Annotation of imach/src/imach.c, revision 1.271

1.271   ! brouard     1: /* $Id: imach.c,v 1.270 2017/05/24 05:45:29 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.271   ! brouard     4:   Revision 1.270  2017/05/24 05:45:29  brouard
        !             5:   *** empty log message ***
        !             6: 
1.270     brouard     7:   Revision 1.269  2017/05/23 08:39:25  brouard
                      8:   Summary: Code into subroutine, cleanings
                      9: 
1.269     brouard    10:   Revision 1.268  2017/05/18 20:09:32  brouard
                     11:   Summary: backprojection and confidence intervals of backprevalence
                     12: 
1.268     brouard    13:   Revision 1.267  2017/05/13 10:25:05  brouard
                     14:   Summary: temporary save for backprojection
                     15: 
1.267     brouard    16:   Revision 1.266  2017/05/13 07:26:12  brouard
                     17:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     18: 
1.266     brouard    19:   Revision 1.265  2017/04/26 16:22:11  brouard
                     20:   Summary: imach 0.99r13 Some bugs fixed
                     21: 
1.265     brouard    22:   Revision 1.264  2017/04/26 06:01:29  brouard
                     23:   Summary: Labels in graphs
                     24: 
1.264     brouard    25:   Revision 1.263  2017/04/24 15:23:15  brouard
                     26:   Summary: to save
                     27: 
1.263     brouard    28:   Revision 1.262  2017/04/18 16:48:12  brouard
                     29:   *** empty log message ***
                     30: 
1.262     brouard    31:   Revision 1.261  2017/04/05 10:14:09  brouard
                     32:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     33: 
1.261     brouard    34:   Revision 1.260  2017/04/04 17:46:59  brouard
                     35:   Summary: Gnuplot indexations fixed (humm)
                     36: 
1.260     brouard    37:   Revision 1.259  2017/04/04 13:01:16  brouard
                     38:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     39: 
1.259     brouard    40:   Revision 1.258  2017/04/03 10:17:47  brouard
                     41:   Summary: Version 0.99r12
                     42: 
                     43:   Some cleanings, conformed with updated documentation.
                     44: 
1.258     brouard    45:   Revision 1.257  2017/03/29 16:53:30  brouard
                     46:   Summary: Temp
                     47: 
1.257     brouard    48:   Revision 1.256  2017/03/27 05:50:23  brouard
                     49:   Summary: Temporary
                     50: 
1.256     brouard    51:   Revision 1.255  2017/03/08 16:02:28  brouard
                     52:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     53: 
1.255     brouard    54:   Revision 1.254  2017/03/08 07:13:00  brouard
                     55:   Summary: Fixing data parameter line
                     56: 
1.254     brouard    57:   Revision 1.253  2016/12/15 11:59:41  brouard
                     58:   Summary: 0.99 in progress
                     59: 
1.253     brouard    60:   Revision 1.252  2016/09/15 21:15:37  brouard
                     61:   *** empty log message ***
                     62: 
1.252     brouard    63:   Revision 1.251  2016/09/15 15:01:13  brouard
                     64:   Summary: not working
                     65: 
1.251     brouard    66:   Revision 1.250  2016/09/08 16:07:27  brouard
                     67:   Summary: continue
                     68: 
1.250     brouard    69:   Revision 1.249  2016/09/07 17:14:18  brouard
                     70:   Summary: Starting values from frequencies
                     71: 
1.249     brouard    72:   Revision 1.248  2016/09/07 14:10:18  brouard
                     73:   *** empty log message ***
                     74: 
1.248     brouard    75:   Revision 1.247  2016/09/02 11:11:21  brouard
                     76:   *** empty log message ***
                     77: 
1.247     brouard    78:   Revision 1.246  2016/09/02 08:49:22  brouard
                     79:   *** empty log message ***
                     80: 
1.246     brouard    81:   Revision 1.245  2016/09/02 07:25:01  brouard
                     82:   *** empty log message ***
                     83: 
1.245     brouard    84:   Revision 1.244  2016/09/02 07:17:34  brouard
                     85:   *** empty log message ***
                     86: 
1.244     brouard    87:   Revision 1.243  2016/09/02 06:45:35  brouard
                     88:   *** empty log message ***
                     89: 
1.243     brouard    90:   Revision 1.242  2016/08/30 15:01:20  brouard
                     91:   Summary: Fixing a lots
                     92: 
1.242     brouard    93:   Revision 1.241  2016/08/29 17:17:25  brouard
                     94:   Summary: gnuplot problem in Back projection to fix
                     95: 
1.241     brouard    96:   Revision 1.240  2016/08/29 07:53:18  brouard
                     97:   Summary: Better
                     98: 
1.240     brouard    99:   Revision 1.239  2016/08/26 15:51:03  brouard
                    100:   Summary: Improvement in Powell output in order to copy and paste
                    101: 
                    102:   Author:
                    103: 
1.239     brouard   104:   Revision 1.238  2016/08/26 14:23:35  brouard
                    105:   Summary: Starting tests of 0.99
                    106: 
1.238     brouard   107:   Revision 1.237  2016/08/26 09:20:19  brouard
                    108:   Summary: to valgrind
                    109: 
1.237     brouard   110:   Revision 1.236  2016/08/25 10:50:18  brouard
                    111:   *** empty log message ***
                    112: 
1.236     brouard   113:   Revision 1.235  2016/08/25 06:59:23  brouard
                    114:   *** empty log message ***
                    115: 
1.235     brouard   116:   Revision 1.234  2016/08/23 16:51:20  brouard
                    117:   *** empty log message ***
                    118: 
1.234     brouard   119:   Revision 1.233  2016/08/23 07:40:50  brouard
                    120:   Summary: not working
                    121: 
1.233     brouard   122:   Revision 1.232  2016/08/22 14:20:21  brouard
                    123:   Summary: not working
                    124: 
1.232     brouard   125:   Revision 1.231  2016/08/22 07:17:15  brouard
                    126:   Summary: not working
                    127: 
1.231     brouard   128:   Revision 1.230  2016/08/22 06:55:53  brouard
                    129:   Summary: Not working
                    130: 
1.230     brouard   131:   Revision 1.229  2016/07/23 09:45:53  brouard
                    132:   Summary: Completing for func too
                    133: 
1.229     brouard   134:   Revision 1.228  2016/07/22 17:45:30  brouard
                    135:   Summary: Fixing some arrays, still debugging
                    136: 
1.227     brouard   137:   Revision 1.226  2016/07/12 18:42:34  brouard
                    138:   Summary: temp
                    139: 
1.226     brouard   140:   Revision 1.225  2016/07/12 08:40:03  brouard
                    141:   Summary: saving but not running
                    142: 
1.225     brouard   143:   Revision 1.224  2016/07/01 13:16:01  brouard
                    144:   Summary: Fixes
                    145: 
1.224     brouard   146:   Revision 1.223  2016/02/19 09:23:35  brouard
                    147:   Summary: temporary
                    148: 
1.223     brouard   149:   Revision 1.222  2016/02/17 08:14:50  brouard
                    150:   Summary: Probably last 0.98 stable version 0.98r6
                    151: 
1.222     brouard   152:   Revision 1.221  2016/02/15 23:35:36  brouard
                    153:   Summary: minor bug
                    154: 
1.220     brouard   155:   Revision 1.219  2016/02/15 00:48:12  brouard
                    156:   *** empty log message ***
                    157: 
1.219     brouard   158:   Revision 1.218  2016/02/12 11:29:23  brouard
                    159:   Summary: 0.99 Back projections
                    160: 
1.218     brouard   161:   Revision 1.217  2015/12/23 17:18:31  brouard
                    162:   Summary: Experimental backcast
                    163: 
1.217     brouard   164:   Revision 1.216  2015/12/18 17:32:11  brouard
                    165:   Summary: 0.98r4 Warning and status=-2
                    166: 
                    167:   Version 0.98r4 is now:
                    168:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    169:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    170:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    171: 
1.216     brouard   172:   Revision 1.215  2015/12/16 08:52:24  brouard
                    173:   Summary: 0.98r4 working
                    174: 
1.215     brouard   175:   Revision 1.214  2015/12/16 06:57:54  brouard
                    176:   Summary: temporary not working
                    177: 
1.214     brouard   178:   Revision 1.213  2015/12/11 18:22:17  brouard
                    179:   Summary: 0.98r4
                    180: 
1.213     brouard   181:   Revision 1.212  2015/11/21 12:47:24  brouard
                    182:   Summary: minor typo
                    183: 
1.212     brouard   184:   Revision 1.211  2015/11/21 12:41:11  brouard
                    185:   Summary: 0.98r3 with some graph of projected cross-sectional
                    186: 
                    187:   Author: Nicolas Brouard
                    188: 
1.211     brouard   189:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   190:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   191:   Summary: Adding ftolpl parameter
                    192:   Author: N Brouard
                    193: 
                    194:   We had difficulties to get smoothed confidence intervals. It was due
                    195:   to the period prevalence which wasn't computed accurately. The inner
                    196:   parameter ftolpl is now an outer parameter of the .imach parameter
                    197:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    198:   computation are long.
                    199: 
1.209     brouard   200:   Revision 1.208  2015/11/17 14:31:57  brouard
                    201:   Summary: temporary
                    202: 
1.208     brouard   203:   Revision 1.207  2015/10/27 17:36:57  brouard
                    204:   *** empty log message ***
                    205: 
1.207     brouard   206:   Revision 1.206  2015/10/24 07:14:11  brouard
                    207:   *** empty log message ***
                    208: 
1.206     brouard   209:   Revision 1.205  2015/10/23 15:50:53  brouard
                    210:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    211: 
1.205     brouard   212:   Revision 1.204  2015/10/01 16:20:26  brouard
                    213:   Summary: Some new graphs of contribution to likelihood
                    214: 
1.204     brouard   215:   Revision 1.203  2015/09/30 17:45:14  brouard
                    216:   Summary: looking at better estimation of the hessian
                    217: 
                    218:   Also a better criteria for convergence to the period prevalence And
                    219:   therefore adding the number of years needed to converge. (The
                    220:   prevalence in any alive state shold sum to one
                    221: 
1.203     brouard   222:   Revision 1.202  2015/09/22 19:45:16  brouard
                    223:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    224: 
1.202     brouard   225:   Revision 1.201  2015/09/15 17:34:58  brouard
                    226:   Summary: 0.98r0
                    227: 
                    228:   - Some new graphs like suvival functions
                    229:   - Some bugs fixed like model=1+age+V2.
                    230: 
1.201     brouard   231:   Revision 1.200  2015/09/09 16:53:55  brouard
                    232:   Summary: Big bug thanks to Flavia
                    233: 
                    234:   Even model=1+age+V2. did not work anymore
                    235: 
1.200     brouard   236:   Revision 1.199  2015/09/07 14:09:23  brouard
                    237:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    238: 
1.199     brouard   239:   Revision 1.198  2015/09/03 07:14:39  brouard
                    240:   Summary: 0.98q5 Flavia
                    241: 
1.198     brouard   242:   Revision 1.197  2015/09/01 18:24:39  brouard
                    243:   *** empty log message ***
                    244: 
1.197     brouard   245:   Revision 1.196  2015/08/18 23:17:52  brouard
                    246:   Summary: 0.98q5
                    247: 
1.196     brouard   248:   Revision 1.195  2015/08/18 16:28:39  brouard
                    249:   Summary: Adding a hack for testing purpose
                    250: 
                    251:   After reading the title, ftol and model lines, if the comment line has
                    252:   a q, starting with #q, the answer at the end of the run is quit. It
                    253:   permits to run test files in batch with ctest. The former workaround was
                    254:   $ echo q | imach foo.imach
                    255: 
1.195     brouard   256:   Revision 1.194  2015/08/18 13:32:00  brouard
                    257:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    258: 
1.194     brouard   259:   Revision 1.193  2015/08/04 07:17:42  brouard
                    260:   Summary: 0.98q4
                    261: 
1.193     brouard   262:   Revision 1.192  2015/07/16 16:49:02  brouard
                    263:   Summary: Fixing some outputs
                    264: 
1.192     brouard   265:   Revision 1.191  2015/07/14 10:00:33  brouard
                    266:   Summary: Some fixes
                    267: 
1.191     brouard   268:   Revision 1.190  2015/05/05 08:51:13  brouard
                    269:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    270: 
                    271:   Fix 1+age+.
                    272: 
1.190     brouard   273:   Revision 1.189  2015/04/30 14:45:16  brouard
                    274:   Summary: 0.98q2
                    275: 
1.189     brouard   276:   Revision 1.188  2015/04/30 08:27:53  brouard
                    277:   *** empty log message ***
                    278: 
1.188     brouard   279:   Revision 1.187  2015/04/29 09:11:15  brouard
                    280:   *** empty log message ***
                    281: 
1.187     brouard   282:   Revision 1.186  2015/04/23 12:01:52  brouard
                    283:   Summary: V1*age is working now, version 0.98q1
                    284: 
                    285:   Some codes had been disabled in order to simplify and Vn*age was
                    286:   working in the optimization phase, ie, giving correct MLE parameters,
                    287:   but, as usual, outputs were not correct and program core dumped.
                    288: 
1.186     brouard   289:   Revision 1.185  2015/03/11 13:26:42  brouard
                    290:   Summary: Inclusion of compile and links command line for Intel Compiler
                    291: 
1.185     brouard   292:   Revision 1.184  2015/03/11 11:52:39  brouard
                    293:   Summary: Back from Windows 8. Intel Compiler
                    294: 
1.184     brouard   295:   Revision 1.183  2015/03/10 20:34:32  brouard
                    296:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    297: 
                    298:   We use directest instead of original Powell test; probably no
                    299:   incidence on the results, but better justifications;
                    300:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    301:   wrong results.
                    302: 
1.183     brouard   303:   Revision 1.182  2015/02/12 08:19:57  brouard
                    304:   Summary: Trying to keep directest which seems simpler and more general
                    305:   Author: Nicolas Brouard
                    306: 
1.182     brouard   307:   Revision 1.181  2015/02/11 23:22:24  brouard
                    308:   Summary: Comments on Powell added
                    309: 
                    310:   Author:
                    311: 
1.181     brouard   312:   Revision 1.180  2015/02/11 17:33:45  brouard
                    313:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    314: 
1.180     brouard   315:   Revision 1.179  2015/01/04 09:57:06  brouard
                    316:   Summary: back to OS/X
                    317: 
1.179     brouard   318:   Revision 1.178  2015/01/04 09:35:48  brouard
                    319:   *** empty log message ***
                    320: 
1.178     brouard   321:   Revision 1.177  2015/01/03 18:40:56  brouard
                    322:   Summary: Still testing ilc32 on OSX
                    323: 
1.177     brouard   324:   Revision 1.176  2015/01/03 16:45:04  brouard
                    325:   *** empty log message ***
                    326: 
1.176     brouard   327:   Revision 1.175  2015/01/03 16:33:42  brouard
                    328:   *** empty log message ***
                    329: 
1.175     brouard   330:   Revision 1.174  2015/01/03 16:15:49  brouard
                    331:   Summary: Still in cross-compilation
                    332: 
1.174     brouard   333:   Revision 1.173  2015/01/03 12:06:26  brouard
                    334:   Summary: trying to detect cross-compilation
                    335: 
1.173     brouard   336:   Revision 1.172  2014/12/27 12:07:47  brouard
                    337:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    338: 
1.172     brouard   339:   Revision 1.171  2014/12/23 13:26:59  brouard
                    340:   Summary: Back from Visual C
                    341: 
                    342:   Still problem with utsname.h on Windows
                    343: 
1.171     brouard   344:   Revision 1.170  2014/12/23 11:17:12  brouard
                    345:   Summary: Cleaning some \%% back to %%
                    346: 
                    347:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    348: 
1.170     brouard   349:   Revision 1.169  2014/12/22 23:08:31  brouard
                    350:   Summary: 0.98p
                    351: 
                    352:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    353: 
1.169     brouard   354:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   355:   Summary: update
1.169     brouard   356: 
1.168     brouard   357:   Revision 1.167  2014/12/22 13:50:56  brouard
                    358:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    359: 
                    360:   Testing on Linux 64
                    361: 
1.167     brouard   362:   Revision 1.166  2014/12/22 11:40:47  brouard
                    363:   *** empty log message ***
                    364: 
1.166     brouard   365:   Revision 1.165  2014/12/16 11:20:36  brouard
                    366:   Summary: After compiling on Visual C
                    367: 
                    368:   * imach.c (Module): Merging 1.61 to 1.162
                    369: 
1.165     brouard   370:   Revision 1.164  2014/12/16 10:52:11  brouard
                    371:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    372: 
                    373:   * imach.c (Module): Merging 1.61 to 1.162
                    374: 
1.164     brouard   375:   Revision 1.163  2014/12/16 10:30:11  brouard
                    376:   * imach.c (Module): Merging 1.61 to 1.162
                    377: 
1.163     brouard   378:   Revision 1.162  2014/09/25 11:43:39  brouard
                    379:   Summary: temporary backup 0.99!
                    380: 
1.162     brouard   381:   Revision 1.1  2014/09/16 11:06:58  brouard
                    382:   Summary: With some code (wrong) for nlopt
                    383: 
                    384:   Author:
                    385: 
                    386:   Revision 1.161  2014/09/15 20:41:41  brouard
                    387:   Summary: Problem with macro SQR on Intel compiler
                    388: 
1.161     brouard   389:   Revision 1.160  2014/09/02 09:24:05  brouard
                    390:   *** empty log message ***
                    391: 
1.160     brouard   392:   Revision 1.159  2014/09/01 10:34:10  brouard
                    393:   Summary: WIN32
                    394:   Author: Brouard
                    395: 
1.159     brouard   396:   Revision 1.158  2014/08/27 17:11:51  brouard
                    397:   *** empty log message ***
                    398: 
1.158     brouard   399:   Revision 1.157  2014/08/27 16:26:55  brouard
                    400:   Summary: Preparing windows Visual studio version
                    401:   Author: Brouard
                    402: 
                    403:   In order to compile on Visual studio, time.h is now correct and time_t
                    404:   and tm struct should be used. difftime should be used but sometimes I
                    405:   just make the differences in raw time format (time(&now).
                    406:   Trying to suppress #ifdef LINUX
                    407:   Add xdg-open for __linux in order to open default browser.
                    408: 
1.157     brouard   409:   Revision 1.156  2014/08/25 20:10:10  brouard
                    410:   *** empty log message ***
                    411: 
1.156     brouard   412:   Revision 1.155  2014/08/25 18:32:34  brouard
                    413:   Summary: New compile, minor changes
                    414:   Author: Brouard
                    415: 
1.155     brouard   416:   Revision 1.154  2014/06/20 17:32:08  brouard
                    417:   Summary: Outputs now all graphs of convergence to period prevalence
                    418: 
1.154     brouard   419:   Revision 1.153  2014/06/20 16:45:46  brouard
                    420:   Summary: If 3 live state, convergence to period prevalence on same graph
                    421:   Author: Brouard
                    422: 
1.153     brouard   423:   Revision 1.152  2014/06/18 17:54:09  brouard
                    424:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    425: 
1.152     brouard   426:   Revision 1.151  2014/06/18 16:43:30  brouard
                    427:   *** empty log message ***
                    428: 
1.151     brouard   429:   Revision 1.150  2014/06/18 16:42:35  brouard
                    430:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    431:   Author: brouard
                    432: 
1.150     brouard   433:   Revision 1.149  2014/06/18 15:51:14  brouard
                    434:   Summary: Some fixes in parameter files errors
                    435:   Author: Nicolas Brouard
                    436: 
1.149     brouard   437:   Revision 1.148  2014/06/17 17:38:48  brouard
                    438:   Summary: Nothing new
                    439:   Author: Brouard
                    440: 
                    441:   Just a new packaging for OS/X version 0.98nS
                    442: 
1.148     brouard   443:   Revision 1.147  2014/06/16 10:33:11  brouard
                    444:   *** empty log message ***
                    445: 
1.147     brouard   446:   Revision 1.146  2014/06/16 10:20:28  brouard
                    447:   Summary: Merge
                    448:   Author: Brouard
                    449: 
                    450:   Merge, before building revised version.
                    451: 
1.146     brouard   452:   Revision 1.145  2014/06/10 21:23:15  brouard
                    453:   Summary: Debugging with valgrind
                    454:   Author: Nicolas Brouard
                    455: 
                    456:   Lot of changes in order to output the results with some covariates
                    457:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    458:   improve the code.
                    459:   No more memory valgrind error but a lot has to be done in order to
                    460:   continue the work of splitting the code into subroutines.
                    461:   Also, decodemodel has been improved. Tricode is still not
                    462:   optimal. nbcode should be improved. Documentation has been added in
                    463:   the source code.
                    464: 
1.144     brouard   465:   Revision 1.143  2014/01/26 09:45:38  brouard
                    466:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    467: 
                    468:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    469:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    470: 
1.143     brouard   471:   Revision 1.142  2014/01/26 03:57:36  brouard
                    472:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    473: 
                    474:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    475: 
1.142     brouard   476:   Revision 1.141  2014/01/26 02:42:01  brouard
                    477:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    478: 
1.141     brouard   479:   Revision 1.140  2011/09/02 10:37:54  brouard
                    480:   Summary: times.h is ok with mingw32 now.
                    481: 
1.140     brouard   482:   Revision 1.139  2010/06/14 07:50:17  brouard
                    483:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    484:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    485: 
1.139     brouard   486:   Revision 1.138  2010/04/30 18:19:40  brouard
                    487:   *** empty log message ***
                    488: 
1.138     brouard   489:   Revision 1.137  2010/04/29 18:11:38  brouard
                    490:   (Module): Checking covariates for more complex models
                    491:   than V1+V2. A lot of change to be done. Unstable.
                    492: 
1.137     brouard   493:   Revision 1.136  2010/04/26 20:30:53  brouard
                    494:   (Module): merging some libgsl code. Fixing computation
                    495:   of likelione (using inter/intrapolation if mle = 0) in order to
                    496:   get same likelihood as if mle=1.
                    497:   Some cleaning of code and comments added.
                    498: 
1.136     brouard   499:   Revision 1.135  2009/10/29 15:33:14  brouard
                    500:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    501: 
1.135     brouard   502:   Revision 1.134  2009/10/29 13:18:53  brouard
                    503:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    504: 
1.134     brouard   505:   Revision 1.133  2009/07/06 10:21:25  brouard
                    506:   just nforces
                    507: 
1.133     brouard   508:   Revision 1.132  2009/07/06 08:22:05  brouard
                    509:   Many tings
                    510: 
1.132     brouard   511:   Revision 1.131  2009/06/20 16:22:47  brouard
                    512:   Some dimensions resccaled
                    513: 
1.131     brouard   514:   Revision 1.130  2009/05/26 06:44:34  brouard
                    515:   (Module): Max Covariate is now set to 20 instead of 8. A
                    516:   lot of cleaning with variables initialized to 0. Trying to make
                    517:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    518: 
1.130     brouard   519:   Revision 1.129  2007/08/31 13:49:27  lievre
                    520:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    521: 
1.129     lievre    522:   Revision 1.128  2006/06/30 13:02:05  brouard
                    523:   (Module): Clarifications on computing e.j
                    524: 
1.128     brouard   525:   Revision 1.127  2006/04/28 18:11:50  brouard
                    526:   (Module): Yes the sum of survivors was wrong since
                    527:   imach-114 because nhstepm was no more computed in the age
                    528:   loop. Now we define nhstepma in the age loop.
                    529:   (Module): In order to speed up (in case of numerous covariates) we
                    530:   compute health expectancies (without variances) in a first step
                    531:   and then all the health expectancies with variances or standard
                    532:   deviation (needs data from the Hessian matrices) which slows the
                    533:   computation.
                    534:   In the future we should be able to stop the program is only health
                    535:   expectancies and graph are needed without standard deviations.
                    536: 
1.127     brouard   537:   Revision 1.126  2006/04/28 17:23:28  brouard
                    538:   (Module): Yes the sum of survivors was wrong since
                    539:   imach-114 because nhstepm was no more computed in the age
                    540:   loop. Now we define nhstepma in the age loop.
                    541:   Version 0.98h
                    542: 
1.126     brouard   543:   Revision 1.125  2006/04/04 15:20:31  lievre
                    544:   Errors in calculation of health expectancies. Age was not initialized.
                    545:   Forecasting file added.
                    546: 
                    547:   Revision 1.124  2006/03/22 17:13:53  lievre
                    548:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    549:   The log-likelihood is printed in the log file
                    550: 
                    551:   Revision 1.123  2006/03/20 10:52:43  brouard
                    552:   * imach.c (Module): <title> changed, corresponds to .htm file
                    553:   name. <head> headers where missing.
                    554: 
                    555:   * imach.c (Module): Weights can have a decimal point as for
                    556:   English (a comma might work with a correct LC_NUMERIC environment,
                    557:   otherwise the weight is truncated).
                    558:   Modification of warning when the covariates values are not 0 or
                    559:   1.
                    560:   Version 0.98g
                    561: 
                    562:   Revision 1.122  2006/03/20 09:45:41  brouard
                    563:   (Module): Weights can have a decimal point as for
                    564:   English (a comma might work with a correct LC_NUMERIC environment,
                    565:   otherwise the weight is truncated).
                    566:   Modification of warning when the covariates values are not 0 or
                    567:   1.
                    568:   Version 0.98g
                    569: 
                    570:   Revision 1.121  2006/03/16 17:45:01  lievre
                    571:   * imach.c (Module): Comments concerning covariates added
                    572: 
                    573:   * imach.c (Module): refinements in the computation of lli if
                    574:   status=-2 in order to have more reliable computation if stepm is
                    575:   not 1 month. Version 0.98f
                    576: 
                    577:   Revision 1.120  2006/03/16 15:10:38  lievre
                    578:   (Module): refinements in the computation of lli if
                    579:   status=-2 in order to have more reliable computation if stepm is
                    580:   not 1 month. Version 0.98f
                    581: 
                    582:   Revision 1.119  2006/03/15 17:42:26  brouard
                    583:   (Module): Bug if status = -2, the loglikelihood was
                    584:   computed as likelihood omitting the logarithm. Version O.98e
                    585: 
                    586:   Revision 1.118  2006/03/14 18:20:07  brouard
                    587:   (Module): varevsij Comments added explaining the second
                    588:   table of variances if popbased=1 .
                    589:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    590:   (Module): Function pstamp added
                    591:   (Module): Version 0.98d
                    592: 
                    593:   Revision 1.117  2006/03/14 17:16:22  brouard
                    594:   (Module): varevsij Comments added explaining the second
                    595:   table of variances if popbased=1 .
                    596:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    597:   (Module): Function pstamp added
                    598:   (Module): Version 0.98d
                    599: 
                    600:   Revision 1.116  2006/03/06 10:29:27  brouard
                    601:   (Module): Variance-covariance wrong links and
                    602:   varian-covariance of ej. is needed (Saito).
                    603: 
                    604:   Revision 1.115  2006/02/27 12:17:45  brouard
                    605:   (Module): One freematrix added in mlikeli! 0.98c
                    606: 
                    607:   Revision 1.114  2006/02/26 12:57:58  brouard
                    608:   (Module): Some improvements in processing parameter
                    609:   filename with strsep.
                    610: 
                    611:   Revision 1.113  2006/02/24 14:20:24  brouard
                    612:   (Module): Memory leaks checks with valgrind and:
                    613:   datafile was not closed, some imatrix were not freed and on matrix
                    614:   allocation too.
                    615: 
                    616:   Revision 1.112  2006/01/30 09:55:26  brouard
                    617:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    618: 
                    619:   Revision 1.111  2006/01/25 20:38:18  brouard
                    620:   (Module): Lots of cleaning and bugs added (Gompertz)
                    621:   (Module): Comments can be added in data file. Missing date values
                    622:   can be a simple dot '.'.
                    623: 
                    624:   Revision 1.110  2006/01/25 00:51:50  brouard
                    625:   (Module): Lots of cleaning and bugs added (Gompertz)
                    626: 
                    627:   Revision 1.109  2006/01/24 19:37:15  brouard
                    628:   (Module): Comments (lines starting with a #) are allowed in data.
                    629: 
                    630:   Revision 1.108  2006/01/19 18:05:42  lievre
                    631:   Gnuplot problem appeared...
                    632:   To be fixed
                    633: 
                    634:   Revision 1.107  2006/01/19 16:20:37  brouard
                    635:   Test existence of gnuplot in imach path
                    636: 
                    637:   Revision 1.106  2006/01/19 13:24:36  brouard
                    638:   Some cleaning and links added in html output
                    639: 
                    640:   Revision 1.105  2006/01/05 20:23:19  lievre
                    641:   *** empty log message ***
                    642: 
                    643:   Revision 1.104  2005/09/30 16:11:43  lievre
                    644:   (Module): sump fixed, loop imx fixed, and simplifications.
                    645:   (Module): If the status is missing at the last wave but we know
                    646:   that the person is alive, then we can code his/her status as -2
                    647:   (instead of missing=-1 in earlier versions) and his/her
                    648:   contributions to the likelihood is 1 - Prob of dying from last
                    649:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    650:   the healthy state at last known wave). Version is 0.98
                    651: 
                    652:   Revision 1.103  2005/09/30 15:54:49  lievre
                    653:   (Module): sump fixed, loop imx fixed, and simplifications.
                    654: 
                    655:   Revision 1.102  2004/09/15 17:31:30  brouard
                    656:   Add the possibility to read data file including tab characters.
                    657: 
                    658:   Revision 1.101  2004/09/15 10:38:38  brouard
                    659:   Fix on curr_time
                    660: 
                    661:   Revision 1.100  2004/07/12 18:29:06  brouard
                    662:   Add version for Mac OS X. Just define UNIX in Makefile
                    663: 
                    664:   Revision 1.99  2004/06/05 08:57:40  brouard
                    665:   *** empty log message ***
                    666: 
                    667:   Revision 1.98  2004/05/16 15:05:56  brouard
                    668:   New version 0.97 . First attempt to estimate force of mortality
                    669:   directly from the data i.e. without the need of knowing the health
                    670:   state at each age, but using a Gompertz model: log u =a + b*age .
                    671:   This is the basic analysis of mortality and should be done before any
                    672:   other analysis, in order to test if the mortality estimated from the
                    673:   cross-longitudinal survey is different from the mortality estimated
                    674:   from other sources like vital statistic data.
                    675: 
                    676:   The same imach parameter file can be used but the option for mle should be -3.
                    677: 
1.133     brouard   678:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   679:   former routines in order to include the new code within the former code.
                    680: 
                    681:   The output is very simple: only an estimate of the intercept and of
                    682:   the slope with 95% confident intervals.
                    683: 
                    684:   Current limitations:
                    685:   A) Even if you enter covariates, i.e. with the
                    686:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    687:   B) There is no computation of Life Expectancy nor Life Table.
                    688: 
                    689:   Revision 1.97  2004/02/20 13:25:42  lievre
                    690:   Version 0.96d. Population forecasting command line is (temporarily)
                    691:   suppressed.
                    692: 
                    693:   Revision 1.96  2003/07/15 15:38:55  brouard
                    694:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    695:   rewritten within the same printf. Workaround: many printfs.
                    696: 
                    697:   Revision 1.95  2003/07/08 07:54:34  brouard
                    698:   * imach.c (Repository):
                    699:   (Repository): Using imachwizard code to output a more meaningful covariance
                    700:   matrix (cov(a12,c31) instead of numbers.
                    701: 
                    702:   Revision 1.94  2003/06/27 13:00:02  brouard
                    703:   Just cleaning
                    704: 
                    705:   Revision 1.93  2003/06/25 16:33:55  brouard
                    706:   (Module): On windows (cygwin) function asctime_r doesn't
                    707:   exist so I changed back to asctime which exists.
                    708:   (Module): Version 0.96b
                    709: 
                    710:   Revision 1.92  2003/06/25 16:30:45  brouard
                    711:   (Module): On windows (cygwin) function asctime_r doesn't
                    712:   exist so I changed back to asctime which exists.
                    713: 
                    714:   Revision 1.91  2003/06/25 15:30:29  brouard
                    715:   * imach.c (Repository): Duplicated warning errors corrected.
                    716:   (Repository): Elapsed time after each iteration is now output. It
                    717:   helps to forecast when convergence will be reached. Elapsed time
                    718:   is stamped in powell.  We created a new html file for the graphs
                    719:   concerning matrix of covariance. It has extension -cov.htm.
                    720: 
                    721:   Revision 1.90  2003/06/24 12:34:15  brouard
                    722:   (Module): Some bugs corrected for windows. Also, when
                    723:   mle=-1 a template is output in file "or"mypar.txt with the design
                    724:   of the covariance matrix to be input.
                    725: 
                    726:   Revision 1.89  2003/06/24 12:30:52  brouard
                    727:   (Module): Some bugs corrected for windows. Also, when
                    728:   mle=-1 a template is output in file "or"mypar.txt with the design
                    729:   of the covariance matrix to be input.
                    730: 
                    731:   Revision 1.88  2003/06/23 17:54:56  brouard
                    732:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    733: 
                    734:   Revision 1.87  2003/06/18 12:26:01  brouard
                    735:   Version 0.96
                    736: 
                    737:   Revision 1.86  2003/06/17 20:04:08  brouard
                    738:   (Module): Change position of html and gnuplot routines and added
                    739:   routine fileappend.
                    740: 
                    741:   Revision 1.85  2003/06/17 13:12:43  brouard
                    742:   * imach.c (Repository): Check when date of death was earlier that
                    743:   current date of interview. It may happen when the death was just
                    744:   prior to the death. In this case, dh was negative and likelihood
                    745:   was wrong (infinity). We still send an "Error" but patch by
                    746:   assuming that the date of death was just one stepm after the
                    747:   interview.
                    748:   (Repository): Because some people have very long ID (first column)
                    749:   we changed int to long in num[] and we added a new lvector for
                    750:   memory allocation. But we also truncated to 8 characters (left
                    751:   truncation)
                    752:   (Repository): No more line truncation errors.
                    753: 
                    754:   Revision 1.84  2003/06/13 21:44:43  brouard
                    755:   * imach.c (Repository): Replace "freqsummary" at a correct
                    756:   place. It differs from routine "prevalence" which may be called
                    757:   many times. Probs is memory consuming and must be used with
                    758:   parcimony.
                    759:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    760: 
                    761:   Revision 1.83  2003/06/10 13:39:11  lievre
                    762:   *** empty log message ***
                    763: 
                    764:   Revision 1.82  2003/06/05 15:57:20  brouard
                    765:   Add log in  imach.c and  fullversion number is now printed.
                    766: 
                    767: */
                    768: /*
                    769:    Interpolated Markov Chain
                    770: 
                    771:   Short summary of the programme:
                    772:   
1.227     brouard   773:   This program computes Healthy Life Expectancies or State-specific
                    774:   (if states aren't health statuses) Expectancies from
                    775:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    776: 
                    777:   -1- a first survey ("cross") where individuals from different ages
                    778:   are interviewed on their health status or degree of disability (in
                    779:   the case of a health survey which is our main interest)
                    780: 
                    781:   -2- at least a second wave of interviews ("longitudinal") which
                    782:   measure each change (if any) in individual health status.  Health
                    783:   expectancies are computed from the time spent in each health state
                    784:   according to a model. More health states you consider, more time is
                    785:   necessary to reach the Maximum Likelihood of the parameters involved
                    786:   in the model.  The simplest model is the multinomial logistic model
                    787:   where pij is the probability to be observed in state j at the second
                    788:   wave conditional to be observed in state i at the first
                    789:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    790:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    791:   have a more complex model than "constant and age", you should modify
                    792:   the program where the markup *Covariates have to be included here
                    793:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   794:   convergence.
                    795: 
                    796:   The advantage of this computer programme, compared to a simple
                    797:   multinomial logistic model, is clear when the delay between waves is not
                    798:   identical for each individual. Also, if a individual missed an
                    799:   intermediate interview, the information is lost, but taken into
                    800:   account using an interpolation or extrapolation.  
                    801: 
                    802:   hPijx is the probability to be observed in state i at age x+h
                    803:   conditional to the observed state i at age x. The delay 'h' can be
                    804:   split into an exact number (nh*stepm) of unobserved intermediate
                    805:   states. This elementary transition (by month, quarter,
                    806:   semester or year) is modelled as a multinomial logistic.  The hPx
                    807:   matrix is simply the matrix product of nh*stepm elementary matrices
                    808:   and the contribution of each individual to the likelihood is simply
                    809:   hPijx.
                    810: 
                    811:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   812:   of the life expectancies. It also computes the period (stable) prevalence.
                    813: 
                    814: Back prevalence and projections:
1.227     brouard   815: 
                    816:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    817:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    818:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    819:    mobilavproj)
                    820: 
                    821:     Computes the back prevalence limit for any combination of
                    822:     covariate values k at any age between ageminpar and agemaxpar and
                    823:     returns it in **bprlim. In the loops,
                    824: 
                    825:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    826:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    827: 
                    828:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   829:    Computes for any combination of covariates k and any age between bage and fage 
                    830:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    831:                        oldm=oldms;savm=savms;
1.227     brouard   832: 
1.267     brouard   833:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   834:      Computes the transition matrix starting at age 'age' over
                    835:      'nhstepm*hstepm*stepm' months (i.e. until
                    836:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   837:      nhstepm*hstepm matrices. 
                    838: 
                    839:      Returns p3mat[i][j][h] after calling
                    840:      p3mat[i][j][h]=matprod2(newm,
                    841:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    842:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    843:      oldm);
1.226     brouard   844: 
                    845: Important routines
                    846: 
                    847: - func (or funcone), computes logit (pij) distinguishing
                    848:   o fixed variables (single or product dummies or quantitative);
                    849:   o varying variables by:
                    850:    (1) wave (single, product dummies, quantitative), 
                    851:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    852:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    853:        % varying dummy (not done) or quantitative (not done);
                    854: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    855:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    856: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    857:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    858:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   859: 
1.226     brouard   860: 
                    861:   
1.133     brouard   862:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    863:            Institut national d'études démographiques, Paris.
1.126     brouard   864:   This software have been partly granted by Euro-REVES, a concerted action
                    865:   from the European Union.
                    866:   It is copyrighted identically to a GNU software product, ie programme and
                    867:   software can be distributed freely for non commercial use. Latest version
                    868:   can be accessed at http://euroreves.ined.fr/imach .
                    869: 
                    870:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    871:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    872:   
                    873:   **********************************************************************/
                    874: /*
                    875:   main
                    876:   read parameterfile
                    877:   read datafile
                    878:   concatwav
                    879:   freqsummary
                    880:   if (mle >= 1)
                    881:     mlikeli
                    882:   print results files
                    883:   if mle==1 
                    884:      computes hessian
                    885:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    886:       begin-prev-date,...
                    887:   open gnuplot file
                    888:   open html file
1.145     brouard   889:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    890:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    891:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    892:     freexexit2 possible for memory heap.
                    893: 
                    894:   h Pij x                         | pij_nom  ficrestpij
                    895:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    896:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    897:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    898: 
                    899:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    900:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    901:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    902:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    903:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    904: 
1.126     brouard   905:   forecasting if prevfcast==1 prevforecast call prevalence()
                    906:   health expectancies
                    907:   Variance-covariance of DFLE
                    908:   prevalence()
                    909:    movingaverage()
                    910:   varevsij() 
                    911:   if popbased==1 varevsij(,popbased)
                    912:   total life expectancies
                    913:   Variance of period (stable) prevalence
                    914:  end
                    915: */
                    916: 
1.187     brouard   917: /* #define DEBUG */
                    918: /* #define DEBUGBRENT */
1.203     brouard   919: /* #define DEBUGLINMIN */
                    920: /* #define DEBUGHESS */
                    921: #define DEBUGHESSIJ
1.224     brouard   922: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   923: #define POWELL /* Instead of NLOPT */
1.224     brouard   924: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   925: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    926: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   927: 
                    928: #include <math.h>
                    929: #include <stdio.h>
                    930: #include <stdlib.h>
                    931: #include <string.h>
1.226     brouard   932: #include <ctype.h>
1.159     brouard   933: 
                    934: #ifdef _WIN32
                    935: #include <io.h>
1.172     brouard   936: #include <windows.h>
                    937: #include <tchar.h>
1.159     brouard   938: #else
1.126     brouard   939: #include <unistd.h>
1.159     brouard   940: #endif
1.126     brouard   941: 
                    942: #include <limits.h>
                    943: #include <sys/types.h>
1.171     brouard   944: 
                    945: #if defined(__GNUC__)
                    946: #include <sys/utsname.h> /* Doesn't work on Windows */
                    947: #endif
                    948: 
1.126     brouard   949: #include <sys/stat.h>
                    950: #include <errno.h>
1.159     brouard   951: /* extern int errno; */
1.126     brouard   952: 
1.157     brouard   953: /* #ifdef LINUX */
                    954: /* #include <time.h> */
                    955: /* #include "timeval.h" */
                    956: /* #else */
                    957: /* #include <sys/time.h> */
                    958: /* #endif */
                    959: 
1.126     brouard   960: #include <time.h>
                    961: 
1.136     brouard   962: #ifdef GSL
                    963: #include <gsl/gsl_errno.h>
                    964: #include <gsl/gsl_multimin.h>
                    965: #endif
                    966: 
1.167     brouard   967: 
1.162     brouard   968: #ifdef NLOPT
                    969: #include <nlopt.h>
                    970: typedef struct {
                    971:   double (* function)(double [] );
                    972: } myfunc_data ;
                    973: #endif
                    974: 
1.126     brouard   975: /* #include <libintl.h> */
                    976: /* #define _(String) gettext (String) */
                    977: 
1.251     brouard   978: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   979: 
                    980: #define GNUPLOTPROGRAM "gnuplot"
                    981: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    982: #define FILENAMELENGTH 132
                    983: 
                    984: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    985: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    986: 
1.144     brouard   987: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    988: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   989: 
                    990: #define NINTERVMAX 8
1.144     brouard   991: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    992: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    993: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   994: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   995: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    996: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   997: #define MAXN 20000
1.144     brouard   998: #define YEARM 12. /**< Number of months per year */
1.218     brouard   999: /* #define AGESUP 130 */
                   1000: #define AGESUP 150
1.268     brouard  1001: #define AGEINF 0
1.218     brouard  1002: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1003: #define AGEBASE 40
1.194     brouard  1004: #define AGEOVERFLOW 1.e20
1.164     brouard  1005: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1006: #ifdef _WIN32
                   1007: #define DIRSEPARATOR '\\'
                   1008: #define CHARSEPARATOR "\\"
                   1009: #define ODIRSEPARATOR '/'
                   1010: #else
1.126     brouard  1011: #define DIRSEPARATOR '/'
                   1012: #define CHARSEPARATOR "/"
                   1013: #define ODIRSEPARATOR '\\'
                   1014: #endif
                   1015: 
1.271   ! brouard  1016: /* $Id: imach.c,v 1.270 2017/05/24 05:45:29 brouard Exp $ */
1.126     brouard  1017: /* $State: Exp $ */
1.196     brouard  1018: #include "version.h"
                   1019: char version[]=__IMACH_VERSION__;
1.224     brouard  1020: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.271   ! brouard  1021: char fullversion[]="$Revision: 1.270 $ $Date: 2017/05/24 05:45:29 $"; 
1.126     brouard  1022: char strstart[80];
                   1023: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1024: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1025: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1026: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1027: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1028: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1029: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1030: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1031: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1032: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1033: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1034: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1035: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1036: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1037: int nsd=0; /**< Total number of single dummy variables (output) */
                   1038: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1039: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1040: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1041: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1042: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1043: int cptcov=0; /* Working variable */
1.218     brouard  1044: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1045: int npar=NPARMAX;
                   1046: int nlstate=2; /* Number of live states */
                   1047: int ndeath=1; /* Number of dead states */
1.130     brouard  1048: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1049: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1050: int popbased=0;
                   1051: 
                   1052: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1053: int maxwav=0; /* Maxim number of waves */
                   1054: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1055: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1056: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1057:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1058: int mle=1, weightopt=0;
1.126     brouard  1059: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1060: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1061: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1062:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1063: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1064: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1065: 
1.130     brouard  1066: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1067: double **matprod2(); /* test */
1.126     brouard  1068: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1069: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1070: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1071: 
1.136     brouard  1072: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1073: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1074: FILE *ficlog, *ficrespow;
1.130     brouard  1075: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1076: double fretone; /* Only one call to likelihood */
1.130     brouard  1077: long ipmx=0; /* Number of contributions */
1.126     brouard  1078: double sw; /* Sum of weights */
                   1079: char filerespow[FILENAMELENGTH];
                   1080: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1081: FILE *ficresilk;
                   1082: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1083: FILE *ficresprobmorprev;
                   1084: FILE *fichtm, *fichtmcov; /* Html File */
                   1085: FILE *ficreseij;
                   1086: char filerese[FILENAMELENGTH];
                   1087: FILE *ficresstdeij;
                   1088: char fileresstde[FILENAMELENGTH];
                   1089: FILE *ficrescveij;
                   1090: char filerescve[FILENAMELENGTH];
                   1091: FILE  *ficresvij;
                   1092: char fileresv[FILENAMELENGTH];
1.269     brouard  1093: 
1.126     brouard  1094: char title[MAXLINE];
1.234     brouard  1095: char model[MAXLINE]; /**< The model line */
1.217     brouard  1096: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1097: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1098: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1099: char command[FILENAMELENGTH];
                   1100: int  outcmd=0;
                   1101: 
1.217     brouard  1102: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1103: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1104: char filelog[FILENAMELENGTH]; /* Log file */
                   1105: char filerest[FILENAMELENGTH];
                   1106: char fileregp[FILENAMELENGTH];
                   1107: char popfile[FILENAMELENGTH];
                   1108: 
                   1109: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1110: 
1.157     brouard  1111: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1112: /* struct timezone tzp; */
                   1113: /* extern int gettimeofday(); */
                   1114: struct tm tml, *gmtime(), *localtime();
                   1115: 
                   1116: extern time_t time();
                   1117: 
                   1118: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1119: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1120: struct tm tm;
                   1121: 
1.126     brouard  1122: char strcurr[80], strfor[80];
                   1123: 
                   1124: char *endptr;
                   1125: long lval;
                   1126: double dval;
                   1127: 
                   1128: #define NR_END 1
                   1129: #define FREE_ARG char*
                   1130: #define FTOL 1.0e-10
                   1131: 
                   1132: #define NRANSI 
1.240     brouard  1133: #define ITMAX 200
                   1134: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1135: 
                   1136: #define TOL 2.0e-4 
                   1137: 
                   1138: #define CGOLD 0.3819660 
                   1139: #define ZEPS 1.0e-10 
                   1140: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1141: 
                   1142: #define GOLD 1.618034 
                   1143: #define GLIMIT 100.0 
                   1144: #define TINY 1.0e-20 
                   1145: 
                   1146: static double maxarg1,maxarg2;
                   1147: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1148: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1149:   
                   1150: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1151: #define rint(a) floor(a+0.5)
1.166     brouard  1152: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1153: #define mytinydouble 1.0e-16
1.166     brouard  1154: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1155: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1156: /* static double dsqrarg; */
                   1157: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1158: static double sqrarg;
                   1159: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1160: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1161: int agegomp= AGEGOMP;
                   1162: 
                   1163: int imx; 
                   1164: int stepm=1;
                   1165: /* Stepm, step in month: minimum step interpolation*/
                   1166: 
                   1167: int estepm;
                   1168: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1169: 
                   1170: int m,nb;
                   1171: long *num;
1.197     brouard  1172: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1173: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1174:                   covariate for which somebody answered excluding 
                   1175:                   undefined. Usually 2: 0 and 1. */
                   1176: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1177:                             covariate for which somebody answered including 
                   1178:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1179: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1180: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1181: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1182: double *ageexmed,*agecens;
                   1183: double dateintmean=0;
                   1184: 
                   1185: double *weight;
                   1186: int **s; /* Status */
1.141     brouard  1187: double *agedc;
1.145     brouard  1188: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1189:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1190:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1191: double **coqvar; /* Fixed quantitative covariate nqv */
                   1192: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1193: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1194: double  idx; 
                   1195: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1196: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1197: /*k          1  2   3   4     5    6    7     8    9 */
                   1198: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1199: /* Tndvar[k]    1   2   3               4          5 */
                   1200: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1201: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1202: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1203: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1204: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1205: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1206: /* Tprod[i]=k           4               7            */
                   1207: /* Tage[i]=k                  5               8      */
                   1208: /* */
                   1209: /* Type                    */
                   1210: /* V         1  2  3  4  5 */
                   1211: /*           F  F  V  V  V */
                   1212: /*           D  Q  D  D  Q */
                   1213: /*                         */
                   1214: int *TvarsD;
                   1215: int *TvarsDind;
                   1216: int *TvarsQ;
                   1217: int *TvarsQind;
                   1218: 
1.235     brouard  1219: #define MAXRESULTLINES 10
                   1220: int nresult=0;
1.258     brouard  1221: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1222: int TKresult[MAXRESULTLINES];
1.237     brouard  1223: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1224: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1225: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1226: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1227: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1228: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1229: 
1.234     brouard  1230: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1231: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1232: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1233: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1234: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1235: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1236: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1237: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1238: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1239: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1240: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1241: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1242: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1243: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1244: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1245: 
1.230     brouard  1246: int *Tvarsel; /**< Selected covariates for output */
                   1247: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1248: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1249: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1250: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1251: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1252: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1253: int *Tage;
1.227     brouard  1254: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1255: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1256: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1257: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1258: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1259: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1260: int **Tvard;
                   1261: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1262: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1263: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1264:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1265:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1266: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1267: double *lsurv, *lpop, *tpop;
                   1268: 
1.231     brouard  1269: #define FD 1; /* Fixed dummy covariate */
                   1270: #define FQ 2; /* Fixed quantitative covariate */
                   1271: #define FP 3; /* Fixed product covariate */
                   1272: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1273: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1274: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1275: #define VD 10; /* Varying dummy covariate */
                   1276: #define VQ 11; /* Varying quantitative covariate */
                   1277: #define VP 12; /* Varying product covariate */
                   1278: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1279: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1280: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1281: #define APFD 16; /* Age product * fixed dummy covariate */
                   1282: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1283: #define APVD 18; /* Age product * varying dummy covariate */
                   1284: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1285: 
                   1286: #define FTYPE 1; /* Fixed covariate */
                   1287: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1288: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1289: 
                   1290: struct kmodel{
                   1291:        int maintype; /* main type */
                   1292:        int subtype; /* subtype */
                   1293: };
                   1294: struct kmodel modell[NCOVMAX];
                   1295: 
1.143     brouard  1296: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1297: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1298: 
                   1299: /**************** split *************************/
                   1300: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1301: {
                   1302:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1303:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1304:   */ 
                   1305:   char *ss;                            /* pointer */
1.186     brouard  1306:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1307: 
                   1308:   l1 = strlen(path );                  /* length of path */
                   1309:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1310:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1311:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1312:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1313:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1314:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1315:     /* get current working directory */
                   1316:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1317: #ifdef WIN32
                   1318:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1319: #else
                   1320:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1321: #endif
1.126     brouard  1322:       return( GLOCK_ERROR_GETCWD );
                   1323:     }
                   1324:     /* got dirc from getcwd*/
                   1325:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1326:   } else {                             /* strip directory from path */
1.126     brouard  1327:     ss++;                              /* after this, the filename */
                   1328:     l2 = strlen( ss );                 /* length of filename */
                   1329:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1330:     strcpy( name, ss );                /* save file name */
                   1331:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1332:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1333:     printf(" DIRC2 = %s \n",dirc);
                   1334:   }
                   1335:   /* We add a separator at the end of dirc if not exists */
                   1336:   l1 = strlen( dirc );                 /* length of directory */
                   1337:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1338:     dirc[l1] =  DIRSEPARATOR;
                   1339:     dirc[l1+1] = 0; 
                   1340:     printf(" DIRC3 = %s \n",dirc);
                   1341:   }
                   1342:   ss = strrchr( name, '.' );           /* find last / */
                   1343:   if (ss >0){
                   1344:     ss++;
                   1345:     strcpy(ext,ss);                    /* save extension */
                   1346:     l1= strlen( name);
                   1347:     l2= strlen(ss)+1;
                   1348:     strncpy( finame, name, l1-l2);
                   1349:     finame[l1-l2]= 0;
                   1350:   }
                   1351: 
                   1352:   return( 0 );                         /* we're done */
                   1353: }
                   1354: 
                   1355: 
                   1356: /******************************************/
                   1357: 
                   1358: void replace_back_to_slash(char *s, char*t)
                   1359: {
                   1360:   int i;
                   1361:   int lg=0;
                   1362:   i=0;
                   1363:   lg=strlen(t);
                   1364:   for(i=0; i<= lg; i++) {
                   1365:     (s[i] = t[i]);
                   1366:     if (t[i]== '\\') s[i]='/';
                   1367:   }
                   1368: }
                   1369: 
1.132     brouard  1370: char *trimbb(char *out, char *in)
1.137     brouard  1371: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1372:   char *s;
                   1373:   s=out;
                   1374:   while (*in != '\0'){
1.137     brouard  1375:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1376:       in++;
                   1377:     }
                   1378:     *out++ = *in++;
                   1379:   }
                   1380:   *out='\0';
                   1381:   return s;
                   1382: }
                   1383: 
1.187     brouard  1384: /* char *substrchaine(char *out, char *in, char *chain) */
                   1385: /* { */
                   1386: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1387: /*   char *s, *t; */
                   1388: /*   t=in;s=out; */
                   1389: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1390: /*     *out++ = *in++; */
                   1391: /*   } */
                   1392: 
                   1393: /*   /\* *in matches *chain *\/ */
                   1394: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1395: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1396: /*   } */
                   1397: /*   in--; chain--; */
                   1398: /*   while ( (*in != '\0')){ */
                   1399: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1400: /*     *out++ = *in++; */
                   1401: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1402: /*   } */
                   1403: /*   *out='\0'; */
                   1404: /*   out=s; */
                   1405: /*   return out; */
                   1406: /* } */
                   1407: char *substrchaine(char *out, char *in, char *chain)
                   1408: {
                   1409:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1410:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1411: 
                   1412:   char *strloc;
                   1413: 
                   1414:   strcpy (out, in); 
                   1415:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1416:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1417:   if(strloc != NULL){ 
                   1418:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1419:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1420:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1421:   }
                   1422:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1423:   return out;
                   1424: }
                   1425: 
                   1426: 
1.145     brouard  1427: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1428: {
1.187     brouard  1429:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1430:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1431:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1432:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1433:   */
1.160     brouard  1434:   char *s, *t;
1.145     brouard  1435:   t=in;s=in;
                   1436:   while ((*in != occ) && (*in != '\0')){
                   1437:     *alocc++ = *in++;
                   1438:   }
                   1439:   if( *in == occ){
                   1440:     *(alocc)='\0';
                   1441:     s=++in;
                   1442:   }
                   1443:  
                   1444:   if (s == t) {/* occ not found */
                   1445:     *(alocc-(in-s))='\0';
                   1446:     in=s;
                   1447:   }
                   1448:   while ( *in != '\0'){
                   1449:     *blocc++ = *in++;
                   1450:   }
                   1451: 
                   1452:   *blocc='\0';
                   1453:   return t;
                   1454: }
1.137     brouard  1455: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1456: {
1.187     brouard  1457:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1458:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1459:      gives blocc="abcdef2ghi" and alocc="j".
