      prevacurrent and prev are prevalences.
1.267     brouard  8256:   */
                   8257:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8258:   double agec; /* generic age */
1.268     brouard  8259:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8260:   double *popeffectif,*popcount;
                   8261:   double ***p3mat;
                   8262:   /* double ***mobaverage; */
                   8263:   char fileresfb[FILENAMELENGTH];
                   8264:  
1.268     brouard  8265:   agelim=AGEINF;
1.267     brouard  8266:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8267:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8268:      We still use firstpass and lastpass as another selection.
                   8269:   */
                   8270:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8271:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8272: 
                   8273:   /*Do we need to compute prevalence again?*/
                   8274: 
                   8275:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8276:   
                   8277:   strcpy(fileresfb,"FB_");
                   8278:   strcat(fileresfb,fileresu);
                   8279:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8280:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8281:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8282:   }
                   8283:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8284:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8285:   
                   8286:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8287:   
                   8288:    
                   8289:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8290:   if (stepm<=12) stepsize=1;
                   8291:   if(estepm < stepm){
                   8292:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8293:   }
1.270   ! brouard  8294:   else{
        !          8295:     hstepm=estepm;   
        !          8296:   }
        !          8297:   if(estepm >= stepm){ /* Yes every two year */
        !          8298:     stepsize=2;
        !          8299:   }
1.267     brouard  8300:   
                   8301:   hstepm=hstepm/stepm;
                   8302:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8303:                                fractional in yp1 */
                   8304:   anprojmean=yp;
                   8305:   yp2=modf((yp1*12),&yp);
                   8306:   mprojmean=yp;
                   8307:   yp1=modf((yp2*30.5),&yp);
                   8308:   jprojmean=yp;
                   8309:   if(jprojmean==0) jprojmean=1;
                   8310:   if(mprojmean==0) jprojmean=1;
                   8311:   
                   8312:   i1=pow(2,cptcoveff);
                   8313:   if (cptcovn < 1){i1=1;}
                   8314:   
                   8315:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8316:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8317:   
                   8318:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8319:   
                   8320:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8321:   for(k=1; k<=i1;k++){
                   8322:     if(i1 != 1 && TKresult[nres]!= k)
                   8323:       continue;
                   8324:     if(invalidvarcomb[k]){
                   8325:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8326:       continue;
                   8327:     }
1.268     brouard  8328:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8329:     for(j=1;j<=cptcoveff;j++) {
                   8330:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8331:     }
                   8332:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8333:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8334:     }
                   8335:     fprintf(ficresfb," yearbproj age");
                   8336:     for(j=1; j<=nlstate+ndeath;j++){
                   8337:       for(i=1; i<=nlstate;i++)
1.268     brouard  8338:        fprintf(ficresfb," b%d%d",i,j);
                   8339:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8340:     }
                   8341:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8342:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8343:       fprintf(ficresfb,"\n");
                   8344:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.269     brouard  8345:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270   ! brouard  8346:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
        !          8347:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8348:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
                   8349:        nhstepm=(int) rint((agec-agelim)*YEARM/stepm);
1.267     brouard  8350:        nhstepm = nhstepm/hstepm;
                   8351:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8352:        oldm=oldms;savm=savms;
1.268     brouard  8353:        /* computes hbxij at age agec over 1 to nhstepm */
1.267     brouard  8354:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8355:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8356:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8357:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8358:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8359:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8360:            break;
                   8361:          }
                   8362:        }
                   8363:        fprintf(ficresfb,"\n");
                   8364:        for(j=1;j<=cptcoveff;j++)
                   8365:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8366:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8367:        for(i=1; i<=nlstate+ndeath;i++) {
                   8368:          ppij=0.;ppi=0.;
                   8369:          for(j=1; j<=nlstate;j++) {
                   8370:            /* if (mobilav==1) */
1.269     brouard  8371:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8372:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8373:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8374:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8375:              /* else { */
                   8376:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8377:              /* } */
1.268     brouard  8378:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8379:          } /* end j */
                   8380:          if(ppi <0.99){
                   8381:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8382:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8383:          }
                   8384:          fprintf(ficresfb," %.3f", ppij);
                   8385:        }/* end j */
1.267     brouard  8386:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8387:       } /* end agec */
                   8388:     } /* end yearp */
                   8389:   } /* end k */
1.217     brouard  8390:   
1.267     brouard  8391:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8392:   
1.267     brouard  8393:   fclose(ficresfb);
                   8394:   printf("End of Computing Back forecasting \n");
                   8395:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8396:        
1.267     brouard  8397: }
1.217     brouard  8398: 
1.269     brouard  8399: /* Variance of prevalence limit: varprlim */
                   8400:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8401:     /*------- Variance of period (stable) prevalence------*/   
                   8402:  
                   8403:    char fileresvpl[FILENAMELENGTH];  
                   8404:    FILE *ficresvpl;
                   8405:    double **oldm, **savm;
                   8406:    double **varpl; /* Variances of prevalence limits by age */   
                   8407:    int i1, k, nres, j ;
                   8408:    
                   8409:     strcpy(fileresvpl,"VPL_");
                   8410:     strcat(fileresvpl,fileresu);
                   8411:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8412:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8413:       exit(0);
                   8414:     }
                   8415:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8416:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8417:     
                   8418:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8419:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8420:     
                   8421:     i1=pow(2,cptcoveff);
                   8422:     if (cptcovn < 1){i1=1;}
                   8423: 
                   8424:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8425:     for(k=1; k<=i1;k++){
                   8426:       if(i1 != 1 && TKresult[nres]!= k)
                   8427:        continue;
                   8428:       fprintf(ficresvpl,"\n#****** ");
                   8429:       printf("\n#****** ");
                   8430:       fprintf(ficlog,"\n#****** ");
                   8431:       for(j=1;j<=cptcoveff;j++) {
                   8432:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8433:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8434:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8435:       }
                   8436:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8437:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8438:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8439:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8440:       }        
                   8441:       fprintf(ficresvpl,"******\n");
                   8442:       printf("******\n");
                   8443:       fprintf(ficlog,"******\n");
                   8444:       
                   8445:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8446:       oldm=oldms;savm=savms;
                   8447:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8448:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8449:       /*}*/
                   8450:     }
                   8451:     
                   8452:     fclose(ficresvpl);
                   8453:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8454:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8455: 
                   8456:  }
                   8457: /* Variance of back prevalence: varbprlim */
                   8458:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8459:       /*------- Variance of back (stable) prevalence------*/
                   8460: 
                   8461:    char fileresvbl[FILENAMELENGTH];  
                   8462:    FILE  *ficresvbl;
                   8463: 
                   8464:    double **oldm, **savm;
                   8465:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8466:    int i1, k, nres, j ;
                   8467: 
                   8468:    strcpy(fileresvbl,"VBL_");
                   8469:    strcat(fileresvbl,fileresu);
                   8470:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8471:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8472:      exit(0);
                   8473:    }
                   8474:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8475:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8476:    
                   8477:    
                   8478:    i1=pow(2,cptcoveff);
                   8479:    if (cptcovn < 1){i1=1;}
                   8480:    
                   8481:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8482:      for(k=1; k<=i1;k++){
                   8483:        if(i1 != 1 && TKresult[nres]!= k)
                   8484:         continue;
                   8485:        fprintf(ficresvbl,"\n#****** ");
                   8486:        printf("\n#****** ");
                   8487:        fprintf(ficlog,"\n#****** ");
                   8488:        for(j=1;j<=cptcoveff;j++) {
                   8489:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8490:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8491:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8492:        }
                   8493:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8494:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8495:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8496:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8497:        }
                   8498:        fprintf(ficresvbl,"******\n");
                   8499:        printf("******\n");
                   8500:        fprintf(ficlog,"******\n");
                   8501:        
                   8502:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8503:        oldm=oldms;savm=savms;
                   8504:        
                   8505:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8506:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8507:        /*}*/
                   8508:      }
                   8509:    
                   8510:    fclose(ficresvbl);
                   8511:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8512:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8513: 
                   8514:  } /* End of varbprlim */
                   8515: 
1.126     brouard  8516: /************** Forecasting *****not tested NB*************/
1.227     brouard  8517: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8518:   
1.227     brouard  8519: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8520: /*   int *popage; */
                   8521: /*   double calagedatem, agelim, kk1, kk2; */
                   8522: /*   double *popeffectif,*popcount; */
                   8523: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8524: /*   /\* double ***mobaverage; *\/ */
                   8525: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8526: 
1.227     brouard  8527: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8528: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8529: /*   agelim=AGESUP; */
                   8530: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8531:   
1.227     brouard  8532: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8533:   
                   8534:   
1.227     brouard  8535: /*   strcpy(filerespop,"POP_");  */
                   8536: /*   strcat(filerespop,fileresu); */
                   8537: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8538: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8539: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8540: /*   } */
                   8541: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8542: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8543: 
1.227     brouard  8544: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8545: 
1.227     brouard  8546: /*   /\* if (mobilav!=0) { *\/ */
                   8547: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8548: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8549: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8550: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8551: /*   /\*   } *\/ */
                   8552: /*   /\* } *\/ */
1.126     brouard  8553: 
1.227     brouard  8554: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8555: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8556:   
1.227     brouard  8557: /*   agelim=AGESUP; */
1.126     brouard  8558:   
1.227     brouard  8559: /*   hstepm=1; */
                   8560: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8561:        
1.227     brouard  8562: /*   if (popforecast==1) { */
                   8563: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8564: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8565: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8566: /*     }  */
                   8567: /*     popage=ivector(0,AGESUP); */
                   8568: /*     popeffectif=vector(0,AGESUP); */
                   8569: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8570:     
1.227     brouard  8571: /*     i=1;    */
                   8572: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8573:     
1.227     brouard  8574: /*     imx=i; */
                   8575: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8576: /*   } */
1.218     brouard  8577:   
1.227     brouard  8578: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8579: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8580: /*       k=k+1; */
                   8581: /*       fprintf(ficrespop,"\n#******"); */
                   8582: /*       for(j=1;j<=cptcoveff;j++) { */
                   8583: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8584: /*       } */
                   8585: /*       fprintf(ficrespop,"******\n"); */
                   8586: /*       fprintf(ficrespop,"# Age"); */
                   8587: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8588: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8589:       
1.227     brouard  8590: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8591: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8592:        
1.227     brouard  8593: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8594: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8595: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8596:          
1.227     brouard  8597: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8598: /*       oldm=oldms;savm=savms; */
                   8599: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8600:          
1.227     brouard  8601: /*       for (h=0; h<=nhstepm; h++){ */
                   8602: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8603: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8604: /*         }  */
                   8605: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8606: /*           kk1=0.;kk2=0; */
                   8607: /*           for(i=1; i<=nlstate;i++) {               */
                   8608: /*             if (mobilav==1)  */
                   8609: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8610: /*             else { */
                   8611: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8612: /*             } */
                   8613: /*           } */
                   8614: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8615: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8616: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8617: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8618: /*           } */
                   8619: /*         } */
                   8620: /*         for(i=1; i<=nlstate;i++){ */
                   8621: /*           kk1=0.; */
                   8622: /*           for(j=1; j<=nlstate;j++){ */
                   8623: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8624: /*           } */
                   8625: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8626: /*         } */
1.218     brouard  8627:            
1.227     brouard  8628: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8629: /*           for(j=1; j<=nlstate;j++)  */
                   8630: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8631: /*       } */
                   8632: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8633: /*     } */
                   8634: /*       } */
1.218     brouard  8635:       
1.227     brouard  8636: /*       /\******\/ */
1.218     brouard  8637:       
1.227     brouard  8638: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8639: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8640: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8641: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8642: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8643:          
1.227     brouard  8644: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8645: /*       oldm=oldms;savm=savms; */
                   8646: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8647: /*       for (h=0; h<=nhstepm; h++){ */
                   8648: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8649: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8650: /*         }  */
                   8651: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8652: /*           kk1=0.;kk2=0; */
                   8653: /*           for(i=1; i<=nlstate;i++) {               */
                   8654: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8655: /*           } */
                   8656: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8657: /*         } */
                   8658: /*       } */
                   8659: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8660: /*     } */
                   8661: /*       } */
                   8662: /*     }  */
                   8663: /*   } */
1.218     brouard  8664:   
1.227     brouard  8665: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8666:   
1.227     brouard  8667: /*   if (popforecast==1) { */
                   8668: /*     free_ivector(popage,0,AGESUP); */
                   8669: /*     free_vector(popeffectif,0,AGESUP); */
                   8670: /*     free_vector(popcount,0,AGESUP); */
                   8671: /*   } */
                   8672: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8673: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8674: /*   fclose(ficrespop); */
                   8675: /* } /\* End of popforecast *\/ */
1.218     brouard  8676:  
1.126     brouard  8677: int fileappend(FILE *fichier, char *optionfich)
                   8678: {
                   8679:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8680:     printf("Problem with file: %s\n", optionfich);
                   8681:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8682:     return (0);
                   8683:   }
                   8684:   fflush(fichier);
                   8685:   return (1);
                   8686: }
                   8687: 
                   8688: 
                   8689: /**************** function prwizard **********************/
                   8690: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8691: {
                   8692: 
                   8693:   /* Wizard to print covariance matrix template */
                   8694: 
1.164     brouard  8695:   char ca[32], cb[32];
                   8696:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8697:   int numlinepar;
                   8698: 
                   8699:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8700:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8701:   for(i=1; i <=nlstate; i++){
                   8702:     jj=0;
                   8703:     for(j=1; j <=nlstate+ndeath; j++){
                   8704:       if(j==i) continue;
                   8705:       jj++;
                   8706:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8707:       printf("%1d%1d",i,j);
                   8708:       fprintf(ficparo,"%1d%1d",i,j);
                   8709:       for(k=1; k<=ncovmodel;k++){
                   8710:        /*        printf(" %lf",param[i][j][k]); */
                   8711:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8712:        printf(" 0.");
                   8713:        fprintf(ficparo," 0.");
                   8714:       }
                   8715:       printf("\n");
                   8716:       fprintf(ficparo,"\n");
                   8717:     }
                   8718:   }
                   8719:   printf("# Scales (for hessian or gradient estimation)\n");
                   8720:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8721:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8722:   for(i=1; i <=nlstate; i++){
                   8723:     jj=0;
                   8724:     for(j=1; j <=nlstate+ndeath; j++){
                   8725:       if(j==i) continue;
                   8726:       jj++;
                   8727:       fprintf(ficparo,"%1d%1d",i,j);
                   8728:       printf("%1d%1d",i,j);
                   8729:       fflush(stdout);
                   8730:       for(k=1; k<=ncovmodel;k++){
                   8731:        /*      printf(" %le",delti3[i][j][k]); */
                   8732:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8733:        printf(" 0.");
                   8734:        fprintf(ficparo," 0.");
                   8735:       }
                   8736:       numlinepar++;
                   8737:       printf("\n");
                   8738:       fprintf(ficparo,"\n");
                   8739:     }
                   8740:   }
                   8741:   printf("# Covariance matrix\n");
                   8742: /* # 121 Var(a12)\n\ */
                   8743: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8744: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8745: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8746: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8747: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8748: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8749: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8750:   fflush(stdout);
                   8751:   fprintf(ficparo,"# Covariance matrix\n");
                   8752:   /* # 121 Var(a12)\n\ */
                   8753:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8754:   /* #   ...\n\ */
                   8755:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8756:   
                   8757:   for(itimes=1;itimes<=2;itimes++){
                   8758:     jj=0;
                   8759:     for(i=1; i <=nlstate; i++){
                   8760:       for(j=1; j <=nlstate+ndeath; j++){
                   8761:        if(j==i) continue;
                   8762:        for(k=1; k<=ncovmodel;k++){
                   8763:          jj++;
                   8764:          ca[0]= k+'a'-1;ca[1]='\0';
                   8765:          if(itimes==1){
                   8766:            printf("#%1d%1d%d",i,j,k);
                   8767:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8768:          }else{
                   8769:            printf("%1d%1d%d",i,j,k);
                   8770:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8771:            /*  printf(" %.5le",matcov[i][j]); */
                   8772:          }
                   8773:          ll=0;
                   8774:          for(li=1;li <=nlstate; li++){
                   8775:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8776:              if(lj==li) continue;
                   8777:              for(lk=1;lk<=ncovmodel;lk++){
                   8778:                ll++;
                   8779:                if(ll<=jj){
                   8780:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8781:                  if(ll<jj){
                   8782:                    if(itimes==1){
                   8783:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8784:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8785:                    }else{
                   8786:                      printf(" 0.");
                   8787:                      fprintf(ficparo," 0.");
                   8788:                    }
                   8789:                  }else{
                   8790:                    if(itimes==1){
                   8791:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8792:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8793:                    }else{
                   8794:                      printf(" 0.");
                   8795:                      fprintf(ficparo," 0.");
                   8796:                    }
                   8797:                  }
                   8798:                }
                   8799:              } /* end lk */
                   8800:            } /* end lj */
                   8801:          } /* end li */
                   8802:          printf("\n");
                   8803:          fprintf(ficparo,"\n");
                   8804:          numlinepar++;
                   8805:        } /* end k*/
                   8806:       } /*end j */
                   8807:     } /* end i */
