Annotation of imach/src/imach.c, revision 1.274

1.274   ! brouard     1: /* $Id: imach.c,v 1.273 2017/06/27 11:06:02 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.274   ! brouard     4:   Revision 1.273  2017/06/27 11:06:02  brouard
        !             5:   Summary: More documentation on projections
        !             6: 
1.273     brouard     7:   Revision 1.272  2017/06/27 10:22:40  brouard
                      8:   Summary: Color of backprojection changed from 6 to 5(yellow)
                      9: 
1.272     brouard    10:   Revision 1.271  2017/06/27 10:17:50  brouard
                     11:   Summary: Some bug with rint
                     12: 
1.271     brouard    13:   Revision 1.270  2017/05/24 05:45:29  brouard
                     14:   *** empty log message ***
                     15: 
1.270     brouard    16:   Revision 1.269  2017/05/23 08:39:25  brouard
                     17:   Summary: Code into subroutine, cleanings
                     18: 
1.269     brouard    19:   Revision 1.268  2017/05/18 20:09:32  brouard
                     20:   Summary: backprojection and confidence intervals of backprevalence
                     21: 
1.268     brouard    22:   Revision 1.267  2017/05/13 10:25:05  brouard
                     23:   Summary: temporary save for backprojection
                     24: 
1.267     brouard    25:   Revision 1.266  2017/05/13 07:26:12  brouard
                     26:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     27: 
1.266     brouard    28:   Revision 1.265  2017/04/26 16:22:11  brouard
                     29:   Summary: imach 0.99r13 Some bugs fixed
                     30: 
1.265     brouard    31:   Revision 1.264  2017/04/26 06:01:29  brouard
                     32:   Summary: Labels in graphs
                     33: 
1.264     brouard    34:   Revision 1.263  2017/04/24 15:23:15  brouard
                     35:   Summary: to save
                     36: 
1.263     brouard    37:   Revision 1.262  2017/04/18 16:48:12  brouard
                     38:   *** empty log message ***
                     39: 
1.262     brouard    40:   Revision 1.261  2017/04/05 10:14:09  brouard
                     41:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     42: 
1.261     brouard    43:   Revision 1.260  2017/04/04 17:46:59  brouard
                     44:   Summary: Gnuplot indexations fixed (humm)
                     45: 
1.260     brouard    46:   Revision 1.259  2017/04/04 13:01:16  brouard
                     47:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     48: 
1.259     brouard    49:   Revision 1.258  2017/04/03 10:17:47  brouard
                     50:   Summary: Version 0.99r12
                     51: 
                     52:   Some cleanings, conformed with updated documentation.
                     53: 
1.258     brouard    54:   Revision 1.257  2017/03/29 16:53:30  brouard
                     55:   Summary: Temp
                     56: 
1.257     brouard    57:   Revision 1.256  2017/03/27 05:50:23  brouard
                     58:   Summary: Temporary
                     59: 
1.256     brouard    60:   Revision 1.255  2017/03/08 16:02:28  brouard
                     61:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     62: 
1.255     brouard    63:   Revision 1.254  2017/03/08 07:13:00  brouard
                     64:   Summary: Fixing data parameter line
                     65: 
1.254     brouard    66:   Revision 1.253  2016/12/15 11:59:41  brouard
                     67:   Summary: 0.99 in progress
                     68: 
1.253     brouard    69:   Revision 1.252  2016/09/15 21:15:37  brouard
                     70:   *** empty log message ***
                     71: 
1.252     brouard    72:   Revision 1.251  2016/09/15 15:01:13  brouard
                     73:   Summary: not working
                     74: 
1.251     brouard    75:   Revision 1.250  2016/09/08 16:07:27  brouard
                     76:   Summary: continue
                     77: 
1.250     brouard    78:   Revision 1.249  2016/09/07 17:14:18  brouard
                     79:   Summary: Starting values from frequencies
                     80: 
1.249     brouard    81:   Revision 1.248  2016/09/07 14:10:18  brouard
                     82:   *** empty log message ***
                     83: 
1.248     brouard    84:   Revision 1.247  2016/09/02 11:11:21  brouard
                     85:   *** empty log message ***
                     86: 
1.247     brouard    87:   Revision 1.246  2016/09/02 08:49:22  brouard
                     88:   *** empty log message ***
                     89: 
1.246     brouard    90:   Revision 1.245  2016/09/02 07:25:01  brouard
                     91:   *** empty log message ***
                     92: 
1.245     brouard    93:   Revision 1.244  2016/09/02 07:17:34  brouard
                     94:   *** empty log message ***
                     95: 
1.244     brouard    96:   Revision 1.243  2016/09/02 06:45:35  brouard
                     97:   *** empty log message ***
                     98: 
1.243     brouard    99:   Revision 1.242  2016/08/30 15:01:20  brouard
                    100:   Summary: Fixing a lots
                    101: 
1.242     brouard   102:   Revision 1.241  2016/08/29 17:17:25  brouard
                    103:   Summary: gnuplot problem in Back projection to fix
                    104: 
1.241     brouard   105:   Revision 1.240  2016/08/29 07:53:18  brouard
                    106:   Summary: Better
                    107: 
1.240     brouard   108:   Revision 1.239  2016/08/26 15:51:03  brouard
                    109:   Summary: Improvement in Powell output in order to copy and paste
                    110: 
                    111:   Author:
                    112: 
1.239     brouard   113:   Revision 1.238  2016/08/26 14:23:35  brouard
                    114:   Summary: Starting tests of 0.99
                    115: 
1.238     brouard   116:   Revision 1.237  2016/08/26 09:20:19  brouard
                    117:   Summary: to valgrind
                    118: 
1.237     brouard   119:   Revision 1.236  2016/08/25 10:50:18  brouard
                    120:   *** empty log message ***
                    121: 
1.236     brouard   122:   Revision 1.235  2016/08/25 06:59:23  brouard
                    123:   *** empty log message ***
                    124: 
1.235     brouard   125:   Revision 1.234  2016/08/23 16:51:20  brouard
                    126:   *** empty log message ***
                    127: 
1.234     brouard   128:   Revision 1.233  2016/08/23 07:40:50  brouard
                    129:   Summary: not working
                    130: 
1.233     brouard   131:   Revision 1.232  2016/08/22 14:20:21  brouard
                    132:   Summary: not working
                    133: 
1.232     brouard   134:   Revision 1.231  2016/08/22 07:17:15  brouard
                    135:   Summary: not working
                    136: 
1.231     brouard   137:   Revision 1.230  2016/08/22 06:55:53  brouard
                    138:   Summary: Not working
                    139: 
1.230     brouard   140:   Revision 1.229  2016/07/23 09:45:53  brouard
                    141:   Summary: Completing for func too
                    142: 
1.229     brouard   143:   Revision 1.228  2016/07/22 17:45:30  brouard
                    144:   Summary: Fixing some arrays, still debugging
                    145: 
1.227     brouard   146:   Revision 1.226  2016/07/12 18:42:34  brouard
                    147:   Summary: temp
                    148: 
1.226     brouard   149:   Revision 1.225  2016/07/12 08:40:03  brouard
                    150:   Summary: saving but not running
                    151: 
1.225     brouard   152:   Revision 1.224  2016/07/01 13:16:01  brouard
                    153:   Summary: Fixes
                    154: 
1.224     brouard   155:   Revision 1.223  2016/02/19 09:23:35  brouard
                    156:   Summary: temporary
                    157: 
1.223     brouard   158:   Revision 1.222  2016/02/17 08:14:50  brouard
                    159:   Summary: Probably last 0.98 stable version 0.98r6
                    160: 
1.222     brouard   161:   Revision 1.221  2016/02/15 23:35:36  brouard
                    162:   Summary: minor bug
                    163: 
1.220     brouard   164:   Revision 1.219  2016/02/15 00:48:12  brouard
                    165:   *** empty log message ***
                    166: 
1.219     brouard   167:   Revision 1.218  2016/02/12 11:29:23  brouard
                    168:   Summary: 0.99 Back projections
                    169: 
1.218     brouard   170:   Revision 1.217  2015/12/23 17:18:31  brouard
                    171:   Summary: Experimental backcast
                    172: 
1.217     brouard   173:   Revision 1.216  2015/12/18 17:32:11  brouard
                    174:   Summary: 0.98r4 Warning and status=-2
                    175: 
                    176:   Version 0.98r4 is now:
                    177:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    178:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    179:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    180: 
1.216     brouard   181:   Revision 1.215  2015/12/16 08:52:24  brouard
                    182:   Summary: 0.98r4 working
                    183: 
1.215     brouard   184:   Revision 1.214  2015/12/16 06:57:54  brouard
                    185:   Summary: temporary not working
                    186: 
1.214     brouard   187:   Revision 1.213  2015/12/11 18:22:17  brouard
                    188:   Summary: 0.98r4
                    189: 
1.213     brouard   190:   Revision 1.212  2015/11/21 12:47:24  brouard
                    191:   Summary: minor typo
                    192: 
1.212     brouard   193:   Revision 1.211  2015/11/21 12:41:11  brouard
                    194:   Summary: 0.98r3 with some graph of projected cross-sectional
                    195: 
                    196:   Author: Nicolas Brouard
                    197: 
1.211     brouard   198:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   199:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   200:   Summary: Adding ftolpl parameter
                    201:   Author: N Brouard
                    202: 
                    203:   We had difficulties to get smoothed confidence intervals. It was due
                    204:   to the period prevalence which wasn't computed accurately. The inner
                    205:   parameter ftolpl is now an outer parameter of the .imach parameter
                    206:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    207:   computation are long.
                    208: 
1.209     brouard   209:   Revision 1.208  2015/11/17 14:31:57  brouard
                    210:   Summary: temporary
                    211: 
1.208     brouard   212:   Revision 1.207  2015/10/27 17:36:57  brouard
                    213:   *** empty log message ***
                    214: 
1.207     brouard   215:   Revision 1.206  2015/10/24 07:14:11  brouard
                    216:   *** empty log message ***
                    217: 
1.206     brouard   218:   Revision 1.205  2015/10/23 15:50:53  brouard
                    219:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    220: 
1.205     brouard   221:   Revision 1.204  2015/10/01 16:20:26  brouard
                    222:   Summary: Some new graphs of contribution to likelihood
                    223: 
1.204     brouard   224:   Revision 1.203  2015/09/30 17:45:14  brouard
                    225:   Summary: looking at better estimation of the hessian
                    226: 
                    227:   Also a better criteria for convergence to the period prevalence And
                    228:   therefore adding the number of years needed to converge. (The
                    229:   prevalence in any alive state shold sum to one
                    230: 
1.203     brouard   231:   Revision 1.202  2015/09/22 19:45:16  brouard
                    232:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    233: 
1.202     brouard   234:   Revision 1.201  2015/09/15 17:34:58  brouard
                    235:   Summary: 0.98r0
                    236: 
                    237:   - Some new graphs like suvival functions
                    238:   - Some bugs fixed like model=1+age+V2.
                    239: 
1.201     brouard   240:   Revision 1.200  2015/09/09 16:53:55  brouard
                    241:   Summary: Big bug thanks to Flavia
                    242: 
                    243:   Even model=1+age+V2. did not work anymore
                    244: 
1.200     brouard   245:   Revision 1.199  2015/09/07 14:09:23  brouard
                    246:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    247: 
1.199     brouard   248:   Revision 1.198  2015/09/03 07:14:39  brouard
                    249:   Summary: 0.98q5 Flavia
                    250: 
1.198     brouard   251:   Revision 1.197  2015/09/01 18:24:39  brouard
                    252:   *** empty log message ***
                    253: 
1.197     brouard   254:   Revision 1.196  2015/08/18 23:17:52  brouard
                    255:   Summary: 0.98q5
                    256: 
1.196     brouard   257:   Revision 1.195  2015/08/18 16:28:39  brouard
                    258:   Summary: Adding a hack for testing purpose
                    259: 
                    260:   After reading the title, ftol and model lines, if the comment line has
                    261:   a q, starting with #q, the answer at the end of the run is quit. It
                    262:   permits to run test files in batch with ctest. The former workaround was
                    263:   $ echo q | imach foo.imach
                    264: 
1.195     brouard   265:   Revision 1.194  2015/08/18 13:32:00  brouard
                    266:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    267: 
1.194     brouard   268:   Revision 1.193  2015/08/04 07:17:42  brouard
                    269:   Summary: 0.98q4
                    270: 
1.193     brouard   271:   Revision 1.192  2015/07/16 16:49:02  brouard
                    272:   Summary: Fixing some outputs
                    273: 
1.192     brouard   274:   Revision 1.191  2015/07/14 10:00:33  brouard
                    275:   Summary: Some fixes
                    276: 
1.191     brouard   277:   Revision 1.190  2015/05/05 08:51:13  brouard
                    278:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    279: 
                    280:   Fix 1+age+.
                    281: 
1.190     brouard   282:   Revision 1.189  2015/04/30 14:45:16  brouard
                    283:   Summary: 0.98q2
                    284: 
1.189     brouard   285:   Revision 1.188  2015/04/30 08:27:53  brouard
                    286:   *** empty log message ***
                    287: 
1.188     brouard   288:   Revision 1.187  2015/04/29 09:11:15  brouard
                    289:   *** empty log message ***
                    290: 
1.187     brouard   291:   Revision 1.186  2015/04/23 12:01:52  brouard
                    292:   Summary: V1*age is working now, version 0.98q1
                    293: 
                    294:   Some codes had been disabled in order to simplify and Vn*age was
                    295:   working in the optimization phase, ie, giving correct MLE parameters,
                    296:   but, as usual, outputs were not correct and program core dumped.
                    297: 
1.186     brouard   298:   Revision 1.185  2015/03/11 13:26:42  brouard
                    299:   Summary: Inclusion of compile and links command line for Intel Compiler
                    300: 
1.185     brouard   301:   Revision 1.184  2015/03/11 11:52:39  brouard
                    302:   Summary: Back from Windows 8. Intel Compiler
                    303: 
1.184     brouard   304:   Revision 1.183  2015/03/10 20:34:32  brouard
                    305:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    306: 
                    307:   We use directest instead of original Powell test; probably no
                    308:   incidence on the results, but better justifications;
                    309:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    310:   wrong results.
                    311: 
1.183     brouard   312:   Revision 1.182  2015/02/12 08:19:57  brouard
                    313:   Summary: Trying to keep directest which seems simpler and more general
                    314:   Author: Nicolas Brouard
                    315: 
1.182     brouard   316:   Revision 1.181  2015/02/11 23:22:24  brouard
                    317:   Summary: Comments on Powell added
                    318: 
                    319:   Author:
                    320: 
1.181     brouard   321:   Revision 1.180  2015/02/11 17:33:45  brouard
                    322:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    323: 
1.180     brouard   324:   Revision 1.179  2015/01/04 09:57:06  brouard
                    325:   Summary: back to OS/X
                    326: 
1.179     brouard   327:   Revision 1.178  2015/01/04 09:35:48  brouard
                    328:   *** empty log message ***
                    329: 
1.178     brouard   330:   Revision 1.177  2015/01/03 18:40:56  brouard
                    331:   Summary: Still testing ilc32 on OSX
                    332: 
1.177     brouard   333:   Revision 1.176  2015/01/03 16:45:04  brouard
                    334:   *** empty log message ***
                    335: 
1.176     brouard   336:   Revision 1.175  2015/01/03 16:33:42  brouard
                    337:   *** empty log message ***
                    338: 
1.175     brouard   339:   Revision 1.174  2015/01/03 16:15:49  brouard
                    340:   Summary: Still in cross-compilation
                    341: 
1.174     brouard   342:   Revision 1.173  2015/01/03 12:06:26  brouard
                    343:   Summary: trying to detect cross-compilation
                    344: 
1.173     brouard   345:   Revision 1.172  2014/12/27 12:07:47  brouard
                    346:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    347: 
1.172     brouard   348:   Revision 1.171  2014/12/23 13:26:59  brouard
                    349:   Summary: Back from Visual C
                    350: 
                    351:   Still problem with utsname.h on Windows
                    352: 
1.171     brouard   353:   Revision 1.170  2014/12/23 11:17:12  brouard
                    354:   Summary: Cleaning some \%% back to %%
                    355: 
                    356:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    357: 
1.170     brouard   358:   Revision 1.169  2014/12/22 23:08:31  brouard
                    359:   Summary: 0.98p
                    360: 
                    361:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    362: 
1.169     brouard   363:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   364:   Summary: update
1.169     brouard   365: 
1.168     brouard   366:   Revision 1.167  2014/12/22 13:50:56  brouard
                    367:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    368: 
                    369:   Testing on Linux 64
                    370: 
1.167     brouard   371:   Revision 1.166  2014/12/22 11:40:47  brouard
                    372:   *** empty log message ***
                    373: 
1.166     brouard   374:   Revision 1.165  2014/12/16 11:20:36  brouard
                    375:   Summary: After compiling on Visual C
                    376: 
                    377:   * imach.c (Module): Merging 1.61 to 1.162
                    378: 
1.165     brouard   379:   Revision 1.164  2014/12/16 10:52:11  brouard
                    380:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    381: 
                    382:   * imach.c (Module): Merging 1.61 to 1.162
                    383: 
1.164     brouard   384:   Revision 1.163  2014/12/16 10:30:11  brouard
                    385:   * imach.c (Module): Merging 1.61 to 1.162
                    386: 
1.163     brouard   387:   Revision 1.162  2014/09/25 11:43:39  brouard
                    388:   Summary: temporary backup 0.99!
                    389: 
1.162     brouard   390:   Revision 1.1  2014/09/16 11:06:58  brouard
                    391:   Summary: With some code (wrong) for nlopt
                    392: 
                    393:   Author:
                    394: 
                    395:   Revision 1.161  2014/09/15 20:41:41  brouard
                    396:   Summary: Problem with macro SQR on Intel compiler
                    397: 
1.161     brouard   398:   Revision 1.160  2014/09/02 09:24:05  brouard
                    399:   *** empty log message ***
                    400: 
1.160     brouard   401:   Revision 1.159  2014/09/01 10:34:10  brouard
                    402:   Summary: WIN32
                    403:   Author: Brouard
                    404: 
1.159     brouard   405:   Revision 1.158  2014/08/27 17:11:51  brouard
                    406:   *** empty log message ***
                    407: 
1.158     brouard   408:   Revision 1.157  2014/08/27 16:26:55  brouard
                    409:   Summary: Preparing windows Visual studio version
                    410:   Author: Brouard
                    411: 
                    412:   In order to compile on Visual studio, time.h is now correct and time_t
                    413:   and tm struct should be used. difftime should be used but sometimes I
                    414:   just make the differences in raw time format (time(&now).
                    415:   Trying to suppress #ifdef LINUX
                    416:   Add xdg-open for __linux in order to open default browser.
                    417: 
1.157     brouard   418:   Revision 1.156  2014/08/25 20:10:10  brouard
                    419:   *** empty log message ***
                    420: 
1.156     brouard   421:   Revision 1.155  2014/08/25 18:32:34  brouard
                    422:   Summary: New compile, minor changes
                    423:   Author: Brouard
                    424: 
1.155     brouard   425:   Revision 1.154  2014/06/20 17:32:08  brouard
                    426:   Summary: Outputs now all graphs of convergence to period prevalence
                    427: 
1.154     brouard   428:   Revision 1.153  2014/06/20 16:45:46  brouard
                    429:   Summary: If 3 live state, convergence to period prevalence on same graph
                    430:   Author: Brouard
                    431: 
1.153     brouard   432:   Revision 1.152  2014/06/18 17:54:09  brouard
                    433:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    434: 
1.152     brouard   435:   Revision 1.151  2014/06/18 16:43:30  brouard
                    436:   *** empty log message ***
                    437: 
1.151     brouard   438:   Revision 1.150  2014/06/18 16:42:35  brouard
                    439:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    440:   Author: brouard
                    441: 
1.150     brouard   442:   Revision 1.149  2014/06/18 15:51:14  brouard
                    443:   Summary: Some fixes in parameter files errors
                    444:   Author: Nicolas Brouard
                    445: 
1.149     brouard   446:   Revision 1.148  2014/06/17 17:38:48  brouard
                    447:   Summary: Nothing new
                    448:   Author: Brouard
                    449: 
                    450:   Just a new packaging for OS/X version 0.98nS
                    451: 
1.148     brouard   452:   Revision 1.147  2014/06/16 10:33:11  brouard
                    453:   *** empty log message ***
                    454: 
1.147     brouard   455:   Revision 1.146  2014/06/16 10:20:28  brouard
                    456:   Summary: Merge
                    457:   Author: Brouard
                    458: 
                    459:   Merge, before building revised version.
                    460: 
1.146     brouard   461:   Revision 1.145  2014/06/10 21:23:15  brouard
                    462:   Summary: Debugging with valgrind
                    463:   Author: Nicolas Brouard
                    464: 
                    465:   Lot of changes in order to output the results with some covariates
                    466:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    467:   improve the code.
                    468:   No more memory valgrind error but a lot has to be done in order to
                    469:   continue the work of splitting the code into subroutines.
                    470:   Also, decodemodel has been improved. Tricode is still not
                    471:   optimal. nbcode should be improved. Documentation has been added in
                    472:   the source code.
                    473: 
1.144     brouard   474:   Revision 1.143  2014/01/26 09:45:38  brouard
                    475:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    476: 
                    477:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    478:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    479: 
1.143     brouard   480:   Revision 1.142  2014/01/26 03:57:36  brouard
                    481:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    482: 
                    483:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    484: 
1.142     brouard   485:   Revision 1.141  2014/01/26 02:42:01  brouard
                    486:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    487: 
1.141     brouard   488:   Revision 1.140  2011/09/02 10:37:54  brouard
                    489:   Summary: times.h is ok with mingw32 now.
                    490: 
1.140     brouard   491:   Revision 1.139  2010/06/14 07:50:17  brouard
                    492:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    493:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    494: 
1.139     brouard   495:   Revision 1.138  2010/04/30 18:19:40  brouard
                    496:   *** empty log message ***
                    497: 
1.138     brouard   498:   Revision 1.137  2010/04/29 18:11:38  brouard
                    499:   (Module): Checking covariates for more complex models
                    500:   than V1+V2. A lot of change to be done. Unstable.
                    501: 
1.137     brouard   502:   Revision 1.136  2010/04/26 20:30:53  brouard
                    503:   (Module): merging some libgsl code. Fixing computation
                    504:   of likelione (using inter/intrapolation if mle = 0) in order to
                    505:   get same likelihood as if mle=1.
                    506:   Some cleaning of code and comments added.
                    507: 
1.136     brouard   508:   Revision 1.135  2009/10/29 15:33:14  brouard
                    509:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    510: 
1.135     brouard   511:   Revision 1.134  2009/10/29 13:18:53  brouard
                    512:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    513: 
1.134     brouard   514:   Revision 1.133  2009/07/06 10:21:25  brouard
                    515:   just nforces
                    516: 
1.133     brouard   517:   Revision 1.132  2009/07/06 08:22:05  brouard
                    518:   Many tings
                    519: 
1.132     brouard   520:   Revision 1.131  2009/06/20 16:22:47  brouard
                    521:   Some dimensions resccaled
                    522: 
1.131     brouard   523:   Revision 1.130  2009/05/26 06:44:34  brouard
                    524:   (Module): Max Covariate is now set to 20 instead of 8. A
                    525:   lot of cleaning with variables initialized to 0. Trying to make
                    526:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    527: 
1.130     brouard   528:   Revision 1.129  2007/08/31 13:49:27  lievre
                    529:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    530: 
1.129     lievre    531:   Revision 1.128  2006/06/30 13:02:05  brouard
                    532:   (Module): Clarifications on computing e.j
                    533: 
1.128     brouard   534:   Revision 1.127  2006/04/28 18:11:50  brouard
                    535:   (Module): Yes the sum of survivors was wrong since
                    536:   imach-114 because nhstepm was no more computed in the age
                    537:   loop. Now we define nhstepma in the age loop.
                    538:   (Module): In order to speed up (in case of numerous covariates) we
                    539:   compute health expectancies (without variances) in a first step
                    540:   and then all the health expectancies with variances or standard
                    541:   deviation (needs data from the Hessian matrices) which slows the
                    542:   computation.
                    543:   In the future we should be able to stop the program is only health
                    544:   expectancies and graph are needed without standard deviations.
                    545: 
1.127     brouard   546:   Revision 1.126  2006/04/28 17:23:28  brouard
                    547:   (Module): Yes the sum of survivors was wrong since
                    548:   imach-114 because nhstepm was no more computed in the age
                    549:   loop. Now we define nhstepma in the age loop.
                    550:   Version 0.98h
                    551: 
1.126     brouard   552:   Revision 1.125  2006/04/04 15:20:31  lievre
                    553:   Errors in calculation of health expectancies. Age was not initialized.
                    554:   Forecasting file added.
                    555: 
                    556:   Revision 1.124  2006/03/22 17:13:53  lievre
                    557:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    558:   The log-likelihood is printed in the log file
                    559: 
                    560:   Revision 1.123  2006/03/20 10:52:43  brouard
                    561:   * imach.c (Module): <title> changed, corresponds to .htm file
                    562:   name. <head> headers where missing.
                    563: 
                    564:   * imach.c (Module): Weights can have a decimal point as for
                    565:   English (a comma might work with a correct LC_NUMERIC environment,
                    566:   otherwise the weight is truncated).
                    567:   Modification of warning when the covariates values are not 0 or
                    568:   1.
                    569:   Version 0.98g
                    570: 
                    571:   Revision 1.122  2006/03/20 09:45:41  brouard
                    572:   (Module): Weights can have a decimal point as for
                    573:   English (a comma might work with a correct LC_NUMERIC environment,
                    574:   otherwise the weight is truncated).
                    575:   Modification of warning when the covariates values are not 0 or
                    576:   1.
                    577:   Version 0.98g
                    578: 
                    579:   Revision 1.121  2006/03/16 17:45:01  lievre
                    580:   * imach.c (Module): Comments concerning covariates added
                    581: 
                    582:   * imach.c (Module): refinements in the computation of lli if
                    583:   status=-2 in order to have more reliable computation if stepm is
                    584:   not 1 month. Version 0.98f
                    585: 
                    586:   Revision 1.120  2006/03/16 15:10:38  lievre
                    587:   (Module): refinements in the computation of lli if
                    588:   status=-2 in order to have more reliable computation if stepm is
                    589:   not 1 month. Version 0.98f
                    590: 
                    591:   Revision 1.119  2006/03/15 17:42:26  brouard
                    592:   (Module): Bug if status = -2, the loglikelihood was
                    593:   computed as likelihood omitting the logarithm. Version O.98e
                    594: 
                    595:   Revision 1.118  2006/03/14 18:20:07  brouard
                    596:   (Module): varevsij Comments added explaining the second
                    597:   table of variances if popbased=1 .
                    598:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    599:   (Module): Function pstamp added
                    600:   (Module): Version 0.98d
                    601: 
                    602:   Revision 1.117  2006/03/14 17:16:22  brouard
                    603:   (Module): varevsij Comments added explaining the second
                    604:   table of variances if popbased=1 .
                    605:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    606:   (Module): Function pstamp added
                    607:   (Module): Version 0.98d
                    608: 
                    609:   Revision 1.116  2006/03/06 10:29:27  brouard
                    610:   (Module): Variance-covariance wrong links and
                    611:   varian-covariance of ej. is needed (Saito).
                    612: 
                    613:   Revision 1.115  2006/02/27 12:17:45  brouard
                    614:   (Module): One freematrix added in mlikeli! 0.98c
                    615: 
                    616:   Revision 1.114  2006/02/26 12:57:58  brouard
                    617:   (Module): Some improvements in processing parameter
                    618:   filename with strsep.
                    619: 
                    620:   Revision 1.113  2006/02/24 14:20:24  brouard
                    621:   (Module): Memory leaks checks with valgrind and:
                    622:   datafile was not closed, some imatrix were not freed and on matrix
                    623:   allocation too.
                    624: 
                    625:   Revision 1.112  2006/01/30 09:55:26  brouard
                    626:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    627: 
                    628:   Revision 1.111  2006/01/25 20:38:18  brouard
                    629:   (Module): Lots of cleaning and bugs added (Gompertz)
                    630:   (Module): Comments can be added in data file. Missing date values
                    631:   can be a simple dot '.'.
                    632: 
                    633:   Revision 1.110  2006/01/25 00:51:50  brouard
                    634:   (Module): Lots of cleaning and bugs added (Gompertz)
                    635: 
                    636:   Revision 1.109  2006/01/24 19:37:15  brouard
                    637:   (Module): Comments (lines starting with a #) are allowed in data.
                    638: 
                    639:   Revision 1.108  2006/01/19 18:05:42  lievre
                    640:   Gnuplot problem appeared...
                    641:   To be fixed
                    642: 
                    643:   Revision 1.107  2006/01/19 16:20:37  brouard
                    644:   Test existence of gnuplot in imach path
                    645: 
                    646:   Revision 1.106  2006/01/19 13:24:36  brouard
                    647:   Some cleaning and links added in html output
                    648: 
                    649:   Revision 1.105  2006/01/05 20:23:19  lievre
                    650:   *** empty log message ***
                    651: 
                    652:   Revision 1.104  2005/09/30 16:11:43  lievre
                    653:   (Module): sump fixed, loop imx fixed, and simplifications.
                    654:   (Module): If the status is missing at the last wave but we know
                    655:   that the person is alive, then we can code his/her status as -2
                    656:   (instead of missing=-1 in earlier versions) and his/her
                    657:   contributions to the likelihood is 1 - Prob of dying from last
                    658:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    659:   the healthy state at last known wave). Version is 0.98
                    660: 
                    661:   Revision 1.103  2005/09/30 15:54:49  lievre
                    662:   (Module): sump fixed, loop imx fixed, and simplifications.
                    663: 
                    664:   Revision 1.102  2004/09/15 17:31:30  brouard
                    665:   Add the possibility to read data file including tab characters.
                    666: 
                    667:   Revision 1.101  2004/09/15 10:38:38  brouard
                    668:   Fix on curr_time
                    669: 
                    670:   Revision 1.100  2004/07/12 18:29:06  brouard
                    671:   Add version for Mac OS X. Just define UNIX in Makefile
                    672: 
                    673:   Revision 1.99  2004/06/05 08:57:40  brouard
                    674:   *** empty log message ***
                    675: 
                    676:   Revision 1.98  2004/05/16 15:05:56  brouard
                    677:   New version 0.97 . First attempt to estimate force of mortality
                    678:   directly from the data i.e. without the need of knowing the health
                    679:   state at each age, but using a Gompertz model: log u =a + b*age .