                   1460:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1461:   */
                   1462:   char *s, *t;
                   1463:   t=in;s=in;
                   1464:   while (*in != '\0'){
                   1465:     while( *in == occ){
                   1466:       *blocc++ = *in++;
                   1467:       s=in;
                   1468:     }
                   1469:     *blocc++ = *in++;
                   1470:   }
                   1471:   if (s == t) /* occ not found */
                   1472:     *(blocc-(in-s))='\0';
                   1473:   else
                   1474:     *(blocc-(in-s)-1)='\0';
                   1475:   in=s;
                   1476:   while ( *in != '\0'){
                   1477:     *alocc++ = *in++;
                   1478:   }
                   1479: 
                   1480:   *alocc='\0';
                   1481:   return s;
                   1482: }
                   1483: 
1.126     brouard  1484: int nbocc(char *s, char occ)
                   1485: {
                   1486:   int i,j=0;
                   1487:   int lg=20;
                   1488:   i=0;
                   1489:   lg=strlen(s);
                   1490:   for(i=0; i<= lg; i++) {
1.234     brouard  1491:     if  (s[i] == occ ) j++;
1.126     brouard  1492:   }
                   1493:   return j;
                   1494: }
                   1495: 
1.137     brouard  1496: /* void cutv(char *u,char *v, char*t, char occ) */
                   1497: /* { */
                   1498: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1499: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1500: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1501: /*   int i,lg,j,p=0; */
                   1502: /*   i=0; */
                   1503: /*   lg=strlen(t); */
                   1504: /*   for(j=0; j<=lg-1; j++) { */
                   1505: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1506: /*   } */
1.126     brouard  1507: 
1.137     brouard  1508: /*   for(j=0; j<p; j++) { */
                   1509: /*     (u[j] = t[j]); */
                   1510: /*   } */
                   1511: /*      u[p]='\0'; */
1.126     brouard  1512: 
1.137     brouard  1513: /*    for(j=0; j<= lg; j++) { */
                   1514: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1515: /*   } */
                   1516: /* } */
1.126     brouard  1517: 
1.160     brouard  1518: #ifdef _WIN32
                   1519: char * strsep(char **pp, const char *delim)
                   1520: {
                   1521:   char *p, *q;
                   1522:          
                   1523:   if ((p = *pp) == NULL)
                   1524:     return 0;
                   1525:   if ((q = strpbrk (p, delim)) != NULL)
                   1526:   {
                   1527:     *pp = q + 1;
                   1528:     *q = '\0';
                   1529:   }
                   1530:   else
                   1531:     *pp = 0;
                   1532:   return p;
                   1533: }
                   1534: #endif
                   1535: 
1.126     brouard  1536: /********************** nrerror ********************/
                   1537: 
                   1538: void nrerror(char error_text[])
                   1539: {
                   1540:   fprintf(stderr,"ERREUR ...\n");
                   1541:   fprintf(stderr,"%s\n",error_text);
                   1542:   exit(EXIT_FAILURE);
                   1543: }
                   1544: /*********************** vector *******************/
                   1545: double *vector(int nl, int nh)
                   1546: {
                   1547:   double *v;
                   1548:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1549:   if (!v) nrerror("allocation failure in vector");
                   1550:   return v-nl+NR_END;
                   1551: }
                   1552: 
                   1553: /************************ free vector ******************/
                   1554: void free_vector(double*v, int nl, int nh)
                   1555: {
                   1556:   free((FREE_ARG)(v+nl-NR_END));
                   1557: }
                   1558: 
                   1559: /************************ivector *******************************/
                   1560: int *ivector(long nl,long nh)
                   1561: {
                   1562:   int *v;
                   1563:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1564:   if (!v) nrerror("allocation failure in ivector");
                   1565:   return v-nl+NR_END;
                   1566: }
                   1567: 
                   1568: /******************free ivector **************************/
                   1569: void free_ivector(int *v, long nl, long nh)
                   1570: {
                   1571:   free((FREE_ARG)(v+nl-NR_END));
                   1572: }
                   1573: 
                   1574: /************************lvector *******************************/
                   1575: long *lvector(long nl,long nh)
                   1576: {
                   1577:   long *v;
                   1578:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1579:   if (!v) nrerror("allocation failure in ivector");
                   1580:   return v-nl+NR_END;
                   1581: }
                   1582: 
                   1583: /******************free lvector **************************/
                   1584: void free_lvector(long *v, long nl, long nh)
                   1585: {
                   1586:   free((FREE_ARG)(v+nl-NR_END));
                   1587: }
                   1588: 
                   1589: /******************* imatrix *******************************/
                   1590: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1591:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1592: { 
                   1593:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1594:   int **m; 
                   1595:   
                   1596:   /* allocate pointers to rows */ 
                   1597:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1598:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1599:   m += NR_END; 
                   1600:   m -= nrl; 
                   1601:   
                   1602:   
                   1603:   /* allocate rows and set pointers to them */ 
                   1604:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1605:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1606:   m[nrl] += NR_END; 
                   1607:   m[nrl] -= ncl; 
                   1608:   
                   1609:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1610:   
                   1611:   /* return pointer to array of pointers to rows */ 
                   1612:   return m; 
                   1613: } 
                   1614: 
                   1615: /****************** free_imatrix *************************/
                   1616: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1617:       int **m;
                   1618:       long nch,ncl,nrh,nrl; 
                   1619:      /* free an int matrix allocated by imatrix() */ 
                   1620: { 
                   1621:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1622:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1623: } 
                   1624: 
                   1625: /******************* matrix *******************************/
                   1626: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1627: {
                   1628:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1629:   double **m;
                   1630: 
                   1631:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1632:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1633:   m += NR_END;
                   1634:   m -= nrl;
                   1635: 
                   1636:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1637:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1638:   m[nrl] += NR_END;
                   1639:   m[nrl] -= ncl;
                   1640: 
                   1641:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1642:   return m;
1.145     brouard  1643:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1644: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1645: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1646:    */
                   1647: }
                   1648: 
                   1649: /*************************free matrix ************************/
                   1650: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1651: {
                   1652:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1653:   free((FREE_ARG)(m+nrl-NR_END));
                   1654: }
                   1655: 
                   1656: /******************* ma3x *******************************/
                   1657: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1658: {
                   1659:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1660:   double ***m;
                   1661: 
                   1662:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1663:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1664:   m += NR_END;
                   1665:   m -= nrl;
                   1666: 
                   1667:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1668:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1669:   m[nrl] += NR_END;
                   1670:   m[nrl] -= ncl;
                   1671: 
                   1672:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1673: 
                   1674:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1675:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1676:   m[nrl][ncl] += NR_END;
                   1677:   m[nrl][ncl] -= nll;
                   1678:   for (j=ncl+1; j<=nch; j++) 
                   1679:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1680:   
                   1681:   for (i=nrl+1; i<=nrh; i++) {
                   1682:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1683:     for (j=ncl+1; j<=nch; j++) 
                   1684:       m[i][j]=m[i][j-1]+nlay;
                   1685:   }
                   1686:   return m; 
                   1687:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1688:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1689:   */
                   1690: }
                   1691: 
                   1692: /*************************free ma3x ************************/
                   1693: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1694: {
                   1695:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1696:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1697:   free((FREE_ARG)(m+nrl-NR_END));
                   1698: }
                   1699: 
                   1700: /*************** function subdirf ***********/
                   1701: char *subdirf(char fileres[])
                   1702: {
                   1703:   /* Caution optionfilefiname is hidden */
                   1704:   strcpy(tmpout,optionfilefiname);
                   1705:   strcat(tmpout,"/"); /* Add to the right */
                   1706:   strcat(tmpout,fileres);
                   1707:   return tmpout;
                   1708: }
                   1709: 
                   1710: /*************** function subdirf2 ***********/
                   1711: char *subdirf2(char fileres[], char *preop)
                   1712: {
                   1713:   
                   1714:   /* Caution optionfilefiname is hidden */
                   1715:   strcpy(tmpout,optionfilefiname);
                   1716:   strcat(tmpout,"/");
                   1717:   strcat(tmpout,preop);
                   1718:   strcat(tmpout,fileres);
                   1719:   return tmpout;
                   1720: }
                   1721: 
                   1722: /*************** function subdirf3 ***********/
                   1723: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1724: {
                   1725:   
                   1726:   /* Caution optionfilefiname is hidden */
                   1727:   strcpy(tmpout,optionfilefiname);
                   1728:   strcat(tmpout,"/");
                   1729:   strcat(tmpout,preop);
                   1730:   strcat(tmpout,preop2);
                   1731:   strcat(tmpout,fileres);
                   1732:   return tmpout;
                   1733: }
1.213     brouard  1734:  
                   1735: /*************** function subdirfext ***********/
                   1736: char *subdirfext(char fileres[], char *preop, char *postop)
                   1737: {
                   1738:   
                   1739:   strcpy(tmpout,preop);
                   1740:   strcat(tmpout,fileres);
                   1741:   strcat(tmpout,postop);
                   1742:   return tmpout;
                   1743: }
1.126     brouard  1744: 
1.213     brouard  1745: /*************** function subdirfext3 ***********/
                   1746: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1747: {
                   1748:   
                   1749:   /* Caution optionfilefiname is hidden */
                   1750:   strcpy(tmpout,optionfilefiname);
                   1751:   strcat(tmpout,"/");
                   1752:   strcat(tmpout,preop);
                   1753:   strcat(tmpout,fileres);
                   1754:   strcat(tmpout,postop);
                   1755:   return tmpout;
                   1756: }
                   1757:  
1.162     brouard  1758: char *asc_diff_time(long time_sec, char ascdiff[])
                   1759: {
                   1760:   long sec_left, days, hours, minutes;
                   1761:   days = (time_sec) / (60*60*24);
                   1762:   sec_left = (time_sec) % (60*60*24);
                   1763:   hours = (sec_left) / (60*60) ;
                   1764:   sec_left = (sec_left) %(60*60);
                   1765:   minutes = (sec_left) /60;
                   1766:   sec_left = (sec_left) % (60);
                   1767:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1768:   return ascdiff;
                   1769: }
                   1770: 
1.126     brouard  1771: /***************** f1dim *************************/
                   1772: extern int ncom; 
                   1773: extern double *pcom,*xicom;
                   1774: extern double (*nrfunc)(double []); 
                   1775:  
                   1776: double f1dim(double x) 
                   1777: { 
                   1778:   int j; 
                   1779:   double f;
                   1780:   double *xt; 
                   1781:  
                   1782:   xt=vector(1,ncom); 
                   1783:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1784:   f=(*nrfunc)(xt); 
                   1785:   free_vector(xt,1,ncom); 
                   1786:   return f; 
                   1787: } 
                   1788: 
                   1789: /*****************brent *************************/
                   1790: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1791: {
                   1792:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1793:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1794:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1795:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1796:    * returned function value. 
                   1797:   */
1.126     brouard  1798:   int iter; 
                   1799:   double a,b,d,etemp;
1.159     brouard  1800:   double fu=0,fv,fw,fx;
1.164     brouard  1801:   double ftemp=0.;
1.126     brouard  1802:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1803:   double e=0.0; 
                   1804:  
                   1805:   a=(ax < cx ? ax : cx); 
                   1806:   b=(ax > cx ? ax : cx); 
                   1807:   x=w=v=bx; 
                   1808:   fw=fv=fx=(*f)(x); 
                   1809:   for (iter=1;iter<=ITMAX;iter++) { 
                   1810:     xm=0.5*(a+b); 
                   1811:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1812:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1813:     printf(".");fflush(stdout);
                   1814:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1815: #ifdef DEBUGBRENT
1.126     brouard  1816:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1817:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1818:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1819: #endif
                   1820:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1821:       *xmin=x; 
                   1822:       return fx; 
                   1823:     } 
                   1824:     ftemp=fu;
                   1825:     if (fabs(e) > tol1) { 
                   1826:       r=(x-w)*(fx-fv); 
                   1827:       q=(x-v)*(fx-fw); 
                   1828:       p=(x-v)*q-(x-w)*r; 
                   1829:       q=2.0*(q-r); 
                   1830:       if (q > 0.0) p = -p; 
                   1831:       q=fabs(q); 
                   1832:       etemp=e; 
                   1833:       e=d; 
                   1834:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1835:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1836:       else { 
1.224     brouard  1837:                                d=p/q; 
                   1838:                                u=x+d; 
                   1839:                                if (u-a < tol2 || b-u < tol2) 
                   1840:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1841:       } 
                   1842:     } else { 
                   1843:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1844:     } 
                   1845:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1846:     fu=(*f)(u); 
                   1847:     if (fu <= fx) { 
                   1848:       if (u >= x) a=x; else b=x; 
                   1849:       SHFT(v,w,x,u) 
1.183     brouard  1850:       SHFT(fv,fw,fx,fu) 
                   1851:     } else { 
                   1852:       if (u < x) a=u; else b=u; 
                   1853:       if (fu <= fw || w == x) { 
1.224     brouard  1854:                                v=w; 
                   1855:                                w=u; 
                   1856:                                fv=fw; 
                   1857:                                fw=fu; 
1.183     brouard  1858:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1859:                                v=u; 
                   1860:                                fv=fu; 
1.183     brouard  1861:       } 
                   1862:     } 
1.126     brouard  1863:   } 
                   1864:   nrerror("Too many iterations in brent"); 
                   1865:   *xmin=x; 
                   1866:   return fx; 
                   1867: } 
                   1868: 
                   1869: /****************** mnbrak ***********************/
                   1870: 
                   1871: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1872:            double (*func)(double)) 
1.183     brouard  1873: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1874: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1875: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1876: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1877:    */
1.126     brouard  1878:   double ulim,u,r,q, dum;
                   1879:   double fu; 
1.187     brouard  1880: 
                   1881:   double scale=10.;
                   1882:   int iterscale=0;
                   1883: 
                   1884:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1885:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1886: 
                   1887: 
                   1888:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1889:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1890:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1891:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1892:   /* } */
                   1893: 
1.126     brouard  1894:   if (*fb > *fa) { 
                   1895:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1896:     SHFT(dum,*fb,*fa,dum) 
                   1897:   } 
1.126     brouard  1898:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1899:   *fc=(*func)(*cx); 
1.183     brouard  1900: #ifdef DEBUG
1.224     brouard  1901:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1902:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1903: #endif
1.224     brouard  1904:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1905:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1906:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1907:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1908:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1909:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1910:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1911:       fu=(*func)(u); 
1.163     brouard  1912: #ifdef DEBUG
                   1913:       /* f(x)=A(x-u)**2+f(u) */
                   1914:       double A, fparabu; 
                   1915:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1916:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1917:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1918:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1919:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1920:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1921:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1922:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1923: #endif 
1.184     brouard  1924: #ifdef MNBRAKORIGINAL
1.183     brouard  1925: #else
1.191     brouard  1926: /*       if (fu > *fc) { */
                   1927: /* #ifdef DEBUG */
                   1928: /*       printf("mnbrak4  fu > fc \n"); */
                   1929: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1930: /* #endif */
                   1931: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1932: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1933: /*     dum=u; /\* Shifting c and u *\/ */
                   1934: /*     u = *cx; */
                   1935: /*     *cx = dum; */
                   1936: /*     dum = fu; */
                   1937: /*     fu = *fc; */
                   1938: /*     *fc =dum; */
                   1939: /*       } else { /\* end *\/ */
                   1940: /* #ifdef DEBUG */
                   1941: /*       printf("mnbrak3  fu < fc \n"); */
                   1942: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1943: /* #endif */
                   1944: /*     dum=u; /\* Shifting c and u *\/ */
                   1945: /*     u = *cx; */
                   1946: /*     *cx = dum; */
                   1947: /*     dum = fu; */
                   1948: /*     fu = *fc; */
                   1949: /*     *fc =dum; */
                   1950: /*       } */
1.224     brouard  1951: #ifdef DEBUGMNBRAK
                   1952:                 double A, fparabu; 
                   1953:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1954:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1955:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1956:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1957: #endif
1.191     brouard  1958:       dum=u; /* Shifting c and u */
                   1959:       u = *cx;
                   1960:       *cx = dum;
                   1961:       dum = fu;
                   1962:       fu = *fc;
                   1963:       *fc =dum;
1.183     brouard  1964: #endif
1.162     brouard  1965:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1966: #ifdef DEBUG
1.224     brouard  1967:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1968:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1969: #endif
1.126     brouard  1970:       fu=(*func)(u); 
                   1971:       if (fu < *fc) { 
1.183     brouard  1972: #ifdef DEBUG
1.224     brouard  1973:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1974:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1975: #endif
                   1976:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1977:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1978: #ifdef DEBUG
                   1979:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1980: #endif
                   1981:       } 
1.162     brouard  1982:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1983: #ifdef DEBUG
1.224     brouard  1984:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1985:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1986: #endif
1.126     brouard  1987:       u=ulim; 
                   1988:       fu=(*func)(u); 
1.183     brouard  1989:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1990: #ifdef DEBUG
1.224     brouard  1991:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1992:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1993: #endif
1.126     brouard  1994:       u=(*cx)+GOLD*(*cx-*bx); 
                   1995:       fu=(*func)(u); 
1.224     brouard  1996: #ifdef DEBUG
                   1997:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1998:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1999: #endif
1.183     brouard  2000:     } /* end tests */
1.126     brouard  2001:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2002:     SHFT(*fa,*fb,*fc,fu) 
                   2003: #ifdef DEBUG
1.224     brouard  2004:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2005:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2006: #endif
                   2007:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2008: } 
                   2009: 
                   2010: /*************** linmin ************************/
1.162     brouard  2011: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2012: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2013: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2014: the value of func at the returned location p . This is actually all accomplished by calling the
                   2015: routines mnbrak and brent .*/
1.126     brouard  2016: int ncom; 
                   2017: double *pcom,*xicom;
                   2018: double (*nrfunc)(double []); 
                   2019:  
1.224     brouard  2020: #ifdef LINMINORIGINAL
1.126     brouard  2021: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2022: #else
                   2023: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2024: #endif
1.126     brouard  2025: { 
                   2026:   double brent(double ax, double bx, double cx, 
                   2027:               double (*f)(double), double tol, double *xmin); 
                   2028:   double f1dim(double x); 
                   2029:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2030:              double *fc, double (*func)(double)); 
                   2031:   int j; 
                   2032:   double xx,xmin,bx,ax; 
                   2033:   double fx,fb,fa;
1.187     brouard  2034: 
1.203     brouard  2035: #ifdef LINMINORIGINAL
                   2036: #else
                   2037:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2038: #endif
                   2039:   
1.126     brouard  2040:   ncom=n; 
                   2041:   pcom=vector(1,n); 
                   2042:   xicom=vector(1,n); 
                   2043:   nrfunc=func; 
                   2044:   for (j=1;j<=n;j++) { 
                   2045:     pcom[j]=p[j]; 
1.202     brouard  2046:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2047:   } 
1.187     brouard  2048: 
1.203     brouard  2049: #ifdef LINMINORIGINAL
                   2050:   xx=1.;
                   2051: #else
                   2052:   axs=0.0;
                   2053:   xxs=1.;
                   2054:   do{
                   2055:     xx= xxs;
                   2056: #endif
1.187     brouard  2057:     ax=0.;
                   2058:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2059:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2060:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2061:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2062:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2063:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2064:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2065: #ifdef LINMINORIGINAL
                   2066: #else
                   2067:     if (fx != fx){
1.224     brouard  2068:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2069:                        printf("|");
                   2070:                        fprintf(ficlog,"|");
1.203     brouard  2071: #ifdef DEBUGLINMIN
1.224     brouard  2072:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2073: #endif
                   2074:     }
1.224     brouard  2075:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2076: #endif
                   2077:   
1.191     brouard  2078: #ifdef DEBUGLINMIN
                   2079:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2080:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2081: #endif
1.224     brouard  2082: #ifdef LINMINORIGINAL
                   2083: #else
                   2084:        if(fb == fx){ /* Flat function in the direction */
                   2085:                xmin=xx;
                   2086:     *flat=1;
                   2087:        }else{
                   2088:     *flat=0;
                   2089: #endif
                   2090:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2091:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2092:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2093:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2094:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2095:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2096: #ifdef DEBUG
1.224     brouard  2097:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2098:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2099: #endif
                   2100: #ifdef LINMINORIGINAL
                   2101: #else
                   2102:                        }
1.126     brouard  2103: #endif
1.191     brouard  2104: #ifdef DEBUGLINMIN
                   2105:   printf("linmin end ");
1.202     brouard  2106:   fprintf(ficlog,"linmin end ");
1.191     brouard  2107: #endif
1.126     brouard  2108:   for (j=1;j<=n;j++) { 
1.203     brouard  2109: #ifdef LINMINORIGINAL
                   2110:     xi[j] *= xmin; 
                   2111: #else
                   2112: #ifdef DEBUGLINMIN
                   2113:     if(xxs <1.0)
                   2114:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2115: #endif
                   2116:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2117: #ifdef DEBUGLINMIN
                   2118:     if(xxs <1.0)
                   2119:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2120: #endif
                   2121: #endif
1.187     brouard  2122:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2123:   } 
1.191     brouard  2124: #ifdef DEBUGLINMIN
1.203     brouard  2125:   printf("\n");
1.191     brouard  2126:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2127:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2128:   for (j=1;j<=n;j++) { 
1.202     brouard  2129:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2130:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2131:     if(j % ncovmodel == 0){
1.191     brouard  2132:       printf("\n");
1.202     brouard  2133:       fprintf(ficlog,"\n");
                   2134:     }
1.191     brouard  2135:   }
1.203     brouard  2136: #else
1.191     brouard  2137: #endif
1.126     brouard  2138:   free_vector(xicom,1,n); 
                   2139:   free_vector(pcom,1,n); 
                   2140: } 
                   2141: 
                   2142: 
                   2143: /*************** powell ************************/
1.162     brouard  2144: /*
                   2145: Minimization of a function func of n variables. Input consists of an initial starting point
                   2146: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2147: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2148: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2149: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2150: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2151:  */
1.224     brouard  2152: #ifdef LINMINORIGINAL
                   2153: #else
                   2154:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2155:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2156: #endif
1.126     brouard  2157: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2158:            double (*func)(double [])) 
                   2159: { 
1.224     brouard  2160: #ifdef LINMINORIGINAL
                   2161:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2162:              double (*func)(double [])); 
1.224     brouard  2163: #else 
1.241     brouard  2164:  void linmin(double p[], double xi[], int n, double *fret,
                   2165:             double (*func)(double []),int *flat); 
1.224     brouard  2166: #endif
1.239     brouard  2167:  int i,ibig,j,jk,k; 
1.126     brouard  2168:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2169:   double directest;
1.126     brouard  2170:   double fp,fptt;
                   2171:   double *xits;
                   2172:   int niterf, itmp;
1.224     brouard  2173: #ifdef LINMINORIGINAL
                   2174: #else
                   2175: 
                   2176:   flatdir=ivector(1,n); 
                   2177:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2178: #endif
1.126     brouard  2179: 
                   2180:   pt=vector(1,n); 
                   2181:   ptt=vector(1,n); 
                   2182:   xit=vector(1,n); 
                   2183:   xits=vector(1,n); 
                   2184:   *fret=(*func)(p); 
                   2185:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2186:   rcurr_time = time(NULL);  
1.126     brouard  2187:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2188:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2189:     ibig=0; 
                   2190:     del=0.0; 
1.157     brouard  2191:     rlast_time=rcurr_time;
                   2192:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2193:     rcurr_time = time(NULL);  
                   2194:     curr_time = *localtime(&rcurr_time);
                   2195:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2196:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2197: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2198:     for (i=1;i<=n;i++) {
1.126     brouard  2199:       fprintf(ficrespow," %.12lf", p[i]);
                   2200:     }
1.239     brouard  2201:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2202:     printf("\n#model=  1      +     age ");
                   2203:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2204:     if(nagesqr==1){
1.241     brouard  2205:        printf("  + age*age  ");
                   2206:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2207:     }
                   2208:     for(j=1;j <=ncovmodel-2;j++){
                   2209:       if(Typevar[j]==0) {
                   2210:        printf("  +      V%d  ",Tvar[j]);
                   2211:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2212:       }else if(Typevar[j]==1) {
                   2213:        printf("  +    V%d*age ",Tvar[j]);
                   2214:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2215:       }else if(Typevar[j]==2) {
                   2216:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2217:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2218:       }
                   2219:     }
1.126     brouard  2220:     printf("\n");
1.239     brouard  2221: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2222: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2223:     fprintf(ficlog,"\n");
1.239     brouard  2224:     for(i=1,jk=1; i <=nlstate; i++){
                   2225:       for(k=1; k <=(nlstate+ndeath); k++){
                   2226:        if (k != i) {
                   2227:          printf("%d%d ",i,k);
                   2228:          fprintf(ficlog,"%d%d ",i,k);
                   2229:          for(j=1; j <=ncovmodel; j++){
                   2230:            printf("%12.7f ",p[jk]);
                   2231:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2232:            jk++; 
                   2233:          }
                   2234:          printf("\n");
                   2235:          fprintf(ficlog,"\n");
                   2236:        }
                   2237:       }
                   2238:     }
1.241     brouard  2239:     if(*iter <=3 && *iter >1){
1.157     brouard  2240:       tml = *localtime(&rcurr_time);
                   2241:       strcpy(strcurr,asctime(&tml));
                   2242:       rforecast_time=rcurr_time; 
1.126     brouard  2243:       itmp = strlen(strcurr);
                   2244:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2245:        strcurr[itmp-1]='\0';
1.162     brouard  2246:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2247:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2248:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2249:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2250:        forecast_time = *localtime(&rforecast_time);
                   2251:        strcpy(strfor,asctime(&forecast_time));
                   2252:        itmp = strlen(strfor);
                   2253:        if(strfor[itmp-1]=='\n')
                   2254:          strfor[itmp-1]='\0';
                   2255:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2256:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2257:       }
                   2258:     }
1.187     brouard  2259:     for (i=1;i<=n;i++) { /* For each direction i */
                   2260:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2261:       fptt=(*fret); 
                   2262: #ifdef DEBUG
1.203     brouard  2263:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2264:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2265: #endif
1.203     brouard  2266:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2267:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2268: #ifdef LINMINORIGINAL
1.188     brouard  2269:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2270: #else
                   2271:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2272:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2273: #endif
                   2274:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2275:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2276:                                /* because that direction will be replaced unless the gain del is small */
                   2277:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2278:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2279:                                /* with the new direction. */
                   2280:                                del=fabs(fptt-(*fret)); 
                   2281:                                ibig=i; 
1.126     brouard  2282:       } 
                   2283: #ifdef DEBUG
                   2284:       printf("%d %.12e",i,(*fret));
                   2285:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2286:       for (j=1;j<=n;j++) {
1.224     brouard  2287:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2288:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2289:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2290:       }
                   2291:       for(j=1;j<=n;j++) {
1.225     brouard  2292:                                printf(" p(%d)=%.12e",j,p[j]);
                   2293:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2294:       }
                   2295:       printf("\n");
                   2296:       fprintf(ficlog,"\n");
                   2297: #endif
1.187     brouard  2298:     } /* end loop on each direction i */
                   2299:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2300:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2301:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2302:       for(j=1;j<=n;j++) {
1.225     brouard  2303:                                if(flatdir[j] >0){
                   2304:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2305:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2306:                                }
                   2307:                                /* printf("\n"); */
                   2308:                                /* fprintf(ficlog,"\n"); */
                   2309:                        }
1.243     brouard  2310:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2311:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2312:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2313:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2314:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2315:       /* decreased of more than 3.84  */
                   2316:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2317:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2318:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2319:                        
1.188     brouard  2320:       /* Starting the program with initial values given by a former maximization will simply change */
                   2321:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2322:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2323:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2324: #ifdef DEBUG
                   2325:       int k[2],l;
                   2326:       k[0]=1;
                   2327:       k[1]=-1;
                   2328:       printf("Max: %.12e",(*func)(p));
                   2329:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2330:       for (j=1;j<=n;j++) {
                   2331:        printf(" %.12e",p[j]);
                   2332:        fprintf(ficlog," %.12e",p[j]);
                   2333:       }
                   2334:       printf("\n");
                   2335:       fprintf(ficlog,"\n");
                   2336:       for(l=0;l<=1;l++) {
                   2337:        for (j=1;j<=n;j++) {
                   2338:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2339:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2340:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2341:        }
                   2342:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2343:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2344:       }
                   2345: #endif
                   2346: 
1.224     brouard  2347: #ifdef LINMINORIGINAL
                   2348: #else
                   2349:       free_ivector(flatdir,1,n); 
                   2350: #endif
1.126     brouard  2351:       free_vector(xit,1,n); 
                   2352:       free_vector(xits,1,n); 
                   2353:       free_vector(ptt,1,n); 
                   2354:       free_vector(pt,1,n); 
                   2355:       return; 
1.192     brouard  2356:     } /* enough precision */ 
1.240     brouard  2357:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2358:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2359:       ptt[j]=2.0*p[j]-pt[j]; 
                   2360:       xit[j]=p[j]-pt[j]; 
                   2361:       pt[j]=p[j]; 
                   2362:     } 
1.181     brouard  2363:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2364: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2365:                if (*iter <=4) {
1.225     brouard  2366: #else
                   2367: #endif
1.224     brouard  2368: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2369: #else
1.161     brouard  2370:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2371: #endif
1.162     brouard  2372:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2373:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2374:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2375:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2376:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2377:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2378:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2379:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2380:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2381:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2382:       /* mu² and del² are equal when f3=f1 */
                   2383:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2384:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2385:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2386:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2387: #ifdef NRCORIGINAL
                   2388:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2389: #else
                   2390:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2391:       t= t- del*SQR(fp-fptt);
1.183     brouard  2392: #endif
1.202     brouard  2393:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2394: #ifdef DEBUG
1.181     brouard  2395:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2396:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2397:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2398:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2399:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2400:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2401:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2402:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2403: #endif
1.183     brouard  2404: #ifdef POWELLORIGINAL
                   2405:       if (t < 0.0) { /* Then we use it for new direction */
                   2406: #else
1.182     brouard  2407:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2408:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2409:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2410:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2411:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2412:       } 
1.181     brouard  2413:       if (directest < 0.0) { /* Then we use it for new direction */
                   2414: #endif
1.191     brouard  2415: #ifdef DEBUGLINMIN
1.234     brouard  2416:        printf("Before linmin in direction P%d-P0\n",n);
                   2417:        for (j=1;j<=n;j++) {
                   2418:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2419:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2420:          if(j % ncovmodel == 0){
                   2421:            printf("\n");
                   2422:            fprintf(ficlog,"\n");
                   2423:          }
                   2424:        }
1.224     brouard  2425: #endif
                   2426: #ifdef LINMINORIGINAL
1.234     brouard  2427:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2428: #else
1.234     brouard  2429:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2430:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2431: #endif
1.234     brouard  2432:        
1.191     brouard  2433: #ifdef DEBUGLINMIN
1.234     brouard  2434:        for (j=1;j<=n;j++) { 
                   2435:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2436:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2437:          if(j % ncovmodel == 0){
                   2438:            printf("\n");
                   2439:            fprintf(ficlog,"\n");
                   2440:          }
                   2441:        }
1.224     brouard  2442: #endif
1.234     brouard  2443:        for (j=1;j<=n;j++) { 
                   2444:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2445:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2446:        }
1.224     brouard  2447: #ifdef LINMINORIGINAL
                   2448: #else
1.234     brouard  2449:        for (j=1, flatd=0;j<=n;j++) {
                   2450:          if(flatdir[j]>0)
                   2451:            flatd++;
                   2452:        }
                   2453:        if(flatd >0){
1.255     brouard  2454:          printf("%d flat directions: ",flatd);
                   2455:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2456:          for (j=1;j<=n;j++) { 
                   2457:            if(flatdir[j]>0){
                   2458:              printf("%d ",j);
                   2459:              fprintf(ficlog,"%d ",j);
                   2460:            }
                   2461:          }
                   2462:          printf("\n");
                   2463:          fprintf(ficlog,"\n");
                   2464:        }
1.191     brouard  2465: #endif
1.234     brouard  2466:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2467:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2468:        
1.126     brouard  2469: #ifdef DEBUG
1.234     brouard  2470:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2471:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2472:        for(j=1;j<=n;j++){
                   2473:          printf(" %lf",xit[j]);
                   2474:          fprintf(ficlog," %lf",xit[j]);
                   2475:        }
                   2476:        printf("\n");
                   2477:        fprintf(ficlog,"\n");
1.126     brouard  2478: #endif
1.192     brouard  2479:       } /* end of t or directest negative */
1.224     brouard  2480: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2481: #else
1.234     brouard  2482:       } /* end if (fptt < fp)  */
1.192     brouard  2483: #endif
1.225     brouard  2484: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2485:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2486: #else
1.224     brouard  2487: #endif
1.234     brouard  2488:                } /* loop iteration */ 
1.126     brouard  2489: } 
1.234     brouard  2490:   
1.126     brouard  2491: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2492:   
1.235     brouard  2493:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2494:   {
1.235     brouard  2495:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2496:        (and selected quantitative values in nres)
                   2497:        by left multiplying the unit
1.234     brouard  2498:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2499:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2500:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2501:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2502:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2503:   /* Initial matrix pimij */
                   2504:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2505:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2506:   /*  0,                   0                  , 1} */
                   2507:   /*
                   2508:    * and after some iteration: */
                   2509:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2510:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2511:   /*  0,                   0                  , 1} */
                   2512:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2513:   /* {0.51571254859325999, 0.4842874514067399, */
                   2514:   /*  0.51326036147820708, 0.48673963852179264} */
                   2515:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2516:     
1.126     brouard  2517:   int i, ii,j,k;
1.209     brouard  2518:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2519:   /* double **matprod2(); */ /* test */
1.218     brouard  2520:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2521:   double **newm;
1.209     brouard  2522:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2523:   int ncvloop=0;
1.169     brouard  2524:   
1.209     brouard  2525:   min=vector(1,nlstate);
                   2526:   max=vector(1,nlstate);
                   2527:   meandiff=vector(1,nlstate);
                   2528: 
1.218     brouard  2529:        /* Starting with matrix unity */
1.126     brouard  2530:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2531:     for (j=1;j<=nlstate+ndeath;j++){
                   2532:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2533:     }
1.169     brouard  2534:   
                   2535:   cov[1]=1.;
                   2536:   
                   2537:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2538:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2539:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2540:     ncvloop++;
1.126     brouard  2541:     newm=savm;
                   2542:     /* Covariates have to be included here again */
1.138     brouard  2543:     cov[2]=agefin;
1.187     brouard  2544:     if(nagesqr==1)
                   2545:       cov[3]= agefin*agefin;;
1.234     brouard  2546:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2547:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2548:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2549:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2550:     }
                   2551:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2552:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2553:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2554:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2555:     }
1.237     brouard  2556:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2557:       if(Dummy[Tvar[Tage[k]]]){
                   2558:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2559:       } else{
1.235     brouard  2560:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2561:       }
1.235     brouard  2562:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2563:     }
1.237     brouard  2564:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2565:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2566:       if(Dummy[Tvard[k][1]==0]){
                   2567:        if(Dummy[Tvard[k][2]==0]){
                   2568:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2569:        }else{
                   2570:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2571:        }
                   2572:       }else{
                   2573:        if(Dummy[Tvard[k][2]==0]){
                   2574:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2575:        }else{
                   2576:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2577:        }
                   2578:       }
1.234     brouard  2579:     }
1.138     brouard  2580:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2581:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2582:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2583:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2584:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2585:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2586:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2587:     
1.126     brouard  2588:     savm=oldm;
                   2589:     oldm=newm;
1.209     brouard  2590: 
                   2591:     for(j=1; j<=nlstate; j++){
                   2592:       max[j]=0.;
                   2593:       min[j]=1.;
                   2594:     }
                   2595:     for(i=1;i<=nlstate;i++){
                   2596:       sumnew=0;
                   2597:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2598:       for(j=1; j<=nlstate; j++){ 
                   2599:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2600:        max[j]=FMAX(max[j],prlim[i][j]);
                   2601:        min[j]=FMIN(min[j],prlim[i][j]);
                   2602:       }
                   2603:     }
                   2604: 
1.126     brouard  2605:     maxmax=0.;
1.209     brouard  2606:     for(j=1; j<=nlstate; j++){
                   2607:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2608:       maxmax=FMAX(maxmax,meandiff[j]);
                   2609:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2610:     } /* j loop */
1.203     brouard  2611:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2612:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2613:     if(maxmax < ftolpl){
1.209     brouard  2614:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2615:       free_vector(min,1,nlstate);
                   2616:       free_vector(max,1,nlstate);
                   2617:       free_vector(meandiff,1,nlstate);
1.126     brouard  2618:       return prlim;
                   2619:     }
1.169     brouard  2620:   } /* age loop */
1.208     brouard  2621:     /* After some age loop it doesn't converge */
1.209     brouard  2622:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2623: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2624:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2625:   free_vector(min,1,nlstate);
                   2626:   free_vector(max,1,nlstate);
                   2627:   free_vector(meandiff,1,nlstate);
1.208     brouard  2628:   
1.169     brouard  2629:   return prlim; /* should not reach here */
1.126     brouard  2630: }
                   2631: 
1.217     brouard  2632: 
                   2633:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2634: 
1.218     brouard  2635:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2636:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2637:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2638: {
1.264     brouard  2639:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2640:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2641:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2642:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2643:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2644:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2645:   /* Initial matrix pimij */
                   2646:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2647:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2648:   /*  0,                   0                  , 1} */
                   2649:   /*
                   2650:    * and after some iteration: */
                   2651:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2652:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2653:   /*  0,                   0                  , 1} */
                   2654:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2655:   /* {0.51571254859325999, 0.4842874514067399, */
                   2656:   /*  0.51326036147820708, 0.48673963852179264} */
                   2657:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2658: 
                   2659:   int i, ii,j,k;
1.247     brouard  2660:   int first=0;
1.217     brouard  2661:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2662:   /* double **matprod2(); */ /* test */
                   2663:   double **out, cov[NCOVMAX+1], **bmij();
                   2664:   double **newm;
1.218     brouard  2665:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2666:   double        **oldm, **savm;  /* for use */
                   2667: 
1.217     brouard  2668:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2669:   int ncvloop=0;
                   2670:   
                   2671:   min=vector(1,nlstate);
                   2672:   max=vector(1,nlstate);
                   2673:   meandiff=vector(1,nlstate);
                   2674: 
1.266     brouard  2675:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2676:   oldm=oldms; savm=savms;
                   2677:   
                   2678:   /* Starting with matrix unity */
                   2679:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2680:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2681:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2682:     }
                   2683:   
                   2684:   cov[1]=1.;
                   2685:   
                   2686:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2687:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2688:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2689:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2690:     ncvloop++;
1.218     brouard  2691:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2692:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2693:     /* Covariates have to be included here again */
                   2694:     cov[2]=agefin;
                   2695:     if(nagesqr==1)
                   2696:       cov[3]= agefin*agefin;;
1.242     brouard  2697:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2698:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2699:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2700:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2701:     }
                   2702:     /* for (k=1; k<=cptcovn;k++) { */
                   2703:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2704:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2705:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2706:     /* } */
                   2707:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2708:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2709:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2710:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2711:     }
                   2712:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2713:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2714:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2715:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2716:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2717:       if(Dummy[Tvar[Tage[k]]]){
                   2718:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2719:       } else{
                   2720:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2721:       }
                   2722:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2723:     }
                   2724:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2725:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2726:       if(Dummy[Tvard[k][1]==0]){
                   2727:        if(Dummy[Tvard[k][2]==0]){
                   2728:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2729:        }else{
                   2730:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2731:        }
                   2732:       }else{
                   2733:        if(Dummy[Tvard[k][2]==0]){
                   2734:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2735:        }else{
                   2736:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2737:        }
                   2738:       }
1.217     brouard  2739:     }
                   2740:     
                   2741:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2742:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2743:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2744:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2745:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2746:                /* ij should be linked to the correct index of cov */
                   2747:                /* age and covariate values ij are in 'cov', but we need to pass
                   2748:                 * ij for the observed prevalence at age and status and covariate
                   2749:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2750:                 */
                   2751:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2752:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2753:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2754:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2755:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2756:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2757:     /*         printf("%d newm= ",i); */
                   2758:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2759:     /*           printf("%f ",newm[i][j]); */
                   2760:     /*         } */
                   2761:     /*         printf("oldm * "); */
                   2762:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2763:     /*           printf("%f ",oldm[i][j]); */
                   2764:     /*         } */
1.268     brouard  2765:     /*         printf(" bmmij "); */
1.266     brouard  2766:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2767:     /*           printf("%f ",pmmij[i][j]); */
                   2768:     /*         } */
                   2769:     /*         printf("\n"); */
                   2770:     /*   } */
                   2771:     /* } */
1.217     brouard  2772:     savm=oldm;
                   2773:     oldm=newm;
1.266     brouard  2774: 
1.217     brouard  2775:     for(j=1; j<=nlstate; j++){
                   2776:       max[j]=0.;
                   2777:       min[j]=1.;
                   2778:     }
                   2779:     for(j=1; j<=nlstate; j++){ 
                   2780:       for(i=1;i<=nlstate;i++){
1.234     brouard  2781:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2782:        bprlim[i][j]= newm[i][j];
                   2783:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2784:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2785:       }
                   2786:     }
1.218     brouard  2787:                
1.217     brouard  2788:     maxmax=0.;
                   2789:     for(i=1; i<=nlstate; i++){
                   2790:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2791:       maxmax=FMAX(maxmax,meandiff[i]);
                   2792:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2793:     } /* i loop */
1.217     brouard  2794:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2795:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2796:     if(maxmax < ftolpl){
1.220     brouard  2797:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2798:       free_vector(min,1,nlstate);
                   2799:       free_vector(max,1,nlstate);
                   2800:       free_vector(meandiff,1,nlstate);
                   2801:       return bprlim;
                   2802:     }
                   2803:   } /* age loop */
                   2804:     /* After some age loop it doesn't converge */
1.247     brouard  2805:   if(first){
                   2806:     first=1;
                   2807:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2808: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2809:   }
                   2810:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2811: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2812:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2813:   free_vector(min,1,nlstate);
                   2814:   free_vector(max,1,nlstate);
                   2815:   free_vector(meandiff,1,nlstate);
                   2816:   
                   2817:   return bprlim; /* should not reach here */
                   2818: }
                   2819: 
1.126     brouard  2820: /*************** transition probabilities ***************/ 
                   2821: 
                   2822: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2823: {
1.138     brouard  2824:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2825:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2826:      model to the ncovmodel covariates (including constant and age).