                   8808:   } /* end itimes */
                   8809: 
                   8810: } /* end of prwizard */
                   8811: /******************* Gompertz Likelihood ******************************/
                   8812: double gompertz(double x[])
                   8813: { 
                   8814:   double A,B,L=0.0,sump=0.,num=0.;
                   8815:   int i,n=0; /* n is the size of the sample */
                   8816: 
1.220     brouard  8817:   for (i=1;i<=imx ; i++) {
1.126     brouard  8818:     sump=sump+weight[i];
                   8819:     /*    sump=sump+1;*/
                   8820:     num=num+1;
                   8821:   }
                   8822:  
                   8823:  
                   8824:   /* for (i=0; i<=imx; i++) 
                   8825:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8826: 
                   8827:   for (i=1;i<=imx ; i++)
                   8828:     {
                   8829:       if (cens[i] == 1 && wav[i]>1)
                   8830:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8831:       
                   8832:       if (cens[i] == 0 && wav[i]>1)
                   8833:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8834:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8835:       
                   8836:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8837:       if (wav[i] > 1 ) { /* ??? */
                   8838:        L=L+A*weight[i];
                   8839:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8840:       }
                   8841:     }
                   8842: 
                   8843:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8844:  
                   8845:   return -2*L*num/sump;
                   8846: }
                   8847: 
1.136     brouard  8848: #ifdef GSL
                   8849: /******************* Gompertz_f Likelihood ******************************/
                   8850: double gompertz_f(const gsl_vector *v, void *params)
                   8851: { 
                   8852:   double A,B,LL=0.0,sump=0.,num=0.;
                   8853:   double *x= (double *) v->data;
                   8854:   int i,n=0; /* n is the size of the sample */
                   8855: 
                   8856:   for (i=0;i<=imx-1 ; i++) {
                   8857:     sump=sump+weight[i];
                   8858:     /*    sump=sump+1;*/
                   8859:     num=num+1;
                   8860:   }
                   8861:  
                   8862:  
                   8863:   /* for (i=0; i<=imx; i++) 
                   8864:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8865:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8866:   for (i=1;i<=imx ; i++)
                   8867:     {
                   8868:       if (cens[i] == 1 && wav[i]>1)
                   8869:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8870:       
                   8871:       if (cens[i] == 0 && wav[i]>1)
                   8872:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8873:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8874:       
                   8875:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8876:       if (wav[i] > 1 ) { /* ??? */
                   8877:        LL=LL+A*weight[i];
                   8878:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8879:       }
                   8880:     }
                   8881: 
                   8882:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8883:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8884:  
                   8885:   return -2*LL*num/sump;
                   8886: }
                   8887: #endif
                   8888: 
1.126     brouard  8889: /******************* Printing html file ***********/
1.201     brouard  8890: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8891:                  int lastpass, int stepm, int weightopt, char model[],\
                   8892:                  int imx,  double p[],double **matcov,double agemortsup){
                   8893:   int i,k;
                   8894: 
                   8895:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8896:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8897:   for (i=1;i<=2;i++) 
                   8898:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8899:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8900:   fprintf(fichtm,"</ul>");
                   8901: 
                   8902: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8903: 
                   8904:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8905: 
                   8906:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8907:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8908: 
                   8909:  
                   8910:   fflush(fichtm);
                   8911: }
                   8912: 
                   8913: /******************* Gnuplot file **************/
1.201     brouard  8914: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8915: 
                   8916:   char dirfileres[132],optfileres[132];
1.164     brouard  8917: 
1.126     brouard  8918:   int ng;
                   8919: 
                   8920: 
                   8921:   /*#ifdef windows */
                   8922:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8923:     /*#endif */
                   8924: 
                   8925: 
                   8926:   strcpy(dirfileres,optionfilefiname);
                   8927:   strcpy(optfileres,"vpl");
1.199     brouard  8928:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8929:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8930:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8931:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8932:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8933: 
                   8934: } 
                   8935: 
1.136     brouard  8936: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8937: {
1.126     brouard  8938: 
1.136     brouard  8939:   /*-------- data file ----------*/
                   8940:   FILE *fic;
                   8941:   char dummy[]="                         ";
1.240     brouard  8942:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8943:   int lstra;
1.136     brouard  8944:   int linei, month, year,iout;
                   8945:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8946:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8947:   char *stratrunc;
1.223     brouard  8948: 
1.240     brouard  8949:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8950:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8951: 
1.240     brouard  8952:   for(v=1; v <=ncovcol;v++){
                   8953:     DummyV[v]=0;
                   8954:     FixedV[v]=0;
                   8955:   }
                   8956:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8957:     DummyV[v]=1;
                   8958:     FixedV[v]=0;
                   8959:   }
                   8960:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8961:     DummyV[v]=0;
                   8962:     FixedV[v]=1;
                   8963:   }
                   8964:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8965:     DummyV[v]=1;
                   8966:     FixedV[v]=1;
                   8967:   }
                   8968:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8969:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8970:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8971:   }
1.126     brouard  8972: 
1.136     brouard  8973:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8974:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8975:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8976:   }
1.126     brouard  8977: 
1.136     brouard  8978:   i=1;
                   8979:   linei=0;
                   8980:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8981:     linei=linei+1;
                   8982:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8983:       if(line[j] == '\t')
                   8984:        line[j] = ' ';
                   8985:     }
                   8986:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8987:       ;
                   8988:     };
                   8989:     line[j+1]=0;  /* Trims blanks at end of line */
                   8990:     if(line[0]=='#'){
                   8991:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8992:       printf("Comment line\n%s\n",line);
                   8993:       continue;
                   8994:     }
                   8995:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8996:     strcpy(line, linetmp);
1.223     brouard  8997:     
                   8998:     /* Loops on waves */
                   8999:     for (j=maxwav;j>=1;j--){
                   9000:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9001:        cutv(stra, strb, line, ' '); 
                   9002:        if(strb[0]=='.') { /* Missing value */
                   9003:          lval=-1;
                   9004:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9005:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9006:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9007:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9008:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9009:            return 1;
                   9010:          }
                   9011:        }else{
                   9012:          errno=0;
                   9013:          /* what_kind_of_number(strb); */
                   9014:          dval=strtod(strb,&endptr); 
                   9015:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9016:          /* if(strb != endptr && *endptr == '\0') */
                   9017:          /*    dval=dlval; */
                   9018:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9019:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9020:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9021:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9022:            return 1;
                   9023:          }
                   9024:          cotqvar[j][iv][i]=dval; 
                   9025:          cotvar[j][ntv+iv][i]=dval; 
                   9026:        }
                   9027:        strcpy(line,stra);
1.223     brouard  9028:       }/* end loop ntqv */
1.225     brouard  9029:       
1.223     brouard  9030:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9031:        cutv(stra, strb, line, ' '); 
                   9032:        if(strb[0]=='.') { /* Missing value */
                   9033:          lval=-1;
                   9034:        }else{
                   9035:          errno=0;
                   9036:          lval=strtol(strb,&endptr,10); 
                   9037:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9038:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9039:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9040:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9041:            return 1;
                   9042:          }
                   9043:        }
                   9044:        if(lval <-1 || lval >1){
                   9045:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9046:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9047:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9048:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9049:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9050:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9051:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9052:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9053:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9054:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9055:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9056:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9057:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9058:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9059:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9060:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9061:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9062:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9063:          return 1;
                   9064:        }
                   9065:        cotvar[j][iv][i]=(double)(lval);
                   9066:        strcpy(line,stra);
1.223     brouard  9067:       }/* end loop ntv */
1.225     brouard  9068:       
1.223     brouard  9069:       /* Statuses  at wave */
1.137     brouard  9070:       cutv(stra, strb, line, ' '); 
1.223     brouard  9071:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9072:        lval=-1;
1.136     brouard  9073:       }else{
1.238     brouard  9074:        errno=0;
                   9075:        lval=strtol(strb,&endptr,10); 
                   9076:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9077:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9078:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9079:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9080:          return 1;
                   9081:        }
1.136     brouard  9082:       }
1.225     brouard  9083:       
1.136     brouard  9084:       s[j][i]=lval;
1.225     brouard  9085:       
1.223     brouard  9086:       /* Date of Interview */
1.136     brouard  9087:       strcpy(line,stra);
                   9088:       cutv(stra, strb,line,' ');
1.169     brouard  9089:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9090:       }
1.169     brouard  9091:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9092:        month=99;
                   9093:        year=9999;
1.136     brouard  9094:       }else{
1.225     brouard  9095:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9096:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9097:        return 1;
1.136     brouard  9098:       }
                   9099:       anint[j][i]= (double) year; 
                   9100:       mint[j][i]= (double)month; 
                   9101:       strcpy(line,stra);
1.223     brouard  9102:     } /* End loop on waves */
1.225     brouard  9103:     
1.223     brouard  9104:     /* Date of death */
1.136     brouard  9105:     cutv(stra, strb,line,' '); 
1.169     brouard  9106:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9107:     }
1.169     brouard  9108:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9109:       month=99;
                   9110:       year=9999;
                   9111:     }else{
1.141     brouard  9112:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9113:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9114:       return 1;
1.136     brouard  9115:     }
                   9116:     andc[i]=(double) year; 
                   9117:     moisdc[i]=(double) month; 
                   9118:     strcpy(line,stra);
                   9119:     
1.223     brouard  9120:     /* Date of birth */
1.136     brouard  9121:     cutv(stra, strb,line,' '); 
1.169     brouard  9122:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9123:     }
1.169     brouard  9124:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9125:       month=99;
                   9126:       year=9999;
                   9127:     }else{
1.141     brouard  9128:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9129:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9130:       return 1;
1.136     brouard  9131:     }
                   9132:     if (year==9999) {
1.141     brouard  9133:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9134:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9135:       return 1;
                   9136:       
1.136     brouard  9137:     }
                   9138:     annais[i]=(double)(year);
                   9139:     moisnais[i]=(double)(month); 
                   9140:     strcpy(line,stra);
1.225     brouard  9141:     
1.223     brouard  9142:     /* Sample weight */
1.136     brouard  9143:     cutv(stra, strb,line,' '); 
                   9144:     errno=0;
                   9145:     dval=strtod(strb,&endptr); 
                   9146:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9147:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9148:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9149:       fflush(ficlog);
                   9150:       return 1;
                   9151:     }
                   9152:     weight[i]=dval; 
                   9153:     strcpy(line,stra);
1.225     brouard  9154:     
1.223     brouard  9155:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9156:       cutv(stra, strb, line, ' '); 
                   9157:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9158:        lval=-1;
1.223     brouard  9159:       }else{
1.225     brouard  9160:        errno=0;
                   9161:        /* what_kind_of_number(strb); */
                   9162:        dval=strtod(strb,&endptr);
                   9163:        /* if(strb != endptr && *endptr == '\0') */
                   9164:        /*   dval=dlval; */
                   9165:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9166:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9167:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9168:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9169:          return 1;
                   9170:        }
                   9171:        coqvar[iv][i]=dval; 
1.226     brouard  9172:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9173:       }
                   9174:       strcpy(line,stra);
                   9175:     }/* end loop nqv */
1.136     brouard  9176:     
1.223     brouard  9177:     /* Covariate values */
1.136     brouard  9178:     for (j=ncovcol;j>=1;j--){
                   9179:       cutv(stra, strb,line,' '); 
1.223     brouard  9180:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9181:        lval=-1;
1.136     brouard  9182:       }else{
1.225     brouard  9183:        errno=0;
                   9184:        lval=strtol(strb,&endptr,10); 
                   9185:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9186:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9187:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9188:          return 1;
                   9189:        }
1.136     brouard  9190:       }
                   9191:       if(lval <-1 || lval >1){
1.225     brouard  9192:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9193:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9194:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9195:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9196:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9197:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9198:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9199:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9200:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9201:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9202:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9203:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9204:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9205:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9206:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9207:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9208:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9209:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9210:        return 1;
1.136     brouard  9211:       }
                   9212:       covar[j][i]=(double)(lval);
                   9213:       strcpy(line,stra);
                   9214:     }  
                   9215:     lstra=strlen(stra);
1.225     brouard  9216:     
1.136     brouard  9217:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9218:       stratrunc = &(stra[lstra-9]);
                   9219:       num[i]=atol(stratrunc);
                   9220:     }
                   9221:     else
                   9222:       num[i]=atol(stra);
                   9223:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9224:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9225:     
                   9226:     i=i+1;
                   9227:   } /* End loop reading  data */
1.225     brouard  9228:   
1.136     brouard  9229:   *imax=i-1; /* Number of individuals */
                   9230:   fclose(fic);
1.225     brouard  9231:   
1.136     brouard  9232:   return (0);
1.164     brouard  9233:   /* endread: */
1.225     brouard  9234:   printf("Exiting readdata: ");
                   9235:   fclose(fic);
                   9236:   return (1);
1.223     brouard  9237: }
1.126     brouard  9238: 
1.234     brouard  9239: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9240:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9241:   while (*p2 == ' ')
1.234     brouard  9242:     p2++; 
                   9243:   /* while ((*p1++ = *p2++) !=0) */
                   9244:   /*   ; */
                   9245:   /* do */
                   9246:   /*   while (*p2 == ' ') */
                   9247:   /*     p2++; */
                   9248:   /* while (*p1++ == *p2++); */
                   9249:   *stri=p2; 
1.145     brouard  9250: }
                   9251: 
1.235     brouard  9252: int decoderesult ( char resultline[], int nres)
1.230     brouard  9253: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9254: {
1.235     brouard  9255:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9256:   char resultsav[MAXLINE];
1.234     brouard  9257:   int resultmodel[MAXLINE];
                   9258:   int modelresult[MAXLINE];
1.230     brouard  9259:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9260: 
1.234     brouard  9261:   removefirstspace(&resultline);
1.233     brouard  9262:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9263: 
                   9264:   if (strstr(resultline,"v") !=0){
                   9265:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9266:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9267:     return 1;
                   9268:   }
                   9269:   trimbb(resultsav, resultline);
                   9270:   if (strlen(resultsav) >1){
                   9271:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9272:   }
1.253     brouard  9273:   if(j == 0){ /* Resultline but no = */
                   9274:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9275:     return (0);
                   9276:   }
                   9277:     
1.234     brouard  9278:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9279:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9280:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9281:   }
                   9282:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9283:     if(nbocc(resultsav,'=') >1){
                   9284:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9285:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9286:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9287:     }else
                   9288:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9289:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9290:     
1.230     brouard  9291:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9292:     Tvarsel[k]=atoi(strc);
                   9293:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9294:     /* cptcovsel++;     */
                   9295:     if (nbocc(stra,'=') >0)
                   9296:       strcpy(resultsav,stra); /* and analyzes it */
                   9297:   }
1.235     brouard  9298:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9299:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9300:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9301:       match=0;
1.236     brouard  9302:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9303:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9304:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9305:          match=1;
                   9306:          break;
                   9307:        }
                   9308:       }
                   9309:       if(match == 0){
                   9310:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9311:       }
                   9312:     }
                   9313:   }
1.235     brouard  9314:   /* Checking for missing or useless values in comparison of current model needs */
                   9315:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9316:     match=0;
1.235     brouard  9317:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9318:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9319:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9320:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9321:          ++match;
                   9322:        }
                   9323:       }
                   9324:     }
                   9325:     if(match == 0){
                   9326:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9327:     }else if(match > 1){
                   9328:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9329:     }
                   9330:   }
1.235     brouard  9331:       
1.234     brouard  9332:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9333:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9334:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9335:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9336:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9337:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9338:   /*    1 0 0 0 */
                   9339:   /*    2 1 0 0 */
                   9340:   /*    3 0 1 0 */ 
                   9341:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9342:   /*    5 0 0 1 */
                   9343:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9344:   /*    7 0 1 1 */
                   9345:   /*    8 1 1 1 */
1.237     brouard  9346:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9347:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9348:   /* V5*age V5 known which value for nres?  */
                   9349:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9350:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9351:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9352:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9353:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9354:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9355:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9356:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9357:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9358:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9359:       k4++;;
                   9360:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9361:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9362:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9363:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9364:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9365:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9366:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9367:       k4q++;;
                   9368:     }
                   9369:   }
1.234     brouard  9370:   
1.235     brouard  9371:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9372:   return (0);
                   9373: }
1.235     brouard  9374: 
1.230     brouard  9375: int decodemodel( char model[], int lastobs)
                   9376:  /**< This routine decodes the model and returns:
1.224     brouard  9377:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9378:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9379:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9380:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9381:        * - cptcovage number of covariates with age*products =2
                   9382:        * - cptcovs number of simple covariates
                   9383:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9384:        *     which is a new column after the 9 (ncovcol) variables. 