                    680:   This is the basic analysis of mortality and should be done before any
                    681:   other analysis, in order to test if the mortality estimated from the
                    682:   cross-longitudinal survey is different from the mortality estimated
                    683:   from other sources like vital statistic data.
                    684: 
                    685:   The same imach parameter file can be used but the option for mle should be -3.
                    686: 
1.133     brouard   687:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   688:   former routines in order to include the new code within the former code.
                    689: 
                    690:   The output is very simple: only an estimate of the intercept and of
                    691:   the slope with 95% confident intervals.
                    692: 
                    693:   Current limitations:
                    694:   A) Even if you enter covariates, i.e. with the
                    695:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    696:   B) There is no computation of Life Expectancy nor Life Table.
                    697: 
                    698:   Revision 1.97  2004/02/20 13:25:42  lievre
                    699:   Version 0.96d. Population forecasting command line is (temporarily)
                    700:   suppressed.
                    701: 
                    702:   Revision 1.96  2003/07/15 15:38:55  brouard
                    703:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    704:   rewritten within the same printf. Workaround: many printfs.
                    705: 
                    706:   Revision 1.95  2003/07/08 07:54:34  brouard
                    707:   * imach.c (Repository):
                    708:   (Repository): Using imachwizard code to output a more meaningful covariance
                    709:   matrix (cov(a12,c31) instead of numbers.
                    710: 
                    711:   Revision 1.94  2003/06/27 13:00:02  brouard
                    712:   Just cleaning
                    713: 
                    714:   Revision 1.93  2003/06/25 16:33:55  brouard
                    715:   (Module): On windows (cygwin) function asctime_r doesn't
                    716:   exist so I changed back to asctime which exists.
                    717:   (Module): Version 0.96b
                    718: 
                    719:   Revision 1.92  2003/06/25 16:30:45  brouard
                    720:   (Module): On windows (cygwin) function asctime_r doesn't
                    721:   exist so I changed back to asctime which exists.
                    722: 
                    723:   Revision 1.91  2003/06/25 15:30:29  brouard
                    724:   * imach.c (Repository): Duplicated warning errors corrected.
                    725:   (Repository): Elapsed time after each iteration is now output. It
                    726:   helps to forecast when convergence will be reached. Elapsed time
                    727:   is stamped in powell.  We created a new html file for the graphs
                    728:   concerning matrix of covariance. It has extension -cov.htm.
                    729: 
                    730:   Revision 1.90  2003/06/24 12:34:15  brouard
                    731:   (Module): Some bugs corrected for windows. Also, when
                    732:   mle=-1 a template is output in file "or"mypar.txt with the design
                    733:   of the covariance matrix to be input.
                    734: 
                    735:   Revision 1.89  2003/06/24 12:30:52  brouard
                    736:   (Module): Some bugs corrected for windows. Also, when
                    737:   mle=-1 a template is output in file "or"mypar.txt with the design
                    738:   of the covariance matrix to be input.
                    739: 
                    740:   Revision 1.88  2003/06/23 17:54:56  brouard
                    741:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    742: 
                    743:   Revision 1.87  2003/06/18 12:26:01  brouard
                    744:   Version 0.96
                    745: 
                    746:   Revision 1.86  2003/06/17 20:04:08  brouard
                    747:   (Module): Change position of html and gnuplot routines and added
                    748:   routine fileappend.
                    749: 
                    750:   Revision 1.85  2003/06/17 13:12:43  brouard
                    751:   * imach.c (Repository): Check when date of death was earlier that
                    752:   current date of interview. It may happen when the death was just
                    753:   prior to the death. In this case, dh was negative and likelihood
                    754:   was wrong (infinity). We still send an "Error" but patch by
                    755:   assuming that the date of death was just one stepm after the
                    756:   interview.
                    757:   (Repository): Because some people have very long ID (first column)
                    758:   we changed int to long in num[] and we added a new lvector for
                    759:   memory allocation. But we also truncated to 8 characters (left
                    760:   truncation)
                    761:   (Repository): No more line truncation errors.
                    762: 
                    763:   Revision 1.84  2003/06/13 21:44:43  brouard
                    764:   * imach.c (Repository): Replace "freqsummary" at a correct
                    765:   place. It differs from routine "prevalence" which may be called
                    766:   many times. Probs is memory consuming and must be used with
                    767:   parcimony.
                    768:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    769: 
                    770:   Revision 1.83  2003/06/10 13:39:11  lievre
                    771:   *** empty log message ***
                    772: 
                    773:   Revision 1.82  2003/06/05 15:57:20  brouard
                    774:   Add log in  imach.c and  fullversion number is now printed.
                    775: 
                    776: */
                    777: /*
                    778:    Interpolated Markov Chain
                    779: 
                    780:   Short summary of the programme:
                    781:   
1.227     brouard   782:   This program computes Healthy Life Expectancies or State-specific
                    783:   (if states aren't health statuses) Expectancies from
                    784:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    785: 
                    786:   -1- a first survey ("cross") where individuals from different ages
                    787:   are interviewed on their health status or degree of disability (in
                    788:   the case of a health survey which is our main interest)
                    789: 
                    790:   -2- at least a second wave of interviews ("longitudinal") which
                    791:   measure each change (if any) in individual health status.  Health
                    792:   expectancies are computed from the time spent in each health state
                    793:   according to a model. More health states you consider, more time is
                    794:   necessary to reach the Maximum Likelihood of the parameters involved
                    795:   in the model.  The simplest model is the multinomial logistic model
                    796:   where pij is the probability to be observed in state j at the second
                    797:   wave conditional to be observed in state i at the first
                    798:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    799:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    800:   have a more complex model than "constant and age", you should modify
                    801:   the program where the markup *Covariates have to be included here
                    802:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   803:   convergence.
                    804: 
                    805:   The advantage of this computer programme, compared to a simple
                    806:   multinomial logistic model, is clear when the delay between waves is not
                    807:   identical for each individual. Also, if a individual missed an
                    808:   intermediate interview, the information is lost, but taken into
                    809:   account using an interpolation or extrapolation.  
                    810: 
                    811:   hPijx is the probability to be observed in state i at age x+h
                    812:   conditional to the observed state i at age x. The delay 'h' can be
                    813:   split into an exact number (nh*stepm) of unobserved intermediate
                    814:   states. This elementary transition (by month, quarter,
                    815:   semester or year) is modelled as a multinomial logistic.  The hPx
                    816:   matrix is simply the matrix product of nh*stepm elementary matrices
                    817:   and the contribution of each individual to the likelihood is simply
                    818:   hPijx.
                    819: 
                    820:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   821:   of the life expectancies. It also computes the period (stable) prevalence.
                    822: 
                    823: Back prevalence and projections:
1.227     brouard   824: 
                    825:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    826:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    827:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    828:    mobilavproj)
                    829: 
                    830:     Computes the back prevalence limit for any combination of
                    831:     covariate values k at any age between ageminpar and agemaxpar and
                    832:     returns it in **bprlim. In the loops,
                    833: 
                    834:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    835:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    836: 
                    837:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   838:    Computes for any combination of covariates k and any age between bage and fage 
                    839:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    840:                        oldm=oldms;savm=savms;
1.227     brouard   841: 
1.267     brouard   842:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   843:      Computes the transition matrix starting at age 'age' over
                    844:      'nhstepm*hstepm*stepm' months (i.e. until
                    845:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   846:      nhstepm*hstepm matrices. 
                    847: 
                    848:      Returns p3mat[i][j][h] after calling
                    849:      p3mat[i][j][h]=matprod2(newm,
                    850:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    851:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    852:      oldm);
1.226     brouard   853: 
                    854: Important routines
                    855: 
                    856: - func (or funcone), computes logit (pij) distinguishing
                    857:   o fixed variables (single or product dummies or quantitative);
                    858:   o varying variables by:
                    859:    (1) wave (single, product dummies, quantitative), 
                    860:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    861:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    862:        % varying dummy (not done) or quantitative (not done);
                    863: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    864:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    865: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    866:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    867:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   868: 
1.226     brouard   869: 
                    870:   
1.133     brouard   871:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    872:            Institut national d'études démographiques, Paris.
1.126     brouard   873:   This software have been partly granted by Euro-REVES, a concerted action
                    874:   from the European Union.
                    875:   It is copyrighted identically to a GNU software product, ie programme and
                    876:   software can be distributed freely for non commercial use. Latest version
                    877:   can be accessed at http://euroreves.ined.fr/imach .
                    878: 
                    879:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    880:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    881:   
                    882:   **********************************************************************/
                    883: /*
                    884:   main
                    885:   read parameterfile
                    886:   read datafile
                    887:   concatwav
                    888:   freqsummary
                    889:   if (mle >= 1)
                    890:     mlikeli
                    891:   print results files
                    892:   if mle==1 
                    893:      computes hessian
                    894:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    895:       begin-prev-date,...
                    896:   open gnuplot file
                    897:   open html file
1.145     brouard   898:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    899:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    900:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    901:     freexexit2 possible for memory heap.
                    902: 
                    903:   h Pij x                         | pij_nom  ficrestpij
                    904:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    905:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    906:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    907: 
                    908:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    909:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    910:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    911:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    912:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    913: 
1.126     brouard   914:   forecasting if prevfcast==1 prevforecast call prevalence()
                    915:   health expectancies
                    916:   Variance-covariance of DFLE
                    917:   prevalence()
                    918:    movingaverage()
                    919:   varevsij() 
                    920:   if popbased==1 varevsij(,popbased)
                    921:   total life expectancies
                    922:   Variance of period (stable) prevalence
                    923:  end
                    924: */
                    925: 
1.187     brouard   926: /* #define DEBUG */
                    927: /* #define DEBUGBRENT */
1.203     brouard   928: /* #define DEBUGLINMIN */
                    929: /* #define DEBUGHESS */
                    930: #define DEBUGHESSIJ
1.224     brouard   931: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   932: #define POWELL /* Instead of NLOPT */
1.224     brouard   933: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   934: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    935: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   936: 
                    937: #include <math.h>
                    938: #include <stdio.h>
                    939: #include <stdlib.h>
                    940: #include <string.h>
1.226     brouard   941: #include <ctype.h>
1.159     brouard   942: 
                    943: #ifdef _WIN32
                    944: #include <io.h>
1.172     brouard   945: #include <windows.h>
                    946: #include <tchar.h>
1.159     brouard   947: #else
1.126     brouard   948: #include <unistd.h>
1.159     brouard   949: #endif
1.126     brouard   950: 
                    951: #include <limits.h>
                    952: #include <sys/types.h>
1.171     brouard   953: 
                    954: #if defined(__GNUC__)
                    955: #include <sys/utsname.h> /* Doesn't work on Windows */
                    956: #endif
                    957: 
1.126     brouard   958: #include <sys/stat.h>
                    959: #include <errno.h>
1.159     brouard   960: /* extern int errno; */
1.126     brouard   961: 
1.157     brouard   962: /* #ifdef LINUX */
                    963: /* #include <time.h> */
                    964: /* #include "timeval.h" */
                    965: /* #else */
                    966: /* #include <sys/time.h> */
                    967: /* #endif */
                    968: 
1.126     brouard   969: #include <time.h>
                    970: 
1.136     brouard   971: #ifdef GSL
                    972: #include <gsl/gsl_errno.h>
                    973: #include <gsl/gsl_multimin.h>
                    974: #endif
                    975: 
1.167     brouard   976: 
1.162     brouard   977: #ifdef NLOPT
                    978: #include <nlopt.h>
                    979: typedef struct {
                    980:   double (* function)(double [] );
                    981: } myfunc_data ;
                    982: #endif
                    983: 
1.126     brouard   984: /* #include <libintl.h> */
                    985: /* #define _(String) gettext (String) */
                    986: 
1.251     brouard   987: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   988: 
                    989: #define GNUPLOTPROGRAM "gnuplot"
                    990: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    991: #define FILENAMELENGTH 132
                    992: 
                    993: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    994: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    995: 
1.144     brouard   996: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    997: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   998: 
                    999: #define NINTERVMAX 8
1.144     brouard  1000: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1001: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1002: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1003: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1004: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1005: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1006: #define MAXN 20000
1.144     brouard  1007: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1008: /* #define AGESUP 130 */
                   1009: #define AGESUP 150
1.268     brouard  1010: #define AGEINF 0
1.218     brouard  1011: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1012: #define AGEBASE 40
1.194     brouard  1013: #define AGEOVERFLOW 1.e20
1.164     brouard  1014: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1015: #ifdef _WIN32
                   1016: #define DIRSEPARATOR '\\'
                   1017: #define CHARSEPARATOR "\\"
                   1018: #define ODIRSEPARATOR '/'
                   1019: #else
1.126     brouard  1020: #define DIRSEPARATOR '/'
                   1021: #define CHARSEPARATOR "/"
                   1022: #define ODIRSEPARATOR '\\'
                   1023: #endif
                   1024: 
1.274   ! brouard  1025: /* $Id: imach.c,v 1.273 2017/06/27 11:06:02 brouard Exp $ */
1.126     brouard  1026: /* $State: Exp $ */
1.196     brouard  1027: #include "version.h"
                   1028: char version[]=__IMACH_VERSION__;
1.224     brouard  1029: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.274   ! brouard  1030: char fullversion[]="$Revision: 1.273 $ $Date: 2017/06/27 11:06:02 $"; 
1.126     brouard  1031: char strstart[80];
                   1032: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1033: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1034: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1035: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1036: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1037: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1038: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1039: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1040: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1041: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1042: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1043: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1044: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1045: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1046: int nsd=0; /**< Total number of single dummy variables (output) */
                   1047: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1048: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1049: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1050: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1051: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1052: int cptcov=0; /* Working variable */
1.218     brouard  1053: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1054: int npar=NPARMAX;
                   1055: int nlstate=2; /* Number of live states */
                   1056: int ndeath=1; /* Number of dead states */
1.130     brouard  1057: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1058: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1059: int popbased=0;
                   1060: 
                   1061: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1062: int maxwav=0; /* Maxim number of waves */
                   1063: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1064: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1065: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1066:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1067: int mle=1, weightopt=0;
1.126     brouard  1068: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1069: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1070: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1071:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1072: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1073: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1074: 
1.130     brouard  1075: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1076: double **matprod2(); /* test */
1.126     brouard  1077: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1078: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1079: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1080: 
1.136     brouard  1081: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1082: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1083: FILE *ficlog, *ficrespow;
1.130     brouard  1084: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1085: double fretone; /* Only one call to likelihood */
1.130     brouard  1086: long ipmx=0; /* Number of contributions */
1.126     brouard  1087: double sw; /* Sum of weights */
                   1088: char filerespow[FILENAMELENGTH];
                   1089: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1090: FILE *ficresilk;
                   1091: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1092: FILE *ficresprobmorprev;
                   1093: FILE *fichtm, *fichtmcov; /* Html File */
                   1094: FILE *ficreseij;
                   1095: char filerese[FILENAMELENGTH];
                   1096: FILE *ficresstdeij;
                   1097: char fileresstde[FILENAMELENGTH];
                   1098: FILE *ficrescveij;
                   1099: char filerescve[FILENAMELENGTH];
                   1100: FILE  *ficresvij;
                   1101: char fileresv[FILENAMELENGTH];
1.269     brouard  1102: 
1.126     brouard  1103: char title[MAXLINE];
1.234     brouard  1104: char model[MAXLINE]; /**< The model line */
1.217     brouard  1105: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1106: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1107: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1108: char command[FILENAMELENGTH];
                   1109: int  outcmd=0;
                   1110: 
1.217     brouard  1111: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1112: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1113: char filelog[FILENAMELENGTH]; /* Log file */
                   1114: char filerest[FILENAMELENGTH];
                   1115: char fileregp[FILENAMELENGTH];
                   1116: char popfile[FILENAMELENGTH];
                   1117: 
                   1118: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1119: 
1.157     brouard  1120: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1121: /* struct timezone tzp; */
                   1122: /* extern int gettimeofday(); */
                   1123: struct tm tml, *gmtime(), *localtime();
                   1124: 
                   1125: extern time_t time();
                   1126: 
                   1127: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1128: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1129: struct tm tm;
                   1130: 
1.126     brouard  1131: char strcurr[80], strfor[80];
                   1132: 
                   1133: char *endptr;
                   1134: long lval;
                   1135: double dval;
                   1136: 
                   1137: #define NR_END 1
                   1138: #define FREE_ARG char*
                   1139: #define FTOL 1.0e-10
                   1140: 
                   1141: #define NRANSI 
1.240     brouard  1142: #define ITMAX 200
                   1143: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1144: 
                   1145: #define TOL 2.0e-4 
                   1146: 
                   1147: #define CGOLD 0.3819660 
                   1148: #define ZEPS 1.0e-10 
                   1149: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1150: 
                   1151: #define GOLD 1.618034 
                   1152: #define GLIMIT 100.0 
                   1153: #define TINY 1.0e-20 
                   1154: 
                   1155: static double maxarg1,maxarg2;
                   1156: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1157: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1158:   
                   1159: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1160: #define rint(a) floor(a+0.5)
1.166     brouard  1161: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1162: #define mytinydouble 1.0e-16
1.166     brouard  1163: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1164: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1165: /* static double dsqrarg; */
                   1166: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1167: static double sqrarg;
                   1168: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1169: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1170: int agegomp= AGEGOMP;
                   1171: 
                   1172: int imx; 
                   1173: int stepm=1;
                   1174: /* Stepm, step in month: minimum step interpolation*/
                   1175: 
                   1176: int estepm;
                   1177: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1178: 
                   1179: int m,nb;
                   1180: long *num;
1.197     brouard  1181: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1182: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1183:                   covariate for which somebody answered excluding 
                   1184:                   undefined. Usually 2: 0 and 1. */
                   1185: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1186:                             covariate for which somebody answered including 
                   1187:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1188: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1189: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1190: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1191: double *ageexmed,*agecens;
                   1192: double dateintmean=0;
                   1193: 
                   1194: double *weight;
                   1195: int **s; /* Status */
1.141     brouard  1196: double *agedc;
1.145     brouard  1197: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1198:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1199:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1200: double **coqvar; /* Fixed quantitative covariate nqv */
                   1201: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1202: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1203: double  idx; 
                   1204: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1205: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1206: /*k          1  2   3   4     5    6    7     8    9 */
                   1207: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1208: /* Tndvar[k]    1   2   3               4          5 */
                   1209: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1210: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1211: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1212: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1213: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1214: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1215: /* Tprod[i]=k           4               7            */
                   1216: /* Tage[i]=k                  5               8      */
                   1217: /* */
                   1218: /* Type                    */
                   1219: /* V         1  2  3  4  5 */
                   1220: /*           F  F  V  V  V */
                   1221: /*           D  Q  D  D  Q */
                   1222: /*                         */
                   1223: int *TvarsD;
                   1224: int *TvarsDind;
                   1225: int *TvarsQ;
                   1226: int *TvarsQind;
                   1227: 
1.235     brouard  1228: #define MAXRESULTLINES 10
                   1229: int nresult=0;
1.258     brouard  1230: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1231: int TKresult[MAXRESULTLINES];
1.237     brouard  1232: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1233: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1234: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1235: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1236: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1237: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1238: 
1.234     brouard  1239: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1240: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1241: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1242: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1243: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1244: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1245: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1246: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1247: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1248: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1249: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1250: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1251: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1252: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1253: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1254: 
1.230     brouard  1255: int *Tvarsel; /**< Selected covariates for output */
                   1256: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1257: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1258: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1259: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1260: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1261: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1262: int *Tage;
1.227     brouard  1263: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1264: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1265: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1266: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1267: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1268: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1269: int **Tvard;
                   1270: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1271: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1272: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1273:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1274:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1275: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1276: double *lsurv, *lpop, *tpop;
                   1277: 
1.231     brouard  1278: #define FD 1; /* Fixed dummy covariate */
                   1279: #define FQ 2; /* Fixed quantitative covariate */
                   1280: #define FP 3; /* Fixed product covariate */
                   1281: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1282: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1283: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1284: #define VD 10; /* Varying dummy covariate */
                   1285: #define VQ 11; /* Varying quantitative covariate */
                   1286: #define VP 12; /* Varying product covariate */
                   1287: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1288: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1289: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1290: #define APFD 16; /* Age product * fixed dummy covariate */
                   1291: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1292: #define APVD 18; /* Age product * varying dummy covariate */
                   1293: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1294: 
                   1295: #define FTYPE 1; /* Fixed covariate */
                   1296: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1297: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1298: 
                   1299: struct kmodel{
                   1300:        int maintype; /* main type */
                   1301:        int subtype; /* subtype */
                   1302: };
                   1303: struct kmodel modell[NCOVMAX];
                   1304: 
1.143     brouard  1305: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1306: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1307: 
                   1308: /**************** split *************************/
                   1309: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1310: {
                   1311:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1312:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1313:   */ 
                   1314:   char *ss;                            /* pointer */
1.186     brouard  1315:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1316: 
                   1317:   l1 = strlen(path );                  /* length of path */
                   1318:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1319:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1320:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1321:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1322:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1323:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1324:     /* get current working directory */
                   1325:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1326: #ifdef WIN32
                   1327:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1328: #else
                   1329:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1330: #endif
1.126     brouard  1331:       return( GLOCK_ERROR_GETCWD );
                   1332:     }
                   1333:     /* got dirc from getcwd*/
                   1334:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1335:   } else {                             /* strip directory from path */
1.126     brouard  1336:     ss++;                              /* after this, the filename */
                   1337:     l2 = strlen( ss );                 /* length of filename */
                   1338:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1339:     strcpy( name, ss );                /* save file name */
                   1340:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1341:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1342:     printf(" DIRC2 = %s \n",dirc);
                   1343:   }
                   1344:   /* We add a separator at the end of dirc if not exists */
                   1345:   l1 = strlen( dirc );                 /* length of directory */
                   1346:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1347:     dirc[l1] =  DIRSEPARATOR;
                   1348:     dirc[l1+1] = 0; 
                   1349:     printf(" DIRC3 = %s \n",dirc);
                   1350:   }
                   1351:   ss = strrchr( name, '.' );           /* find last / */
                   1352:   if (ss >0){
                   1353:     ss++;
                   1354:     strcpy(ext,ss);                    /* save extension */
                   1355:     l1= strlen( name);
                   1356:     l2= strlen(ss)+1;
                   1357:     strncpy( finame, name, l1-l2);
                   1358:     finame[l1-l2]= 0;
                   1359:   }
                   1360: 
                   1361:   return( 0 );                         /* we're done */
                   1362: }
                   1363: 
                   1364: 
                   1365: /******************************************/
                   1366: 
                   1367: void replace_back_to_slash(char *s, char*t)
                   1368: {
                   1369:   int i;
                   1370:   int lg=0;
                   1371:   i=0;
                   1372:   lg=strlen(t);
                   1373:   for(i=0; i<= lg; i++) {
                   1374:     (s[i] = t[i]);
                   1375:     if (t[i]== '\\') s[i]='/';
                   1376:   }
                   1377: }
                   1378: 
1.132     brouard  1379: char *trimbb(char *out, char *in)
1.137     brouard  1380: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1381:   char *s;
                   1382:   s=out;
                   1383:   while (*in != '\0'){
1.137     brouard  1384:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1385:       in++;
                   1386:     }
                   1387:     *out++ = *in++;
                   1388:   }
                   1389:   *out='\0';
                   1390:   return s;
                   1391: }
                   1392: 
1.187     brouard  1393: /* char *substrchaine(char *out, char *in, char *chain) */
                   1394: /* { */
                   1395: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1396: /*   char *s, *t; */
                   1397: /*   t=in;s=out; */
                   1398: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1399: /*     *out++ = *in++; */
                   1400: /*   } */
                   1401: 
                   1402: /*   /\* *in matches *chain *\/ */
                   1403: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1404: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1405: /*   } */
                   1406: /*   in--; chain--; */
                   1407: /*   while ( (*in != '\0')){ */
                   1408: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1409: /*     *out++ = *in++; */
                   1410: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1411: /*   } */
                   1412: /*   *out='\0'; */
                   1413: /*   out=s; */
                   1414: /*   return out; */
                   1415: /* } */
                   1416: char *substrchaine(char *out, char *in, char *chain)
                   1417: {
                   1418:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1419:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1420: 
                   1421:   char *strloc;
                   1422: 
                   1423:   strcpy (out, in); 
                   1424:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1425:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1426:   if(strloc != NULL){ 
                   1427:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1428:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1429:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1430:   }
                   1431:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1432:   return out;
                   1433: }
                   1434: 
                   1435: 
1.145     brouard  1436: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1437: {
1.187     brouard  1438:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1439:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1440:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1441:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1442:   */
1.160     brouard  1443:   char *s, *t;
1.145     brouard  1444:   t=in;s=in;
                   1445:   while ((*in != occ) && (*in != '\0')){
                   1446:     *alocc++ = *in++;
                   1447:   }
                   1448:   if( *in == occ){
                   1449:     *(alocc)='\0';
                   1450:     s=++in;
                   1451:   }
                   1452:  
                   1453:   if (s == t) {/* occ not found */
                   1454:     *(alocc-(in-s))='\0';
                   1455:     in=s;
                   1456:   }
                   1457:   while ( *in != '\0'){
                   1458:     *blocc++ = *in++;
                   1459:   }
                   1460: 
                   1461:   *blocc='\0';
                   1462:   return t;
                   1463: }
1.137     brouard  1464: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1465: {
1.187     brouard  1466:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1467:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1468:      gives blocc="abcdef2ghi" and alocc="j".