                   2827:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2828:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2829:      ncth covariate in the global vector x is given by the formula:
                   2830:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2831:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2832:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2833:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2834:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2835:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2836:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2837:   */
                   2838:   double s1, lnpijopii;
1.126     brouard  2839:   /*double t34;*/
1.164     brouard  2840:   int i,j, nc, ii, jj;
1.126     brouard  2841: 
1.223     brouard  2842:   for(i=1; i<= nlstate; i++){
                   2843:     for(j=1; j<i;j++){
                   2844:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2845:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2846:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2847:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2848:       }
                   2849:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2850:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2851:     }
                   2852:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2853:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2854:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2855:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2856:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2857:       }
                   2858:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2859:     }
                   2860:   }
1.218     brouard  2861:   
1.223     brouard  2862:   for(i=1; i<= nlstate; i++){
                   2863:     s1=0;
                   2864:     for(j=1; j<i; j++){
                   2865:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2866:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2867:     }
                   2868:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2869:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2870:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2871:     }
                   2872:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2873:     ps[i][i]=1./(s1+1.);
                   2874:     /* Computing other pijs */
                   2875:     for(j=1; j<i; j++)
                   2876:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2877:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2878:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2879:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2880:   } /* end i */
1.218     brouard  2881:   
1.223     brouard  2882:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2883:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2884:       ps[ii][jj]=0;
                   2885:       ps[ii][ii]=1;
                   2886:     }
                   2887:   }
1.218     brouard  2888:   
                   2889:   
1.223     brouard  2890:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2891:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2892:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2893:   /*   } */
                   2894:   /*   printf("\n "); */
                   2895:   /* } */
                   2896:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2897:   /*
                   2898:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2899:                goto end;*/
1.266     brouard  2900:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2901: }
                   2902: 
1.218     brouard  2903: /*************** backward transition probabilities ***************/ 
                   2904: 
                   2905:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2906: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2907:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2908: {
1.266     brouard  2909:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2910:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2911:    */
1.218     brouard  2912:   int i, ii, j,k;
1.222     brouard  2913:   
                   2914:   double **out, **pmij();
                   2915:   double sumnew=0.;
1.218     brouard  2916:   double agefin;
1.268     brouard  2917:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2918:   double **dnewm, **dsavm, **doldm;
                   2919:   double **bbmij;
                   2920:   
1.218     brouard  2921:   doldm=ddoldms; /* global pointers */
1.222     brouard  2922:   dnewm=ddnewms;
                   2923:   dsavm=ddsavms;
                   2924:   
                   2925:   agefin=cov[2];
1.268     brouard  2926:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2927:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2928:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2929:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2930: 
                   2931:   /* P_x */
1.266     brouard  2932:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2933:   /* outputs pmmij which is a stochastic matrix in row */
                   2934: 
                   2935:   /* Diag(w_x) */
                   2936:   /* Problem with prevacurrent which can be zero */
                   2937:   sumnew=0.;
1.269     brouard  2938:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2939:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2940:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2941:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2942:   }
                   2943:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2944:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2945:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2946:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2947:     }
                   2948:   }else{
                   2949:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2950:       for (j=1;j<=nlstate+ndeath;j++)
                   2951:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2952:     }
                   2953:     /* if(sumnew <0.9){ */
                   2954:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2955:     /* } */
                   2956:   }
                   2957:   k3=0.0;  /* We put the last diagonal to 0 */
                   2958:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2959:       doldm[ii][ii]= k3;
                   2960:   }
                   2961:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2962:   
                   2963:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2964:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2965: 
                   2966:   /* Diag(Sum_i w^i_x p^ij_x */
                   2967:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2968:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2969:     sumnew=0.;
1.222     brouard  2970:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2971:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2972:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2973:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2974:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2975:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2976:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2977:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2978:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2979:        /* }else */
1.268     brouard  2980:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2981:     } /*End ii */
                   2982:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2983: 
                   2984:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2985:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2986:   /* end bmij */
1.266     brouard  2987:   return ps; /*pointer is unchanged */
1.218     brouard  2988: }
1.217     brouard  2989: /*************** transition probabilities ***************/ 
                   2990: 
1.218     brouard  2991: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2992: {
                   2993:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2994:      computes the probability to be observed in state j being in state i by appying the
                   2995:      model to the ncovmodel covariates (including constant and age).
                   2996:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2997:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2998:      ncth covariate in the global vector x is given by the formula:
                   2999:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3000:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3001:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3002:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3003:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3004:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3005:   */
                   3006:   double s1, lnpijopii;
                   3007:   /*double t34;*/
                   3008:   int i,j, nc, ii, jj;
                   3009: 
1.234     brouard  3010:   for(i=1; i<= nlstate; i++){
                   3011:     for(j=1; j<i;j++){
                   3012:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3013:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3014:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3015:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3016:       }
                   3017:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3018:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3019:     }
                   3020:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3021:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3022:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3023:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3024:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3025:       }
                   3026:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3027:     }
                   3028:   }
                   3029:   
                   3030:   for(i=1; i<= nlstate; i++){
                   3031:     s1=0;
                   3032:     for(j=1; j<i; j++){
                   3033:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3034:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3035:     }
                   3036:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3037:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3038:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3039:     }
                   3040:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3041:     ps[i][i]=1./(s1+1.);
                   3042:     /* Computing other pijs */
                   3043:     for(j=1; j<i; j++)
                   3044:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3045:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3046:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3047:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3048:   } /* end i */
                   3049:   
                   3050:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3051:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3052:       ps[ii][jj]=0;
                   3053:       ps[ii][ii]=1;
                   3054:     }
                   3055:   }
                   3056:   /* Added for backcast */ /* Transposed matrix too */
                   3057:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3058:     s1=0.;
                   3059:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3060:       s1+=ps[ii][jj];
                   3061:     }
                   3062:     for(ii=1; ii<= nlstate; ii++){
                   3063:       ps[ii][jj]=ps[ii][jj]/s1;
                   3064:     }
                   3065:   }
                   3066:   /* Transposition */
                   3067:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3068:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3069:       s1=ps[ii][jj];
                   3070:       ps[ii][jj]=ps[jj][ii];
                   3071:       ps[jj][ii]=s1;
                   3072:     }
                   3073:   }
                   3074:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3075:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3076:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3077:   /*   } */
                   3078:   /*   printf("\n "); */
                   3079:   /* } */
                   3080:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3081:   /*
                   3082:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3083:     goto end;*/
                   3084:   return ps;
1.217     brouard  3085: }
                   3086: 
                   3087: 
1.126     brouard  3088: /**************** Product of 2 matrices ******************/
                   3089: 
1.145     brouard  3090: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3091: {
                   3092:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3093:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3094:   /* in, b, out are matrice of pointers which should have been initialized 
                   3095:      before: only the contents of out is modified. The function returns
                   3096:      a pointer to pointers identical to out */
1.145     brouard  3097:   int i, j, k;
1.126     brouard  3098:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3099:     for(k=ncolol; k<=ncoloh; k++){
                   3100:       out[i][k]=0.;
                   3101:       for(j=ncl; j<=nch; j++)
                   3102:        out[i][k] +=in[i][j]*b[j][k];
                   3103:     }
1.126     brouard  3104:   return out;
                   3105: }
                   3106: 
                   3107: 
                   3108: /************* Higher Matrix Product ***************/
                   3109: 
1.235     brouard  3110: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3111: {
1.218     brouard  3112:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3113:      'nhstepm*hstepm*stepm' months (i.e. until
                   3114:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3115:      nhstepm*hstepm matrices. 
                   3116:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3117:      (typically every 2 years instead of every month which is too big 
                   3118:      for the memory).
                   3119:      Model is determined by parameters x and covariates have to be 
                   3120:      included manually here. 
                   3121: 
                   3122:      */
                   3123: 
                   3124:   int i, j, d, h, k;
1.131     brouard  3125:   double **out, cov[NCOVMAX+1];
1.126     brouard  3126:   double **newm;
1.187     brouard  3127:   double agexact;
1.214     brouard  3128:   double agebegin, ageend;
1.126     brouard  3129: 
                   3130:   /* Hstepm could be zero and should return the unit matrix */
                   3131:   for (i=1;i<=nlstate+ndeath;i++)
                   3132:     for (j=1;j<=nlstate+ndeath;j++){
                   3133:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3134:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3135:     }
                   3136:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3137:   for(h=1; h <=nhstepm; h++){
                   3138:     for(d=1; d <=hstepm; d++){
                   3139:       newm=savm;
                   3140:       /* Covariates have to be included here again */
                   3141:       cov[1]=1.;
1.214     brouard  3142:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3143:       cov[2]=agexact;
                   3144:       if(nagesqr==1)
1.227     brouard  3145:        cov[3]= agexact*agexact;
1.235     brouard  3146:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3147:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3148:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3149:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3150:       }
                   3151:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3152:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3153:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3154:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3155:       }
                   3156:       for (k=1; k<=cptcovage;k++){
                   3157:        if(Dummy[Tvar[Tage[k]]]){
                   3158:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3159:        } else{
                   3160:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3161:        }
                   3162:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3163:       }
                   3164:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3165:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3166:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3167:       }
                   3168:       /* for (k=1; k<=cptcovn;k++)  */
                   3169:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3170:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3171:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3172:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3173:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3174:       
                   3175:       
1.126     brouard  3176:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3177:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3178:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3179:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3180:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3181:       /* if((int)age == 70){ */
                   3182:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3183:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3184:       /*         printf("%d pmmij ",i); */
                   3185:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3186:       /*           printf("%f ",pmmij[i][j]); */
                   3187:       /*         } */
                   3188:       /*         printf(" oldm "); */
                   3189:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3190:       /*           printf("%f ",oldm[i][j]); */
                   3191:       /*         } */
                   3192:       /*         printf("\n"); */
                   3193:       /*       } */
                   3194:       /* } */
1.126     brouard  3195:       savm=oldm;
                   3196:       oldm=newm;
                   3197:     }
                   3198:     for(i=1; i<=nlstate+ndeath; i++)
                   3199:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3200:        po[i][j][h]=newm[i][j];
                   3201:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3202:       }
1.128     brouard  3203:     /*printf("h=%d ",h);*/
1.126     brouard  3204:   } /* end h */
1.267     brouard  3205:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3206:   return po;
                   3207: }
                   3208: 
1.217     brouard  3209: /************* Higher Back Matrix Product ***************/
1.218     brouard  3210: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3211: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3212: {
1.266     brouard  3213:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3214:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3215:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3216:      nhstepm*hstepm matrices.
                   3217:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3218:      (typically every 2 years instead of every month which is too big
1.217     brouard  3219:      for the memory).
1.218     brouard  3220:      Model is determined by parameters x and covariates have to be
1.266     brouard  3221:      included manually here. Then we use a call to bmij(x and cov)
                   3222:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3223:   */
1.217     brouard  3224: 
                   3225:   int i, j, d, h, k;
1.266     brouard  3226:   double **out, cov[NCOVMAX+1], **bmij();
                   3227:   double **newm, ***newmm;
1.217     brouard  3228:   double agexact;
                   3229:   double agebegin, ageend;
1.222     brouard  3230:   double **oldm, **savm;
1.217     brouard  3231: 
1.266     brouard  3232:   newmm=po; /* To be saved */
                   3233:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3234:   /* Hstepm could be zero and should return the unit matrix */
                   3235:   for (i=1;i<=nlstate+ndeath;i++)
                   3236:     for (j=1;j<=nlstate+ndeath;j++){
                   3237:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3238:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3239:     }
                   3240:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3241:   for(h=1; h <=nhstepm; h++){
                   3242:     for(d=1; d <=hstepm; d++){
                   3243:       newm=savm;
                   3244:       /* Covariates have to be included here again */
                   3245:       cov[1]=1.;
1.271   ! brouard  3246:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3247:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3248:       cov[2]=agexact;
                   3249:       if(nagesqr==1)
1.222     brouard  3250:        cov[3]= agexact*agexact;
1.266     brouard  3251:       for (k=1; k<=cptcovn;k++){
                   3252:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3253:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3254:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3255:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3256:       }
1.267     brouard  3257:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3258:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3259:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3260:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3261:       }
                   3262:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3263:        if(Dummy[Tvar[Tage[k]]]){
                   3264:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3265:        } else{
                   3266:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3267:        }
                   3268:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3269:       }
                   3270:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3271:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3272:       }                        
1.217     brouard  3273:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3274:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3275: 
1.218     brouard  3276:       /* Careful transposed matrix */
1.266     brouard  3277:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3278:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3279:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3280:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3281:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3282:       /* if((int)age == 70){ */
                   3283:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3284:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3285:       /*         printf("%d pmmij ",i); */
                   3286:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3287:       /*           printf("%f ",pmmij[i][j]); */
                   3288:       /*         } */
                   3289:       /*         printf(" oldm "); */
                   3290:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3291:       /*           printf("%f ",oldm[i][j]); */
                   3292:       /*         } */
                   3293:       /*         printf("\n"); */
                   3294:       /*       } */
                   3295:       /* } */
                   3296:       savm=oldm;
                   3297:       oldm=newm;
                   3298:     }
                   3299:     for(i=1; i<=nlstate+ndeath; i++)
                   3300:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3301:        po[i][j][h]=newm[i][j];
1.268     brouard  3302:        /* if(h==nhstepm) */
                   3303:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3304:       }
1.268     brouard  3305:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3306:   } /* end h */
1.268     brouard  3307:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3308:   return po;
                   3309: }
                   3310: 
                   3311: 
1.162     brouard  3312: #ifdef NLOPT
                   3313:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3314:   double fret;
                   3315:   double *xt;
                   3316:   int j;
                   3317:   myfunc_data *d2 = (myfunc_data *) pd;
                   3318: /* xt = (p1-1); */
                   3319:   xt=vector(1,n); 
                   3320:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3321: 
                   3322:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3323:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3324:   printf("Function = %.12lf ",fret);
                   3325:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3326:   printf("\n");
                   3327:  free_vector(xt,1,n);
                   3328:   return fret;
                   3329: }
                   3330: #endif
1.126     brouard  3331: 
                   3332: /*************** log-likelihood *************/
                   3333: double func( double *x)
                   3334: {
1.226     brouard  3335:   int i, ii, j, k, mi, d, kk;
                   3336:   int ioffset=0;
                   3337:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3338:   double **out;
                   3339:   double lli; /* Individual log likelihood */
                   3340:   int s1, s2;
1.228     brouard  3341:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3342:   double bbh, survp;
                   3343:   long ipmx;
                   3344:   double agexact;
                   3345:   /*extern weight */
                   3346:   /* We are differentiating ll according to initial status */
                   3347:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3348:   /*for(i=1;i<imx;i++) 
                   3349:     printf(" %d\n",s[4][i]);
                   3350:   */
1.162     brouard  3351: 
1.226     brouard  3352:   ++countcallfunc;
1.162     brouard  3353: 
1.226     brouard  3354:   cov[1]=1.;
1.126     brouard  3355: 
1.226     brouard  3356:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3357:   ioffset=0;
1.226     brouard  3358:   if(mle==1){
                   3359:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3360:       /* Computes the values of the ncovmodel covariates of the model
                   3361:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3362:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3363:         to be observed in j being in i according to the model.
                   3364:       */
1.243     brouard  3365:       ioffset=2+nagesqr ;
1.233     brouard  3366:    /* Fixed */
1.234     brouard  3367:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3368:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3369:       }
1.226     brouard  3370:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3371:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3372:         has been calculated etc */
                   3373:       /* For an individual i, wav[i] gives the number of effective waves */
                   3374:       /* We compute the contribution to Likelihood of each effective transition
                   3375:         mw[mi][i] is real wave of the mi th effectve wave */
                   3376:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3377:         s2=s[mw[mi+1][i]][i];
                   3378:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3379:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3380:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3381:       */
                   3382:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3383:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3384:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3385:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3386:        }
                   3387:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3388:          for (j=1;j<=nlstate+ndeath;j++){
                   3389:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3390:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3391:          }
                   3392:        for(d=0; d<dh[mi][i]; d++){
                   3393:          newm=savm;
                   3394:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3395:          cov[2]=agexact;
                   3396:          if(nagesqr==1)
                   3397:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3398:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3399:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3400:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3401:          else
                   3402:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3403:          }
                   3404:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3405:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3406:          savm=oldm;
                   3407:          oldm=newm;
                   3408:        } /* end mult */
                   3409:        
                   3410:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3411:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3412:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3413:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3414:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3415:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3416:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3417:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3418:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3419:                                 * -stepm/2 to stepm/2 .
                   3420:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3421:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3422:                                 */
1.234     brouard  3423:        s1=s[mw[mi][i]][i];
                   3424:        s2=s[mw[mi+1][i]][i];
                   3425:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3426:        /* bias bh is positive if real duration
                   3427:         * is higher than the multiple of stepm and negative otherwise.
                   3428:         */
                   3429:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3430:        if( s2 > nlstate){ 
                   3431:          /* i.e. if s2 is a death state and if the date of death is known 
                   3432:             then the contribution to the likelihood is the probability to 
                   3433:             die between last step unit time and current  step unit time, 
                   3434:             which is also equal to probability to die before dh 
                   3435:             minus probability to die before dh-stepm . 
                   3436:             In version up to 0.92 likelihood was computed
                   3437:             as if date of death was unknown. Death was treated as any other
                   3438:             health state: the date of the interview describes the actual state
                   3439:             and not the date of a change in health state. The former idea was
                   3440:             to consider that at each interview the state was recorded
                   3441:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3442:             introduced the exact date of death then we should have modified
                   3443:             the contribution of an exact death to the likelihood. This new
                   3444:             contribution is smaller and very dependent of the step unit
                   3445:             stepm. It is no more the probability to die between last interview
                   3446:             and month of death but the probability to survive from last
                   3447:             interview up to one month before death multiplied by the
                   3448:             probability to die within a month. Thanks to Chris
                   3449:             Jackson for correcting this bug.  Former versions increased
                   3450:             mortality artificially. The bad side is that we add another loop
                   3451:             which slows down the processing. The difference can be up to 10%
                   3452:             lower mortality.
                   3453:          */
                   3454:          /* If, at the beginning of the maximization mostly, the
                   3455:             cumulative probability or probability to be dead is
                   3456:             constant (ie = 1) over time d, the difference is equal to
                   3457:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3458:             s1 at precedent wave, to be dead a month before current
                   3459:             wave is equal to probability, being at state s1 at
                   3460:             precedent wave, to be dead at mont of the current
                   3461:             wave. Then the observed probability (that this person died)
                   3462:             is null according to current estimated parameter. In fact,
                   3463:             it should be very low but not zero otherwise the log go to
                   3464:             infinity.
                   3465:          */
1.183     brouard  3466: /* #ifdef INFINITYORIGINAL */
                   3467: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3468: /* #else */
                   3469: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3470: /*         lli=log(mytinydouble); */
                   3471: /*       else */
                   3472: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3473: /* #endif */
1.226     brouard  3474:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3475:          
1.226     brouard  3476:        } else if  ( s2==-1 ) { /* alive */
                   3477:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3478:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3479:          /*survp += out[s1][j]; */
                   3480:          lli= log(survp);
                   3481:        }
                   3482:        else if  (s2==-4) { 
                   3483:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3484:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3485:          lli= log(survp); 
                   3486:        } 
                   3487:        else if  (s2==-5) { 
                   3488:          for (j=1,survp=0. ; j<=2; j++)  
                   3489:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3490:          lli= log(survp); 
                   3491:        } 
                   3492:        else{
                   3493:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3494:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3495:        } 
                   3496:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3497:        /*if(lli ==000.0)*/
                   3498:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3499:        ipmx +=1;
                   3500:        sw += weight[i];
                   3501:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3502:        /* if (lli < log(mytinydouble)){ */
                   3503:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3504:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3505:        /* } */
                   3506:       } /* end of wave */
                   3507:     } /* end of individual */
                   3508:   }  else if(mle==2){
                   3509:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3510:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3511:       for(mi=1; mi<= wav[i]-1; mi++){
                   3512:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3513:          for (j=1;j<=nlstate+ndeath;j++){
                   3514:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3515:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3516:          }
                   3517:        for(d=0; d<=dh[mi][i]; d++){
                   3518:          newm=savm;
                   3519:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3520:          cov[2]=agexact;
                   3521:          if(nagesqr==1)
                   3522:            cov[3]= agexact*agexact;
                   3523:          for (kk=1; kk<=cptcovage;kk++) {
                   3524:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3525:          }
                   3526:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3527:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3528:          savm=oldm;
                   3529:          oldm=newm;
                   3530:        } /* end mult */
                   3531:       
                   3532:        s1=s[mw[mi][i]][i];
                   3533:        s2=s[mw[mi+1][i]][i];
                   3534:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3535:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3536:        ipmx +=1;
                   3537:        sw += weight[i];
                   3538:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3539:       } /* end of wave */
                   3540:     } /* end of individual */
                   3541:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3542:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3543:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3544:       for(mi=1; mi<= wav[i]-1; mi++){
                   3545:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3546:          for (j=1;j<=nlstate+ndeath;j++){
                   3547:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3548:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3549:          }
                   3550:        for(d=0; d<dh[mi][i]; d++){
                   3551:          newm=savm;
                   3552:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3553:          cov[2]=agexact;
                   3554:          if(nagesqr==1)
                   3555:            cov[3]= agexact*agexact;
                   3556:          for (kk=1; kk<=cptcovage;kk++) {
                   3557:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3558:          }
                   3559:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3560:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3561:          savm=oldm;
                   3562:          oldm=newm;
                   3563:        } /* end mult */
                   3564:       
                   3565:        s1=s[mw[mi][i]][i];
                   3566:        s2=s[mw[mi+1][i]][i];
                   3567:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3568:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3569:        ipmx +=1;
                   3570:        sw += weight[i];
                   3571:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3572:       } /* end of wave */
                   3573:     } /* end of individual */
                   3574:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3575:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3576:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3577:       for(mi=1; mi<= wav[i]-1; mi++){
                   3578:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3579:          for (j=1;j<=nlstate+ndeath;j++){
                   3580:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3581:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3582:          }
                   3583:        for(d=0; d<dh[mi][i]; d++){
                   3584:          newm=savm;
                   3585:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3586:          cov[2]=agexact;
                   3587:          if(nagesqr==1)
                   3588:            cov[3]= agexact*agexact;
                   3589:          for (kk=1; kk<=cptcovage;kk++) {
                   3590:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3591:          }
1.126     brouard  3592:        
1.226     brouard  3593:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3594:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3595:          savm=oldm;
                   3596:          oldm=newm;
                   3597:        } /* end mult */
                   3598:       
                   3599:        s1=s[mw[mi][i]][i];
                   3600:        s2=s[mw[mi+1][i]][i];
                   3601:        if( s2 > nlstate){ 
                   3602:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3603:        } else if  ( s2==-1 ) { /* alive */
                   3604:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3605:            survp += out[s1][j];
                   3606:          lli= log(survp);
                   3607:        }else{
                   3608:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3609:        }
                   3610:        ipmx +=1;
                   3611:        sw += weight[i];
                   3612:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3613: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3614:       } /* end of wave */
                   3615:     } /* end of individual */
                   3616:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3617:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3618:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3619:       for(mi=1; mi<= wav[i]-1; mi++){
                   3620:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3621:          for (j=1;j<=nlstate+ndeath;j++){
                   3622:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3623:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3624:          }
                   3625:        for(d=0; d<dh[mi][i]; d++){
                   3626:          newm=savm;
                   3627:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3628:          cov[2]=agexact;
                   3629:          if(nagesqr==1)
                   3630:            cov[3]= agexact*agexact;
                   3631:          for (kk=1; kk<=cptcovage;kk++) {
                   3632:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3633:          }
1.126     brouard  3634:        
1.226     brouard  3635:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3636:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3637:          savm=oldm;
                   3638:          oldm=newm;
                   3639:        } /* end mult */
                   3640:       
                   3641:        s1=s[mw[mi][i]][i];
                   3642:        s2=s[mw[mi+1][i]][i];
                   3643:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3644:        ipmx +=1;
                   3645:        sw += weight[i];
                   3646:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3647:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3648:       } /* end of wave */
                   3649:     } /* end of individual */
                   3650:   } /* End of if */
                   3651:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3652:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3653:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3654:   return -l;
1.126     brouard  3655: }
                   3656: 
                   3657: /*************** log-likelihood *************/
                   3658: double funcone( double *x)
                   3659: {
1.228     brouard  3660:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3661:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3662:   int ioffset=0;
1.131     brouard  3663:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3664:   double **out;
                   3665:   double lli; /* Individual log likelihood */
                   3666:   double llt;
                   3667:   int s1, s2;
1.228     brouard  3668:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3669: 
1.126     brouard  3670:   double bbh, survp;
1.187     brouard  3671:   double agexact;
1.214     brouard  3672:   double agebegin, ageend;
1.126     brouard  3673:   /*extern weight */
                   3674:   /* We are differentiating ll according to initial status */
                   3675:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3676:   /*for(i=1;i<imx;i++) 
                   3677:     printf(" %d\n",s[4][i]);
                   3678:   */
                   3679:   cov[1]=1.;
                   3680: 
                   3681:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3682:   ioffset=0;
                   3683:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3684:     /* ioffset=2+nagesqr+cptcovage; */
                   3685:     ioffset=2+nagesqr;
1.232     brouard  3686:     /* Fixed */
1.224     brouard  3687:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3688:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3689:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3690:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3691: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3692: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3693: /*    cov[2+6]=covar[2][i]; V2  */
                   3694: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3695: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3696: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3697: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3698: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3699: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3700:     }
1.232     brouard  3701:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3702:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3703:     /* } */
1.231     brouard  3704:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3705:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3706:     /* } */
1.225     brouard  3707:     
1.233     brouard  3708: 
                   3709:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3710:     /* Wave varying (but not age varying) */
                   3711:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3712:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3713:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3714:       }
1.232     brouard  3715:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3716:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3717:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3718:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3719:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3720:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3721:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3722:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3723:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3724:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3725:       /* } */
1.126     brouard  3726:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3727:        for (j=1;j<=nlstate+ndeath;j++){
                   3728:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3729:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3730:        }
1.214     brouard  3731:       
                   3732:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3733:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3734:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3735:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3736:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3737:          and mw[mi+1][i]. dh depends on stepm.*/
                   3738:        newm=savm;
1.247     brouard  3739:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3740:        cov[2]=agexact;
                   3741:        if(nagesqr==1)
                   3742:          cov[3]= agexact*agexact;
                   3743:        for (kk=1; kk<=cptcovage;kk++) {
                   3744:          if(!FixedV[Tvar[Tage[kk]]])
                   3745:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3746:          else
                   3747:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3748:        }
                   3749:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3750:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3751:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3752:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3753:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3754:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3755:        savm=oldm;
                   3756:        oldm=newm;
1.126     brouard  3757:       } /* end mult */
                   3758:       
                   3759:       s1=s[mw[mi][i]][i];
                   3760:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3761:       /* if(s2==-1){ */
1.268     brouard  3762:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3763:       /*       /\* exit(1); *\/ */
                   3764:       /* } */
1.126     brouard  3765:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3766:       /* bias is positive if real duration
                   3767:        * is higher than the multiple of stepm and negative otherwise.
                   3768:        */
                   3769:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3770:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3771:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3772:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3773:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3774:        lli= log(survp);
1.126     brouard  3775:       }else if (mle==1){
1.242     brouard  3776:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3777:       } else if(mle==2){
1.242     brouard  3778:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3779:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3780:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3781:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3782:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3783:       } else{  /* mle=0 back to 1 */
1.242     brouard  3784:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3785:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3786:       } /* End of if */
                   3787:       ipmx +=1;
                   3788:       sw += weight[i];
                   3789:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3790:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3791:       if(globpr){
1.246     brouard  3792:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3793:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3794:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3795:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3796:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3797:          llt +=ll[k]*gipmx/gsw;
                   3798:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3799:        }
                   3800:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3801:       }
1.232     brouard  3802:        } /* end of wave */
                   3803: } /* end of individual */
                   3804: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3805: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3806: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3807: if(globpr==0){ /* First time we count the contributions and weights */
                   3808:        gipmx=ipmx;
                   3809:        gsw=sw;
                   3810: }
                   3811: return -l;
1.126     brouard  3812: }
                   3813: 
                   3814: 
                   3815: /*************** function likelione ***********/
                   3816: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3817: {
                   3818:   /* This routine should help understanding what is done with 
                   3819:      the selection of individuals/waves and
                   3820:      to check the exact contribution to the likelihood.
                   3821:      Plotting could be done.
                   3822:    */
                   3823:   int k;
                   3824: 
                   3825:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3826:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3827:     strcat(fileresilk,fileresu);
1.126     brouard  3828:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3829:       printf("Problem with resultfile: %s\n", fileresilk);
                   3830:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3831:     }
1.214     brouard  3832:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3833:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3834:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3835:     for(k=1; k<=nlstate; k++) 
                   3836:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3837:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3838:   }
                   3839: 
                   3840:   *fretone=(*funcone)(p);
                   3841:   if(*globpri !=0){
                   3842:     fclose(ficresilk);
1.205     brouard  3843:     if (mle ==0)
                   3844:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3845:     else if(mle >=1)
                   3846:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3847:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3848:     
1.208     brouard  3849:       
                   3850:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3851:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3852: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3853:     }
1.207     brouard  3854:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3855: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3856:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3857: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3858:     fflush(fichtm);
1.205     brouard  3859:   }
1.126     brouard  3860:   return;
                   3861: }
                   3862: 
                   3863: 
                   3864: /*********** Maximum Likelihood Estimation ***************/
                   3865: 
                   3866: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3867: {
1.165     brouard  3868:   int i,j, iter=0;
1.126     brouard  3869:   double **xi;
                   3870:   double fret;
                   3871:   double fretone; /* Only one call to likelihood */
                   3872:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3873: 
                   3874: #ifdef NLOPT
                   3875:   int creturn;
                   3876:   nlopt_opt opt;
                   3877:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3878:   double *lb;
                   3879:   double minf; /* the minimum objective value, upon return */
                   3880:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3881:   myfunc_data dinst, *d = &dinst;
                   3882: #endif
                   3883: 
                   3884: 
1.126     brouard  3885:   xi=matrix(1,npar,1,npar);
                   3886:   for (i=1;i<=npar;i++)
                   3887:     for (j=1;j<=npar;j++)
                   3888:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3889:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3890:   strcpy(filerespow,"POW_"); 
1.126     brouard  3891:   strcat(filerespow,fileres);
                   3892:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3893:     printf("Problem with resultfile: %s\n", filerespow);
                   3894:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3895:   }
                   3896:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3897:   for (i=1;i<=nlstate;i++)
                   3898:     for(j=1;j<=nlstate+ndeath;j++)
                   3899:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3900:   fprintf(ficrespow,"\n");
1.162     brouard  3901: #ifdef POWELL
1.126     brouard  3902:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3903: #endif
1.126     brouard  3904: 
1.162     brouard  3905: #ifdef NLOPT
                   3906: #ifdef NEWUOA
                   3907:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3908: #else
                   3909:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3910: #endif
                   3911:   lb=vector(0,npar-1);
                   3912:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3913:   nlopt_set_lower_bounds(opt, lb);
                   3914:   nlopt_set_initial_step1(opt, 0.1);
                   3915:   
                   3916:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3917:   d->function = func;
                   3918:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3919:   nlopt_set_min_objective(opt, myfunc, d);
                   3920:   nlopt_set_xtol_rel(opt, ftol);
                   3921:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3922:     printf("nlopt failed! %d\n",creturn); 
                   3923:   }
                   3924:   else {
                   3925:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3926:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3927:     iter=1; /* not equal */
                   3928:   }
                   3929:   nlopt_destroy(opt);
                   3930: #endif
1.126     brouard  3931:   free_matrix(xi,1,npar,1,npar);
                   3932:   fclose(ficrespow);
1.203     brouard  3933:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3934:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3935:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3936: 
                   3937: }
                   3938: 
                   3939: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3940: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3941: {
                   3942:   double  **a,**y,*x,pd;
1.203     brouard  3943:   /* double **hess; */
1.164     brouard  3944:   int i, j;
1.126     brouard  3945:   int *indx;
                   3946: 
                   3947:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3948:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3949:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3950:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3951:   double gompertz(double p[]);
1.203     brouard  3952:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3953: 
                   3954:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3955:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3956:   for (i=1;i<=npar;i++){
1.203     brouard  3957:     printf("%d-",i);fflush(stdout);
                   3958:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3959:    
                   3960:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3961:     
                   3962:     /*  printf(" %f ",p[i]);
                   3963:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3964:   }
                   3965:   
                   3966:   for (i=1;i<=npar;i++) {
                   3967:     for (j=1;j<=npar;j++)  {
                   3968:       if (j>i) { 
1.203     brouard  3969:        printf(".%d-%d",i,j);fflush(stdout);
                   3970:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3971:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3972:        
                   3973:        hess[j][i]=hess[i][j];    
                   3974:        /*printf(" %lf ",hess[i][j]);*/
                   3975:       }
                   3976:     }
                   3977:   }
                   3978:   printf("\n");
                   3979:   fprintf(ficlog,"\n");
                   3980: 
                   3981:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3982:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3983:   
                   3984:   a=matrix(1,npar,1,npar);
                   3985:   y=matrix(1,npar,1,npar);
                   3986:   x=vector(1,npar);
                   3987:   indx=ivector(1,npar);
                   3988:   for (i=1;i<=npar;i++)
                   3989:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3990:   ludcmp(a,npar,indx,&pd);
                   3991: 
                   3992:   for (j=1;j<=npar;j++) {
                   3993:     for (i=1;i<=npar;i++) x[i]=0;
                   3994:     x[j]=1;
                   3995:     lubksb(a,npar,indx,x);
                   3996:     for (i=1;i<=npar;i++){ 
                   3997:       matcov[i][j]=x[i];
                   3998:     }
                   3999:   }
                   4000: 
                   4001:   printf("\n#Hessian matrix#\n");
                   4002:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4003:   for (i=1;i<=npar;i++) { 
                   4004:     for (j=1;j<=npar;j++) { 
1.203     brouard  4005:       printf("%.6e ",hess[i][j]);
                   4006:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4007:     }
                   4008:     printf("\n");
                   4009:     fprintf(ficlog,"\n");
                   4010:   }
                   4011: 
1.203     brouard  4012:   /* printf("\n#Covariance matrix#\n"); */
                   4013:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4014:   /* for (i=1;i<=npar;i++) {  */
                   4015:   /*   for (j=1;j<=npar;j++) {  */
                   4016:   /*     printf("%.6e ",matcov[i][j]); */
                   4017:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4018:   /*   } */
                   4019:   /*   printf("\n"); */
                   4020:   /*   fprintf(ficlog,"\n"); */
                   4021:   /* } */
                   4022: 
1.126     brouard  4023:   /* Recompute Inverse */
1.203     brouard  4024:   /* for (i=1;i<=npar;i++) */
                   4025:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4026:   /* ludcmp(a,npar,indx,&pd); */
                   4027: 
                   4028:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4029: 
                   4030:   /* for (j=1;j<=npar;j++) { */
                   4031:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4032:   /*   x[j]=1; */
                   4033:   /*   lubksb(a,npar,indx,x); */
                   4034:   /*   for (i=1;i<=npar;i++){  */
                   4035:   /*     y[i][j]=x[i]; */
                   4036:   /*     printf("%.3e ",y[i][j]); */
                   4037:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4038:   /*   } */
                   4039:   /*   printf("\n"); */
                   4040:   /*   fprintf(ficlog,"\n"); */
                   4041:   /* } */
                   4042: 
                   4043:   /* Verifying the inverse matrix */
                   4044: #ifdef DEBUGHESS
                   4045:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4046: 
1.203     brouard  4047:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4048:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4049: 
                   4050:   for (j=1;j<=npar;j++) {
                   4051:     for (i=1;i<=npar;i++){ 
1.203     brouard  4052:       printf("%.2f ",y[i][j]);
                   4053:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4054:     }
                   4055:     printf("\n");
                   4056:     fprintf(ficlog,"\n");
                   4057:   }
1.203     brouard  4058: #endif
1.126     brouard  4059: 
                   4060:   free_matrix(a,1,npar,1,npar);
                   4061:   free_matrix(y,1,npar,1,npar);
                   4062:   free_vector(x,1,npar);
                   4063:   free_ivector(indx,1,npar);
1.203     brouard  4064:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4065: 
                   4066: 
                   4067: }
                   4068: 
                   4069: /*************** hessian matrix ****************/
                   4070: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4071: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4072:   int i;
                   4073:   int l=1, lmax=20;
1.203     brouard  4074:   double k1,k2, res, fx;
1.132     brouard  4075:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4076:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4077:   int k=0,kmax=10;
                   4078:   double l1;
                   4079: 
                   4080:   fx=func(x);
                   4081:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4082:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4083:     l1=pow(10,l);
                   4084:     delts=delt;
                   4085:     for(k=1 ; k <kmax; k=k+1){
                   4086:       delt = delta*(l1*k);
                   4087:       p2[theta]=x[theta] +delt;
1.145     brouard  4088:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4089:       p2[theta]=x[theta]-delt;
                   4090:       k2=func(p2)-fx;
                   4091:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4092:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4093:       
1.203     brouard  4094: #ifdef DEBUGHESSII
1.126     brouard  4095:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4096:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4097: #endif
                   4098:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4099:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4100:        k=kmax;
                   4101:       }
                   4102:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4103:        k=kmax; l=lmax*10;
1.126     brouard  4104:       }
                   4105:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4106:        delts=delt;
                   4107:       }
1.203     brouard  4108:     } /* End loop k */
1.126     brouard  4109:   }
                   4110:   delti[theta]=delts;
                   4111:   return res; 
                   4112:   
                   4113: }
                   4114: 
1.203     brouard  4115: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4116: {
                   4117:   int i;
1.164     brouard  4118:   int l=1, lmax=20;
1.126     brouard  4119:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4120:   double p2[MAXPARM+1];
1.203     brouard  4121:   int k, kmax=1;
                   4122:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4123: 
                   4124:   int firstime=0;
1.203     brouard  4125:   
1.126     brouard  4126:   fx=func(x);
1.203     brouard  4127:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4128:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4129:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4130:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4131:     k1=func(p2)-fx;
                   4132:   
1.203     brouard  4133:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4134:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4135:     k2=func(p2)-fx;
                   4136:   
1.203     brouard  4137:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4138:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4139:     k3=func(p2)-fx;
                   4140:   
1.203     brouard  4141:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4142:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4143:     k4=func(p2)-fx;
1.203     brouard  4144:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4145:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4146:       firstime=1;
1.203     brouard  4147:       kmax=kmax+10;
1.208     brouard  4148:     }
                   4149:     if(kmax >=10 || firstime ==1){
1.246     brouard  4150:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4151:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4152:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4153:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4154:     }
                   4155: #ifdef DEBUGHESSIJ
                   4156:     v1=hess[thetai][thetai];
                   4157:     v2=hess[thetaj][thetaj];
                   4158:     cv12=res;
                   4159:     /* Computing eigen value of Hessian matrix */
                   4160:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4161:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4162:     if ((lc2 <0) || (lc1 <0) ){
                   4163:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4164:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4165:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4166:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4167:     }
1.126     brouard  4168: #endif
                   4169:   }
                   4170:   return res;
                   4171: }
                   4172: 
1.203     brouard  4173:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4174: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4175: /* { */
                   4176: /*   int i; */
                   4177: /*   int l=1, lmax=20; */
                   4178: /*   double k1,k2,k3,k4,res,fx; */
                   4179: /*   double p2[MAXPARM+1]; */
                   4180: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4181: /*   int k=0,kmax=10; */
                   4182: /*   double l1; */
                   4183:   
                   4184: /*   fx=func(x); */
                   4185: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4186: /*     l1=pow(10,l); */
                   4187: /*     delts=delt; */
                   4188: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4189: /*       delt = delti*(l1*k); */
                   4190: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4191: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4192: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4193: /*       k1=func(p2)-fx; */
                   4194:       
                   4195: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4196: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4197: /*       k2=func(p2)-fx; */
                   4198:       
                   4199: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4200: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4201: /*       k3=func(p2)-fx; */
                   4202:       
                   4203: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4204: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4205: /*       k4=func(p2)-fx; */
                   4206: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4207: /* #ifdef DEBUGHESSIJ */
                   4208: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4209: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4210: /* #endif */
                   4211: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4212: /*     k=kmax; */
                   4213: /*       } */
                   4214: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4215: /*     k=kmax; l=lmax*10; */
                   4216: /*       } */
                   4217: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4218: /*     delts=delt; */
                   4219: /*       } */
                   4220: /*     } /\* End loop k *\/ */
                   4221: /*   } */
                   4222: /*   delti[theta]=delts; */
                   4223: /*   return res;  */
                   4224: /* } */
                   4225: 
                   4226: 
1.126     brouard  4227: /************** Inverse of matrix **************/
                   4228: void ludcmp(double **a, int n, int *indx, double *d) 
                   4229: { 
                   4230:   int i,imax,j,k; 
                   4231:   double big,dum,sum,temp; 
                   4232:   double *vv; 
                   4233:  
                   4234:   vv=vector(1,n); 
                   4235:   *d=1.0; 
                   4236:   for (i=1;i<=n;i++) { 
                   4237:     big=0.0; 
                   4238:     for (j=1;j<=n;j++) 
                   4239:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4240:     if (big == 0.0){
                   4241:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4242:       for (j=1;j<=n;j++) {
                   4243:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4244:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4245:       }
                   4246:       fflush(ficlog);
                   4247:       fclose(ficlog);
                   4248:       nrerror("Singular matrix in routine ludcmp"); 
                   4249:     }
1.126     brouard  4250:     vv[i]=1.0/big; 
                   4251:   } 
                   4252:   for (j=1;j<=n;j++) { 
                   4253:     for (i=1;i<j;i++) { 
                   4254:       sum=a[i][j]; 
                   4255:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4256:       a[i][j]=sum; 
                   4257:     } 
                   4258:     big=0.0; 
                   4259:     for (i=j;i<=n;i++) { 
                   4260:       sum=a[i][j]; 
                   4261:       for (k=1;k<j;k++) 
                   4262:        sum -= a[i][k]*a[k][j]; 
                   4263:       a[i][j]=sum; 
                   4264:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4265:        big=dum; 
                   4266:        imax=i; 
                   4267:       } 
                   4268:     } 
                   4269:     if (j != imax) { 
                   4270:       for (k=1;k<=n;k++) { 
                   4271:        dum=a[imax][k]; 
                   4272:        a[imax][k]=a[j][k]; 
                   4273:        a[j][k]=dum; 
                   4274:       } 
                   4275:       *d = -(*d); 
                   4276:       vv[imax]=vv[j]; 
                   4277:     } 
                   4278:     indx[j]=imax; 
                   4279:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4280:     if (j != n) { 
                   4281:       dum=1.0/(a[j][j]); 
                   4282:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4283:     } 
                   4284:   } 
                   4285:   free_vector(vv,1,n);  /* Doesn't work */
                   4286: ;
                   4287: } 
                   4288: 
                   4289: void lubksb(double **a, int n, int *indx, double b[]) 
                   4290: { 
                   4291:   int i,ii=0,ip,j; 
                   4292:   double sum; 
                   4293:  
                   4294:   for (i=1;i<=n;i++) { 
                   4295:     ip=indx[i]; 
                   4296:     sum=b[ip]; 
                   4297:     b[ip]=b[i]; 
                   4298:     if (ii) 
                   4299:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4300:     else if (sum) ii=i; 
                   4301:     b[i]=sum; 
                   4302:   } 
                   4303:   for (i=n;i>=1;i--) { 
                   4304:     sum=b[i]; 
                   4305:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4306:     b[i]=sum/a[i][i]; 
                   4307:   } 
                   4308: } 
                   4309: 
                   4310: void pstamp(FILE *fichier)
                   4311: {
1.196     brouard  4312:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4313: }
                   4314: 
1.253     brouard  4315: 
                   4316: 
1.126     brouard  4317: /************ Frequencies ********************/
1.251     brouard  4318: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4319:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4320:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4321: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4322:   
1.265     brouard  4323:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4324:   int iind=0, iage=0;
                   4325:   int mi; /* Effective wave */
                   4326:   int first;
                   4327:   double ***freq; /* Frequencies */
1.268     brouard  4328:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4329:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4330:   double *meanq;
                   4331:   double **meanqt;
                   4332:   double *pp, **prop, *posprop, *pospropt;
                   4333:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4334:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4335:   double agebegin, ageend;
                   4336:     
                   4337:   pp=vector(1,nlstate);
1.251     brouard  4338:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4339:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4340:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4341:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4342:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4343:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4344:   strcpy(fileresp,"P_");
                   4345:   strcat(fileresp,fileresu);
                   4346:   /*strcat(fileresphtm,fileresu);*/
                   4347:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4348:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4349:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4350:     exit(0);
                   4351:   }
1.240     brouard  4352:   
1.226     brouard  4353:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4354:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4355:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4356:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4357:     fflush(ficlog);
                   4358:     exit(70); 
                   4359:   }
                   4360:   else{
                   4361:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4362: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4363: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4364:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4365:   }
1.237     brouard  4366:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4367:   
1.226     brouard  4368:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4369:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4370:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4371:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4372:     fflush(ficlog);
                   4373:     exit(70); 
1.240     brouard  4374:   } else{
1.226     brouard  4375:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4376: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4377: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4378:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4379:   }
1.240     brouard  4380:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4381:   
1.253     brouard  4382:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4383:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4384:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4385:   j1=0;
1.126     brouard  4386:   
1.227     brouard  4387:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4388:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4389:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4390:   
                   4391:   
1.226     brouard  4392:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4393:      reference=low_education V1=0,V2=0
                   4394:      med_educ                V1=1 V2=0, 
                   4395:      high_educ               V1=0 V2=1
                   4396:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4397:   */
1.249     brouard  4398:   dateintsum=0;
                   4399:   k2cpt=0;
                   4400: 
1.253     brouard  4401:   if(cptcoveff == 0 )
1.265     brouard  4402:     nl=1;  /* Constant and age model only */
1.253     brouard  4403:   else
                   4404:     nl=2;
1.265     brouard  4405: 
                   4406:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4407:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4408:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4409:    *     freq[s1][s2][iage] =0.