                   9385:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9386:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9387:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9388:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9389:        */
1.136     brouard  9390: {
1.238     brouard  9391:   int i, j, k, ks, v;
1.227     brouard  9392:   int  j1, k1, k2, k3, k4;
1.136     brouard  9393:   char modelsav[80];
1.145     brouard  9394:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9395:   char *strpt;
1.136     brouard  9396: 
1.145     brouard  9397:   /*removespace(model);*/
1.136     brouard  9398:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9399:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9400:     if (strstr(model,"AGE") !=0){
1.192     brouard  9401:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9402:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9403:       return 1;
                   9404:     }
1.141     brouard  9405:     if (strstr(model,"v") !=0){
                   9406:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9407:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9408:       return 1;
                   9409:     }
1.187     brouard  9410:     strcpy(modelsav,model); 
                   9411:     if ((strpt=strstr(model,"age*age")) !=0){
                   9412:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9413:       if(strpt != model){
1.234     brouard  9414:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9415:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9416:  corresponding column of parameters.\n",model);
1.234     brouard  9417:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9418:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9419:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9420:        return 1;
1.225     brouard  9421:       }
1.187     brouard  9422:       nagesqr=1;
                   9423:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9424:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9425:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9426:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9427:       else 
1.234     brouard  9428:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9429:     }else
                   9430:       nagesqr=0;
                   9431:     if (strlen(modelsav) >1){
                   9432:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9433:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9434:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9435:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9436:                     * cst, age and age*age 
                   9437:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9438:       /* including age products which are counted in cptcovage.
                   9439:        * but the covariates which are products must be treated 
                   9440:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9441:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9442:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9443:       
                   9444:       
1.187     brouard  9445:       /*   Design
                   9446:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9447:        *  <          ncovcol=8                >
                   9448:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9449:        *   k=  1    2      3       4     5       6      7        8
                   9450:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9451:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9452:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9453:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9454:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9455:        *  Tage[++cptcovage]=k
                   9456:        *       if products, new covar are created after ncovcol with k1
                   9457:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9458:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9459:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9460:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9461:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9462:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9463:        *  <          ncovcol=8                >
                   9464:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9465:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9466:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9467:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9468:        * p Tprod[1]@2={                         6, 5}
                   9469:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9470:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9471:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9472:        *How to reorganize?
                   9473:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9474:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9475:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9476:        * Struct []
                   9477:        */
1.225     brouard  9478:       
1.187     brouard  9479:       /* This loop fills the array Tvar from the string 'model'.*/
                   9480:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9481:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9482:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9483:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9484:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9485:       /*       k=1 Tvar[1]=2 (from V2) */
                   9486:       /*       k=5 Tvar[5] */
                   9487:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9488:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9489:       /*       } */
1.198     brouard  9490:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9491:       /*
                   9492:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9493:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9494:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9495:       }
1.187     brouard  9496:       cptcovage=0;
                   9497:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9498:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9499:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9500:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9501:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9502:        /*scanf("%d",i);*/
                   9503:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9504:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9505:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9506:            /* covar is not filled and then is empty */
                   9507:            cptcovprod--;
                   9508:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9509:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9510:            Typevar[k]=1;  /* 1 for age product */
                   9511:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9512:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9513:            /*printf("stre=%s ", stre);*/
                   9514:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9515:            cptcovprod--;
                   9516:            cutl(stre,strb,strc,'V');
                   9517:            Tvar[k]=atoi(stre);
                   9518:            Typevar[k]=1;  /* 1 for age product */
                   9519:            cptcovage++;
                   9520:            Tage[cptcovage]=k;
                   9521:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9522:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9523:            cptcovn++;
                   9524:            cptcovprodnoage++;k1++;
                   9525:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9526:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9527:                                                because this model-covariate is a construction we invent a new column
                   9528:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9529:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9530:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9531:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9532:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9533:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9534:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9535:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9536:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9537:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9538:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9539:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9540:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9541:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9542:            for (i=1; i<=lastobs;i++){
                   9543:              /* Computes the new covariate which is a product of
                   9544:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9545:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9546:            }
                   9547:          } /* End age is not in the model */
                   9548:        } /* End if model includes a product */
                   9549:        else { /* no more sum */
                   9550:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9551:          /*  scanf("%d",i);*/
                   9552:          cutl(strd,strc,strb,'V');
                   9553:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9554:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9555:          Tvar[k]=atoi(strd);
                   9556:          Typevar[k]=0;  /* 0 for simple covariates */
                   9557:        }
                   9558:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9559:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9560:                                  scanf("%d",i);*/
1.187     brouard  9561:       } /* end of loop + on total covariates */
                   9562:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9563:   } /* end if strlen(model == 0) */
1.136     brouard  9564:   
                   9565:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9566:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9567:   
1.136     brouard  9568:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9569:      printf("cptcovprod=%d ", cptcovprod);
                   9570:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9571:      scanf("%d ",i);*/
                   9572: 
                   9573: 
1.230     brouard  9574: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9575:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9576: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9577:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9578:    k =           1    2   3     4       5       6      7      8        9
                   9579:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9580:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9581:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9582:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9583:          Tmodelind[combination of covar]=k;
1.225     brouard  9584: */  
                   9585: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9586:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9587:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9588:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9589:   printf("Model=%s\n\
                   9590: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9591: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9592: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9593:   fprintf(ficlog,"Model=%s\n\
                   9594: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9595: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9596: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9597:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9598:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9599:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9600:       Fixed[k]= 0;
                   9601:       Dummy[k]= 0;
1.225     brouard  9602:       ncoveff++;
1.232     brouard  9603:       ncovf++;
1.234     brouard  9604:       nsd++;
                   9605:       modell[k].maintype= FTYPE;
                   9606:       TvarsD[nsd]=Tvar[k];
                   9607:       TvarsDind[nsd]=k;
                   9608:       TvarF[ncovf]=Tvar[k];
                   9609:       TvarFind[ncovf]=k;
                   9610:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9611:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9612:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9613:       Fixed[k]= 0;
                   9614:       Dummy[k]= 0;
                   9615:       ncoveff++;
                   9616:       ncovf++;
                   9617:       modell[k].maintype= FTYPE;
                   9618:       TvarF[ncovf]=Tvar[k];
                   9619:       TvarFind[ncovf]=k;
1.230     brouard  9620:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9621:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9622:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9623:       Fixed[k]= 0;
                   9624:       Dummy[k]= 1;
1.230     brouard  9625:       nqfveff++;
1.234     brouard  9626:       modell[k].maintype= FTYPE;
                   9627:       modell[k].subtype= FQ;
                   9628:       nsq++;
                   9629:       TvarsQ[nsq]=Tvar[k];
                   9630:       TvarsQind[nsq]=k;
1.232     brouard  9631:       ncovf++;
1.234     brouard  9632:       TvarF[ncovf]=Tvar[k];
                   9633:       TvarFind[ncovf]=k;
1.231     brouard  9634:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9635:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9636:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9637:       Fixed[k]= 1;
                   9638:       Dummy[k]= 0;
1.225     brouard  9639:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9640:       modell[k].maintype= VTYPE;
                   9641:       modell[k].subtype= VD;
                   9642:       nsd++;
                   9643:       TvarsD[nsd]=Tvar[k];
                   9644:       TvarsDind[nsd]=k;
                   9645:       ncovv++; /* Only simple time varying variables */
                   9646:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9647:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9648:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9649:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9650:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9651:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9652:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9653:       Fixed[k]= 1;
                   9654:       Dummy[k]= 1;
                   9655:       nqtveff++;
                   9656:       modell[k].maintype= VTYPE;
                   9657:       modell[k].subtype= VQ;
                   9658:       ncovv++; /* Only simple time varying variables */
                   9659:       nsq++;
                   9660:       TvarsQ[nsq]=Tvar[k];
                   9661:       TvarsQind[nsq]=k;
                   9662:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9663:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9664:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9665:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9666:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9667:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9668:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9669:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9670:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9671:       ncova++;
                   9672:       TvarA[ncova]=Tvar[k];
                   9673:       TvarAind[ncova]=k;
1.231     brouard  9674:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9675:        Fixed[k]= 2;
                   9676:        Dummy[k]= 2;
                   9677:        modell[k].maintype= ATYPE;
                   9678:        modell[k].subtype= APFD;
                   9679:        /* ncoveff++; */
1.227     brouard  9680:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9681:        Fixed[k]= 2;
                   9682:        Dummy[k]= 3;
                   9683:        modell[k].maintype= ATYPE;
                   9684:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9685:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9686:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9687:        Fixed[k]= 3;
                   9688:        Dummy[k]= 2;
                   9689:        modell[k].maintype= ATYPE;
                   9690:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9691:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9692:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9693:        Fixed[k]= 3;
                   9694:        Dummy[k]= 3;
                   9695:        modell[k].maintype= ATYPE;
                   9696:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9697:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9698:       }
                   9699:     }else if (Typevar[k] == 2) {  /* product without age */
                   9700:       k1=Tposprod[k];
                   9701:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9702:        if(Tvard[k1][2] <=ncovcol){
                   9703:          Fixed[k]= 1;
                   9704:          Dummy[k]= 0;
                   9705:          modell[k].maintype= FTYPE;
                   9706:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9707:          ncovf++; /* Fixed variables without age */
                   9708:          TvarF[ncovf]=Tvar[k];
                   9709:          TvarFind[ncovf]=k;
                   9710:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9711:          Fixed[k]= 0;  /* or 2 ?*/
                   9712:          Dummy[k]= 1;
                   9713:          modell[k].maintype= FTYPE;
                   9714:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9715:          ncovf++; /* Varying variables without age */
                   9716:          TvarF[ncovf]=Tvar[k];
                   9717:          TvarFind[ncovf]=k;
                   9718:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9719:          Fixed[k]= 1;
                   9720:          Dummy[k]= 0;
                   9721:          modell[k].maintype= VTYPE;
                   9722:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9723:          ncovv++; /* Varying variables without age */
                   9724:          TvarV[ncovv]=Tvar[k];
                   9725:          TvarVind[ncovv]=k;
                   9726:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9727:          Fixed[k]= 1;
                   9728:          Dummy[k]= 1;
                   9729:          modell[k].maintype= VTYPE;
                   9730:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9731:          ncovv++; /* Varying variables without age */
                   9732:          TvarV[ncovv]=Tvar[k];
                   9733:          TvarVind[ncovv]=k;
                   9734:        }
1.227     brouard  9735:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9736:        if(Tvard[k1][2] <=ncovcol){
                   9737:          Fixed[k]= 0;  /* or 2 ?*/
                   9738:          Dummy[k]= 1;
                   9739:          modell[k].maintype= FTYPE;
                   9740:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9741:          ncovf++; /* Fixed variables without age */
                   9742:          TvarF[ncovf]=Tvar[k];
                   9743:          TvarFind[ncovf]=k;
                   9744:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9745:          Fixed[k]= 1;
                   9746:          Dummy[k]= 1;
                   9747:          modell[k].maintype= VTYPE;
                   9748:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9749:          ncovv++; /* Varying variables without age */
                   9750:          TvarV[ncovv]=Tvar[k];
                   9751:          TvarVind[ncovv]=k;
                   9752:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9753:          Fixed[k]= 1;
                   9754:          Dummy[k]= 1;
                   9755:          modell[k].maintype= VTYPE;
                   9756:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9757:          ncovv++; /* Varying variables without age */
                   9758:          TvarV[ncovv]=Tvar[k];
                   9759:          TvarVind[ncovv]=k;
                   9760:          ncovv++; /* Varying variables without age */
                   9761:          TvarV[ncovv]=Tvar[k];
                   9762:          TvarVind[ncovv]=k;
                   9763:        }
1.227     brouard  9764:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9765:        if(Tvard[k1][2] <=ncovcol){
                   9766:          Fixed[k]= 1;
                   9767:          Dummy[k]= 1;
                   9768:          modell[k].maintype= VTYPE;
                   9769:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9770:          ncovv++; /* Varying variables without age */
                   9771:          TvarV[ncovv]=Tvar[k];
                   9772:          TvarVind[ncovv]=k;
                   9773:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9774:          Fixed[k]= 1;
                   9775:          Dummy[k]= 1;
                   9776:          modell[k].maintype= VTYPE;
                   9777:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9778:          ncovv++; /* Varying variables without age */
                   9779:          TvarV[ncovv]=Tvar[k];
                   9780:          TvarVind[ncovv]=k;
                   9781:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9782:          Fixed[k]= 1;
                   9783:          Dummy[k]= 0;
                   9784:          modell[k].maintype= VTYPE;
                   9785:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9786:          ncovv++; /* Varying variables without age */
                   9787:          TvarV[ncovv]=Tvar[k];
                   9788:          TvarVind[ncovv]=k;
                   9789:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9790:          Fixed[k]= 1;
                   9791:          Dummy[k]= 1;
                   9792:          modell[k].maintype= VTYPE;
                   9793:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9794:          ncovv++; /* Varying variables without age */
                   9795:          TvarV[ncovv]=Tvar[k];
                   9796:          TvarVind[ncovv]=k;
                   9797:        }
1.227     brouard  9798:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9799:        if(Tvard[k1][2] <=ncovcol){
                   9800:          Fixed[k]= 1;
                   9801:          Dummy[k]= 1;
                   9802:          modell[k].maintype= VTYPE;
                   9803:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9804:          ncovv++; /* Varying variables without age */
                   9805:          TvarV[ncovv]=Tvar[k];
                   9806:          TvarVind[ncovv]=k;
                   9807:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9808:          Fixed[k]= 1;
                   9809:          Dummy[k]= 1;
                   9810:          modell[k].maintype= VTYPE;
                   9811:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9812:          ncovv++; /* Varying variables without age */
                   9813:          TvarV[ncovv]=Tvar[k];
                   9814:          TvarVind[ncovv]=k;
                   9815:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9816:          Fixed[k]= 1;
                   9817:          Dummy[k]= 1;
                   9818:          modell[k].maintype= VTYPE;
                   9819:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9820:          ncovv++; /* Varying variables without age */
                   9821:          TvarV[ncovv]=Tvar[k];
                   9822:          TvarVind[ncovv]=k;
                   9823:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9824:          Fixed[k]= 1;
                   9825:          Dummy[k]= 1;
                   9826:          modell[k].maintype= VTYPE;
                   9827:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9828:          ncovv++; /* Varying variables without age */
                   9829:          TvarV[ncovv]=Tvar[k];
                   9830:          TvarVind[ncovv]=k;
                   9831:        }
1.227     brouard  9832:       }else{
1.240     brouard  9833:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9834:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9835:       } /*end k1*/
1.225     brouard  9836:     }else{
1.226     brouard  9837:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9838:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9839:     }
1.227     brouard  9840:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9841:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9842:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9843:   }
                   9844:   /* Searching for doublons in the model */
                   9845:   for(k1=1; k1<= cptcovt;k1++){
                   9846:     for(k2=1; k2 <k1;k2++){
                   9847:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9848:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9849:          if(Tvar[k1]==Tvar[k2]){