                   1469:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1470:   */
                   1471:   char *s, *t;
                   1472:   t=in;s=in;
                   1473:   while (*in != '\0'){
                   1474:     while( *in == occ){
                   1475:       *blocc++ = *in++;
                   1476:       s=in;
                   1477:     }
                   1478:     *blocc++ = *in++;
                   1479:   }
                   1480:   if (s == t) /* occ not found */
                   1481:     *(blocc-(in-s))='\0';
                   1482:   else
                   1483:     *(blocc-(in-s)-1)='\0';
                   1484:   in=s;
                   1485:   while ( *in != '\0'){
                   1486:     *alocc++ = *in++;
                   1487:   }
                   1488: 
                   1489:   *alocc='\0';
                   1490:   return s;
                   1491: }
                   1492: 
1.126     brouard  1493: int nbocc(char *s, char occ)
                   1494: {
                   1495:   int i,j=0;
                   1496:   int lg=20;
                   1497:   i=0;
                   1498:   lg=strlen(s);
                   1499:   for(i=0; i<= lg; i++) {
1.234     brouard  1500:     if  (s[i] == occ ) j++;
1.126     brouard  1501:   }
                   1502:   return j;
                   1503: }
                   1504: 
1.137     brouard  1505: /* void cutv(char *u,char *v, char*t, char occ) */
                   1506: /* { */
                   1507: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1508: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1509: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1510: /*   int i,lg,j,p=0; */
                   1511: /*   i=0; */
                   1512: /*   lg=strlen(t); */
                   1513: /*   for(j=0; j<=lg-1; j++) { */
                   1514: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1515: /*   } */
1.126     brouard  1516: 
1.137     brouard  1517: /*   for(j=0; j<p; j++) { */
                   1518: /*     (u[j] = t[j]); */
                   1519: /*   } */
                   1520: /*      u[p]='\0'; */
1.126     brouard  1521: 
1.137     brouard  1522: /*    for(j=0; j<= lg; j++) { */
                   1523: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1524: /*   } */
                   1525: /* } */
1.126     brouard  1526: 
1.160     brouard  1527: #ifdef _WIN32
                   1528: char * strsep(char **pp, const char *delim)
                   1529: {
                   1530:   char *p, *q;
                   1531:          
                   1532:   if ((p = *pp) == NULL)
                   1533:     return 0;
                   1534:   if ((q = strpbrk (p, delim)) != NULL)
                   1535:   {
                   1536:     *pp = q + 1;
                   1537:     *q = '\0';
                   1538:   }
                   1539:   else
                   1540:     *pp = 0;
                   1541:   return p;
                   1542: }
                   1543: #endif
                   1544: 
1.126     brouard  1545: /********************** nrerror ********************/
                   1546: 
                   1547: void nrerror(char error_text[])
                   1548: {
                   1549:   fprintf(stderr,"ERREUR ...\n");
                   1550:   fprintf(stderr,"%s\n",error_text);
                   1551:   exit(EXIT_FAILURE);
                   1552: }
                   1553: /*********************** vector *******************/
                   1554: double *vector(int nl, int nh)
                   1555: {
                   1556:   double *v;
                   1557:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1558:   if (!v) nrerror("allocation failure in vector");
                   1559:   return v-nl+NR_END;
                   1560: }
                   1561: 
                   1562: /************************ free vector ******************/
                   1563: void free_vector(double*v, int nl, int nh)
                   1564: {
                   1565:   free((FREE_ARG)(v+nl-NR_END));
                   1566: }
                   1567: 
                   1568: /************************ivector *******************************/
                   1569: int *ivector(long nl,long nh)
                   1570: {
                   1571:   int *v;
                   1572:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1573:   if (!v) nrerror("allocation failure in ivector");
                   1574:   return v-nl+NR_END;
                   1575: }
                   1576: 
                   1577: /******************free ivector **************************/
                   1578: void free_ivector(int *v, long nl, long nh)
                   1579: {
                   1580:   free((FREE_ARG)(v+nl-NR_END));
                   1581: }
                   1582: 
                   1583: /************************lvector *******************************/
                   1584: long *lvector(long nl,long nh)
                   1585: {
                   1586:   long *v;
                   1587:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1588:   if (!v) nrerror("allocation failure in ivector");
                   1589:   return v-nl+NR_END;
                   1590: }
                   1591: 
                   1592: /******************free lvector **************************/
                   1593: void free_lvector(long *v, long nl, long nh)
                   1594: {
                   1595:   free((FREE_ARG)(v+nl-NR_END));
                   1596: }
                   1597: 
                   1598: /******************* imatrix *******************************/
                   1599: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1600:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1601: { 
                   1602:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1603:   int **m; 
                   1604:   
                   1605:   /* allocate pointers to rows */ 
                   1606:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1607:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1608:   m += NR_END; 
                   1609:   m -= nrl; 
                   1610:   
                   1611:   
                   1612:   /* allocate rows and set pointers to them */ 
                   1613:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1614:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1615:   m[nrl] += NR_END; 
                   1616:   m[nrl] -= ncl; 
                   1617:   
                   1618:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1619:   
                   1620:   /* return pointer to array of pointers to rows */ 
                   1621:   return m; 
                   1622: } 
                   1623: 
                   1624: /****************** free_imatrix *************************/
                   1625: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1626:       int **m;
                   1627:       long nch,ncl,nrh,nrl; 
                   1628:      /* free an int matrix allocated by imatrix() */ 
                   1629: { 
                   1630:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1631:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1632: } 
                   1633: 
                   1634: /******************* matrix *******************************/
                   1635: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1636: {
                   1637:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1638:   double **m;
                   1639: 
                   1640:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1641:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1642:   m += NR_END;
                   1643:   m -= nrl;
                   1644: 
                   1645:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1646:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1647:   m[nrl] += NR_END;
                   1648:   m[nrl] -= ncl;
                   1649: 
                   1650:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1651:   return m;
1.145     brouard  1652:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1653: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1654: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1655:    */
                   1656: }
                   1657: 
                   1658: /*************************free matrix ************************/
                   1659: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1660: {
                   1661:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1662:   free((FREE_ARG)(m+nrl-NR_END));
                   1663: }
                   1664: 
                   1665: /******************* ma3x *******************************/
                   1666: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1667: {
                   1668:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1669:   double ***m;
                   1670: 
                   1671:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1672:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1673:   m += NR_END;
                   1674:   m -= nrl;
                   1675: 
                   1676:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1677:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1678:   m[nrl] += NR_END;
                   1679:   m[nrl] -= ncl;
                   1680: 
                   1681:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1682: 
                   1683:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1684:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1685:   m[nrl][ncl] += NR_END;
                   1686:   m[nrl][ncl] -= nll;
                   1687:   for (j=ncl+1; j<=nch; j++) 
                   1688:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1689:   
                   1690:   for (i=nrl+1; i<=nrh; i++) {
                   1691:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1692:     for (j=ncl+1; j<=nch; j++) 
                   1693:       m[i][j]=m[i][j-1]+nlay;
                   1694:   }
                   1695:   return m; 
                   1696:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1697:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1698:   */
                   1699: }
                   1700: 
                   1701: /*************************free ma3x ************************/
                   1702: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1703: {
                   1704:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1705:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1706:   free((FREE_ARG)(m+nrl-NR_END));
                   1707: }
                   1708: 
                   1709: /*************** function subdirf ***********/
                   1710: char *subdirf(char fileres[])
                   1711: {
                   1712:   /* Caution optionfilefiname is hidden */
                   1713:   strcpy(tmpout,optionfilefiname);
                   1714:   strcat(tmpout,"/"); /* Add to the right */
                   1715:   strcat(tmpout,fileres);
                   1716:   return tmpout;
                   1717: }
                   1718: 
                   1719: /*************** function subdirf2 ***********/
                   1720: char *subdirf2(char fileres[], char *preop)
                   1721: {
                   1722:   
                   1723:   /* Caution optionfilefiname is hidden */
                   1724:   strcpy(tmpout,optionfilefiname);
                   1725:   strcat(tmpout,"/");
                   1726:   strcat(tmpout,preop);
                   1727:   strcat(tmpout,fileres);
                   1728:   return tmpout;
                   1729: }
                   1730: 
                   1731: /*************** function subdirf3 ***********/
                   1732: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1733: {
                   1734:   
                   1735:   /* Caution optionfilefiname is hidden */
                   1736:   strcpy(tmpout,optionfilefiname);
                   1737:   strcat(tmpout,"/");
                   1738:   strcat(tmpout,preop);
                   1739:   strcat(tmpout,preop2);
                   1740:   strcat(tmpout,fileres);
                   1741:   return tmpout;
                   1742: }
1.213     brouard  1743:  
                   1744: /*************** function subdirfext ***********/
                   1745: char *subdirfext(char fileres[], char *preop, char *postop)
                   1746: {
                   1747:   
                   1748:   strcpy(tmpout,preop);
                   1749:   strcat(tmpout,fileres);
                   1750:   strcat(tmpout,postop);
                   1751:   return tmpout;
                   1752: }
1.126     brouard  1753: 
1.213     brouard  1754: /*************** function subdirfext3 ***********/
                   1755: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1756: {
                   1757:   
                   1758:   /* Caution optionfilefiname is hidden */
                   1759:   strcpy(tmpout,optionfilefiname);
                   1760:   strcat(tmpout,"/");
                   1761:   strcat(tmpout,preop);
                   1762:   strcat(tmpout,fileres);
                   1763:   strcat(tmpout,postop);
                   1764:   return tmpout;
                   1765: }
                   1766:  
1.162     brouard  1767: char *asc_diff_time(long time_sec, char ascdiff[])
                   1768: {
                   1769:   long sec_left, days, hours, minutes;
                   1770:   days = (time_sec) / (60*60*24);
                   1771:   sec_left = (time_sec) % (60*60*24);
                   1772:   hours = (sec_left) / (60*60) ;
                   1773:   sec_left = (sec_left) %(60*60);
                   1774:   minutes = (sec_left) /60;
                   1775:   sec_left = (sec_left) % (60);
                   1776:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1777:   return ascdiff;
                   1778: }
                   1779: 
1.126     brouard  1780: /***************** f1dim *************************/
                   1781: extern int ncom; 
                   1782: extern double *pcom,*xicom;
                   1783: extern double (*nrfunc)(double []); 
                   1784:  
                   1785: double f1dim(double x) 
                   1786: { 
                   1787:   int j; 
                   1788:   double f;
                   1789:   double *xt; 
                   1790:  
                   1791:   xt=vector(1,ncom); 
                   1792:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1793:   f=(*nrfunc)(xt); 
                   1794:   free_vector(xt,1,ncom); 
                   1795:   return f; 
                   1796: } 
                   1797: 
                   1798: /*****************brent *************************/
                   1799: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1800: {
                   1801:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1802:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1803:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1804:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1805:    * returned function value. 
                   1806:   */
1.126     brouard  1807:   int iter; 
                   1808:   double a,b,d,etemp;
1.159     brouard  1809:   double fu=0,fv,fw,fx;
1.164     brouard  1810:   double ftemp=0.;
1.126     brouard  1811:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1812:   double e=0.0; 
                   1813:  
                   1814:   a=(ax < cx ? ax : cx); 
                   1815:   b=(ax > cx ? ax : cx); 
                   1816:   x=w=v=bx; 
                   1817:   fw=fv=fx=(*f)(x); 
                   1818:   for (iter=1;iter<=ITMAX;iter++) { 
                   1819:     xm=0.5*(a+b); 
                   1820:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1821:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1822:     printf(".");fflush(stdout);
                   1823:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1824: #ifdef DEBUGBRENT
1.126     brouard  1825:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1826:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1827:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1828: #endif
                   1829:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1830:       *xmin=x; 
                   1831:       return fx; 
                   1832:     } 
                   1833:     ftemp=fu;
                   1834:     if (fabs(e) > tol1) { 
                   1835:       r=(x-w)*(fx-fv); 
                   1836:       q=(x-v)*(fx-fw); 
                   1837:       p=(x-v)*q-(x-w)*r; 
                   1838:       q=2.0*(q-r); 
                   1839:       if (q > 0.0) p = -p; 
                   1840:       q=fabs(q); 
                   1841:       etemp=e; 
                   1842:       e=d; 
                   1843:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1844:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1845:       else { 
1.224     brouard  1846:                                d=p/q; 
                   1847:                                u=x+d; 
                   1848:                                if (u-a < tol2 || b-u < tol2) 
                   1849:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1850:       } 
                   1851:     } else { 
                   1852:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1853:     } 
                   1854:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1855:     fu=(*f)(u); 
                   1856:     if (fu <= fx) { 
                   1857:       if (u >= x) a=x; else b=x; 
                   1858:       SHFT(v,w,x,u) 
1.183     brouard  1859:       SHFT(fv,fw,fx,fu) 
                   1860:     } else { 
                   1861:       if (u < x) a=u; else b=u; 
                   1862:       if (fu <= fw || w == x) { 
1.224     brouard  1863:                                v=w; 
                   1864:                                w=u; 
                   1865:                                fv=fw; 
                   1866:                                fw=fu; 
1.183     brouard  1867:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1868:                                v=u; 
                   1869:                                fv=fu; 
1.183     brouard  1870:       } 
                   1871:     } 
1.126     brouard  1872:   } 
                   1873:   nrerror("Too many iterations in brent"); 
                   1874:   *xmin=x; 
                   1875:   return fx; 
                   1876: } 
                   1877: 
                   1878: /****************** mnbrak ***********************/
                   1879: 
                   1880: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1881:            double (*func)(double)) 
1.183     brouard  1882: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1883: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1884: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1885: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1886:    */
1.126     brouard  1887:   double ulim,u,r,q, dum;
                   1888:   double fu; 
1.187     brouard  1889: 
                   1890:   double scale=10.;
                   1891:   int iterscale=0;
                   1892: 
                   1893:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1894:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1895: 
                   1896: 
                   1897:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1898:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1899:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1900:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1901:   /* } */
                   1902: 
1.126     brouard  1903:   if (*fb > *fa) { 
                   1904:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1905:     SHFT(dum,*fb,*fa,dum) 
                   1906:   } 
1.126     brouard  1907:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1908:   *fc=(*func)(*cx); 
1.183     brouard  1909: #ifdef DEBUG
1.224     brouard  1910:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1911:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1912: #endif
1.224     brouard  1913:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1914:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1915:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1916:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1917:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1918:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1919:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1920:       fu=(*func)(u); 
1.163     brouard  1921: #ifdef DEBUG
                   1922:       /* f(x)=A(x-u)**2+f(u) */
                   1923:       double A, fparabu; 
                   1924:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1925:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1926:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1927:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1928:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1929:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1930:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1931:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1932: #endif 
1.184     brouard  1933: #ifdef MNBRAKORIGINAL
1.183     brouard  1934: #else
1.191     brouard  1935: /*       if (fu > *fc) { */
                   1936: /* #ifdef DEBUG */
                   1937: /*       printf("mnbrak4  fu > fc \n"); */
                   1938: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1939: /* #endif */
                   1940: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1941: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1942: /*     dum=u; /\* Shifting c and u *\/ */
                   1943: /*     u = *cx; */
                   1944: /*     *cx = dum; */
                   1945: /*     dum = fu; */
                   1946: /*     fu = *fc; */
                   1947: /*     *fc =dum; */
                   1948: /*       } else { /\* end *\/ */
                   1949: /* #ifdef DEBUG */
                   1950: /*       printf("mnbrak3  fu < fc \n"); */
                   1951: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1952: /* #endif */
                   1953: /*     dum=u; /\* Shifting c and u *\/ */
                   1954: /*     u = *cx; */
                   1955: /*     *cx = dum; */
                   1956: /*     dum = fu; */
                   1957: /*     fu = *fc; */
                   1958: /*     *fc =dum; */
                   1959: /*       } */
1.224     brouard  1960: #ifdef DEBUGMNBRAK
                   1961:                 double A, fparabu; 
                   1962:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1963:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1964:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1965:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1966: #endif
1.191     brouard  1967:       dum=u; /* Shifting c and u */
                   1968:       u = *cx;
                   1969:       *cx = dum;
                   1970:       dum = fu;
                   1971:       fu = *fc;
                   1972:       *fc =dum;
1.183     brouard  1973: #endif
1.162     brouard  1974:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1975: #ifdef DEBUG
1.224     brouard  1976:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1977:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1978: #endif
1.126     brouard  1979:       fu=(*func)(u); 
                   1980:       if (fu < *fc) { 
1.183     brouard  1981: #ifdef DEBUG
1.224     brouard  1982:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1983:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1984: #endif
                   1985:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1986:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1987: #ifdef DEBUG
                   1988:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1989: #endif
                   1990:       } 
1.162     brouard  1991:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1992: #ifdef DEBUG
1.224     brouard  1993:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1994:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1995: #endif
1.126     brouard  1996:       u=ulim; 
                   1997:       fu=(*func)(u); 
1.183     brouard  1998:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1999: #ifdef DEBUG
1.224     brouard  2000:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2001:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2002: #endif
1.126     brouard  2003:       u=(*cx)+GOLD*(*cx-*bx); 
                   2004:       fu=(*func)(u); 
1.224     brouard  2005: #ifdef DEBUG
                   2006:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2007:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2008: #endif
1.183     brouard  2009:     } /* end tests */
1.126     brouard  2010:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2011:     SHFT(*fa,*fb,*fc,fu) 
                   2012: #ifdef DEBUG
1.224     brouard  2013:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2014:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2015: #endif
                   2016:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2017: } 
                   2018: 
                   2019: /*************** linmin ************************/
1.162     brouard  2020: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2021: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2022: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2023: the value of func at the returned location p . This is actually all accomplished by calling the
                   2024: routines mnbrak and brent .*/
1.126     brouard  2025: int ncom; 
                   2026: double *pcom,*xicom;
                   2027: double (*nrfunc)(double []); 
                   2028:  
1.224     brouard  2029: #ifdef LINMINORIGINAL
1.126     brouard  2030: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2031: #else
                   2032: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2033: #endif
1.126     brouard  2034: { 
                   2035:   double brent(double ax, double bx, double cx, 
                   2036:               double (*f)(double), double tol, double *xmin); 
                   2037:   double f1dim(double x); 
                   2038:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2039:              double *fc, double (*func)(double)); 
                   2040:   int j; 
                   2041:   double xx,xmin,bx,ax; 
                   2042:   double fx,fb,fa;
1.187     brouard  2043: 
1.203     brouard  2044: #ifdef LINMINORIGINAL
                   2045: #else
                   2046:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2047: #endif
                   2048:   
1.126     brouard  2049:   ncom=n; 
                   2050:   pcom=vector(1,n); 
                   2051:   xicom=vector(1,n); 
                   2052:   nrfunc=func; 
                   2053:   for (j=1;j<=n;j++) { 
                   2054:     pcom[j]=p[j]; 
1.202     brouard  2055:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2056:   } 
1.187     brouard  2057: 
1.203     brouard  2058: #ifdef LINMINORIGINAL
                   2059:   xx=1.;
                   2060: #else
                   2061:   axs=0.0;
                   2062:   xxs=1.;
                   2063:   do{
                   2064:     xx= xxs;
                   2065: #endif
1.187     brouard  2066:     ax=0.;
                   2067:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2068:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2069:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2070:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2071:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2072:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2073:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2074: #ifdef LINMINORIGINAL
                   2075: #else
                   2076:     if (fx != fx){
1.224     brouard  2077:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2078:                        printf("|");
                   2079:                        fprintf(ficlog,"|");
1.203     brouard  2080: #ifdef DEBUGLINMIN
1.224     brouard  2081:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2082: #endif
                   2083:     }
1.224     brouard  2084:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2085: #endif
                   2086:   
1.191     brouard  2087: #ifdef DEBUGLINMIN
                   2088:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2089:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2090: #endif
1.224     brouard  2091: #ifdef LINMINORIGINAL
                   2092: #else
                   2093:        if(fb == fx){ /* Flat function in the direction */
                   2094:                xmin=xx;
                   2095:     *flat=1;
                   2096:        }else{
                   2097:     *flat=0;
                   2098: #endif
                   2099:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2100:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2101:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2102:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2103:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2104:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2105: #ifdef DEBUG
1.224     brouard  2106:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2107:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2108: #endif
                   2109: #ifdef LINMINORIGINAL
                   2110: #else
                   2111:                        }
1.126     brouard  2112: #endif
1.191     brouard  2113: #ifdef DEBUGLINMIN
                   2114:   printf("linmin end ");
1.202     brouard  2115:   fprintf(ficlog,"linmin end ");
1.191     brouard  2116: #endif
1.126     brouard  2117:   for (j=1;j<=n;j++) { 
1.203     brouard  2118: #ifdef LINMINORIGINAL
                   2119:     xi[j] *= xmin; 
                   2120: #else
                   2121: #ifdef DEBUGLINMIN
                   2122:     if(xxs <1.0)
                   2123:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2124: #endif
                   2125:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2126: #ifdef DEBUGLINMIN
                   2127:     if(xxs <1.0)
                   2128:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2129: #endif
                   2130: #endif
1.187     brouard  2131:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2132:   } 
1.191     brouard  2133: #ifdef DEBUGLINMIN
1.203     brouard  2134:   printf("\n");
1.191     brouard  2135:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2136:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2137:   for (j=1;j<=n;j++) { 
1.202     brouard  2138:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2139:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2140:     if(j % ncovmodel == 0){
1.191     brouard  2141:       printf("\n");
1.202     brouard  2142:       fprintf(ficlog,"\n");
                   2143:     }
1.191     brouard  2144:   }
1.203     brouard  2145: #else
1.191     brouard  2146: #endif
1.126     brouard  2147:   free_vector(xicom,1,n); 
                   2148:   free_vector(pcom,1,n); 
                   2149: } 
                   2150: 
                   2151: 
                   2152: /*************** powell ************************/
1.162     brouard  2153: /*
                   2154: Minimization of a function func of n variables. Input consists of an initial starting point
                   2155: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2156: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2157: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2158: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2159: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2160:  */
1.224     brouard  2161: #ifdef LINMINORIGINAL
                   2162: #else
                   2163:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2164:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2165: #endif
1.126     brouard  2166: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2167:            double (*func)(double [])) 
                   2168: { 
1.224     brouard  2169: #ifdef LINMINORIGINAL
                   2170:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2171:              double (*func)(double [])); 
1.224     brouard  2172: #else 
1.241     brouard  2173:  void linmin(double p[], double xi[], int n, double *fret,
                   2174:             double (*func)(double []),int *flat); 
1.224     brouard  2175: #endif
1.239     brouard  2176:  int i,ibig,j,jk,k; 
1.126     brouard  2177:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2178:   double directest;
1.126     brouard  2179:   double fp,fptt;
                   2180:   double *xits;
                   2181:   int niterf, itmp;
1.224     brouard  2182: #ifdef LINMINORIGINAL
                   2183: #else
                   2184: 
                   2185:   flatdir=ivector(1,n); 
                   2186:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2187: #endif
1.126     brouard  2188: 
                   2189:   pt=vector(1,n); 
                   2190:   ptt=vector(1,n); 
                   2191:   xit=vector(1,n); 
                   2192:   xits=vector(1,n); 
                   2193:   *fret=(*func)(p); 
                   2194:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2195:   rcurr_time = time(NULL);  
1.126     brouard  2196:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2197:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2198:     ibig=0; 
                   2199:     del=0.0; 
1.157     brouard  2200:     rlast_time=rcurr_time;
                   2201:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2202:     rcurr_time = time(NULL);  
                   2203:     curr_time = *localtime(&rcurr_time);
                   2204:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2205:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2206: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2207:     for (i=1;i<=n;i++) {
1.126     brouard  2208:       fprintf(ficrespow," %.12lf", p[i]);
                   2209:     }
1.239     brouard  2210:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2211:     printf("\n#model=  1      +     age ");
                   2212:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2213:     if(nagesqr==1){
1.241     brouard  2214:        printf("  + age*age  ");
                   2215:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2216:     }
                   2217:     for(j=1;j <=ncovmodel-2;j++){
                   2218:       if(Typevar[j]==0) {
                   2219:        printf("  +      V%d  ",Tvar[j]);
                   2220:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2221:       }else if(Typevar[j]==1) {
                   2222:        printf("  +    V%d*age ",Tvar[j]);
                   2223:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2224:       }else if(Typevar[j]==2) {
                   2225:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2226:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2227:       }
                   2228:     }
1.126     brouard  2229:     printf("\n");
1.239     brouard  2230: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2231: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2232:     fprintf(ficlog,"\n");
1.239     brouard  2233:     for(i=1,jk=1; i <=nlstate; i++){
                   2234:       for(k=1; k <=(nlstate+ndeath); k++){
                   2235:        if (k != i) {
                   2236:          printf("%d%d ",i,k);
                   2237:          fprintf(ficlog,"%d%d ",i,k);
                   2238:          for(j=1; j <=ncovmodel; j++){
                   2239:            printf("%12.7f ",p[jk]);
                   2240:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2241:            jk++; 
                   2242:          }
                   2243:          printf("\n");
                   2244:          fprintf(ficlog,"\n");
                   2245:        }
                   2246:       }
                   2247:     }
1.241     brouard  2248:     if(*iter <=3 && *iter >1){
1.157     brouard  2249:       tml = *localtime(&rcurr_time);
                   2250:       strcpy(strcurr,asctime(&tml));
                   2251:       rforecast_time=rcurr_time; 
1.126     brouard  2252:       itmp = strlen(strcurr);
                   2253:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2254:        strcurr[itmp-1]='\0';
1.162     brouard  2255:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2256:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2257:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2258:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2259:        forecast_time = *localtime(&rforecast_time);
                   2260:        strcpy(strfor,asctime(&forecast_time));
                   2261:        itmp = strlen(strfor);
                   2262:        if(strfor[itmp-1]=='\n')
                   2263:          strfor[itmp-1]='\0';
                   2264:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2265:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2266:       }
                   2267:     }
1.187     brouard  2268:     for (i=1;i<=n;i++) { /* For each direction i */
                   2269:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2270:       fptt=(*fret); 
                   2271: #ifdef DEBUG
1.203     brouard  2272:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2273:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2274: #endif
1.203     brouard  2275:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2276:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2277: #ifdef LINMINORIGINAL
1.188     brouard  2278:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2279: #else
                   2280:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2281:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2282: #endif
                   2283:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2284:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2285:                                /* because that direction will be replaced unless the gain del is small */
                   2286:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2287:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2288:                                /* with the new direction. */
                   2289:                                del=fabs(fptt-(*fret)); 
                   2290:                                ibig=i; 
1.126     brouard  2291:       } 
                   2292: #ifdef DEBUG
                   2293:       printf("%d %.12e",i,(*fret));
                   2294:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2295:       for (j=1;j<=n;j++) {
1.224     brouard  2296:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2297:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2298:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2299:       }
                   2300:       for(j=1;j<=n;j++) {
1.225     brouard  2301:                                printf(" p(%d)=%.12e",j,p[j]);
                   2302:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2303:       }
                   2304:       printf("\n");
                   2305:       fprintf(ficlog,"\n");
                   2306: #endif
1.187     brouard  2307:     } /* end loop on each direction i */
                   2308:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2309:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2310:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2311:       for(j=1;j<=n;j++) {
1.225     brouard  2312:                                if(flatdir[j] >0){
                   2313:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2314:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2315:                                }
                   2316:                                /* printf("\n"); */
                   2317:                                /* fprintf(ficlog,"\n"); */
                   2318:                        }
1.243     brouard  2319:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2320:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2321:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2322:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2323:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2324:       /* decreased of more than 3.84  */
                   2325:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2326:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2327:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2328:                        
1.188     brouard  2329:       /* Starting the program with initial values given by a former maximization will simply change */
                   2330:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2331:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2332:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2333: #ifdef DEBUG
                   2334:       int k[2],l;
                   2335:       k[0]=1;
                   2336:       k[1]=-1;
                   2337:       printf("Max: %.12e",(*func)(p));
                   2338:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2339:       for (j=1;j<=n;j++) {
                   2340:        printf(" %.12e",p[j]);
                   2341:        fprintf(ficlog," %.12e",p[j]);
                   2342:       }
                   2343:       printf("\n");
                   2344:       fprintf(ficlog,"\n");
                   2345:       for(l=0;l<=1;l++) {
                   2346:        for (j=1;j<=n;j++) {
                   2347:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2348:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2349:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2350:        }
                   2351:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2352:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2353:       }
                   2354: #endif
                   2355: 
1.224     brouard  2356: #ifdef LINMINORIGINAL
                   2357: #else
                   2358:       free_ivector(flatdir,1,n); 
                   2359: #endif
1.126     brouard  2360:       free_vector(xit,1,n); 
                   2361:       free_vector(xits,1,n); 
                   2362:       free_vector(ptt,1,n); 
                   2363:       free_vector(pt,1,n); 
                   2364:       return; 
1.192     brouard  2365:     } /* enough precision */ 
1.240     brouard  2366:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2367:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2368:       ptt[j]=2.0*p[j]-pt[j]; 
                   2369:       xit[j]=p[j]-pt[j]; 
                   2370:       pt[j]=p[j]; 
                   2371:     } 
1.181     brouard  2372:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2373: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2374:                if (*iter <=4) {
1.225     brouard  2375: #else
                   2376: #endif
1.224     brouard  2377: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2378: #else
1.161     brouard  2379:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2380: #endif
1.162     brouard  2381:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2382:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2383:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2384:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2385:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2386:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2387:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2388:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2389:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2390:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2391:       /* mu² and del² are equal when f3=f1 */
                   2392:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2393:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2394:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2395:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2396: #ifdef NRCORIGINAL
                   2397:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2398: #else
                   2399:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2400:       t= t- del*SQR(fp-fptt);
1.183     brouard  2401: #endif
1.202     brouard  2402:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2403: #ifdef DEBUG
1.181     brouard  2404:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2405:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2406:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2407:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2408:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2409:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2410:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2411:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2412: #endif
1.183     brouard  2413: #ifdef POWELLORIGINAL
                   2414:       if (t < 0.0) { /* Then we use it for new direction */
                   2415: #else
1.182     brouard  2416:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2417:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2418:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2419:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2420:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2421:       } 
1.181     brouard  2422:       if (directest < 0.0) { /* Then we use it for new direction */
                   2423: #endif
1.191     brouard  2424: #ifdef DEBUGLINMIN
1.234     brouard  2425:        printf("Before linmin in direction P%d-P0\n",n);
                   2426:        for (j=1;j<=n;j++) {
                   2427:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2428:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2429:          if(j % ncovmodel == 0){
                   2430:            printf("\n");
                   2431:            fprintf(ficlog,"\n");
                   2432:          }
                   2433:        }
1.224     brouard  2434: #endif
                   2435: #ifdef LINMINORIGINAL
1.234     brouard  2436:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2437: #else
1.234     brouard  2438:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2439:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2440: #endif
1.234     brouard  2441:        
1.191     brouard  2442: #ifdef DEBUGLINMIN
1.234     brouard  2443:        for (j=1;j<=n;j++) { 
                   2444:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2445:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2446:          if(j % ncovmodel == 0){
                   2447:            printf("\n");
                   2448:            fprintf(ficlog,"\n");
                   2449:          }
                   2450:        }
1.224     brouard  2451: #endif
1.234     brouard  2452:        for (j=1;j<=n;j++) { 
                   2453:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2454:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2455:        }
1.224     brouard  2456: #ifdef LINMINORIGINAL
                   2457: #else
1.234     brouard  2458:        for (j=1, flatd=0;j<=n;j++) {
                   2459:          if(flatdir[j]>0)
                   2460:            flatd++;
                   2461:        }
                   2462:        if(flatd >0){
1.255     brouard  2463:          printf("%d flat directions: ",flatd);
                   2464:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2465:          for (j=1;j<=n;j++) { 
                   2466:            if(flatdir[j]>0){
                   2467:              printf("%d ",j);
                   2468:              fprintf(ficlog,"%d ",j);
                   2469:            }
                   2470:          }
                   2471:          printf("\n");
                   2472:          fprintf(ficlog,"\n");
                   2473:        }
1.191     brouard  2474: #endif
1.234     brouard  2475:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2476:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2477:        
1.126     brouard  2478: #ifdef DEBUG
1.234     brouard  2479:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2480:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2481:        for(j=1;j<=n;j++){
                   2482:          printf(" %lf",xit[j]);
                   2483:          fprintf(ficlog," %lf",xit[j]);
                   2484:        }
                   2485:        printf("\n");
                   2486:        fprintf(ficlog,"\n");
1.126     brouard  2487: #endif
1.192     brouard  2488:       } /* end of t or directest negative */
1.224     brouard  2489: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2490: #else
1.234     brouard  2491:       } /* end if (fptt < fp)  */
1.192     brouard  2492: #endif
1.225     brouard  2493: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2494:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2495: #else
1.224     brouard  2496: #endif
1.234     brouard  2497:                } /* loop iteration */ 
1.126     brouard  2498: } 
1.234     brouard  2499:   
1.126     brouard  2500: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2501:   
1.235     brouard  2502:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2503:   {
1.235     brouard  2504:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2505:        (and selected quantitative values in nres)
                   2506:        by left multiplying the unit
1.234     brouard  2507:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2508:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2509:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2510:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2511:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2512:   /* Initial matrix pimij */
                   2513:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2514:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2515:   /*  0,                   0                  , 1} */
                   2516:   /*
                   2517:    * and after some iteration: */
                   2518:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2519:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2520:   /*  0,                   0                  , 1} */
                   2521:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2522:   /* {0.51571254859325999, 0.4842874514067399, */
                   2523:   /*  0.51326036147820708, 0.48673963852179264} */
                   2524:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2525:     
1.126     brouard  2526:   int i, ii,j,k;
1.209     brouard  2527:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2528:   /* double **matprod2(); */ /* test */
1.218     brouard  2529:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2530:   double **newm;
1.209     brouard  2531:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2532:   int ncvloop=0;
1.169     brouard  2533:   
1.209     brouard  2534:   min=vector(1,nlstate);
                   2535:   max=vector(1,nlstate);
                   2536:   meandiff=vector(1,nlstate);
                   2537: 
1.218     brouard  2538:        /* Starting with matrix unity */
1.126     brouard  2539:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2540:     for (j=1;j<=nlstate+ndeath;j++){
                   2541:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2542:     }
1.169     brouard  2543:   
                   2544:   cov[1]=1.;
                   2545:   
                   2546:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2547:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2548:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2549:     ncvloop++;
1.126     brouard  2550:     newm=savm;
                   2551:     /* Covariates have to be included here again */
1.138     brouard  2552:     cov[2]=agefin;
1.187     brouard  2553:     if(nagesqr==1)
                   2554:       cov[3]= agefin*agefin;;
1.234     brouard  2555:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2556:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2557:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2558:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2559:     }
                   2560:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2561:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2562:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2563:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2564:     }
1.237     brouard  2565:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2566:       if(Dummy[Tvar[Tage[k]]]){
                   2567:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2568:       } else{
1.235     brouard  2569:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2570:       }
1.235     brouard  2571:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2572:     }
1.237     brouard  2573:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2574:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2575:       if(Dummy[Tvard[k][1]==0]){
                   2576:        if(Dummy[Tvard[k][2]==0]){
                   2577:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2578:        }else{
                   2579:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2580:        }
                   2581:       }else{
                   2582:        if(Dummy[Tvard[k][2]==0]){
                   2583:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2584:        }else{
                   2585:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2586:        }
                   2587:       }
1.234     brouard  2588:     }
1.138     brouard  2589:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2590:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2591:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2592:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2593:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2594:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2595:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2596:     
1.126     brouard  2597:     savm=oldm;
                   2598:     oldm=newm;
1.209     brouard  2599: 
                   2600:     for(j=1; j<=nlstate; j++){
                   2601:       max[j]=0.;
                   2602:       min[j]=1.;
                   2603:     }
                   2604:     for(i=1;i<=nlstate;i++){
                   2605:       sumnew=0;
                   2606:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2607:       for(j=1; j<=nlstate; j++){ 
                   2608:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2609:        max[j]=FMAX(max[j],prlim[i][j]);
                   2610:        min[j]=FMIN(min[j],prlim[i][j]);
                   2611:       }
                   2612:     }
                   2613: 
1.126     brouard  2614:     maxmax=0.;
1.209     brouard  2615:     for(j=1; j<=nlstate; j++){
                   2616:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2617:       maxmax=FMAX(maxmax,meandiff[j]);
                   2618:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2619:     } /* j loop */
1.203     brouard  2620:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2621:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2622:     if(maxmax < ftolpl){
1.209     brouard  2623:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2624:       free_vector(min,1,nlstate);
                   2625:       free_vector(max,1,nlstate);
                   2626:       free_vector(meandiff,1,nlstate);
1.126     brouard  2627:       return prlim;
                   2628:     }
1.169     brouard  2629:   } /* age loop */
1.208     brouard  2630:     /* After some age loop it doesn't converge */
1.209     brouard  2631:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2632: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2633:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2634:   free_vector(min,1,nlstate);
                   2635:   free_vector(max,1,nlstate);
                   2636:   free_vector(meandiff,1,nlstate);
1.208     brouard  2637:   
1.169     brouard  2638:   return prlim; /* should not reach here */
1.126     brouard  2639: }
                   2640: 
1.217     brouard  2641: 
                   2642:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2643: 
1.218     brouard  2644:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2645:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2646:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2647: {
1.264     brouard  2648:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2649:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2650:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2651:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2652:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2653:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2654:   /* Initial matrix pimij */
                   2655:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2656:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2657:   /*  0,                   0                  , 1} */
                   2658:   /*
                   2659:    * and after some iteration: */
                   2660:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2661:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2662:   /*  0,                   0                  , 1} */
                   2663:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2664:   /* {0.51571254859325999, 0.4842874514067399, */
                   2665:   /*  0.51326036147820708, 0.48673963852179264} */
                   2666:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2667: 
                   2668:   int i, ii,j,k;
1.247     brouard  2669:   int first=0;
1.217     brouard  2670:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2671:   /* double **matprod2(); */ /* test */
                   2672:   double **out, cov[NCOVMAX+1], **bmij();
                   2673:   double **newm;
1.218     brouard  2674:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2675:   double        **oldm, **savm;  /* for use */
                   2676: 
1.217     brouard  2677:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2678:   int ncvloop=0;
                   2679:   
                   2680:   min=vector(1,nlstate);
                   2681:   max=vector(1,nlstate);
                   2682:   meandiff=vector(1,nlstate);
                   2683: 
1.266     brouard  2684:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2685:   oldm=oldms; savm=savms;
                   2686:   
                   2687:   /* Starting with matrix unity */
                   2688:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2689:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2690:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2691:     }
                   2692:   
                   2693:   cov[1]=1.;
                   2694:   
                   2695:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2696:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2697:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2698:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2699:     ncvloop++;
1.218     brouard  2700:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2701:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2702:     /* Covariates have to be included here again */
                   2703:     cov[2]=agefin;
                   2704:     if(nagesqr==1)
                   2705:       cov[3]= agefin*agefin;;
1.242     brouard  2706:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2707:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2708:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2709:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2710:     }
                   2711:     /* for (k=1; k<=cptcovn;k++) { */
                   2712:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2713:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2714:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2715:     /* } */
                   2716:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2717:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2718:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2719:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2720:     }
                   2721:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2722:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2723:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2724:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2725:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2726:       if(Dummy[Tvar[Tage[k]]]){
                   2727:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2728:       } else{
                   2729:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2730:       }
                   2731:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2732:     }
                   2733:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2734:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2735:       if(Dummy[Tvard[k][1]==0]){
                   2736:        if(Dummy[Tvard[k][2]==0]){
                   2737:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2738:        }else{
                   2739:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2740:        }
                   2741:       }else{
                   2742:        if(Dummy[Tvard[k][2]==0]){
                   2743:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2744:        }else{
                   2745:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2746:        }
                   2747:       }
1.217     brouard  2748:     }
                   2749:     
                   2750:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2751:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2752:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2753:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2754:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2755:                /* ij should be linked to the correct index of cov */
                   2756:                /* age and covariate values ij are in 'cov', but we need to pass
                   2757:                 * ij for the observed prevalence at age and status and covariate
                   2758:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2759:                 */
                   2760:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2761:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2762:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2763:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2764:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2765:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2766:     /*         printf("%d newm= ",i); */
                   2767:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2768:     /*           printf("%f ",newm[i][j]); */
                   2769:     /*         } */
                   2770:     /*         printf("oldm * "); */
                   2771:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2772:     /*           printf("%f ",oldm[i][j]); */
                   2773:     /*         } */
1.268     brouard  2774:     /*         printf(" bmmij "); */
1.266     brouard  2775:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2776:     /*           printf("%f ",pmmij[i][j]); */
                   2777:     /*         } */
                   2778:     /*         printf("\n"); */
                   2779:     /*   } */
                   2780:     /* } */
1.217     brouard  2781:     savm=oldm;
                   2782:     oldm=newm;
1.266     brouard  2783: 
1.217     brouard  2784:     for(j=1; j<=nlstate; j++){
                   2785:       max[j]=0.;
                   2786:       min[j]=1.;
                   2787:     }
                   2788:     for(j=1; j<=nlstate; j++){ 
                   2789:       for(i=1;i<=nlstate;i++){
1.234     brouard  2790:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2791:        bprlim[i][j]= newm[i][j];
                   2792:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2793:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2794:       }
                   2795:     }
1.218     brouard  2796:                
1.217     brouard  2797:     maxmax=0.;
                   2798:     for(i=1; i<=nlstate; i++){
                   2799:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2800:       maxmax=FMAX(maxmax,meandiff[i]);
                   2801:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2802:     } /* i loop */
1.217     brouard  2803:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2804:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2805:     if(maxmax < ftolpl){
1.220     brouard  2806:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2807:       free_vector(min,1,nlstate);
                   2808:       free_vector(max,1,nlstate);
                   2809:       free_vector(meandiff,1,nlstate);
                   2810:       return bprlim;
                   2811:     }
                   2812:   } /* age loop */
                   2813:     /* After some age loop it doesn't converge */
1.247     brouard  2814:   if(first){
                   2815:     first=1;
                   2816:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2817: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2818:   }
                   2819:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2820: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2821:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2822:   free_vector(min,1,nlstate);
                   2823:   free_vector(max,1,nlstate);
                   2824:   free_vector(meandiff,1,nlstate);
                   2825:   
                   2826:   return bprlim; /* should not reach here */
                   2827: }
                   2828: 
1.126     brouard  2829: /*************** transition probabilities ***************/ 
                   2830: 
                   2831: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2832: {
1.138     brouard  2833:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2834:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2835:      model to the ncovmodel covariates (including constant and age).