                   4410:    *     Loop on iind
                   4411:    *       ++freq[s1][s2][iage] weighted
                   4412:    *     end iind
                   4413:    *     if covariate and j!0
                   4414:    *       headers Variable on one line
                   4415:    *     endif cov j!=0
                   4416:    *     header of frequency table by age
                   4417:    *     Loop on age
                   4418:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4419:    *       pos+=freq[s1][s2][iage] weighted
                   4420:    *       Loop on s1 initial state
                   4421:    *         fprintf(ficresp
                   4422:    *       end s1
                   4423:    *     end age
                   4424:    *     if j!=0 computes starting values
                   4425:    *     end compute starting values
                   4426:    *   end j1
                   4427:    * end nl 
                   4428:    */
1.253     brouard  4429:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4430:     if(nj==1)
                   4431:       j=0;  /* First pass for the constant */
1.265     brouard  4432:     else{
1.253     brouard  4433:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4434:     }
1.251     brouard  4435:     first=1;
1.265     brouard  4436:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4437:       posproptt=0.;
                   4438:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4439:        scanf("%d", i);*/
                   4440:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4441:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4442:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4443:            freq[i][s2][m]=0;
1.251     brouard  4444:       
                   4445:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4446:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4447:          prop[i][m]=0;
                   4448:        posprop[i]=0;
                   4449:        pospropt[i]=0;
                   4450:       }
                   4451:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4452:       /*   meanq[z1]+=0.; */
                   4453:       /*   for(m=1;m<=lastpass;m++){ */
                   4454:       /*       meanqt[m][z1]=0.; */
                   4455:       /*   } */
                   4456:       /* } */
                   4457:       
                   4458:       /* dateintsum=0; */
                   4459:       /* k2cpt=0; */
                   4460:       
1.265     brouard  4461:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4462:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4463:        bool=1;
                   4464:        if(j !=0){
                   4465:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4466:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4467:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4468:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4469:              /* } */
                   4470:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4471:                /* if(Tvaraff[z1] ==-20){ */
                   4472:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4473:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4474:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4475:                /* }else  */
                   4476:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4477:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4478:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4479:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4480:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4481:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4482:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4483:                } /* Onlyf fixed */
                   4484:              } /* end z1 */
                   4485:            } /* cptcovn > 0 */
                   4486:          } /* end any */
                   4487:        }/* end j==0 */
1.265     brouard  4488:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4489:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4490:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4491:            m=mw[mi][iind];
                   4492:            if(j!=0){
                   4493:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4494:                for (z1=1; z1<=cptcoveff; z1++) {
                   4495:                  if( Fixed[Tmodelind[z1]]==1){
                   4496:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4497:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4498:                                                                                      value is -1, we don't select. It differs from the 
                   4499:                                                                                      constant and age model which counts them. */
                   4500:                      bool=0; /* not selected */
                   4501:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4502:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4503:                      bool=0;
                   4504:                    }
                   4505:                  }
                   4506:                }
                   4507:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4508:            } /* end j==0 */
                   4509:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4510:            if(bool==1){
                   4511:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4512:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4513:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4514:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4515:              if(m >=firstpass && m <=lastpass){
                   4516:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4517:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4518:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4519:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4520:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4521:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4522:                if (m<lastpass) {
                   4523:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4524:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4525:                  if(s[m][iind]==-1)
                   4526:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4527:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4528:                  /* if((int)agev[m][iind] == 55) */
                   4529:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4530:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4531:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4532:                }
1.251     brouard  4533:              } /* end if between passes */  
                   4534:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4535:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4536:                k2cpt++;
                   4537:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4538:              }
1.251     brouard  4539:            }else{
                   4540:              bool=1;
                   4541:            }/* end bool 2 */
                   4542:          } /* end m */
                   4543:        } /* end bool */
                   4544:       } /* end iind = 1 to imx */
                   4545:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4546:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4547:       
                   4548:       
                   4549:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4550:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4551:         pstamp(ficresp);
1.251     brouard  4552:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4553:         pstamp(ficresp);
1.251     brouard  4554:        printf( "\n#********** Variable "); 
                   4555:        fprintf(ficresp, "\n#********** Variable "); 
                   4556:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4557:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4558:        fprintf(ficlog, "\n#********** Variable "); 
                   4559:        for (z1=1; z1<=cptcoveff; z1++){
                   4560:          if(!FixedV[Tvaraff[z1]]){
                   4561:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4562:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4563:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4564:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4565:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4566:          }else{
1.251     brouard  4567:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4568:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4569:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4570:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4571:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4572:          }
                   4573:        }
                   4574:        printf( "**********\n#");
                   4575:        fprintf(ficresp, "**********\n#");
                   4576:        fprintf(ficresphtm, "**********</h3>\n");
                   4577:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4578:        fprintf(ficlog, "**********\n");
                   4579:       }
                   4580:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4581:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4582:         fprintf(ficresp, " Age");
                   4583:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4584:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4585:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4586:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4587:       }
1.265     brouard  4588:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4589:       fprintf(ficresphtm, "\n");
                   4590:       
                   4591:       /* Header of frequency table by age */
                   4592:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4593:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4594:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4595:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4596:          if(s2!=0 && m!=0)
                   4597:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4598:        }
1.226     brouard  4599:       }
1.251     brouard  4600:       fprintf(ficresphtmfr, "\n");
                   4601:     
                   4602:       /* For each age */
                   4603:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4604:        fprintf(ficresphtm,"<tr>");
                   4605:        if(iage==iagemax+1){
                   4606:          fprintf(ficlog,"1");
                   4607:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4608:        }else if(iage==iagemax+2){
                   4609:          fprintf(ficlog,"0");
                   4610:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4611:        }else if(iage==iagemax+3){
                   4612:          fprintf(ficlog,"Total");
                   4613:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4614:        }else{
1.240     brouard  4615:          if(first==1){
1.251     brouard  4616:            first=0;
                   4617:            printf("See log file for details...\n");
                   4618:          }
                   4619:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4620:          fprintf(ficlog,"Age %d", iage);
                   4621:        }
1.265     brouard  4622:        for(s1=1; s1 <=nlstate ; s1++){
                   4623:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4624:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4625:        }
1.265     brouard  4626:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4627:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4628:            pos += freq[s1][m][iage];
                   4629:          if(pp[s1]>=1.e-10){
1.251     brouard  4630:            if(first==1){
1.265     brouard  4631:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4632:            }
1.265     brouard  4633:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4634:          }else{
                   4635:            if(first==1)
1.265     brouard  4636:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4637:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4638:          }
                   4639:        }
                   4640:       
1.265     brouard  4641:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4642:          /* posprop[s1]=0; */
                   4643:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4644:            pp[s1] += freq[s1][m][iage];
                   4645:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4646:       
                   4647:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4648:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4649:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4650:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4651:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4652:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4653:        }
                   4654:        
                   4655:        /* Writing ficresp */
                   4656:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4657:           if( iage <= iagemax){
                   4658:            fprintf(ficresp," %d",iage);
                   4659:           }
                   4660:         }else if( nj==2){
                   4661:           if( iage <= iagemax){
                   4662:            fprintf(ficresp," %d",iage);
                   4663:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4664:           }
1.240     brouard  4665:        }
1.265     brouard  4666:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4667:          if(pos>=1.e-5){
1.251     brouard  4668:            if(first==1)
1.265     brouard  4669:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4670:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4671:          }else{
                   4672:            if(first==1)
1.265     brouard  4673:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4674:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4675:          }
                   4676:          if( iage <= iagemax){
                   4677:            if(pos>=1.e-5){
1.265     brouard  4678:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4679:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4680:               }else if( nj==2){
                   4681:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4682:               }
                   4683:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4684:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4685:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4686:            } else{
                   4687:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4688:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4689:            }
1.240     brouard  4690:          }
1.265     brouard  4691:          pospropt[s1] +=posprop[s1];
                   4692:        } /* end loop s1 */
1.251     brouard  4693:        /* pospropt=0.; */
1.265     brouard  4694:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4695:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4696:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4697:              if(first==1){
1.265     brouard  4698:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4699:              }
1.265     brouard  4700:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4701:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4702:            }
1.265     brouard  4703:            if(s1!=0 && m!=0)
                   4704:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4705:          }
1.265     brouard  4706:        } /* end loop s1 */
1.251     brouard  4707:        posproptt=0.; 
1.265     brouard  4708:        for(s1=1; s1 <=nlstate; s1++){
                   4709:          posproptt += pospropt[s1];
1.251     brouard  4710:        }
                   4711:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4712:        fprintf(ficresphtm,"</tr>\n");
                   4713:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4714:          if(iage <= iagemax)
                   4715:            fprintf(ficresp,"\n");
1.240     brouard  4716:        }
1.251     brouard  4717:        if(first==1)
                   4718:          printf("Others in log...\n");
                   4719:        fprintf(ficlog,"\n");
                   4720:       } /* end loop age iage */
1.265     brouard  4721:       
1.251     brouard  4722:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4723:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4724:        if(posproptt < 1.e-5){
1.265     brouard  4725:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4726:        }else{
1.265     brouard  4727:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4728:        }
1.226     brouard  4729:       }
1.251     brouard  4730:       fprintf(ficresphtm,"</tr>\n");
                   4731:       fprintf(ficresphtm,"</table>\n");
                   4732:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4733:       if(posproptt < 1.e-5){
1.251     brouard  4734:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4735:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4736:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4737:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4738:        invalidvarcomb[j1]=1;
1.226     brouard  4739:       }else{
1.251     brouard  4740:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4741:        invalidvarcomb[j1]=0;
1.226     brouard  4742:       }
1.251     brouard  4743:       fprintf(ficresphtmfr,"</table>\n");
                   4744:       fprintf(ficlog,"\n");
                   4745:       if(j!=0){
                   4746:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4747:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4748:          for(k=1; k <=(nlstate+ndeath); k++){
                   4749:            if (k != i) {
1.265     brouard  4750:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4751:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4752:                  if(j1==1){ /* All dummy covariates to zero */
                   4753:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4754:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4755:                    printf("%d%d ",i,k);
                   4756:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4757:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4758:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4759:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4760:                  }
1.253     brouard  4761:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4762:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4763:                    x[iage]= (double)iage;
                   4764:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4765:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4766:                  }
1.268     brouard  4767:                  /* Some are not finite, but linreg will ignore these ages */
                   4768:                  no=0;
1.253     brouard  4769:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4770:                  pstart[s1]=b;
                   4771:                  pstart[s1-1]=a;
1.252     brouard  4772:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4773:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4774:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4775:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4776:                  printf("%d%d ",i,k);
                   4777:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4778:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4779:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4780:                  ;
                   4781:                }
                   4782:                /* printf("%12.7f )", param[i][jj][k]); */
                   4783:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4784:                s1++; 
1.251     brouard  4785:              } /* end jj */
                   4786:            } /* end k!= i */
                   4787:          } /* end k */
1.265     brouard  4788:        } /* end i, s1 */
1.251     brouard  4789:       } /* end j !=0 */
                   4790:     } /* end selected combination of covariate j1 */
                   4791:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4792:       printf("#Freqsummary: Starting values for the constants:\n");
                   4793:       fprintf(ficlog,"\n");
1.265     brouard  4794:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4795:        for(k=1; k <=(nlstate+ndeath); k++){
                   4796:          if (k != i) {
                   4797:            printf("%d%d ",i,k);
                   4798:            fprintf(ficlog,"%d%d ",i,k);
                   4799:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4800:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4801:              if(jj==1){ /* Age has to be done */
1.265     brouard  4802:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4803:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4804:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4805:              }
                   4806:              /* printf("%12.7f )", param[i][jj][k]); */
                   4807:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4808:              s1++; 
1.250     brouard  4809:            }
1.251     brouard  4810:            printf("\n");
                   4811:            fprintf(ficlog,"\n");
1.250     brouard  4812:          }
                   4813:        }
                   4814:       }
1.251     brouard  4815:       printf("#Freqsummary\n");
                   4816:       fprintf(ficlog,"\n");
1.265     brouard  4817:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4818:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4819:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4820:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4821:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4822:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4823:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4824:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4825:          /* } */
                   4826:        }
1.265     brouard  4827:       } /* end loop s1 */
1.251     brouard  4828:       
                   4829:       printf("\n");
                   4830:       fprintf(ficlog,"\n");
                   4831:     } /* end j=0 */
1.249     brouard  4832:   } /* end j */
1.252     brouard  4833: 
1.253     brouard  4834:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4835:     for(i=1, jk=1; i <=nlstate; i++){
                   4836:       for(j=1; j <=nlstate+ndeath; j++){
                   4837:        if(j!=i){
                   4838:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4839:          printf("%1d%1d",i,j);
                   4840:          fprintf(ficparo,"%1d%1d",i,j);
                   4841:          for(k=1; k<=ncovmodel;k++){
                   4842:            /*    printf(" %lf",param[i][j][k]); */
                   4843:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4844:            p[jk]=pstart[jk];
                   4845:            printf(" %f ",pstart[jk]);
                   4846:            fprintf(ficparo," %f ",pstart[jk]);
                   4847:            jk++;
                   4848:          }
                   4849:          printf("\n");
                   4850:          fprintf(ficparo,"\n");
                   4851:        }
                   4852:       }
                   4853:     }
                   4854:   } /* end mle=-2 */
1.226     brouard  4855:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4856:   
1.226     brouard  4857:   fclose(ficresp);
                   4858:   fclose(ficresphtm);
                   4859:   fclose(ficresphtmfr);
                   4860:   free_vector(meanq,1,nqfveff);
                   4861:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4862:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4863:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4864:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4865:   free_vector(pospropt,1,nlstate);
                   4866:   free_vector(posprop,1,nlstate);
1.251     brouard  4867:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4868:   free_vector(pp,1,nlstate);
                   4869:   /* End of freqsummary */
                   4870: }
1.126     brouard  4871: 
1.268     brouard  4872: /* Simple linear regression */
                   4873: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4874: 
                   4875:   /* y=a+bx regression */
                   4876:   double   sumx = 0.0;                        /* sum of x                      */
                   4877:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4878:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4879:   double   sumy = 0.0;                        /* sum of y                      */
                   4880:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4881:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4882:   double yhat;
                   4883:   
                   4884:   double denom=0;
                   4885:   int i;
                   4886:   int ne=*no;
                   4887:   
                   4888:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4889:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4890:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4891:       continue;
                   4892:     }
                   4893:     ne=ne+1;
                   4894:     sumx  += x[i];       
                   4895:     sumx2 += x[i]*x[i];  
                   4896:     sumxy += x[i] * y[i];
                   4897:     sumy  += y[i];      
                   4898:     sumy2 += y[i]*y[i]; 
                   4899:     denom = (ne * sumx2 - sumx*sumx);
                   4900:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4901:   } 
                   4902:   
                   4903:   denom = (ne * sumx2 - sumx*sumx);
                   4904:   if (denom == 0) {
                   4905:     // vertical, slope m is infinity
                   4906:     *b = INFINITY;
                   4907:     *a = 0;
                   4908:     if (r) *r = 0;
                   4909:     return 1;
                   4910:   }
                   4911:   
                   4912:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4913:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4914:   if (r!=NULL) {
                   4915:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4916:       sqrt((sumx2 - sumx*sumx/ne) *
                   4917:           (sumy2 - sumy*sumy/ne));
                   4918:   }
                   4919:   *no=ne;
                   4920:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4921:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4922:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4923:       continue;
                   4924:     }
                   4925:     ne=ne+1;
                   4926:     yhat = y[i] - *a -*b* x[i];
                   4927:     sume2  += yhat * yhat ;       
                   4928:     
                   4929:     denom = (ne * sumx2 - sumx*sumx);
                   4930:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4931:   } 
                   4932:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4933:   *sa= *sb * sqrt(sumx2/ne);
                   4934:   
                   4935:   return 0; 
                   4936: }
                   4937: 
1.126     brouard  4938: /************ Prevalence ********************/
1.227     brouard  4939: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4940: {  
                   4941:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4942:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4943:      We still use firstpass and lastpass as another selection.
                   4944:   */
1.126     brouard  4945:  
1.227     brouard  4946:   int i, m, jk, j1, bool, z1,j, iv;
                   4947:   int mi; /* Effective wave */
                   4948:   int iage;
                   4949:   double agebegin, ageend;
                   4950: 
                   4951:   double **prop;
                   4952:   double posprop; 
                   4953:   double  y2; /* in fractional years */
                   4954:   int iagemin, iagemax;
                   4955:   int first; /** to stop verbosity which is redirected to log file */
                   4956: 
                   4957:   iagemin= (int) agemin;
                   4958:   iagemax= (int) agemax;
                   4959:   /*pp=vector(1,nlstate);*/
1.251     brouard  4960:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4961:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4962:   j1=0;
1.222     brouard  4963:   
1.227     brouard  4964:   /*j=cptcoveff;*/
                   4965:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4966:   
1.227     brouard  4967:   first=1;
                   4968:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4969:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4970:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4971:        prop[i][iage]=0.0;
                   4972:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4973:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4974:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4975:     
                   4976:     for (i=1; i<=imx; i++) { /* Each individual */
                   4977:       bool=1;
                   4978:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4979:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4980:        m=mw[mi][i];
                   4981:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4982:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4983:        for (z1=1; z1<=cptcoveff; z1++){
                   4984:          if( Fixed[Tmodelind[z1]]==1){
                   4985:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4986:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4987:              bool=0;
                   4988:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4989:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4990:              bool=0;
                   4991:            }
                   4992:        }
                   4993:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4994:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4995:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4996:          if(m >=firstpass && m <=lastpass){
                   4997:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4998:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4999:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5000:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5001:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5002:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5003:                exit(1);
                   5004:              }
                   5005:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5006:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5007:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5008:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5009:              } /* end valid statuses */ 
                   5010:            } /* end selection of dates */
                   5011:          } /* end selection of waves */
                   5012:        } /* end bool */
                   5013:       } /* end wave */
                   5014:     } /* end individual */
                   5015:     for(i=iagemin; i <= iagemax+3; i++){  
                   5016:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5017:        posprop += prop[jk][i]; 
                   5018:       } 
                   5019:       
                   5020:       for(jk=1; jk <=nlstate ; jk++){      
                   5021:        if( i <=  iagemax){ 
                   5022:          if(posprop>=1.e-5){ 
                   5023:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5024:          } else{
                   5025:            if(first==1){
                   5026:              first=0;
1.266     brouard  5027:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5028:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5029:            }else{
                   5030:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5031:            }
                   5032:          }
                   5033:        } 
                   5034:       }/* end jk */ 
                   5035:     }/* end i */ 
1.222     brouard  5036:      /*} *//* end i1 */
1.227     brouard  5037:   } /* end j1 */
1.222     brouard  5038:   
1.227     brouard  5039:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5040:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5041:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5042: }  /* End of prevalence */
1.126     brouard  5043: 
                   5044: /************* Waves Concatenation ***************/
                   5045: 
                   5046: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5047: {
                   5048:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5049:      Death is a valid wave (if date is known).
                   5050:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5051:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5052:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5053:   */
1.126     brouard  5054: 
1.224     brouard  5055:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5056:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5057:      double sum=0., jmean=0.;*/
1.224     brouard  5058:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5059:   int j, k=0,jk, ju, jl;
                   5060:   double sum=0.;
                   5061:   first=0;
1.214     brouard  5062:   firstwo=0;
1.217     brouard  5063:   firsthree=0;
1.218     brouard  5064:   firstfour=0;
1.164     brouard  5065:   jmin=100000;
1.126     brouard  5066:   jmax=-1;
                   5067:   jmean=0.;
1.224     brouard  5068: 
                   5069: /* Treating live states */
1.214     brouard  5070:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5071:     mi=0;  /* First valid wave */
1.227     brouard  5072:     mli=0; /* Last valid wave */
1.126     brouard  5073:     m=firstpass;
1.214     brouard  5074:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5075:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5076:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5077:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5078:        mw[++mi][i]=m;
                   5079:        mli=m;
1.224     brouard  5080:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5081:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5082:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5083:       }
1.227     brouard  5084:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5085: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5086:        break;
1.224     brouard  5087: #else
1.227     brouard  5088:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5089:          if(firsthree == 0){
1.262     brouard  5090:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5091:            firsthree=1;
                   5092:          }
1.262     brouard  5093:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5094:          mw[++mi][i]=m;
                   5095:          mli=m;
                   5096:        }
                   5097:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5098:          nbwarn++;
                   5099:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5100:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5101:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5102:          }
                   5103:          break;
                   5104:        }
                   5105:        break;
1.224     brouard  5106: #endif
1.227     brouard  5107:       }/* End m >= lastpass */
1.126     brouard  5108:     }/* end while */
1.224     brouard  5109: 
1.227     brouard  5110:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5111:     /* After last pass */
1.224     brouard  5112: /* Treating death states */
1.214     brouard  5113:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5114:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5115:       /* } */
1.126     brouard  5116:       mi++;    /* Death is another wave */
                   5117:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5118:       /* Only death is a correct wave */
1.126     brouard  5119:       mw[mi][i]=m;
1.257     brouard  5120:     } /* else not in a death state */
1.224     brouard  5121: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5122:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5123:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5124:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5125:          nbwarn++;
                   5126:          if(firstfiv==0){
                   5127:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5128:            firstfiv=1;
                   5129:          }else{
                   5130:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5131:          }
                   5132:        }else{ /* Death occured afer last wave potential bias */
                   5133:          nberr++;
                   5134:          if(firstwo==0){
1.257     brouard  5135:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5136:            firstwo=1;
                   5137:          }
1.257     brouard  5138:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5139:        }
1.257     brouard  5140:       }else{ /* if date of interview is unknown */
1.227     brouard  5141:        /* death is known but not confirmed by death status at any wave */
                   5142:        if(firstfour==0){
                   5143:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5144:          firstfour=1;
                   5145:        }
                   5146:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5147:       }
1.224     brouard  5148:     } /* end if date of death is known */
                   5149: #endif
                   5150:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5151:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5152:     if(mi==0){
                   5153:       nbwarn++;
                   5154:       if(first==0){
1.227     brouard  5155:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5156:        first=1;
1.126     brouard  5157:       }
                   5158:       if(first==1){
1.227     brouard  5159:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5160:       }
                   5161:     } /* end mi==0 */
                   5162:   } /* End individuals */
1.214     brouard  5163:   /* wav and mw are no more changed */
1.223     brouard  5164:        
1.214     brouard  5165:   
1.126     brouard  5166:   for(i=1; i<=imx; i++){
                   5167:     for(mi=1; mi<wav[i];mi++){
                   5168:       if (stepm <=0)
1.227     brouard  5169:        dh[mi][i]=1;
1.126     brouard  5170:       else{
1.260     brouard  5171:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5172:          if (agedc[i] < 2*AGESUP) {
                   5173:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5174:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5175:            else if(j<0){
                   5176:              nberr++;
                   5177:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5178:              j=1; /* Temporary Dangerous patch */
                   5179:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5180:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5181:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5182:            }
                   5183:            k=k+1;
                   5184:            if (j >= jmax){
                   5185:              jmax=j;
                   5186:              ijmax=i;
                   5187:            }
                   5188:            if (j <= jmin){
                   5189:              jmin=j;
                   5190:              ijmin=i;
                   5191:            }
                   5192:            sum=sum+j;
                   5193:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5194:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5195:          }
                   5196:        }
                   5197:        else{
                   5198:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5199: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5200:                                        
1.227     brouard  5201:          k=k+1;
                   5202:          if (j >= jmax) {
                   5203:            jmax=j;
                   5204:            ijmax=i;
                   5205:          }
                   5206:          else if (j <= jmin){
                   5207:            jmin=j;
                   5208:            ijmin=i;
                   5209:          }
                   5210:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5211:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5212:          if(j<0){
                   5213:            nberr++;
                   5214:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5215:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5216:          }
                   5217:          sum=sum+j;
                   5218:        }
                   5219:        jk= j/stepm;
                   5220:        jl= j -jk*stepm;
                   5221:        ju= j -(jk+1)*stepm;
                   5222:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5223:          if(jl==0){
                   5224:            dh[mi][i]=jk;
                   5225:            bh[mi][i]=0;
                   5226:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5227:                  * to avoid the price of an extra matrix product in likelihood */
                   5228:            dh[mi][i]=jk+1;
                   5229:            bh[mi][i]=ju;
                   5230:          }
                   5231:        }else{
                   5232:          if(jl <= -ju){
                   5233:            dh[mi][i]=jk;
                   5234:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5235:                                 * is higher than the multiple of stepm and negative otherwise.
                   5236:                                 */
                   5237:          }
                   5238:          else{
                   5239:            dh[mi][i]=jk+1;
                   5240:            bh[mi][i]=ju;
                   5241:          }
                   5242:          if(dh[mi][i]==0){
                   5243:            dh[mi][i]=1; /* At least one step */
                   5244:            bh[mi][i]=ju; /* At least one step */
                   5245:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5246:          }
                   5247:        } /* end if mle */
1.126     brouard  5248:       }
                   5249:     } /* end wave */
                   5250:   }
                   5251:   jmean=sum/k;
                   5252:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5253:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5254: }
1.126     brouard  5255: 
                   5256: /*********** Tricode ****************************/
1.220     brouard  5257:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5258:  {
                   5259:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5260:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5261:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5262:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5263:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5264:     */
1.130     brouard  5265: 
1.242     brouard  5266:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5267:    int modmaxcovj=0; /* Modality max of covariates j */
                   5268:    int cptcode=0; /* Modality max of covariates j */
                   5269:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5270: 
                   5271: 
1.242     brouard  5272:    /* cptcoveff=0;  */
                   5273:    /* *cptcov=0; */
1.126     brouard  5274:  
1.242     brouard  5275:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5276: 
1.242     brouard  5277:    /* Loop on covariates without age and products and no quantitative variable */
                   5278:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5279:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5280:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5281:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5282:        switch(Fixed[k]) {
                   5283:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5284:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5285:           ij=(int)(covar[Tvar[k]][i]);
                   5286:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5287:            * If product of Vn*Vm, still boolean *:
                   5288:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5289:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5290:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5291:              modality of the nth covariate of individual i. */
                   5292:           if (ij > modmaxcovj)
                   5293:             modmaxcovj=ij; 
                   5294:           else if (ij < modmincovj) 
                   5295:             modmincovj=ij; 
                   5296:           if ((ij < -1) && (ij > NCOVMAX)){
                   5297:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5298:             exit(1);
                   5299:           }else
                   5300:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5301:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5302:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5303:           /* getting the maximum value of the modality of the covariate
                   5304:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5305:              female ies 1, then modmaxcovj=1.
                   5306:           */
                   5307:         } /* end for loop on individuals i */
                   5308:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5309:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5310:         cptcode=modmaxcovj;
                   5311:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5312:         /*for (i=0; i<=cptcode; i++) {*/
                   5313:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5314:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5315:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5316:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5317:             if( j != -1){
                   5318:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5319:                                  covariate for which somebody answered excluding 
                   5320:                                  undefined. Usually 2: 0 and 1. */
                   5321:             }
                   5322:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5323:                                     covariate for which somebody answered including 
                   5324:                                     undefined. Usually 3: -1, 0 and 1. */
                   5325:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5326:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5327:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5328:                        
1.242     brouard  5329:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5330:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5331:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5332:         /* modmincovj=3; modmaxcovj = 7; */
                   5333:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5334:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5335:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5336:         /* nbcode[Tvar[j]][ij]=k; */
                   5337:         /* nbcode[Tvar[j]][1]=0; */
                   5338:         /* nbcode[Tvar[j]][2]=1; */
                   5339:         /* nbcode[Tvar[j]][3]=2; */
                   5340:         /* To be continued (not working yet). */
                   5341:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5342:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5343:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5344:             break;
                   5345:           }
                   5346:           ij++;
                   5347:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5348:           cptcode = ij; /* New max modality for covar j */
                   5349:         } /* end of loop on modality i=-1 to 1 or more */
                   5350:         break;
                   5351:        case 1: /* Testing on varying covariate, could be simple and
                   5352:                * should look at waves or product of fixed *
                   5353:                * varying. No time to test -1, assuming 0 and 1 only */
                   5354:         ij=0;
                   5355:         for(i=0; i<=1;i++){
                   5356:           nbcode[Tvar[k]][++ij]=i;
                   5357:         }
                   5358:         break;
                   5359:        default:
                   5360:         break;
                   5361:        } /* end switch */
                   5362:      } /* end dummy test */
                   5363:     
                   5364:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5365:      /*        /\*recode from 0 *\/ */
                   5366:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5367:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5368:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5369:      /*        } */
                   5370:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5371:      /*        if (ij > ncodemax[j]) { */
                   5372:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5373:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5374:      /*          break; */
                   5375:      /*        } */
                   5376:      /*   }  /\* end of loop on modality k *\/ */
                   5377:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5378:   
                   5379:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5380:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5381:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5382:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5383:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5384:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5385:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5386:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5387:   
                   5388:    ij=0;
                   5389:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5390:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5391:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5392:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5393:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5394:        /* If product not in single variable we don't print results */
                   5395:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5396:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5397:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5398:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5399:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5400:        if(Fixed[k]!=0)
                   5401:         anyvaryingduminmodel=1;
                   5402:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5403:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5404:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5405:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5406:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5407:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5408:      } 
                   5409:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5410:    /* ij--; */
                   5411:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5412:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5413:                * because they can be excluded from the model and real
                   5414:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5415:    for(j=ij+1; j<= cptcovt; j++){
                   5416:      Tvaraff[j]=0;
                   5417:      Tmodelind[j]=0;
                   5418:    }
                   5419:    for(j=ntveff+1; j<= cptcovt; j++){
                   5420:      TmodelInvind[j]=0;
                   5421:    }
                   5422:    /* To be sorted */
                   5423:    ;
                   5424:  }
1.126     brouard  5425: 
1.145     brouard  5426: 
1.126     brouard  5427: /*********** Health Expectancies ****************/
                   5428: 
1.235     brouard  5429:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5430: 
                   5431: {
                   5432:   /* Health expectancies, no variances */
1.164     brouard  5433:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5434:   int nhstepma, nstepma; /* Decreasing with age */
                   5435:   double age, agelim, hf;
                   5436:   double ***p3mat;
                   5437:   double eip;
                   5438: 
1.238     brouard  5439:   /* pstamp(ficreseij); */
1.126     brouard  5440:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5441:   fprintf(ficreseij,"# Age");
                   5442:   for(i=1; i<=nlstate;i++){
                   5443:     for(j=1; j<=nlstate;j++){
                   5444:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5445:     }
                   5446:     fprintf(ficreseij," e%1d. ",i);
                   5447:   }
                   5448:   fprintf(ficreseij,"\n");
                   5449: 
                   5450:   
                   5451:   if(estepm < stepm){
                   5452:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5453:   }
                   5454:   else  hstepm=estepm;   
                   5455:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5456:    * This is mainly to measure the difference between two models: for example
                   5457:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5458:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5459:    * progression in between and thus overestimating or underestimating according
                   5460:    * to the curvature of the survival function. If, for the same date, we 
                   5461:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5462:    * to compare the new estimate of Life expectancy with the same linear 
                   5463:    * hypothesis. A more precise result, taking into account a more precise
                   5464:    * curvature will be obtained if estepm is as small as stepm. */
                   5465: 
                   5466:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5467:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5468:      nhstepm is the number of hstepm from age to agelim 
                   5469:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5470:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5471:      and note for a fixed period like estepm months */
                   5472:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5473:      survival function given by stepm (the optimization length). Unfortunately it
                   5474:      means that if the survival funtion is printed only each two years of age and if
                   5475:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5476:      results. So we changed our mind and took the option of the best precision.
                   5477:   */
                   5478:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5479: 
                   5480:   agelim=AGESUP;
                   5481:   /* If stepm=6 months */
                   5482:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5483:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5484:     
                   5485: /* nhstepm age range expressed in number of stepm */
                   5486:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5487:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5488:   /* if (stepm >= YEARM) hstepm=1;*/
                   5489:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5490:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5491: 
                   5492:   for (age=bage; age<=fage; age ++){ 
                   5493:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5494:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5495:     /* if (stepm >= YEARM) hstepm=1;*/
                   5496:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5497: 
                   5498:     /* If stepm=6 months */
                   5499:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5500:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5501:     
1.235     brouard  5502:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5503:     
                   5504:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5505:     
                   5506:     printf("%d|",(int)age);fflush(stdout);
                   5507:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5508:     
                   5509:     /* Computing expectancies */
                   5510:     for(i=1; i<=nlstate;i++)
                   5511:       for(j=1; j<=nlstate;j++)
                   5512:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5513:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5514:          
                   5515:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5516: 
                   5517:        }
                   5518: 
                   5519:     fprintf(ficreseij,"%3.0f",age );
                   5520:     for(i=1; i<=nlstate;i++){
                   5521:       eip=0;
                   5522:       for(j=1; j<=nlstate;j++){
                   5523:        eip +=eij[i][j][(int)age];
                   5524:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5525:       }
                   5526:       fprintf(ficreseij,"%9.4f", eip );
                   5527:     }
                   5528:     fprintf(ficreseij,"\n");
                   5529:     
                   5530:   }
                   5531:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5532:   printf("\n");
                   5533:   fprintf(ficlog,"\n");
                   5534:   
                   5535: }
                   5536: 
1.235     brouard  5537:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5538: 
                   5539: {
                   5540:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5541:      to initial status i, ei. .
1.126     brouard  5542:   */
                   5543:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5544:   int nhstepma, nstepma; /* Decreasing with age */
                   5545:   double age, agelim, hf;
                   5546:   double ***p3matp, ***p3matm, ***varhe;
                   5547:   double **dnewm,**doldm;
                   5548:   double *xp, *xm;
                   5549:   double **gp, **gm;
                   5550:   double ***gradg, ***trgradg;
                   5551:   int theta;
                   5552: 
                   5553:   double eip, vip;
                   5554: 
                   5555:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5556:   xp=vector(1,npar);
                   5557:   xm=vector(1,npar);
                   5558:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5559:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5560:   
                   5561:   pstamp(ficresstdeij);
                   5562:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5563:   fprintf(ficresstdeij,"# Age");
                   5564:   for(i=1; i<=nlstate;i++){
                   5565:     for(j=1; j<=nlstate;j++)
                   5566:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5567:     fprintf(ficresstdeij," e%1d. ",i);
                   5568:   }
                   5569:   fprintf(ficresstdeij,"\n");
                   5570: 
                   5571:   pstamp(ficrescveij);
                   5572:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5573:   fprintf(ficrescveij,"# Age");
                   5574:   for(i=1; i<=nlstate;i++)
                   5575:     for(j=1; j<=nlstate;j++){
                   5576:       cptj= (j-1)*nlstate+i;
                   5577:       for(i2=1; i2<=nlstate;i2++)
                   5578:        for(j2=1; j2<=nlstate;j2++){
                   5579:          cptj2= (j2-1)*nlstate+i2;
                   5580:          if(cptj2 <= cptj)
                   5581:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5582:        }
                   5583:     }
                   5584:   fprintf(ficrescveij,"\n");
                   5585:   
                   5586:   if(estepm < stepm){
                   5587:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5588:   }
                   5589:   else  hstepm=estepm;   
                   5590:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5591:    * This is mainly to measure the difference between two models: for example
                   5592:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5593:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5594:    * progression in between and thus overestimating or underestimating according
                   5595:    * to the curvature of the survival function. If, for the same date, we 
                   5596:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5597:    * to compare the new estimate of Life expectancy with the same linear 
                   5598:    * hypothesis. A more precise result, taking into account a more precise
                   5599:    * curvature will be obtained if estepm is as small as stepm. */
                   5600: 
                   5601:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5602:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5603:      nhstepm is the number of hstepm from age to agelim 
                   5604:      nstepm is the number of stepm from age to agelin. 
                   5605:      Look at hpijx to understand the reason of that which relies in memory size
                   5606:      and note for a fixed period like estepm months */
                   5607:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5608:      survival function given by stepm (the optimization length). Unfortunately it
                   5609:      means that if the survival funtion is printed only each two years of age and if
                   5610:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5611:      results. So we changed our mind and took the option of the best precision.
                   5612:   */
                   5613:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5614: 
                   5615:   /* If stepm=6 months */
                   5616:   /* nhstepm age range expressed in number of stepm */
                   5617:   agelim=AGESUP;
                   5618:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5619:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5620:   /* if (stepm >= YEARM) hstepm=1;*/
                   5621:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5622:   
                   5623:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5624:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5625:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5626:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5627:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5628:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5629: 
                   5630:   for (age=bage; age<=fage; age ++){ 
                   5631:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5632:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5633:     /* if (stepm >= YEARM) hstepm=1;*/
                   5634:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5635:                
1.126     brouard  5636:     /* If stepm=6 months */
                   5637:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5638:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5639:     
                   5640:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5641:                
1.126     brouard  5642:     /* Computing  Variances of health expectancies */
                   5643:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5644:        decrease memory allocation */
                   5645:     for(theta=1; theta <=npar; theta++){
                   5646:       for(i=1; i<=npar; i++){ 
1.222     brouard  5647:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5648:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5649:       }
1.235     brouard  5650:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5651:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5652:                        
1.126     brouard  5653:       for(j=1; j<= nlstate; j++){
1.222     brouard  5654:        for(i=1; i<=nlstate; i++){
                   5655:          for(h=0; h<=nhstepm-1; h++){
                   5656:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5657:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5658:          }
                   5659:        }
1.126     brouard  5660:       }
1.218     brouard  5661:                        
1.126     brouard  5662:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5663:        for(h=0; h<=nhstepm-1; h++){
                   5664:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5665:        }
1.126     brouard  5666:     }/* End theta */
                   5667:     
                   5668:     
                   5669:     for(h=0; h<=nhstepm-1; h++)
                   5670:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5671:        for(theta=1; theta <=npar; theta++)
                   5672:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5673:     
1.218     brouard  5674:                
1.222     brouard  5675:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5676:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5677:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5678:                
1.222     brouard  5679:     printf("%d|",(int)age);fflush(stdout);
                   5680:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5681:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5682:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5683:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5684:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5685:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5686:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5687:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5688:       }
                   5689:     }
1.218     brouard  5690:                
1.126     brouard  5691:     /* Computing expectancies */
1.235     brouard  5692:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5693:     for(i=1; i<=nlstate;i++)
                   5694:       for(j=1; j<=nlstate;j++)
1.222     brouard  5695:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5696:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5697:                                        
1.222     brouard  5698:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5699:                                        
1.222     brouard  5700:        }
1.269     brouard  5701: 
                   5702:     /* Standard deviation of expectancies ij */                
1.126     brouard  5703:     fprintf(ficresstdeij,"%3.0f",age );
                   5704:     for(i=1; i<=nlstate;i++){
                   5705:       eip=0.;
                   5706:       vip=0.;
                   5707:       for(j=1; j<=nlstate;j++){
1.222     brouard  5708:        eip += eij[i][j][(int)age];
                   5709:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5710:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5711:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5712:       }
                   5713:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5714:     }
                   5715:     fprintf(ficresstdeij,"\n");
1.218     brouard  5716:                
1.269     brouard  5717:     /* Variance of expectancies ij */          
1.126     brouard  5718:     fprintf(ficrescveij,"%3.0f",age );
                   5719:     for(i=1; i<=nlstate;i++)
                   5720:       for(j=1; j<=nlstate;j++){
1.222     brouard  5721:        cptj= (j-1)*nlstate+i;
                   5722:        for(i2=1; i2<=nlstate;i2++)
                   5723:          for(j2=1; j2<=nlstate;j2++){
                   5724:            cptj2= (j2-1)*nlstate+i2;
                   5725:            if(cptj2 <= cptj)
                   5726:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5727:          }
1.126     brouard  5728:       }
                   5729:     fprintf(ficrescveij,"\n");
1.218     brouard  5730:                
1.126     brouard  5731:   }
                   5732:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5733:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5734:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5735:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5736:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5737:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5738:   printf("\n");
                   5739:   fprintf(ficlog,"\n");
1.218     brouard  5740:        
1.126     brouard  5741:   free_vector(xm,1,npar);
                   5742:   free_vector(xp,1,npar);
                   5743:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5744:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5745:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5746: }
1.218     brouard  5747:  
1.126     brouard  5748: /************ Variance ******************/
1.235     brouard  5749:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5750:  {
                   5751:    /* Variance of health expectancies */
                   5752:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5753:    /* double **newm;*/
                   5754:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5755:   
                   5756:    /* int movingaverage(); */
                   5757:    double **dnewm,**doldm;
                   5758:    double **dnewmp,**doldmp;
                   5759:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5760:    int k;
                   5761:    double *xp;
                   5762:    double **gp, **gm;  /* for var eij */
                   5763:    double ***gradg, ***trgradg; /*for var eij */
                   5764:    double **gradgp, **trgradgp; /* for var p point j */
                   5765:    double *gpp, *gmp; /* for var p point j */
                   5766:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5767:    double ***p3mat;
                   5768:    double age,agelim, hf;
                   5769:    /* double ***mobaverage; */
                   5770:    int theta;
                   5771:    char digit[4];
                   5772:    char digitp[25];
                   5773: 
                   5774:    char fileresprobmorprev[FILENAMELENGTH];
                   5775: 
                   5776:    if(popbased==1){
                   5777:      if(mobilav!=0)
                   5778:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5779:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5780:    }
                   5781:    else 
                   5782:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5783: 
1.218     brouard  5784:    /* if (mobilav!=0) { */
                   5785:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5786:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5787:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5788:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5789:    /*   } */
                   5790:    /* } */
                   5791: 
                   5792:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5793:    sprintf(digit,"%-d",ij);
                   5794:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5795:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5796:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5797:    strcat(fileresprobmorprev,fileresu);
                   5798:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5799:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5800:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5801:    }
                   5802:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5803:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5804:    pstamp(ficresprobmorprev);
                   5805:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5806:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5807:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5808:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5809:    }
                   5810:    for(j=1;j<=cptcoveff;j++) 
                   5811:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5812:    fprintf(ficresprobmorprev,"\n");
                   5813: 
1.218     brouard  5814:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5815:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5816:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5817:      for(i=1; i<=nlstate;i++)
                   5818:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5819:    }  
                   5820:    fprintf(ficresprobmorprev,"\n");
                   5821:   
                   5822:    fprintf(ficgp,"\n# Routine varevsij");
                   5823:    fprintf(ficgp,"\nunset title \n");
                   5824:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5825:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5826:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5827:    /*   } */
                   5828:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5829:    pstamp(ficresvij);
                   5830:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5831:    if(popbased==1)
                   5832:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5833:    else
                   5834:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5835:    fprintf(ficresvij,"# Age");
                   5836:    for(i=1; i<=nlstate;i++)
                   5837:      for(j=1; j<=nlstate;j++)
                   5838:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5839:    fprintf(ficresvij,"\n");
                   5840: 
                   5841:    xp=vector(1,npar);
                   5842:    dnewm=matrix(1,nlstate,1,npar);
                   5843:    doldm=matrix(1,nlstate,1,nlstate);
                   5844:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5845:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5846: 
                   5847:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5848:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5849:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5850:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5851:   
1.218     brouard  5852:    if(estepm < stepm){
                   5853:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5854:    }
                   5855:    else  hstepm=estepm;   
                   5856:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5857:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5858:       nhstepm is the number of hstepm from age to agelim 
                   5859:       nstepm is the number of stepm from age to agelim. 
                   5860:       Look at function hpijx to understand why because of memory size limitations, 
                   5861:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5862:       survival function given by stepm (the optimization length). Unfortunately it
                   5863:       means that if the survival funtion is printed every two years of age and if
                   5864:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5865:       results. So we changed our mind and took the option of the best precision.
                   5866:    */
                   5867:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5868:    agelim = AGESUP;
                   5869:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5870:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5871:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5872:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5873:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5874:      gp=matrix(0,nhstepm,1,nlstate);
                   5875:      gm=matrix(0,nhstepm,1,nlstate);
                   5876:                
                   5877:                
                   5878:      for(theta=1; theta <=npar; theta++){
                   5879:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5880:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5881:        }
                   5882:                        
1.242     brouard  5883:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5884:                        
                   5885:        if (popbased==1) {
                   5886:         if(mobilav ==0){
                   5887:           for(i=1; i<=nlstate;i++)
                   5888:             prlim[i][i]=probs[(int)age][i][ij];
                   5889:         }else{ /* mobilav */ 
                   5890:           for(i=1; i<=nlstate;i++)
                   5891:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5892:         }
                   5893:        }
                   5894:                        
1.235     brouard  5895:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5896:        for(j=1; j<= nlstate; j++){
                   5897:         for(h=0; h<=nhstepm; h++){
                   5898:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5899:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5900:         }
                   5901:        }
                   5902:        /* Next for computing probability of death (h=1 means
                   5903:          computed over hstepm matrices product = hstepm*stepm months) 
                   5904:          as a weighted average of prlim.
                   5905:        */
                   5906:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5907:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5908:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5909:        }    
                   5910:        /* end probability of death */
                   5911:                        
                   5912:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5913:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5914:                        
1.242     brouard  5915:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5916:                        
                   5917:        if (popbased==1) {
                   5918:         if(mobilav ==0){
                   5919:           for(i=1; i<=nlstate;i++)
                   5920:             prlim[i][i]=probs[(int)age][i][ij];
                   5921:         }else{ /* mobilav */ 
                   5922:           for(i=1; i<=nlstate;i++)
                   5923:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5924:         }
                   5925:        }
                   5926:                        
1.235     brouard  5927:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5928:                        
                   5929:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5930:         for(h=0; h<=nhstepm; h++){
                   5931:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5932:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5933:         }
                   5934:        }
                   5935:        /* This for computing probability of death (h=1 means
                   5936:          computed over hstepm matrices product = hstepm*stepm months) 
                   5937:          as a weighted average of prlim.
                   5938:        */
                   5939:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5940:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5941:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5942:        }    
                   5943:        /* end probability of death */
                   5944:                        
                   5945:        for(j=1; j<= nlstate; j++) /* vareij */
                   5946:         for(h=0; h<=nhstepm; h++){
                   5947:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5948:         }
                   5949:                        
                   5950:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5951:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5952:        }
                   5953:                        
                   5954:      } /* End theta */
                   5955:                
                   5956:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5957:                
                   5958:      for(h=0; h<=nhstepm; h++) /* veij */
                   5959:        for(j=1; j<=nlstate;j++)
                   5960:         for(theta=1; theta <=npar; theta++)
                   5961:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5962:                
                   5963:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5964:        for(theta=1; theta <=npar; theta++)
                   5965:         trgradgp[j][theta]=gradgp[theta][j];
                   5966:                
                   5967:                
                   5968:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5969:      for(i=1;i<=nlstate;i++)
                   5970:        for(j=1;j<=nlstate;j++)
                   5971:         vareij[i][j][(int)age] =0.;
                   5972:                
                   5973:      for(h=0;h<=nhstepm;h++){
                   5974:        for(k=0;k<=nhstepm;k++){
                   5975:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5976:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5977:         for(i=1;i<=nlstate;i++)
                   5978:           for(j=1;j<=nlstate;j++)
                   5979:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5980:        }
                   5981:      }
                   5982:                
                   5983:      /* pptj */
                   5984:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5985:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5986:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5987:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5988:         varppt[j][i]=doldmp[j][i];
                   5989:      /* end ppptj */
                   5990:      /*  x centered again */
                   5991:                
1.242     brouard  5992:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5993:                
                   5994:      if (popbased==1) {
                   5995:        if(mobilav ==0){
                   5996:         for(i=1; i<=nlstate;i++)
                   5997:           prlim[i][i]=probs[(int)age][i][ij];
                   5998:        }else{ /* mobilav */ 
                   5999:         for(i=1; i<=nlstate;i++)
                   6000:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6001:        }
                   6002:      }
                   6003:                
                   6004:      /* This for computing probability of death (h=1 means
                   6005:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6006:        as a weighted average of prlim.