                   9850:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9851:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9852:            return(1);
                   9853:          }
                   9854:        }else if (Typevar[k1] ==2){
                   9855:          k3=Tposprod[k1];
                   9856:          k4=Tposprod[k2];
                   9857:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9858:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9859:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9860:            return(1);
                   9861:          }
                   9862:        }
1.227     brouard  9863:       }
                   9864:     }
1.225     brouard  9865:   }
                   9866:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9867:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9868:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9869:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9870:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9871:   /*endread:*/
1.225     brouard  9872:   printf("Exiting decodemodel: ");
                   9873:   return (1);
1.136     brouard  9874: }
                   9875: 
1.169     brouard  9876: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9877: {/* Check ages at death */
1.136     brouard  9878:   int i, m;
1.218     brouard  9879:   int firstone=0;
                   9880:   
1.136     brouard  9881:   for (i=1; i<=imx; i++) {
                   9882:     for(m=2; (m<= maxwav); m++) {
                   9883:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9884:        anint[m][i]=9999;
1.216     brouard  9885:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9886:          s[m][i]=-1;
1.136     brouard  9887:       }
                   9888:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9889:        *nberr = *nberr + 1;
1.218     brouard  9890:        if(firstone == 0){
                   9891:          firstone=1;
1.260     brouard  9892:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9893:        }
1.262     brouard  9894:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9895:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9896:       }
                   9897:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9898:        (*nberr)++;
1.259     brouard  9899:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9900:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9901:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9902:       }
                   9903:     }
                   9904:   }
                   9905: 
                   9906:   for (i=1; i<=imx; i++)  {
                   9907:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9908:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9909:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9910:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9911:          if(agedc[i]>0){
                   9912:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9913:              agev[m][i]=agedc[i];
1.214     brouard  9914:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9915:            }else {
1.136     brouard  9916:              if ((int)andc[i]!=9999){
                   9917:                nbwarn++;
                   9918:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9919:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9920:                agev[m][i]=-1;
                   9921:              }
                   9922:            }
1.169     brouard  9923:          } /* agedc > 0 */
1.214     brouard  9924:        } /* end if */
1.136     brouard  9925:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9926:                                 years but with the precision of a month */
                   9927:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9928:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9929:            agev[m][i]=1;
                   9930:          else if(agev[m][i] < *agemin){ 
                   9931:            *agemin=agev[m][i];
                   9932:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9933:          }
                   9934:          else if(agev[m][i] >*agemax){
                   9935:            *agemax=agev[m][i];
1.156     brouard  9936:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9937:          }
                   9938:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9939:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9940:        } /* en if 9*/
1.136     brouard  9941:        else { /* =9 */
1.214     brouard  9942:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9943:          agev[m][i]=1;
                   9944:          s[m][i]=-1;
                   9945:        }
                   9946:       }
1.214     brouard  9947:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9948:        agev[m][i]=1;
1.214     brouard  9949:       else{
                   9950:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9951:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9952:        agev[m][i]=0;
                   9953:       }
                   9954:     } /* End for lastpass */
                   9955:   }
1.136     brouard  9956:     
                   9957:   for (i=1; i<=imx; i++)  {
                   9958:     for(m=firstpass; (m<=lastpass); m++){
                   9959:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9960:        (*nberr)++;
1.136     brouard  9961:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9962:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9963:        return 1;
                   9964:       }
                   9965:     }
                   9966:   }
                   9967: 
                   9968:   /*for (i=1; i<=imx; i++){
                   9969:   for (m=firstpass; (m<lastpass); m++){
                   9970:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9971: }
                   9972: 
                   9973: }*/
                   9974: 
                   9975: 
1.139     brouard  9976:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9977:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9978: 
                   9979:   return (0);
1.164     brouard  9980:  /* endread:*/
1.136     brouard  9981:     printf("Exiting calandcheckages: ");
                   9982:     return (1);
                   9983: }
                   9984: 
1.172     brouard  9985: #if defined(_MSC_VER)
                   9986: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9987: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9988: //#include "stdafx.h"
                   9989: //#include <stdio.h>
                   9990: //#include <tchar.h>
                   9991: //#include <windows.h>
                   9992: //#include <iostream>
                   9993: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9994: 
                   9995: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9996: 
                   9997: BOOL IsWow64()
                   9998: {
                   9999:        BOOL bIsWow64 = FALSE;
                   10000: 
                   10001:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10002:        //  (HANDLE, PBOOL);
                   10003: 
                   10004:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10005: 
                   10006:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10007:        const char funcName[] = "IsWow64Process";
                   10008:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10009:                GetProcAddress(module, funcName);
                   10010: 
                   10011:        if (NULL != fnIsWow64Process)
                   10012:        {
                   10013:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10014:                        &bIsWow64))
                   10015:                        //throw std::exception("Unknown error");
                   10016:                        printf("Unknown error\n");
                   10017:        }
                   10018:        return bIsWow64 != FALSE;
                   10019: }
                   10020: #endif
1.177     brouard  10021: 
1.191     brouard  10022: void syscompilerinfo(int logged)
1.167     brouard  10023:  {
                   10024:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10025:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10026:    /* /GS /W3 /Gy
                   10027:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10028:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10029:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10030:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10031:    */ 
                   10032:    /* 64 bits */
1.185     brouard  10033:    /*
                   10034:      /GS /W3 /Gy
                   10035:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10036:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10037:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10038:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10039:    /* Optimization are useless and O3 is slower than O2 */
                   10040:    /*
                   10041:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10042:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10043:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10044:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10045:    */
1.186     brouard  10046:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10047:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10048:       /PDB:"visual studio
                   10049:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10050:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10051:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10052:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10053:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10054:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10055:       uiAccess='false'"
                   10056:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10057:       /NOLOGO /TLBID:1
                   10058:    */
1.177     brouard  10059: #if defined __INTEL_COMPILER
1.178     brouard  10060: #if defined(__GNUC__)
                   10061:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10062: #endif
1.177     brouard  10063: #elif defined(__GNUC__) 
1.179     brouard  10064: #ifndef  __APPLE__
1.174     brouard  10065: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10066: #endif
1.177     brouard  10067:    struct utsname sysInfo;
1.178     brouard  10068:    int cross = CROSS;
                   10069:    if (cross){
                   10070:           printf("Cross-");
1.191     brouard  10071:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10072:    }
1.174     brouard  10073: #endif
                   10074: 
1.171     brouard  10075: #include <stdint.h>
1.178     brouard  10076: 
1.191     brouard  10077:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10078: #if defined(__clang__)
1.191     brouard  10079:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10080: #endif
                   10081: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10082:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10083: #endif
                   10084: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10085:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10086: #endif
                   10087: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10088:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10089: #endif
                   10090: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10091:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10092: #endif
                   10093: #if defined(_MSC_VER)
1.191     brouard  10094:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10095: #endif
                   10096: #if defined(__PGI)
1.191     brouard  10097:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10098: #endif
                   10099: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10100:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10101: #endif
1.191     brouard  10102:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10103:    
1.167     brouard  10104: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10105: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10106:     // Windows (x64 and x86)
1.191     brouard  10107:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10108: #elif __unix__ // all unices, not all compilers
                   10109:     // Unix
1.191     brouard  10110:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10111: #elif __linux__
                   10112:     // linux
1.191     brouard  10113:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10114: #elif __APPLE__
1.174     brouard  10115:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10116:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10117: #endif
                   10118: 
                   10119: /*  __MINGW32__          */
                   10120: /*  __CYGWIN__  */
                   10121: /* __MINGW64__  */
                   10122: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10123: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10124: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10125: /* _WIN64  // Defined for applications for Win64. */
                   10126: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10127: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10128: 
1.167     brouard  10129: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10130:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10131: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10132:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10133: #else
1.191     brouard  10134:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10135: #endif
                   10136: 
1.169     brouard  10137: #if defined(__GNUC__)
                   10138: # if defined(__GNUC_PATCHLEVEL__)
                   10139: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10140:                             + __GNUC_MINOR__ * 100 \
                   10141:                             + __GNUC_PATCHLEVEL__)
                   10142: # else
                   10143: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10144:                             + __GNUC_MINOR__ * 100)
                   10145: # endif
1.174     brouard  10146:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10147:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10148: 
                   10149:    if (uname(&sysInfo) != -1) {
                   10150:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10151:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10152:    }
                   10153:    else
                   10154:       perror("uname() error");
1.179     brouard  10155:    //#ifndef __INTEL_COMPILER 
                   10156: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10157:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10158:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10159: #endif
1.169     brouard  10160: #endif
1.172     brouard  10161: 
                   10162:    //   void main()
                   10163:    //   {
1.169     brouard  10164: #if defined(_MSC_VER)
1.174     brouard  10165:    if (IsWow64()){
1.191     brouard  10166:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10167:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10168:    }
                   10169:    else{
1.191     brouard  10170:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10171:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10172:    }
1.172     brouard  10173:    //     printf("\nPress Enter to continue...");
                   10174:    //     getchar();
                   10175:    //   }
                   10176: 
1.169     brouard  10177: #endif
                   10178:    
1.167     brouard  10179: 
1.219     brouard  10180: }
1.136     brouard  10181: 
1.219     brouard  10182: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10183:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10184:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10185:   /* double ftolpl = 1.e-10; */
1.180     brouard  10186:   double age, agebase, agelim;
1.203     brouard  10187:   double tot;
1.180     brouard  10188: 
1.202     brouard  10189:   strcpy(filerespl,"PL_");
                   10190:   strcat(filerespl,fileresu);
                   10191:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10192:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10193:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10194:   }
1.227     brouard  10195:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10196:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10197:   pstamp(ficrespl);
1.203     brouard  10198:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10199:   fprintf(ficrespl,"#Age ");
                   10200:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10201:   fprintf(ficrespl,"\n");
1.180     brouard  10202:   
1.219     brouard  10203:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10204: 
1.219     brouard  10205:   agebase=ageminpar;
                   10206:   agelim=agemaxpar;
1.180     brouard  10207: 
1.227     brouard  10208:   /* i1=pow(2,ncoveff); */
1.234     brouard  10209:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10210:   if (cptcovn < 1){i1=1;}
1.180     brouard  10211: 
1.238     brouard  10212:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10213:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10214:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10215:        continue;
1.235     brouard  10216: 
1.238     brouard  10217:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10218:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10219:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10220:       /* k=k+1; */
                   10221:       /* to clean */
                   10222:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10223:       fprintf(ficrespl,"#******");
                   10224:       printf("#******");
                   10225:       fprintf(ficlog,"#******");
                   10226:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10227:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10228:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10229:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10230:       }
                   10231:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10232:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10233:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10234:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10235:       }
                   10236:       fprintf(ficrespl,"******\n");
                   10237:       printf("******\n");
                   10238:       fprintf(ficlog,"******\n");
                   10239:       if(invalidvarcomb[k]){
                   10240:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10241:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10242:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10243:        continue;
                   10244:       }
1.219     brouard  10245: 
1.238     brouard  10246:       fprintf(ficrespl,"#Age ");
                   10247:       for(j=1;j<=cptcoveff;j++) {
                   10248:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10249:       }
                   10250:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10251:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10252:     
1.238     brouard  10253:       for (age=agebase; age<=agelim; age++){
                   10254:        /* for (age=agebase; age<=agebase; age++){ */
                   10255:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10256:        fprintf(ficrespl,"%.0f ",age );
                   10257:        for(j=1;j<=cptcoveff;j++)
                   10258:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10259:        tot=0.;
                   10260:        for(i=1; i<=nlstate;i++){
                   10261:          tot +=  prlim[i][i];
                   10262:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10263:        }
                   10264:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10265:       } /* Age */
                   10266:       /* was end of cptcod */
                   10267:     } /* cptcov */
                   10268:   } /* nres */
1.219     brouard  10269:   return 0;
1.180     brouard  10270: }
                   10271: 
1.218     brouard  10272: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10273:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10274:        
                   10275:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10276:    * at any age between ageminpar and agemaxpar
                   10277:         */
1.235     brouard  10278:   int i, j, k, i1, nres=0 ;
1.217     brouard  10279:   /* double ftolpl = 1.e-10; */
                   10280:   double age, agebase, agelim;
                   10281:   double tot;
1.218     brouard  10282:   /* double ***mobaverage; */
                   10283:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10284: 
                   10285:   strcpy(fileresplb,"PLB_");
                   10286:   strcat(fileresplb,fileresu);
                   10287:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10288:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10289:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10290:   }
                   10291:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10292:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10293:   pstamp(ficresplb);
                   10294:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10295:   fprintf(ficresplb,"#Age ");
                   10296:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10297:   fprintf(ficresplb,"\n");
                   10298:   
1.218     brouard  10299:   
                   10300:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10301:   
                   10302:   agebase=ageminpar;
                   10303:   agelim=agemaxpar;
                   10304:   
                   10305:   
1.227     brouard  10306:   i1=pow(2,cptcoveff);
1.218     brouard  10307:   if (cptcovn < 1){i1=1;}
1.227     brouard  10308:   
1.238     brouard  10309:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10310:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10311:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10312:        continue;
                   10313:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10314:       fprintf(ficresplb,"#******");
                   10315:       printf("#******");
                   10316:       fprintf(ficlog,"#******");
                   10317:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10318:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10319:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10320:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10321:       }
                   10322:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10323:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10324:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10325:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10326:       }
                   10327:       fprintf(ficresplb,"******\n");
                   10328:       printf("******\n");
                   10329:       fprintf(ficlog,"******\n");
                   10330:       if(invalidvarcomb[k]){
                   10331:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10332:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10333:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10334:        continue;
                   10335:       }
1.218     brouard  10336:     
1.238     brouard  10337:       fprintf(ficresplb,"#Age ");
                   10338:       for(j=1;j<=cptcoveff;j++) {
                   10339:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10340:       }
                   10341:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10342:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10343:     
                   10344:     
1.238     brouard  10345:       for (age=agebase; age<=agelim; age++){
                   10346:        /* for (age=agebase; age<=agebase; age++){ */
                   10347:        if(mobilavproj > 0){
                   10348:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10349:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10350:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10351:        }else if (mobilavproj == 0){
                   10352:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10353:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10354:          exit(1);
                   10355:        }else{
                   10356:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10357:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10358:          /* printf("TOTOT\n"); */
                   10359:           /* exit(1); */
1.238     brouard  10360:        }
                   10361:        fprintf(ficresplb,"%.0f ",age );
                   10362:        for(j=1;j<=cptcoveff;j++)
                   10363:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10364:        tot=0.;
                   10365:        for(i=1; i<=nlstate;i++){
                   10366:          tot +=  bprlim[i][i];