                   2836:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2837:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2838:      ncth covariate in the global vector x is given by the formula:
                   2839:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2840:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2841:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2842:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2843:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2844:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2845:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2846:   */
                   2847:   double s1, lnpijopii;
1.126     brouard  2848:   /*double t34;*/
1.164     brouard  2849:   int i,j, nc, ii, jj;
1.126     brouard  2850: 
1.223     brouard  2851:   for(i=1; i<= nlstate; i++){
                   2852:     for(j=1; j<i;j++){
                   2853:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2854:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2855:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2856:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2857:       }
                   2858:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2859:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2860:     }
                   2861:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2862:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2863:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2864:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2865:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2866:       }
                   2867:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2868:     }
                   2869:   }
1.218     brouard  2870:   
1.223     brouard  2871:   for(i=1; i<= nlstate; i++){
                   2872:     s1=0;
                   2873:     for(j=1; j<i; j++){
                   2874:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2875:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2876:     }
                   2877:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2878:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2879:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2880:     }
                   2881:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2882:     ps[i][i]=1./(s1+1.);
                   2883:     /* Computing other pijs */
                   2884:     for(j=1; j<i; j++)
                   2885:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2886:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2887:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2888:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2889:   } /* end i */
1.218     brouard  2890:   
1.223     brouard  2891:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2892:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2893:       ps[ii][jj]=0;
                   2894:       ps[ii][ii]=1;
                   2895:     }
                   2896:   }
1.218     brouard  2897:   
                   2898:   
1.223     brouard  2899:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2900:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2901:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2902:   /*   } */
                   2903:   /*   printf("\n "); */
                   2904:   /* } */
                   2905:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2906:   /*
                   2907:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2908:                goto end;*/
1.266     brouard  2909:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2910: }
                   2911: 
1.218     brouard  2912: /*************** backward transition probabilities ***************/ 
                   2913: 
                   2914:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2915: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2916:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2917: {
1.266     brouard  2918:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2919:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2920:    */
1.218     brouard  2921:   int i, ii, j,k;
1.222     brouard  2922:   
                   2923:   double **out, **pmij();
                   2924:   double sumnew=0.;
1.218     brouard  2925:   double agefin;
1.268     brouard  2926:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2927:   double **dnewm, **dsavm, **doldm;
                   2928:   double **bbmij;
                   2929:   
1.218     brouard  2930:   doldm=ddoldms; /* global pointers */
1.222     brouard  2931:   dnewm=ddnewms;
                   2932:   dsavm=ddsavms;
                   2933:   
                   2934:   agefin=cov[2];
1.268     brouard  2935:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2936:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2937:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2938:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2939: 
                   2940:   /* P_x */
1.266     brouard  2941:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2942:   /* outputs pmmij which is a stochastic matrix in row */
                   2943: 
                   2944:   /* Diag(w_x) */
                   2945:   /* Problem with prevacurrent which can be zero */
                   2946:   sumnew=0.;
1.269     brouard  2947:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2948:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2949:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2950:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2951:   }
                   2952:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2953:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2954:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2955:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2956:     }
                   2957:   }else{
                   2958:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2959:       for (j=1;j<=nlstate+ndeath;j++)
                   2960:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2961:     }
                   2962:     /* if(sumnew <0.9){ */
                   2963:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2964:     /* } */
                   2965:   }
                   2966:   k3=0.0;  /* We put the last diagonal to 0 */
                   2967:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2968:       doldm[ii][ii]= k3;
                   2969:   }
                   2970:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2971:   
                   2972:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2973:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2974: 
                   2975:   /* Diag(Sum_i w^i_x p^ij_x */
                   2976:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2977:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2978:     sumnew=0.;
1.222     brouard  2979:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2980:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2981:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2982:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2983:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2984:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2985:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2986:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2987:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2988:        /* }else */
1.268     brouard  2989:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2990:     } /*End ii */
                   2991:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2992: 
                   2993:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2994:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2995:   /* end bmij */
1.266     brouard  2996:   return ps; /*pointer is unchanged */
1.218     brouard  2997: }
1.217     brouard  2998: /*************** transition probabilities ***************/ 
                   2999: 
1.218     brouard  3000: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3001: {
                   3002:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3003:      computes the probability to be observed in state j being in state i by appying the
                   3004:      model to the ncovmodel covariates (including constant and age).
                   3005:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3006:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3007:      ncth covariate in the global vector x is given by the formula:
                   3008:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3009:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3010:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3011:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3012:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3013:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3014:   */
                   3015:   double s1, lnpijopii;
                   3016:   /*double t34;*/
                   3017:   int i,j, nc, ii, jj;
                   3018: 
1.234     brouard  3019:   for(i=1; i<= nlstate; i++){
                   3020:     for(j=1; j<i;j++){
                   3021:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3022:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3023:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3024:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3025:       }
                   3026:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3027:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3028:     }
                   3029:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3030:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3031:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3032:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3033:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3034:       }
                   3035:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3036:     }
                   3037:   }
                   3038:   
                   3039:   for(i=1; i<= nlstate; i++){
                   3040:     s1=0;
                   3041:     for(j=1; j<i; j++){
                   3042:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3043:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3044:     }
                   3045:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3046:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3047:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3048:     }
                   3049:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3050:     ps[i][i]=1./(s1+1.);
                   3051:     /* Computing other pijs */
                   3052:     for(j=1; j<i; j++)
                   3053:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3054:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3055:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3056:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3057:   } /* end i */
                   3058:   
                   3059:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3060:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3061:       ps[ii][jj]=0;
                   3062:       ps[ii][ii]=1;
                   3063:     }
                   3064:   }
                   3065:   /* Added for backcast */ /* Transposed matrix too */
                   3066:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3067:     s1=0.;
                   3068:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3069:       s1+=ps[ii][jj];
                   3070:     }
                   3071:     for(ii=1; ii<= nlstate; ii++){
                   3072:       ps[ii][jj]=ps[ii][jj]/s1;
                   3073:     }
                   3074:   }
                   3075:   /* Transposition */
                   3076:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3077:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3078:       s1=ps[ii][jj];
                   3079:       ps[ii][jj]=ps[jj][ii];
                   3080:       ps[jj][ii]=s1;
                   3081:     }
                   3082:   }
                   3083:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3084:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3085:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3086:   /*   } */
                   3087:   /*   printf("\n "); */
                   3088:   /* } */
                   3089:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3090:   /*
                   3091:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3092:     goto end;*/
                   3093:   return ps;
1.217     brouard  3094: }
                   3095: 
                   3096: 
1.126     brouard  3097: /**************** Product of 2 matrices ******************/
                   3098: 
1.145     brouard  3099: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3100: {
                   3101:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3102:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3103:   /* in, b, out are matrice of pointers which should have been initialized 
                   3104:      before: only the contents of out is modified. The function returns
                   3105:      a pointer to pointers identical to out */
1.145     brouard  3106:   int i, j, k;
1.126     brouard  3107:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3108:     for(k=ncolol; k<=ncoloh; k++){
                   3109:       out[i][k]=0.;
                   3110:       for(j=ncl; j<=nch; j++)
                   3111:        out[i][k] +=in[i][j]*b[j][k];
                   3112:     }
1.126     brouard  3113:   return out;
                   3114: }
                   3115: 
                   3116: 
                   3117: /************* Higher Matrix Product ***************/
                   3118: 
1.235     brouard  3119: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3120: {
1.218     brouard  3121:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3122:      'nhstepm*hstepm*stepm' months (i.e. until
                   3123:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3124:      nhstepm*hstepm matrices. 
                   3125:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3126:      (typically every 2 years instead of every month which is too big 
                   3127:      for the memory).
                   3128:      Model is determined by parameters x and covariates have to be 
                   3129:      included manually here. 
                   3130: 
                   3131:      */
                   3132: 
                   3133:   int i, j, d, h, k;
1.131     brouard  3134:   double **out, cov[NCOVMAX+1];
1.126     brouard  3135:   double **newm;
1.187     brouard  3136:   double agexact;
1.214     brouard  3137:   double agebegin, ageend;
1.126     brouard  3138: 
                   3139:   /* Hstepm could be zero and should return the unit matrix */
                   3140:   for (i=1;i<=nlstate+ndeath;i++)
                   3141:     for (j=1;j<=nlstate+ndeath;j++){
                   3142:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3143:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3144:     }
                   3145:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3146:   for(h=1; h <=nhstepm; h++){
                   3147:     for(d=1; d <=hstepm; d++){
                   3148:       newm=savm;
                   3149:       /* Covariates have to be included here again */
                   3150:       cov[1]=1.;
1.214     brouard  3151:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3152:       cov[2]=agexact;
                   3153:       if(nagesqr==1)
1.227     brouard  3154:        cov[3]= agexact*agexact;
1.235     brouard  3155:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3156:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3157:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3158:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3159:       }
                   3160:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3161:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3162:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3163:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3164:       }
                   3165:       for (k=1; k<=cptcovage;k++){
                   3166:        if(Dummy[Tvar[Tage[k]]]){
                   3167:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3168:        } else{
                   3169:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3170:        }
                   3171:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3172:       }
                   3173:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3174:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3175:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3176:       }
                   3177:       /* for (k=1; k<=cptcovn;k++)  */
                   3178:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3179:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3180:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3181:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3182:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3183:       
                   3184:       
1.126     brouard  3185:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3186:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3187:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3188:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3189:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3190:       /* if((int)age == 70){ */
                   3191:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3192:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3193:       /*         printf("%d pmmij ",i); */
                   3194:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3195:       /*           printf("%f ",pmmij[i][j]); */
                   3196:       /*         } */
                   3197:       /*         printf(" oldm "); */
                   3198:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3199:       /*           printf("%f ",oldm[i][j]); */
                   3200:       /*         } */
                   3201:       /*         printf("\n"); */
                   3202:       /*       } */
                   3203:       /* } */
1.126     brouard  3204:       savm=oldm;
                   3205:       oldm=newm;
                   3206:     }
                   3207:     for(i=1; i<=nlstate+ndeath; i++)
                   3208:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3209:        po[i][j][h]=newm[i][j];
                   3210:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3211:       }
1.128     brouard  3212:     /*printf("h=%d ",h);*/
1.126     brouard  3213:   } /* end h */
1.267     brouard  3214:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3215:   return po;
                   3216: }
                   3217: 
1.217     brouard  3218: /************* Higher Back Matrix Product ***************/
1.218     brouard  3219: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3220: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3221: {
1.266     brouard  3222:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3223:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3224:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3225:      nhstepm*hstepm matrices.
                   3226:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3227:      (typically every 2 years instead of every month which is too big
1.217     brouard  3228:      for the memory).
1.218     brouard  3229:      Model is determined by parameters x and covariates have to be
1.266     brouard  3230:      included manually here. Then we use a call to bmij(x and cov)
                   3231:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3232:   */
1.217     brouard  3233: 
                   3234:   int i, j, d, h, k;
1.266     brouard  3235:   double **out, cov[NCOVMAX+1], **bmij();
                   3236:   double **newm, ***newmm;
1.217     brouard  3237:   double agexact;
                   3238:   double agebegin, ageend;
1.222     brouard  3239:   double **oldm, **savm;
1.217     brouard  3240: 
1.266     brouard  3241:   newmm=po; /* To be saved */
                   3242:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3243:   /* Hstepm could be zero and should return the unit matrix */
                   3244:   for (i=1;i<=nlstate+ndeath;i++)
                   3245:     for (j=1;j<=nlstate+ndeath;j++){
                   3246:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3247:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3248:     }
                   3249:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3250:   for(h=1; h <=nhstepm; h++){
                   3251:     for(d=1; d <=hstepm; d++){
                   3252:       newm=savm;
                   3253:       /* Covariates have to be included here again */
                   3254:       cov[1]=1.;
1.271     brouard  3255:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3256:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3257:       cov[2]=agexact;
                   3258:       if(nagesqr==1)
1.222     brouard  3259:        cov[3]= agexact*agexact;
1.266     brouard  3260:       for (k=1; k<=cptcovn;k++){
                   3261:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3262:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3263:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3264:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3265:       }
1.267     brouard  3266:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3267:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3268:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3269:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3270:       }
                   3271:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3272:        if(Dummy[Tvar[Tage[k]]]){
                   3273:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3274:        } else{
                   3275:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3276:        }
                   3277:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3278:       }
                   3279:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3280:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3281:       }                        
1.217     brouard  3282:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3283:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3284: 
1.218     brouard  3285:       /* Careful transposed matrix */
1.266     brouard  3286:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3287:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3288:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3289:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3290:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3291:       /* if((int)age == 70){ */
                   3292:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3293:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3294:       /*         printf("%d pmmij ",i); */
                   3295:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3296:       /*           printf("%f ",pmmij[i][j]); */
                   3297:       /*         } */
                   3298:       /*         printf(" oldm "); */
                   3299:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3300:       /*           printf("%f ",oldm[i][j]); */
                   3301:       /*         } */
                   3302:       /*         printf("\n"); */
                   3303:       /*       } */
                   3304:       /* } */
                   3305:       savm=oldm;
                   3306:       oldm=newm;
                   3307:     }
                   3308:     for(i=1; i<=nlstate+ndeath; i++)
                   3309:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3310:        po[i][j][h]=newm[i][j];
1.268     brouard  3311:        /* if(h==nhstepm) */
                   3312:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3313:       }
1.268     brouard  3314:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3315:   } /* end h */
1.268     brouard  3316:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3317:   return po;
                   3318: }
                   3319: 
                   3320: 
1.162     brouard  3321: #ifdef NLOPT
                   3322:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3323:   double fret;
                   3324:   double *xt;
                   3325:   int j;
                   3326:   myfunc_data *d2 = (myfunc_data *) pd;
                   3327: /* xt = (p1-1); */
                   3328:   xt=vector(1,n); 
                   3329:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3330: 
                   3331:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3332:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3333:   printf("Function = %.12lf ",fret);
                   3334:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3335:   printf("\n");
                   3336:  free_vector(xt,1,n);
                   3337:   return fret;
                   3338: }
                   3339: #endif
1.126     brouard  3340: 
                   3341: /*************** log-likelihood *************/
                   3342: double func( double *x)
                   3343: {
1.226     brouard  3344:   int i, ii, j, k, mi, d, kk;
                   3345:   int ioffset=0;
                   3346:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3347:   double **out;
                   3348:   double lli; /* Individual log likelihood */
                   3349:   int s1, s2;
1.228     brouard  3350:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3351:   double bbh, survp;
                   3352:   long ipmx;
                   3353:   double agexact;
                   3354:   /*extern weight */
                   3355:   /* We are differentiating ll according to initial status */
                   3356:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3357:   /*for(i=1;i<imx;i++) 
                   3358:     printf(" %d\n",s[4][i]);
                   3359:   */
1.162     brouard  3360: 
1.226     brouard  3361:   ++countcallfunc;
1.162     brouard  3362: 
1.226     brouard  3363:   cov[1]=1.;
1.126     brouard  3364: 
1.226     brouard  3365:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3366:   ioffset=0;
1.226     brouard  3367:   if(mle==1){
                   3368:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3369:       /* Computes the values of the ncovmodel covariates of the model
                   3370:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3371:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3372:         to be observed in j being in i according to the model.
                   3373:       */
1.243     brouard  3374:       ioffset=2+nagesqr ;
1.233     brouard  3375:    /* Fixed */
1.234     brouard  3376:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3377:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3378:       }
1.226     brouard  3379:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3380:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3381:         has been calculated etc */
                   3382:       /* For an individual i, wav[i] gives the number of effective waves */
                   3383:       /* We compute the contribution to Likelihood of each effective transition
                   3384:         mw[mi][i] is real wave of the mi th effectve wave */
                   3385:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3386:         s2=s[mw[mi+1][i]][i];
                   3387:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3388:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3389:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3390:       */
                   3391:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3392:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3393:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3394:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3395:        }
                   3396:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3397:          for (j=1;j<=nlstate+ndeath;j++){
                   3398:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3399:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3400:          }
                   3401:        for(d=0; d<dh[mi][i]; d++){
                   3402:          newm=savm;
                   3403:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3404:          cov[2]=agexact;
                   3405:          if(nagesqr==1)
                   3406:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3407:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3408:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3409:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3410:          else
                   3411:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3412:          }
                   3413:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3414:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3415:          savm=oldm;
                   3416:          oldm=newm;
                   3417:        } /* end mult */
                   3418:        
                   3419:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3420:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3421:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3422:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3423:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3424:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3425:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3426:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3427:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3428:                                 * -stepm/2 to stepm/2 .
                   3429:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3430:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3431:                                 */
1.234     brouard  3432:        s1=s[mw[mi][i]][i];
                   3433:        s2=s[mw[mi+1][i]][i];
                   3434:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3435:        /* bias bh is positive if real duration
                   3436:         * is higher than the multiple of stepm and negative otherwise.
                   3437:         */
                   3438:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3439:        if( s2 > nlstate){ 
                   3440:          /* i.e. if s2 is a death state and if the date of death is known 
                   3441:             then the contribution to the likelihood is the probability to 
                   3442:             die between last step unit time and current  step unit time, 
                   3443:             which is also equal to probability to die before dh 
                   3444:             minus probability to die before dh-stepm . 
                   3445:             In version up to 0.92 likelihood was computed
                   3446:             as if date of death was unknown. Death was treated as any other
                   3447:             health state: the date of the interview describes the actual state
                   3448:             and not the date of a change in health state. The former idea was
                   3449:             to consider that at each interview the state was recorded
                   3450:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3451:             introduced the exact date of death then we should have modified
                   3452:             the contribution of an exact death to the likelihood. This new
                   3453:             contribution is smaller and very dependent of the step unit
                   3454:             stepm. It is no more the probability to die between last interview
                   3455:             and month of death but the probability to survive from last
                   3456:             interview up to one month before death multiplied by the
                   3457:             probability to die within a month. Thanks to Chris
                   3458:             Jackson for correcting this bug.  Former versions increased
                   3459:             mortality artificially. The bad side is that we add another loop
                   3460:             which slows down the processing. The difference can be up to 10%
                   3461:             lower mortality.
                   3462:          */
                   3463:          /* If, at the beginning of the maximization mostly, the
                   3464:             cumulative probability or probability to be dead is
                   3465:             constant (ie = 1) over time d, the difference is equal to
                   3466:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3467:             s1 at precedent wave, to be dead a month before current
                   3468:             wave is equal to probability, being at state s1 at
                   3469:             precedent wave, to be dead at mont of the current
                   3470:             wave. Then the observed probability (that this person died)
                   3471:             is null according to current estimated parameter. In fact,
                   3472:             it should be very low but not zero otherwise the log go to
                   3473:             infinity.