                   6007:      */
1.235     brouard  6008:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6009:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6010:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6011:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6012:      }    
                   6013:      /* end probability of death */
                   6014:                
                   6015:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6016:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6017:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6018:        for(i=1; i<=nlstate;i++){
                   6019:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6020:        }
                   6021:      } 
                   6022:      fprintf(ficresprobmorprev,"\n");
                   6023:                
                   6024:      fprintf(ficresvij,"%.0f ",age );
                   6025:      for(i=1; i<=nlstate;i++)
                   6026:        for(j=1; j<=nlstate;j++){
                   6027:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6028:        }
                   6029:      fprintf(ficresvij,"\n");
                   6030:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6031:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6032:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6033:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6034:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6035:    } /* End age */
                   6036:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6037:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6038:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6039:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6040:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6041:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6042:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6043:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6044:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6045:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6046:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6047:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6048:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6049:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6050:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6051:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6052:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6053:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6054:     */
1.218     brouard  6055:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6056:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6057: 
1.218     brouard  6058:    free_vector(xp,1,npar);
                   6059:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6060:    free_matrix(dnewm,1,nlstate,1,npar);
                   6061:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6062:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6063:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6064:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6065:    fclose(ficresprobmorprev);
                   6066:    fflush(ficgp);
                   6067:    fflush(fichtm); 
                   6068:  }  /* end varevsij */
1.126     brouard  6069: 
                   6070: /************ Variance of prevlim ******************/
1.269     brouard  6071:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6072: {
1.205     brouard  6073:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6074:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6075: 
1.268     brouard  6076:   double **dnewmpar,**doldm;
1.126     brouard  6077:   int i, j, nhstepm, hstepm;
                   6078:   double *xp;
                   6079:   double *gp, *gm;
                   6080:   double **gradg, **trgradg;
1.208     brouard  6081:   double **mgm, **mgp;
1.126     brouard  6082:   double age,agelim;
                   6083:   int theta;
                   6084:   
                   6085:   pstamp(ficresvpl);
                   6086:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6087:   fprintf(ficresvpl,"# Age ");
                   6088:   if(nresult >=1)
                   6089:     fprintf(ficresvpl," Result# ");
1.126     brouard  6090:   for(i=1; i<=nlstate;i++)
                   6091:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6092:   fprintf(ficresvpl,"\n");
                   6093: 
                   6094:   xp=vector(1,npar);
1.268     brouard  6095:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6096:   doldm=matrix(1,nlstate,1,nlstate);
                   6097:   
                   6098:   hstepm=1*YEARM; /* Every year of age */
                   6099:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6100:   agelim = AGESUP;
                   6101:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6102:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6103:     if (stepm >= YEARM) hstepm=1;
                   6104:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6105:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6106:     mgp=matrix(1,npar,1,nlstate);
                   6107:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6108:     gp=vector(1,nlstate);
                   6109:     gm=vector(1,nlstate);
                   6110: 
                   6111:     for(theta=1; theta <=npar; theta++){
                   6112:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6113:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6114:       }
1.209     brouard  6115:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6116:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6117:       else
1.235     brouard  6118:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6119:       for(i=1;i<=nlstate;i++){
1.126     brouard  6120:        gp[i] = prlim[i][i];
1.208     brouard  6121:        mgp[theta][i] = prlim[i][i];
                   6122:       }
1.126     brouard  6123:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6124:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6125:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6126:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6127:       else
1.235     brouard  6128:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6129:       for(i=1;i<=nlstate;i++){
1.126     brouard  6130:        gm[i] = prlim[i][i];
1.208     brouard  6131:        mgm[theta][i] = prlim[i][i];
                   6132:       }
1.126     brouard  6133:       for(i=1;i<=nlstate;i++)
                   6134:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6135:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6136:     } /* End theta */
                   6137: 
                   6138:     trgradg =matrix(1,nlstate,1,npar);
                   6139: 
                   6140:     for(j=1; j<=nlstate;j++)
                   6141:       for(theta=1; theta <=npar; theta++)
                   6142:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6143:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6144:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6145:     /*   for(j=1; j<=nlstate;j++){ */
                   6146:     /*         printf(" %d ",j); */
                   6147:     /*         for(theta=1; theta <=npar; theta++) */
                   6148:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6149:     /*         printf("\n "); */
                   6150:     /*   } */
                   6151:     /* } */
                   6152:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6153:     /*   printf("\n gradg %d ",(int)age); */
                   6154:     /*   for(j=1; j<=nlstate;j++){ */
                   6155:     /*         printf("%d ",j); */
                   6156:     /*         for(theta=1; theta <=npar; theta++) */
                   6157:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6158:     /*         printf("\n "); */
                   6159:     /*   } */
                   6160:     /* } */
1.126     brouard  6161: 
                   6162:     for(i=1;i<=nlstate;i++)
                   6163:       varpl[i][(int)age] =0.;
1.209     brouard  6164:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6165:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6166:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6167:     }else{
1.268     brouard  6168:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6169:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6170:     }
1.126     brouard  6171:     for(i=1;i<=nlstate;i++)
                   6172:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6173: 
                   6174:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6175:     if(nresult >=1)
                   6176:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6177:     for(i=1; i<=nlstate;i++)
                   6178:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6179:     fprintf(ficresvpl,"\n");
                   6180:     free_vector(gp,1,nlstate);
                   6181:     free_vector(gm,1,nlstate);
1.208     brouard  6182:     free_matrix(mgm,1,npar,1,nlstate);
                   6183:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6184:     free_matrix(gradg,1,npar,1,nlstate);
                   6185:     free_matrix(trgradg,1,nlstate,1,npar);
                   6186:   } /* End age */
                   6187: 
                   6188:   free_vector(xp,1,npar);
                   6189:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6190:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6191: 
                   6192: }
                   6193: 
                   6194: 
                   6195: /************ Variance of backprevalence limit ******************/
1.269     brouard  6196:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6197: {
                   6198:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6199:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6200: 
                   6201:   double **dnewmpar,**doldm;
                   6202:   int i, j, nhstepm, hstepm;
                   6203:   double *xp;
                   6204:   double *gp, *gm;
                   6205:   double **gradg, **trgradg;
                   6206:   double **mgm, **mgp;
                   6207:   double age,agelim;
                   6208:   int theta;
                   6209:   
                   6210:   pstamp(ficresvbl);
                   6211:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6212:   fprintf(ficresvbl,"# Age ");
                   6213:   if(nresult >=1)
                   6214:     fprintf(ficresvbl," Result# ");
                   6215:   for(i=1; i<=nlstate;i++)
                   6216:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6217:   fprintf(ficresvbl,"\n");
                   6218: 
                   6219:   xp=vector(1,npar);
                   6220:   dnewmpar=matrix(1,nlstate,1,npar);
                   6221:   doldm=matrix(1,nlstate,1,nlstate);
                   6222:   
                   6223:   hstepm=1*YEARM; /* Every year of age */
                   6224:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6225:   agelim = AGEINF;
                   6226:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6227:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6228:     if (stepm >= YEARM) hstepm=1;
                   6229:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6230:     gradg=matrix(1,npar,1,nlstate);
                   6231:     mgp=matrix(1,npar,1,nlstate);
                   6232:     mgm=matrix(1,npar,1,nlstate);
                   6233:     gp=vector(1,nlstate);
                   6234:     gm=vector(1,nlstate);
                   6235: 
                   6236:     for(theta=1; theta <=npar; theta++){
                   6237:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6238:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6239:       }
                   6240:       if(mobilavproj > 0 )
                   6241:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6242:       else
                   6243:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6244:       for(i=1;i<=nlstate;i++){
                   6245:        gp[i] = bprlim[i][i];
                   6246:        mgp[theta][i] = bprlim[i][i];
                   6247:       }
                   6248:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6249:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6250:        if(mobilavproj > 0 )
                   6251:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6252:        else
                   6253:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6254:       for(i=1;i<=nlstate;i++){
                   6255:        gm[i] = bprlim[i][i];
                   6256:        mgm[theta][i] = bprlim[i][i];
                   6257:       }
                   6258:       for(i=1;i<=nlstate;i++)
                   6259:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6260:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6261:     } /* End theta */
                   6262: 
                   6263:     trgradg =matrix(1,nlstate,1,npar);
                   6264: 
                   6265:     for(j=1; j<=nlstate;j++)
                   6266:       for(theta=1; theta <=npar; theta++)
                   6267:        trgradg[j][theta]=gradg[theta][j];
                   6268:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6269:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6270:     /*   for(j=1; j<=nlstate;j++){ */
                   6271:     /*         printf(" %d ",j); */
                   6272:     /*         for(theta=1; theta <=npar; theta++) */
                   6273:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6274:     /*         printf("\n "); */
                   6275:     /*   } */
                   6276:     /* } */
                   6277:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6278:     /*   printf("\n gradg %d ",(int)age); */
                   6279:     /*   for(j=1; j<=nlstate;j++){ */
                   6280:     /*         printf("%d ",j); */
                   6281:     /*         for(theta=1; theta <=npar; theta++) */
                   6282:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6283:     /*         printf("\n "); */
                   6284:     /*   } */
                   6285:     /* } */
                   6286: 
                   6287:     for(i=1;i<=nlstate;i++)
                   6288:       varbpl[i][(int)age] =0.;
                   6289:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6290:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6291:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6292:     }else{
                   6293:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6294:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6295:     }
                   6296:     for(i=1;i<=nlstate;i++)
                   6297:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6298: 
                   6299:     fprintf(ficresvbl,"%.0f ",age );
                   6300:     if(nresult >=1)
                   6301:       fprintf(ficresvbl,"%d ",nres );
                   6302:     for(i=1; i<=nlstate;i++)
                   6303:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6304:     fprintf(ficresvbl,"\n");
                   6305:     free_vector(gp,1,nlstate);
                   6306:     free_vector(gm,1,nlstate);
                   6307:     free_matrix(mgm,1,npar,1,nlstate);
                   6308:     free_matrix(mgp,1,npar,1,nlstate);
                   6309:     free_matrix(gradg,1,npar,1,nlstate);
                   6310:     free_matrix(trgradg,1,nlstate,1,npar);
                   6311:   } /* End age */
                   6312: 
                   6313:   free_vector(xp,1,npar);
                   6314:   free_matrix(doldm,1,nlstate,1,npar);
                   6315:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6316: 
                   6317: }
                   6318: 
                   6319: /************ Variance of one-step probabilities  ******************/
                   6320: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6321:  {
                   6322:    int i, j=0,  k1, l1, tj;
                   6323:    int k2, l2, j1,  z1;
                   6324:    int k=0, l;
                   6325:    int first=1, first1, first2;
                   6326:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6327:    double **dnewm,**doldm;
                   6328:    double *xp;
                   6329:    double *gp, *gm;
                   6330:    double **gradg, **trgradg;
                   6331:    double **mu;
                   6332:    double age, cov[NCOVMAX+1];
                   6333:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6334:    int theta;
                   6335:    char fileresprob[FILENAMELENGTH];
                   6336:    char fileresprobcov[FILENAMELENGTH];
                   6337:    char fileresprobcor[FILENAMELENGTH];
                   6338:    double ***varpij;
                   6339: 
                   6340:    strcpy(fileresprob,"PROB_"); 
                   6341:    strcat(fileresprob,fileres);
                   6342:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6343:      printf("Problem with resultfile: %s\n", fileresprob);
                   6344:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6345:    }
                   6346:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6347:    strcat(fileresprobcov,fileresu);
                   6348:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6349:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6350:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6351:    }
                   6352:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6353:    strcat(fileresprobcor,fileresu);
                   6354:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6355:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6356:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6357:    }
                   6358:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6359:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6360:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6361:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6362:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6363:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6364:    pstamp(ficresprob);
                   6365:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6366:    fprintf(ficresprob,"# Age");
                   6367:    pstamp(ficresprobcov);
                   6368:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6369:    fprintf(ficresprobcov,"# Age");
                   6370:    pstamp(ficresprobcor);
                   6371:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6372:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6373: 
                   6374: 
1.222     brouard  6375:    for(i=1; i<=nlstate;i++)
                   6376:      for(j=1; j<=(nlstate+ndeath);j++){
                   6377:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6378:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6379:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6380:      }  
                   6381:    /* fprintf(ficresprob,"\n");
                   6382:       fprintf(ficresprobcov,"\n");
                   6383:       fprintf(ficresprobcor,"\n");
                   6384:    */
                   6385:    xp=vector(1,npar);
                   6386:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6387:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6388:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6389:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6390:    first=1;
                   6391:    fprintf(ficgp,"\n# Routine varprob");
                   6392:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6393:    fprintf(fichtm,"\n");
                   6394: 
1.266     brouard  6395:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6396:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6397:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6398: and drawn. It helps understanding how is the covariance between two incidences.\
                   6399:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6400:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6401: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6402: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6403: standard deviations wide on each axis. <br>\
                   6404:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6405:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6406: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6407: 
1.222     brouard  6408:    cov[1]=1;
                   6409:    /* tj=cptcoveff; */
1.225     brouard  6410:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6411:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6412:    j1=0;
1.224     brouard  6413:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6414:      if  (cptcovn>0) {
                   6415:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6416:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6417:        fprintf(ficresprob, "**********\n#\n");
                   6418:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6419:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6420:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6421:                        
1.222     brouard  6422:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6423:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6424:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6425:                        
                   6426:                        
1.222     brouard  6427:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6428:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6429:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6430:                        
1.222     brouard  6431:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6432:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6433:        fprintf(ficresprobcor, "**********\n#");    
                   6434:        if(invalidvarcomb[j1]){
                   6435:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6436:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6437:         continue;
                   6438:        }
                   6439:      }
                   6440:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6441:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6442:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6443:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6444:      for (age=bage; age<=fage; age ++){ 
                   6445:        cov[2]=age;
                   6446:        if(nagesqr==1)
                   6447:         cov[3]= age*age;
                   6448:        for (k=1; k<=cptcovn;k++) {
                   6449:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6450:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6451:                                                                    * 1  1 1 1 1
                   6452:                                                                    * 2  2 1 1 1
                   6453:                                                                    * 3  1 2 1 1
                   6454:                                                                    */
                   6455:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6456:        }
                   6457:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6458:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6459:        for (k=1; k<=cptcovprod;k++)
                   6460:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6461:                        
                   6462:                        
1.222     brouard  6463:        for(theta=1; theta <=npar; theta++){
                   6464:         for(i=1; i<=npar; i++)
                   6465:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6466:                                
1.222     brouard  6467:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6468:                                
1.222     brouard  6469:         k=0;
                   6470:         for(i=1; i<= (nlstate); i++){
                   6471:           for(j=1; j<=(nlstate+ndeath);j++){
                   6472:             k=k+1;
                   6473:             gp[k]=pmmij[i][j];
                   6474:           }
                   6475:         }
1.220     brouard  6476:                                
1.222     brouard  6477:         for(i=1; i<=npar; i++)
                   6478:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6479:                                
1.222     brouard  6480:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6481:         k=0;
                   6482:         for(i=1; i<=(nlstate); i++){
                   6483:           for(j=1; j<=(nlstate+ndeath);j++){
                   6484:             k=k+1;
                   6485:             gm[k]=pmmij[i][j];
                   6486:           }
                   6487:         }
1.220     brouard  6488:                                
1.222     brouard  6489:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6490:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6491:        }
1.126     brouard  6492: 
1.222     brouard  6493:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6494:         for(theta=1; theta <=npar; theta++)
                   6495:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6496:                        
1.222     brouard  6497:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6498:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6499:                        
1.222     brouard  6500:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6501:                        
1.222     brouard  6502:        k=0;
                   6503:        for(i=1; i<=(nlstate); i++){
                   6504:         for(j=1; j<=(nlstate+ndeath);j++){
                   6505:           k=k+1;
                   6506:           mu[k][(int) age]=pmmij[i][j];
                   6507:         }
                   6508:        }
                   6509:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6510:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6511:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6512:                        
1.222     brouard  6513:        /*printf("\n%d ",(int)age);
                   6514:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6515:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6516:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6517:         }*/
1.220     brouard  6518:                        
1.222     brouard  6519:        fprintf(ficresprob,"\n%d ",(int)age);
                   6520:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6521:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6522:                        
1.222     brouard  6523:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6524:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6525:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6526:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6527:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6528:        }
                   6529:        i=0;
                   6530:        for (k=1; k<=(nlstate);k++){
                   6531:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6532:           i++;
                   6533:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6534:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6535:           for (j=1; j<=i;j++){
                   6536:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6537:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6538:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6539:           }
                   6540:         }
                   6541:        }/* end of loop for state */
                   6542:      } /* end of loop for age */
                   6543:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6544:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6545:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6546:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6547:     
                   6548:      /* Confidence intervalle of pij  */
                   6549:      /*
                   6550:        fprintf(ficgp,"\nunset parametric;unset label");
                   6551:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6552:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6553:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6554:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6555:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6556:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6557:      */
                   6558:                
                   6559:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6560:      first1=1;first2=2;
                   6561:      for (k2=1; k2<=(nlstate);k2++){
                   6562:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6563:         if(l2==k2) continue;
                   6564:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6565:         for (k1=1; k1<=(nlstate);k1++){
                   6566:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6567:             if(l1==k1) continue;
                   6568:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6569:             if(i<=j) continue;
                   6570:             for (age=bage; age<=fage; age ++){ 
                   6571:               if ((int)age %5==0){
                   6572:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6573:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6574:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6575:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6576:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6577:                 c12=cv12/sqrt(v1*v2);
                   6578:                 /* Computing eigen value of matrix of covariance */
                   6579:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6580:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6581:                 if ((lc2 <0) || (lc1 <0) ){
                   6582:                   if(first2==1){
                   6583:                     first1=0;
                   6584:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6585:                   }
                   6586:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6587:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6588:                   /* lc2=fabs(lc2); */
                   6589:                 }
1.220     brouard  6590:                                                                
1.222     brouard  6591:                 /* Eigen vectors */
                   6592:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6593:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6594:                 v21=(lc1-v1)/cv12*v11;
                   6595:                 v12=-v21;
                   6596:                 v22=v11;
                   6597:                 tnalp=v21/v11;
                   6598:                 if(first1==1){
                   6599:                   first1=0;
                   6600:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6601:                 }
                   6602:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6603:                 /*printf(fignu*/
                   6604:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6605:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6606:                 if(first==1){
                   6607:                   first=0;
                   6608:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6609:                   fprintf(ficgp,"\nset parametric;unset label");
                   6610:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6611:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6612:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6613:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6614: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6615:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6616:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6617:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6618:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6619:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6620:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6621:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6622:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6623:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6624:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6625:                 }else{
                   6626:                   first=0;
                   6627:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6628:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6629:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6630:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6631:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6632:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6633:                 }/* if first */
                   6634:               } /* age mod 5 */
                   6635:             } /* end loop age */
                   6636:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6637:             first=1;
                   6638:           } /*l12 */
                   6639:         } /* k12 */
                   6640:        } /*l1 */
                   6641:      }/* k1 */
                   6642:    }  /* loop on combination of covariates j1 */
                   6643:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6644:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6645:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6646:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6647:    free_vector(xp,1,npar);
                   6648:    fclose(ficresprob);
                   6649:    fclose(ficresprobcov);
                   6650:    fclose(ficresprobcor);
                   6651:    fflush(ficgp);
                   6652:    fflush(fichtmcov);
                   6653:  }
1.126     brouard  6654: 
                   6655: 
                   6656: /******************* Printing html file ***********/
1.201     brouard  6657: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6658:                  int lastpass, int stepm, int weightopt, char model[],\
                   6659:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6660:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6661:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6662:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6663:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6664: 
                   6665:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6666:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6667: </ul>");
1.237     brouard  6668:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6669: </ul>", model);
1.214     brouard  6670:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6671:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6672:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6673:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6674:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6675:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6676:    fprintf(fichtm,"\
                   6677:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6678:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6679:    fprintf(fichtm,"\
1.217     brouard  6680:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6681:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6682:    fprintf(fichtm,"\
1.126     brouard  6683:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6684:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6685:    fprintf(fichtm,"\
1.217     brouard  6686:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6687:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6688:    fprintf(fichtm,"\
1.211     brouard  6689:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6690:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6691:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6692:    if(prevfcast==1){
                   6693:      fprintf(fichtm,"\
                   6694:  - Prevalence projections by age and states:                           \
1.201     brouard  6695:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6696:    }
1.126     brouard  6697: 
                   6698: 
1.225     brouard  6699:    m=pow(2,cptcoveff);
1.222     brouard  6700:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6701: 
1.264     brouard  6702:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6703: 
                   6704:    jj1=0;
                   6705: 
                   6706:    fprintf(fichtm," \n<ul>");
                   6707:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6708:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6709:      if(m != 1 && TKresult[nres]!= k1)
                   6710:        continue;
                   6711:      jj1++;
                   6712:      if (cptcovn > 0) {
                   6713:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6714:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6715:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6716:        }
                   6717:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6718:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6719:        }
                   6720:        fprintf(fichtm,"\">");
                   6721:        
                   6722:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6723:        fprintf(fichtm,"************ Results for covariates");
                   6724:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6725:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6726:        }
                   6727:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6728:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6729:        }
                   6730:        if(invalidvarcomb[k1]){
                   6731:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6732:         continue;
                   6733:        }
                   6734:        fprintf(fichtm,"</a></li>");
                   6735:      } /* cptcovn >0 */
                   6736:    }
                   6737:      fprintf(fichtm," \n</ul>");
                   6738: 
1.222     brouard  6739:    jj1=0;
1.237     brouard  6740: 
                   6741:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6742:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6743:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6744:        continue;
1.220     brouard  6745: 
1.222     brouard  6746:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6747:      jj1++;
                   6748:      if (cptcovn > 0) {
1.264     brouard  6749:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6750:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6751:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6752:        }
                   6753:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6754:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6755:        }
                   6756:        fprintf(fichtm,"\"</a>");
                   6757:  
1.222     brouard  6758:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6759:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6760:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6761:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6762:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6763:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6764:        }
1.237     brouard  6765:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6766:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6767:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6768:       }
                   6769:        
1.230     brouard  6770:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6771:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6772:        if(invalidvarcomb[k1]){
                   6773:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6774:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6775:         continue;
                   6776:        }
                   6777:      }
                   6778:      /* aij, bij */
1.259     brouard  6779:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6780: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6781:      /* Pij */
1.241     brouard  6782:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6783: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6784:      /* Quasi-incidences */
                   6785:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6786:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6787:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6788: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6789: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6790:      /* Survival functions (period) in state j */
                   6791:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6792:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6793: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6794:      }
                   6795:      /* State specific survival functions (period) */
                   6796:      for(cpt=1; cpt<=nlstate;cpt++){
                   6797:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6798:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6799:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6800:      }
                   6801:      /* Period (stable) prevalence in each health state */
                   6802:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6803:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6804: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6805:      }
                   6806:      if(backcast==1){
                   6807:        /* Period (stable) back prevalence in each health state */
                   6808:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6809:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6810: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6811:        }
1.217     brouard  6812:      }
1.222     brouard  6813:      if(prevfcast==1){
                   6814:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6815:        for(cpt=1; cpt<=nlstate;cpt++){
1.268     brouard  6816:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.258     brouard  6817: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6818:        }
                   6819:      }
1.268     brouard  6820:      if(backcast==1){
                   6821:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6822:        for(cpt=1; cpt<=nlstate;cpt++){
                   6823:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to stable (mixed) back prevalence in state %d. Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) with weights corresponding to observed prevalence  at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6824: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   6825:        }
                   6826:      }
1.220     brouard  6827:         
1.222     brouard  6828:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6829:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6830: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6831:      }
                   6832:      /* } /\* end i1 *\/ */
                   6833:    }/* End k1 */
                   6834:    fprintf(fichtm,"</ul>");
1.126     brouard  6835: 
1.222     brouard  6836:    fprintf(fichtm,"\
1.126     brouard  6837: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6838:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6839:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6840: But because parameters are usually highly correlated (a higher incidence of disability \
                   6841: and a higher incidence of recovery can give very close observed transition) it might \
                   6842: be very useful to look not only at linear confidence intervals estimated from the \
                   6843: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6844: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6845: covariance matrix of the one-step probabilities. \
                   6846: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6847: 
1.222     brouard  6848:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6849:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6850:    fprintf(fichtm,"\
1.126     brouard  6851:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6852:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6853: 
1.222     brouard  6854:    fprintf(fichtm,"\
1.126     brouard  6855:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6856:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6857:    fprintf(fichtm,"\
1.126     brouard  6858:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6859:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6860:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6861:    fprintf(fichtm,"\
1.126     brouard  6862:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6863:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6864:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6865:    fprintf(fichtm,"\
1.128     brouard  6866:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6867:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6868:    fprintf(fichtm,"\
1.128     brouard  6869:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6870:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6871:    fprintf(fichtm,"\
1.126     brouard  6872:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6873:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6874: 
                   6875: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6876: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6877: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6878: /*     <br>",fileres,fileres,fileres,fileres); */
                   6879: /*  else  */
                   6880: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6881:    fflush(fichtm);
                   6882:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6883: 
1.225     brouard  6884:    m=pow(2,cptcoveff);
1.222     brouard  6885:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6886: 
1.222     brouard  6887:    jj1=0;
1.237     brouard  6888: 
1.241     brouard  6889:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6890:    for(k1=1; k1<=m;k1++){
1.253     brouard  6891:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6892:        continue;
1.222     brouard  6893:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6894:      jj1++;
1.126     brouard  6895:      if (cptcovn > 0) {
                   6896:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6897:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6898:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6899:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6900:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6901:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6902:       }
                   6903: 
1.126     brouard  6904:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6905: 
1.222     brouard  6906:        if(invalidvarcomb[k1]){
                   6907:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6908:         continue;
                   6909:        }
1.126     brouard  6910:      }
                   6911:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6912:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6913: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6914: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6915:      }
                   6916:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6917: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6918: true period expectancies (those weighted with period prevalences are also\
                   6919:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6920:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6921: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6922:      /* } /\* end i1 *\/ */
                   6923:    }/* End k1 */
1.241     brouard  6924:   }/* End nres */
1.222     brouard  6925:    fprintf(fichtm,"</ul>");
                   6926:    fflush(fichtm);
1.126     brouard  6927: }
                   6928: 
                   6929: /******************* Gnuplot file **************/
1.270     brouard  6930: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6931: 
                   6932:   char dirfileres[132],optfileres[132];
1.264     brouard  6933:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6934:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6935:   int lv=0, vlv=0, kl=0;
1.130     brouard  6936:   int ng=0;
1.201     brouard  6937:   int vpopbased;
1.223     brouard  6938:   int ioffset; /* variable offset for columns */
1.270     brouard  6939:   int iyearc=1; /* variable column for year of projection  */
                   6940:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  6941:   int nres=0; /* Index of resultline */
1.266     brouard  6942:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6943: 
1.126     brouard  6944: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6945: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6946: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6947: /*   } */
                   6948: 
                   6949:   /*#ifdef windows */
                   6950:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6951:   /*#endif */
1.225     brouard  6952:   m=pow(2,cptcoveff);
1.126     brouard  6953: 
1.202     brouard  6954:   /* Contribution to likelihood */
                   6955:   /* Plot the probability implied in the likelihood */
1.223     brouard  6956:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6957:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6958:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6959:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6960: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6961:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6962: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6963:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6964:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6965:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6966:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6967:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6968:   for (i=1; i<= nlstate ; i ++) {
                   6969:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6970:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6971:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6972:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6973:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6974:     }
                   6975:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6976:   }
                   6977:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6978:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6979:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6980:   fprintf(ficgp,"\nset out;unset log\n");
                   6981:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6982: 
1.126     brouard  6983:   strcpy(dirfileres,optionfilefiname);
                   6984:   strcpy(optfileres,"vpl");
1.223     brouard  6985:   /* 1eme*/
1.238     brouard  6986:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6987:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6988:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6989:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6990:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6991:          continue;
                   6992:        /* We are interested in selected combination by the resultline */
1.246     brouard  6993:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6994:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  6995:        strcpy(gplotlabel,"(");
1.238     brouard  6996:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6997:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6998:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6999:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7000:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7001:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7002:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7003:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7004:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7005:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7006:        }
                   7007:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7008:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7009:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7010:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7011:        }
                   7012:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7013:        /* printf("\n#\n"); */
1.238     brouard  7014:        fprintf(ficgp,"\n#\n");
                   7015:        if(invalidvarcomb[k1]){
1.260     brouard  7016:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7017:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7018:          continue;
                   7019:        }
1.235     brouard  7020:       
1.241     brouard  7021:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7022:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7023:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7024:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7025:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7026:       /* k1-1 error should be nres-1*/
1.238     brouard  7027:        for (i=1; i<= nlstate ; i ++) {
                   7028:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7029:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7030:        }
1.260     brouard  7031:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7032:        for (i=1; i<= nlstate ; i ++) {
                   7033:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7034:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7035:        } 
1.260     brouard  7036:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7037:        for (i=1; i<= nlstate ; i ++) {
                   7038:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7039:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7040:        }  
1.265     brouard  7041:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7042:        
                   7043:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7044:         if(cptcoveff ==0){
1.271   ! brouard  7045:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7046:        }else{
                   7047:          kl=0;
                   7048:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7049:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7050:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7051:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7052:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7053:            vlv= nbcode[Tvaraff[k]][lv];
                   7054:            kl++;
                   7055:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7056:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7057:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7058:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7059:            if(k==cptcoveff){
                   7060:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7061:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7062:            }else{
                   7063:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7064:              kl++;
                   7065:            }
                   7066:          } /* end covariate */
                   7067:        } /* end if no covariate */
                   7068: 
1.238     brouard  7069:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7070:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7071:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7072:          if(cptcoveff ==0){
1.245     brouard  7073:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7074:          }else{
                   7075:            kl=0;
                   7076:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7077:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7078:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7079:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7080:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7081:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7082:              kl++;
1.238     brouard  7083:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7084:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7085:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7086:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7087:              if(k==cptcoveff){
1.245     brouard  7088:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7089:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7090:              }else{
                   7091:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7092:                kl++;
                   7093:              }
                   7094:            } /* end covariate */
                   7095:          } /* end if no covariate */
1.268     brouard  7096:          if(backcast == 1){
                   7097:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7098:            /* k1-1 error should be nres-1*/
                   7099:            for (i=1; i<= nlstate ; i ++) {
                   7100:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7101:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7102:            }
1.271   ! brouard  7103:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7104:            for (i=1; i<= nlstate ; i ++) {
                   7105:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7106:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7107:            } 
1.271   ! brouard  7108:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 6,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7109:            for (i=1; i<= nlstate ; i ++) {
                   7110:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7111:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7112:            } 
1.271   ! brouard  7113:            fprintf(ficgp,"\" t\"\" w l lt 6");
1.268     brouard  7114:          } /* end if backprojcast */
1.238     brouard  7115:        } /* end if backcast */
1.264     brouard  7116:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7117:       } /* nres */
1.201     brouard  7118:     } /* k1 */
                   7119:   } /* cpt */
1.235     brouard  7120: 
                   7121:   
1.126     brouard  7122:   /*2 eme*/
1.238     brouard  7123:   for (k1=1; k1<= m ; k1 ++){  
                   7124:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7125:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7126:        continue;
                   7127:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7128:       strcpy(gplotlabel,"(");
1.238     brouard  7129:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7130:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7131:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7132:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7133:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7134:        vlv= nbcode[Tvaraff[k]][lv];
                   7135:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7136:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7137:       }
1.237     brouard  7138:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7139:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7140:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7141:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7142:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7143:       }
1.264     brouard  7144:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7145:       fprintf(ficgp,"\n#\n");
1.223     brouard  7146:       if(invalidvarcomb[k1]){
                   7147:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7148:        continue;
                   7149:       }
1.219     brouard  7150:                        
1.241     brouard  7151:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7152:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7153:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7154:        if(vpopbased==0){
1.238     brouard  7155:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7156:        }else
1.238     brouard  7157:          fprintf(ficgp,"\nreplot ");
                   7158:        for (i=1; i<= nlstate+1 ; i ++) {
                   7159:          k=2*i;
1.261     brouard  7160:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7161:          for (j=1; j<= nlstate+1 ; j ++) {
                   7162:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7163:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7164:          }   
                   7165:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7166:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7167:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7168:          for (j=1; j<= nlstate+1 ; j ++) {
                   7169:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7170:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7171:          }   
                   7172:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7173:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7174:          for (j=1; j<= nlstate+1 ; j ++) {
                   7175:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7176:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7177:          }   
                   7178:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7179:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7180:        } /* state */
                   7181:       } /* vpopbased */
1.264     brouard  7182:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7183:     } /* end nres */
                   7184:   } /* k1 end 2 eme*/
                   7185:        
                   7186:        
                   7187:   /*3eme*/
                   7188:   for (k1=1; k1<= m ; k1 ++){
                   7189:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7190:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7191:        continue;
                   7192: 
                   7193:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7194:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7195:        strcpy(gplotlabel,"(");
1.238     brouard  7196:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7197:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7198:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7199:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7200:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7201:          vlv= nbcode[Tvaraff[k]][lv];
                   7202:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7203:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7204:        }
                   7205:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7206:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7207:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7208:        }       
1.264     brouard  7209:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7210:        fprintf(ficgp,"\n#\n");
                   7211:        if(invalidvarcomb[k1]){
                   7212:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7213:          continue;
                   7214:        }
                   7215:                        
                   7216:        /*       k=2+nlstate*(2*cpt-2); */
                   7217:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7218:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7219:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7220:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7221: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7222:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7223:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7224:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7225:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7226:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7227:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7228:                                
1.238     brouard  7229:        */
                   7230:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7231:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7232:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7233:                                
1.238     brouard  7234:        } 
1.261     brouard  7235:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7236:       }
1.264     brouard  7237:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7238:     } /* end nres */
                   7239:   } /* end kl 3eme */
1.126     brouard  7240:   
1.223     brouard  7241:   /* 4eme */
1.201     brouard  7242:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7243:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7244:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7245:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7246:        continue;
1.238     brouard  7247:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7248:        strcpy(gplotlabel,"(");
1.238     brouard  7249:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7250:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7251:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7252:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7253:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7254:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7255:          vlv= nbcode[Tvaraff[k]][lv];
                   7256:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7257:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7258:        }
                   7259:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7260:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7261:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7262:        }       
1.264     brouard  7263:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7264:        fprintf(ficgp,"\n#\n");
                   7265:        if(invalidvarcomb[k1]){
                   7266:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7267:          continue;
1.223     brouard  7268:        }
1.238     brouard  7269:       
1.241     brouard  7270:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7271:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7272:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7273: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7274:        k=3;
                   7275:        for (i=1; i<= nlstate ; i ++){
                   7276:          if(i==1){
                   7277:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7278:          }else{
                   7279:            fprintf(ficgp,", '' ");
                   7280:          }
                   7281:          l=(nlstate+ndeath)*(i-1)+1;
                   7282:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7283:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7284:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7285:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7286:        } /* nlstate */
1.264     brouard  7287:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7288:       } /* end cpt state*/ 
                   7289:     } /* end nres */
                   7290:   } /* end covariate k1 */  
                   7291: 
1.220     brouard  7292: /* 5eme */
1.201     brouard  7293:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7294:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7295:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7296:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7297:        continue;
1.238     brouard  7298:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7299:        strcpy(gplotlabel,"(");
1.238     brouard  7300:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7301:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7302:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7303:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7304:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7305:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7306:          vlv= nbcode[Tvaraff[k]][lv];
                   7307:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7308:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7309:        }
                   7310:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7311:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7312:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7313:        }       
1.264     brouard  7314:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7315:        fprintf(ficgp,"\n#\n");
                   7316:        if(invalidvarcomb[k1]){
                   7317:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7318:          continue;
                   7319:        }
1.227     brouard  7320:       
1.241     brouard  7321:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7322:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7323:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7324: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7325:        k=3;
                   7326:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7327:          if(j==1)
                   7328:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7329:          else
                   7330:            fprintf(ficgp,", '' ");
                   7331:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7332:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7333:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7334:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7335:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7336:        } /* nlstate */
                   7337:        fprintf(ficgp,", '' ");
                   7338:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7339:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7340:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7341:          if(j < nlstate)
                   7342:            fprintf(ficgp,"$%d +",k+l);
                   7343:          else
                   7344:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7345:        }
1.264     brouard  7346:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7347:       } /* end cpt state*/ 
                   7348:     } /* end covariate */  
                   7349:   } /* end nres */
1.227     brouard  7350:   
1.220     brouard  7351: /* 6eme */
1.202     brouard  7352:   /* CV preval stable (period) for each covariate */
1.237     brouard  7353:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7354:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7355:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7356:       continue;
1.255     brouard  7357:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7358:       strcpy(gplotlabel,"(");      
1.211     brouard  7359:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7360:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7361:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7362:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7363:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7364:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7365:        vlv= nbcode[Tvaraff[k]][lv];
                   7366:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7367:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7368:       }
1.237     brouard  7369:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7370:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7371:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7372:       }        
1.264     brouard  7373:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7374:       fprintf(ficgp,"\n#\n");
1.223     brouard  7375:       if(invalidvarcomb[k1]){
1.227     brouard  7376:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7377:        continue;
1.223     brouard  7378:       }
1.227     brouard  7379:       
1.241     brouard  7380:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7381:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7382:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7383: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7384:       k=3; /* Offset */
1.255     brouard  7385:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7386:        if(i==1)
                   7387:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7388:        else
                   7389:          fprintf(ficgp,", '' ");
1.255     brouard  7390:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7391:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7392:        for (j=2; j<= nlstate ; j ++)
                   7393:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7394:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7395:       } /* nlstate */
1.264     brouard  7396:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7397:     } /* end cpt state*/ 
                   7398:   } /* end covariate */  
1.227     brouard  7399:   
                   7400:   
1.220     brouard  7401: /* 7eme */
1.218     brouard  7402:   if(backcast == 1){
1.217     brouard  7403:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7404:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7405:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7406:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7407:        continue;
1.268     brouard  7408:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7409:        strcpy(gplotlabel,"(");      
                   7410:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7411:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7412:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7413:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7414:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7415:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7416:          vlv= nbcode[Tvaraff[k]][lv];
                   7417:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7418:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7419:        }
1.237     brouard  7420:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7421:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7422:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7423:        }       
1.264     brouard  7424:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7425:        fprintf(ficgp,"\n#\n");
                   7426:        if(invalidvarcomb[k1]){
                   7427:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7428:          continue;
                   7429:        }
                   7430:        
1.241     brouard  7431:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7432:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7433:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7434: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7435:        k=3; /* Offset */
1.268     brouard  7436:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7437:          if(i==1)
                   7438:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7439:          else
                   7440:            fprintf(ficgp,", '' ");
                   7441:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7442:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7443:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7444:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7445:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7446:          /* for (j=2; j<= nlstate ; j ++) */
                   7447:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7448:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7449:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7450:        } /* nlstate */
1.264     brouard  7451:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7452:       } /* end cpt state*/ 
                   7453:     } /* end covariate */  
                   7454:   } /* End if backcast */
                   7455:   
1.223     brouard  7456:   /* 8eme */
1.218     brouard  7457:   if(prevfcast==1){
                   7458:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7459:     
1.237     brouard  7460:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7461:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7462:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7463:        continue;
1.211     brouard  7464:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7465:        strcpy(gplotlabel,"(");      
1.227     brouard  7466:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7467:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7468:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7469:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7470:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7471:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7472:          vlv= nbcode[Tvaraff[k]][lv];
                   7473:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7474:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7475:        }
1.237     brouard  7476:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7477:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7478:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7479:        }       
1.264     brouard  7480:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7481:        fprintf(ficgp,"\n#\n");
                   7482:        if(invalidvarcomb[k1]){
                   7483:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7484:          continue;
                   7485:        }
                   7486:        
                   7487:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7488:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7489:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7490:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7491: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7492: 
                   7493:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7494:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7495:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7496:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7497:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7498:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7499:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7500:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7501:          if(i==istart){
1.227     brouard  7502:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7503:          }else{
                   7504:            fprintf(ficgp,",\\\n '' ");
                   7505:          }
                   7506:          if(cptcoveff ==0){ /* No covariate */
                   7507:            ioffset=2; /* Age is in 2 */
                   7508:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7509:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7510:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7511:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7512:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7513:            if(i==nlstate+1){
1.270     brouard  7514:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7515:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7516:              fprintf(ficgp,",\\\n '' ");
                   7517:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7518:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7519:                     offyear,                           \
1.268     brouard  7520:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7521:            }else
1.227     brouard  7522:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7523:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7524:          }else{ /* more than 2 covariates */
1.270     brouard  7525:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7526:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7527:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7528:            iyearc=ioffset-1;
                   7529:            iagec=ioffset;
1.227     brouard  7530:            fprintf(ficgp," u %d:(",ioffset); 
                   7531:            kl=0;
                   7532:            strcpy(gplotcondition,"(");
                   7533:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7534:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7535:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7536:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7537:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7538:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7539:              kl++;
                   7540:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7541:              kl++;
                   7542:              if(k <cptcoveff && cptcoveff>1)
                   7543:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7544:            }
                   7545:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7546:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7547:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7548:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7549:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7550:            if(i==nlstate+1){
1.270     brouard  7551:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7552:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7553:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7554:              fprintf(ficgp," u %d:(",iagec); 
                   7555:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7556:                      iyearc, iagec, offyear,                           \
                   7557:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7558: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7559:            }else{
                   7560:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7561:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7562:            }
                   7563:          } /* end if covariate */
                   7564:        } /* nlstate */
1.264     brouard  7565:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7566:       } /* end cpt state*/
                   7567:     } /* end covariate */
                   7568:   } /* End if prevfcast */
1.227     brouard  7569:   
1.268     brouard  7570:   if(backcast==1){
                   7571:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7572:     
                   7573:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7574:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7575:       if(m != 1 && TKresult[nres]!= k1)
                   7576:        continue;
                   7577:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7578:        strcpy(gplotlabel,"(");      
                   7579:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7580:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7581:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7582:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7583:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7584:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7585:          vlv= nbcode[Tvaraff[k]][lv];
                   7586:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7587:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7588:        }
                   7589:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7590:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7591:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7592:        }       
                   7593:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7594:        fprintf(ficgp,"\n#\n");
                   7595:        if(invalidvarcomb[k1]){
                   7596:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7597:          continue;
                   7598:        }
                   7599:        
                   7600:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7601:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7602:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7603:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7604: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7605: 
                   7606:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7607:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7608:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7609:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7610:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7611:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7612:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7613:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7614:          if(i==istart){
                   7615:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7616:          }else{
                   7617:            fprintf(ficgp,",\\\n '' ");
                   7618:          }
                   7619:          if(cptcoveff ==0){ /* No covariate */
                   7620:            ioffset=2; /* Age is in 2 */
                   7621:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7622:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7623:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7624:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7625:            fprintf(ficgp," u %d:(", ioffset); 
                   7626:            if(i==nlstate+1){
1.270     brouard  7627:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7628:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7629:              fprintf(ficgp,",\\\n '' ");
                   7630:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7631:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7632:                     offbyear,                          \
                   7633:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7634:            }else
                   7635:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7636:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7637:          }else{ /* more than 2 covariates */
1.270     brouard  7638:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7639:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7640:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7641:            iyearc=ioffset-1;
                   7642:            iagec=ioffset;
1.268     brouard  7643:            fprintf(ficgp," u %d:(",ioffset); 
                   7644:            kl=0;
                   7645:            strcpy(gplotcondition,"(");
                   7646:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7647:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7648:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7649:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7650:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7651:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7652:              kl++;
                   7653:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7654:              kl++;
                   7655:              if(k <cptcoveff && cptcoveff>1)
                   7656:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7657:            }
                   7658:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7659:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7660:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7661:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7662:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7663:            if(i==nlstate+1){
1.270     brouard  7664:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7665:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7666:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7667:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7668:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7669:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7670:                      iyearc,iagec,offbyear,                            \
                   7671:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7672: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7673:            }else{
                   7674:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7675:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7676:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7677:            }
                   7678:          } /* end if covariate */
                   7679:        } /* nlstate */
                   7680:        fprintf(ficgp,"\nset out; unset label;\n");
                   7681:       } /* end cpt state*/
                   7682:     } /* end covariate */
                   7683:   } /* End if backcast */
                   7684:   
1.227     brouard  7685:   
1.238     brouard  7686:   /* 9eme writing MLE parameters */
                   7687:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7688:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7689:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7690:     for(k=1; k <=(nlstate+ndeath); k++){
                   7691:       if (k != i) {
1.227     brouard  7692:        fprintf(ficgp,"#   current state %d\n",k);
                   7693:        for(j=1; j <=ncovmodel; j++){
                   7694:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7695:          jk++; 
                   7696:        }
                   7697:        fprintf(ficgp,"\n");
1.126     brouard  7698:       }
                   7699:     }
1.223     brouard  7700:   }
1.187     brouard  7701:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7702:   
1.145     brouard  7703:   /*goto avoid;*/
1.238     brouard  7704:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7705:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7706:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7707:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7708:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7709:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7710:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7711:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7712:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7713:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7714:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7715:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7716:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7717:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7718:   fprintf(ficgp,"#\n");
1.223     brouard  7719:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7720:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7721:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7722:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7723:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7724:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7725:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7726:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7727:        continue;
1.264     brouard  7728:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7729:       strcpy(gplotlabel,"(");
                   7730:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7731:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7732:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7733:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7734:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7735:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7736:        vlv= nbcode[Tvaraff[k]][lv];
                   7737:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7738:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7739:       }
1.237     brouard  7740:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7741:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7742:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7743:       }        
1.264     brouard  7744:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7745:       fprintf(ficgp,"\n#\n");
1.264     brouard  7746:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7747:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7748:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7749:       if (ng==1){
                   7750:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7751:        fprintf(ficgp,"\nunset log y");
                   7752:       }else if (ng==2){
                   7753:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7754:        fprintf(ficgp,"\nset log y");
                   7755:       }else if (ng==3){
                   7756:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7757:        fprintf(ficgp,"\nset log y");
                   7758:       }else
                   7759:        fprintf(ficgp,"\nunset title ");
                   7760:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7761:       i=1;
                   7762:       for(k2=1; k2<=nlstate; k2++) {
                   7763:        k3=i;
                   7764:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7765:          if (k != k2){
                   7766:            switch( ng) {
                   7767:            case 1:
                   7768:              if(nagesqr==0)
                   7769:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7770:              else /* nagesqr =1 */
                   7771:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7772:              break;
                   7773:            case 2: /* ng=2 */
                   7774:              if(nagesqr==0)
                   7775:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7776:              else /* nagesqr =1 */
                   7777:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7778:              break;
                   7779:            case 3:
                   7780:              if(nagesqr==0)
                   7781:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7782:              else /* nagesqr =1 */
                   7783:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7784:              break;
                   7785:            }
                   7786:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7787:            ijp=1; /* product no age */
                   7788:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7789:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7790:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7791:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7792:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7793:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7794:                    if(DummyV[j]==0){
                   7795:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7796:                    }else{ /* quantitative */
                   7797:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7798:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7799:                    }
                   7800:                    ij++;
1.237     brouard  7801:                  }
1.268     brouard  7802:                } 
                   7803:              }else if(cptcovprod >0){
                   7804:                if(j==Tprod[ijp]) { /* */ 
                   7805:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7806:                  if(ijp <=cptcovprod) { /* Product */
                   7807:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7808:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7809:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7810:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7811:                      }else{ /* Vn is dummy and Vm is quanti */
                   7812:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7813:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7814:                      }
                   7815:                    }else{ /* Vn*Vm Vn is quanti */
                   7816:                      if(DummyV[Tvard[ijp][2]]==0){
                   7817:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7818:                      }else{ /* Both quanti */
                   7819:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7820:                      }
1.237     brouard  7821:                    }
1.268     brouard  7822:                    ijp++;
1.237     brouard  7823:                  }
1.268     brouard  7824:                } /* end Tprod */
1.237     brouard  7825:              } else{  /* simple covariate */
1.264     brouard  7826:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7827:                if(Dummy[j]==0){
                   7828:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7829:                }else{ /* quantitative */
                   7830:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7831:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7832:                }
1.237     brouard  7833:              } /* end simple */
                   7834:            } /* end j */
1.223     brouard  7835:          }else{
                   7836:            i=i-ncovmodel;
                   7837:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7838:              fprintf(ficgp," (1.");
                   7839:          }
1.227     brouard  7840:          
1.223     brouard  7841:          if(ng != 1){
                   7842:            fprintf(ficgp,")/(1");
1.227     brouard  7843:            
1.264     brouard  7844:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7845:              if(nagesqr==0)
1.264     brouard  7846:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7847:              else /* nagesqr =1 */
1.264     brouard  7848:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7849:               
1.223     brouard  7850:              ij=1;
                   7851:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7852:                 if(cptcovage >0){ 
                   7853:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7854:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7855:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7856:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7857:                       ij++;
                   7858:                     }
                   7859:                   }
                   7860:                 }else
                   7861:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7862:              }
                   7863:              fprintf(ficgp,")");
                   7864:            }
                   7865:            fprintf(ficgp,")");
                   7866:            if(ng ==2)
                   7867:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7868:            else /* ng= 3 */
                   7869:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7870:          }else{ /* end ng <> 1 */
                   7871:            if( k !=k2) /* logit p11 is hard to draw */
                   7872:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7873:          }
                   7874:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7875:            fprintf(ficgp,",");
                   7876:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7877:            fprintf(ficgp,",");
                   7878:          i=i+ncovmodel;
                   7879:        } /* end k */
                   7880:       } /* end k2 */
1.264     brouard  7881:       fprintf(ficgp,"\n set out; unset label;\n");
                   7882:     } /* end k1 */
1.223     brouard  7883:   } /* end ng */
                   7884:   /* avoid: */
                   7885:   fflush(ficgp); 
1.126     brouard  7886: }  /* end gnuplot */
                   7887: 
                   7888: 
                   7889: /*************** Moving average **************/
1.219     brouard  7890: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7891:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7892:    
1.222     brouard  7893:    int i, cpt, cptcod;
                   7894:    int modcovmax =1;
                   7895:    int mobilavrange, mob;
                   7896:    int iage=0;
                   7897: 
1.266     brouard  7898:    double sum=0., sumr=0.;
1.222     brouard  7899:    double age;
1.266     brouard  7900:    double *sumnewp, *sumnewm, *sumnewmr;
                   7901:    double *agemingood, *agemaxgood; 
                   7902:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7903:   
                   7904:   
1.225     brouard  7905:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7906:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7907: 
                   7908:    sumnewp = vector(1,ncovcombmax);
                   7909:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7910:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7911:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7912:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7913:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7914:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7915: 
                   7916:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7917:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7918:      sumnewp[cptcod]=0.;
1.266     brouard  7919:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7920:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7921:    }
                   7922:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7923:   
1.266     brouard  7924:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7925:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7926:      else mobilavrange=mobilav;
                   7927:      for (age=bage; age<=fage; age++)
                   7928:        for (i=1; i<=nlstate;i++)
                   7929:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7930:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7931:      /* We keep the original values on the extreme ages bage, fage and for 
                   7932:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7933:        we use a 5 terms etc. until the borders are no more concerned. 