                   10367:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10368:        }
                   10369:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10370:       } /* Age */
                   10371:       /* was end of cptcod */
1.255     brouard  10372:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10373:     } /* end of any combination */
                   10374:   } /* end of nres */  
1.218     brouard  10375:   /* hBijx(p, bage, fage); */
                   10376:   /* fclose(ficrespijb); */
                   10377:   
                   10378:   return 0;
1.217     brouard  10379: }
1.218     brouard  10380:  
1.180     brouard  10381: int hPijx(double *p, int bage, int fage){
                   10382:     /*------------- h Pij x at various ages ------------*/
                   10383: 
                   10384:   int stepsize;
                   10385:   int agelim;
                   10386:   int hstepm;
                   10387:   int nhstepm;
1.235     brouard  10388:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10389: 
                   10390:   double agedeb;
                   10391:   double ***p3mat;
                   10392: 
1.201     brouard  10393:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10394:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10395:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10396:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10397:     }
                   10398:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10399:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10400:   
                   10401:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10402:     /*if (stepm<=24) stepsize=2;*/
                   10403: 
                   10404:     agelim=AGESUP;
                   10405:     hstepm=stepsize*YEARM; /* Every year of age */
                   10406:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10407:                
1.180     brouard  10408:     /* hstepm=1;   aff par mois*/
                   10409:     pstamp(ficrespij);
                   10410:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10411:     i1= pow(2,cptcoveff);
1.218     brouard  10412:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10413:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10414:                /*      k=k+1;  */
1.235     brouard  10415:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10416:     for(k=1; k<=i1;k++){
1.253     brouard  10417:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10418:        continue;
1.183     brouard  10419:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10420:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10421:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10422:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10423:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10424:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10425:       }
1.183     brouard  10426:       fprintf(ficrespij,"******\n");
                   10427:       
                   10428:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10429:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10430:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10431:        
                   10432:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10433:        
1.183     brouard  10434:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10435:        oldm=oldms;savm=savms;
1.235     brouard  10436:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10437:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10438:        for(i=1; i<=nlstate;i++)
                   10439:          for(j=1; j<=nlstate+ndeath;j++)
                   10440:            fprintf(ficrespij," %1d-%1d",i,j);
                   10441:        fprintf(ficrespij,"\n");
                   10442:        for (h=0; h<=nhstepm; h++){
                   10443:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10444:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10445:          for(i=1; i<=nlstate;i++)
                   10446:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10447:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10448:          fprintf(ficrespij,"\n");
                   10449:        }
1.183     brouard  10450:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10451:        fprintf(ficrespij,"\n");
                   10452:       }
1.180     brouard  10453:       /*}*/
                   10454:     }
1.218     brouard  10455:     return 0;
1.180     brouard  10456: }
1.218     brouard  10457:  
                   10458:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10459:     /*------------- h Bij x at various ages ------------*/
                   10460: 
                   10461:   int stepsize;
1.218     brouard  10462:   /* int agelim; */
                   10463:        int ageminl;
1.217     brouard  10464:   int hstepm;
                   10465:   int nhstepm;
1.238     brouard  10466:   int h, i, i1, j, k, nres;
1.218     brouard  10467:        
1.217     brouard  10468:   double agedeb;
                   10469:   double ***p3mat;
1.218     brouard  10470:        
                   10471:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10472:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10473:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10474:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10475:   }
                   10476:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10477:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10478:   
                   10479:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10480:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10481:   
1.218     brouard  10482:   /* agelim=AGESUP; */
                   10483:   ageminl=30;
                   10484:   hstepm=stepsize*YEARM; /* Every year of age */
                   10485:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10486:   
                   10487:   /* hstepm=1;   aff par mois*/
                   10488:   pstamp(ficrespijb);
1.255     brouard  10489:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10490:   i1= pow(2,cptcoveff);
1.218     brouard  10491:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10492:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10493:   /*   k=k+1;  */
1.238     brouard  10494:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10495:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10496:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10497:        continue;
                   10498:       fprintf(ficrespijb,"\n#****** ");
                   10499:       for(j=1;j<=cptcoveff;j++)
                   10500:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10501:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10502:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10503:       }
                   10504:       fprintf(ficrespijb,"******\n");
1.264     brouard  10505:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10506:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10507:        continue;
                   10508:       }
                   10509:       
                   10510:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10511:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10512:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10513:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10514:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10515:        
                   10516:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10517:        
1.266     brouard  10518:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10519:        /* and memory limitations if stepm is small */
                   10520: 
1.238     brouard  10521:        /* oldm=oldms;savm=savms; */
                   10522:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10523:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10524:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10525:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10526:        for(i=1; i<=nlstate;i++)
                   10527:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10528:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10529:        fprintf(ficrespijb,"\n");
1.238     brouard  10530:        for (h=0; h<=nhstepm; h++){
                   10531:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10532:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10533:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10534:          for(i=1; i<=nlstate;i++)
                   10535:            for(j=1; j<=nlstate+ndeath;j++)
                   10536:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10537:          fprintf(ficrespijb,"\n");
                   10538:        }
                   10539:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10540:        fprintf(ficrespijb,"\n");
                   10541:       } /* end age deb */
                   10542:     } /* end combination */
                   10543:   } /* end nres */
1.218     brouard  10544:   return 0;
                   10545:  } /*  hBijx */
1.217     brouard  10546: 
1.180     brouard  10547: 
1.136     brouard  10548: /***********************************************/
                   10549: /**************** Main Program *****************/
                   10550: /***********************************************/
                   10551: 
                   10552: int main(int argc, char *argv[])
                   10553: {
                   10554: #ifdef GSL
                   10555:   const gsl_multimin_fminimizer_type *T;
                   10556:   size_t iteri = 0, it;
                   10557:   int rval = GSL_CONTINUE;
                   10558:   int status = GSL_SUCCESS;
                   10559:   double ssval;
                   10560: #endif
                   10561:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10562:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10563:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10564:   int jj, ll, li, lj, lk;
1.136     brouard  10565:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10566:   int num_filled;
1.136     brouard  10567:   int itimes;
                   10568:   int NDIM=2;
                   10569:   int vpopbased=0;
1.235     brouard  10570:   int nres=0;
1.258     brouard  10571:   int endishere=0;
1.136     brouard  10572: 
1.164     brouard  10573:   char ca[32], cb[32];
1.136     brouard  10574:   /*  FILE *fichtm; *//* Html File */
                   10575:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10576:   struct stat info;
1.191     brouard  10577:   double agedeb=0.;
1.194     brouard  10578: 
                   10579:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10580:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10581: 
1.165     brouard  10582:   double fret;
1.191     brouard  10583:   double dum=0.; /* Dummy variable */
1.136     brouard  10584:   double ***p3mat;
1.218     brouard  10585:   /* double ***mobaverage; */
1.164     brouard  10586: 
                   10587:   char line[MAXLINE];
1.197     brouard  10588:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10589: 
1.234     brouard  10590:   char  modeltemp[MAXLINE];
1.230     brouard  10591:   char resultline[MAXLINE];
                   10592:   
1.136     brouard  10593:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10594:   char *tok, *val; /* pathtot */
1.136     brouard  10595:   int firstobs=1, lastobs=10;
1.195     brouard  10596:   int c,  h , cpt, c2;
1.191     brouard  10597:   int jl=0;
                   10598:   int i1, j1, jk, stepsize=0;
1.194     brouard  10599:   int count=0;
                   10600: 
1.164     brouard  10601:   int *tab; 
1.136     brouard  10602:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10603:   int backcast=0;
1.136     brouard  10604:   int mobilav=0,popforecast=0;
1.191     brouard  10605:   int hstepm=0, nhstepm=0;
1.136     brouard  10606:   int agemortsup;
                   10607:   float  sumlpop=0.;
                   10608:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10609:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10610: 
1.191     brouard  10611:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10612:   double ftolpl=FTOL;
                   10613:   double **prlim;
1.217     brouard  10614:   double **bprlim;
1.136     brouard  10615:   double ***param; /* Matrix of parameters */
1.251     brouard  10616:   double ***paramstart; /* Matrix of starting parameter values */
                   10617:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10618:   double **matcov; /* Matrix of covariance */
1.203     brouard  10619:   double **hess; /* Hessian matrix */
1.136     brouard  10620:   double ***delti3; /* Scale */
                   10621:   double *delti; /* Scale */
                   10622:   double ***eij, ***vareij;
                   10623:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10624: 
1.136     brouard  10625:   double *epj, vepp;
1.164     brouard  10626: 
1.136     brouard  10627:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  10628:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   10629: 
1.136     brouard  10630:   double **ximort;
1.145     brouard  10631:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10632:   int *dcwave;
                   10633: 
1.164     brouard  10634:   char z[1]="c";
1.136     brouard  10635: 
                   10636:   /*char  *strt;*/
                   10637:   char strtend[80];
1.126     brouard  10638: 
1.164     brouard  10639: 
1.126     brouard  10640: /*   setlocale (LC_ALL, ""); */
                   10641: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10642: /*   textdomain (PACKAGE); */
                   10643: /*   setlocale (LC_CTYPE, ""); */
                   10644: /*   setlocale (LC_MESSAGES, ""); */
                   10645: 
                   10646:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10647:   rstart_time = time(NULL);  
                   10648:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10649:   start_time = *localtime(&rstart_time);
1.126     brouard  10650:   curr_time=start_time;
1.157     brouard  10651:   /*tml = *localtime(&start_time.tm_sec);*/
                   10652:   /* strcpy(strstart,asctime(&tml)); */
                   10653:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10654: 
                   10655: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10656: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10657: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10658: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10659: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10660: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10661: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10662: /*   strt=asctime(&tmg); */
                   10663: /*   printf("Time(after) =%s",strstart);  */
                   10664: /*  (void) time (&time_value);
                   10665: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10666: *  tm = *localtime(&time_value);
                   10667: *  strstart=asctime(&tm);
                   10668: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10669: */
                   10670: 
                   10671:   nberr=0; /* Number of errors and warnings */
                   10672:   nbwarn=0;
1.184     brouard  10673: #ifdef WIN32
                   10674:   _getcwd(pathcd, size);
                   10675: #else
1.126     brouard  10676:   getcwd(pathcd, size);
1.184     brouard  10677: #endif
1.191     brouard  10678:   syscompilerinfo(0);
1.196     brouard  10679:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10680:   if(argc <=1){
                   10681:     printf("\nEnter the parameter file name: ");
1.205     brouard  10682:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10683:       printf("ERROR Empty parameter file name\n");
                   10684:       goto end;
                   10685:     }
1.126     brouard  10686:     i=strlen(pathr);
                   10687:     if(pathr[i-1]=='\n')
                   10688:       pathr[i-1]='\0';
1.156     brouard  10689:     i=strlen(pathr);
1.205     brouard  10690:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10691:       pathr[i-1]='\0';
1.205     brouard  10692:     }
                   10693:     i=strlen(pathr);
                   10694:     if( i==0 ){
                   10695:       printf("ERROR Empty parameter file name\n");
                   10696:       goto end;
                   10697:     }
                   10698:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10699:       printf("Pathr |%s|\n",pathr);
                   10700:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10701:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10702:       strcpy (pathtot, val);
                   10703:       if(pathr[0] == '\0') break; /* Dirty */
                   10704:     }
                   10705:   }
                   10706:   else{
                   10707:     strcpy(pathtot,argv[1]);
                   10708:   }
                   10709:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10710:   /*cygwin_split_path(pathtot,path,optionfile);
                   10711:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10712:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10713: 
                   10714:   /* Split argv[0], imach program to get pathimach */
                   10715:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10716:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10717:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10718:  /*   strcpy(pathimach,argv[0]); */
                   10719:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10720:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10721:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10722: #ifdef WIN32
                   10723:   _chdir(path); /* Can be a relative path */
                   10724:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10725: #else
1.126     brouard  10726:   chdir(path); /* Can be a relative path */
1.184     brouard  10727:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10728: #endif
                   10729:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10730:   strcpy(command,"mkdir ");
                   10731:   strcat(command,optionfilefiname);
                   10732:   if((outcmd=system(command)) != 0){
1.169     brouard  10733:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10734:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10735:     /* fclose(ficlog); */
                   10736: /*     exit(1); */
                   10737:   }
                   10738: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10739: /*     perror("mkdir"); */
                   10740: /*   } */
                   10741: 
                   10742:   /*-------- arguments in the command line --------*/
                   10743: 
1.186     brouard  10744:   /* Main Log file */
1.126     brouard  10745:   strcat(filelog, optionfilefiname);
                   10746:   strcat(filelog,".log");    /* */
                   10747:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10748:     printf("Problem with logfile %s\n",filelog);
                   10749:     goto end;
                   10750:   }
                   10751:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10752:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10753:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10754:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10755:  path=%s \n\
                   10756:  optionfile=%s\n\
                   10757:  optionfilext=%s\n\
1.156     brouard  10758:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10759: 
1.197     brouard  10760:   syscompilerinfo(1);
1.167     brouard  10761: 
1.126     brouard  10762:   printf("Local time (at start):%s",strstart);
                   10763:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10764:   fflush(ficlog);
                   10765: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10766: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10767: 
                   10768:   /* */
                   10769:   strcpy(fileres,"r");
                   10770:   strcat(fileres, optionfilefiname);
1.201     brouard  10771:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10772:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10773:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10774: 
1.186     brouard  10775:   /* Main ---------arguments file --------*/
1.126     brouard  10776: 
                   10777:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10778:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10779:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10780:     fflush(ficlog);
1.149     brouard  10781:     /* goto end; */
                   10782:     exit(70); 
1.126     brouard  10783:   }
                   10784: 
                   10785: 
                   10786: 
                   10787:   strcpy(filereso,"o");
1.201     brouard  10788:   strcat(filereso,fileresu);
1.126     brouard  10789:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10790:     printf("Problem with Output resultfile: %s\n", filereso);
                   10791:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10792:     fflush(ficlog);
                   10793:     goto end;
                   10794:   }
                   10795: 
                   10796:   /* Reads comments: lines beginning with '#' */
                   10797:   numlinepar=0;
1.197     brouard  10798: 
                   10799:     /* First parameter line */
                   10800:   while(fgets(line, MAXLINE, ficpar)) {
                   10801:     /* If line starts with a # it is a comment */
                   10802:     if (line[0] == '#') {
                   10803:       numlinepar++;
                   10804:       fputs(line,stdout);
                   10805:       fputs(line,ficparo);
                   10806:       fputs(line,ficlog);
                   10807:       continue;
                   10808:     }else
                   10809:       break;
                   10810:   }
                   10811:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10812:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10813:     if (num_filled != 5) {
                   10814:       printf("Should be 5 parameters\n");
                   10815:     }
1.126     brouard  10816:     numlinepar++;
1.197     brouard  10817:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10818:   }
                   10819:   /* Second parameter line */
                   10820:   while(fgets(line, MAXLINE, ficpar)) {
                   10821:     /* If line starts with a # it is a comment */
                   10822:     if (line[0] == '#') {
                   10823:       numlinepar++;
                   10824:       fputs(line,stdout);
                   10825:       fputs(line,ficparo);
                   10826:       fputs(line,ficlog);
                   10827:       continue;
                   10828:     }else
                   10829:       break;
                   10830:   }
1.223     brouard  10831:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10832:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10833:     if (num_filled != 11) {
                   10834:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10835:       printf("but line=%s\n",line);
1.197     brouard  10836:     }
1.223     brouard  10837:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10838:   }
1.203     brouard  10839:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10840:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10841:   /* Third parameter line */
                   10842:   while(fgets(line, MAXLINE, ficpar)) {
                   10843:     /* If line starts with a # it is a comment */
                   10844:     if (line[0] == '#') {
                   10845:       numlinepar++;
                   10846:       fputs(line,stdout);
                   10847:       fputs(line,ficparo);
                   10848:       fputs(line,ficlog);
                   10849:       continue;
                   10850:     }else
                   10851:       break;
                   10852:   }
1.201     brouard  10853:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10854:     if (num_filled == 0){
                   10855:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10856:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10857:       model[0]='\0';
                   10858:       goto end;
                   10859:     } else if (num_filled != 1){
1.197     brouard  10860:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10861:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10862:       model[0]='\0';
                   10863:       goto end;
                   10864:     }
                   10865:     else{
                   10866:       if (model[0]=='+'){
                   10867:        for(i=1; i<=strlen(model);i++)
                   10868:          modeltemp[i-1]=model[i];
1.201     brouard  10869:        strcpy(model,modeltemp); 
1.197     brouard  10870:       }
                   10871:     }
1.199     brouard  10872:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10873:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10874:   }