                   3474:          */
1.183     brouard  3475: /* #ifdef INFINITYORIGINAL */
                   3476: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3477: /* #else */
                   3478: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3479: /*         lli=log(mytinydouble); */
                   3480: /*       else */
                   3481: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3482: /* #endif */
1.226     brouard  3483:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3484:          
1.226     brouard  3485:        } else if  ( s2==-1 ) { /* alive */
                   3486:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3487:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3488:          /*survp += out[s1][j]; */
                   3489:          lli= log(survp);
                   3490:        }
                   3491:        else if  (s2==-4) { 
                   3492:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3493:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3494:          lli= log(survp); 
                   3495:        } 
                   3496:        else if  (s2==-5) { 
                   3497:          for (j=1,survp=0. ; j<=2; j++)  
                   3498:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3499:          lli= log(survp); 
                   3500:        } 
                   3501:        else{
                   3502:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3503:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3504:        } 
                   3505:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3506:        /*if(lli ==000.0)*/
                   3507:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3508:        ipmx +=1;
                   3509:        sw += weight[i];
                   3510:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3511:        /* if (lli < log(mytinydouble)){ */
                   3512:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3513:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3514:        /* } */
                   3515:       } /* end of wave */
                   3516:     } /* end of individual */
                   3517:   }  else if(mle==2){
                   3518:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3519:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3520:       for(mi=1; mi<= wav[i]-1; mi++){
                   3521:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3522:          for (j=1;j<=nlstate+ndeath;j++){
                   3523:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3524:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3525:          }
                   3526:        for(d=0; d<=dh[mi][i]; d++){
                   3527:          newm=savm;
                   3528:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3529:          cov[2]=agexact;
                   3530:          if(nagesqr==1)
                   3531:            cov[3]= agexact*agexact;
                   3532:          for (kk=1; kk<=cptcovage;kk++) {
                   3533:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3534:          }
                   3535:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3536:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3537:          savm=oldm;
                   3538:          oldm=newm;
                   3539:        } /* end mult */
                   3540:       
                   3541:        s1=s[mw[mi][i]][i];
                   3542:        s2=s[mw[mi+1][i]][i];
                   3543:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3544:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3545:        ipmx +=1;
                   3546:        sw += weight[i];
                   3547:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3548:       } /* end of wave */
                   3549:     } /* end of individual */
                   3550:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3551:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3552:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3553:       for(mi=1; mi<= wav[i]-1; mi++){
                   3554:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3555:          for (j=1;j<=nlstate+ndeath;j++){
                   3556:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3557:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3558:          }
                   3559:        for(d=0; d<dh[mi][i]; d++){
                   3560:          newm=savm;
                   3561:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3562:          cov[2]=agexact;
                   3563:          if(nagesqr==1)
                   3564:            cov[3]= agexact*agexact;
                   3565:          for (kk=1; kk<=cptcovage;kk++) {
                   3566:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3567:          }
                   3568:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3569:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3570:          savm=oldm;
                   3571:          oldm=newm;
                   3572:        } /* end mult */
                   3573:       
                   3574:        s1=s[mw[mi][i]][i];
                   3575:        s2=s[mw[mi+1][i]][i];
                   3576:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3577:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3578:        ipmx +=1;
                   3579:        sw += weight[i];
                   3580:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3581:       } /* end of wave */
                   3582:     } /* end of individual */
                   3583:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3584:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3585:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3586:       for(mi=1; mi<= wav[i]-1; mi++){
                   3587:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3588:          for (j=1;j<=nlstate+ndeath;j++){
                   3589:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3590:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3591:          }
                   3592:        for(d=0; d<dh[mi][i]; d++){
                   3593:          newm=savm;
                   3594:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3595:          cov[2]=agexact;
                   3596:          if(nagesqr==1)
                   3597:            cov[3]= agexact*agexact;
                   3598:          for (kk=1; kk<=cptcovage;kk++) {
                   3599:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3600:          }
1.126     brouard  3601:        
1.226     brouard  3602:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3603:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3604:          savm=oldm;
                   3605:          oldm=newm;
                   3606:        } /* end mult */
                   3607:       
                   3608:        s1=s[mw[mi][i]][i];
                   3609:        s2=s[mw[mi+1][i]][i];
                   3610:        if( s2 > nlstate){ 
                   3611:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3612:        } else if  ( s2==-1 ) { /* alive */
                   3613:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3614:            survp += out[s1][j];
                   3615:          lli= log(survp);
                   3616:        }else{
                   3617:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3618:        }
                   3619:        ipmx +=1;
                   3620:        sw += weight[i];
                   3621:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3622: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3623:       } /* end of wave */
                   3624:     } /* end of individual */
                   3625:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3626:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3627:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3628:       for(mi=1; mi<= wav[i]-1; mi++){
                   3629:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3630:          for (j=1;j<=nlstate+ndeath;j++){
                   3631:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3632:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3633:          }
                   3634:        for(d=0; d<dh[mi][i]; d++){
                   3635:          newm=savm;
                   3636:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3637:          cov[2]=agexact;
                   3638:          if(nagesqr==1)
                   3639:            cov[3]= agexact*agexact;
                   3640:          for (kk=1; kk<=cptcovage;kk++) {
                   3641:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3642:          }
1.126     brouard  3643:        
1.226     brouard  3644:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3645:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3646:          savm=oldm;
                   3647:          oldm=newm;
                   3648:        } /* end mult */
                   3649:       
                   3650:        s1=s[mw[mi][i]][i];
                   3651:        s2=s[mw[mi+1][i]][i];
                   3652:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3653:        ipmx +=1;
                   3654:        sw += weight[i];
                   3655:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3656:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3657:       } /* end of wave */
                   3658:     } /* end of individual */
                   3659:   } /* End of if */
                   3660:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3661:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3662:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3663:   return -l;
1.126     brouard  3664: }
                   3665: 
                   3666: /*************** log-likelihood *************/
                   3667: double funcone( double *x)
                   3668: {
1.228     brouard  3669:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3670:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3671:   int ioffset=0;
1.131     brouard  3672:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3673:   double **out;
                   3674:   double lli; /* Individual log likelihood */
                   3675:   double llt;
                   3676:   int s1, s2;
1.228     brouard  3677:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3678: 
1.126     brouard  3679:   double bbh, survp;
1.187     brouard  3680:   double agexact;
1.214     brouard  3681:   double agebegin, ageend;
1.126     brouard  3682:   /*extern weight */
                   3683:   /* We are differentiating ll according to initial status */
                   3684:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3685:   /*for(i=1;i<imx;i++) 
                   3686:     printf(" %d\n",s[4][i]);
                   3687:   */
                   3688:   cov[1]=1.;
                   3689: 
                   3690:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3691:   ioffset=0;
                   3692:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3693:     /* ioffset=2+nagesqr+cptcovage; */
                   3694:     ioffset=2+nagesqr;
1.232     brouard  3695:     /* Fixed */
1.224     brouard  3696:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3697:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3698:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3699:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3700: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3701: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3702: /*    cov[2+6]=covar[2][i]; V2  */
                   3703: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3704: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3705: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3706: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3707: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3708: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3709:     }
1.232     brouard  3710:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3711:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3712:     /* } */
1.231     brouard  3713:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3714:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3715:     /* } */
1.225     brouard  3716:     
1.233     brouard  3717: 
                   3718:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3719:     /* Wave varying (but not age varying) */
                   3720:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3721:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3722:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3723:       }
1.232     brouard  3724:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3725:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3726:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3727:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3728:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3729:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3730:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3731:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3732:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3733:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3734:       /* } */
1.126     brouard  3735:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3736:        for (j=1;j<=nlstate+ndeath;j++){
                   3737:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3738:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3739:        }
1.214     brouard  3740:       
                   3741:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3742:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3743:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3744:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3745:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3746:          and mw[mi+1][i]. dh depends on stepm.*/
                   3747:        newm=savm;
1.247     brouard  3748:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3749:        cov[2]=agexact;
                   3750:        if(nagesqr==1)
                   3751:          cov[3]= agexact*agexact;
                   3752:        for (kk=1; kk<=cptcovage;kk++) {
                   3753:          if(!FixedV[Tvar[Tage[kk]]])
                   3754:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3755:          else
                   3756:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3757:        }
                   3758:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3759:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3760:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3761:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3762:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3763:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3764:        savm=oldm;
                   3765:        oldm=newm;
1.126     brouard  3766:       } /* end mult */
                   3767:       
                   3768:       s1=s[mw[mi][i]][i];
                   3769:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3770:       /* if(s2==-1){ */
1.268     brouard  3771:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3772:       /*       /\* exit(1); *\/ */
                   3773:       /* } */
1.126     brouard  3774:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3775:       /* bias is positive if real duration
                   3776:        * is higher than the multiple of stepm and negative otherwise.
                   3777:        */
                   3778:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3779:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3780:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3781:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3782:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3783:        lli= log(survp);
1.126     brouard  3784:       }else if (mle==1){
1.242     brouard  3785:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3786:       } else if(mle==2){
1.242     brouard  3787:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3788:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3789:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3790:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3791:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3792:       } else{  /* mle=0 back to 1 */
1.242     brouard  3793:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3794:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3795:       } /* End of if */
                   3796:       ipmx +=1;
                   3797:       sw += weight[i];
                   3798:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3799:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3800:       if(globpr){
1.246     brouard  3801:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3802:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3803:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3804:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3805:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3806:          llt +=ll[k]*gipmx/gsw;
                   3807:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3808:        }
                   3809:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3810:       }
1.232     brouard  3811:        } /* end of wave */
                   3812: } /* end of individual */
                   3813: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3814: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3815: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3816: if(globpr==0){ /* First time we count the contributions and weights */
                   3817:        gipmx=ipmx;
                   3818:        gsw=sw;
                   3819: }
                   3820: return -l;
1.126     brouard  3821: }
                   3822: 
                   3823: 
                   3824: /*************** function likelione ***********/
                   3825: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3826: {
                   3827:   /* This routine should help understanding what is done with 
                   3828:      the selection of individuals/waves and
                   3829:      to check the exact contribution to the likelihood.
                   3830:      Plotting could be done.
                   3831:    */
                   3832:   int k;
                   3833: 
                   3834:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3835:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3836:     strcat(fileresilk,fileresu);
1.126     brouard  3837:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3838:       printf("Problem with resultfile: %s\n", fileresilk);
                   3839:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3840:     }
1.214     brouard  3841:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3842:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3843:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3844:     for(k=1; k<=nlstate; k++) 
                   3845:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3846:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3847:   }
                   3848: 
                   3849:   *fretone=(*funcone)(p);
                   3850:   if(*globpri !=0){
                   3851:     fclose(ficresilk);
1.205     brouard  3852:     if (mle ==0)
                   3853:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3854:     else if(mle >=1)
                   3855:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3856:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274   ! brouard  3857:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3858:       
                   3859:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3860:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3861: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3862:     }
1.207     brouard  3863:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3864: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3865:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3866: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3867:     fflush(fichtm);
1.205     brouard  3868:   }
1.126     brouard  3869:   return;
                   3870: }
                   3871: 
                   3872: 
                   3873: /*********** Maximum Likelihood Estimation ***************/
                   3874: 
                   3875: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3876: {
1.165     brouard  3877:   int i,j, iter=0;
1.126     brouard  3878:   double **xi;
                   3879:   double fret;
                   3880:   double fretone; /* Only one call to likelihood */
                   3881:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3882: 
                   3883: #ifdef NLOPT
                   3884:   int creturn;
                   3885:   nlopt_opt opt;
                   3886:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3887:   double *lb;
                   3888:   double minf; /* the minimum objective value, upon return */
                   3889:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3890:   myfunc_data dinst, *d = &dinst;
                   3891: #endif
                   3892: 
                   3893: 
1.126     brouard  3894:   xi=matrix(1,npar,1,npar);
                   3895:   for (i=1;i<=npar;i++)
                   3896:     for (j=1;j<=npar;j++)
                   3897:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3898:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3899:   strcpy(filerespow,"POW_"); 
1.126     brouard  3900:   strcat(filerespow,fileres);
                   3901:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3902:     printf("Problem with resultfile: %s\n", filerespow);
                   3903:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3904:   }
                   3905:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3906:   for (i=1;i<=nlstate;i++)
                   3907:     for(j=1;j<=nlstate+ndeath;j++)
                   3908:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3909:   fprintf(ficrespow,"\n");
1.162     brouard  3910: #ifdef POWELL
1.126     brouard  3911:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3912: #endif
1.126     brouard  3913: 
1.162     brouard  3914: #ifdef NLOPT
                   3915: #ifdef NEWUOA
                   3916:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3917: #else
                   3918:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3919: #endif
                   3920:   lb=vector(0,npar-1);
                   3921:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3922:   nlopt_set_lower_bounds(opt, lb);
                   3923:   nlopt_set_initial_step1(opt, 0.1);
                   3924:   
                   3925:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3926:   d->function = func;
                   3927:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3928:   nlopt_set_min_objective(opt, myfunc, d);
                   3929:   nlopt_set_xtol_rel(opt, ftol);
                   3930:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3931:     printf("nlopt failed! %d\n",creturn); 
                   3932:   }
                   3933:   else {
                   3934:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3935:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3936:     iter=1; /* not equal */
                   3937:   }
                   3938:   nlopt_destroy(opt);
                   3939: #endif
1.126     brouard  3940:   free_matrix(xi,1,npar,1,npar);
                   3941:   fclose(ficrespow);
1.203     brouard  3942:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3943:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3944:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3945: 
                   3946: }
                   3947: 
                   3948: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3949: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3950: {
                   3951:   double  **a,**y,*x,pd;
1.203     brouard  3952:   /* double **hess; */
1.164     brouard  3953:   int i, j;
1.126     brouard  3954:   int *indx;
                   3955: 
                   3956:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3957:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3958:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3959:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3960:   double gompertz(double p[]);
1.203     brouard  3961:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3962: 
                   3963:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3964:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3965:   for (i=1;i<=npar;i++){
1.203     brouard  3966:     printf("%d-",i);fflush(stdout);
                   3967:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3968:    
                   3969:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3970:     
                   3971:     /*  printf(" %f ",p[i]);
                   3972:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3973:   }
                   3974:   
                   3975:   for (i=1;i<=npar;i++) {
                   3976:     for (j=1;j<=npar;j++)  {
                   3977:       if (j>i) { 
1.203     brouard  3978:        printf(".%d-%d",i,j);fflush(stdout);
                   3979:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3980:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3981:        
                   3982:        hess[j][i]=hess[i][j];    
                   3983:        /*printf(" %lf ",hess[i][j]);*/
                   3984:       }
                   3985:     }
                   3986:   }
                   3987:   printf("\n");
                   3988:   fprintf(ficlog,"\n");
                   3989: 
                   3990:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3991:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3992:   
                   3993:   a=matrix(1,npar,1,npar);
                   3994:   y=matrix(1,npar,1,npar);
                   3995:   x=vector(1,npar);
                   3996:   indx=ivector(1,npar);
                   3997:   for (i=1;i<=npar;i++)
                   3998:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3999:   ludcmp(a,npar,indx,&pd);
                   4000: 
                   4001:   for (j=1;j<=npar;j++) {
                   4002:     for (i=1;i<=npar;i++) x[i]=0;
                   4003:     x[j]=1;
                   4004:     lubksb(a,npar,indx,x);
                   4005:     for (i=1;i<=npar;i++){ 
                   4006:       matcov[i][j]=x[i];
                   4007:     }
                   4008:   }
                   4009: 
                   4010:   printf("\n#Hessian matrix#\n");
                   4011:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4012:   for (i=1;i<=npar;i++) { 
                   4013:     for (j=1;j<=npar;j++) { 
1.203     brouard  4014:       printf("%.6e ",hess[i][j]);
                   4015:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4016:     }
                   4017:     printf("\n");
                   4018:     fprintf(ficlog,"\n");
                   4019:   }
                   4020: 
1.203     brouard  4021:   /* printf("\n#Covariance matrix#\n"); */
                   4022:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4023:   /* for (i=1;i<=npar;i++) {  */
                   4024:   /*   for (j=1;j<=npar;j++) {  */
                   4025:   /*     printf("%.6e ",matcov[i][j]); */
                   4026:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4027:   /*   } */
                   4028:   /*   printf("\n"); */
                   4029:   /*   fprintf(ficlog,"\n"); */
                   4030:   /* } */
                   4031: 
1.126     brouard  4032:   /* Recompute Inverse */
1.203     brouard  4033:   /* for (i=1;i<=npar;i++) */
                   4034:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4035:   /* ludcmp(a,npar,indx,&pd); */
                   4036: 
                   4037:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4038: 
                   4039:   /* for (j=1;j<=npar;j++) { */
                   4040:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4041:   /*   x[j]=1; */
                   4042:   /*   lubksb(a,npar,indx,x); */
                   4043:   /*   for (i=1;i<=npar;i++){  */
                   4044:   /*     y[i][j]=x[i]; */
                   4045:   /*     printf("%.3e ",y[i][j]); */
                   4046:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4047:   /*   } */
                   4048:   /*   printf("\n"); */
                   4049:   /*   fprintf(ficlog,"\n"); */
                   4050:   /* } */
                   4051: 
                   4052:   /* Verifying the inverse matrix */
                   4053: #ifdef DEBUGHESS
                   4054:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4055: 
1.203     brouard  4056:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4057:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4058: 
                   4059:   for (j=1;j<=npar;j++) {
                   4060:     for (i=1;i<=npar;i++){ 
1.203     brouard  4061:       printf("%.2f ",y[i][j]);
                   4062:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4063:     }
                   4064:     printf("\n");
                   4065:     fprintf(ficlog,"\n");
                   4066:   }
1.203     brouard  4067: #endif
1.126     brouard  4068: 
                   4069:   free_matrix(a,1,npar,1,npar);
                   4070:   free_matrix(y,1,npar,1,npar);
                   4071:   free_vector(x,1,npar);
                   4072:   free_ivector(indx,1,npar);
1.203     brouard  4073:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4074: 
                   4075: 
                   4076: }
                   4077: 
                   4078: /*************** hessian matrix ****************/
                   4079: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4080: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4081:   int i;
                   4082:   int l=1, lmax=20;
1.203     brouard  4083:   double k1,k2, res, fx;
1.132     brouard  4084:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4085:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4086:   int k=0,kmax=10;
                   4087:   double l1;
                   4088: 
                   4089:   fx=func(x);
                   4090:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4091:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4092:     l1=pow(10,l);
                   4093:     delts=delt;
                   4094:     for(k=1 ; k <kmax; k=k+1){
                   4095:       delt = delta*(l1*k);
                   4096:       p2[theta]=x[theta] +delt;
1.145     brouard  4097:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4098:       p2[theta]=x[theta]-delt;
                   4099:       k2=func(p2)-fx;
                   4100:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4101:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4102:       
1.203     brouard  4103: #ifdef DEBUGHESSII
1.126     brouard  4104:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4105:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4106: #endif
                   4107:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4108:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4109:        k=kmax;
                   4110:       }
                   4111:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4112:        k=kmax; l=lmax*10;
1.126     brouard  4113:       }
                   4114:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4115:        delts=delt;
                   4116:       }
1.203     brouard  4117:     } /* End loop k */
1.126     brouard  4118:   }
                   4119:   delti[theta]=delts;
                   4120:   return res; 
                   4121:   
                   4122: }
                   4123: 
1.203     brouard  4124: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4125: {
                   4126:   int i;
1.164     brouard  4127:   int l=1, lmax=20;
1.126     brouard  4128:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4129:   double p2[MAXPARM+1];
1.203     brouard  4130:   int k, kmax=1;
                   4131:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4132: 
                   4133:   int firstime=0;
1.203     brouard  4134:   
1.126     brouard  4135:   fx=func(x);
1.203     brouard  4136:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4137:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4138:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4139:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4140:     k1=func(p2)-fx;
                   4141:   
1.203     brouard  4142:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4143:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4144:     k2=func(p2)-fx;
                   4145:   
1.203     brouard  4146:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4147:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4148:     k3=func(p2)-fx;
                   4149:   
1.203     brouard  4150:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4151:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4152:     k4=func(p2)-fx;
1.203     brouard  4153:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4154:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4155:       firstime=1;
1.203     brouard  4156:       kmax=kmax+10;
1.208     brouard  4157:     }
                   4158:     if(kmax >=10 || firstime ==1){
1.246     brouard  4159:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4160:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4161:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4162:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4163:     }
                   4164: #ifdef DEBUGHESSIJ
                   4165:     v1=hess[thetai][thetai];
                   4166:     v2=hess[thetaj][thetaj];
                   4167:     cv12=res;
                   4168:     /* Computing eigen value of Hessian matrix */
                   4169:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4170:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4171:     if ((lc2 <0) || (lc1 <0) ){
                   4172:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4173:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4174:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4175:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4176:     }
1.126     brouard  4177: #endif
                   4178:   }
                   4179:   return res;
                   4180: }
                   4181: 
1.203     brouard  4182:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4183: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4184: /* { */
                   4185: /*   int i; */
                   4186: /*   int l=1, lmax=20; */
                   4187: /*   double k1,k2,k3,k4,res,fx; */
                   4188: /*   double p2[MAXPARM+1]; */
                   4189: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4190: /*   int k=0,kmax=10; */
                   4191: /*   double l1; */
                   4192:   
                   4193: /*   fx=func(x); */
                   4194: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4195: /*     l1=pow(10,l); */
                   4196: /*     delts=delt; */
                   4197: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4198: /*       delt = delti*(l1*k); */
                   4199: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4200: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4201: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4202: /*       k1=func(p2)-fx; */
                   4203:       
                   4204: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4205: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4206: /*       k2=func(p2)-fx; */
                   4207:       
                   4208: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4209: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4210: /*       k3=func(p2)-fx; */
                   4211:       
                   4212: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4213: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4214: /*       k4=func(p2)-fx; */
                   4215: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4216: /* #ifdef DEBUGHESSIJ */
                   4217: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4218: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4219: /* #endif */
                   4220: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4221: /*     k=kmax; */
                   4222: /*       } */
                   4223: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4224: /*     k=kmax; l=lmax*10; */
                   4225: /*       } */
                   4226: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4227: /*     delts=delt; */
                   4228: /*       } */
                   4229: /*     } /\* End loop k *\/ */
                   4230: /*   } */
                   4231: /*   delti[theta]=delts; */
                   4232: /*   return res;  */
                   4233: /* } */
                   4234: 
                   4235: 
1.126     brouard  4236: /************** Inverse of matrix **************/
                   4237: void ludcmp(double **a, int n, int *indx, double *d) 
                   4238: { 
                   4239:   int i,imax,j,k; 
                   4240:   double big,dum,sum,temp; 
                   4241:   double *vv; 
                   4242:  
                   4243:   vv=vector(1,n); 
                   4244:   *d=1.0; 
                   4245:   for (i=1;i<=n;i++) { 
                   4246:     big=0.0; 
                   4247:     for (j=1;j<=n;j++) 
                   4248:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4249:     if (big == 0.0){
                   4250:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4251:       for (j=1;j<=n;j++) {
                   4252:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4253:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4254:       }
                   4255:       fflush(ficlog);
                   4256:       fclose(ficlog);
                   4257:       nrerror("Singular matrix in routine ludcmp"); 
                   4258:     }
1.126     brouard  4259:     vv[i]=1.0/big; 
                   4260:   } 
                   4261:   for (j=1;j<=n;j++) { 
                   4262:     for (i=1;i<j;i++) { 
                   4263:       sum=a[i][j]; 
                   4264:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4265:       a[i][j]=sum; 
                   4266:     } 
                   4267:     big=0.0; 
                   4268:     for (i=j;i<=n;i++) { 
                   4269:       sum=a[i][j]; 
                   4270:       for (k=1;k<j;k++) 
                   4271:        sum -= a[i][k]*a[k][j]; 
                   4272:       a[i][j]=sum; 
                   4273:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4274:        big=dum; 
                   4275:        imax=i; 
                   4276:       } 
                   4277:     } 
                   4278:     if (j != imax) { 
                   4279:       for (k=1;k<=n;k++) { 
                   4280:        dum=a[imax][k]; 
                   4281:        a[imax][k]=a[j][k]; 
                   4282:        a[j][k]=dum; 
                   4283:       } 
                   4284:       *d = -(*d); 
                   4285:       vv[imax]=vv[j]; 
                   4286:     } 
                   4287:     indx[j]=imax; 
                   4288:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4289:     if (j != n) { 
                   4290:       dum=1.0/(a[j][j]); 
                   4291:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4292:     } 
                   4293:   } 
                   4294:   free_vector(vv,1,n);  /* Doesn't work */
                   4295: ;
                   4296: } 
                   4297: 
                   4298: void lubksb(double **a, int n, int *indx, double b[]) 
                   4299: { 
                   4300:   int i,ii=0,ip,j; 
                   4301:   double sum; 
                   4302:  
                   4303:   for (i=1;i<=n;i++) { 
                   4304:     ip=indx[i]; 
                   4305:     sum=b[ip]; 
                   4306:     b[ip]=b[i]; 
                   4307:     if (ii) 
                   4308:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4309:     else if (sum) ii=i; 
                   4310:     b[i]=sum; 
                   4311:   } 
                   4312:   for (i=n;i>=1;i--) { 
                   4313:     sum=b[i]; 
                   4314:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4315:     b[i]=sum/a[i][i]; 
                   4316:   } 
                   4317: } 
                   4318: 
                   4319: void pstamp(FILE *fichier)
                   4320: {
1.196     brouard  4321:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4322: }
                   4323: 
1.253     brouard  4324: 
                   4325: 
1.126     brouard  4326: /************ Frequencies ********************/
1.251     brouard  4327: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4328:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4329:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4330: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4331:   
1.265     brouard  4332:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4333:   int iind=0, iage=0;
                   4334:   int mi; /* Effective wave */
                   4335:   int first;
                   4336:   double ***freq; /* Frequencies */
1.268     brouard  4337:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4338:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4339:   double *meanq;
                   4340:   double **meanqt;
                   4341:   double *pp, **prop, *posprop, *pospropt;
                   4342:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4343:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4344:   double agebegin, ageend;
                   4345:     
                   4346:   pp=vector(1,nlstate);
1.251     brouard  4347:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4348:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4349:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4350:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4351:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4352:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4353:   strcpy(fileresp,"P_");
                   4354:   strcat(fileresp,fileresu);
                   4355:   /*strcat(fileresphtm,fileresu);*/
                   4356:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4357:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4358:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4359:     exit(0);
                   4360:   }
1.240     brouard  4361:   
1.226     brouard  4362:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4363:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4364:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4365:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4366:     fflush(ficlog);
                   4367:     exit(70); 
                   4368:   }
                   4369:   else{
                   4370:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4371: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4372: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4373:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4374:   }
1.237     brouard  4375:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4376:   
1.226     brouard  4377:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4378:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4379:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4380:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4381:     fflush(ficlog);
                   4382:     exit(70); 
1.240     brouard  4383:   } else{
1.226     brouard  4384:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4385: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4386: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4387:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4388:   }
1.240     brouard  4389:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4390:   
1.253     brouard  4391:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4392:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4393:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4394:   j1=0;
1.126     brouard  4395:   
1.227     brouard  4396:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4397:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4398:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4399:   
                   4400:   
1.226     brouard  4401:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4402:      reference=low_education V1=0,V2=0
                   4403:      med_educ                V1=1 V2=0, 
                   4404:      high_educ               V1=0 V2=1
                   4405:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4406:   */
1.249     brouard  4407:   dateintsum=0;
                   4408:   k2cpt=0;
                   4409: 
1.253     brouard  4410:   if(cptcoveff == 0 )
1.265     brouard  4411:     nl=1;  /* Constant and age model only */
1.253     brouard  4412:   else
                   4413:     nl=2;
1.265     brouard  4414: 
                   4415:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4416:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4417:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4418:    *     freq[s1][s2][iage] =0.