                   7934:      */ 
                   7935:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7936:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7937:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7938:           sumnewm[cptcod]=0.;
                   7939:           for (i=1; i<=nlstate;i++){
1.222     brouard  7940:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7941:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7942:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7943:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7944:             }
                   7945:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7946:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7947:           } /* end i */
                   7948:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7949:         } /* end cptcod */
1.222     brouard  7950:        }/* end age */
                   7951:      }/* end mob */
1.266     brouard  7952:    }else{
                   7953:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7954:      return -1;
1.266     brouard  7955:    }
                   7956: 
                   7957:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7958:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7959:      if(invalidvarcomb[cptcod]){
                   7960:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7961:        continue;
                   7962:      }
1.219     brouard  7963: 
1.266     brouard  7964:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7965:        sumnewm[cptcod]=0.;
                   7966:        sumnewmr[cptcod]=0.;
                   7967:        for (i=1; i<=nlstate;i++){
                   7968:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7969:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7970:        }
                   7971:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7972:         agemingoodr[cptcod]=age;
                   7973:        }
                   7974:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7975:           agemingood[cptcod]=age;
                   7976:        }
                   7977:      } /* age */
                   7978:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  7979:        sumnewm[cptcod]=0.;
1.266     brouard  7980:        sumnewmr[cptcod]=0.;
1.222     brouard  7981:        for (i=1; i<=nlstate;i++){
                   7982:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  7983:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7984:        }
                   7985:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7986:         agemaxgoodr[cptcod]=age;
1.222     brouard  7987:        }
                   7988:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  7989:         agemaxgood[cptcod]=age;
                   7990:        }
                   7991:      } /* age */
                   7992:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   7993:      /* but they will change */
                   7994:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   7995:        sumnewm[cptcod]=0.;
                   7996:        sumnewmr[cptcod]=0.;
                   7997:        for (i=1; i<=nlstate;i++){
                   7998:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7999:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8000:        }
                   8001:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8002:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8003:           agemaxgoodr[cptcod]=age;  /* age min */
                   8004:           for (i=1; i<=nlstate;i++)
                   8005:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8006:         }else{ /* bad we change the value with the values of good ages */
                   8007:           for (i=1; i<=nlstate;i++){
                   8008:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8009:           } /* i */
                   8010:         } /* end bad */
                   8011:        }else{
                   8012:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8013:           agemaxgood[cptcod]=age;
                   8014:         }else{ /* bad we change the value with the values of good ages */
                   8015:           for (i=1; i<=nlstate;i++){
                   8016:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8017:           } /* i */
                   8018:         } /* end bad */
                   8019:        }/* end else */
                   8020:        sum=0.;sumr=0.;
                   8021:        for (i=1; i<=nlstate;i++){
                   8022:         sum+=mobaverage[(int)age][i][cptcod];
                   8023:         sumr+=probs[(int)age][i][cptcod];
                   8024:        }
                   8025:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8026:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8027:        } /* end bad */
                   8028:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8029:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8030:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8031:        } /* end bad */
                   8032:      }/* age */
1.266     brouard  8033: 
                   8034:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8035:        sumnewm[cptcod]=0.;
1.266     brouard  8036:        sumnewmr[cptcod]=0.;
1.222     brouard  8037:        for (i=1; i<=nlstate;i++){
                   8038:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8039:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8040:        } 
                   8041:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8042:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8043:           agemingoodr[cptcod]=age;
                   8044:           for (i=1; i<=nlstate;i++)
                   8045:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8046:         }else{ /* bad we change the value with the values of good ages */
                   8047:           for (i=1; i<=nlstate;i++){
                   8048:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8049:           } /* i */
                   8050:         } /* end bad */
                   8051:        }else{
                   8052:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8053:           agemingood[cptcod]=age;
                   8054:         }else{ /* bad */
                   8055:           for (i=1; i<=nlstate;i++){
                   8056:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8057:           } /* i */
                   8058:         } /* end bad */
                   8059:        }/* end else */
                   8060:        sum=0.;sumr=0.;
                   8061:        for (i=1; i<=nlstate;i++){
                   8062:         sum+=mobaverage[(int)age][i][cptcod];
                   8063:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8064:        }
1.266     brouard  8065:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8066:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8067:        } /* end bad */
                   8068:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8069:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8070:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8071:        } /* end bad */
                   8072:      }/* age */
1.266     brouard  8073: 
1.222     brouard  8074:                
                   8075:      for (age=bage; age<=fage; age++){
1.235     brouard  8076:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8077:        sumnewp[cptcod]=0.;
                   8078:        sumnewm[cptcod]=0.;
                   8079:        for (i=1; i<=nlstate;i++){
                   8080:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8081:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8082:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8083:        }
                   8084:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8085:      }
                   8086:      /* printf("\n"); */
                   8087:      /* } */
1.266     brouard  8088: 
1.222     brouard  8089:      /* brutal averaging */
1.266     brouard  8090:      /* for (i=1; i<=nlstate;i++){ */
                   8091:      /*   for (age=1; age<=bage; age++){ */
                   8092:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8093:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8094:      /*   }     */
                   8095:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8096:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8097:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8098:      /*   } */
                   8099:      /* } /\* end i status *\/ */
                   8100:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8101:      /*   for (age=1; age<=AGESUP; age++){ */
                   8102:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8103:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8104:      /*   } */
                   8105:      /* } */
1.222     brouard  8106:    }/* end cptcod */
1.266     brouard  8107:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8108:    free_vector(agemaxgood,1, ncovcombmax);
                   8109:    free_vector(agemingood,1, ncovcombmax);
                   8110:    free_vector(agemingoodr,1, ncovcombmax);
                   8111:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8112:    free_vector(sumnewm,1, ncovcombmax);
                   8113:    free_vector(sumnewp,1, ncovcombmax);
                   8114:    return 0;
                   8115:  }/* End movingaverage */
1.218     brouard  8116:  
1.126     brouard  8117: 
                   8118: /************** Forecasting ******************/
1.269     brouard  8119:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8120:   /* proj1, year, month, day of starting projection 
                   8121:      agemin, agemax range of age
                   8122:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8123:      anproj2 year of en of projection (same day and month as proj1).
                   8124:   */
1.267     brouard  8125:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8126:   double agec; /* generic age */
                   8127:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8128:   double *popeffectif,*popcount;
                   8129:   double ***p3mat;
1.218     brouard  8130:   /* double ***mobaverage; */
1.126     brouard  8131:   char fileresf[FILENAMELENGTH];
                   8132: 
                   8133:   agelim=AGESUP;
1.211     brouard  8134:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8135:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8136:      We still use firstpass and lastpass as another selection.
                   8137:   */
1.214     brouard  8138:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8139:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8140:  
1.201     brouard  8141:   strcpy(fileresf,"F_"); 
                   8142:   strcat(fileresf,fileresu);
1.126     brouard  8143:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8144:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8145:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8146:   }
1.235     brouard  8147:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8148:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8149: 
1.225     brouard  8150:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8151: 
                   8152: 
                   8153:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8154:   if (stepm<=12) stepsize=1;
                   8155:   if(estepm < stepm){
                   8156:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8157:   }
1.270     brouard  8158:   else{
                   8159:     hstepm=estepm;   
                   8160:   }
                   8161:   if(estepm > stepm){ /* Yes every two year */
                   8162:     stepsize=2;
                   8163:   }
1.126     brouard  8164: 
                   8165:   hstepm=hstepm/stepm; 
                   8166:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8167:                                fractional in yp1 */
                   8168:   anprojmean=yp;
                   8169:   yp2=modf((yp1*12),&yp);
                   8170:   mprojmean=yp;
                   8171:   yp1=modf((yp2*30.5),&yp);
                   8172:   jprojmean=yp;
                   8173:   if(jprojmean==0) jprojmean=1;
                   8174:   if(mprojmean==0) jprojmean=1;
                   8175: 
1.227     brouard  8176:   i1=pow(2,cptcoveff);
1.126     brouard  8177:   if (cptcovn < 1){i1=1;}
                   8178:   
                   8179:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8180:   
                   8181:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8182:   
1.126     brouard  8183: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8184:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8185:   for(k=1; k<=i1;k++){
1.253     brouard  8186:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8187:       continue;
1.227     brouard  8188:     if(invalidvarcomb[k]){
                   8189:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8190:       continue;
                   8191:     }
                   8192:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8193:     for(j=1;j<=cptcoveff;j++) {
                   8194:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8195:     }
1.235     brouard  8196:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8197:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8198:     }
1.227     brouard  8199:     fprintf(ficresf," yearproj age");
                   8200:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8201:       for(i=1; i<=nlstate;i++)               
                   8202:        fprintf(ficresf," p%d%d",i,j);
                   8203:       fprintf(ficresf," wp.%d",j);
                   8204:     }
                   8205:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8206:       fprintf(ficresf,"\n");
                   8207:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8208:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8209:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8210:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8211:        nhstepm = nhstepm/hstepm; 
                   8212:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8213:        oldm=oldms;savm=savms;
1.268     brouard  8214:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8215:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8216:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8217:        for (h=0; h<=nhstepm; h++){
                   8218:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8219:            break;
                   8220:          }
                   8221:        }
                   8222:        fprintf(ficresf,"\n");
                   8223:        for(j=1;j<=cptcoveff;j++) 
                   8224:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8225:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8226:        
                   8227:        for(j=1; j<=nlstate+ndeath;j++) {
                   8228:          ppij=0.;
                   8229:          for(i=1; i<=nlstate;i++) {
                   8230:            /* if (mobilav>=1)  */
1.269     brouard  8231:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8232:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8233:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8234:            /* } */
                   8235:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8236:          } /* end i */
                   8237:          fprintf(ficresf," %.3f", ppij);
                   8238:        }/* end j */
1.227     brouard  8239:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8240:       } /* end agec */
1.266     brouard  8241:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8242:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8243:     } /* end yearp */
                   8244:   } /* end  k */
1.219     brouard  8245:        
1.126     brouard  8246:   fclose(ficresf);
1.215     brouard  8247:   printf("End of Computing forecasting \n");
                   8248:   fprintf(ficlog,"End of Computing forecasting\n");
                   8249: 
1.126     brouard  8250: }
                   8251: 
1.269     brouard  8252: /************** Back Forecasting ******************/
                   8253:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8254:   /* back1, year, month, day of starting backection
                   8255:      agemin, agemax range of age
                   8256:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8257:      anback2 year of end of backprojection (same day and month as back1).
                   8258:      prevacurrent and prev are prevalences.
1.267     brouard  8259:   */
                   8260:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8261:   double agec; /* generic age */
1.268     brouard  8262:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8263:   double *popeffectif,*popcount;
                   8264:   double ***p3mat;
                   8265:   /* double ***mobaverage; */
                   8266:   char fileresfb[FILENAMELENGTH];
                   8267:  
1.268     brouard  8268:   agelim=AGEINF;
1.267     brouard  8269:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8270:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8271:      We still use firstpass and lastpass as another selection.
                   8272:   */
                   8273:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8274:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8275: 
                   8276:   /*Do we need to compute prevalence again?*/
                   8277: 
                   8278:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8279:   
                   8280:   strcpy(fileresfb,"FB_");
                   8281:   strcat(fileresfb,fileresu);
                   8282:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8283:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8284:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8285:   }
                   8286:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8287:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8288:   
                   8289:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8290:   
                   8291:    
                   8292:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8293:   if (stepm<=12) stepsize=1;
                   8294:   if(estepm < stepm){
                   8295:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8296:   }
1.270     brouard  8297:   else{
                   8298:     hstepm=estepm;   
                   8299:   }
                   8300:   if(estepm >= stepm){ /* Yes every two year */
                   8301:     stepsize=2;
                   8302:   }
1.267     brouard  8303:   
                   8304:   hstepm=hstepm/stepm;
                   8305:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8306:                                fractional in yp1 */
                   8307:   anprojmean=yp;
                   8308:   yp2=modf((yp1*12),&yp);
                   8309:   mprojmean=yp;
                   8310:   yp1=modf((yp2*30.5),&yp);
                   8311:   jprojmean=yp;
                   8312:   if(jprojmean==0) jprojmean=1;
                   8313:   if(mprojmean==0) jprojmean=1;
                   8314:   
                   8315:   i1=pow(2,cptcoveff);
                   8316:   if (cptcovn < 1){i1=1;}
                   8317:   
                   8318:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8319:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8320:   
                   8321:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8322:   
                   8323:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8324:   for(k=1; k<=i1;k++){
                   8325:     if(i1 != 1 && TKresult[nres]!= k)
                   8326:       continue;
                   8327:     if(invalidvarcomb[k]){
                   8328:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8329:       continue;
                   8330:     }
1.268     brouard  8331:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8332:     for(j=1;j<=cptcoveff;j++) {
                   8333:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8334:     }
                   8335:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8336:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8337:     }
                   8338:     fprintf(ficresfb," yearbproj age");
                   8339:     for(j=1; j<=nlstate+ndeath;j++){
                   8340:       for(i=1; i<=nlstate;i++)
1.268     brouard  8341:        fprintf(ficresfb," b%d%d",i,j);
                   8342:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8343:     }
                   8344:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8345:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8346:       fprintf(ficresfb,"\n");
                   8347:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.271   ! brouard  8348:       printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.270     brouard  8349:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8350:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8351:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271   ! brouard  8352:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8353:        nhstepm = nhstepm/hstepm;
                   8354:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8355:        oldm=oldms;savm=savms;
1.268     brouard  8356:        /* computes hbxij at age agec over 1 to nhstepm */
1.271   ! brouard  8357:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8358:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8359:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8360:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8361:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8362:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8363:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8364:            break;
                   8365:          }
                   8366:        }
                   8367:        fprintf(ficresfb,"\n");
                   8368:        for(j=1;j<=cptcoveff;j++)
                   8369:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8370:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8371:        for(i=1; i<=nlstate+ndeath;i++) {
                   8372:          ppij=0.;ppi=0.;
                   8373:          for(j=1; j<=nlstate;j++) {
                   8374:            /* if (mobilav==1) */
1.269     brouard  8375:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8376:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8377:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8378:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8379:              /* else { */
                   8380:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8381:              /* } */
1.268     brouard  8382:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8383:          } /* end j */
                   8384:          if(ppi <0.99){
                   8385:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8386:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8387:          }
                   8388:          fprintf(ficresfb," %.3f", ppij);
                   8389:        }/* end j */
1.267     brouard  8390:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8391:       } /* end agec */
                   8392:     } /* end yearp */
                   8393:   } /* end k */
1.217     brouard  8394:   
1.267     brouard  8395:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8396:   
1.267     brouard  8397:   fclose(ficresfb);
                   8398:   printf("End of Computing Back forecasting \n");
                   8399:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8400:        
1.267     brouard  8401: }
1.217     brouard  8402: 
1.269     brouard  8403: /* Variance of prevalence limit: varprlim */
                   8404:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8405:     /*------- Variance of period (stable) prevalence------*/   
                   8406:  
                   8407:    char fileresvpl[FILENAMELENGTH];  
                   8408:    FILE *ficresvpl;
                   8409:    double **oldm, **savm;
                   8410:    double **varpl; /* Variances of prevalence limits by age */   
                   8411:    int i1, k, nres, j ;
                   8412:    
                   8413:     strcpy(fileresvpl,"VPL_");
                   8414:     strcat(fileresvpl,fileresu);
                   8415:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8416:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8417:       exit(0);
                   8418:     }
                   8419:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8420:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8421:     
                   8422:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8423:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8424:     
                   8425:     i1=pow(2,cptcoveff);
                   8426:     if (cptcovn < 1){i1=1;}
                   8427: 
                   8428:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8429:     for(k=1; k<=i1;k++){
                   8430:       if(i1 != 1 && TKresult[nres]!= k)
                   8431:        continue;
                   8432:       fprintf(ficresvpl,"\n#****** ");
                   8433:       printf("\n#****** ");
                   8434:       fprintf(ficlog,"\n#****** ");
                   8435:       for(j=1;j<=cptcoveff;j++) {
                   8436:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8437:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8438:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8439:       }
                   8440:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8441:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8442:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8443:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8444:       }        
                   8445:       fprintf(ficresvpl,"******\n");
                   8446:       printf("******\n");
                   8447:       fprintf(ficlog,"******\n");
                   8448:       
                   8449:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8450:       oldm=oldms;savm=savms;
                   8451:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8452:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8453:       /*}*/
                   8454:     }
                   8455:     
                   8456:     fclose(ficresvpl);
                   8457:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8458:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8459: 
                   8460:  }
                   8461: /* Variance of back prevalence: varbprlim */
                   8462:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8463:       /*------- Variance of back (stable) prevalence------*/
                   8464: 
                   8465:    char fileresvbl[FILENAMELENGTH];  
                   8466:    FILE  *ficresvbl;
                   8467: 
                   8468:    double **oldm, **savm;
                   8469:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8470:    int i1, k, nres, j ;
                   8471: 
                   8472:    strcpy(fileresvbl,"VBL_");
                   8473:    strcat(fileresvbl,fileresu);
                   8474:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8475:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8476:      exit(0);
                   8477:    }
                   8478:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8479:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8480:    
                   8481:    
                   8482:    i1=pow(2,cptcoveff);
                   8483:    if (cptcovn < 1){i1=1;}
                   8484:    
                   8485:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8486:      for(k=1; k<=i1;k++){
                   8487:        if(i1 != 1 && TKresult[nres]!= k)
                   8488:         continue;
                   8489:        fprintf(ficresvbl,"\n#****** ");
                   8490:        printf("\n#****** ");
                   8491:        fprintf(ficlog,"\n#****** ");
                   8492:        for(j=1;j<=cptcoveff;j++) {
                   8493:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8494:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8495:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8496:        }
                   8497:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8498:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8499:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8500:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8501:        }
                   8502:        fprintf(ficresvbl,"******\n");
                   8503:        printf("******\n");
                   8504:        fprintf(ficlog,"******\n");
                   8505:        
                   8506:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8507:        oldm=oldms;savm=savms;
                   8508:        
                   8509:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8510:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8511:        /*}*/
                   8512:      }
                   8513:    
                   8514:    fclose(ficresvbl);
                   8515:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8516:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8517: 
                   8518:  } /* End of varbprlim */
                   8519: 
1.126     brouard  8520: /************** Forecasting *****not tested NB*************/
1.227     brouard  8521: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8522:   
1.227     brouard  8523: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8524: /*   int *popage; */
                   8525: /*   double calagedatem, agelim, kk1, kk2; */
                   8526: /*   double *popeffectif,*popcount; */
                   8527: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8528: /*   /\* double ***mobaverage; *\/ */
                   8529: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8530: 
1.227     brouard  8531: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8532: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8533: /*   agelim=AGESUP; */
                   8534: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8535:   
1.227     brouard  8536: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8537:   
                   8538:   
1.227     brouard  8539: /*   strcpy(filerespop,"POP_");  */
                   8540: /*   strcat(filerespop,fileresu); */
                   8541: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8542: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8543: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8544: /*   } */
                   8545: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8546: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8547: 
1.227     brouard  8548: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8549: 
1.227     brouard  8550: /*   /\* if (mobilav!=0) { *\/ */
                   8551: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8552: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8553: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8554: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8555: /*   /\*   } *\/ */
                   8556: /*   /\* } *\/ */
1.126     brouard  8557: 
1.227     brouard  8558: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8559: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8560:   
1.227     brouard  8561: /*   agelim=AGESUP; */
1.126     brouard  8562:   
1.227     brouard  8563: /*   hstepm=1; */
                   8564: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8565:        
1.227     brouard  8566: /*   if (popforecast==1) { */
                   8567: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8568: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8569: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8570: /*     }  */
                   8571: /*     popage=ivector(0,AGESUP); */
                   8572: /*     popeffectif=vector(0,AGESUP); */
                   8573: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8574:     
1.227     brouard  8575: /*     i=1;    */
                   8576: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8577:     
1.227     brouard  8578: /*     imx=i; */
                   8579: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8580: /*   } */
1.218     brouard  8581:   
1.227     brouard  8582: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8583: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8584: /*       k=k+1; */
                   8585: /*       fprintf(ficrespop,"\n#******"); */
                   8586: /*       for(j=1;j<=cptcoveff;j++) { */
                   8587: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8588: /*       } */
                   8589: /*       fprintf(ficrespop,"******\n"); */
                   8590: /*       fprintf(ficrespop,"# Age"); */
                   8591: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8592: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8593:       
1.227     brouard  8594: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8595: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8596:        
1.227     brouard  8597: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8598: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8599: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8600:          
1.227     brouard  8601: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8602: /*       oldm=oldms;savm=savms; */
                   8603: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8604:          
1.227     brouard  8605: /*       for (h=0; h<=nhstepm; h++){ */
                   8606: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8607: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8608: /*         }  */
                   8609: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8610: /*           kk1=0.;kk2=0; */
                   8611: /*           for(i=1; i<=nlstate;i++) {               */
                   8612: /*             if (mobilav==1)  */
                   8613: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8614: /*             else { */
                   8615: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8616: /*             } */
                   8617: /*           } */
                   8618: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8619: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8620: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8621: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8622: /*           } */
                   8623: /*         } */
                   8624: /*         for(i=1; i<=nlstate;i++){ */
                   8625: /*           kk1=0.; */
                   8626: /*           for(j=1; j<=nlstate;j++){ */
                   8627: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8628: /*           } */
                   8629: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8630: /*         } */
1.218     brouard  8631:            
1.227     brouard  8632: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8633: /*           for(j=1; j<=nlstate;j++)  */
                   8634: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8635: /*       } */
                   8636: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8637: /*     } */
                   8638: /*       } */
1.218     brouard  8639:       
1.227     brouard  8640: /*       /\******\/ */
1.218     brouard  8641:       
1.227     brouard  8642: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8643: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8644: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8645: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8646: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8647:          
1.227     brouard  8648: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8649: /*       oldm=oldms;savm=savms; */
                   8650: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8651: /*       for (h=0; h<=nhstepm; h++){ */
                   8652: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8653: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8654: /*         }  */
                   8655: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8656: /*           kk1=0.;kk2=0; */
                   8657: /*           for(i=1; i<=nlstate;i++) {               */
                   8658: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8659: /*           } */
                   8660: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8661: /*         } */
                   8662: /*       } */
                   8663: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8664: /*     } */
                   8665: /*       } */
                   8666: /*     }  */
                   8667: /*   } */
1.218     brouard  8668:   
1.227     brouard  8669: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8670:   
1.227     brouard  8671: /*   if (popforecast==1) { */
                   8672: /*     free_ivector(popage,0,AGESUP); */
                   8673: /*     free_vector(popeffectif,0,AGESUP); */
                   8674: /*     free_vector(popcount,0,AGESUP); */
                   8675: /*   } */
                   8676: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8677: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8678: /*   fclose(ficrespop); */
                   8679: /* } /\* End of popforecast *\/ */
1.218     brouard  8680:  
1.126     brouard  8681: int fileappend(FILE *fichier, char *optionfich)
                   8682: {
                   8683:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8684:     printf("Problem with file: %s\n", optionfich);
                   8685:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8686:     return (0);
                   8687:   }
                   8688:   fflush(fichier);
                   8689:   return (1);
                   8690: }
                   8691: 
                   8692: 
                   8693: /**************** function prwizard **********************/
                   8694: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8695: {
                   8696: 
                   8697:   /* Wizard to print covariance matrix template */
                   8698: 
1.164     brouard  8699:   char ca[32], cb[32];
                   8700:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8701:   int numlinepar;
                   8702: 
                   8703:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8704:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8705:   for(i=1; i <=nlstate; i++){
                   8706:     jj=0;
                   8707:     for(j=1; j <=nlstate+ndeath; j++){
                   8708:       if(j==i) continue;
                   8709:       jj++;
                   8710:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8711:       printf("%1d%1d",i,j);
                   8712:       fprintf(ficparo,"%1d%1d",i,j);
                   8713:       for(k=1; k<=ncovmodel;k++){
                   8714:        /*        printf(" %lf",param[i][j][k]); */
                   8715:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8716:        printf(" 0.");
                   8717:        fprintf(ficparo," 0.");
                   8718:       }
                   8719:       printf("\n");
                   8720:       fprintf(ficparo,"\n");
                   8721:     }
                   8722:   }
                   8723:   printf("# Scales (for hessian or gradient estimation)\n");
                   8724:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8725:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8726:   for(i=1; i <=nlstate; i++){
                   8727:     jj=0;
                   8728:     for(j=1; j <=nlstate+ndeath; j++){
                   8729:       if(j==i) continue;
                   8730:       jj++;
                   8731:       fprintf(ficparo,"%1d%1d",i,j);
                   8732:       printf("%1d%1d",i,j);
                   8733:       fflush(stdout);
                   8734:       for(k=1; k<=ncovmodel;k++){
                   8735:        /*      printf(" %le",delti3[i][j][k]); */
                   8736:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8737:        printf(" 0.");
                   8738:        fprintf(ficparo," 0.");
                   8739:       }
                   8740:       numlinepar++;
                   8741:       printf("\n");
                   8742:       fprintf(ficparo,"\n");
                   8743:     }
                   8744:   }
                   8745:   printf("# Covariance matrix\n");
                   8746: /* # 121 Var(a12)\n\ */
                   8747: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8748: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8749: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8750: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8751: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8752: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8753: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8754:   fflush(stdout);
                   8755:   fprintf(ficparo,"# Covariance matrix\n");
                   8756:   /* # 121 Var(a12)\n\ */
                   8757:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8758:   /* #   ...\n\ */
                   8759:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8760:   
                   8761:   for(itimes=1;itimes<=2;itimes++){
                   8762:     jj=0;
                   8763:     for(i=1; i <=nlstate; i++){
                   8764:       for(j=1; j <=nlstate+ndeath; j++){
                   8765:        if(j==i) continue;
                   8766:        for(k=1; k<=ncovmodel;k++){
                   8767:          jj++;
                   8768:          ca[0]= k+'a'-1;ca[1]='\0';
                   8769:          if(itimes==1){
                   8770:            printf("#%1d%1d%d",i,j,k);
                   8771:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8772:          }else{
                   8773:            printf("%1d%1d%d",i,j,k);
                   8774:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8775:            /*  printf(" %.5le",matcov[i][j]); */
                   8776:          }
                   8777:          ll=0;
                   8778:          for(li=1;li <=nlstate; li++){
                   8779:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8780:              if(lj==li) continue;
                   8781:              for(lk=1;lk<=ncovmodel;lk++){
                   8782:                ll++;
                   8783:                if(ll<=jj){
                   8784:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8785:                  if(ll<jj){
                   8786:                    if(itimes==1){
                   8787:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8788:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8789:                    }else{
                   8790:                      printf(" 0.");
                   8791:                      fprintf(ficparo," 0.");
                   8792:                    }
                   8793:                  }else{
                   8794:                    if(itimes==1){
                   8795:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8796:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8797:                    }else{
                   8798:                      printf(" 0.");
                   8799:                      fprintf(ficparo," 0.");
                   8800:                    }
                   8801:                  }
                   8802:                }
                   8803:              } /* end lk */
                   8804:            } /* end lj */
                   8805:          } /* end li */
                   8806:          printf("\n");
                   8807:          fprintf(ficparo,"\n");
                   8808:          numlinepar++;
                   8809:        } /* end k*/
                   8810:       } /*end j */
                   8811:     } /* end i */
                   8812:   } /* end itimes */
                   8813: 
                   8814: } /* end of prwizard */
                   8815: /******************* Gompertz Likelihood ******************************/
                   8816: double gompertz(double x[])
                   8817: { 
                   8818:   double A,B,L=0.0,sump=0.,num=0.;
                   8819:   int i,n=0; /* n is the size of the sample */
                   8820: 
1.220     brouard  8821:   for (i=1;i<=imx ; i++) {
1.126     brouard  8822:     sump=sump+weight[i];
                   8823:     /*    sump=sump+1;*/
                   8824:     num=num+1;
                   8825:   }
                   8826:  
                   8827:  
                   8828:   /* for (i=0; i<=imx; i++) 
                   8829:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8830: 
                   8831:   for (i=1;i<=imx ; i++)
                   8832:     {
                   8833:       if (cens[i] == 1 && wav[i]>1)
                   8834:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8835:       
                   8836:       if (cens[i] == 0 && wav[i]>1)
                   8837:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8838:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8839:       
                   8840:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8841:       if (wav[i] > 1 ) { /* ??? */
                   8842:        L=L+A*weight[i];
                   8843:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8844:       }
                   8845:     }
                   8846: 
                   8847:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8848:  
                   8849:   return -2*L*num/sump;
                   8850: }
                   8851: 
1.136     brouard  8852: #ifdef GSL
                   8853: /******************* Gompertz_f Likelihood ******************************/
                   8854: double gompertz_f(const gsl_vector *v, void *params)
                   8855: { 
                   8856:   double A,B,LL=0.0,sump=0.,num=0.;
                   8857:   double *x= (double *) v->data;
                   8858:   int i,n=0; /* n is the size of the sample */
                   8859: 
                   8860:   for (i=0;i<=imx-1 ; i++) {
                   8861:     sump=sump+weight[i];
                   8862:     /*    sump=sump+1;*/
                   8863:     num=num+1;
                   8864:   }
                   8865:  
                   8866:  
                   8867:   /* for (i=0; i<=imx; i++) 
                   8868:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8869:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8870:   for (i=1;i<=imx ; i++)
                   8871:     {
                   8872:       if (cens[i] == 1 && wav[i]>1)
                   8873:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8874:       
                   8875:       if (cens[i] == 0 && wav[i]>1)
                   8876:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8877:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8878:       
                   8879:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8880:       if (wav[i] > 1 ) { /* ??? */
                   8881:        LL=LL+A*weight[i];
                   8882:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8883:       }
                   8884:     }
                   8885: 
                   8886:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8887:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8888:  
                   8889:   return -2*LL*num/sump;
                   8890: }
                   8891: #endif
                   8892: 
1.126     brouard  8893: /******************* Printing html file ***********/
1.201     brouard  8894: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8895:                  int lastpass, int stepm, int weightopt, char model[],\
                   8896:                  int imx,  double p[],double **matcov,double agemortsup){
                   8897:   int i,k;
                   8898: 
                   8899:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8900:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8901:   for (i=1;i<=2;i++) 
                   8902:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8903:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8904:   fprintf(fichtm,"</ul>");
                   8905: 
                   8906: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8907: 
                   8908:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8909: 
                   8910:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8911:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8912: 
                   8913:  
                   8914:   fflush(fichtm);
                   8915: }
                   8916: 
                   8917: /******************* Gnuplot file **************/
1.201     brouard  8918: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8919: 
                   8920:   char dirfileres[132],optfileres[132];
1.164     brouard  8921: 
1.126     brouard  8922:   int ng;
                   8923: 
                   8924: 
                   8925:   /*#ifdef windows */
                   8926:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8927:     /*#endif */
                   8928: 
                   8929: 
                   8930:   strcpy(dirfileres,optionfilefiname);
                   8931:   strcpy(optfileres,"vpl");
1.199     brouard  8932:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8933:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8934:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8935:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8936:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8937: 
                   8938: } 
                   8939: 
1.136     brouard  8940: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8941: {
1.126     brouard  8942: 
1.136     brouard  8943:   /*-------- data file ----------*/
                   8944:   FILE *fic;
                   8945:   char dummy[]="                         ";
1.240     brouard  8946:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8947:   int lstra;
1.136     brouard  8948:   int linei, month, year,iout;
                   8949:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8950:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8951:   char *stratrunc;
1.223     brouard  8952: 
1.240     brouard  8953:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8954:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8955: 
1.240     brouard  8956:   for(v=1; v <=ncovcol;v++){
                   8957:     DummyV[v]=0;
                   8958:     FixedV[v]=0;
                   8959:   }
                   8960:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8961:     DummyV[v]=1;
                   8962:     FixedV[v]=0;
                   8963:   }
                   8964:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8965:     DummyV[v]=0;
                   8966:     FixedV[v]=1;
                   8967:   }
                   8968:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8969:     DummyV[v]=1;
                   8970:     FixedV[v]=1;
                   8971:   }
                   8972:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8973:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8974:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8975:   }
1.126     brouard  8976: 
1.136     brouard  8977:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8978:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8979:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8980:   }
1.126     brouard  8981: 
1.136     brouard  8982:   i=1;
                   8983:   linei=0;
                   8984:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8985:     linei=linei+1;
                   8986:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8987:       if(line[j] == '\t')
                   8988:        line[j] = ' ';
                   8989:     }
                   8990:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8991:       ;
                   8992:     };
                   8993:     line[j+1]=0;  /* Trims blanks at end of line */
                   8994:     if(line[0]=='#'){
                   8995:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8996:       printf("Comment line\n%s\n",line);
                   8997:       continue;
                   8998:     }
                   8999:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9000:     strcpy(line, linetmp);
1.223     brouard  9001:     
                   9002:     /* Loops on waves */
                   9003:     for (j=maxwav;j>=1;j--){
                   9004:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9005:        cutv(stra, strb, line, ' '); 
                   9006:        if(strb[0]=='.') { /* Missing value */
                   9007:          lval=-1;
                   9008:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9009:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9010:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9011:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9012:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9013:            return 1;
                   9014:          }
                   9015:        }else{
                   9016:          errno=0;
                   9017:          /* what_kind_of_number(strb); */
                   9018:          dval=strtod(strb,&endptr); 
                   9019:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9020:          /* if(strb != endptr && *endptr == '\0') */
                   9021:          /*    dval=dlval; */
                   9022:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9023:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9024:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9025:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9026:            return 1;
                   9027:          }
                   9028:          cotqvar[j][iv][i]=dval; 
                   9029:          cotvar[j][ntv+iv][i]=dval; 
                   9030:        }
                   9031:        strcpy(line,stra);
1.223     brouard  9032:       }/* end loop ntqv */
1.225     brouard  9033:       
1.223     brouard  9034:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9035:        cutv(stra, strb, line, ' '); 
                   9036:        if(strb[0]=='.') { /* Missing value */
                   9037:          lval=-1;
                   9038:        }else{
                   9039:          errno=0;
                   9040:          lval=strtol(strb,&endptr,10); 
                   9041:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9042:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9043:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9044:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9045:            return 1;
                   9046:          }
                   9047:        }
                   9048:        if(lval <-1 || lval >1){
                   9049:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9050:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9051:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9052:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9053:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9054:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9055:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9056:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9057:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9058:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9059:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9060:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9061:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9062:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9063:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9064:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9065:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9066:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9067:          return 1;
                   9068:        }
                   9069:        cotvar[j][iv][i]=(double)(lval);
                   9070:        strcpy(line,stra);
1.223     brouard  9071:       }/* end loop ntv */
1.225     brouard  9072:       
1.223     brouard  9073:       /* Statuses  at wave */
1.137     brouard  9074:       cutv(stra, strb, line, ' '); 
1.223     brouard  9075:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9076:        lval=-1;
1.136     brouard  9077:       }else{
1.238     brouard  9078:        errno=0;
                   9079:        lval=strtol(strb,&endptr,10); 
                   9080:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9081:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9082:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9083:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9084:          return 1;
                   9085:        }
1.136     brouard  9086:       }
1.225     brouard  9087:       
1.136     brouard  9088:       s[j][i]=lval;
1.225     brouard  9089:       
1.223     brouard  9090:       /* Date of Interview */
1.136     brouard  9091:       strcpy(line,stra);
                   9092:       cutv(stra, strb,line,' ');
1.169     brouard  9093:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9094:       }
1.169     brouard  9095:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9096:        month=99;
                   9097:        year=9999;
1.136     brouard  9098:       }else{
1.225     brouard  9099:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9100:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9101:        return 1;
1.136     brouard  9102:       }
                   9103:       anint[j][i]= (double) year; 
                   9104:       mint[j][i]= (double)month; 
                   9105:       strcpy(line,stra);
1.223     brouard  9106:     } /* End loop on waves */
1.225     brouard  9107:     
1.223     brouard  9108:     /* Date of death */
1.136     brouard  9109:     cutv(stra, strb,line,' '); 
1.169     brouard  9110:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9111:     }
1.169     brouard  9112:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9113:       month=99;
                   9114:       year=9999;
                   9115:     }else{
1.141     brouard  9116:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9117:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9118:       return 1;
1.136     brouard  9119:     }
                   9120:     andc[i]=(double) year; 
                   9121:     moisdc[i]=(double) month; 
                   9122:     strcpy(line,stra);
                   9123:     
1.223     brouard  9124:     /* Date of birth */
1.136     brouard  9125:     cutv(stra, strb,line,' '); 
1.169     brouard  9126:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9127:     }
1.169     brouard  9128:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9129:       month=99;
                   9130:       year=9999;
                   9131:     }else{
1.141     brouard  9132:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9133:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9134:       return 1;
1.136     brouard  9135:     }
                   9136:     if (year==9999) {
1.141     brouard  9137:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9138:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9139:       return 1;
                   9140:       
1.136     brouard  9141:     }
                   9142:     annais[i]=(double)(year);
                   9143:     moisnais[i]=(double)(month); 
                   9144:     strcpy(line,stra);
1.225     brouard  9145:     
1.223     brouard  9146:     /* Sample weight */
1.136     brouard  9147:     cutv(stra, strb,line,' '); 
                   9148:     errno=0;
                   9149:     dval=strtod(strb,&endptr); 
                   9150:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9151:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9152:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9153:       fflush(ficlog);
                   9154:       return 1;
                   9155:     }
                   9156:     weight[i]=dval; 
                   9157:     strcpy(line,stra);
1.225     brouard  9158:     
1.223     brouard  9159:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9160:       cutv(stra, strb, line, ' '); 
                   9161:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9162:        lval=-1;
1.223     brouard  9163:       }else{
1.225     brouard  9164:        errno=0;
                   9165:        /* what_kind_of_number(strb); */
                   9166:        dval=strtod(strb,&endptr);
                   9167:        /* if(strb != endptr && *endptr == '\0') */
                   9168:        /*   dval=dlval; */
                   9169:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9170:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9171:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9172:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9173:          return 1;
                   9174:        }
                   9175:        coqvar[iv][i]=dval; 
1.226     brouard  9176:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9177:       }
                   9178:       strcpy(line,stra);
                   9179:     }/* end loop nqv */
1.136     brouard  9180:     
1.223     brouard  9181:     /* Covariate values */
1.136     brouard  9182:     for (j=ncovcol;j>=1;j--){
                   9183:       cutv(stra, strb,line,' '); 
1.223     brouard  9184:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9185:        lval=-1;
1.136     brouard  9186:       }else{
1.225     brouard  9187:        errno=0;
                   9188:        lval=strtol(strb,&endptr,10); 
                   9189:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9190:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9191:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9192:          return 1;
                   9193:        }
1.136     brouard  9194:       }
                   9195:       if(lval <-1 || lval >1){
1.225     brouard  9196:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9197:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9198:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9199:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9200:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9201:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9202:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9203:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9204:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9205:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9206:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9207:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9208:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9209:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9210:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9211:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9212:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9213:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9214:        return 1;
1.136     brouard  9215:       }
                   9216:       covar[j][i]=(double)(lval);
                   9217:       strcpy(line,stra);
                   9218:     }  
                   9219:     lstra=strlen(stra);
1.225     brouard  9220:     
1.136     brouard  9221:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9222:       stratrunc = &(stra[lstra-9]);
                   9223:       num[i]=atol(stratrunc);
                   9224:     }
                   9225:     else
                   9226:       num[i]=atol(stra);
                   9227:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9228:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9229:     
                   9230:     i=i+1;
                   9231:   } /* End loop reading  data */
1.225     brouard  9232:   
1.136     brouard  9233:   *imax=i-1; /* Number of individuals */
                   9234:   fclose(fic);
1.225     brouard  9235:   
1.136     brouard  9236:   return (0);
1.164     brouard  9237:   /* endread: */
1.225     brouard  9238:   printf("Exiting readdata: ");
                   9239:   fclose(fic);
                   9240:   return (1);
1.223     brouard  9241: }
1.126     brouard  9242: 
1.234     brouard  9243: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9244:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9245:   while (*p2 == ' ')
1.234     brouard  9246:     p2++; 
                   9247:   /* while ((*p1++ = *p2++) !=0) */
                   9248:   /*   ; */
                   9249:   /* do */
                   9250:   /*   while (*p2 == ' ') */
                   9251:   /*     p2++; */
                   9252:   /* while (*p1++ == *p2++); */
                   9253:   *stri=p2; 
1.145     brouard  9254: }
                   9255: 
1.235     brouard  9256: int decoderesult ( char resultline[], int nres)
1.230     brouard  9257: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9258: {
1.235     brouard  9259:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9260:   char resultsav[MAXLINE];
1.234     brouard  9261:   int resultmodel[MAXLINE];
                   9262:   int modelresult[MAXLINE];
1.230     brouard  9263:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9264: 
1.234     brouard  9265:   removefirstspace(&resultline);
1.233     brouard  9266:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9267: 
                   9268:   if (strstr(resultline,"v") !=0){
                   9269:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9270:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9271:     return 1;
                   9272:   }
                   9273:   trimbb(resultsav, resultline);
                   9274:   if (strlen(resultsav) >1){
                   9275:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9276:   }
1.253     brouard  9277:   if(j == 0){ /* Resultline but no = */
                   9278:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9279:     return (0);
                   9280:   }
                   9281:     
1.234     brouard  9282:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9283:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9284:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9285:   }
                   9286:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9287:     if(nbocc(resultsav,'=') >1){
                   9288:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9289:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9290:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9291:     }else
                   9292:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9293:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9294:     
1.230     brouard  9295:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9296:     Tvarsel[k]=atoi(strc);
                   9297:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9298:     /* cptcovsel++;     */
                   9299:     if (nbocc(stra,'=') >0)
                   9300:       strcpy(resultsav,stra); /* and analyzes it */
                   9301:   }
1.235     brouard  9302:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9303:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9304:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9305:       match=0;
1.236     brouard  9306:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9307:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9308:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9309:          match=1;
                   9310:          break;
                   9311:        }
                   9312:       }
                   9313:       if(match == 0){
                   9314:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9315:       }
                   9316:     }
                   9317:   }
1.235     brouard  9318:   /* Checking for missing or useless values in comparison of current model needs */
                   9319:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9320:     match=0;
1.235     brouard  9321:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9322:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9323:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9324:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9325:          ++match;
                   9326:        }
                   9327:       }
                   9328:     }
                   9329:     if(match == 0){
                   9330:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9331:     }else if(match > 1){
                   9332:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9333:     }
                   9334:   }
1.235     brouard  9335:       
1.234     brouard  9336:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9337:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9338:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9339:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9340:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9341:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9342:   /*    1 0 0 0 */
                   9343:   /*    2 1 0 0 */
                   9344:   /*    3 0 1 0 */ 
                   9345:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9346:   /*    5 0 0 1 */
                   9347:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9348:   /*    7 0 1 1 */
                   9349:   /*    8 1 1 1 */
1.237     brouard  9350:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9351:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9352:   /* V5*age V5 known which value for nres?  */
                   9353:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9354:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9355:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9356:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9357:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9358:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9359:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9360:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9361:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9362:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9363:       k4++;;
                   9364:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9365:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9366:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9367:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9368:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9369:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9370:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9371:       k4q++;;
                   9372:     }
                   9373:   }
1.234     brouard  9374:   
1.235     brouard  9375:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9376:   return (0);
                   9377: }
1.235     brouard  9378: 
1.230     brouard  9379: int decodemodel( char model[], int lastobs)
                   9380:  /**< This routine decodes the model and returns:
1.224     brouard  9381:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9382:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9383:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9384:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9385:        * - cptcovage number of covariates with age*products =2
                   9386:        * - cptcovs number of simple covariates
                   9387:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9388:        *     which is a new column after the 9 (ncovcol) variables. 
                   9389:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9390:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9391:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9392:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9393:        */
1.136     brouard  9394: {
1.238     brouard  9395:   int i, j, k, ks, v;
1.227     brouard  9396:   int  j1, k1, k2, k3, k4;
1.136     brouard  9397:   char modelsav[80];
1.145     brouard  9398:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9399:   char *strpt;
1.136     brouard  9400: 
1.145     brouard  9401:   /*removespace(model);*/
1.136     brouard  9402:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9403:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9404:     if (strstr(model,"AGE") !=0){
1.192     brouard  9405:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9406:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9407:       return 1;
                   9408:     }
1.141     brouard  9409:     if (strstr(model,"v") !=0){
                   9410:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9411:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9412:       return 1;
                   9413:     }
1.187     brouard  9414:     strcpy(modelsav,model); 
                   9415:     if ((strpt=strstr(model,"age*age")) !=0){
                   9416:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9417:       if(strpt != model){
1.234     brouard  9418:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9419:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9420:  corresponding column of parameters.\n",model);
1.234     brouard  9421:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9422:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9423:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9424:        return 1;
1.225     brouard  9425:       }
1.187     brouard  9426:       nagesqr=1;
                   9427:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9428:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9429:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9430:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9431:       else 
1.234     brouard  9432:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9433:     }else
                   9434:       nagesqr=0;
                   9435:     if (strlen(modelsav) >1){
                   9436:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9437:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9438:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9439:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9440:                     * cst, age and age*age 
                   9441:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9442:       /* including age products which are counted in cptcovage.