                   10875:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10876:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10877:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10878:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10879:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10880:   fflush(ficlog);
1.190     brouard  10881:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10882:   if(model[0]=='#'){
1.187     brouard  10883:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10884:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10885:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10886:     if(mle != -1){
                   10887:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10888:       exit(1);
                   10889:     }
                   10890:   }
1.126     brouard  10891:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10892:     ungetc(c,ficpar);
                   10893:     fgets(line, MAXLINE, ficpar);
                   10894:     numlinepar++;
1.195     brouard  10895:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10896:       z[0]=line[1];
                   10897:     }
                   10898:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10899:     fputs(line, stdout);
                   10900:     //puts(line);
1.126     brouard  10901:     fputs(line,ficparo);
                   10902:     fputs(line,ficlog);
                   10903:   }
                   10904:   ungetc(c,ficpar);
                   10905: 
                   10906:    
1.145     brouard  10907:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10908:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10909:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10910:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10911:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10912:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10913:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10914:   */
                   10915:   if (strlen(model)>1) 
1.187     brouard  10916:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10917:   else
1.187     brouard  10918:     ncovmodel=2; /* Constant and age */
1.133     brouard  10919:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10920:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10921:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10922:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10923:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10924:     fflush(stdout);
                   10925:     fclose (ficlog);
                   10926:     goto end;
                   10927:   }
1.126     brouard  10928:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10929:   delti=delti3[1][1];
                   10930:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10931:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10932: /* We could also provide initial parameters values giving by simple logistic regression 
                   10933:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10934:       /* for(i=1;i<nlstate;i++){ */
                   10935:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10936:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10937:       /* } */
1.126     brouard  10938:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10939:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10940:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10941:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10942:     fclose (ficparo);
                   10943:     fclose (ficlog);
                   10944:     goto end;
                   10945:     exit(0);
1.220     brouard  10946:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10947:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10948:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10949:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10950:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10951:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10952:     hess=matrix(1,npar,1,npar);
1.220     brouard  10953:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10954:     /* Read guessed parameters */
1.126     brouard  10955:     /* Reads comments: lines beginning with '#' */
                   10956:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10957:       ungetc(c,ficpar);
                   10958:       fgets(line, MAXLINE, ficpar);
                   10959:       numlinepar++;
1.141     brouard  10960:       fputs(line,stdout);
1.126     brouard  10961:       fputs(line,ficparo);
                   10962:       fputs(line,ficlog);
                   10963:     }
                   10964:     ungetc(c,ficpar);
                   10965:     
                   10966:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10967:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10968:     for(i=1; i <=nlstate; i++){
1.234     brouard  10969:       j=0;
1.126     brouard  10970:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10971:        if(jj==i) continue;
                   10972:        j++;
                   10973:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10974:        if ((i1 != i) || (j1 != jj)){
                   10975:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10976: It might be a problem of design; if ncovcol and the model are correct\n \
                   10977: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10978:          exit(1);
                   10979:        }
                   10980:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10981:        if(mle==1)
                   10982:          printf("%1d%1d",i,jj);
                   10983:        fprintf(ficlog,"%1d%1d",i,jj);
                   10984:        for(k=1; k<=ncovmodel;k++){
                   10985:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10986:          if(mle==1){
                   10987:            printf(" %lf",param[i][j][k]);
                   10988:            fprintf(ficlog," %lf",param[i][j][k]);
                   10989:          }
                   10990:          else
                   10991:            fprintf(ficlog," %lf",param[i][j][k]);
                   10992:          fprintf(ficparo," %lf",param[i][j][k]);
                   10993:        }
                   10994:        fscanf(ficpar,"\n");
                   10995:        numlinepar++;
                   10996:        if(mle==1)
                   10997:          printf("\n");
                   10998:        fprintf(ficlog,"\n");
                   10999:        fprintf(ficparo,"\n");
1.126     brouard  11000:       }
                   11001:     }  
                   11002:     fflush(ficlog);
1.234     brouard  11003:     
1.251     brouard  11004:     /* Reads parameters values */
1.126     brouard  11005:     p=param[1][1];
1.251     brouard  11006:     pstart=paramstart[1][1];
1.126     brouard  11007:     
                   11008:     /* Reads comments: lines beginning with '#' */
                   11009:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11010:       ungetc(c,ficpar);
                   11011:       fgets(line, MAXLINE, ficpar);
                   11012:       numlinepar++;
1.141     brouard  11013:       fputs(line,stdout);
1.126     brouard  11014:       fputs(line,ficparo);
                   11015:       fputs(line,ficlog);
                   11016:     }
                   11017:     ungetc(c,ficpar);
                   11018: 
                   11019:     for(i=1; i <=nlstate; i++){
                   11020:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11021:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11022:        if ( (i1-i) * (j1-j) != 0){
                   11023:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11024:          exit(1);
                   11025:        }
                   11026:        printf("%1d%1d",i,j);
                   11027:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11028:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11029:        for(k=1; k<=ncovmodel;k++){
                   11030:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11031:          printf(" %le",delti3[i][j][k]);
                   11032:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11033:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11034:        }
                   11035:        fscanf(ficpar,"\n");
                   11036:        numlinepar++;
                   11037:        printf("\n");
                   11038:        fprintf(ficparo,"\n");
                   11039:        fprintf(ficlog,"\n");
1.126     brouard  11040:       }
                   11041:     }
                   11042:     fflush(ficlog);
1.234     brouard  11043:     
1.145     brouard  11044:     /* Reads covariance matrix */
1.126     brouard  11045:     delti=delti3[1][1];
1.220     brouard  11046:                
                   11047:                
1.126     brouard  11048:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11049:                
1.126     brouard  11050:     /* Reads comments: lines beginning with '#' */
                   11051:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11052:       ungetc(c,ficpar);
                   11053:       fgets(line, MAXLINE, ficpar);
                   11054:       numlinepar++;
1.141     brouard  11055:       fputs(line,stdout);
1.126     brouard  11056:       fputs(line,ficparo);
                   11057:       fputs(line,ficlog);
                   11058:     }
                   11059:     ungetc(c,ficpar);
1.220     brouard  11060:                
1.126     brouard  11061:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11062:     hess=matrix(1,npar,1,npar);
1.131     brouard  11063:     for(i=1; i <=npar; i++)
                   11064:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11065:                
1.194     brouard  11066:     /* Scans npar lines */
1.126     brouard  11067:     for(i=1; i <=npar; i++){
1.226     brouard  11068:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11069:       if(count != 3){
1.226     brouard  11070:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11071: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11072: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11073:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11074: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11075: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11076:        exit(1);
1.220     brouard  11077:       }else{
1.226     brouard  11078:        if(mle==1)
                   11079:          printf("%1d%1d%d",i1,j1,jk);
                   11080:       }
                   11081:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11082:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11083:       for(j=1; j <=i; j++){
1.226     brouard  11084:        fscanf(ficpar," %le",&matcov[i][j]);
                   11085:        if(mle==1){
                   11086:          printf(" %.5le",matcov[i][j]);
                   11087:        }
                   11088:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11089:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11090:       }
                   11091:       fscanf(ficpar,"\n");
                   11092:       numlinepar++;
                   11093:       if(mle==1)
1.220     brouard  11094:                                printf("\n");
1.126     brouard  11095:       fprintf(ficlog,"\n");
                   11096:       fprintf(ficparo,"\n");
                   11097:     }
1.194     brouard  11098:     /* End of read covariance matrix npar lines */
1.126     brouard  11099:     for(i=1; i <=npar; i++)
                   11100:       for(j=i+1;j<=npar;j++)
1.226     brouard  11101:        matcov[i][j]=matcov[j][i];
1.126     brouard  11102:     
                   11103:     if(mle==1)
                   11104:       printf("\n");
                   11105:     fprintf(ficlog,"\n");
                   11106:     
                   11107:     fflush(ficlog);
                   11108:     
                   11109:     /*-------- Rewriting parameter file ----------*/
                   11110:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11111:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11112:     strcat(rfileres,".");    /* */
                   11113:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11114:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11115:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11116:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11117:     }
                   11118:     fprintf(ficres,"#%s\n",version);
                   11119:   }    /* End of mle != -3 */
1.218     brouard  11120:   
1.186     brouard  11121:   /*  Main data
                   11122:    */
1.126     brouard  11123:   n= lastobs;
                   11124:   num=lvector(1,n);
                   11125:   moisnais=vector(1,n);
                   11126:   annais=vector(1,n);
                   11127:   moisdc=vector(1,n);
                   11128:   andc=vector(1,n);
1.220     brouard  11129:   weight=vector(1,n);
1.126     brouard  11130:   agedc=vector(1,n);
                   11131:   cod=ivector(1,n);
1.220     brouard  11132:   for(i=1;i<=n;i++){
1.234     brouard  11133:     num[i]=0;
                   11134:     moisnais[i]=0;
                   11135:     annais[i]=0;
                   11136:     moisdc[i]=0;
                   11137:     andc[i]=0;
                   11138:     agedc[i]=0;
                   11139:     cod[i]=0;
                   11140:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11141:   }
1.126     brouard  11142:   mint=matrix(1,maxwav,1,n);
                   11143:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11144:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11145:   tab=ivector(1,NCOVMAX);
1.144     brouard  11146:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11147:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11148: 
1.136     brouard  11149:   /* Reads data from file datafile */
                   11150:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11151:     goto end;
                   11152: 
                   11153:   /* Calculation of the number of parameters from char model */
1.234     brouard  11154:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11155:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11156:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11157:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11158:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11159:   */
                   11160:   
                   11161:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11162:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11163:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11164:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11165:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11166:   TvarF=ivector(1,NCOVMAX); /*  */
                   11167:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11168:   TvarV=ivector(1,NCOVMAX); /*  */
                   11169:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11170:   TvarA=ivector(1,NCOVMAX); /*  */
                   11171:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11172:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11173:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11174:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11175:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11176:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11177:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11178:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11179:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11180: 
1.230     brouard  11181:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11182:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11183:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11184:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11185:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11186:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11187:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11188:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11189:   */
                   11190:   /* For model-covariate k tells which data-covariate to use but
                   11191:     because this model-covariate is a construction we invent a new column
                   11192:     ncovcol + k1
                   11193:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11194:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11195:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11196:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11197:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11198:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11199:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11200:   */
1.145     brouard  11201:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11202:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11203:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11204:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11205:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11206:                         4 covariates (3 plus signs)
                   11207:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11208:                      */  
1.230     brouard  11209:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11210:                                * individual dummy, fixed or varying:
                   11211:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11212:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11213:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11214:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11215:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11216:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11217:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11218:                                * individual quantitative, fixed or varying:
                   11219:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11220:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11221:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11222: /* Main decodemodel */
                   11223: 
1.187     brouard  11224: 
1.223     brouard  11225:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11226:     goto end;
                   11227: 
1.137     brouard  11228:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11229:     nbwarn++;
                   11230:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11231:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11232:   }
1.136     brouard  11233:     /*  if(mle==1){*/
1.137     brouard  11234:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11235:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11236:   }
                   11237: 
                   11238:     /*-calculation of age at interview from date of interview and age at death -*/
                   11239:   agev=matrix(1,maxwav,1,imx);
                   11240: 
                   11241:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11242:     goto end;
                   11243: 
1.126     brouard  11244: 
1.136     brouard  11245:   agegomp=(int)agemin;
                   11246:   free_vector(moisnais,1,n);
                   11247:   free_vector(annais,1,n);
1.126     brouard  11248:   /* free_matrix(mint,1,maxwav,1,n);
                   11249:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11250:   /* free_vector(moisdc,1,n); */
                   11251:   /* free_vector(andc,1,n); */
1.145     brouard  11252:   /* */
                   11253:   
1.126     brouard  11254:   wav=ivector(1,imx);
1.214     brouard  11255:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11256:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11257:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11258:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11259:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11260:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11261:    
                   11262:   /* Concatenates waves */
1.214     brouard  11263:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11264:      Death is a valid wave (if date is known).
                   11265:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11266:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11267:      and mw[mi+1][i]. dh depends on stepm.
                   11268:   */
                   11269: 
1.126     brouard  11270:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11271:   /* Concatenates waves */
1.145     brouard  11272:  
1.215     brouard  11273:   free_vector(moisdc,1,n);
                   11274:   free_vector(andc,1,n);
                   11275: 
1.126     brouard  11276:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11277:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11278:   ncodemax[1]=1;
1.145     brouard  11279:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11280:   cptcoveff=0;
1.220     brouard  11281:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11282:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11283:   }
                   11284:   
                   11285:   ncovcombmax=pow(2,cptcoveff);
                   11286:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11287:   for(i=1;i<ncovcombmax;i++)
                   11288:     invalidvarcomb[i]=0;
                   11289:   
1.211     brouard  11290:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11291:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11292:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11293:   
1.200     brouard  11294:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11295:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11296:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11297:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11298:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11299:    * (currently 0 or 1) in the data.
                   11300:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11301:    * corresponding modality (h,j).
                   11302:    */
                   11303: 
1.145     brouard  11304:   h=0;
                   11305:   /*if (cptcovn > 0) */
1.126     brouard  11306:   m=pow(2,cptcoveff);
                   11307:  
1.144     brouard  11308:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11309:           * For k=4 covariates, h goes from 1 to m=2**k
                   11310:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11311:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11312:           *     h\k   1     2     3     4
1.143     brouard  11313:           *______________________________  
                   11314:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11315:           *     2     2     1     1     1
                   11316:           *     3 i=2 1     2     1     1
                   11317:           *     4     2     2     1     1
                   11318:           *     5 i=3 1 i=2 1     2     1
                   11319:           *     6     2     1     2     1
                   11320:           *     7 i=4 1     2     2     1
                   11321:           *     8     2     2     2     1
1.197     brouard  11322:           *     9 i=5 1 i=3 1 i=2 1     2
                   11323:           *    10     2     1     1     2
                   11324:           *    11 i=6 1     2     1     2
                   11325:           *    12     2     2     1     2
                   11326:           *    13 i=7 1 i=4 1     2     2    
                   11327:           *    14     2     1     2     2
                   11328:           *    15 i=8 1     2     2     2
                   11329:           *    16     2     2     2     2
1.143     brouard  11330:           */
1.212     brouard  11331:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11332:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11333:      * and the value of each covariate?
                   11334:      * V1=1, V2=1, V3=2, V4=1 ?
                   11335:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11336:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11337:      * In order to get the real value in the data, we use nbcode
                   11338:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11339:      * We are keeping this crazy system in order to be able (in the future?) 
                   11340:      * to have more than 2 values (0 or 1) for a covariate.
                   11341:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11342:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11343:      *              bbbbbbbb
                   11344:      *              76543210     
                   11345:      *   h-1        00000101 (6-1=5)
1.219     brouard  11346:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11347:      *           &
                   11348:      *     1        00000001 (1)
1.219     brouard  11349:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11350:      *          +1= 00000001 =1 
1.211     brouard  11351:      *
                   11352:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11353:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11354:      *    >>k'            11
                   11355:      *          &   00000001
                   11356:      *            = 00000001
                   11357:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11358:      * Reverse h=6 and m=16?