                   4419:    *     Loop on iind
                   4420:    *       ++freq[s1][s2][iage] weighted
                   4421:    *     end iind
                   4422:    *     if covariate and j!0
                   4423:    *       headers Variable on one line
                   4424:    *     endif cov j!=0
                   4425:    *     header of frequency table by age
                   4426:    *     Loop on age
                   4427:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4428:    *       pos+=freq[s1][s2][iage] weighted
                   4429:    *       Loop on s1 initial state
                   4430:    *         fprintf(ficresp
                   4431:    *       end s1
                   4432:    *     end age
                   4433:    *     if j!=0 computes starting values
                   4434:    *     end compute starting values
                   4435:    *   end j1
                   4436:    * end nl 
                   4437:    */
1.253     brouard  4438:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4439:     if(nj==1)
                   4440:       j=0;  /* First pass for the constant */
1.265     brouard  4441:     else{
1.253     brouard  4442:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4443:     }
1.251     brouard  4444:     first=1;
1.265     brouard  4445:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4446:       posproptt=0.;
                   4447:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4448:        scanf("%d", i);*/
                   4449:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4450:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4451:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4452:            freq[i][s2][m]=0;
1.251     brouard  4453:       
                   4454:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4455:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4456:          prop[i][m]=0;
                   4457:        posprop[i]=0;
                   4458:        pospropt[i]=0;
                   4459:       }
                   4460:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4461:       /*   meanq[z1]+=0.; */
                   4462:       /*   for(m=1;m<=lastpass;m++){ */
                   4463:       /*       meanqt[m][z1]=0.; */
                   4464:       /*   } */
                   4465:       /* } */
                   4466:       
                   4467:       /* dateintsum=0; */
                   4468:       /* k2cpt=0; */
                   4469:       
1.265     brouard  4470:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4471:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4472:        bool=1;
                   4473:        if(j !=0){
                   4474:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4475:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4476:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4477:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4478:              /* } */
                   4479:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4480:                /* if(Tvaraff[z1] ==-20){ */
                   4481:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4482:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4483:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4484:                /* }else  */
                   4485:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4486:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4487:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4488:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4489:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4490:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4491:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4492:                } /* Onlyf fixed */
                   4493:              } /* end z1 */
                   4494:            } /* cptcovn > 0 */
                   4495:          } /* end any */
                   4496:        }/* end j==0 */
1.265     brouard  4497:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4498:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4499:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4500:            m=mw[mi][iind];
                   4501:            if(j!=0){
                   4502:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4503:                for (z1=1; z1<=cptcoveff; z1++) {
                   4504:                  if( Fixed[Tmodelind[z1]]==1){
                   4505:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4506:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4507:                                                                                      value is -1, we don't select. It differs from the 
                   4508:                                                                                      constant and age model which counts them. */
                   4509:                      bool=0; /* not selected */
                   4510:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4511:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4512:                      bool=0;
                   4513:                    }
                   4514:                  }
                   4515:                }
                   4516:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4517:            } /* end j==0 */
                   4518:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4519:            if(bool==1){
                   4520:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4521:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4522:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4523:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4524:              if(m >=firstpass && m <=lastpass){
                   4525:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4526:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4527:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4528:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4529:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4530:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4531:                if (m<lastpass) {
                   4532:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4533:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4534:                  if(s[m][iind]==-1)
                   4535:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4536:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4537:                  /* if((int)agev[m][iind] == 55) */
                   4538:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4539:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4540:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4541:                }
1.251     brouard  4542:              } /* end if between passes */  
                   4543:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4544:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4545:                k2cpt++;
                   4546:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4547:              }
1.251     brouard  4548:            }else{
                   4549:              bool=1;
                   4550:            }/* end bool 2 */
                   4551:          } /* end m */
                   4552:        } /* end bool */
                   4553:       } /* end iind = 1 to imx */
                   4554:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4555:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4556:       
                   4557:       
                   4558:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4559:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4560:         pstamp(ficresp);
1.251     brouard  4561:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4562:         pstamp(ficresp);
1.251     brouard  4563:        printf( "\n#********** Variable "); 
                   4564:        fprintf(ficresp, "\n#********** Variable "); 
                   4565:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4566:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4567:        fprintf(ficlog, "\n#********** Variable "); 
                   4568:        for (z1=1; z1<=cptcoveff; z1++){
                   4569:          if(!FixedV[Tvaraff[z1]]){
                   4570:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4571:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4572:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4573:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4574:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4575:          }else{
1.251     brouard  4576:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4577:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4578:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4579:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4580:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4581:          }
                   4582:        }
                   4583:        printf( "**********\n#");
                   4584:        fprintf(ficresp, "**********\n#");
                   4585:        fprintf(ficresphtm, "**********</h3>\n");
                   4586:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4587:        fprintf(ficlog, "**********\n");
                   4588:       }
                   4589:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4590:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4591:         fprintf(ficresp, " Age");
                   4592:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4593:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4594:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4595:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4596:       }
1.265     brouard  4597:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4598:       fprintf(ficresphtm, "\n");
                   4599:       
                   4600:       /* Header of frequency table by age */
                   4601:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4602:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4603:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4604:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4605:          if(s2!=0 && m!=0)
                   4606:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4607:        }
1.226     brouard  4608:       }
1.251     brouard  4609:       fprintf(ficresphtmfr, "\n");
                   4610:     
                   4611:       /* For each age */
                   4612:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4613:        fprintf(ficresphtm,"<tr>");
                   4614:        if(iage==iagemax+1){
                   4615:          fprintf(ficlog,"1");
                   4616:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4617:        }else if(iage==iagemax+2){
                   4618:          fprintf(ficlog,"0");
                   4619:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4620:        }else if(iage==iagemax+3){
                   4621:          fprintf(ficlog,"Total");
                   4622:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4623:        }else{
1.240     brouard  4624:          if(first==1){
1.251     brouard  4625:            first=0;
                   4626:            printf("See log file for details...\n");
                   4627:          }
                   4628:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4629:          fprintf(ficlog,"Age %d", iage);
                   4630:        }
1.265     brouard  4631:        for(s1=1; s1 <=nlstate ; s1++){
                   4632:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4633:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4634:        }
1.265     brouard  4635:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4636:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4637:            pos += freq[s1][m][iage];
                   4638:          if(pp[s1]>=1.e-10){
1.251     brouard  4639:            if(first==1){
1.265     brouard  4640:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4641:            }
1.265     brouard  4642:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4643:          }else{
                   4644:            if(first==1)
1.265     brouard  4645:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4646:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4647:          }
                   4648:        }
                   4649:       
1.265     brouard  4650:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4651:          /* posprop[s1]=0; */
                   4652:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4653:            pp[s1] += freq[s1][m][iage];
                   4654:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4655:       
                   4656:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4657:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4658:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4659:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4660:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4661:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4662:        }
                   4663:        
                   4664:        /* Writing ficresp */
                   4665:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4666:           if( iage <= iagemax){
                   4667:            fprintf(ficresp," %d",iage);
                   4668:           }
                   4669:         }else if( nj==2){
                   4670:           if( iage <= iagemax){
                   4671:            fprintf(ficresp," %d",iage);
                   4672:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4673:           }
1.240     brouard  4674:        }
1.265     brouard  4675:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4676:          if(pos>=1.e-5){
1.251     brouard  4677:            if(first==1)
1.265     brouard  4678:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4679:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4680:          }else{
                   4681:            if(first==1)
1.265     brouard  4682:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4683:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4684:          }
                   4685:          if( iage <= iagemax){
                   4686:            if(pos>=1.e-5){
1.265     brouard  4687:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4688:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4689:               }else if( nj==2){
                   4690:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4691:               }
                   4692:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4693:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4694:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4695:            } else{
                   4696:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4697:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4698:            }
1.240     brouard  4699:          }
1.265     brouard  4700:          pospropt[s1] +=posprop[s1];
                   4701:        } /* end loop s1 */
1.251     brouard  4702:        /* pospropt=0.; */
1.265     brouard  4703:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4704:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4705:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4706:              if(first==1){
1.265     brouard  4707:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4708:              }
1.265     brouard  4709:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4710:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4711:            }
1.265     brouard  4712:            if(s1!=0 && m!=0)
                   4713:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4714:          }
1.265     brouard  4715:        } /* end loop s1 */
1.251     brouard  4716:        posproptt=0.; 
1.265     brouard  4717:        for(s1=1; s1 <=nlstate; s1++){
                   4718:          posproptt += pospropt[s1];
1.251     brouard  4719:        }
                   4720:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4721:        fprintf(ficresphtm,"</tr>\n");
                   4722:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4723:          if(iage <= iagemax)
                   4724:            fprintf(ficresp,"\n");
1.240     brouard  4725:        }
1.251     brouard  4726:        if(first==1)
                   4727:          printf("Others in log...\n");
                   4728:        fprintf(ficlog,"\n");
                   4729:       } /* end loop age iage */
1.265     brouard  4730:       
1.251     brouard  4731:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4732:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4733:        if(posproptt < 1.e-5){
1.265     brouard  4734:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4735:        }else{
1.265     brouard  4736:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4737:        }
1.226     brouard  4738:       }
1.251     brouard  4739:       fprintf(ficresphtm,"</tr>\n");
                   4740:       fprintf(ficresphtm,"</table>\n");
                   4741:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4742:       if(posproptt < 1.e-5){
1.251     brouard  4743:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4744:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4745:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4746:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4747:        invalidvarcomb[j1]=1;
1.226     brouard  4748:       }else{
1.251     brouard  4749:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4750:        invalidvarcomb[j1]=0;
1.226     brouard  4751:       }
1.251     brouard  4752:       fprintf(ficresphtmfr,"</table>\n");
                   4753:       fprintf(ficlog,"\n");
                   4754:       if(j!=0){
                   4755:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4756:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4757:          for(k=1; k <=(nlstate+ndeath); k++){
                   4758:            if (k != i) {
1.265     brouard  4759:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4760:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4761:                  if(j1==1){ /* All dummy covariates to zero */
                   4762:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4763:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4764:                    printf("%d%d ",i,k);
                   4765:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4766:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4767:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4768:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4769:                  }
1.253     brouard  4770:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4771:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4772:                    x[iage]= (double)iage;
                   4773:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4774:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4775:                  }
1.268     brouard  4776:                  /* Some are not finite, but linreg will ignore these ages */
                   4777:                  no=0;
1.253     brouard  4778:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4779:                  pstart[s1]=b;
                   4780:                  pstart[s1-1]=a;
1.252     brouard  4781:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4782:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4783:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4784:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4785:                  printf("%d%d ",i,k);
                   4786:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4787:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4788:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4789:                  ;
                   4790:                }
                   4791:                /* printf("%12.7f )", param[i][jj][k]); */
                   4792:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4793:                s1++; 
1.251     brouard  4794:              } /* end jj */
                   4795:            } /* end k!= i */
                   4796:          } /* end k */
1.265     brouard  4797:        } /* end i, s1 */
1.251     brouard  4798:       } /* end j !=0 */
                   4799:     } /* end selected combination of covariate j1 */
                   4800:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4801:       printf("#Freqsummary: Starting values for the constants:\n");
                   4802:       fprintf(ficlog,"\n");
1.265     brouard  4803:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4804:        for(k=1; k <=(nlstate+ndeath); k++){
                   4805:          if (k != i) {
                   4806:            printf("%d%d ",i,k);
                   4807:            fprintf(ficlog,"%d%d ",i,k);
                   4808:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4809:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4810:              if(jj==1){ /* Age has to be done */
1.265     brouard  4811:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4812:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4813:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4814:              }
                   4815:              /* printf("%12.7f )", param[i][jj][k]); */
                   4816:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4817:              s1++; 
1.250     brouard  4818:            }
1.251     brouard  4819:            printf("\n");
                   4820:            fprintf(ficlog,"\n");
1.250     brouard  4821:          }
                   4822:        }
                   4823:       }
1.251     brouard  4824:       printf("#Freqsummary\n");
                   4825:       fprintf(ficlog,"\n");
1.265     brouard  4826:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4827:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4828:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4829:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4830:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4831:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4832:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4833:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4834:          /* } */
                   4835:        }
1.265     brouard  4836:       } /* end loop s1 */
1.251     brouard  4837:       
                   4838:       printf("\n");
                   4839:       fprintf(ficlog,"\n");
                   4840:     } /* end j=0 */
1.249     brouard  4841:   } /* end j */
1.252     brouard  4842: 
1.253     brouard  4843:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4844:     for(i=1, jk=1; i <=nlstate; i++){
                   4845:       for(j=1; j <=nlstate+ndeath; j++){
                   4846:        if(j!=i){
                   4847:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4848:          printf("%1d%1d",i,j);
                   4849:          fprintf(ficparo,"%1d%1d",i,j);
                   4850:          for(k=1; k<=ncovmodel;k++){
                   4851:            /*    printf(" %lf",param[i][j][k]); */
                   4852:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4853:            p[jk]=pstart[jk];
                   4854:            printf(" %f ",pstart[jk]);
                   4855:            fprintf(ficparo," %f ",pstart[jk]);
                   4856:            jk++;
                   4857:          }
                   4858:          printf("\n");
                   4859:          fprintf(ficparo,"\n");
                   4860:        }
                   4861:       }
                   4862:     }
                   4863:   } /* end mle=-2 */
1.226     brouard  4864:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4865:   
1.226     brouard  4866:   fclose(ficresp);
                   4867:   fclose(ficresphtm);
                   4868:   fclose(ficresphtmfr);
                   4869:   free_vector(meanq,1,nqfveff);
                   4870:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4871:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4872:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4873:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4874:   free_vector(pospropt,1,nlstate);
                   4875:   free_vector(posprop,1,nlstate);
1.251     brouard  4876:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4877:   free_vector(pp,1,nlstate);
                   4878:   /* End of freqsummary */
                   4879: }
1.126     brouard  4880: 
1.268     brouard  4881: /* Simple linear regression */
                   4882: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4883: 
                   4884:   /* y=a+bx regression */
                   4885:   double   sumx = 0.0;                        /* sum of x                      */
                   4886:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4887:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4888:   double   sumy = 0.0;                        /* sum of y                      */
                   4889:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4890:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4891:   double yhat;
                   4892:   
                   4893:   double denom=0;
                   4894:   int i;
                   4895:   int ne=*no;
                   4896:   
                   4897:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4898:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4899:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4900:       continue;
                   4901:     }
                   4902:     ne=ne+1;
                   4903:     sumx  += x[i];       
                   4904:     sumx2 += x[i]*x[i];  
                   4905:     sumxy += x[i] * y[i];
                   4906:     sumy  += y[i];      
                   4907:     sumy2 += y[i]*y[i]; 
                   4908:     denom = (ne * sumx2 - sumx*sumx);
                   4909:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4910:   } 
                   4911:   
                   4912:   denom = (ne * sumx2 - sumx*sumx);
                   4913:   if (denom == 0) {
                   4914:     // vertical, slope m is infinity
                   4915:     *b = INFINITY;
                   4916:     *a = 0;
                   4917:     if (r) *r = 0;
                   4918:     return 1;
                   4919:   }
                   4920:   
                   4921:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4922:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4923:   if (r!=NULL) {
                   4924:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4925:       sqrt((sumx2 - sumx*sumx/ne) *
                   4926:           (sumy2 - sumy*sumy/ne));
                   4927:   }
                   4928:   *no=ne;
                   4929:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4930:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4931:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4932:       continue;
                   4933:     }
                   4934:     ne=ne+1;
                   4935:     yhat = y[i] - *a -*b* x[i];
                   4936:     sume2  += yhat * yhat ;       
                   4937:     
                   4938:     denom = (ne * sumx2 - sumx*sumx);
                   4939:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4940:   } 
                   4941:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4942:   *sa= *sb * sqrt(sumx2/ne);
                   4943:   
                   4944:   return 0; 
                   4945: }
                   4946: 
1.126     brouard  4947: /************ Prevalence ********************/
1.227     brouard  4948: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4949: {  
                   4950:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4951:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4952:      We still use firstpass and lastpass as another selection.
                   4953:   */
1.126     brouard  4954:  
1.227     brouard  4955:   int i, m, jk, j1, bool, z1,j, iv;
                   4956:   int mi; /* Effective wave */
                   4957:   int iage;
                   4958:   double agebegin, ageend;
                   4959: 
                   4960:   double **prop;
                   4961:   double posprop; 
                   4962:   double  y2; /* in fractional years */
                   4963:   int iagemin, iagemax;
                   4964:   int first; /** to stop verbosity which is redirected to log file */
                   4965: 
                   4966:   iagemin= (int) agemin;
                   4967:   iagemax= (int) agemax;
                   4968:   /*pp=vector(1,nlstate);*/
1.251     brouard  4969:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4970:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4971:   j1=0;
1.222     brouard  4972:   
1.227     brouard  4973:   /*j=cptcoveff;*/
                   4974:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4975:   
1.227     brouard  4976:   first=1;
                   4977:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4978:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4979:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4980:        prop[i][iage]=0.0;
                   4981:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4982:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4983:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4984:     
                   4985:     for (i=1; i<=imx; i++) { /* Each individual */
                   4986:       bool=1;
                   4987:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4988:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4989:        m=mw[mi][i];
                   4990:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4991:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4992:        for (z1=1; z1<=cptcoveff; z1++){
                   4993:          if( Fixed[Tmodelind[z1]]==1){
                   4994:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4995:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4996:              bool=0;
                   4997:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4998:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4999:              bool=0;
                   5000:            }
                   5001:        }
                   5002:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5003:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5004:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5005:          if(m >=firstpass && m <=lastpass){
                   5006:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5007:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5008:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5009:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5010:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5011:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5012:                exit(1);
                   5013:              }
                   5014:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5015:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5016:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5017:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5018:              } /* end valid statuses */ 
                   5019:            } /* end selection of dates */
                   5020:          } /* end selection of waves */
                   5021:        } /* end bool */
                   5022:       } /* end wave */
                   5023:     } /* end individual */
                   5024:     for(i=iagemin; i <= iagemax+3; i++){  
                   5025:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5026:        posprop += prop[jk][i]; 
                   5027:       } 
                   5028:       
                   5029:       for(jk=1; jk <=nlstate ; jk++){      
                   5030:        if( i <=  iagemax){ 
                   5031:          if(posprop>=1.e-5){ 
                   5032:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5033:          } else{
                   5034:            if(first==1){
                   5035:              first=0;
1.266     brouard  5036:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5037:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5038:            }else{
                   5039:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5040:            }
                   5041:          }
                   5042:        } 
                   5043:       }/* end jk */ 
                   5044:     }/* end i */ 
1.222     brouard  5045:      /*} *//* end i1 */
1.227     brouard  5046:   } /* end j1 */
1.222     brouard  5047:   
1.227     brouard  5048:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5049:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5050:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5051: }  /* End of prevalence */
1.126     brouard  5052: 
                   5053: /************* Waves Concatenation ***************/
                   5054: 
                   5055: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5056: {
                   5057:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5058:      Death is a valid wave (if date is known).
                   5059:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5060:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5061:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5062:   */
1.126     brouard  5063: 
1.224     brouard  5064:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5065:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5066:      double sum=0., jmean=0.;*/
1.224     brouard  5067:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5068:   int j, k=0,jk, ju, jl;
                   5069:   double sum=0.;
                   5070:   first=0;
1.214     brouard  5071:   firstwo=0;
1.217     brouard  5072:   firsthree=0;
1.218     brouard  5073:   firstfour=0;
1.164     brouard  5074:   jmin=100000;
1.126     brouard  5075:   jmax=-1;
                   5076:   jmean=0.;
1.224     brouard  5077: 
                   5078: /* Treating live states */
1.214     brouard  5079:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5080:     mi=0;  /* First valid wave */
1.227     brouard  5081:     mli=0; /* Last valid wave */
1.126     brouard  5082:     m=firstpass;
1.214     brouard  5083:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5084:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5085:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5086:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5087:        mw[++mi][i]=m;
                   5088:        mli=m;
1.224     brouard  5089:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5090:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5091:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5092:       }
1.227     brouard  5093:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5094: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5095:        break;
1.224     brouard  5096: #else
1.227     brouard  5097:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5098:          if(firsthree == 0){
1.262     brouard  5099:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5100:            firsthree=1;
                   5101:          }
1.262     brouard  5102:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5103:          mw[++mi][i]=m;
                   5104:          mli=m;
                   5105:        }
                   5106:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5107:          nbwarn++;
                   5108:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5109:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5110:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5111:          }
                   5112:          break;
                   5113:        }
                   5114:        break;
1.224     brouard  5115: #endif
1.227     brouard  5116:       }/* End m >= lastpass */
1.126     brouard  5117:     }/* end while */
1.224     brouard  5118: 
1.227     brouard  5119:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5120:     /* After last pass */
1.224     brouard  5121: /* Treating death states */
1.214     brouard  5122:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5123:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5124:       /* } */
1.126     brouard  5125:       mi++;    /* Death is another wave */
                   5126:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5127:       /* Only death is a correct wave */
1.126     brouard  5128:       mw[mi][i]=m;
1.257     brouard  5129:     } /* else not in a death state */
1.224     brouard  5130: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5131:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5132:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5133:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5134:          nbwarn++;
                   5135:          if(firstfiv==0){
                   5136:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5137:            firstfiv=1;
                   5138:          }else{
                   5139:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5140:          }
                   5141:        }else{ /* Death occured afer last wave potential bias */
                   5142:          nberr++;
                   5143:          if(firstwo==0){
1.257     brouard  5144:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5145:            firstwo=1;
                   5146:          }
1.257     brouard  5147:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5148:        }
1.257     brouard  5149:       }else{ /* if date of interview is unknown */
1.227     brouard  5150:        /* death is known but not confirmed by death status at any wave */
                   5151:        if(firstfour==0){
                   5152:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5153:          firstfour=1;
                   5154:        }
                   5155:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5156:       }
1.224     brouard  5157:     } /* end if date of death is known */
                   5158: #endif
                   5159:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5160:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5161:     if(mi==0){
                   5162:       nbwarn++;
                   5163:       if(first==0){
1.227     brouard  5164:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5165:        first=1;
1.126     brouard  5166:       }
                   5167:       if(first==1){
1.227     brouard  5168:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5169:       }
                   5170:     } /* end mi==0 */
                   5171:   } /* End individuals */
1.214     brouard  5172:   /* wav and mw are no more changed */
1.223     brouard  5173:        
1.214     brouard  5174:   
1.126     brouard  5175:   for(i=1; i<=imx; i++){
                   5176:     for(mi=1; mi<wav[i];mi++){
                   5177:       if (stepm <=0)
1.227     brouard  5178:        dh[mi][i]=1;
1.126     brouard  5179:       else{
1.260     brouard  5180:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5181:          if (agedc[i] < 2*AGESUP) {
                   5182:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5183:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5184:            else if(j<0){
                   5185:              nberr++;
                   5186:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5187:              j=1; /* Temporary Dangerous patch */
                   5188:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5189:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5190:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5191:            }
                   5192:            k=k+1;
                   5193:            if (j >= jmax){
                   5194:              jmax=j;
                   5195:              ijmax=i;
                   5196:            }
                   5197:            if (j <= jmin){
                   5198:              jmin=j;
                   5199:              ijmin=i;
                   5200:            }
                   5201:            sum=sum+j;
                   5202:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5203:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5204:          }
                   5205:        }
                   5206:        else{
                   5207:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5208: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5209:                                        
1.227     brouard  5210:          k=k+1;
                   5211:          if (j >= jmax) {
                   5212:            jmax=j;
                   5213:            ijmax=i;
                   5214:          }
                   5215:          else if (j <= jmin){
                   5216:            jmin=j;
                   5217:            ijmin=i;
                   5218:          }
                   5219:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5220:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5221:          if(j<0){
                   5222:            nberr++;
                   5223:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5224:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5225:          }
                   5226:          sum=sum+j;
                   5227:        }
                   5228:        jk= j/stepm;
                   5229:        jl= j -jk*stepm;
                   5230:        ju= j -(jk+1)*stepm;
                   5231:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5232:          if(jl==0){
                   5233:            dh[mi][i]=jk;
                   5234:            bh[mi][i]=0;
                   5235:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5236:                  * to avoid the price of an extra matrix product in likelihood */
                   5237:            dh[mi][i]=jk+1;
                   5238:            bh[mi][i]=ju;
                   5239:          }
                   5240:        }else{
                   5241:          if(jl <= -ju){
                   5242:            dh[mi][i]=jk;
                   5243:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5244:                                 * is higher than the multiple of stepm and negative otherwise.
                   5245:                                 */
                   5246:          }
                   5247:          else{
                   5248:            dh[mi][i]=jk+1;
                   5249:            bh[mi][i]=ju;
                   5250:          }
                   5251:          if(dh[mi][i]==0){
                   5252:            dh[mi][i]=1; /* At least one step */
                   5253:            bh[mi][i]=ju; /* At least one step */
                   5254:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5255:          }
                   5256:        } /* end if mle */
1.126     brouard  5257:       }
                   5258:     } /* end wave */
                   5259:   }
                   5260:   jmean=sum/k;
                   5261:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5262:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5263: }
1.126     brouard  5264: 
                   5265: /*********** Tricode ****************************/
1.220     brouard  5266:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5267:  {
                   5268:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5269:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5270:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5271:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5272:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5273:     */
1.130     brouard  5274: 
1.242     brouard  5275:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5276:    int modmaxcovj=0; /* Modality max of covariates j */
                   5277:    int cptcode=0; /* Modality max of covariates j */
                   5278:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5279: 
                   5280: 
1.242     brouard  5281:    /* cptcoveff=0;  */
                   5282:    /* *cptcov=0; */
1.126     brouard  5283:  
1.242     brouard  5284:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5285: 
1.242     brouard  5286:    /* Loop on covariates without age and products and no quantitative variable */
                   5287:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5288:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5289:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5290:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5291:        switch(Fixed[k]) {
                   5292:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5293:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5294:           ij=(int)(covar[Tvar[k]][i]);
                   5295:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5296:            * If product of Vn*Vm, still boolean *:
                   5297:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5298:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5299:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5300:              modality of the nth covariate of individual i. */
                   5301:           if (ij > modmaxcovj)
                   5302:             modmaxcovj=ij; 
                   5303:           else if (ij < modmincovj) 
                   5304:             modmincovj=ij; 
                   5305:           if ((ij < -1) && (ij > NCOVMAX)){
                   5306:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5307:             exit(1);
                   5308:           }else
                   5309:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5310:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5311:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5312:           /* getting the maximum value of the modality of the covariate
                   5313:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5314:              female ies 1, then modmaxcovj=1.
                   5315:           */
                   5316:         } /* end for loop on individuals i */
                   5317:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5318:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5319:         cptcode=modmaxcovj;
                   5320:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5321:         /*for (i=0; i<=cptcode; i++) {*/
                   5322:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5323:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5324:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5325:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5326:             if( j != -1){
                   5327:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5328:                                  covariate for which somebody answered excluding 
                   5329:                                  undefined. Usually 2: 0 and 1. */
                   5330:             }
                   5331:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5332:                                     covariate for which somebody answered including 
                   5333:                                     undefined. Usually 3: -1, 0 and 1. */
                   5334:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5335:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5336:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5337:                        
1.242     brouard  5338:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5339:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5340:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5341:         /* modmincovj=3; modmaxcovj = 7; */
                   5342:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5343:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5344:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5345:         /* nbcode[Tvar[j]][ij]=k; */
                   5346:         /* nbcode[Tvar[j]][1]=0; */
                   5347:         /* nbcode[Tvar[j]][2]=1; */
                   5348:         /* nbcode[Tvar[j]][3]=2; */
                   5349:         /* To be continued (not working yet). */
                   5350:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5351:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5352:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5353:             break;
                   5354:           }
                   5355:           ij++;
                   5356:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5357:           cptcode = ij; /* New max modality for covar j */
                   5358:         } /* end of loop on modality i=-1 to 1 or more */
                   5359:         break;
                   5360:        case 1: /* Testing on varying covariate, could be simple and
                   5361:                * should look at waves or product of fixed *
                   5362:                * varying. No time to test -1, assuming 0 and 1 only */
                   5363:         ij=0;
                   5364:         for(i=0; i<=1;i++){
                   5365:           nbcode[Tvar[k]][++ij]=i;
                   5366:         }
                   5367:         break;
                   5368:        default:
                   5369:         break;
                   5370:        } /* end switch */
                   5371:      } /* end dummy test */
                   5372:     
                   5373:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5374:      /*        /\*recode from 0 *\/ */
                   5375:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5376:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5377:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5378:      /*        } */
                   5379:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5380:      /*        if (ij > ncodemax[j]) { */
                   5381:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5382:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5383:      /*          break; */
                   5384:      /*        } */
                   5385:      /*   }  /\* end of loop on modality k *\/ */
                   5386:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5387:   
                   5388:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5389:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5390:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5391:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5392:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5393:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5394:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5395:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5396:   
                   5397:    ij=0;
                   5398:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5399:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5400:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5401:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5402:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5403:        /* If product not in single variable we don't print results */
                   5404:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5405:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5406:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5407:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5408:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5409:        if(Fixed[k]!=0)
                   5410:         anyvaryingduminmodel=1;
                   5411:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5412:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5413:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5414:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5415:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5416:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5417:      } 
                   5418:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5419:    /* ij--; */
                   5420:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5421:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5422:                * because they can be excluded from the model and real
                   5423:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5424:    for(j=ij+1; j<= cptcovt; j++){
                   5425:      Tvaraff[j]=0;
                   5426:      Tmodelind[j]=0;
                   5427:    }
                   5428:    for(j=ntveff+1; j<= cptcovt; j++){
                   5429:      TmodelInvind[j]=0;
                   5430:    }
                   5431:    /* To be sorted */
                   5432:    ;
                   5433:  }
1.126     brouard  5434: 
1.145     brouard  5435: 
1.126     brouard  5436: /*********** Health Expectancies ****************/
                   5437: 
1.235     brouard  5438:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5439: 
                   5440: {
                   5441:   /* Health expectancies, no variances */
1.164     brouard  5442:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5443:   int nhstepma, nstepma; /* Decreasing with age */
                   5444:   double age, agelim, hf;
                   5445:   double ***p3mat;
                   5446:   double eip;
                   5447: 
1.238     brouard  5448:   /* pstamp(ficreseij); */
1.126     brouard  5449:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5450:   fprintf(ficreseij,"# Age");
                   5451:   for(i=1; i<=nlstate;i++){
                   5452:     for(j=1; j<=nlstate;j++){
                   5453:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5454:     }
                   5455:     fprintf(ficreseij," e%1d. ",i);
                   5456:   }
                   5457:   fprintf(ficreseij,"\n");
                   5458: 
                   5459:   
                   5460:   if(estepm < stepm){
                   5461:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5462:   }
                   5463:   else  hstepm=estepm;   
                   5464:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5465:    * This is mainly to measure the difference between two models: for example
                   5466:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5467:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5468:    * progression in between and thus overestimating or underestimating according
                   5469:    * to the curvature of the survival function. If, for the same date, we 
                   5470:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5471:    * to compare the new estimate of Life expectancy with the same linear 
                   5472:    * hypothesis. A more precise result, taking into account a more precise
                   5473:    * curvature will be obtained if estepm is as small as stepm. */
                   5474: 
                   5475:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5476:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5477:      nhstepm is the number of hstepm from age to agelim 
                   5478:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5479:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5480:      and note for a fixed period like estepm months */
                   5481:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5482:      survival function given by stepm (the optimization length). Unfortunately it
                   5483:      means that if the survival funtion is printed only each two years of age and if
                   5484:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5485:      results. So we changed our mind and took the option of the best precision.
                   5486:   */
                   5487:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5488: 
                   5489:   agelim=AGESUP;
                   5490:   /* If stepm=6 months */
                   5491:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5492:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5493:     
                   5494: /* nhstepm age range expressed in number of stepm */
                   5495:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5496:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5497:   /* if (stepm >= YEARM) hstepm=1;*/
                   5498:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5499:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5500: 
                   5501:   for (age=bage; age<=fage; age ++){ 
                   5502:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5503:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5504:     /* if (stepm >= YEARM) hstepm=1;*/
                   5505:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5506: 
                   5507:     /* If stepm=6 months */
                   5508:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5509:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5510:     
1.235     brouard  5511:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5512:     
                   5513:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5514:     
                   5515:     printf("%d|",(int)age);fflush(stdout);
                   5516:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5517:     
                   5518:     /* Computing expectancies */
                   5519:     for(i=1; i<=nlstate;i++)
                   5520:       for(j=1; j<=nlstate;j++)
                   5521:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5522:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5523:          
                   5524:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5525: 
                   5526:        }
                   5527: 
                   5528:     fprintf(ficreseij,"%3.0f",age );
                   5529:     for(i=1; i<=nlstate;i++){
                   5530:       eip=0;
                   5531:       for(j=1; j<=nlstate;j++){
                   5532:        eip +=eij[i][j][(int)age];
                   5533:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5534:       }
                   5535:       fprintf(ficreseij,"%9.4f", eip );
                   5536:     }
                   5537:     fprintf(ficreseij,"\n");
                   5538:     
                   5539:   }
                   5540:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5541:   printf("\n");
                   5542:   fprintf(ficlog,"\n");
                   5543:   
                   5544: }
                   5545: 
1.235     brouard  5546:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5547: 
                   5548: {
                   5549:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5550:      to initial status i, ei. .
1.126     brouard  5551:   */
                   5552:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5553:   int nhstepma, nstepma; /* Decreasing with age */
                   5554:   double age, agelim, hf;
                   5555:   double ***p3matp, ***p3matm, ***varhe;
                   5556:   double **dnewm,**doldm;
                   5557:   double *xp, *xm;
                   5558:   double **gp, **gm;
                   5559:   double ***gradg, ***trgradg;
                   5560:   int theta;
                   5561: 
                   5562:   double eip, vip;
                   5563: 
                   5564:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5565:   xp=vector(1,npar);
                   5566:   xm=vector(1,npar);
                   5567:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5568:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5569:   
                   5570:   pstamp(ficresstdeij);
                   5571:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5572:   fprintf(ficresstdeij,"# Age");
                   5573:   for(i=1; i<=nlstate;i++){
                   5574:     for(j=1; j<=nlstate;j++)
                   5575:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5576:     fprintf(ficresstdeij," e%1d. ",i);
                   5577:   }
                   5578:   fprintf(ficresstdeij,"\n");
                   5579: 
                   5580:   pstamp(ficrescveij);
                   5581:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5582:   fprintf(ficrescveij,"# Age");
                   5583:   for(i=1; i<=nlstate;i++)
                   5584:     for(j=1; j<=nlstate;j++){
                   5585:       cptj= (j-1)*nlstate+i;
                   5586:       for(i2=1; i2<=nlstate;i2++)
                   5587:        for(j2=1; j2<=nlstate;j2++){
                   5588:          cptj2= (j2-1)*nlstate+i2;
                   5589:          if(cptj2 <= cptj)
                   5590:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5591:        }
                   5592:     }
                   5593:   fprintf(ficrescveij,"\n");
                   5594:   
                   5595:   if(estepm < stepm){
                   5596:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5597:   }
                   5598:   else  hstepm=estepm;   
                   5599:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5600:    * This is mainly to measure the difference between two models: for example
                   5601:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5602:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5603:    * progression in between and thus overestimating or underestimating according
                   5604:    * to the curvature of the survival function. If, for the same date, we 
                   5605:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5606:    * to compare the new estimate of Life expectancy with the same linear 
                   5607:    * hypothesis. A more precise result, taking into account a more precise
                   5608:    * curvature will be obtained if estepm is as small as stepm. */
                   5609: 
                   5610:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5611:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5612:      nhstepm is the number of hstepm from age to agelim 
                   5613:      nstepm is the number of stepm from age to agelin. 
                   5614:      Look at hpijx to understand the reason of that which relies in memory size
                   5615:      and note for a fixed period like estepm months */
                   5616:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5617:      survival function given by stepm (the optimization length). Unfortunately it
                   5618:      means that if the survival funtion is printed only each two years of age and if
                   5619:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5620:      results. So we changed our mind and took the option of the best precision.