                   9443:        * but the covariates which are products must be treated 
                   9444:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9445:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9446:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9447:       
                   9448:       
1.187     brouard  9449:       /*   Design
                   9450:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9451:        *  <          ncovcol=8                >
                   9452:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9453:        *   k=  1    2      3       4     5       6      7        8
                   9454:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9455:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9456:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9457:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9458:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9459:        *  Tage[++cptcovage]=k
                   9460:        *       if products, new covar are created after ncovcol with k1
                   9461:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9462:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9463:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9464:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9465:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9466:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9467:        *  <          ncovcol=8                >
                   9468:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9469:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9470:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9471:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9472:        * p Tprod[1]@2={                         6, 5}
                   9473:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9474:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9475:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9476:        *How to reorganize?
                   9477:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9478:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9479:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9480:        * Struct []
                   9481:        */
1.225     brouard  9482:       
1.187     brouard  9483:       /* This loop fills the array Tvar from the string 'model'.*/
                   9484:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9485:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9486:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9487:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9488:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9489:       /*       k=1 Tvar[1]=2 (from V2) */
                   9490:       /*       k=5 Tvar[5] */
                   9491:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9492:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9493:       /*       } */
1.198     brouard  9494:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9495:       /*
                   9496:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9497:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9498:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9499:       }
1.187     brouard  9500:       cptcovage=0;
                   9501:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9502:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9503:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9504:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9505:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9506:        /*scanf("%d",i);*/
                   9507:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9508:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9509:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9510:            /* covar is not filled and then is empty */
                   9511:            cptcovprod--;
                   9512:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9513:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9514:            Typevar[k]=1;  /* 1 for age product */
                   9515:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9516:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9517:            /*printf("stre=%s ", stre);*/
                   9518:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9519:            cptcovprod--;
                   9520:            cutl(stre,strb,strc,'V');
                   9521:            Tvar[k]=atoi(stre);
                   9522:            Typevar[k]=1;  /* 1 for age product */
                   9523:            cptcovage++;
                   9524:            Tage[cptcovage]=k;
                   9525:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9526:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9527:            cptcovn++;
                   9528:            cptcovprodnoage++;k1++;
                   9529:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9530:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9531:                                                because this model-covariate is a construction we invent a new column
                   9532:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9533:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9534:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9535:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9536:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9537:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9538:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9539:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9540:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9541:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9542:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9543:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9544:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9545:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9546:            for (i=1; i<=lastobs;i++){
                   9547:              /* Computes the new covariate which is a product of
                   9548:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9549:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9550:            }
                   9551:          } /* End age is not in the model */
                   9552:        } /* End if model includes a product */
                   9553:        else { /* no more sum */
                   9554:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9555:          /*  scanf("%d",i);*/
                   9556:          cutl(strd,strc,strb,'V');
                   9557:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9558:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9559:          Tvar[k]=atoi(strd);
                   9560:          Typevar[k]=0;  /* 0 for simple covariates */
                   9561:        }
                   9562:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9563:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9564:                                  scanf("%d",i);*/
1.187     brouard  9565:       } /* end of loop + on total covariates */
                   9566:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9567:   } /* end if strlen(model == 0) */
1.136     brouard  9568:   
                   9569:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9570:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9571:   
1.136     brouard  9572:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9573:      printf("cptcovprod=%d ", cptcovprod);
                   9574:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9575:      scanf("%d ",i);*/
                   9576: 
                   9577: 
1.230     brouard  9578: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9579:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9580: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9581:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9582:    k =           1    2   3     4       5       6      7      8        9
                   9583:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9584:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9585:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9586:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9587:          Tmodelind[combination of covar]=k;
1.225     brouard  9588: */  
                   9589: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9590:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9591:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9592:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9593:   printf("Model=%s\n\
                   9594: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9595: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9596: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9597:   fprintf(ficlog,"Model=%s\n\
                   9598: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9599: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9600: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9601:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9602:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9603:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9604:       Fixed[k]= 0;
                   9605:       Dummy[k]= 0;
1.225     brouard  9606:       ncoveff++;
1.232     brouard  9607:       ncovf++;
1.234     brouard  9608:       nsd++;
                   9609:       modell[k].maintype= FTYPE;
                   9610:       TvarsD[nsd]=Tvar[k];
                   9611:       TvarsDind[nsd]=k;
                   9612:       TvarF[ncovf]=Tvar[k];
                   9613:       TvarFind[ncovf]=k;
                   9614:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9615:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9616:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9617:       Fixed[k]= 0;
                   9618:       Dummy[k]= 0;
                   9619:       ncoveff++;
                   9620:       ncovf++;
                   9621:       modell[k].maintype= FTYPE;
                   9622:       TvarF[ncovf]=Tvar[k];
                   9623:       TvarFind[ncovf]=k;
1.230     brouard  9624:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9625:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9626:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9627:       Fixed[k]= 0;
                   9628:       Dummy[k]= 1;
1.230     brouard  9629:       nqfveff++;
1.234     brouard  9630:       modell[k].maintype= FTYPE;
                   9631:       modell[k].subtype= FQ;
                   9632:       nsq++;
                   9633:       TvarsQ[nsq]=Tvar[k];
                   9634:       TvarsQind[nsq]=k;
1.232     brouard  9635:       ncovf++;
1.234     brouard  9636:       TvarF[ncovf]=Tvar[k];
                   9637:       TvarFind[ncovf]=k;
1.231     brouard  9638:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9639:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9640:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9641:       Fixed[k]= 1;
                   9642:       Dummy[k]= 0;
1.225     brouard  9643:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9644:       modell[k].maintype= VTYPE;
                   9645:       modell[k].subtype= VD;
                   9646:       nsd++;
                   9647:       TvarsD[nsd]=Tvar[k];
                   9648:       TvarsDind[nsd]=k;
                   9649:       ncovv++; /* Only simple time varying variables */
                   9650:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9651:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9652:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9653:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9654:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9655:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9656:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9657:       Fixed[k]= 1;
                   9658:       Dummy[k]= 1;
                   9659:       nqtveff++;
                   9660:       modell[k].maintype= VTYPE;
                   9661:       modell[k].subtype= VQ;
                   9662:       ncovv++; /* Only simple time varying variables */
                   9663:       nsq++;
                   9664:       TvarsQ[nsq]=Tvar[k];
                   9665:       TvarsQind[nsq]=k;
                   9666:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9667:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9668:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9669:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9670:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9671:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9672:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9673:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9674:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9675:       ncova++;
                   9676:       TvarA[ncova]=Tvar[k];
                   9677:       TvarAind[ncova]=k;
1.231     brouard  9678:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9679:        Fixed[k]= 2;
                   9680:        Dummy[k]= 2;
                   9681:        modell[k].maintype= ATYPE;
                   9682:        modell[k].subtype= APFD;
                   9683:        /* ncoveff++; */
1.227     brouard  9684:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9685:        Fixed[k]= 2;
                   9686:        Dummy[k]= 3;
                   9687:        modell[k].maintype= ATYPE;
                   9688:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9689:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9690:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9691:        Fixed[k]= 3;
                   9692:        Dummy[k]= 2;
                   9693:        modell[k].maintype= ATYPE;
                   9694:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9695:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9696:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9697:        Fixed[k]= 3;
                   9698:        Dummy[k]= 3;
                   9699:        modell[k].maintype= ATYPE;
                   9700:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9701:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9702:       }
                   9703:     }else if (Typevar[k] == 2) {  /* product without age */
                   9704:       k1=Tposprod[k];
                   9705:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9706:        if(Tvard[k1][2] <=ncovcol){
                   9707:          Fixed[k]= 1;
                   9708:          Dummy[k]= 0;
                   9709:          modell[k].maintype= FTYPE;
                   9710:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9711:          ncovf++; /* Fixed variables without age */
                   9712:          TvarF[ncovf]=Tvar[k];
                   9713:          TvarFind[ncovf]=k;
                   9714:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9715:          Fixed[k]= 0;  /* or 2 ?*/
                   9716:          Dummy[k]= 1;
                   9717:          modell[k].maintype= FTYPE;
                   9718:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9719:          ncovf++; /* Varying variables without age */
                   9720:          TvarF[ncovf]=Tvar[k];
                   9721:          TvarFind[ncovf]=k;
                   9722:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9723:          Fixed[k]= 1;
                   9724:          Dummy[k]= 0;
                   9725:          modell[k].maintype= VTYPE;
                   9726:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9727:          ncovv++; /* Varying variables without age */
                   9728:          TvarV[ncovv]=Tvar[k];
                   9729:          TvarVind[ncovv]=k;
                   9730:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9731:          Fixed[k]= 1;
                   9732:          Dummy[k]= 1;
                   9733:          modell[k].maintype= VTYPE;
                   9734:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9735:          ncovv++; /* Varying variables without age */
                   9736:          TvarV[ncovv]=Tvar[k];
                   9737:          TvarVind[ncovv]=k;
                   9738:        }
1.227     brouard  9739:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9740:        if(Tvard[k1][2] <=ncovcol){
                   9741:          Fixed[k]= 0;  /* or 2 ?*/
                   9742:          Dummy[k]= 1;
                   9743:          modell[k].maintype= FTYPE;
                   9744:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9745:          ncovf++; /* Fixed variables without age */
                   9746:          TvarF[ncovf]=Tvar[k];
                   9747:          TvarFind[ncovf]=k;
                   9748:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9749:          Fixed[k]= 1;
                   9750:          Dummy[k]= 1;
                   9751:          modell[k].maintype= VTYPE;
                   9752:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9753:          ncovv++; /* Varying variables without age */
                   9754:          TvarV[ncovv]=Tvar[k];
                   9755:          TvarVind[ncovv]=k;
                   9756:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9757:          Fixed[k]= 1;
                   9758:          Dummy[k]= 1;
                   9759:          modell[k].maintype= VTYPE;
                   9760:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9761:          ncovv++; /* Varying variables without age */
                   9762:          TvarV[ncovv]=Tvar[k];
                   9763:          TvarVind[ncovv]=k;
                   9764:          ncovv++; /* Varying variables without age */
                   9765:          TvarV[ncovv]=Tvar[k];
                   9766:          TvarVind[ncovv]=k;
                   9767:        }
1.227     brouard  9768:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9769:        if(Tvard[k1][2] <=ncovcol){
                   9770:          Fixed[k]= 1;
                   9771:          Dummy[k]= 1;
                   9772:          modell[k].maintype= VTYPE;
                   9773:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9774:          ncovv++; /* Varying variables without age */
                   9775:          TvarV[ncovv]=Tvar[k];
                   9776:          TvarVind[ncovv]=k;
                   9777:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9778:          Fixed[k]= 1;
                   9779:          Dummy[k]= 1;
                   9780:          modell[k].maintype= VTYPE;
                   9781:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9782:          ncovv++; /* Varying variables without age */
                   9783:          TvarV[ncovv]=Tvar[k];
                   9784:          TvarVind[ncovv]=k;
                   9785:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9786:          Fixed[k]= 1;
                   9787:          Dummy[k]= 0;
                   9788:          modell[k].maintype= VTYPE;
                   9789:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9790:          ncovv++; /* Varying variables without age */
                   9791:          TvarV[ncovv]=Tvar[k];
                   9792:          TvarVind[ncovv]=k;
                   9793:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9794:          Fixed[k]= 1;
                   9795:          Dummy[k]= 1;
                   9796:          modell[k].maintype= VTYPE;
                   9797:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9798:          ncovv++; /* Varying variables without age */
                   9799:          TvarV[ncovv]=Tvar[k];
                   9800:          TvarVind[ncovv]=k;
                   9801:        }
1.227     brouard  9802:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9803:        if(Tvard[k1][2] <=ncovcol){
                   9804:          Fixed[k]= 1;
                   9805:          Dummy[k]= 1;
                   9806:          modell[k].maintype= VTYPE;
                   9807:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9808:          ncovv++; /* Varying variables without age */
                   9809:          TvarV[ncovv]=Tvar[k];
                   9810:          TvarVind[ncovv]=k;
                   9811:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9812:          Fixed[k]= 1;
                   9813:          Dummy[k]= 1;
                   9814:          modell[k].maintype= VTYPE;
                   9815:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9816:          ncovv++; /* Varying variables without age */
                   9817:          TvarV[ncovv]=Tvar[k];
                   9818:          TvarVind[ncovv]=k;
                   9819:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9820:          Fixed[k]= 1;
                   9821:          Dummy[k]= 1;
                   9822:          modell[k].maintype= VTYPE;
                   9823:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9824:          ncovv++; /* Varying variables without age */
                   9825:          TvarV[ncovv]=Tvar[k];
                   9826:          TvarVind[ncovv]=k;
                   9827:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9828:          Fixed[k]= 1;
                   9829:          Dummy[k]= 1;
                   9830:          modell[k].maintype= VTYPE;
                   9831:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9832:          ncovv++; /* Varying variables without age */
                   9833:          TvarV[ncovv]=Tvar[k];
                   9834:          TvarVind[ncovv]=k;
                   9835:        }
1.227     brouard  9836:       }else{
1.240     brouard  9837:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9838:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9839:       } /*end k1*/
1.225     brouard  9840:     }else{
1.226     brouard  9841:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9842:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9843:     }
1.227     brouard  9844:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9845:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9846:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9847:   }
                   9848:   /* Searching for doublons in the model */
                   9849:   for(k1=1; k1<= cptcovt;k1++){
                   9850:     for(k2=1; k2 <k1;k2++){
                   9851:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9852:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9853:          if(Tvar[k1]==Tvar[k2]){
                   9854:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9855:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9856:            return(1);
                   9857:          }
                   9858:        }else if (Typevar[k1] ==2){
                   9859:          k3=Tposprod[k1];
                   9860:          k4=Tposprod[k2];
                   9861:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9862:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9863:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9864:            return(1);
                   9865:          }
                   9866:        }
1.227     brouard  9867:       }
                   9868:     }
1.225     brouard  9869:   }
                   9870:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9871:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9872:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9873:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9874:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9875:   /*endread:*/
1.225     brouard  9876:   printf("Exiting decodemodel: ");
                   9877:   return (1);
1.136     brouard  9878: }
                   9879: 
1.169     brouard  9880: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9881: {/* Check ages at death */
1.136     brouard  9882:   int i, m;
1.218     brouard  9883:   int firstone=0;
                   9884:   
1.136     brouard  9885:   for (i=1; i<=imx; i++) {
                   9886:     for(m=2; (m<= maxwav); m++) {
                   9887:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9888:        anint[m][i]=9999;
1.216     brouard  9889:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9890:          s[m][i]=-1;
1.136     brouard  9891:       }
                   9892:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9893:        *nberr = *nberr + 1;
1.218     brouard  9894:        if(firstone == 0){
                   9895:          firstone=1;
1.260     brouard  9896:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9897:        }
1.262     brouard  9898:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9899:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9900:       }
                   9901:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9902:        (*nberr)++;
1.259     brouard  9903:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9904:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9905:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9906:       }
                   9907:     }
                   9908:   }
                   9909: 
                   9910:   for (i=1; i<=imx; i++)  {
                   9911:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9912:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9913:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9914:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9915:          if(agedc[i]>0){
                   9916:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9917:              agev[m][i]=agedc[i];
1.214     brouard  9918:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9919:            }else {
1.136     brouard  9920:              if ((int)andc[i]!=9999){
                   9921:                nbwarn++;
                   9922:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9923:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9924:                agev[m][i]=-1;
                   9925:              }
                   9926:            }
1.169     brouard  9927:          } /* agedc > 0 */
1.214     brouard  9928:        } /* end if */
1.136     brouard  9929:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9930:                                 years but with the precision of a month */
                   9931:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9932:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9933:            agev[m][i]=1;
                   9934:          else if(agev[m][i] < *agemin){ 
                   9935:            *agemin=agev[m][i];
                   9936:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9937:          }
                   9938:          else if(agev[m][i] >*agemax){
                   9939:            *agemax=agev[m][i];
1.156     brouard  9940:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9941:          }
                   9942:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9943:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9944:        } /* en if 9*/
1.136     brouard  9945:        else { /* =9 */
1.214     brouard  9946:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9947:          agev[m][i]=1;
                   9948:          s[m][i]=-1;
                   9949:        }
                   9950:       }
1.214     brouard  9951:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9952:        agev[m][i]=1;
1.214     brouard  9953:       else{
                   9954:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9955:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9956:        agev[m][i]=0;
                   9957:       }
                   9958:     } /* End for lastpass */
                   9959:   }
1.136     brouard  9960:     
                   9961:   for (i=1; i<=imx; i++)  {
                   9962:     for(m=firstpass; (m<=lastpass); m++){
                   9963:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9964:        (*nberr)++;
1.136     brouard  9965:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9966:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9967:        return 1;
                   9968:       }
                   9969:     }
                   9970:   }
                   9971: 
                   9972:   /*for (i=1; i<=imx; i++){
                   9973:   for (m=firstpass; (m<lastpass); m++){
                   9974:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9975: }
                   9976: 
                   9977: }*/
                   9978: 
                   9979: 
1.139     brouard  9980:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9981:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9982: 
                   9983:   return (0);
1.164     brouard  9984:  /* endread:*/
1.136     brouard  9985:     printf("Exiting calandcheckages: ");
                   9986:     return (1);
                   9987: }
                   9988: 
1.172     brouard  9989: #if defined(_MSC_VER)
                   9990: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9991: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9992: //#include "stdafx.h"
                   9993: //#include <stdio.h>
                   9994: //#include <tchar.h>
                   9995: //#include <windows.h>
                   9996: //#include <iostream>
                   9997: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9998: 
                   9999: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10000: 
                   10001: BOOL IsWow64()
                   10002: {
                   10003:        BOOL bIsWow64 = FALSE;
                   10004: 
                   10005:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10006:        //  (HANDLE, PBOOL);
                   10007: 
                   10008:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10009: 
                   10010:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10011:        const char funcName[] = "IsWow64Process";
                   10012:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10013:                GetProcAddress(module, funcName);
                   10014: 
                   10015:        if (NULL != fnIsWow64Process)
                   10016:        {
                   10017:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10018:                        &bIsWow64))
                   10019:                        //throw std::exception("Unknown error");
                   10020:                        printf("Unknown error\n");
                   10021:        }
                   10022:        return bIsWow64 != FALSE;
                   10023: }
                   10024: #endif
1.177     brouard  10025: 
1.191     brouard  10026: void syscompilerinfo(int logged)
1.167     brouard  10027:  {
                   10028:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10029:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10030:    /* /GS /W3 /Gy
                   10031:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10032:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10033:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10034:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10035:    */ 
                   10036:    /* 64 bits */
1.185     brouard  10037:    /*
                   10038:      /GS /W3 /Gy
                   10039:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10040:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10041:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10042:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10043:    /* Optimization are useless and O3 is slower than O2 */
                   10044:    /*
                   10045:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10046:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10047:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10048:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10049:    */
1.186     brouard  10050:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10051:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10052:       /PDB:"visual studio
                   10053:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10054:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10055:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10056:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10057:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10058:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10059:       uiAccess='false'"
                   10060:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10061:       /NOLOGO /TLBID:1
                   10062:    */
1.177     brouard  10063: #if defined __INTEL_COMPILER
1.178     brouard  10064: #if defined(__GNUC__)
                   10065:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10066: #endif
1.177     brouard  10067: #elif defined(__GNUC__) 
1.179     brouard  10068: #ifndef  __APPLE__
1.174     brouard  10069: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10070: #endif
1.177     brouard  10071:    struct utsname sysInfo;
1.178     brouard  10072:    int cross = CROSS;
                   10073:    if (cross){
                   10074:           printf("Cross-");
1.191     brouard  10075:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10076:    }
1.174     brouard  10077: #endif
                   10078: 
1.171     brouard  10079: #include <stdint.h>
1.178     brouard  10080: 
1.191     brouard  10081:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10082: #if defined(__clang__)
1.191     brouard  10083:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10084: #endif
                   10085: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10086:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10087: #endif
                   10088: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10089:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10090: #endif
                   10091: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10092:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10093: #endif
                   10094: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10095:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10096: #endif
                   10097: #if defined(_MSC_VER)
1.191     brouard  10098:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10099: #endif
                   10100: #if defined(__PGI)
1.191     brouard  10101:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10102: #endif
                   10103: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10104:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10105: #endif
1.191     brouard  10106:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10107:    
1.167     brouard  10108: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10109: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10110:     // Windows (x64 and x86)
1.191     brouard  10111:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10112: #elif __unix__ // all unices, not all compilers
                   10113:     // Unix
1.191     brouard  10114:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10115: #elif __linux__
                   10116:     // linux
1.191     brouard  10117:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10118: #elif __APPLE__
1.174     brouard  10119:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10120:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10121: #endif
                   10122: 
                   10123: /*  __MINGW32__          */
                   10124: /*  __CYGWIN__  */
                   10125: /* __MINGW64__  */
                   10126: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10127: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10128: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10129: /* _WIN64  // Defined for applications for Win64. */
                   10130: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10131: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10132: 
1.167     brouard  10133: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10134:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10135: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10136:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10137: #else
1.191     brouard  10138:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10139: #endif
                   10140: 
1.169     brouard  10141: #if defined(__GNUC__)
                   10142: # if defined(__GNUC_PATCHLEVEL__)
                   10143: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10144:                             + __GNUC_MINOR__ * 100 \
                   10145:                             + __GNUC_PATCHLEVEL__)
                   10146: # else
                   10147: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10148:                             + __GNUC_MINOR__ * 100)
                   10149: # endif
1.174     brouard  10150:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10151:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10152: 
                   10153:    if (uname(&sysInfo) != -1) {
                   10154:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10155:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10156:    }
                   10157:    else
                   10158:       perror("uname() error");
1.179     brouard  10159:    //#ifndef __INTEL_COMPILER 
                   10160: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10161:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10162:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10163: #endif
1.169     brouard  10164: #endif
1.172     brouard  10165: 
                   10166:    //   void main()
                   10167:    //   {
1.169     brouard  10168: #if defined(_MSC_VER)
1.174     brouard  10169:    if (IsWow64()){
1.191     brouard  10170:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10171:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10172:    }
                   10173:    else{
1.191     brouard  10174:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10175:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10176:    }
1.172     brouard  10177:    //     printf("\nPress Enter to continue...");
                   10178:    //     getchar();
                   10179:    //   }
                   10180: 
1.169     brouard  10181: #endif
                   10182:    
1.167     brouard  10183: 
1.219     brouard  10184: }
1.136     brouard  10185: 
1.219     brouard  10186: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10187:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10188:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10189:   /* double ftolpl = 1.e-10; */
1.180     brouard  10190:   double age, agebase, agelim;
1.203     brouard  10191:   double tot;
1.180     brouard  10192: 
1.202     brouard  10193:   strcpy(filerespl,"PL_");
                   10194:   strcat(filerespl,fileresu);
                   10195:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10196:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10197:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10198:   }
1.227     brouard  10199:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10200:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10201:   pstamp(ficrespl);
1.203     brouard  10202:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10203:   fprintf(ficrespl,"#Age ");
                   10204:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10205:   fprintf(ficrespl,"\n");
1.180     brouard  10206:   
1.219     brouard  10207:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10208: 
1.219     brouard  10209:   agebase=ageminpar;
                   10210:   agelim=agemaxpar;
1.180     brouard  10211: 
1.227     brouard  10212:   /* i1=pow(2,ncoveff); */
1.234     brouard  10213:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10214:   if (cptcovn < 1){i1=1;}
1.180     brouard  10215: 
1.238     brouard  10216:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10217:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10218:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10219:        continue;
1.235     brouard  10220: 
1.238     brouard  10221:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10222:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10223:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10224:       /* k=k+1; */
                   10225:       /* to clean */
                   10226:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10227:       fprintf(ficrespl,"#******");
                   10228:       printf("#******");
                   10229:       fprintf(ficlog,"#******");
                   10230:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10231:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10232:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10233:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10234:       }
                   10235:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10236:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10237:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10238:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10239:       }
                   10240:       fprintf(ficrespl,"******\n");
                   10241:       printf("******\n");
                   10242:       fprintf(ficlog,"******\n");
                   10243:       if(invalidvarcomb[k]){
                   10244:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10245:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10246:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10247:        continue;
                   10248:       }
1.219     brouard  10249: 
1.238     brouard  10250:       fprintf(ficrespl,"#Age ");
                   10251:       for(j=1;j<=cptcoveff;j++) {
                   10252:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10253:       }
                   10254:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10255:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10256:     
1.238     brouard  10257:       for (age=agebase; age<=agelim; age++){
                   10258:        /* for (age=agebase; age<=agebase; age++){ */
                   10259:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10260:        fprintf(ficrespl,"%.0f ",age );
                   10261:        for(j=1;j<=cptcoveff;j++)
                   10262:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10263:        tot=0.;
                   10264:        for(i=1; i<=nlstate;i++){
                   10265:          tot +=  prlim[i][i];
                   10266:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10267:        }
                   10268:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10269:       } /* Age */
                   10270:       /* was end of cptcod */
                   10271:     } /* cptcov */
                   10272:   } /* nres */
1.219     brouard  10273:   return 0;
1.180     brouard  10274: }
                   10275: 
1.218     brouard  10276: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10277:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10278:        
                   10279:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10280:    * at any age between ageminpar and agemaxpar
                   10281:         */
1.235     brouard  10282:   int i, j, k, i1, nres=0 ;
1.217     brouard  10283:   /* double ftolpl = 1.e-10; */
                   10284:   double age, agebase, agelim;
                   10285:   double tot;
1.218     brouard  10286:   /* double ***mobaverage; */
                   10287:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10288: 
                   10289:   strcpy(fileresplb,"PLB_");
                   10290:   strcat(fileresplb,fileresu);
                   10291:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10292:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10293:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10294:   }
                   10295:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10296:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10297:   pstamp(ficresplb);
                   10298:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10299:   fprintf(ficresplb,"#Age ");
                   10300:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10301:   fprintf(ficresplb,"\n");
                   10302:   
1.218     brouard  10303:   
                   10304:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10305:   
                   10306:   agebase=ageminpar;
                   10307:   agelim=agemaxpar;
                   10308:   
                   10309:   
1.227     brouard  10310:   i1=pow(2,cptcoveff);
1.218     brouard  10311:   if (cptcovn < 1){i1=1;}
1.227     brouard  10312:   
1.238     brouard  10313:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10314:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10315:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10316:        continue;
                   10317:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10318:       fprintf(ficresplb,"#******");
                   10319:       printf("#******");
                   10320:       fprintf(ficlog,"#******");
                   10321:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10322:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10323:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10324:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10325:       }
                   10326:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10327:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10328:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10329:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10330:       }
                   10331:       fprintf(ficresplb,"******\n");
                   10332:       printf("******\n");
                   10333:       fprintf(ficlog,"******\n");
                   10334:       if(invalidvarcomb[k]){
                   10335:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10336:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10337:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10338:        continue;
                   10339:       }
1.218     brouard  10340:     
1.238     brouard  10341:       fprintf(ficresplb,"#Age ");
                   10342:       for(j=1;j<=cptcoveff;j++) {
                   10343:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10344:       }
                   10345:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10346:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10347:     
                   10348:     
1.238     brouard  10349:       for (age=agebase; age<=agelim; age++){
                   10350:        /* for (age=agebase; age<=agebase; age++){ */
                   10351:        if(mobilavproj > 0){
                   10352:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10353:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10354:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10355:        }else if (mobilavproj == 0){
                   10356:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10357:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10358:          exit(1);
                   10359:        }else{
                   10360:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10361:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10362:          /* printf("TOTOT\n"); */
                   10363:           /* exit(1); */
1.238     brouard  10364:        }
                   10365:        fprintf(ficresplb,"%.0f ",age );
                   10366:        for(j=1;j<=cptcoveff;j++)
                   10367:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10368:        tot=0.;
                   10369:        for(i=1; i<=nlstate;i++){
                   10370:          tot +=  bprlim[i][i];
                   10371:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10372:        }
                   10373:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10374:       } /* Age */
                   10375:       /* was end of cptcod */
1.255     brouard  10376:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10377:     } /* end of any combination */
                   10378:   } /* end of nres */  
1.218     brouard  10379:   /* hBijx(p, bage, fage); */
                   10380:   /* fclose(ficrespijb); */
                   10381:   
                   10382:   return 0;
1.217     brouard  10383: }
1.218     brouard  10384:  
1.180     brouard  10385: int hPijx(double *p, int bage, int fage){
                   10386:     /*------------- h Pij x at various ages ------------*/
                   10387: 
                   10388:   int stepsize;
                   10389:   int agelim;
                   10390:   int hstepm;
                   10391:   int nhstepm;
1.235     brouard  10392:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10393: 
                   10394:   double agedeb;
                   10395:   double ***p3mat;
                   10396: 
1.201     brouard  10397:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10398:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10399:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10400:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10401:     }
                   10402:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10403:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10404:   
                   10405:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10406:     /*if (stepm<=24) stepsize=2;*/
                   10407: 
                   10408:     agelim=AGESUP;
                   10409:     hstepm=stepsize*YEARM; /* Every year of age */
                   10410:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10411:                
1.180     brouard  10412:     /* hstepm=1;   aff par mois*/
                   10413:     pstamp(ficrespij);
                   10414:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10415:     i1= pow(2,cptcoveff);
1.218     brouard  10416:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10417:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10418:                /*      k=k+1;  */
1.235     brouard  10419:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10420:     for(k=1; k<=i1;k++){
1.253     brouard  10421:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10422:        continue;
1.183     brouard  10423:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10424:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10425:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10426:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10427:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10428:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10429:       }
1.183     brouard  10430:       fprintf(ficrespij,"******\n");
                   10431:       
                   10432:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10433:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10434:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10435:        
                   10436:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10437:        
1.183     brouard  10438:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10439:        oldm=oldms;savm=savms;
1.235     brouard  10440:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10441:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10442:        for(i=1; i<=nlstate;i++)
                   10443:          for(j=1; j<=nlstate+ndeath;j++)
                   10444:            fprintf(ficrespij," %1d-%1d",i,j);
                   10445:        fprintf(ficrespij,"\n");
                   10446:        for (h=0; h<=nhstepm; h++){
                   10447:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10448:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10449:          for(i=1; i<=nlstate;i++)
                   10450:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10451:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10452:          fprintf(ficrespij,"\n");
                   10453:        }
1.183     brouard  10454:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10455:        fprintf(ficrespij,"\n");
                   10456:       }
1.180     brouard  10457:       /*}*/
                   10458:     }
1.218     brouard  10459:     return 0;
1.180     brouard  10460: }
1.218     brouard  10461:  
                   10462:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10463:     /*------------- h Bij x at various ages ------------*/
                   10464: 
                   10465:   int stepsize;
1.218     brouard  10466:   /* int agelim; */
                   10467:        int ageminl;
1.217     brouard  10468:   int hstepm;
                   10469:   int nhstepm;
1.238     brouard  10470:   int h, i, i1, j, k, nres;
1.218     brouard  10471:        
1.217     brouard  10472:   double agedeb;
                   10473:   double ***p3mat;
1.218     brouard  10474:        
                   10475:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10476:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10477:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10478:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10479:   }
                   10480:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10481:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10482:   
                   10483:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10484:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10485:   
1.218     brouard  10486:   /* agelim=AGESUP; */
                   10487:   ageminl=30;
                   10488:   hstepm=stepsize*YEARM; /* Every year of age */
                   10489:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10490:   
                   10491:   /* hstepm=1;   aff par mois*/
                   10492:   pstamp(ficrespijb);
1.255     brouard  10493:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10494:   i1= pow(2,cptcoveff);
1.218     brouard  10495:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10496:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10497:   /*   k=k+1;  */
1.238     brouard  10498:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10499:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10500:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10501:        continue;
                   10502:       fprintf(ficrespijb,"\n#****** ");
                   10503:       for(j=1;j<=cptcoveff;j++)
                   10504:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10505:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10506:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10507:       }
                   10508:       fprintf(ficrespijb,"******\n");
1.264     brouard  10509:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10510:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10511:        continue;
                   10512:       }
                   10513:       
                   10514:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10515:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10516:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10517:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10518:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10519:        
                   10520:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10521:        
1.266     brouard  10522:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10523:        /* and memory limitations if stepm is small */
                   10524: 
1.238     brouard  10525:        /* oldm=oldms;savm=savms; */
                   10526:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10527:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10528:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10529:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10530:        for(i=1; i<=nlstate;i++)
                   10531:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10532:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10533:        fprintf(ficrespijb,"\n");
1.238     brouard  10534:        for (h=0; h<=nhstepm; h++){
                   10535:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10536:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10537:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10538:          for(i=1; i<=nlstate;i++)
                   10539:            for(j=1; j<=nlstate+ndeath;j++)
                   10540:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10541:          fprintf(ficrespijb,"\n");
                   10542:        }
                   10543:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10544:        fprintf(ficrespijb,"\n");
                   10545:       } /* end age deb */
                   10546:     } /* end combination */
                   10547:   } /* end nres */
1.218     brouard  10548:   return 0;
                   10549:  } /*  hBijx */
1.217     brouard  10550: 
1.180     brouard  10551: 
1.136     brouard  10552: /***********************************************/
                   10553: /**************** Main Program *****************/
                   10554: /***********************************************/
                   10555: 
                   10556: int main(int argc, char *argv[])
                   10557: {
                   10558: #ifdef GSL
                   10559:   const gsl_multimin_fminimizer_type *T;
                   10560:   size_t iteri = 0, it;
                   10561:   int rval = GSL_CONTINUE;
                   10562:   int status = GSL_SUCCESS;
                   10563:   double ssval;
                   10564: #endif
                   10565:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10566:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10567:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10568:   int jj, ll, li, lj, lk;
1.136     brouard  10569:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10570:   int num_filled;
1.136     brouard  10571:   int itimes;
                   10572:   int NDIM=2;
                   10573:   int vpopbased=0;
1.235     brouard  10574:   int nres=0;
1.258     brouard  10575:   int endishere=0;
1.136     brouard  10576: 
1.164     brouard  10577:   char ca[32], cb[32];
1.136     brouard  10578:   /*  FILE *fichtm; *//* Html File */
                   10579:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10580:   struct stat info;
1.191     brouard  10581:   double agedeb=0.;
1.194     brouard  10582: 
                   10583:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10584:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10585: 
1.165     brouard  10586:   double fret;
1.191     brouard  10587:   double dum=0.; /* Dummy variable */
1.136     brouard  10588:   double ***p3mat;
1.218     brouard  10589:   /* double ***mobaverage; */
1.164     brouard  10590: 
                   10591:   char line[MAXLINE];
1.197     brouard  10592:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10593: 
1.234     brouard  10594:   char  modeltemp[MAXLINE];
1.230     brouard  10595:   char resultline[MAXLINE];
                   10596:   
1.136     brouard  10597:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10598:   char *tok, *val; /* pathtot */
1.136     brouard  10599:   int firstobs=1, lastobs=10;
1.195     brouard  10600:   int c,  h , cpt, c2;
1.191     brouard  10601:   int jl=0;
                   10602:   int i1, j1, jk, stepsize=0;
1.194     brouard  10603:   int count=0;
                   10604: 
1.164     brouard  10605:   int *tab; 
1.136     brouard  10606:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10607:   int backcast=0;
1.136     brouard  10608:   int mobilav=0,popforecast=0;
1.191     brouard  10609:   int hstepm=0, nhstepm=0;
1.136     brouard  10610:   int agemortsup;
                   10611:   float  sumlpop=0.;
                   10612:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10613:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10614: 
1.191     brouard  10615:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10616:   double ftolpl=FTOL;
                   10617:   double **prlim;
1.217     brouard  10618:   double **bprlim;
1.136     brouard  10619:   double ***param; /* Matrix of parameters */
1.251     brouard  10620:   double ***paramstart; /* Matrix of starting parameter values */
                   10621:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10622:   double **matcov; /* Matrix of covariance */
1.203     brouard  10623:   double **hess; /* Hessian matrix */
1.136     brouard  10624:   double ***delti3; /* Scale */
                   10625:   double *delti; /* Scale */
                   10626:   double ***eij, ***vareij;
                   10627:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10628: 
1.136     brouard  10629:   double *epj, vepp;
1.164     brouard  10630: 
1.136     brouard  10631:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  10632:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   10633: 
1.136     brouard  10634:   double **ximort;
1.145     brouard  10635:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10636:   int *dcwave;
                   10637: 
1.164     brouard  10638:   char z[1]="c";
1.136     brouard  10639: 
                   10640:   /*char  *strt;*/
                   10641:   char strtend[80];
1.126     brouard  10642: 
1.164     brouard  10643: 
1.126     brouard  10644: /*   setlocale (LC_ALL, ""); */
                   10645: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10646: /*   textdomain (PACKAGE); */
                   10647: /*   setlocale (LC_CTYPE, ""); */
                   10648: /*   setlocale (LC_MESSAGES, ""); */
                   10649: 
                   10650:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10651:   rstart_time = time(NULL);  
                   10652:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10653:   start_time = *localtime(&rstart_time);
1.126     brouard  10654:   curr_time=start_time;
1.157     brouard  10655:   /*tml = *localtime(&start_time.tm_sec);*/
                   10656:   /* strcpy(strstart,asctime(&tml)); */
                   10657:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10658: 
                   10659: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10660: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10661: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10662: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10663: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10664: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10665: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10666: /*   strt=asctime(&tmg); */
                   10667: /*   printf("Time(after) =%s",strstart);  */
                   10668: /*  (void) time (&time_value);
                   10669: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10670: *  tm = *localtime(&time_value);
                   10671: *  strstart=asctime(&tm);
                   10672: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10673: */
                   10674: 
                   10675:   nberr=0; /* Number of errors and warnings */
                   10676:   nbwarn=0;
1.184     brouard  10677: #ifdef WIN32
                   10678:   _getcwd(pathcd, size);
                   10679: #else
1.126     brouard  10680:   getcwd(pathcd, size);
1.184     brouard  10681: #endif
1.191     brouard  10682:   syscompilerinfo(0);
1.196     brouard  10683:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10684:   if(argc <=1){
                   10685:     printf("\nEnter the parameter file name: ");
1.205     brouard  10686:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10687:       printf("ERROR Empty parameter file name\n");
                   10688:       goto end;
                   10689:     }
1.126     brouard  10690:     i=strlen(pathr);
                   10691:     if(pathr[i-1]=='\n')
                   10692:       pathr[i-1]='\0';
1.156     brouard  10693:     i=strlen(pathr);
1.205     brouard  10694:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10695:       pathr[i-1]='\0';
1.205     brouard  10696:     }
                   10697:     i=strlen(pathr);
                   10698:     if( i==0 ){
                   10699:       printf("ERROR Empty parameter file name\n");
                   10700:       goto end;
                   10701:     }
                   10702:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10703:       printf("Pathr |%s|\n",pathr);
                   10704:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10705:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10706:       strcpy (pathtot, val);
                   10707:       if(pathr[0] == '\0') break; /* Dirty */
                   10708:     }
                   10709:   }
                   10710:   else{
                   10711:     strcpy(pathtot,argv[1]);
                   10712:   }
                   10713:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10714:   /*cygwin_split_path(pathtot,path,optionfile);
                   10715:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10716:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10717: 
                   10718:   /* Split argv[0], imach program to get pathimach */
                   10719:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10720:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10721:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10722:  /*   strcpy(pathimach,argv[0]); */
                   10723:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10724:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10725:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10726: #ifdef WIN32
                   10727:   _chdir(path); /* Can be a relative path */
                   10728:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10729: #else
1.126     brouard  10730:   chdir(path); /* Can be a relative path */
1.184     brouard  10731:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10732: #endif
                   10733:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10734:   strcpy(command,"mkdir ");
                   10735:   strcat(command,optionfilefiname);
                   10736:   if((outcmd=system(command)) != 0){
1.169     brouard  10737:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10738:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10739:     /* fclose(ficlog); */
                   10740: /*     exit(1); */
                   10741:   }
                   10742: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10743: /*     perror("mkdir"); */
                   10744: /*   } */
                   10745: 
                   10746:   /*-------- arguments in the command line --------*/
                   10747: 
1.186     brouard  10748:   /* Main Log file */
1.126     brouard  10749:   strcat(filelog, optionfilefiname);
                   10750:   strcat(filelog,".log");    /* */
                   10751:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10752:     printf("Problem with logfile %s\n",filelog);
                   10753:     goto end;
                   10754:   }
                   10755:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10756:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10757:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10758:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10759:  path=%s \n\
                   10760:  optionfile=%s\n\
                   10761:  optionfilext=%s\n\
1.156     brouard  10762:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10763: 
1.197     brouard  10764:   syscompilerinfo(1);
1.167     brouard  10765: 
1.126     brouard  10766:   printf("Local time (at start):%s",strstart);
                   10767:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10768:   fflush(ficlog);
                   10769: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10770: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10771: 
                   10772:   /* */
                   10773:   strcpy(fileres,"r");
                   10774:   strcat(fileres, optionfilefiname);
1.201     brouard  10775:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10776:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10777:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10778: 
1.186     brouard  10779:   /* Main ---------arguments file --------*/
1.126     brouard  10780: 
                   10781:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10782:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10783:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10784:     fflush(ficlog);
1.149     brouard  10785:     /* goto end; */
                   10786:     exit(70); 
1.126     brouard  10787:   }
                   10788: 
                   10789: 
                   10790: 
                   10791:   strcpy(filereso,"o");
1.201     brouard  10792:   strcat(filereso,fileresu);
1.126     brouard  10793:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10794:     printf("Problem with Output resultfile: %s\n", filereso);
                   10795:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10796:     fflush(ficlog);
                   10797:     goto end;
                   10798:   }
                   10799: 
                   10800:   /* Reads comments: lines beginning with '#' */
                   10801:   numlinepar=0;
1.197     brouard  10802: 
                   10803:     /* First parameter line */
                   10804:   while(fgets(line, MAXLINE, ficpar)) {
                   10805:     /* If line starts with a # it is a comment */
                   10806:     if (line[0] == '#') {
                   10807:       numlinepar++;
                   10808:       fputs(line,stdout);
                   10809:       fputs(line,ficparo);
                   10810:       fputs(line,ficlog);
                   10811:       continue;
                   10812:     }else
                   10813:       break;
                   10814:   }
                   10815:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10816:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10817:     if (num_filled != 5) {
                   10818:       printf("Should be 5 parameters\n");
                   10819:     }
1.126     brouard  10820:     numlinepar++;
1.197     brouard  10821:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10822:   }
                   10823:   /* Second parameter line */
                   10824:   while(fgets(line, MAXLINE, ficpar)) {
                   10825:     /* If line starts with a # it is a comment */
                   10826:     if (line[0] == '#') {
                   10827:       numlinepar++;
                   10828:       fputs(line,stdout);
                   10829:       fputs(line,ficparo);
                   10830:       fputs(line,ficlog);
                   10831:       continue;
                   10832:     }else
                   10833:       break;
                   10834:   }
1.223     brouard  10835:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10836:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10837:     if (num_filled != 11) {
                   10838:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10839:       printf("but line=%s\n",line);
1.197     brouard  10840:     }
1.223     brouard  10841:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10842:   }
1.203     brouard  10843:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10844:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10845:   /* Third parameter line */
                   10846:   while(fgets(line, MAXLINE, ficpar)) {
                   10847:     /* If line starts with a # it is a comment */
                   10848:     if (line[0] == '#') {
                   10849:       numlinepar++;
                   10850:       fputs(line,stdout);
                   10851:       fputs(line,ficparo);
                   10852:       fputs(line,ficlog);
                   10853:       continue;
                   10854:     }else
                   10855:       break;
                   10856:   }
1.201     brouard  10857:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10858:     if (num_filled == 0){
                   10859:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10860:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10861:       model[0]='\0';
                   10862:       goto end;
                   10863:     } else if (num_filled != 1){
1.197     brouard  10864:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10865:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10866:       model[0]='\0';
                   10867:       goto end;
                   10868:     }
                   10869:     else{
                   10870:       if (model[0]=='+'){
                   10871:        for(i=1; i<=strlen(model);i++)
                   10872:          modeltemp[i-1]=model[i];
1.201     brouard  10873:        strcpy(model,modeltemp); 
1.197     brouard  10874:       }
                   10875:     }
1.199     brouard  10876:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10877:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10878:   }
                   10879:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10880:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10881:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10882:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10883:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10884:   fflush(ficlog);
1.190     brouard  10885:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10886:   if(model[0]=='#'){
1.187     brouard  10887:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10888:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10889:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10890:     if(mle != -1){
                   10891:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10892:       exit(1);
                   10893:     }
                   10894:   }
1.126     brouard  10895:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10896:     ungetc(c,ficpar);
                   10897:     fgets(line, MAXLINE, ficpar);
                   10898:     numlinepar++;
1.195     brouard  10899:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10900:       z[0]=line[1];
                   10901:     }
                   10902:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10903:     fputs(line, stdout);
                   10904:     //puts(line);
1.126     brouard  10905:     fputs(line,ficparo);
                   10906:     fputs(line,ficlog);
                   10907:   }
                   10908:   ungetc(c,ficpar);
                   10909: 
                   10910:    
1.145     brouard  10911:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10912:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10913:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10914:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10915:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10916:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10917:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10918:   */
                   10919:   if (strlen(model)>1) 
1.187     brouard  10920:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10921:   else
1.187     brouard  10922:     ncovmodel=2; /* Constant and age */
1.133     brouard  10923:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10924:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10925:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10926:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10927:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10928:     fflush(stdout);
                   10929:     fclose (ficlog);
                   10930:     goto end;
                   10931:   }
1.126     brouard  10932:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10933:   delti=delti3[1][1];
                   10934:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10935:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10936: /* We could also provide initial parameters values giving by simple logistic regression 
                   10937:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10938:       /* for(i=1;i<nlstate;i++){ */
                   10939:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10940:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10941:       /* } */
1.126     brouard  10942:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10943:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10944:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10945:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10946:     fclose (ficparo);
                   10947:     fclose (ficlog);
                   10948:     goto end;
                   10949:     exit(0);
1.220     brouard  10950:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10951:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10952:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10953:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10954:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10955:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10956:     hess=matrix(1,npar,1,npar);
1.220     brouard  10957:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10958:     /* Read guessed parameters */
1.126     brouard  10959:     /* Reads comments: lines beginning with '#' */
                   10960:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10961:       ungetc(c,ficpar);
                   10962:       fgets(line, MAXLINE, ficpar);
                   10963:       numlinepar++;
1.141     brouard  10964:       fputs(line,stdout);
1.126     brouard  10965:       fputs(line,ficparo);
                   10966:       fputs(line,ficlog);
                   10967:     }
                   10968:     ungetc(c,ficpar);
                   10969:     
                   10970:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10971:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10972:     for(i=1; i <=nlstate; i++){
1.234     brouard  10973:       j=0;
1.126     brouard  10974:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10975:        if(jj==i) continue;
                   10976:        j++;
                   10977:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10978:        if ((i1 != i) || (j1 != jj)){
                   10979:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10980: It might be a problem of design; if ncovcol and the model are correct\n \
                   10981: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10982:          exit(1);
                   10983:        }
                   10984:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10985:        if(mle==1)
                   10986:          printf("%1d%1d",i,jj);
                   10987:        fprintf(ficlog,"%1d%1d",i,jj);
                   10988:        for(k=1; k<=ncovmodel;k++){
                   10989:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10990:          if(mle==1){
                   10991:            printf(" %lf",param[i][j][k]);
                   10992:            fprintf(ficlog," %lf",param[i][j][k]);
                   10993:          }
                   10994:          else
                   10995:            fprintf(ficlog," %lf",param[i][j][k]);
                   10996:          fprintf(ficparo," %lf",param[i][j][k]);
                   10997:        }
                   10998:        fscanf(ficpar,"\n");
                   10999:        numlinepar++;
                   11000:        if(mle==1)
                   11001:          printf("\n");
                   11002:        fprintf(ficlog,"\n");
                   11003:        fprintf(ficparo,"\n");
1.126     brouard  11004:       }
                   11005:     }  
                   11006:     fflush(ficlog);
1.234     brouard  11007:     
1.251     brouard  11008:     /* Reads parameters values */
1.126     brouard  11009:     p=param[1][1];
1.251     brouard  11010:     pstart=paramstart[1][1];
1.126     brouard  11011:     
                   11012:     /* Reads comments: lines beginning with '#' */
                   11013:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11014:       ungetc(c,ficpar);
                   11015:       fgets(line, MAXLINE, ficpar);
                   11016:       numlinepar++;
1.141     brouard  11017:       fputs(line,stdout);
1.126     brouard  11018:       fputs(line,ficparo);
                   11019:       fputs(line,ficlog);
                   11020:     }
                   11021:     ungetc(c,ficpar);
                   11022: 
                   11023:     for(i=1; i <=nlstate; i++){
                   11024:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11025:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11026:        if ( (i1-i) * (j1-j) != 0){
                   11027:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11028:          exit(1);
                   11029:        }
                   11030:        printf("%1d%1d",i,j);
                   11031:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11032:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11033:        for(k=1; k<=ncovmodel;k++){
                   11034:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11035:          printf(" %le",delti3[i][j][k]);
                   11036:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11037:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11038:        }
                   11039:        fscanf(ficpar,"\n");
                   11040:        numlinepar++;
                   11041:        printf("\n");
                   11042:        fprintf(ficparo,"\n");
                   11043:        fprintf(ficlog,"\n");
1.126     brouard  11044:       }
                   11045:     }
                   11046:     fflush(ficlog);
1.234     brouard  11047:     
1.145     brouard  11048:     /* Reads covariance matrix */
1.126     brouard  11049:     delti=delti3[1][1];
1.220     brouard  11050:                
                   11051:                
1.126     brouard  11052:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11053:                
1.126     brouard  11054:     /* Reads comments: lines beginning with '#' */
                   11055:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11056:       ungetc(c,ficpar);
                   11057:       fgets(line, MAXLINE, ficpar);
                   11058:       numlinepar++;
1.141     brouard  11059:       fputs(line,stdout);
1.126     brouard  11060:       fputs(line,ficparo);
                   11061:       fputs(line,ficlog);
                   11062:     }
                   11063:     ungetc(c,ficpar);
1.220     brouard  11064:                
1.126     brouard  11065:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11066:     hess=matrix(1,npar,1,npar);
1.131     brouard  11067:     for(i=1; i <=npar; i++)
                   11068:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11069:                
1.194     brouard  11070:     /* Scans npar lines */
1.126     brouard  11071:     for(i=1; i <=npar; i++){
1.226     brouard  11072:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11073:       if(count != 3){
1.226     brouard  11074:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11075: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11076: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11077:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11078: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11079: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11080:        exit(1);
1.220     brouard  11081:       }else{
1.226     brouard  11082:        if(mle==1)
                   11083:          printf("%1d%1d%d",i1,j1,jk);
                   11084:       }
                   11085:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11086:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11087:       for(j=1; j <=i; j++){
1.226     brouard  11088:        fscanf(ficpar," %le",&matcov[i][j]);
                   11089:        if(mle==1){
                   11090:          printf(" %.5le",matcov[i][j]);
                   11091:        }
                   11092:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11093:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11094:       }
                   11095:       fscanf(ficpar,"\n");
                   11096:       numlinepar++;
                   11097:       if(mle==1)
1.220     brouard  11098:                                printf("\n");
1.126     brouard  11099:       fprintf(ficlog,"\n");
                   11100:       fprintf(ficparo,"\n");
                   11101:     }
1.194     brouard  11102:     /* End of read covariance matrix npar lines */
1.126     brouard  11103:     for(i=1; i <=npar; i++)
                   11104:       for(j=i+1;j<=npar;j++)
1.226     brouard  11105:        matcov[i][j]=matcov[j][i];
1.126     brouard  11106:     
                   11107:     if(mle==1)
                   11108:       printf("\n");
                   11109:     fprintf(ficlog,"\n");
                   11110:     
                   11111:     fflush(ficlog);
                   11112:     
                   11113:     /*-------- Rewriting parameter file ----------*/
                   11114:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11115:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11116:     strcat(rfileres,".");    /* */
                   11117:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11118:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11119:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11120:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11121:     }
                   11122:     fprintf(ficres,"#%s\n",version);
                   11123:   }    /* End of mle != -3 */
1.218     brouard  11124:   
1.186     brouard  11125:   /*  Main data
                   11126:    */
1.126     brouard  11127:   n= lastobs;
                   11128:   num=lvector(1,n);
                   11129:   moisnais=vector(1,n);
                   11130:   annais=vector(1,n);
                   11131:   moisdc=vector(1,n);
                   11132:   andc=vector(1,n);
1.220     brouard  11133:   weight=vector(1,n);
1.126     brouard  11134:   agedc=vector(1,n);
                   11135:   cod=ivector(1,n);
1.220     brouard  11136:   for(i=1;i<=n;i++){
1.234     brouard  11137:     num[i]=0;
                   11138:     moisnais[i]=0;
                   11139:     annais[i]=0;
                   11140:     moisdc[i]=0;
                   11141:     andc[i]=0;
                   11142:     agedc[i]=0;
                   11143:     cod[i]=0;
                   11144:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11145:   }
1.126     brouard  11146:   mint=matrix(1,maxwav,1,n);
                   11147:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11148:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11149:   tab=ivector(1,NCOVMAX);
1.144     brouard  11150:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11151:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11152: 
1.136     brouard  11153:   /* Reads data from file datafile */
                   11154:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11155:     goto end;
                   11156: 
                   11157:   /* Calculation of the number of parameters from char model */
1.234     brouard  11158:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11159:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11160:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11161:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11162:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11163:   */
                   11164:   
                   11165:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11166:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11167:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11168:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11169:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11170:   TvarF=ivector(1,NCOVMAX); /*  */
                   11171:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11172:   TvarV=ivector(1,NCOVMAX); /*  */
                   11173:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11174:   TvarA=ivector(1,NCOVMAX); /*  */
                   11175:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11176:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11177:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11178:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11179:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11180:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11181:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11182:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11183:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11184: 
1.230     brouard  11185:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11186:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11187:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11188:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11189:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11190:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11191:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11192:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11193:   */
                   11194:   /* For model-covariate k tells which data-covariate to use but
                   11195:     because this model-covariate is a construction we invent a new column
                   11196:     ncovcol + k1
                   11197:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11198:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11199:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11200:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11201:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11202:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11203:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11204:   */
1.145     brouard  11205:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11206:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11207:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11208:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11209:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11210:                         4 covariates (3 plus signs)
                   11211:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11212:                      */  
1.230     brouard  11213:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11214:                                * individual dummy, fixed or varying:
                   11215:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11216:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11217:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11218:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11219:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11220:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11221:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11222:                                * individual quantitative, fixed or varying:
                   11223:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11224:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11225:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11226: /* Main decodemodel */
                   11227: 
1.187     brouard  11228: 
1.223     brouard  11229:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11230:     goto end;
                   11231: 
1.137     brouard  11232:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11233:     nbwarn++;
                   11234:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11235:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11236:   }
1.136     brouard  11237:     /*  if(mle==1){*/
1.137     brouard  11238:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11239:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11240:   }
                   11241: 
                   11242:     /*-calculation of age at interview from date of interview and age at death -*/
                   11243:   agev=matrix(1,maxwav,1,imx);
                   11244: 
                   11245:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11246:     goto end;
                   11247: 
1.126     brouard  11248: 
1.136     brouard  11249:   agegomp=(int)agemin;
                   11250:   free_vector(moisnais,1,n);
                   11251:   free_vector(annais,1,n);
1.126     brouard  11252:   /* free_matrix(mint,1,maxwav,1,n);
                   11253:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11254:   /* free_vector(moisdc,1,n); */
                   11255:   /* free_vector(andc,1,n); */
1.145     brouard  11256:   /* */
                   11257:   
1.126     brouard  11258:   wav=ivector(1,imx);
1.214     brouard  11259:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11260:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11261:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11262:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11263:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11264:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11265:    
                   11266:   /* Concatenates waves */
1.214     brouard  11267:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11268:      Death is a valid wave (if date is known).