                   11359:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11360:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11361:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11362:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11363:      * V3=decodtabm(14,3,2**4)=2
                   11364:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11365:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11366:      *          &1 000000001
                   11367:      *           = 000000001
                   11368:      *         +1= 000000010 =2
                   11369:      *                  2211
                   11370:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11371:      *                  V3=2
1.220     brouard  11372:                 * codtabm and decodtabm are identical
1.211     brouard  11373:      */
                   11374: 
1.145     brouard  11375: 
                   11376:  free_ivector(Ndum,-1,NCOVMAX);
                   11377: 
                   11378: 
1.126     brouard  11379:     
1.186     brouard  11380:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11381:   strcpy(optionfilegnuplot,optionfilefiname);
                   11382:   if(mle==-3)
1.201     brouard  11383:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11384:   strcat(optionfilegnuplot,".gp");
                   11385: 
                   11386:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11387:     printf("Problem with file %s",optionfilegnuplot);
                   11388:   }
                   11389:   else{
1.204     brouard  11390:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11391:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11392:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11393:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11394:   }
                   11395:   /*  fclose(ficgp);*/
1.186     brouard  11396: 
                   11397: 
                   11398:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11399: 
                   11400:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11401:   if(mle==-3)
1.201     brouard  11402:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11403:   strcat(optionfilehtm,".htm");
                   11404:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11405:     printf("Problem with %s \n",optionfilehtm);
                   11406:     exit(0);
1.126     brouard  11407:   }
                   11408: 
                   11409:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11410:   strcat(optionfilehtmcov,"-cov.htm");
                   11411:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11412:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11413:   }
                   11414:   else{
                   11415:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11416: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11417: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11418:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11419:   }
                   11420: 
1.213     brouard  11421:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11422: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11423: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11424: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11425: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11426: \n\
                   11427: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11428:  <ul><li><h4>Parameter files</h4>\n\
                   11429:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11430:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11431:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11432:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11433:  - Date and time at start: %s</ul>\n",\
                   11434:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11435:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11436:          fileres,fileres,\
                   11437:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11438:   fflush(fichtm);
                   11439: 
                   11440:   strcpy(pathr,path);
                   11441:   strcat(pathr,optionfilefiname);
1.184     brouard  11442: #ifdef WIN32
                   11443:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11444: #else
1.126     brouard  11445:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11446: #endif
                   11447:          
1.126     brouard  11448:   
1.220     brouard  11449:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11450:                 and for any valid combination of covariates
1.126     brouard  11451:      and prints on file fileres'p'. */
1.251     brouard  11452:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11453:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11454: 
                   11455:   fprintf(fichtm,"\n");
                   11456:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   11457: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11458: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   11459:          imx,agemin,agemax,jmin,jmax,jmean);
                   11460:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11461:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11462:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11463:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11464:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11465: 
1.126     brouard  11466:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11467:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11468:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11469: 
                   11470:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11471:   /* For mortality only */
1.126     brouard  11472:   if (mle==-3){
1.136     brouard  11473:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11474:     for(i=1;i<=NDIM;i++)
                   11475:       for(j=1;j<=NDIM;j++)
                   11476:        ximort[i][j]=0.;
1.186     brouard  11477:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11478:     cens=ivector(1,n);
                   11479:     ageexmed=vector(1,n);
                   11480:     agecens=vector(1,n);
                   11481:     dcwave=ivector(1,n);
1.223     brouard  11482:                
1.126     brouard  11483:     for (i=1; i<=imx; i++){
                   11484:       dcwave[i]=-1;
                   11485:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11486:        if (s[m][i]>nlstate) {
                   11487:          dcwave[i]=m;
                   11488:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11489:          break;
                   11490:        }
1.126     brouard  11491:     }
1.226     brouard  11492:     
1.126     brouard  11493:     for (i=1; i<=imx; i++) {
                   11494:       if (wav[i]>0){
1.226     brouard  11495:        ageexmed[i]=agev[mw[1][i]][i];
                   11496:        j=wav[i];
                   11497:        agecens[i]=1.; 
                   11498:        
                   11499:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11500:          agecens[i]=agev[mw[j][i]][i];
                   11501:          cens[i]= 1;
                   11502:        }else if (ageexmed[i]< 1) 
                   11503:          cens[i]= -1;
                   11504:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11505:          cens[i]=0 ;
1.126     brouard  11506:       }
                   11507:       else cens[i]=-1;
                   11508:     }
                   11509:     
                   11510:     for (i=1;i<=NDIM;i++) {
                   11511:       for (j=1;j<=NDIM;j++)
1.226     brouard  11512:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11513:     }
                   11514:     
1.145     brouard  11515:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11516:     /*printf("%lf %lf", p[1], p[2]);*/
                   11517:     
                   11518:     
1.136     brouard  11519: #ifdef GSL
                   11520:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11521: #else
1.126     brouard  11522:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11523: #endif
1.201     brouard  11524:     strcpy(filerespow,"POW-MORT_"); 
                   11525:     strcat(filerespow,fileresu);
1.126     brouard  11526:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11527:       printf("Problem with resultfile: %s\n", filerespow);
                   11528:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11529:     }
1.136     brouard  11530: #ifdef GSL
                   11531:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11532: #else
1.126     brouard  11533:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11534: #endif
1.126     brouard  11535:     /*  for (i=1;i<=nlstate;i++)
                   11536:        for(j=1;j<=nlstate+ndeath;j++)
                   11537:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11538:     */
                   11539:     fprintf(ficrespow,"\n");
1.136     brouard  11540: #ifdef GSL
                   11541:     /* gsl starts here */ 
                   11542:     T = gsl_multimin_fminimizer_nmsimplex;
                   11543:     gsl_multimin_fminimizer *sfm = NULL;
                   11544:     gsl_vector *ss, *x;
                   11545:     gsl_multimin_function minex_func;
                   11546: 
                   11547:     /* Initial vertex size vector */
                   11548:     ss = gsl_vector_alloc (NDIM);
                   11549:     
                   11550:     if (ss == NULL){
                   11551:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11552:     }
                   11553:     /* Set all step sizes to 1 */
                   11554:     gsl_vector_set_all (ss, 0.001);
                   11555: 
                   11556:     /* Starting point */
1.126     brouard  11557:     
1.136     brouard  11558:     x = gsl_vector_alloc (NDIM);
                   11559:     
                   11560:     if (x == NULL){
                   11561:       gsl_vector_free(ss);
                   11562:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11563:     }
                   11564:   
                   11565:     /* Initialize method and iterate */
                   11566:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11567:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11568:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11569:     gsl_vector_set(x, 0, p[1]);
                   11570:     gsl_vector_set(x, 1, p[2]);
                   11571: 
                   11572:     minex_func.f = &gompertz_f;
                   11573:     minex_func.n = NDIM;
                   11574:     minex_func.params = (void *)&p; /* ??? */
                   11575:     
                   11576:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11577:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11578:     
                   11579:     printf("Iterations beginning .....\n\n");
                   11580:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11581: 
                   11582:     iteri=0;
                   11583:     while (rval == GSL_CONTINUE){
                   11584:       iteri++;
                   11585:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11586:       
                   11587:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11588:       fflush(0);
                   11589:       
                   11590:       if (status) 
                   11591:         break;
                   11592:       
                   11593:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11594:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11595:       
                   11596:       if (rval == GSL_SUCCESS)
                   11597:         printf ("converged to a local maximum at\n");
                   11598:       
                   11599:       printf("%5d ", iteri);
                   11600:       for (it = 0; it < NDIM; it++){
                   11601:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11602:       }
                   11603:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11604:     }
                   11605:     
                   11606:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11607:     
                   11608:     gsl_vector_free(x); /* initial values */
                   11609:     gsl_vector_free(ss); /* inital step size */
                   11610:     for (it=0; it<NDIM; it++){
                   11611:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11612:       fprintf(ficrespow," %.12lf", p[it]);
                   11613:     }
                   11614:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11615: #endif
                   11616: #ifdef POWELL
                   11617:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11618: #endif  
1.126     brouard  11619:     fclose(ficrespow);
                   11620:     
1.203     brouard  11621:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11622: 
                   11623:     for(i=1; i <=NDIM; i++)
                   11624:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11625:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11626:     
                   11627:     printf("\nCovariance matrix\n ");
1.203     brouard  11628:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11629:     for(i=1; i <=NDIM; i++) {
                   11630:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11631:                                printf("%f ",matcov[i][j]);
                   11632:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11633:       }
1.203     brouard  11634:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11635:     }
                   11636:     
                   11637:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11638:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11639:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11640:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11641:     }
1.126     brouard  11642:     lsurv=vector(1,AGESUP);
                   11643:     lpop=vector(1,AGESUP);
                   11644:     tpop=vector(1,AGESUP);
                   11645:     lsurv[agegomp]=100000;
                   11646:     
                   11647:     for (k=agegomp;k<=AGESUP;k++) {
                   11648:       agemortsup=k;
                   11649:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11650:     }
                   11651:     
                   11652:     for (k=agegomp;k<agemortsup;k++)
                   11653:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11654:     
                   11655:     for (k=agegomp;k<agemortsup;k++){
                   11656:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11657:       sumlpop=sumlpop+lpop[k];
                   11658:     }
                   11659:     
                   11660:     tpop[agegomp]=sumlpop;
                   11661:     for (k=agegomp;k<(agemortsup-3);k++){
                   11662:       /*  tpop[k+1]=2;*/
                   11663:       tpop[k+1]=tpop[k]-lpop[k];
                   11664:     }
                   11665:     
                   11666:     
                   11667:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11668:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11669:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11670:     
                   11671:     
                   11672:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11673:                ageminpar=50;
                   11674:                agemaxpar=100;
1.194     brouard  11675:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11676:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11677: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11678: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11679:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11680: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11681: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11682:     }else{
                   11683:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11684:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11685:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11686:                }
1.201     brouard  11687:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11688:                     stepm, weightopt,\
                   11689:                     model,imx,p,matcov,agemortsup);
                   11690:     
                   11691:     free_vector(lsurv,1,AGESUP);
                   11692:     free_vector(lpop,1,AGESUP);
                   11693:     free_vector(tpop,1,AGESUP);
1.220     brouard  11694:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11695:     free_ivector(cens,1,n);
                   11696:     free_vector(agecens,1,n);
                   11697:     free_ivector(dcwave,1,n);
1.220     brouard  11698: #ifdef GSL
1.136     brouard  11699: #endif
1.186     brouard  11700:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11701:   /* Standard  */
                   11702:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11703:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11704:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11705:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11706:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11707:     for (k=1; k<=npar;k++)
                   11708:       printf(" %d %8.5f",k,p[k]);
                   11709:     printf("\n");
1.205     brouard  11710:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11711:       /* mlikeli uses func not funcone */
1.247     brouard  11712:       /* for(i=1;i<nlstate;i++){ */
                   11713:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11714:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11715:       /* } */
1.205     brouard  11716:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11717:     }
                   11718:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11719:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11720:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11721:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11722:     }
                   11723:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11724:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11725:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11726:     for (k=1; k<=npar;k++)
                   11727:       printf(" %d %8.5f",k,p[k]);
                   11728:     printf("\n");
                   11729:     
                   11730:     /*--------- results files --------------*/
1.224     brouard  11731:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11732:     
                   11733:     
                   11734:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11735:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11736:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11737:     for(i=1,jk=1; i <=nlstate; i++){
                   11738:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11739:        if (k != i) {
                   11740:          printf("%d%d ",i,k);
                   11741:          fprintf(ficlog,"%d%d ",i,k);
                   11742:          fprintf(ficres,"%1d%1d ",i,k);
                   11743:          for(j=1; j <=ncovmodel; j++){
                   11744:            printf("%12.7f ",p[jk]);
                   11745:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11746:            fprintf(ficres,"%12.7f ",p[jk]);
                   11747:            jk++; 
                   11748:          }
                   11749:          printf("\n");
                   11750:          fprintf(ficlog,"\n");
                   11751:          fprintf(ficres,"\n");
                   11752:        }
1.126     brouard  11753:       }
                   11754:     }
1.203     brouard  11755:     if(mle != 0){
                   11756:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11757:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11758:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11759:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11760:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11761:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11762:        for(k=1; k <=(nlstate+ndeath); k++){
                   11763:          if (k != i) {
                   11764:            printf("%d%d ",i,k);
                   11765:            fprintf(ficlog,"%d%d ",i,k);
                   11766:            for(j=1; j <=ncovmodel; j++){
                   11767:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11768:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11769:              jk++; 
                   11770:            }
                   11771:            printf("\n");
                   11772:            fprintf(ficlog,"\n");
                   11773:          }
                   11774:        }
1.193     brouard  11775:       }
1.203     brouard  11776:     } /* end of hesscov and Wald tests */
1.225     brouard  11777:     
1.203     brouard  11778:     /*  */
1.126     brouard  11779:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11780:     printf("# Scales (for hessian or gradient estimation)\n");
                   11781:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11782:     for(i=1,jk=1; i <=nlstate; i++){
                   11783:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11784:        if (j!=i) {
                   11785:          fprintf(ficres,"%1d%1d",i,j);
                   11786:          printf("%1d%1d",i,j);
                   11787:          fprintf(ficlog,"%1d%1d",i,j);
                   11788:          for(k=1; k<=ncovmodel;k++){
                   11789:            printf(" %.5e",delti[jk]);
                   11790:            fprintf(ficlog," %.5e",delti[jk]);
                   11791:            fprintf(ficres," %.5e",delti[jk]);
                   11792:            jk++;
                   11793:          }
                   11794:          printf("\n");
                   11795:          fprintf(ficlog,"\n");
                   11796:          fprintf(ficres,"\n");
                   11797:        }
1.126     brouard  11798:       }
                   11799:     }
                   11800:     
                   11801:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11802:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11803:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11804:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11805:     /* # 121 Var(a12)\n\ */
                   11806:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11807:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11808:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11809:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11810:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11811:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11812:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11813:     
                   11814:     
                   11815:     /* Just to have a covariance matrix which will be more understandable
                   11816:        even is we still don't want to manage dictionary of variables
                   11817:     */
                   11818:     for(itimes=1;itimes<=2;itimes++){
                   11819:       jj=0;
                   11820:       for(i=1; i <=nlstate; i++){
1.225     brouard  11821:        for(j=1; j <=nlstate+ndeath; j++){
                   11822:          if(j==i) continue;
                   11823:          for(k=1; k<=ncovmodel;k++){
                   11824:            jj++;
                   11825:            ca[0]= k+'a'-1;ca[1]='\0';
                   11826:            if(itimes==1){
                   11827:              if(mle>=1)
                   11828:                printf("#%1d%1d%d",i,j,k);
                   11829:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11830:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11831:            }else{
                   11832:              if(mle>=1)
                   11833:                printf("%1d%1d%d",i,j,k);
                   11834:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11835:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11836:            }
                   11837:            ll=0;
                   11838:            for(li=1;li <=nlstate; li++){
                   11839:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11840:                if(lj==li) continue;
                   11841:                for(lk=1;lk<=ncovmodel;lk++){
                   11842:                  ll++;
                   11843:                  if(ll<=jj){
                   11844:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11845:                    if(ll<jj){
                   11846:                      if(itimes==1){
                   11847:                        if(mle>=1)
                   11848:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11849:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11850:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11851:                      }else{
                   11852:                        if(mle>=1)
                   11853:                          printf(" %.5e",matcov[jj][ll]); 
                   11854:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11855:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11856:                      }
                   11857:                    }else{
                   11858:                      if(itimes==1){
                   11859:                        if(mle>=1)
                   11860:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11861:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11862:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11863:                      }else{
                   11864:                        if(mle>=1)
                   11865:                          printf(" %.7e",matcov[jj][ll]); 
                   11866:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11867:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11868:                      }
                   11869:                    }
                   11870:                  }
                   11871:                } /* end lk */
                   11872:              } /* end lj */
                   11873:            } /* end li */
                   11874:            if(mle>=1)
                   11875:              printf("\n");
                   11876:            fprintf(ficlog,"\n");
                   11877:            fprintf(ficres,"\n");
                   11878:            numlinepar++;
                   11879:          } /* end k*/
                   11880:        } /*end j */
1.126     brouard  11881:       } /* end i */
                   11882:     } /* end itimes */
                   11883:     
                   11884:     fflush(ficlog);
                   11885:     fflush(ficres);
1.225     brouard  11886:     while(fgets(line, MAXLINE, ficpar)) {
                   11887:       /* If line starts with a # it is a comment */
                   11888:       if (line[0] == '#') {
                   11889:        numlinepar++;
                   11890:        fputs(line,stdout);
                   11891:        fputs(line,ficparo);
                   11892:        fputs(line,ficlog);
                   11893:        continue;
                   11894:       }else
                   11895:        break;
                   11896:     }
                   11897:     
1.209     brouard  11898:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11899:     /*   ungetc(c,ficpar); */
                   11900:     /*   fgets(line, MAXLINE, ficpar); */
                   11901:     /*   fputs(line,stdout); */
                   11902:     /*   fputs(line,ficparo); */
                   11903:     /* } */
                   11904:     /* ungetc(c,ficpar); */
1.126     brouard  11905:     
                   11906:     estepm=0;
1.209     brouard  11907:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11908:       
                   11909:       if (num_filled != 6) {
                   11910:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11911:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11912:        goto end;
                   11913:       }
                   11914:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11915:     }
                   11916:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11917:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11918:     
1.209     brouard  11919:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11920:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11921:     if (fage <= 2) {
                   11922:       bage = ageminpar;
                   11923:       fage = agemaxpar;
                   11924:     }
                   11925:     
                   11926:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11927:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11928:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11929:                
1.186     brouard  11930:     /* Other stuffs, more or less useful */    
1.254     brouard  11931:     while(fgets(line, MAXLINE, ficpar)) {
                   11932:       /* If line starts with a # it is a comment */
                   11933:       if (line[0] == '#') {
                   11934:        numlinepar++;
                   11935:        fputs(line,stdout);
                   11936:        fputs(line,ficparo);
                   11937:        fputs(line,ficlog);
                   11938:        continue;
                   11939:       }else
                   11940:        break;
                   11941:     }
                   11942: 
                   11943:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11944:       
                   11945:       if (num_filled != 7) {
                   11946:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11947:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11948:        goto end;
                   11949:       }
                   11950:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11951:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11952:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11953:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11954:     }
1.254     brouard  11955: 
                   11956:     while(fgets(line, MAXLINE, ficpar)) {
                   11957:       /* If line starts with a # it is a comment */
                   11958:       if (line[0] == '#') {
                   11959:        numlinepar++;
                   11960:        fputs(line,stdout);
                   11961:        fputs(line,ficparo);
                   11962:        fputs(line,ficlog);
                   11963:        continue;
                   11964:       }else
                   11965:        break;
1.126     brouard  11966:     }
                   11967:     
                   11968:     
                   11969:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11970:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11971:     
1.254     brouard  11972:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11973:       if (num_filled != 1) {
                   11974:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11975:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11976:        goto end;
                   11977:       }
                   11978:       printf("pop_based=%d\n",popbased);
                   11979:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11980:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11981:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11982:     }
                   11983:      
1.258     brouard  11984:     /* Results */
                   11985:     nresult=0;
                   11986:     do{