                   5621:   */
                   5622:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5623: 
                   5624:   /* If stepm=6 months */
                   5625:   /* nhstepm age range expressed in number of stepm */
                   5626:   agelim=AGESUP;
                   5627:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5628:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5629:   /* if (stepm >= YEARM) hstepm=1;*/
                   5630:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5631:   
                   5632:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5633:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5634:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5635:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5636:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5637:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5638: 
                   5639:   for (age=bage; age<=fage; age ++){ 
                   5640:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5641:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5642:     /* if (stepm >= YEARM) hstepm=1;*/
                   5643:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5644:                
1.126     brouard  5645:     /* If stepm=6 months */
                   5646:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5647:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5648:     
                   5649:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5650:                
1.126     brouard  5651:     /* Computing  Variances of health expectancies */
                   5652:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5653:        decrease memory allocation */
                   5654:     for(theta=1; theta <=npar; theta++){
                   5655:       for(i=1; i<=npar; i++){ 
1.222     brouard  5656:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5657:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5658:       }
1.235     brouard  5659:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5660:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5661:                        
1.126     brouard  5662:       for(j=1; j<= nlstate; j++){
1.222     brouard  5663:        for(i=1; i<=nlstate; i++){
                   5664:          for(h=0; h<=nhstepm-1; h++){
                   5665:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5666:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5667:          }
                   5668:        }
1.126     brouard  5669:       }
1.218     brouard  5670:                        
1.126     brouard  5671:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5672:        for(h=0; h<=nhstepm-1; h++){
                   5673:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5674:        }
1.126     brouard  5675:     }/* End theta */
                   5676:     
                   5677:     
                   5678:     for(h=0; h<=nhstepm-1; h++)
                   5679:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5680:        for(theta=1; theta <=npar; theta++)
                   5681:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5682:     
1.218     brouard  5683:                
1.222     brouard  5684:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5685:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5686:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5687:                
1.222     brouard  5688:     printf("%d|",(int)age);fflush(stdout);
                   5689:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5690:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5691:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5692:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5693:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5694:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5695:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5696:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5697:       }
                   5698:     }
1.218     brouard  5699:                
1.126     brouard  5700:     /* Computing expectancies */
1.235     brouard  5701:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5702:     for(i=1; i<=nlstate;i++)
                   5703:       for(j=1; j<=nlstate;j++)
1.222     brouard  5704:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5705:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5706:                                        
1.222     brouard  5707:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5708:                                        
1.222     brouard  5709:        }
1.269     brouard  5710: 
                   5711:     /* Standard deviation of expectancies ij */                
1.126     brouard  5712:     fprintf(ficresstdeij,"%3.0f",age );
                   5713:     for(i=1; i<=nlstate;i++){
                   5714:       eip=0.;
                   5715:       vip=0.;
                   5716:       for(j=1; j<=nlstate;j++){
1.222     brouard  5717:        eip += eij[i][j][(int)age];
                   5718:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5719:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5720:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5721:       }
                   5722:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5723:     }
                   5724:     fprintf(ficresstdeij,"\n");
1.218     brouard  5725:                
1.269     brouard  5726:     /* Variance of expectancies ij */          
1.126     brouard  5727:     fprintf(ficrescveij,"%3.0f",age );
                   5728:     for(i=1; i<=nlstate;i++)
                   5729:       for(j=1; j<=nlstate;j++){
1.222     brouard  5730:        cptj= (j-1)*nlstate+i;
                   5731:        for(i2=1; i2<=nlstate;i2++)
                   5732:          for(j2=1; j2<=nlstate;j2++){
                   5733:            cptj2= (j2-1)*nlstate+i2;
                   5734:            if(cptj2 <= cptj)
                   5735:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5736:          }
1.126     brouard  5737:       }
                   5738:     fprintf(ficrescveij,"\n");
1.218     brouard  5739:                
1.126     brouard  5740:   }
                   5741:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5742:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5743:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5744:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5745:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5746:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5747:   printf("\n");
                   5748:   fprintf(ficlog,"\n");
1.218     brouard  5749:        
1.126     brouard  5750:   free_vector(xm,1,npar);
                   5751:   free_vector(xp,1,npar);
                   5752:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5753:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5754:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5755: }
1.218     brouard  5756:  
1.126     brouard  5757: /************ Variance ******************/
1.235     brouard  5758:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5759:  {
                   5760:    /* Variance of health expectancies */
                   5761:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5762:    /* double **newm;*/
                   5763:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5764:   
                   5765:    /* int movingaverage(); */
                   5766:    double **dnewm,**doldm;
                   5767:    double **dnewmp,**doldmp;
                   5768:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5769:    int k;
                   5770:    double *xp;
                   5771:    double **gp, **gm;  /* for var eij */
                   5772:    double ***gradg, ***trgradg; /*for var eij */
                   5773:    double **gradgp, **trgradgp; /* for var p point j */
                   5774:    double *gpp, *gmp; /* for var p point j */
                   5775:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5776:    double ***p3mat;
                   5777:    double age,agelim, hf;
                   5778:    /* double ***mobaverage; */
                   5779:    int theta;
                   5780:    char digit[4];
                   5781:    char digitp[25];
                   5782: 
                   5783:    char fileresprobmorprev[FILENAMELENGTH];
                   5784: 
                   5785:    if(popbased==1){
                   5786:      if(mobilav!=0)
                   5787:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5788:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5789:    }
                   5790:    else 
                   5791:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5792: 
1.218     brouard  5793:    /* if (mobilav!=0) { */
                   5794:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5795:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5796:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5797:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5798:    /*   } */
                   5799:    /* } */
                   5800: 
                   5801:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5802:    sprintf(digit,"%-d",ij);
                   5803:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5804:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5805:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5806:    strcat(fileresprobmorprev,fileresu);
                   5807:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5808:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5809:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5810:    }
                   5811:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5812:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5813:    pstamp(ficresprobmorprev);
                   5814:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5815:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5816:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5817:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5818:    }
                   5819:    for(j=1;j<=cptcoveff;j++) 
                   5820:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5821:    fprintf(ficresprobmorprev,"\n");
                   5822: 
1.218     brouard  5823:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5824:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5825:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5826:      for(i=1; i<=nlstate;i++)
                   5827:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5828:    }  
                   5829:    fprintf(ficresprobmorprev,"\n");
                   5830:   
                   5831:    fprintf(ficgp,"\n# Routine varevsij");
                   5832:    fprintf(ficgp,"\nunset title \n");
                   5833:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5834:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5835:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5836:    /*   } */
                   5837:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5838:    pstamp(ficresvij);
                   5839:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5840:    if(popbased==1)
                   5841:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5842:    else
                   5843:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5844:    fprintf(ficresvij,"# Age");
                   5845:    for(i=1; i<=nlstate;i++)
                   5846:      for(j=1; j<=nlstate;j++)
                   5847:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5848:    fprintf(ficresvij,"\n");
                   5849: 
                   5850:    xp=vector(1,npar);
                   5851:    dnewm=matrix(1,nlstate,1,npar);
                   5852:    doldm=matrix(1,nlstate,1,nlstate);
                   5853:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5854:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5855: 
                   5856:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5857:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5858:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5859:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5860:   
1.218     brouard  5861:    if(estepm < stepm){
                   5862:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5863:    }
                   5864:    else  hstepm=estepm;   
                   5865:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5866:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5867:       nhstepm is the number of hstepm from age to agelim 
                   5868:       nstepm is the number of stepm from age to agelim. 
                   5869:       Look at function hpijx to understand why because of memory size limitations, 
                   5870:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5871:       survival function given by stepm (the optimization length). Unfortunately it
                   5872:       means that if the survival funtion is printed every two years of age and if
                   5873:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5874:       results. So we changed our mind and took the option of the best precision.
                   5875:    */
                   5876:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5877:    agelim = AGESUP;
                   5878:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5879:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5880:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5881:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5882:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5883:      gp=matrix(0,nhstepm,1,nlstate);
                   5884:      gm=matrix(0,nhstepm,1,nlstate);
                   5885:                
                   5886:                
                   5887:      for(theta=1; theta <=npar; theta++){
                   5888:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5889:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5890:        }
                   5891:                        
1.242     brouard  5892:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5893:                        
                   5894:        if (popbased==1) {
                   5895:         if(mobilav ==0){
                   5896:           for(i=1; i<=nlstate;i++)
                   5897:             prlim[i][i]=probs[(int)age][i][ij];
                   5898:         }else{ /* mobilav */ 
                   5899:           for(i=1; i<=nlstate;i++)
                   5900:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5901:         }
                   5902:        }
                   5903:                        
1.235     brouard  5904:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5905:        for(j=1; j<= nlstate; j++){
                   5906:         for(h=0; h<=nhstepm; h++){
                   5907:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5908:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5909:         }
                   5910:        }
                   5911:        /* Next for computing probability of death (h=1 means
                   5912:          computed over hstepm matrices product = hstepm*stepm months) 
                   5913:          as a weighted average of prlim.
                   5914:        */
                   5915:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5916:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5917:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5918:        }    
                   5919:        /* end probability of death */
                   5920:                        
                   5921:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5922:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5923:                        
1.242     brouard  5924:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5925:                        
                   5926:        if (popbased==1) {
                   5927:         if(mobilav ==0){
                   5928:           for(i=1; i<=nlstate;i++)
                   5929:             prlim[i][i]=probs[(int)age][i][ij];
                   5930:         }else{ /* mobilav */ 
                   5931:           for(i=1; i<=nlstate;i++)
                   5932:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5933:         }
                   5934:        }
                   5935:                        
1.235     brouard  5936:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5937:                        
                   5938:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5939:         for(h=0; h<=nhstepm; h++){
                   5940:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5941:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5942:         }
                   5943:        }
                   5944:        /* This for computing probability of death (h=1 means
                   5945:          computed over hstepm matrices product = hstepm*stepm months) 
                   5946:          as a weighted average of prlim.
                   5947:        */
                   5948:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5949:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5950:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5951:        }    
                   5952:        /* end probability of death */
                   5953:                        
                   5954:        for(j=1; j<= nlstate; j++) /* vareij */
                   5955:         for(h=0; h<=nhstepm; h++){
                   5956:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5957:         }
                   5958:                        
                   5959:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5960:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5961:        }
                   5962:                        
                   5963:      } /* End theta */
                   5964:                
                   5965:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5966:                
                   5967:      for(h=0; h<=nhstepm; h++) /* veij */
                   5968:        for(j=1; j<=nlstate;j++)
                   5969:         for(theta=1; theta <=npar; theta++)
                   5970:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5971:                
                   5972:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5973:        for(theta=1; theta <=npar; theta++)
                   5974:         trgradgp[j][theta]=gradgp[theta][j];
                   5975:                
                   5976:                
                   5977:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5978:      for(i=1;i<=nlstate;i++)
                   5979:        for(j=1;j<=nlstate;j++)
                   5980:         vareij[i][j][(int)age] =0.;
                   5981:                
                   5982:      for(h=0;h<=nhstepm;h++){
                   5983:        for(k=0;k<=nhstepm;k++){
                   5984:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5985:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5986:         for(i=1;i<=nlstate;i++)
                   5987:           for(j=1;j<=nlstate;j++)
                   5988:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5989:        }
                   5990:      }
                   5991:                
                   5992:      /* pptj */
                   5993:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5994:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5995:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5996:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5997:         varppt[j][i]=doldmp[j][i];
                   5998:      /* end ppptj */
                   5999:      /*  x centered again */
                   6000:                
1.242     brouard  6001:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6002:                
                   6003:      if (popbased==1) {
                   6004:        if(mobilav ==0){
                   6005:         for(i=1; i<=nlstate;i++)
                   6006:           prlim[i][i]=probs[(int)age][i][ij];
                   6007:        }else{ /* mobilav */ 
                   6008:         for(i=1; i<=nlstate;i++)
                   6009:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6010:        }
                   6011:      }
                   6012:                
                   6013:      /* This for computing probability of death (h=1 means
                   6014:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6015:        as a weighted average of prlim.
                   6016:      */
1.235     brouard  6017:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6018:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6019:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6020:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6021:      }    
                   6022:      /* end probability of death */
                   6023:                
                   6024:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6025:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6026:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6027:        for(i=1; i<=nlstate;i++){
                   6028:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6029:        }
                   6030:      } 
                   6031:      fprintf(ficresprobmorprev,"\n");
                   6032:                
                   6033:      fprintf(ficresvij,"%.0f ",age );
                   6034:      for(i=1; i<=nlstate;i++)
                   6035:        for(j=1; j<=nlstate;j++){
                   6036:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6037:        }
                   6038:      fprintf(ficresvij,"\n");
                   6039:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6040:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6041:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6042:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6043:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6044:    } /* End age */
                   6045:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6046:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6047:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6048:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6049:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6050:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6051:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6052:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6053:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6054:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6055:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6056:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6057:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6058:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6059:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6060:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6061:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6062:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6063:     */
1.218     brouard  6064:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6065:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6066: 
1.218     brouard  6067:    free_vector(xp,1,npar);
                   6068:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6069:    free_matrix(dnewm,1,nlstate,1,npar);
                   6070:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6071:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6072:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6073:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6074:    fclose(ficresprobmorprev);
                   6075:    fflush(ficgp);
                   6076:    fflush(fichtm); 
                   6077:  }  /* end varevsij */
1.126     brouard  6078: 
                   6079: /************ Variance of prevlim ******************/
1.269     brouard  6080:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6081: {
1.205     brouard  6082:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6083:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6084: 
1.268     brouard  6085:   double **dnewmpar,**doldm;
1.126     brouard  6086:   int i, j, nhstepm, hstepm;
                   6087:   double *xp;
                   6088:   double *gp, *gm;
                   6089:   double **gradg, **trgradg;
1.208     brouard  6090:   double **mgm, **mgp;
1.126     brouard  6091:   double age,agelim;
                   6092:   int theta;
                   6093:   
                   6094:   pstamp(ficresvpl);
                   6095:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6096:   fprintf(ficresvpl,"# Age ");
                   6097:   if(nresult >=1)
                   6098:     fprintf(ficresvpl," Result# ");
1.126     brouard  6099:   for(i=1; i<=nlstate;i++)
                   6100:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6101:   fprintf(ficresvpl,"\n");
                   6102: 
                   6103:   xp=vector(1,npar);
1.268     brouard  6104:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6105:   doldm=matrix(1,nlstate,1,nlstate);
                   6106:   
                   6107:   hstepm=1*YEARM; /* Every year of age */
                   6108:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6109:   agelim = AGESUP;
                   6110:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6111:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6112:     if (stepm >= YEARM) hstepm=1;
                   6113:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6114:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6115:     mgp=matrix(1,npar,1,nlstate);
                   6116:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6117:     gp=vector(1,nlstate);
                   6118:     gm=vector(1,nlstate);
                   6119: 
                   6120:     for(theta=1; theta <=npar; theta++){
                   6121:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6122:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6123:       }
1.209     brouard  6124:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6125:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6126:       else
1.235     brouard  6127:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6128:       for(i=1;i<=nlstate;i++){
1.126     brouard  6129:        gp[i] = prlim[i][i];
1.208     brouard  6130:        mgp[theta][i] = prlim[i][i];
                   6131:       }
1.126     brouard  6132:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6133:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6134:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6135:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6136:       else
1.235     brouard  6137:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6138:       for(i=1;i<=nlstate;i++){
1.126     brouard  6139:        gm[i] = prlim[i][i];
1.208     brouard  6140:        mgm[theta][i] = prlim[i][i];
                   6141:       }
1.126     brouard  6142:       for(i=1;i<=nlstate;i++)
                   6143:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6144:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6145:     } /* End theta */
                   6146: 
                   6147:     trgradg =matrix(1,nlstate,1,npar);
                   6148: 
                   6149:     for(j=1; j<=nlstate;j++)
                   6150:       for(theta=1; theta <=npar; theta++)
                   6151:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6152:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6153:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6154:     /*   for(j=1; j<=nlstate;j++){ */
                   6155:     /*         printf(" %d ",j); */
                   6156:     /*         for(theta=1; theta <=npar; theta++) */
                   6157:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6158:     /*         printf("\n "); */
                   6159:     /*   } */
                   6160:     /* } */
                   6161:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6162:     /*   printf("\n gradg %d ",(int)age); */
                   6163:     /*   for(j=1; j<=nlstate;j++){ */
                   6164:     /*         printf("%d ",j); */
                   6165:     /*         for(theta=1; theta <=npar; theta++) */
                   6166:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6167:     /*         printf("\n "); */
                   6168:     /*   } */
                   6169:     /* } */
1.126     brouard  6170: 
                   6171:     for(i=1;i<=nlstate;i++)
                   6172:       varpl[i][(int)age] =0.;
1.209     brouard  6173:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6174:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6175:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6176:     }else{
1.268     brouard  6177:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6178:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6179:     }
1.126     brouard  6180:     for(i=1;i<=nlstate;i++)
                   6181:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6182: 
                   6183:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6184:     if(nresult >=1)
                   6185:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6186:     for(i=1; i<=nlstate;i++)
                   6187:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6188:     fprintf(ficresvpl,"\n");
                   6189:     free_vector(gp,1,nlstate);
                   6190:     free_vector(gm,1,nlstate);
1.208     brouard  6191:     free_matrix(mgm,1,npar,1,nlstate);
                   6192:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6193:     free_matrix(gradg,1,npar,1,nlstate);
                   6194:     free_matrix(trgradg,1,nlstate,1,npar);
                   6195:   } /* End age */
                   6196: 
                   6197:   free_vector(xp,1,npar);
                   6198:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6199:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6200: 
                   6201: }
                   6202: 
                   6203: 
                   6204: /************ Variance of backprevalence limit ******************/
1.269     brouard  6205:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6206: {
                   6207:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6208:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6209: 
                   6210:   double **dnewmpar,**doldm;
                   6211:   int i, j, nhstepm, hstepm;
                   6212:   double *xp;
                   6213:   double *gp, *gm;
                   6214:   double **gradg, **trgradg;
                   6215:   double **mgm, **mgp;
                   6216:   double age,agelim;
                   6217:   int theta;
                   6218:   
                   6219:   pstamp(ficresvbl);
                   6220:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6221:   fprintf(ficresvbl,"# Age ");
                   6222:   if(nresult >=1)
                   6223:     fprintf(ficresvbl," Result# ");
                   6224:   for(i=1; i<=nlstate;i++)
                   6225:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6226:   fprintf(ficresvbl,"\n");
                   6227: 
                   6228:   xp=vector(1,npar);
                   6229:   dnewmpar=matrix(1,nlstate,1,npar);
                   6230:   doldm=matrix(1,nlstate,1,nlstate);
                   6231:   
                   6232:   hstepm=1*YEARM; /* Every year of age */
                   6233:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6234:   agelim = AGEINF;
                   6235:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6236:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6237:     if (stepm >= YEARM) hstepm=1;
                   6238:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6239:     gradg=matrix(1,npar,1,nlstate);
                   6240:     mgp=matrix(1,npar,1,nlstate);
                   6241:     mgm=matrix(1,npar,1,nlstate);
                   6242:     gp=vector(1,nlstate);
                   6243:     gm=vector(1,nlstate);
                   6244: 
                   6245:     for(theta=1; theta <=npar; theta++){
                   6246:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6247:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6248:       }
                   6249:       if(mobilavproj > 0 )
                   6250:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6251:       else
                   6252:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6253:       for(i=1;i<=nlstate;i++){
                   6254:        gp[i] = bprlim[i][i];
                   6255:        mgp[theta][i] = bprlim[i][i];
                   6256:       }
                   6257:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6258:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6259:        if(mobilavproj > 0 )
                   6260:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6261:        else
                   6262:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6263:       for(i=1;i<=nlstate;i++){
                   6264:        gm[i] = bprlim[i][i];
                   6265:        mgm[theta][i] = bprlim[i][i];
                   6266:       }
                   6267:       for(i=1;i<=nlstate;i++)
                   6268:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6269:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6270:     } /* End theta */
                   6271: 
                   6272:     trgradg =matrix(1,nlstate,1,npar);
                   6273: 
                   6274:     for(j=1; j<=nlstate;j++)
                   6275:       for(theta=1; theta <=npar; theta++)
                   6276:        trgradg[j][theta]=gradg[theta][j];
                   6277:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6278:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6279:     /*   for(j=1; j<=nlstate;j++){ */
                   6280:     /*         printf(" %d ",j); */
                   6281:     /*         for(theta=1; theta <=npar; theta++) */
                   6282:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6283:     /*         printf("\n "); */
                   6284:     /*   } */
                   6285:     /* } */
                   6286:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6287:     /*   printf("\n gradg %d ",(int)age); */
                   6288:     /*   for(j=1; j<=nlstate;j++){ */
                   6289:     /*         printf("%d ",j); */
                   6290:     /*         for(theta=1; theta <=npar; theta++) */
                   6291:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6292:     /*         printf("\n "); */
                   6293:     /*   } */
                   6294:     /* } */
                   6295: 
                   6296:     for(i=1;i<=nlstate;i++)
                   6297:       varbpl[i][(int)age] =0.;
                   6298:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6299:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6300:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6301:     }else{
                   6302:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6303:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6304:     }
                   6305:     for(i=1;i<=nlstate;i++)
                   6306:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6307: 
                   6308:     fprintf(ficresvbl,"%.0f ",age );
                   6309:     if(nresult >=1)
                   6310:       fprintf(ficresvbl,"%d ",nres );
                   6311:     for(i=1; i<=nlstate;i++)
                   6312:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6313:     fprintf(ficresvbl,"\n");
                   6314:     free_vector(gp,1,nlstate);
                   6315:     free_vector(gm,1,nlstate);
                   6316:     free_matrix(mgm,1,npar,1,nlstate);
                   6317:     free_matrix(mgp,1,npar,1,nlstate);
                   6318:     free_matrix(gradg,1,npar,1,nlstate);
                   6319:     free_matrix(trgradg,1,nlstate,1,npar);
                   6320:   } /* End age */
                   6321: 
                   6322:   free_vector(xp,1,npar);
                   6323:   free_matrix(doldm,1,nlstate,1,npar);
                   6324:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6325: 
                   6326: }
                   6327: 
                   6328: /************ Variance of one-step probabilities  ******************/
                   6329: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6330:  {
                   6331:    int i, j=0,  k1, l1, tj;
                   6332:    int k2, l2, j1,  z1;
                   6333:    int k=0, l;
                   6334:    int first=1, first1, first2;
                   6335:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6336:    double **dnewm,**doldm;
                   6337:    double *xp;
                   6338:    double *gp, *gm;
                   6339:    double **gradg, **trgradg;
                   6340:    double **mu;
                   6341:    double age, cov[NCOVMAX+1];
                   6342:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6343:    int theta;
                   6344:    char fileresprob[FILENAMELENGTH];
                   6345:    char fileresprobcov[FILENAMELENGTH];
                   6346:    char fileresprobcor[FILENAMELENGTH];
                   6347:    double ***varpij;
                   6348: 
                   6349:    strcpy(fileresprob,"PROB_"); 
                   6350:    strcat(fileresprob,fileres);
                   6351:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6352:      printf("Problem with resultfile: %s\n", fileresprob);
                   6353:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6354:    }
                   6355:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6356:    strcat(fileresprobcov,fileresu);
                   6357:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6358:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6359:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6360:    }
                   6361:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6362:    strcat(fileresprobcor,fileresu);
                   6363:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6364:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6365:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6366:    }
                   6367:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6368:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6369:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6370:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6371:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6372:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6373:    pstamp(ficresprob);
                   6374:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6375:    fprintf(ficresprob,"# Age");
                   6376:    pstamp(ficresprobcov);
                   6377:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6378:    fprintf(ficresprobcov,"# Age");
                   6379:    pstamp(ficresprobcor);
                   6380:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6381:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6382: 
                   6383: 
1.222     brouard  6384:    for(i=1; i<=nlstate;i++)
                   6385:      for(j=1; j<=(nlstate+ndeath);j++){
                   6386:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6387:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6388:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6389:      }  
                   6390:    /* fprintf(ficresprob,"\n");
                   6391:       fprintf(ficresprobcov,"\n");
                   6392:       fprintf(ficresprobcor,"\n");
                   6393:    */
                   6394:    xp=vector(1,npar);
                   6395:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6396:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6397:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6398:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6399:    first=1;
                   6400:    fprintf(ficgp,"\n# Routine varprob");
                   6401:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6402:    fprintf(fichtm,"\n");
                   6403: 
1.266     brouard  6404:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6405:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6406:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6407: and drawn. It helps understanding how is the covariance between two incidences.\
                   6408:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6409:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6410: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6411: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6412: standard deviations wide on each axis. <br>\
                   6413:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6414:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6415: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6416: 
1.222     brouard  6417:    cov[1]=1;
                   6418:    /* tj=cptcoveff; */
1.225     brouard  6419:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6420:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6421:    j1=0;
1.224     brouard  6422:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6423:      if  (cptcovn>0) {
                   6424:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6425:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6426:        fprintf(ficresprob, "**********\n#\n");
                   6427:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6428:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6429:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6430:                        
1.222     brouard  6431:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6432:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6433:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6434:                        
                   6435:                        
1.222     brouard  6436:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6437:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6438:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6439:                        
1.222     brouard  6440:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6441:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6442:        fprintf(ficresprobcor, "**********\n#");    
                   6443:        if(invalidvarcomb[j1]){
                   6444:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6445:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6446:         continue;
                   6447:        }
                   6448:      }
                   6449:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6450:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6451:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6452:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6453:      for (age=bage; age<=fage; age ++){ 
                   6454:        cov[2]=age;
                   6455:        if(nagesqr==1)
                   6456:         cov[3]= age*age;
                   6457:        for (k=1; k<=cptcovn;k++) {
                   6458:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6459:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6460:                                                                    * 1  1 1 1 1
                   6461:                                                                    * 2  2 1 1 1
                   6462:                                                                    * 3  1 2 1 1
                   6463:                                                                    */
                   6464:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6465:        }
                   6466:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6467:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6468:        for (k=1; k<=cptcovprod;k++)
                   6469:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6470:                        
                   6471:                        
1.222     brouard  6472:        for(theta=1; theta <=npar; theta++){
                   6473:         for(i=1; i<=npar; i++)
                   6474:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6475:                                
1.222     brouard  6476:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6477:                                
1.222     brouard  6478:         k=0;
                   6479:         for(i=1; i<= (nlstate); i++){
                   6480:           for(j=1; j<=(nlstate+ndeath);j++){
                   6481:             k=k+1;
                   6482:             gp[k]=pmmij[i][j];
                   6483:           }
                   6484:         }
1.220     brouard  6485:                                
1.222     brouard  6486:         for(i=1; i<=npar; i++)
                   6487:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6488:                                
1.222     brouard  6489:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6490:         k=0;
                   6491:         for(i=1; i<=(nlstate); i++){
                   6492:           for(j=1; j<=(nlstate+ndeath);j++){
                   6493:             k=k+1;
                   6494:             gm[k]=pmmij[i][j];
                   6495:           }
                   6496:         }
1.220     brouard  6497:                                
1.222     brouard  6498:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6499:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6500:        }
1.126     brouard  6501: 
1.222     brouard  6502:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6503:         for(theta=1; theta <=npar; theta++)
                   6504:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6505:                        
1.222     brouard  6506:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6507:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6508:                        
1.222     brouard  6509:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6510:                        
1.222     brouard  6511:        k=0;
                   6512:        for(i=1; i<=(nlstate); i++){
                   6513:         for(j=1; j<=(nlstate+ndeath);j++){
                   6514:           k=k+1;
                   6515:           mu[k][(int) age]=pmmij[i][j];
                   6516:         }
                   6517:        }
                   6518:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6519:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6520:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6521:                        
1.222     brouard  6522:        /*printf("\n%d ",(int)age);
                   6523:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6524:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6525:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6526:         }*/
1.220     brouard  6527:                        
1.222     brouard  6528:        fprintf(ficresprob,"\n%d ",(int)age);
                   6529:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6530:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6531:                        
1.222     brouard  6532:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6533:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6534:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6535:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6536:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6537:        }
                   6538:        i=0;
                   6539:        for (k=1; k<=(nlstate);k++){
                   6540:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6541:           i++;
                   6542:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6543:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6544:           for (j=1; j<=i;j++){
                   6545:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6546:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6547:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6548:           }
                   6549:         }
                   6550:        }/* end of loop for state */
                   6551:      } /* end of loop for age */
                   6552:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6553:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6554:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6555:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6556:     
                   6557:      /* Confidence intervalle of pij  */
                   6558:      /*
                   6559:        fprintf(ficgp,"\nunset parametric;unset label");
                   6560:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6561:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6562:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6563:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6564:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6565:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6566:      */
                   6567:                
                   6568:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6569:      first1=1;first2=2;
                   6570:      for (k2=1; k2<=(nlstate);k2++){
                   6571:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6572:         if(l2==k2) continue;
                   6573:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6574:         for (k1=1; k1<=(nlstate);k1++){
                   6575:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6576:             if(l1==k1) continue;
                   6577:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6578:             if(i<=j) continue;
                   6579:             for (age=bage; age<=fage; age ++){ 
                   6580:               if ((int)age %5==0){
                   6581:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6582:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6583:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6584:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6585:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6586:                 c12=cv12/sqrt(v1*v2);
                   6587:                 /* Computing eigen value of matrix of covariance */
                   6588:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6589:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6590:                 if ((lc2 <0) || (lc1 <0) ){
                   6591:                   if(first2==1){
                   6592:                     first1=0;
                   6593:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6594:                   }
                   6595:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6596:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6597:                   /* lc2=fabs(lc2); */
                   6598:                 }
1.220     brouard  6599:                                                                
1.222     brouard  6600:                 /* Eigen vectors */
                   6601:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6602:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6603:                 v21=(lc1-v1)/cv12*v11;
                   6604:                 v12=-v21;
                   6605:                 v22=v11;
                   6606:                 tnalp=v21/v11;
                   6607:                 if(first1==1){
                   6608:                   first1=0;
                   6609:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6610:                 }
                   6611:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6612:                 /*printf(fignu*/
                   6613:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6614:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6615:                 if(first==1){
                   6616:                   first=0;
                   6617:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6618:                   fprintf(ficgp,"\nset parametric;unset label");
                   6619:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6620:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6621:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6622:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6623: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6624:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6625:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6626:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6627:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6628:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6629:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6630:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6631:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6632:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6633:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6634:                 }else{
                   6635:                   first=0;
                   6636:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6637:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6638:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6639:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6640:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6641:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6642:                 }/* if first */
                   6643:               } /* age mod 5 */
                   6644:             } /* end loop age */
                   6645:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6646:             first=1;
                   6647:           } /*l12 */
                   6648:         } /* k12 */
                   6649:        } /*l1 */
                   6650:      }/* k1 */
                   6651:    }  /* loop on combination of covariates j1 */
                   6652:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6653:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6654:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6655:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6656:    free_vector(xp,1,npar);
                   6657:    fclose(ficresprob);
                   6658:    fclose(ficresprobcov);
                   6659:    fclose(ficresprobcor);
                   6660:    fflush(ficgp);
                   6661:    fflush(fichtmcov);
                   6662:  }
1.126     brouard  6663: 
                   6664: 
                   6665: /******************* Printing html file ***********/
1.201     brouard  6666: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6667:                  int lastpass, int stepm, int weightopt, char model[],\
                   6668:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6669:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6670:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6671:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6672:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6673: 
                   6674:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6675:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6676: </ul>");
1.237     brouard  6677:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6678: </ul>", model);
1.214     brouard  6679:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6680:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6681:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6682:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6683:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6684:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6685:    fprintf(fichtm,"\
                   6686:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6687:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6688:    fprintf(fichtm,"\
1.217     brouard  6689:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6690:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6691:    fprintf(fichtm,"\
1.126     brouard  6692:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6693:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6694:    fprintf(fichtm,"\
1.217     brouard  6695:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6696:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6697:    fprintf(fichtm,"\
1.211     brouard  6698:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6699:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6700:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6701:    if(prevfcast==1){
                   6702:      fprintf(fichtm,"\
                   6703:  - Prevalence projections by age and states:                           \
1.201     brouard  6704:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6705:    }
1.126     brouard  6706: 
                   6707: 
1.225     brouard  6708:    m=pow(2,cptcoveff);
1.222     brouard  6709:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6710: 
1.264     brouard  6711:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6712: 
                   6713:    jj1=0;
                   6714: 
                   6715:    fprintf(fichtm," \n<ul>");
                   6716:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6717:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6718:      if(m != 1 && TKresult[nres]!= k1)
                   6719:        continue;
                   6720:      jj1++;
                   6721:      if (cptcovn > 0) {
                   6722:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6723:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6724:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6725:        }
                   6726:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6727:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6728:        }
                   6729:        fprintf(fichtm,"\">");
                   6730:        
                   6731:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6732:        fprintf(fichtm,"************ Results for covariates");
                   6733:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6734:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6735:        }
                   6736:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6737:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6738:        }
                   6739:        if(invalidvarcomb[k1]){
                   6740:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6741:         continue;
                   6742:        }
                   6743:        fprintf(fichtm,"</a></li>");
                   6744:      } /* cptcovn >0 */
                   6745:    }
                   6746:      fprintf(fichtm," \n</ul>");
                   6747: 
1.222     brouard  6748:    jj1=0;
1.237     brouard  6749: 
                   6750:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6751:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6752:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6753:        continue;
1.220     brouard  6754: 
1.222     brouard  6755:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6756:      jj1++;
                   6757:      if (cptcovn > 0) {
1.264     brouard  6758:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6759:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6760:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6761:        }
                   6762:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6763:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6764:        }
                   6765:        fprintf(fichtm,"\"</a>");
                   6766:  