                   11269:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11270:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11271:      and mw[mi+1][i]. dh depends on stepm.
                   11272:   */
                   11273: 
1.126     brouard  11274:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11275:   /* Concatenates waves */
1.145     brouard  11276:  
1.215     brouard  11277:   free_vector(moisdc,1,n);
                   11278:   free_vector(andc,1,n);
                   11279: 
1.126     brouard  11280:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11281:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11282:   ncodemax[1]=1;
1.145     brouard  11283:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11284:   cptcoveff=0;
1.220     brouard  11285:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11286:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11287:   }
                   11288:   
                   11289:   ncovcombmax=pow(2,cptcoveff);
                   11290:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11291:   for(i=1;i<ncovcombmax;i++)
                   11292:     invalidvarcomb[i]=0;
                   11293:   
1.211     brouard  11294:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11295:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11296:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11297:   
1.200     brouard  11298:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11299:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11300:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11301:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11302:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11303:    * (currently 0 or 1) in the data.
                   11304:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11305:    * corresponding modality (h,j).
                   11306:    */
                   11307: 
1.145     brouard  11308:   h=0;
                   11309:   /*if (cptcovn > 0) */
1.126     brouard  11310:   m=pow(2,cptcoveff);
                   11311:  
1.144     brouard  11312:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11313:           * For k=4 covariates, h goes from 1 to m=2**k
                   11314:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11315:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11316:           *     h\k   1     2     3     4
1.143     brouard  11317:           *______________________________  
                   11318:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11319:           *     2     2     1     1     1
                   11320:           *     3 i=2 1     2     1     1
                   11321:           *     4     2     2     1     1
                   11322:           *     5 i=3 1 i=2 1     2     1
                   11323:           *     6     2     1     2     1
                   11324:           *     7 i=4 1     2     2     1
                   11325:           *     8     2     2     2     1
1.197     brouard  11326:           *     9 i=5 1 i=3 1 i=2 1     2
                   11327:           *    10     2     1     1     2
                   11328:           *    11 i=6 1     2     1     2
                   11329:           *    12     2     2     1     2
                   11330:           *    13 i=7 1 i=4 1     2     2    
                   11331:           *    14     2     1     2     2
                   11332:           *    15 i=8 1     2     2     2
                   11333:           *    16     2     2     2     2
1.143     brouard  11334:           */
1.212     brouard  11335:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11336:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11337:      * and the value of each covariate?
                   11338:      * V1=1, V2=1, V3=2, V4=1 ?
                   11339:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11340:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11341:      * In order to get the real value in the data, we use nbcode
                   11342:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11343:      * We are keeping this crazy system in order to be able (in the future?) 
                   11344:      * to have more than 2 values (0 or 1) for a covariate.
                   11345:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11346:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11347:      *              bbbbbbbb
                   11348:      *              76543210     
                   11349:      *   h-1        00000101 (6-1=5)
1.219     brouard  11350:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11351:      *           &
                   11352:      *     1        00000001 (1)
1.219     brouard  11353:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11354:      *          +1= 00000001 =1 
1.211     brouard  11355:      *
                   11356:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11357:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11358:      *    >>k'            11
                   11359:      *          &   00000001
                   11360:      *            = 00000001
                   11361:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11362:      * Reverse h=6 and m=16?
                   11363:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11364:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11365:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11366:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11367:      * V3=decodtabm(14,3,2**4)=2
                   11368:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11369:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11370:      *          &1 000000001
                   11371:      *           = 000000001
                   11372:      *         +1= 000000010 =2
                   11373:      *                  2211
                   11374:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11375:      *                  V3=2
1.220     brouard  11376:                 * codtabm and decodtabm are identical
1.211     brouard  11377:      */
                   11378: 
1.145     brouard  11379: 
                   11380:  free_ivector(Ndum,-1,NCOVMAX);
                   11381: 
                   11382: 
1.126     brouard  11383:     
1.186     brouard  11384:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11385:   strcpy(optionfilegnuplot,optionfilefiname);
                   11386:   if(mle==-3)
1.201     brouard  11387:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11388:   strcat(optionfilegnuplot,".gp");
                   11389: 
                   11390:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11391:     printf("Problem with file %s",optionfilegnuplot);
                   11392:   }
                   11393:   else{
1.204     brouard  11394:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11395:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11396:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11397:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11398:   }
                   11399:   /*  fclose(ficgp);*/
1.186     brouard  11400: 
                   11401: 
                   11402:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11403: 
                   11404:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11405:   if(mle==-3)
1.201     brouard  11406:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11407:   strcat(optionfilehtm,".htm");
                   11408:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11409:     printf("Problem with %s \n",optionfilehtm);
                   11410:     exit(0);
1.126     brouard  11411:   }
                   11412: 
                   11413:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11414:   strcat(optionfilehtmcov,"-cov.htm");
                   11415:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11416:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11417:   }
                   11418:   else{
                   11419:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11420: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11421: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11422:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11423:   }
                   11424: 
1.213     brouard  11425:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11426: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11427: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11428: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11429: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11430: \n\
                   11431: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11432:  <ul><li><h4>Parameter files</h4>\n\
                   11433:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11434:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11435:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11436:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11437:  - Date and time at start: %s</ul>\n",\
                   11438:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11439:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11440:          fileres,fileres,\
                   11441:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11442:   fflush(fichtm);
                   11443: 
                   11444:   strcpy(pathr,path);
                   11445:   strcat(pathr,optionfilefiname);
1.184     brouard  11446: #ifdef WIN32
                   11447:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11448: #else
1.126     brouard  11449:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11450: #endif
                   11451:          
1.126     brouard  11452:   
1.220     brouard  11453:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11454:                 and for any valid combination of covariates
1.126     brouard  11455:      and prints on file fileres'p'. */
1.251     brouard  11456:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11457:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11458: 
                   11459:   fprintf(fichtm,"\n");
                   11460:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   11461: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11462: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   11463:          imx,agemin,agemax,jmin,jmax,jmean);
                   11464:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11465:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11466:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11467:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11468:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11469: 
1.126     brouard  11470:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11471:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11472:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11473: 
                   11474:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11475:   /* For mortality only */
1.126     brouard  11476:   if (mle==-3){
1.136     brouard  11477:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11478:     for(i=1;i<=NDIM;i++)
                   11479:       for(j=1;j<=NDIM;j++)
                   11480:        ximort[i][j]=0.;
1.186     brouard  11481:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11482:     cens=ivector(1,n);
                   11483:     ageexmed=vector(1,n);
                   11484:     agecens=vector(1,n);
                   11485:     dcwave=ivector(1,n);
1.223     brouard  11486:                
1.126     brouard  11487:     for (i=1; i<=imx; i++){
                   11488:       dcwave[i]=-1;
                   11489:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11490:        if (s[m][i]>nlstate) {
                   11491:          dcwave[i]=m;
                   11492:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11493:          break;
                   11494:        }
1.126     brouard  11495:     }
1.226     brouard  11496:     
1.126     brouard  11497:     for (i=1; i<=imx; i++) {
                   11498:       if (wav[i]>0){
1.226     brouard  11499:        ageexmed[i]=agev[mw[1][i]][i];
                   11500:        j=wav[i];
                   11501:        agecens[i]=1.; 
                   11502:        
                   11503:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11504:          agecens[i]=agev[mw[j][i]][i];
                   11505:          cens[i]= 1;
                   11506:        }else if (ageexmed[i]< 1) 
                   11507:          cens[i]= -1;
                   11508:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11509:          cens[i]=0 ;
1.126     brouard  11510:       }
                   11511:       else cens[i]=-1;
                   11512:     }
                   11513:     
                   11514:     for (i=1;i<=NDIM;i++) {
                   11515:       for (j=1;j<=NDIM;j++)
1.226     brouard  11516:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11517:     }
                   11518:     
1.145     brouard  11519:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11520:     /*printf("%lf %lf", p[1], p[2]);*/
                   11521:     
                   11522:     
1.136     brouard  11523: #ifdef GSL
                   11524:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11525: #else
1.126     brouard  11526:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11527: #endif
1.201     brouard  11528:     strcpy(filerespow,"POW-MORT_"); 
                   11529:     strcat(filerespow,fileresu);
1.126     brouard  11530:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11531:       printf("Problem with resultfile: %s\n", filerespow);
                   11532:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11533:     }
1.136     brouard  11534: #ifdef GSL
                   11535:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11536: #else
1.126     brouard  11537:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11538: #endif
1.126     brouard  11539:     /*  for (i=1;i<=nlstate;i++)
                   11540:        for(j=1;j<=nlstate+ndeath;j++)
                   11541:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11542:     */
                   11543:     fprintf(ficrespow,"\n");
1.136     brouard  11544: #ifdef GSL
                   11545:     /* gsl starts here */ 
                   11546:     T = gsl_multimin_fminimizer_nmsimplex;
                   11547:     gsl_multimin_fminimizer *sfm = NULL;
                   11548:     gsl_vector *ss, *x;
                   11549:     gsl_multimin_function minex_func;
                   11550: 
                   11551:     /* Initial vertex size vector */
                   11552:     ss = gsl_vector_alloc (NDIM);
                   11553:     
                   11554:     if (ss == NULL){
                   11555:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11556:     }
                   11557:     /* Set all step sizes to 1 */
                   11558:     gsl_vector_set_all (ss, 0.001);
                   11559: 
                   11560:     /* Starting point */
1.126     brouard  11561:     
1.136     brouard  11562:     x = gsl_vector_alloc (NDIM);
                   11563:     
                   11564:     if (x == NULL){
                   11565:       gsl_vector_free(ss);
                   11566:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11567:     }
                   11568:   
                   11569:     /* Initialize method and iterate */
                   11570:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11571:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11572:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11573:     gsl_vector_set(x, 0, p[1]);
                   11574:     gsl_vector_set(x, 1, p[2]);
                   11575: 
                   11576:     minex_func.f = &gompertz_f;
                   11577:     minex_func.n = NDIM;
                   11578:     minex_func.params = (void *)&p; /* ??? */
                   11579:     
                   11580:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11581:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11582:     
                   11583:     printf("Iterations beginning .....\n\n");
                   11584:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11585: 
                   11586:     iteri=0;
                   11587:     while (rval == GSL_CONTINUE){
                   11588:       iteri++;
                   11589:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11590:       
                   11591:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11592:       fflush(0);
                   11593:       
                   11594:       if (status) 
                   11595:         break;
                   11596:       
                   11597:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11598:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11599:       
                   11600:       if (rval == GSL_SUCCESS)
                   11601:         printf ("converged to a local maximum at\n");
                   11602:       
                   11603:       printf("%5d ", iteri);
                   11604:       for (it = 0; it < NDIM; it++){
                   11605:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11606:       }
                   11607:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11608:     }
                   11609:     
                   11610:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11611:     
                   11612:     gsl_vector_free(x); /* initial values */
                   11613:     gsl_vector_free(ss); /* inital step size */
                   11614:     for (it=0; it<NDIM; it++){
                   11615:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11616:       fprintf(ficrespow," %.12lf", p[it]);
                   11617:     }
                   11618:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11619: #endif
                   11620: #ifdef POWELL
                   11621:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11622: #endif  
1.126     brouard  11623:     fclose(ficrespow);
                   11624:     
1.203     brouard  11625:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11626: 
                   11627:     for(i=1; i <=NDIM; i++)
                   11628:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11629:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11630:     
                   11631:     printf("\nCovariance matrix\n ");
1.203     brouard  11632:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11633:     for(i=1; i <=NDIM; i++) {
                   11634:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11635:                                printf("%f ",matcov[i][j]);
                   11636:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11637:       }
1.203     brouard  11638:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11639:     }
                   11640:     
                   11641:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11642:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11643:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11644:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11645:     }
1.126     brouard  11646:     lsurv=vector(1,AGESUP);
                   11647:     lpop=vector(1,AGESUP);
                   11648:     tpop=vector(1,AGESUP);
                   11649:     lsurv[agegomp]=100000;
                   11650:     
                   11651:     for (k=agegomp;k<=AGESUP;k++) {
                   11652:       agemortsup=k;
                   11653:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11654:     }
                   11655:     
                   11656:     for (k=agegomp;k<agemortsup;k++)
                   11657:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11658:     
                   11659:     for (k=agegomp;k<agemortsup;k++){
                   11660:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11661:       sumlpop=sumlpop+lpop[k];
                   11662:     }
                   11663:     
                   11664:     tpop[agegomp]=sumlpop;
                   11665:     for (k=agegomp;k<(agemortsup-3);k++){
                   11666:       /*  tpop[k+1]=2;*/
                   11667:       tpop[k+1]=tpop[k]-lpop[k];
                   11668:     }
                   11669:     
                   11670:     
                   11671:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11672:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11673:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11674:     
                   11675:     
                   11676:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11677:                ageminpar=50;
                   11678:                agemaxpar=100;
1.194     brouard  11679:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11680:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11681: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11682: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11683:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11684: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11685: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11686:     }else{
                   11687:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11688:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11689:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11690:                }
1.201     brouard  11691:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11692:                     stepm, weightopt,\
                   11693:                     model,imx,p,matcov,agemortsup);
                   11694:     
                   11695:     free_vector(lsurv,1,AGESUP);
                   11696:     free_vector(lpop,1,AGESUP);
                   11697:     free_vector(tpop,1,AGESUP);
1.220     brouard  11698:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11699:     free_ivector(cens,1,n);
                   11700:     free_vector(agecens,1,n);
                   11701:     free_ivector(dcwave,1,n);
1.220     brouard  11702: #ifdef GSL
1.136     brouard  11703: #endif
1.186     brouard  11704:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11705:   /* Standard  */
                   11706:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11707:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11708:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11709:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11710:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11711:     for (k=1; k<=npar;k++)
                   11712:       printf(" %d %8.5f",k,p[k]);
                   11713:     printf("\n");
1.205     brouard  11714:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11715:       /* mlikeli uses func not funcone */
1.247     brouard  11716:       /* for(i=1;i<nlstate;i++){ */
                   11717:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11718:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11719:       /* } */
1.205     brouard  11720:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11721:     }
                   11722:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11723:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11724:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11725:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11726:     }
                   11727:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11728:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11729:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11730:     for (k=1; k<=npar;k++)
                   11731:       printf(" %d %8.5f",k,p[k]);
                   11732:     printf("\n");
                   11733:     
                   11734:     /*--------- results files --------------*/
1.224     brouard  11735:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11736:     
                   11737:     
                   11738:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11739:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11740:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11741:     for(i=1,jk=1; i <=nlstate; i++){
                   11742:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11743:        if (k != i) {
                   11744:          printf("%d%d ",i,k);
                   11745:          fprintf(ficlog,"%d%d ",i,k);
                   11746:          fprintf(ficres,"%1d%1d ",i,k);
                   11747:          for(j=1; j <=ncovmodel; j++){
                   11748:            printf("%12.7f ",p[jk]);
                   11749:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11750:            fprintf(ficres,"%12.7f ",p[jk]);
                   11751:            jk++; 
                   11752:          }
                   11753:          printf("\n");
                   11754:          fprintf(ficlog,"\n");
                   11755:          fprintf(ficres,"\n");
                   11756:        }
1.126     brouard  11757:       }
                   11758:     }
1.203     brouard  11759:     if(mle != 0){
                   11760:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11761:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11762:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11763:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11764:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11765:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11766:        for(k=1; k <=(nlstate+ndeath); k++){
                   11767:          if (k != i) {
                   11768:            printf("%d%d ",i,k);
                   11769:            fprintf(ficlog,"%d%d ",i,k);
                   11770:            for(j=1; j <=ncovmodel; j++){
                   11771:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11772:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11773:              jk++; 
                   11774:            }
                   11775:            printf("\n");
                   11776:            fprintf(ficlog,"\n");
                   11777:          }
                   11778:        }
1.193     brouard  11779:       }
1.203     brouard  11780:     } /* end of hesscov and Wald tests */
1.225     brouard  11781:     
1.203     brouard  11782:     /*  */
1.126     brouard  11783:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11784:     printf("# Scales (for hessian or gradient estimation)\n");
                   11785:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11786:     for(i=1,jk=1; i <=nlstate; i++){
                   11787:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11788:        if (j!=i) {
                   11789:          fprintf(ficres,"%1d%1d",i,j);
                   11790:          printf("%1d%1d",i,j);
                   11791:          fprintf(ficlog,"%1d%1d",i,j);
                   11792:          for(k=1; k<=ncovmodel;k++){
                   11793:            printf(" %.5e",delti[jk]);
                   11794:            fprintf(ficlog," %.5e",delti[jk]);
                   11795:            fprintf(ficres," %.5e",delti[jk]);
                   11796:            jk++;
                   11797:          }
                   11798:          printf("\n");
                   11799:          fprintf(ficlog,"\n");
                   11800:          fprintf(ficres,"\n");
                   11801:        }
1.126     brouard  11802:       }
                   11803:     }
                   11804:     
                   11805:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11806:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11807:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11808:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11809:     /* # 121 Var(a12)\n\ */
                   11810:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11811:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11812:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11813:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11814:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11815:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11816:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11817:     
                   11818:     
                   11819:     /* Just to have a covariance matrix which will be more understandable
                   11820:        even is we still don't want to manage dictionary of variables
                   11821:     */
                   11822:     for(itimes=1;itimes<=2;itimes++){
                   11823:       jj=0;
                   11824:       for(i=1; i <=nlstate; i++){
1.225     brouard  11825:        for(j=1; j <=nlstate+ndeath; j++){
                   11826:          if(j==i) continue;
                   11827:          for(k=1; k<=ncovmodel;k++){
                   11828:            jj++;
                   11829:            ca[0]= k+'a'-1;ca[1]='\0';
                   11830:            if(itimes==1){
                   11831:              if(mle>=1)
                   11832:                printf("#%1d%1d%d",i,j,k);
                   11833:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11834:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11835:            }else{
                   11836:              if(mle>=1)
                   11837:                printf("%1d%1d%d",i,j,k);
                   11838:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11839:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11840:            }
                   11841:            ll=0;
                   11842:            for(li=1;li <=nlstate; li++){
                   11843:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11844:                if(lj==li) continue;
                   11845:                for(lk=1;lk<=ncovmodel;lk++){
                   11846:                  ll++;
                   11847:                  if(ll<=jj){
                   11848:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11849:                    if(ll<jj){
                   11850:                      if(itimes==1){
                   11851:                        if(mle>=1)
                   11852:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11853:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11854:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11855:                      }else{
                   11856:                        if(mle>=1)
                   11857:                          printf(" %.5e",matcov[jj][ll]); 
                   11858:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11859:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11860:                      }
                   11861:                    }else{
                   11862:                      if(itimes==1){
                   11863:                        if(mle>=1)
                   11864:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11865:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11866:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11867:                      }else{
                   11868:                        if(mle>=1)
                   11869:                          printf(" %.7e",matcov[jj][ll]); 
                   11870:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11871:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11872:                      }
                   11873:                    }
                   11874:                  }
                   11875:                } /* end lk */
                   11876:              } /* end lj */
                   11877:            } /* end li */
                   11878:            if(mle>=1)
                   11879:              printf("\n");
                   11880:            fprintf(ficlog,"\n");
                   11881:            fprintf(ficres,"\n");
                   11882:            numlinepar++;
                   11883:          } /* end k*/
                   11884:        } /*end j */
1.126     brouard  11885:       } /* end i */
                   11886:     } /* end itimes */
                   11887:     
                   11888:     fflush(ficlog);
                   11889:     fflush(ficres);
1.225     brouard  11890:     while(fgets(line, MAXLINE, ficpar)) {
                   11891:       /* If line starts with a # it is a comment */
                   11892:       if (line[0] == '#') {
                   11893:        numlinepar++;
                   11894:        fputs(line,stdout);
                   11895:        fputs(line,ficparo);
                   11896:        fputs(line,ficlog);
                   11897:        continue;
                   11898:       }else
                   11899:        break;
                   11900:     }
                   11901:     
1.209     brouard  11902:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11903:     /*   ungetc(c,ficpar); */
                   11904:     /*   fgets(line, MAXLINE, ficpar); */
                   11905:     /*   fputs(line,stdout); */
                   11906:     /*   fputs(line,ficparo); */
                   11907:     /* } */
                   11908:     /* ungetc(c,ficpar); */
1.126     brouard  11909:     
                   11910:     estepm=0;
1.209     brouard  11911:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11912:       
                   11913:       if (num_filled != 6) {
                   11914:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11915:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11916:        goto end;
                   11917:       }
                   11918:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11919:     }
                   11920:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11921:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11922:     
1.209     brouard  11923:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11924:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11925:     if (fage <= 2) {
                   11926:       bage = ageminpar;
                   11927:       fage = agemaxpar;
                   11928:     }
                   11929:     
                   11930:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11931:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11932:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11933:                
1.186     brouard  11934:     /* Other stuffs, more or less useful */    
1.254     brouard  11935:     while(fgets(line, MAXLINE, ficpar)) {
                   11936:       /* If line starts with a # it is a comment */
                   11937:       if (line[0] == '#') {
                   11938:        numlinepar++;
                   11939:        fputs(line,stdout);
                   11940:        fputs(line,ficparo);
                   11941:        fputs(line,ficlog);
                   11942:        continue;
                   11943:       }else
                   11944:        break;
                   11945:     }
                   11946: 
                   11947:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11948:       
                   11949:       if (num_filled != 7) {
                   11950:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11951:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11952:        goto end;
                   11953:       }
                   11954:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11955:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11956:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11957:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11958:     }
1.254     brouard  11959: 
                   11960:     while(fgets(line, MAXLINE, ficpar)) {
                   11961:       /* If line starts with a # it is a comment */
                   11962:       if (line[0] == '#') {
                   11963:        numlinepar++;
                   11964:        fputs(line,stdout);
                   11965:        fputs(line,ficparo);
                   11966:        fputs(line,ficlog);
                   11967:        continue;
                   11968:       }else
                   11969:        break;
1.126     brouard  11970:     }
                   11971:     
                   11972:     
                   11973:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11974:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11975:     
1.254     brouard  11976:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11977:       if (num_filled != 1) {
                   11978:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11979:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11980:        goto end;
                   11981:       }
                   11982:       printf("pop_based=%d\n",popbased);
                   11983:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11984:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11985:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11986:     }
                   11987:      
1.258     brouard  11988:     /* Results */
                   11989:     nresult=0;
                   11990:     do{
                   11991:       if(!fgets(line, MAXLINE, ficpar)){
                   11992:        endishere=1;
                   11993:        parameterline=14;
                   11994:       }else if (line[0] == '#') {
                   11995:        /* If line starts with a # it is a comment */
1.254     brouard  11996:        numlinepar++;
                   11997:        fputs(line,stdout);
                   11998:        fputs(line,ficparo);
                   11999:        fputs(line,ficlog);
                   12000:        continue;
1.258     brouard  12001:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12002:        parameterline=11;
                   12003:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12004:        parameterline=12;
                   12005:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12006:        parameterline=13;
                   12007:       else{
                   12008:        parameterline=14;
1.254     brouard  12009:       }
1.258     brouard  12010:       switch (parameterline){ 
                   12011:       case 11:
                   12012:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12013:          if (num_filled != 8) {
                   12014:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12015:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12016:            goto end;
                   12017:          }
                   12018:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12019:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12020:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12021:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12022:          /* day and month of proj2 are not used but only year anproj2.*/
                   12023:        }
1.254     brouard  12024:        break;
1.258     brouard  12025:       case 12:
                   12026:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12027:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12028:          if (num_filled != 8) {
1.262     brouard  12029:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12030:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12031:            goto end;
                   12032:          }
                   12033:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12034:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12035:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12036:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12037:          /* day and month of proj2 are not used but only year anproj2.*/
                   12038:        }
1.230     brouard  12039:        break;
1.258     brouard  12040:       case 13:
                   12041:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12042:          if (num_filled == 0){
                   12043:            resultline[0]='\0';
                   12044:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12045:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12046:            break;
                   12047:          } else if (num_filled != 1){
                   12048:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12049:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12050:          }
                   12051:          nresult++; /* Sum of resultlines */
                   12052:          printf("Result %d: result=%s\n",nresult, resultline);
                   12053:          if(nresult > MAXRESULTLINES){
                   12054:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12055:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12056:            goto end;
                   12057:          }
                   12058:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12059:          fprintf(ficparo,"result: %s\n",resultline);
                   12060:          fprintf(ficres,"result: %s\n",resultline);
                   12061:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12062:          break;
1.258     brouard  12063:        case 14: 
1.259     brouard  12064:          if(ncovmodel >2 && nresult==0 ){
                   12065:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12066:            goto end;
                   12067:          }
1.259     brouard  12068:          break;
1.258     brouard  12069:        default:
                   12070:          nresult=1;
                   12071:          decoderesult(".",nresult ); /* No covariate */
                   12072:        }
                   12073:       } /* End switch parameterline */
                   12074:     }while(endishere==0); /* End do */
1.126     brouard  12075:     
1.230     brouard  12076:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12077:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12078:     
                   12079:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12080:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12081:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12082: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12083: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12084:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12085: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12086: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12087:     }else{
1.270     brouard  12088:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12089:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12090:     }
                   12091:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12092:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  12093:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  12094:                
1.225     brouard  12095:     /*------------ free_vector  -------------*/
                   12096:     /*  chdir(path); */
1.220     brouard  12097:                
1.215     brouard  12098:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12099:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12100:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12101:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12102:     free_lvector(num,1,n);
                   12103:     free_vector(agedc,1,n);
                   12104:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12105:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12106:     fclose(ficparo);
                   12107:     fclose(ficres);
1.220     brouard  12108:                
                   12109:                
1.186     brouard  12110:     /* Other results (useful)*/
1.220     brouard  12111:                
                   12112:                
1.126     brouard  12113:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12114:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12115:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12116:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12117:     fclose(ficrespl);
                   12118: 
                   12119:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12120:     /*#include "hpijx.h"*/
                   12121:     hPijx(p, bage, fage);
1.145     brouard  12122:     fclose(ficrespij);
1.227     brouard  12123:     
1.220     brouard  12124:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12125:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12126:     k=1;
1.126     brouard  12127:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12128:     
1.269     brouard  12129:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12130:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12131:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12132:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12133:        for(k=1;k<=ncovcombmax;k++)
                   12134:          probs[i][j][k]=0.;
1.269     brouard  12135:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12136:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12137:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12138:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12139:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12140:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12141:          for(k=1;k<=ncovcombmax;k++)
                   12142:            mobaverages[i][j][k]=0.;
1.219     brouard  12143:       mobaverage=mobaverages;
                   12144:       if (mobilav!=0) {
1.235     brouard  12145:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12146:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12147:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12148:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12149:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12150:        }
1.269     brouard  12151:       } else if (mobilavproj !=0) {
1.235     brouard  12152:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12153:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12154:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12155:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12156:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12157:        }
1.269     brouard  12158:       }else{
                   12159:        printf("Internal error moving average\n");
                   12160:        fflush(stdout);
                   12161:        exit(1);
1.219     brouard  12162:       }
                   12163:     }/* end if moving average */
1.227     brouard  12164:     
1.126     brouard  12165:     /*---------- Forecasting ------------------*/
                   12166:     if(prevfcast==1){
                   12167:       /*    if(stepm ==1){*/
1.269     brouard  12168:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12169:     }
1.269     brouard  12170: 
                   12171:     /* Backcasting */
1.217     brouard  12172:     if(backcast==1){
1.219     brouard  12173:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12174:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12175:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12176: 
                   12177:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12178: 
                   12179:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12180: 
1.219     brouard  12181:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12182:       fclose(ficresplb);
                   12183: 
1.222     brouard  12184:       hBijx(p, bage, fage, mobaverage);
                   12185:       fclose(ficrespijb);
1.219     brouard  12186: 
1.269     brouard  12187:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12188:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12189:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12190: 
                   12191:       
1.269     brouard  12192:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12193:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12194:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12195:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12196:     }    /* end  Backcasting */
1.268     brouard  12197:  
1.186     brouard  12198:  
                   12199:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12200: 
1.215     brouard  12201:     free_ivector(wav,1,imx);
                   12202:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12203:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12204:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12205:                
                   12206:                
1.127     brouard  12207:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12208:                
1.201     brouard  12209:     strcpy(filerese,"E_");
                   12210:     strcat(filerese,fileresu);
1.126     brouard  12211:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12212:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12213:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12214:     }
1.208     brouard  12215:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12216:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12217: 
                   12218:     pstamp(ficreseij);
1.219     brouard  12219:                
1.235     brouard  12220:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12221:     if (cptcovn < 1){i1=1;}
                   12222:     
                   12223:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12224:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12225:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12226:        continue;
1.219     brouard  12227:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12228:       printf("\n#****** ");
1.225     brouard  12229:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12230:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12231:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12232:       }
                   12233:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12234:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12235:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12236:       }
                   12237:       fprintf(ficreseij,"******\n");
1.235     brouard  12238:       printf("******\n");
1.219     brouard  12239:       
                   12240:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12241:       oldm=oldms;savm=savms;
1.235     brouard  12242:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12243:       
1.219     brouard  12244:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12245:     }
                   12246:     fclose(ficreseij);
1.208     brouard  12247:     printf("done evsij\n");fflush(stdout);
                   12248:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12249: 
1.218     brouard  12250:                
1.227     brouard  12251:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12252:                
1.201     brouard  12253:     strcpy(filerest,"T_");
                   12254:     strcat(filerest,fileresu);
1.127     brouard  12255:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12256:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12257:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12258:     }
1.208     brouard  12259:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12260:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12261:     strcpy(fileresstde,"STDE_");
                   12262:     strcat(fileresstde,fileresu);
1.126     brouard  12263:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12264:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12265:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12266:     }
1.227     brouard  12267:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12268:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12269: 
1.201     brouard  12270:     strcpy(filerescve,"CVE_");
                   12271:     strcat(filerescve,fileresu);
1.126     brouard  12272:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12273:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12274:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12275:     }
1.227     brouard  12276:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12277:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12278: 
1.201     brouard  12279:     strcpy(fileresv,"V_");
                   12280:     strcat(fileresv,fileresu);
1.126     brouard  12281:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12282:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12283:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12284:     }
1.227     brouard  12285:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12286:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12287: 
1.235     brouard  12288:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12289:     if (cptcovn < 1){i1=1;}
                   12290:     
                   12291:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12292:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12293:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12294:        continue;
1.242     brouard  12295:       printf("\n#****** Result for:");
                   12296:       fprintf(ficrest,"\n#****** Result for:");
                   12297:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12298:       for(j=1;j<=cptcoveff;j++){ 
                   12299:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12300:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12301:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12302:       }
1.235     brouard  12303:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12304:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12305:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12306:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12307:       }        
1.208     brouard  12308:       fprintf(ficrest,"******\n");
1.227     brouard  12309:       fprintf(ficlog,"******\n");
                   12310:       printf("******\n");
1.208     brouard  12311:       
                   12312:       fprintf(ficresstdeij,"\n#****** ");
                   12313:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12314:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12315:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12316:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12317:       }
1.235     brouard  12318:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12319:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12320:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12321:       }        
1.208     brouard  12322:       fprintf(ficresstdeij,"******\n");
                   12323:       fprintf(ficrescveij,"******\n");
                   12324:       
                   12325:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12326:       /* pstamp(ficresvij); */
1.225     brouard  12327:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12328:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12329:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12330:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12331:       }        
1.208     brouard  12332:       fprintf(ficresvij,"******\n");
                   12333:       
                   12334:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12335:       oldm=oldms;savm=savms;
1.235     brouard  12336:       printf(" cvevsij ");
                   12337:       fprintf(ficlog, " cvevsij ");
                   12338:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12339:       printf(" end cvevsij \n ");
                   12340:       fprintf(ficlog, " end cvevsij \n ");
                   12341:       
                   12342:       /*
                   12343:        */
                   12344:       /* goto endfree; */
                   12345:       
                   12346:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12347:       pstamp(ficrest);
                   12348:       
1.269     brouard  12349:       epj=vector(1,nlstate+1);
1.208     brouard  12350:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12351:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12352:        cptcod= 0; /* To be deleted */
                   12353:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12354:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12355:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12356:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12357:        if(vpopbased==1)
                   12358:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12359:        else
                   12360:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12361:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12362:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12363:        fprintf(ficrest,"\n");
                   12364:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12365:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12366:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12367:        for(age=bage; age <=fage ;age++){
1.235     brouard  12368:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12369:          if (vpopbased==1) {
                   12370:            if(mobilav ==0){
                   12371:              for(i=1; i<=nlstate;i++)
                   12372:                prlim[i][i]=probs[(int)age][i][k];
                   12373:            }else{ /* mobilav */ 
                   12374:              for(i=1; i<=nlstate;i++)
                   12375:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12376:            }
                   12377:          }
1.219     brouard  12378:          
1.227     brouard  12379:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12380:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12381:          /* printf(" age %4.0f ",age); */
                   12382:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12383:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12384:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12385:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12386:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12387:            }
                   12388:            epj[nlstate+1] +=epj[j];
                   12389:          }
                   12390:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12391:          
1.227     brouard  12392:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12393:            for(j=1;j <=nlstate;j++)
                   12394:              vepp += vareij[i][j][(int)age];
                   12395:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12396:          for(j=1;j <=nlstate;j++){
                   12397:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12398:          }
                   12399:          fprintf(ficrest,"\n");
                   12400:        }
1.208     brouard  12401:       } /* End vpopbased */
1.269     brouard  12402:       free_vector(epj,1,nlstate+1);
1.208     brouard  12403:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12404:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12405:       printf("done selection\n");fflush(stdout);
                   12406:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12407:       
1.235     brouard  12408:     } /* End k selection */
1.227     brouard  12409: 
                   12410:     printf("done State-specific expectancies\n");fflush(stdout);
                   12411:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12412: 
1.269     brouard  12413:     /* variance-covariance of period prevalence*/
                   12414:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12415: 
1.227     brouard  12416:     
                   12417:     free_vector(weight,1,n);
                   12418:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12419:     free_imatrix(s,1,maxwav+1,1,n);
                   12420:     free_matrix(anint,1,maxwav,1,n); 
                   12421:     free_matrix(mint,1,maxwav,1,n);
                   12422:     free_ivector(cod,1,n);
                   12423:     free_ivector(tab,1,NCOVMAX);
                   12424:     fclose(ficresstdeij);
                   12425:     fclose(ficrescveij);
                   12426:     fclose(ficresvij);
                   12427:     fclose(ficrest);
                   12428:     fclose(ficpar);
                   12429:     
                   12430:     
1.126     brouard  12431:     /*---------- End : free ----------------*/
1.219     brouard  12432:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12433:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12434:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12435:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12436:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12437:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12438:   /* endfree:*/
                   12439:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12440:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12441:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12442:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12443:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12444:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12445:   free_matrix(covar,0,NCOVMAX,1,n);
                   12446:   free_matrix(matcov,1,npar,1,npar);
                   12447:   free_matrix(hess,1,npar,1,npar);
                   12448:   /*free_vector(delti,1,npar);*/
                   12449:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12450:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12451:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12452:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12453:   
                   12454:   free_ivector(ncodemax,1,NCOVMAX);
                   12455:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12456:   free_ivector(Dummy,-1,NCOVMAX);
                   12457:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12458:   free_ivector(DummyV,1,NCOVMAX);
                   12459:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12460:   free_ivector(Typevar,-1,NCOVMAX);
                   12461:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12462:   free_ivector(TvarsQ,1,NCOVMAX);
                   12463:   free_ivector(TvarsQind,1,NCOVMAX);
                   12464:   free_ivector(TvarsD,1,NCOVMAX);
                   12465:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12466:   free_ivector(TvarFD,1,NCOVMAX);
                   12467:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12468:   free_ivector(TvarF,1,NCOVMAX);
                   12469:   free_ivector(TvarFind,1,NCOVMAX);
                   12470:   free_ivector(TvarV,1,NCOVMAX);
                   12471:   free_ivector(TvarVind,1,NCOVMAX);
                   12472:   free_ivector(TvarA,1,NCOVMAX);
                   12473:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12474:   free_ivector(TvarFQ,1,NCOVMAX);
                   12475:   free_ivector(TvarFQind,1,NCOVMAX);
                   12476:   free_ivector(TvarVD,1,NCOVMAX);
                   12477:   free_ivector(TvarVDind,1,NCOVMAX);
                   12478:   free_ivector(TvarVQ,1,NCOVMAX);
                   12479:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12480:   free_ivector(Tvarsel,1,NCOVMAX);
                   12481:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12482:   free_ivector(Tposprod,1,NCOVMAX);
                   12483:   free_ivector(Tprod,1,NCOVMAX);
                   12484:   free_ivector(Tvaraff,1,NCOVMAX);
                   12485:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12486:   free_ivector(Tage,1,NCOVMAX);
                   12487:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12488:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12489:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12490:   
                   12491:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12492:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12493:   fflush(fichtm);
                   12494:   fflush(ficgp);
                   12495:   
1.227     brouard  12496:   
1.126     brouard  12497:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12498:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12499:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12500:   }else{
                   12501:     printf("End of Imach\n");
                   12502:     fprintf(ficlog,"End of Imach\n");
                   12503:   }
                   12504:   printf("See log file on %s\n",filelog);
                   12505:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12506:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12507:   rend_time = time(NULL);  
                   12508:   end_time = *localtime(&rend_time);
                   12509:   /* tml = *localtime(&end_time.tm_sec); */
                   12510:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12511:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12512:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12513:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12514:   
1.157     brouard  12515:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12516:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12517:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12518:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12519: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12520:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12521:   fclose(fichtm);
                   12522:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12523:   fclose(fichtmcov);
                   12524:   fclose(ficgp);
                   12525:   fclose(ficlog);
                   12526:   /*------ End -----------*/
1.227     brouard  12527:   
                   12528:   
                   12529:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12530: #ifdef WIN32
1.227     brouard  12531:   if (_chdir(pathcd) != 0)
                   12532:     printf("Can't move to directory %s!\n",path);
                   12533:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12534: #else
1.227     brouard  12535:     if(chdir(pathcd) != 0)
                   12536:       printf("Can't move to directory %s!\n", path);
                   12537:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12538: #endif 
1.126     brouard  12539:     printf("Current directory %s!\n",pathcd);
                   12540:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12541:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12542: #ifdef _WIN32
1.126     brouard  12543:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12544: #endif
                   12545:   if(!stat(plotcmd,&info)){
1.158     brouard  12546:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12547:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12548:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12549:     }else
                   12550:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12551: #ifdef __unix
1.126     brouard  12552:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12553:     if(!stat(plotcmd,&info)){
1.158     brouard  12554:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12555:     }else
                   12556:       strcpy(pplotcmd,plotcmd);
                   12557: #endif
                   12558:   }else
                   12559:     strcpy(pplotcmd,plotcmd);
                   12560:   
                   12561:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12562:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12563:   
1.126     brouard  12564:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12565:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12566:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12567:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12568:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12569:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12570:   }
1.158     brouard  12571:   printf(" Successful, please wait...");
1.126     brouard  12572:   while (z[0] != 'q') {
                   12573:     /* chdir(path); */
1.154     brouard  12574:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12575:     scanf("%s",z);
                   12576: /*     if (z[0] == 'c') system("./imach"); */
                   12577:     if (z[0] == 'e') {
1.158     brouard  12578: #ifdef __APPLE__
1.152     brouard  12579:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12580: #elif __linux
                   12581:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12582: #else
1.152     brouard  12583:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12584: #endif
                   12585:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12586:       system(pplotcmd);
1.126     brouard  12587:     }
                   12588:     else if (z[0] == 'g') system(plotcmd);
                   12589:     else if (z[0] == 'q') exit(0);
                   12590:   }
1.227     brouard  12591: end:
1.126     brouard  12592:   while (z[0] != 'q') {
1.195     brouard  12593:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12594:     scanf("%s",z);
                   12595:   }
                   12596: }

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