                   11987:       if(!fgets(line, MAXLINE, ficpar)){
                   11988:        endishere=1;
                   11989:        parameterline=14;
                   11990:       }else if (line[0] == '#') {
                   11991:        /* If line starts with a # it is a comment */
1.254     brouard  11992:        numlinepar++;
                   11993:        fputs(line,stdout);
                   11994:        fputs(line,ficparo);
                   11995:        fputs(line,ficlog);
                   11996:        continue;
1.258     brouard  11997:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11998:        parameterline=11;
                   11999:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12000:        parameterline=12;
                   12001:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12002:        parameterline=13;
                   12003:       else{
                   12004:        parameterline=14;
1.254     brouard  12005:       }
1.258     brouard  12006:       switch (parameterline){ 
                   12007:       case 11:
                   12008:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12009:          if (num_filled != 8) {
                   12010:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12011:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12012:            goto end;
                   12013:          }
                   12014:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12015:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12016:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12017:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12018:          /* day and month of proj2 are not used but only year anproj2.*/
                   12019:        }
1.254     brouard  12020:        break;
1.258     brouard  12021:       case 12:
                   12022:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12023:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12024:          if (num_filled != 8) {
1.262     brouard  12025:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12026:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12027:            goto end;
                   12028:          }
                   12029:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12030:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12031:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12032:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12033:          /* day and month of proj2 are not used but only year anproj2.*/
                   12034:        }
1.230     brouard  12035:        break;
1.258     brouard  12036:       case 13:
                   12037:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12038:          if (num_filled == 0){
                   12039:            resultline[0]='\0';
                   12040:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12041:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12042:            break;
                   12043:          } else if (num_filled != 1){
                   12044:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12045:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12046:          }
                   12047:          nresult++; /* Sum of resultlines */
                   12048:          printf("Result %d: result=%s\n",nresult, resultline);
                   12049:          if(nresult > MAXRESULTLINES){
                   12050:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12051:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12052:            goto end;
                   12053:          }
                   12054:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12055:          fprintf(ficparo,"result: %s\n",resultline);
                   12056:          fprintf(ficres,"result: %s\n",resultline);
                   12057:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12058:          break;
1.258     brouard  12059:        case 14: 
1.259     brouard  12060:          if(ncovmodel >2 && nresult==0 ){
                   12061:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12062:            goto end;
                   12063:          }
1.259     brouard  12064:          break;
1.258     brouard  12065:        default:
                   12066:          nresult=1;
                   12067:          decoderesult(".",nresult ); /* No covariate */
                   12068:        }
                   12069:       } /* End switch parameterline */
                   12070:     }while(endishere==0); /* End do */
1.126     brouard  12071:     
1.230     brouard  12072:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12073:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12074:     
                   12075:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12076:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12077:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12078: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12079: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12080:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12081: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12082: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12083:     }else{
1.270   ! brouard  12084:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
        !          12085:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12086:     }
                   12087:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12088:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  12089:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  12090:                
1.225     brouard  12091:     /*------------ free_vector  -------------*/
                   12092:     /*  chdir(path); */
1.220     brouard  12093:                
1.215     brouard  12094:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12095:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12096:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12097:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12098:     free_lvector(num,1,n);
                   12099:     free_vector(agedc,1,n);
                   12100:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12101:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12102:     fclose(ficparo);
                   12103:     fclose(ficres);
1.220     brouard  12104:                
                   12105:                
1.186     brouard  12106:     /* Other results (useful)*/
1.220     brouard  12107:                
                   12108:                
1.126     brouard  12109:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12110:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12111:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12112:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12113:     fclose(ficrespl);
                   12114: 
                   12115:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12116:     /*#include "hpijx.h"*/
                   12117:     hPijx(p, bage, fage);
1.145     brouard  12118:     fclose(ficrespij);
1.227     brouard  12119:     
1.220     brouard  12120:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12121:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12122:     k=1;
1.126     brouard  12123:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12124:     
1.269     brouard  12125:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12126:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12127:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12128:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12129:        for(k=1;k<=ncovcombmax;k++)
                   12130:          probs[i][j][k]=0.;
1.269     brouard  12131:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12132:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12133:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12134:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12135:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12136:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12137:          for(k=1;k<=ncovcombmax;k++)
                   12138:            mobaverages[i][j][k]=0.;
1.219     brouard  12139:       mobaverage=mobaverages;
                   12140:       if (mobilav!=0) {
1.235     brouard  12141:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12142:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12143:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12144:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12145:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12146:        }
1.269     brouard  12147:       } else if (mobilavproj !=0) {
1.235     brouard  12148:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12149:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12150:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12151:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12152:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12153:        }
1.269     brouard  12154:       }else{
                   12155:        printf("Internal error moving average\n");
                   12156:        fflush(stdout);
                   12157:        exit(1);
1.219     brouard  12158:       }
                   12159:     }/* end if moving average */
1.227     brouard  12160:     
1.126     brouard  12161:     /*---------- Forecasting ------------------*/
                   12162:     if(prevfcast==1){
                   12163:       /*    if(stepm ==1){*/
1.269     brouard  12164:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12165:     }
1.269     brouard  12166: 
                   12167:     /* Backcasting */
1.217     brouard  12168:     if(backcast==1){
1.219     brouard  12169:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12170:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12171:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12172: 
                   12173:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12174: 
                   12175:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12176: 
1.219     brouard  12177:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12178:       fclose(ficresplb);
                   12179: 
1.222     brouard  12180:       hBijx(p, bage, fage, mobaverage);
                   12181:       fclose(ficrespijb);
1.219     brouard  12182: 
1.269     brouard  12183:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12184:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12185:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12186: 
                   12187:       
1.269     brouard  12188:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12189:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12190:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12191:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12192:     }    /* end  Backcasting */
1.268     brouard  12193:  
1.186     brouard  12194:  
                   12195:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12196: 
1.215     brouard  12197:     free_ivector(wav,1,imx);
                   12198:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12199:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12200:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12201:                
                   12202:                
1.127     brouard  12203:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12204:                
1.201     brouard  12205:     strcpy(filerese,"E_");
                   12206:     strcat(filerese,fileresu);
1.126     brouard  12207:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12208:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12209:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12210:     }
1.208     brouard  12211:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12212:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12213: 
                   12214:     pstamp(ficreseij);
1.219     brouard  12215:                
1.235     brouard  12216:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12217:     if (cptcovn < 1){i1=1;}
                   12218:     
                   12219:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12220:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12221:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12222:        continue;
1.219     brouard  12223:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12224:       printf("\n#****** ");
1.225     brouard  12225:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12226:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12227:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12228:       }
                   12229:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12230:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12231:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12232:       }
                   12233:       fprintf(ficreseij,"******\n");
1.235     brouard  12234:       printf("******\n");
1.219     brouard  12235:       
                   12236:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12237:       oldm=oldms;savm=savms;
1.235     brouard  12238:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12239:       
1.219     brouard  12240:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12241:     }
                   12242:     fclose(ficreseij);
1.208     brouard  12243:     printf("done evsij\n");fflush(stdout);
                   12244:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12245: 
1.218     brouard  12246:                
1.227     brouard  12247:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12248:                
1.201     brouard  12249:     strcpy(filerest,"T_");
                   12250:     strcat(filerest,fileresu);
1.127     brouard  12251:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12252:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12253:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12254:     }
1.208     brouard  12255:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12256:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12257:     strcpy(fileresstde,"STDE_");
                   12258:     strcat(fileresstde,fileresu);
1.126     brouard  12259:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12260:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12261:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12262:     }
1.227     brouard  12263:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12264:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12265: 
1.201     brouard  12266:     strcpy(filerescve,"CVE_");
                   12267:     strcat(filerescve,fileresu);
1.126     brouard  12268:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12269:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12270:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12271:     }
1.227     brouard  12272:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12273:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12274: 
1.201     brouard  12275:     strcpy(fileresv,"V_");
                   12276:     strcat(fileresv,fileresu);
1.126     brouard  12277:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12278:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12279:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12280:     }
1.227     brouard  12281:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12282:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12283: 
1.235     brouard  12284:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12285:     if (cptcovn < 1){i1=1;}
                   12286:     
                   12287:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12288:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12289:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12290:        continue;
1.242     brouard  12291:       printf("\n#****** Result for:");
                   12292:       fprintf(ficrest,"\n#****** Result for:");
                   12293:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12294:       for(j=1;j<=cptcoveff;j++){ 
                   12295:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12296:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12297:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12298:       }
1.235     brouard  12299:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12300:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12301:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12302:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12303:       }        
1.208     brouard  12304:       fprintf(ficrest,"******\n");
1.227     brouard  12305:       fprintf(ficlog,"******\n");
                   12306:       printf("******\n");
1.208     brouard  12307:       
                   12308:       fprintf(ficresstdeij,"\n#****** ");
                   12309:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12310:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12311:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12312:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12313:       }
1.235     brouard  12314:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12315:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12316:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12317:       }        
1.208     brouard  12318:       fprintf(ficresstdeij,"******\n");
                   12319:       fprintf(ficrescveij,"******\n");
                   12320:       
                   12321:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12322:       /* pstamp(ficresvij); */
1.225     brouard  12323:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12324:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12325:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12326:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12327:       }        
1.208     brouard  12328:       fprintf(ficresvij,"******\n");
                   12329:       
                   12330:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12331:       oldm=oldms;savm=savms;
1.235     brouard  12332:       printf(" cvevsij ");
                   12333:       fprintf(ficlog, " cvevsij ");
                   12334:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12335:       printf(" end cvevsij \n ");
                   12336:       fprintf(ficlog, " end cvevsij \n ");
                   12337:       
                   12338:       /*
                   12339:        */
                   12340:       /* goto endfree; */
                   12341:       
                   12342:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12343:       pstamp(ficrest);
                   12344:       
1.269     brouard  12345:       epj=vector(1,nlstate+1);
1.208     brouard  12346:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12347:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12348:        cptcod= 0; /* To be deleted */
                   12349:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12350:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12351:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12352:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12353:        if(vpopbased==1)
                   12354:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12355:        else
                   12356:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12357:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12358:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12359:        fprintf(ficrest,"\n");
                   12360:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12361:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12362:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12363:        for(age=bage; age <=fage ;age++){
1.235     brouard  12364:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12365:          if (vpopbased==1) {
                   12366:            if(mobilav ==0){
                   12367:              for(i=1; i<=nlstate;i++)
                   12368:                prlim[i][i]=probs[(int)age][i][k];
                   12369:            }else{ /* mobilav */ 
                   12370:              for(i=1; i<=nlstate;i++)
                   12371:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12372:            }
                   12373:          }
1.219     brouard  12374:          
1.227     brouard  12375:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12376:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12377:          /* printf(" age %4.0f ",age); */
                   12378:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12379:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12380:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12381:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12382:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12383:            }
                   12384:            epj[nlstate+1] +=epj[j];
                   12385:          }
                   12386:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12387:          
1.227     brouard  12388:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12389:            for(j=1;j <=nlstate;j++)
                   12390:              vepp += vareij[i][j][(int)age];
                   12391:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12392:          for(j=1;j <=nlstate;j++){
                   12393:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12394:          }
                   12395:          fprintf(ficrest,"\n");
                   12396:        }
1.208     brouard  12397:       } /* End vpopbased */
1.269     brouard  12398:       free_vector(epj,1,nlstate+1);
1.208     brouard  12399:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12400:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12401:       printf("done selection\n");fflush(stdout);
                   12402:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12403:       
1.235     brouard  12404:     } /* End k selection */
1.227     brouard  12405: 
                   12406:     printf("done State-specific expectancies\n");fflush(stdout);
                   12407:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12408: 
1.269     brouard  12409:     /* variance-covariance of period prevalence*/
                   12410:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12411: 
1.227     brouard  12412:     
                   12413:     free_vector(weight,1,n);
                   12414:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12415:     free_imatrix(s,1,maxwav+1,1,n);
                   12416:     free_matrix(anint,1,maxwav,1,n); 
                   12417:     free_matrix(mint,1,maxwav,1,n);
                   12418:     free_ivector(cod,1,n);
                   12419:     free_ivector(tab,1,NCOVMAX);
                   12420:     fclose(ficresstdeij);
                   12421:     fclose(ficrescveij);
                   12422:     fclose(ficresvij);
                   12423:     fclose(ficrest);
                   12424:     fclose(ficpar);
                   12425:     
                   12426:     
1.126     brouard  12427:     /*---------- End : free ----------------*/
1.219     brouard  12428:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12429:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12430:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12431:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12432:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12433:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12434:   /* endfree:*/
                   12435:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12436:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12437:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12438:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12439:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12440:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12441:   free_matrix(covar,0,NCOVMAX,1,n);
                   12442:   free_matrix(matcov,1,npar,1,npar);
                   12443:   free_matrix(hess,1,npar,1,npar);
                   12444:   /*free_vector(delti,1,npar);*/
                   12445:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12446:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12447:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12448:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12449:   
                   12450:   free_ivector(ncodemax,1,NCOVMAX);
                   12451:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12452:   free_ivector(Dummy,-1,NCOVMAX);
                   12453:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12454:   free_ivector(DummyV,1,NCOVMAX);
                   12455:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12456:   free_ivector(Typevar,-1,NCOVMAX);
                   12457:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12458:   free_ivector(TvarsQ,1,NCOVMAX);
                   12459:   free_ivector(TvarsQind,1,NCOVMAX);
                   12460:   free_ivector(TvarsD,1,NCOVMAX);
                   12461:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12462:   free_ivector(TvarFD,1,NCOVMAX);
                   12463:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12464:   free_ivector(TvarF,1,NCOVMAX);
                   12465:   free_ivector(TvarFind,1,NCOVMAX);
                   12466:   free_ivector(TvarV,1,NCOVMAX);
                   12467:   free_ivector(TvarVind,1,NCOVMAX);
                   12468:   free_ivector(TvarA,1,NCOVMAX);
                   12469:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12470:   free_ivector(TvarFQ,1,NCOVMAX);
                   12471:   free_ivector(TvarFQind,1,NCOVMAX);
                   12472:   free_ivector(TvarVD,1,NCOVMAX);
                   12473:   free_ivector(TvarVDind,1,NCOVMAX);
                   12474:   free_ivector(TvarVQ,1,NCOVMAX);
                   12475:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12476:   free_ivector(Tvarsel,1,NCOVMAX);
                   12477:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12478:   free_ivector(Tposprod,1,NCOVMAX);
                   12479:   free_ivector(Tprod,1,NCOVMAX);
                   12480:   free_ivector(Tvaraff,1,NCOVMAX);
                   12481:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12482:   free_ivector(Tage,1,NCOVMAX);
                   12483:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12484:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12485:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12486:   
                   12487:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12488:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12489:   fflush(fichtm);
                   12490:   fflush(ficgp);
                   12491:   
1.227     brouard  12492:   
1.126     brouard  12493:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12494:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12495:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12496:   }else{
                   12497:     printf("End of Imach\n");
                   12498:     fprintf(ficlog,"End of Imach\n");
                   12499:   }
                   12500:   printf("See log file on %s\n",filelog);
                   12501:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12502:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12503:   rend_time = time(NULL);  
                   12504:   end_time = *localtime(&rend_time);
                   12505:   /* tml = *localtime(&end_time.tm_sec); */
                   12506:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12507:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12508:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12509:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12510:   
1.157     brouard  12511:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12512:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12513:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12514:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12515: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12516:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12517:   fclose(fichtm);
                   12518:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12519:   fclose(fichtmcov);
                   12520:   fclose(ficgp);
                   12521:   fclose(ficlog);
                   12522:   /*------ End -----------*/
1.227     brouard  12523:   
                   12524:   
                   12525:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12526: #ifdef WIN32
1.227     brouard  12527:   if (_chdir(pathcd) != 0)
                   12528:     printf("Can't move to directory %s!\n",path);
                   12529:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12530: #else
1.227     brouard  12531:     if(chdir(pathcd) != 0)
                   12532:       printf("Can't move to directory %s!\n", path);
                   12533:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12534: #endif 
1.126     brouard  12535:     printf("Current directory %s!\n",pathcd);
                   12536:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12537:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12538: #ifdef _WIN32
1.126     brouard  12539:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12540: #endif
                   12541:   if(!stat(plotcmd,&info)){
1.158     brouard  12542:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12543:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12544:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12545:     }else
                   12546:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12547: #ifdef __unix
1.126     brouard  12548:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12549:     if(!stat(plotcmd,&info)){
1.158     brouard  12550:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12551:     }else
                   12552:       strcpy(pplotcmd,plotcmd);
                   12553: #endif
                   12554:   }else
                   12555:     strcpy(pplotcmd,plotcmd);
                   12556:   
                   12557:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12558:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12559:   
1.126     brouard  12560:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12561:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12562:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12563:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12564:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12565:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12566:   }
1.158     brouard  12567:   printf(" Successful, please wait...");
1.126     brouard  12568:   while (z[0] != 'q') {
                   12569:     /* chdir(path); */
1.154     brouard  12570:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12571:     scanf("%s",z);
                   12572: /*     if (z[0] == 'c') system("./imach"); */
                   12573:     if (z[0] == 'e') {
1.158     brouard  12574: #ifdef __APPLE__
1.152     brouard  12575:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12576: #elif __linux
                   12577:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12578: #else
1.152     brouard  12579:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12580: #endif
                   12581:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12582:       system(pplotcmd);
1.126     brouard  12583:     }
                   12584:     else if (z[0] == 'g') system(plotcmd);
                   12585:     else if (z[0] == 'q') exit(0);
                   12586:   }
1.227     brouard  12587: end:
1.126     brouard  12588:   while (z[0] != 'q') {
1.195     brouard  12589:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12590:     scanf("%s",z);
                   12591:   }
                   12592: }

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