1.222     brouard  6767:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6768:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6769:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6770:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6771:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6772:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6773:        }
1.237     brouard  6774:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6775:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6776:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6777:       }
                   6778:        
1.230     brouard  6779:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6780:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6781:        if(invalidvarcomb[k1]){
                   6782:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6783:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6784:         continue;
                   6785:        }
                   6786:      }
                   6787:      /* aij, bij */
1.259     brouard  6788:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6789: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6790:      /* Pij */
1.241     brouard  6791:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6792: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6793:      /* Quasi-incidences */
                   6794:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6795:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6796:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6797: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6798: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6799:      /* Survival functions (period) in state j */
                   6800:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6801:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6802: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6803:      }
                   6804:      /* State specific survival functions (period) */
                   6805:      for(cpt=1; cpt<=nlstate;cpt++){
                   6806:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6807:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6808:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6809:      }
                   6810:      /* Period (stable) prevalence in each health state */
                   6811:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6812:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6813: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6814:      }
                   6815:      if(backcast==1){
                   6816:        /* Period (stable) back prevalence in each health state */
                   6817:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6818:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6819: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6820:        }
1.217     brouard  6821:      }
1.222     brouard  6822:      if(prevfcast==1){
                   6823:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6824:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6825:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6826: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6827:        }
                   6828:      }
1.268     brouard  6829:      if(backcast==1){
                   6830:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6831:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6832:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6833:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6834:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6835: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6836:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6837:        }
                   6838:      }
1.220     brouard  6839:         
1.222     brouard  6840:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6841:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6842: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6843:      }
                   6844:      /* } /\* end i1 *\/ */
                   6845:    }/* End k1 */
                   6846:    fprintf(fichtm,"</ul>");
1.126     brouard  6847: 
1.222     brouard  6848:    fprintf(fichtm,"\
1.126     brouard  6849: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6850:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6851:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6852: But because parameters are usually highly correlated (a higher incidence of disability \
                   6853: and a higher incidence of recovery can give very close observed transition) it might \
                   6854: be very useful to look not only at linear confidence intervals estimated from the \
                   6855: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6856: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6857: covariance matrix of the one-step probabilities. \
                   6858: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6859: 
1.222     brouard  6860:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6861:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6862:    fprintf(fichtm,"\
1.126     brouard  6863:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6864:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6865: 
1.222     brouard  6866:    fprintf(fichtm,"\
1.126     brouard  6867:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6868:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6869:    fprintf(fichtm,"\
1.126     brouard  6870:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6871:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6872:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6873:    fprintf(fichtm,"\
1.126     brouard  6874:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6875:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6876:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6877:    fprintf(fichtm,"\
1.128     brouard  6878:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6879:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6880:    fprintf(fichtm,"\
1.128     brouard  6881:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6882:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6883:    fprintf(fichtm,"\
1.126     brouard  6884:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6885:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6886: 
                   6887: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6888: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6889: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6890: /*     <br>",fileres,fileres,fileres,fileres); */
                   6891: /*  else  */
                   6892: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6893:    fflush(fichtm);
                   6894:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6895: 
1.225     brouard  6896:    m=pow(2,cptcoveff);
1.222     brouard  6897:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6898: 
1.222     brouard  6899:    jj1=0;
1.237     brouard  6900: 
1.241     brouard  6901:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6902:    for(k1=1; k1<=m;k1++){
1.253     brouard  6903:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6904:        continue;
1.222     brouard  6905:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6906:      jj1++;
1.126     brouard  6907:      if (cptcovn > 0) {
                   6908:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6909:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6910:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6911:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6912:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6913:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6914:       }
                   6915: 
1.126     brouard  6916:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6917: 
1.222     brouard  6918:        if(invalidvarcomb[k1]){
                   6919:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6920:         continue;
                   6921:        }
1.126     brouard  6922:      }
                   6923:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6924:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6925: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6926: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6927:      }
                   6928:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6929: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6930: true period expectancies (those weighted with period prevalences are also\
                   6931:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6932:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6933: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6934:      /* } /\* end i1 *\/ */
                   6935:    }/* End k1 */
1.241     brouard  6936:   }/* End nres */
1.222     brouard  6937:    fprintf(fichtm,"</ul>");
                   6938:    fflush(fichtm);
1.126     brouard  6939: }
                   6940: 
                   6941: /******************* Gnuplot file **************/
1.270     brouard  6942: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6943: 
                   6944:   char dirfileres[132],optfileres[132];
1.264     brouard  6945:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6946:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6947:   int lv=0, vlv=0, kl=0;
1.130     brouard  6948:   int ng=0;
1.201     brouard  6949:   int vpopbased;
1.223     brouard  6950:   int ioffset; /* variable offset for columns */
1.270     brouard  6951:   int iyearc=1; /* variable column for year of projection  */
                   6952:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  6953:   int nres=0; /* Index of resultline */
1.266     brouard  6954:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6955: 
1.126     brouard  6956: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6957: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6958: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6959: /*   } */
                   6960: 
                   6961:   /*#ifdef windows */
                   6962:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6963:   /*#endif */
1.225     brouard  6964:   m=pow(2,cptcoveff);
1.126     brouard  6965: 
1.274   ! brouard  6966:   /* diagram of the model */
        !          6967:   fprintf(ficgp,"\n#Diagram of the model \n");
        !          6968:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
        !          6969:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
        !          6970:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
        !          6971: 
        !          6972:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
        !          6973:   fprintf(ficgp,"\n#show arrow\nunset label\n");
        !          6974:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
        !          6975:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
        !          6976:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
        !          6977:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
        !          6978:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
        !          6979: 
1.202     brouard  6980:   /* Contribution to likelihood */
                   6981:   /* Plot the probability implied in the likelihood */
1.223     brouard  6982:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6983:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6984:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6985:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6986: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6987:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6988: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6989:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6990:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6991:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6992:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6993:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6994:   for (i=1; i<= nlstate ; i ++) {
                   6995:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6996:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6997:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6998:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6999:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7000:     }
                   7001:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7002:   }
                   7003:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7004:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7005:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7006:   fprintf(ficgp,"\nset out;unset log\n");
                   7007:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7008: 
1.126     brouard  7009:   strcpy(dirfileres,optionfilefiname);
                   7010:   strcpy(optfileres,"vpl");
1.223     brouard  7011:   /* 1eme*/
1.238     brouard  7012:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7013:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7014:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7015:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7016:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7017:          continue;
                   7018:        /* We are interested in selected combination by the resultline */
1.246     brouard  7019:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7020:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7021:        strcpy(gplotlabel,"(");
1.238     brouard  7022:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7023:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7024:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7025:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7026:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7027:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7028:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7029:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7030:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7031:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7032:        }
                   7033:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7034:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7035:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7036:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7037:        }
                   7038:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7039:        /* printf("\n#\n"); */
1.238     brouard  7040:        fprintf(ficgp,"\n#\n");
                   7041:        if(invalidvarcomb[k1]){
1.260     brouard  7042:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7043:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7044:          continue;
                   7045:        }
1.235     brouard  7046:       
1.241     brouard  7047:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7048:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7049:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7050:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7051:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7052:       /* k1-1 error should be nres-1*/
1.238     brouard  7053:        for (i=1; i<= nlstate ; i ++) {
                   7054:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7055:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7056:        }
1.260     brouard  7057:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7058:        for (i=1; i<= nlstate ; i ++) {
                   7059:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7060:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7061:        } 
1.260     brouard  7062:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7063:        for (i=1; i<= nlstate ; i ++) {
                   7064:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7065:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7066:        }  
1.265     brouard  7067:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7068:        
                   7069:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7070:         if(cptcoveff ==0){
1.271     brouard  7071:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7072:        }else{
                   7073:          kl=0;
                   7074:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7075:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7076:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7077:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7078:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7079:            vlv= nbcode[Tvaraff[k]][lv];
                   7080:            kl++;
                   7081:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7082:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7083:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7084:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7085:            if(k==cptcoveff){
                   7086:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7087:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7088:            }else{
                   7089:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7090:              kl++;
                   7091:            }
                   7092:          } /* end covariate */
                   7093:        } /* end if no covariate */
                   7094: 
1.238     brouard  7095:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7096:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7097:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7098:          if(cptcoveff ==0){
1.245     brouard  7099:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7100:          }else{
                   7101:            kl=0;
                   7102:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7103:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7104:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7105:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7106:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7107:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7108:              kl++;
1.238     brouard  7109:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7110:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7111:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7112:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7113:              if(k==cptcoveff){
1.245     brouard  7114:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7115:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7116:              }else{
                   7117:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7118:                kl++;
                   7119:              }
                   7120:            } /* end covariate */
                   7121:          } /* end if no covariate */
1.268     brouard  7122:          if(backcast == 1){
                   7123:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7124:            /* k1-1 error should be nres-1*/
                   7125:            for (i=1; i<= nlstate ; i ++) {
                   7126:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7127:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7128:            }
1.271     brouard  7129:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7130:            for (i=1; i<= nlstate ; i ++) {
                   7131:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7132:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7133:            } 
1.272     brouard  7134:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 5,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7135:            for (i=1; i<= nlstate ; i ++) {
                   7136:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7137:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7138:            } 
1.274   ! brouard  7139:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7140:          } /* end if backprojcast */
1.238     brouard  7141:        } /* end if backcast */
1.264     brouard  7142:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7143:       } /* nres */
1.201     brouard  7144:     } /* k1 */
                   7145:   } /* cpt */
1.235     brouard  7146: 
                   7147:   
1.126     brouard  7148:   /*2 eme*/
1.238     brouard  7149:   for (k1=1; k1<= m ; k1 ++){  
                   7150:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7151:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7152:        continue;
                   7153:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7154:       strcpy(gplotlabel,"(");
1.238     brouard  7155:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7156:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7157:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7158:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7159:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7160:        vlv= nbcode[Tvaraff[k]][lv];
                   7161:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7162:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7163:       }
1.237     brouard  7164:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7165:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7166:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7167:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7168:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7169:       }
1.264     brouard  7170:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7171:       fprintf(ficgp,"\n#\n");
1.223     brouard  7172:       if(invalidvarcomb[k1]){
                   7173:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7174:        continue;
                   7175:       }
1.219     brouard  7176:                        
1.241     brouard  7177:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7178:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7179:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7180:        if(vpopbased==0){
1.238     brouard  7181:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7182:        }else
1.238     brouard  7183:          fprintf(ficgp,"\nreplot ");
                   7184:        for (i=1; i<= nlstate+1 ; i ++) {
                   7185:          k=2*i;
1.261     brouard  7186:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7187:          for (j=1; j<= nlstate+1 ; j ++) {
                   7188:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7189:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7190:          }   
                   7191:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7192:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7193:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7194:          for (j=1; j<= nlstate+1 ; j ++) {
                   7195:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7196:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7197:          }   
                   7198:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7199:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7200:          for (j=1; j<= nlstate+1 ; j ++) {
                   7201:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7202:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7203:          }   
                   7204:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7205:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7206:        } /* state */
                   7207:       } /* vpopbased */
1.264     brouard  7208:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7209:     } /* end nres */
                   7210:   } /* k1 end 2 eme*/
                   7211:        
                   7212:        
                   7213:   /*3eme*/
                   7214:   for (k1=1; k1<= m ; k1 ++){
                   7215:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7216:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7217:        continue;
                   7218: 
                   7219:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7220:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7221:        strcpy(gplotlabel,"(");
1.238     brouard  7222:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7223:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7224:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7225:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7226:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7227:          vlv= nbcode[Tvaraff[k]][lv];
                   7228:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7229:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7230:        }
                   7231:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7232:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7233:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7234:        }       
1.264     brouard  7235:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7236:        fprintf(ficgp,"\n#\n");
                   7237:        if(invalidvarcomb[k1]){
                   7238:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7239:          continue;
                   7240:        }
                   7241:                        
                   7242:        /*       k=2+nlstate*(2*cpt-2); */
                   7243:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7244:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7245:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7246:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7247: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7248:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7249:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7250:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7251:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7252:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7253:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7254:                                
1.238     brouard  7255:        */
                   7256:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7257:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7258:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7259:                                
1.238     brouard  7260:        } 
1.261     brouard  7261:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7262:       }
1.264     brouard  7263:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7264:     } /* end nres */
                   7265:   } /* end kl 3eme */
1.126     brouard  7266:   
1.223     brouard  7267:   /* 4eme */
1.201     brouard  7268:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7269:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7270:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7271:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7272:        continue;
1.238     brouard  7273:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7274:        strcpy(gplotlabel,"(");
1.238     brouard  7275:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7276:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7277:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7278:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7279:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7280:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7281:          vlv= nbcode[Tvaraff[k]][lv];
                   7282:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7283:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7284:        }
                   7285:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7286:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7287:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7288:        }       
1.264     brouard  7289:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7290:        fprintf(ficgp,"\n#\n");
                   7291:        if(invalidvarcomb[k1]){
                   7292:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7293:          continue;
1.223     brouard  7294:        }
1.238     brouard  7295:       
1.241     brouard  7296:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7297:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7298:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7299: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7300:        k=3;
                   7301:        for (i=1; i<= nlstate ; i ++){
                   7302:          if(i==1){
                   7303:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7304:          }else{
                   7305:            fprintf(ficgp,", '' ");
                   7306:          }
                   7307:          l=(nlstate+ndeath)*(i-1)+1;
                   7308:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7309:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7310:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7311:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7312:        } /* nlstate */
1.264     brouard  7313:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7314:       } /* end cpt state*/ 
                   7315:     } /* end nres */
                   7316:   } /* end covariate k1 */  
                   7317: 
1.220     brouard  7318: /* 5eme */
1.201     brouard  7319:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7320:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7321:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7322:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7323:        continue;
1.238     brouard  7324:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7325:        strcpy(gplotlabel,"(");
1.238     brouard  7326:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7327:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7328:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7329:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7330:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7331:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7332:          vlv= nbcode[Tvaraff[k]][lv];
                   7333:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7334:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7335:        }
                   7336:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7337:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7338:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7339:        }       
1.264     brouard  7340:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7341:        fprintf(ficgp,"\n#\n");
                   7342:        if(invalidvarcomb[k1]){
                   7343:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7344:          continue;
                   7345:        }
1.227     brouard  7346:       
1.241     brouard  7347:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7348:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7349:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7350: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7351:        k=3;
                   7352:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7353:          if(j==1)
                   7354:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7355:          else
                   7356:            fprintf(ficgp,", '' ");
                   7357:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7358:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7359:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7360:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7361:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7362:        } /* nlstate */
                   7363:        fprintf(ficgp,", '' ");
                   7364:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7365:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7366:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7367:          if(j < nlstate)
                   7368:            fprintf(ficgp,"$%d +",k+l);
                   7369:          else
                   7370:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7371:        }
1.264     brouard  7372:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7373:       } /* end cpt state*/ 
                   7374:     } /* end covariate */  
                   7375:   } /* end nres */
1.227     brouard  7376:   
1.220     brouard  7377: /* 6eme */
1.202     brouard  7378:   /* CV preval stable (period) for each covariate */
1.237     brouard  7379:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7380:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7381:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7382:       continue;
1.255     brouard  7383:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7384:       strcpy(gplotlabel,"(");      
1.211     brouard  7385:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7386:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7387:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7388:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7389:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7390:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7391:        vlv= nbcode[Tvaraff[k]][lv];
                   7392:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7393:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7394:       }
1.237     brouard  7395:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7396:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7397:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7398:       }        
1.264     brouard  7399:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7400:       fprintf(ficgp,"\n#\n");
1.223     brouard  7401:       if(invalidvarcomb[k1]){
1.227     brouard  7402:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7403:        continue;
1.223     brouard  7404:       }
1.227     brouard  7405:       
1.241     brouard  7406:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7407:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7408:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7409: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7410:       k=3; /* Offset */
1.255     brouard  7411:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7412:        if(i==1)
                   7413:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7414:        else
                   7415:          fprintf(ficgp,", '' ");
1.255     brouard  7416:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7417:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7418:        for (j=2; j<= nlstate ; j ++)
                   7419:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7420:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7421:       } /* nlstate */
1.264     brouard  7422:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7423:     } /* end cpt state*/ 
                   7424:   } /* end covariate */  
1.227     brouard  7425:   
                   7426:   
1.220     brouard  7427: /* 7eme */
1.218     brouard  7428:   if(backcast == 1){
1.217     brouard  7429:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7430:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7431:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7432:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7433:        continue;
1.268     brouard  7434:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7435:        strcpy(gplotlabel,"(");      
                   7436:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7437:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7438:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7439:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7440:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7441:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7442:          vlv= nbcode[Tvaraff[k]][lv];
                   7443:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7444:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7445:        }
1.237     brouard  7446:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7447:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7448:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7449:        }       
1.264     brouard  7450:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7451:        fprintf(ficgp,"\n#\n");
                   7452:        if(invalidvarcomb[k1]){
                   7453:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7454:          continue;
                   7455:        }
                   7456:        
1.241     brouard  7457:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7458:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7459:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7460: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7461:        k=3; /* Offset */
1.268     brouard  7462:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7463:          if(i==1)
                   7464:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7465:          else
                   7466:            fprintf(ficgp,", '' ");
                   7467:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7468:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7469:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7470:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7471:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7472:          /* for (j=2; j<= nlstate ; j ++) */
                   7473:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7474:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7475:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7476:        } /* nlstate */
1.264     brouard  7477:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7478:       } /* end cpt state*/ 
                   7479:     } /* end covariate */  
                   7480:   } /* End if backcast */
                   7481:   
1.223     brouard  7482:   /* 8eme */
1.218     brouard  7483:   if(prevfcast==1){
                   7484:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7485:     
1.237     brouard  7486:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7487:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7488:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7489:        continue;
1.211     brouard  7490:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7491:        strcpy(gplotlabel,"(");      
1.227     brouard  7492:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7493:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7494:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7495:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7496:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7497:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7498:          vlv= nbcode[Tvaraff[k]][lv];
                   7499:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7500:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7501:        }
1.237     brouard  7502:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7503:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7504:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7505:        }       
1.264     brouard  7506:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7507:        fprintf(ficgp,"\n#\n");
                   7508:        if(invalidvarcomb[k1]){
                   7509:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7510:          continue;
                   7511:        }
                   7512:        
                   7513:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7514:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7515:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7516:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7517: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7518: 
                   7519:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7520:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7521:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7522:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7523:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7524:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7525:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7526:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7527:          if(i==istart){
1.227     brouard  7528:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7529:          }else{
                   7530:            fprintf(ficgp,",\\\n '' ");
                   7531:          }
                   7532:          if(cptcoveff ==0){ /* No covariate */
                   7533:            ioffset=2; /* Age is in 2 */
                   7534:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7535:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7536:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7537:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7538:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7539:            if(i==nlstate+1){
1.270     brouard  7540:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7541:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7542:              fprintf(ficgp,",\\\n '' ");
                   7543:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7544:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7545:                     offyear,                           \
1.268     brouard  7546:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7547:            }else
1.227     brouard  7548:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7549:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7550:          }else{ /* more than 2 covariates */
1.270     brouard  7551:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7552:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7553:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7554:            iyearc=ioffset-1;
                   7555:            iagec=ioffset;
1.227     brouard  7556:            fprintf(ficgp," u %d:(",ioffset); 
                   7557:            kl=0;
                   7558:            strcpy(gplotcondition,"(");
                   7559:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7560:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7561:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7562:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7563:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7564:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7565:              kl++;
                   7566:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7567:              kl++;
                   7568:              if(k <cptcoveff && cptcoveff>1)
                   7569:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7570:            }
                   7571:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7572:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7573:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7574:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7575:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7576:            if(i==nlstate+1){
1.270     brouard  7577:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7578:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7579:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7580:              fprintf(ficgp," u %d:(",iagec); 
                   7581:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7582:                      iyearc, iagec, offyear,                           \
                   7583:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7584: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7585:            }else{
                   7586:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7587:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7588:            }
                   7589:          } /* end if covariate */
                   7590:        } /* nlstate */
1.264     brouard  7591:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7592:       } /* end cpt state*/
                   7593:     } /* end covariate */
                   7594:   } /* End if prevfcast */
1.227     brouard  7595:   
1.268     brouard  7596:   if(backcast==1){
                   7597:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7598:     
                   7599:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7600:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7601:       if(m != 1 && TKresult[nres]!= k1)
                   7602:        continue;
                   7603:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7604:        strcpy(gplotlabel,"(");      
                   7605:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7606:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7607:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7608:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7609:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7610:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7611:          vlv= nbcode[Tvaraff[k]][lv];
                   7612:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7613:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7614:        }
                   7615:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7616:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7617:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7618:        }       
                   7619:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7620:        fprintf(ficgp,"\n#\n");
                   7621:        if(invalidvarcomb[k1]){
                   7622:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7623:          continue;
                   7624:        }
                   7625:        
                   7626:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7627:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7628:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7629:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7630: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7631: 
                   7632:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7633:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7634:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7635:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7636:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7637:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7638:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7639:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7640:          if(i==istart){
                   7641:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7642:          }else{
                   7643:            fprintf(ficgp,",\\\n '' ");
                   7644:          }
                   7645:          if(cptcoveff ==0){ /* No covariate */
                   7646:            ioffset=2; /* Age is in 2 */
                   7647:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7648:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7649:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7650:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7651:            fprintf(ficgp," u %d:(", ioffset); 
                   7652:            if(i==nlstate+1){
1.270     brouard  7653:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7654:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7655:              fprintf(ficgp,",\\\n '' ");
                   7656:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7657:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7658:                     offbyear,                          \
                   7659:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7660:            }else
                   7661:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7662:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7663:          }else{ /* more than 2 covariates */
1.270     brouard  7664:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7665:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7666:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7667:            iyearc=ioffset-1;
                   7668:            iagec=ioffset;
1.268     brouard  7669:            fprintf(ficgp," u %d:(",ioffset); 
                   7670:            kl=0;
                   7671:            strcpy(gplotcondition,"(");
                   7672:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7673:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7674:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7675:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7676:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7677:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7678:              kl++;
                   7679:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7680:              kl++;
                   7681:              if(k <cptcoveff && cptcoveff>1)
                   7682:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7683:            }
                   7684:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7685:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7686:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7687:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7688:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7689:            if(i==nlstate+1){
1.270     brouard  7690:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7691:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7692:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7693:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7694:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7695:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7696:                      iyearc,iagec,offbyear,                            \
                   7697:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7698: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7699:            }else{
                   7700:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7701:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7702:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7703:            }
                   7704:          } /* end if covariate */
                   7705:        } /* nlstate */
                   7706:        fprintf(ficgp,"\nset out; unset label;\n");
                   7707:       } /* end cpt state*/
                   7708:     } /* end covariate */
                   7709:   } /* End if backcast */
                   7710:   
1.227     brouard  7711:   
1.238     brouard  7712:   /* 9eme writing MLE parameters */
                   7713:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7714:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7715:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7716:     for(k=1; k <=(nlstate+ndeath); k++){
                   7717:       if (k != i) {
1.227     brouard  7718:        fprintf(ficgp,"#   current state %d\n",k);
                   7719:        for(j=1; j <=ncovmodel; j++){
                   7720:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7721:          jk++; 
                   7722:        }
                   7723:        fprintf(ficgp,"\n");
1.126     brouard  7724:       }
                   7725:     }
1.223     brouard  7726:   }
1.187     brouard  7727:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7728:   
1.145     brouard  7729:   /*goto avoid;*/
1.238     brouard  7730:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7731:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7732:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7733:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7734:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7735:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7736:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7737:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7738:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7739:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7740:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7741:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7742:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7743:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7744:   fprintf(ficgp,"#\n");
1.223     brouard  7745:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7746:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7747:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7748:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7749:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7750:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7751:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7752:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7753:        continue;
1.264     brouard  7754:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7755:       strcpy(gplotlabel,"(");
                   7756:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7757:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7758:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7759:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7760:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7761:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7762:        vlv= nbcode[Tvaraff[k]][lv];
                   7763:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7764:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7765:       }
1.237     brouard  7766:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7767:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7768:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7769:       }        
1.264     brouard  7770:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7771:       fprintf(ficgp,"\n#\n");
1.264     brouard  7772:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7773:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7774:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7775:       if (ng==1){
                   7776:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7777:        fprintf(ficgp,"\nunset log y");
                   7778:       }else if (ng==2){
                   7779:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7780:        fprintf(ficgp,"\nset log y");
                   7781:       }else if (ng==3){
                   7782:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7783:        fprintf(ficgp,"\nset log y");
                   7784:       }else
                   7785:        fprintf(ficgp,"\nunset title ");
                   7786:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7787:       i=1;
                   7788:       for(k2=1; k2<=nlstate; k2++) {
                   7789:        k3=i;
                   7790:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7791:          if (k != k2){
                   7792:            switch( ng) {
                   7793:            case 1:
                   7794:              if(nagesqr==0)
                   7795:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7796:              else /* nagesqr =1 */
                   7797:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7798:              break;
                   7799:            case 2: /* ng=2 */
                   7800:              if(nagesqr==0)
                   7801:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7802:              else /* nagesqr =1 */
                   7803:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7804:              break;
                   7805:            case 3:
                   7806:              if(nagesqr==0)
                   7807:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7808:              else /* nagesqr =1 */
                   7809:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7810:              break;
                   7811:            }
                   7812:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7813:            ijp=1; /* product no age */
                   7814:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7815:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7816:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7817:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7818:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7819:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7820:                    if(DummyV[j]==0){
                   7821:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7822:                    }else{ /* quantitative */
                   7823:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7824:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7825:                    }
                   7826:                    ij++;
1.237     brouard  7827:                  }
1.268     brouard  7828:                } 
                   7829:              }else if(cptcovprod >0){
                   7830:                if(j==Tprod[ijp]) { /* */ 
                   7831:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7832:                  if(ijp <=cptcovprod) { /* Product */
                   7833:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7834:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7835:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7836:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7837:                      }else{ /* Vn is dummy and Vm is quanti */
                   7838:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7839:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7840:                      }
                   7841:                    }else{ /* Vn*Vm Vn is quanti */
                   7842:                      if(DummyV[Tvard[ijp][2]]==0){
                   7843:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7844:                      }else{ /* Both quanti */
                   7845:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7846:                      }
1.237     brouard  7847:                    }
1.268     brouard  7848:                    ijp++;
1.237     brouard  7849:                  }
1.268     brouard  7850:                } /* end Tprod */
1.237     brouard  7851:              } else{  /* simple covariate */
1.264     brouard  7852:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7853:                if(Dummy[j]==0){
                   7854:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7855:                }else{ /* quantitative */
                   7856:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7857:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7858:                }
1.237     brouard  7859:              } /* end simple */
                   7860:            } /* end j */
1.223     brouard  7861:          }else{
                   7862:            i=i-ncovmodel;
                   7863:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7864:              fprintf(ficgp," (1.");
                   7865:          }
1.227     brouard  7866:          
1.223     brouard  7867:          if(ng != 1){
                   7868:            fprintf(ficgp,")/(1");
1.227     brouard  7869:            
1.264     brouard  7870:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7871:              if(nagesqr==0)
1.264     brouard  7872:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7873:              else /* nagesqr =1 */
1.264     brouard  7874:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7875:               
1.223     brouard  7876:              ij=1;
                   7877:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7878:                 if(cptcovage >0){ 
                   7879:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7880:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7881:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7882:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7883:                       ij++;
                   7884:                     }
                   7885:                   }
                   7886:                 }else
                   7887:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7888:              }
                   7889:              fprintf(ficgp,")");
                   7890:            }
                   7891:            fprintf(ficgp,")");
                   7892:            if(ng ==2)
                   7893:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7894:            else /* ng= 3 */
                   7895:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7896:          }else{ /* end ng <> 1 */
                   7897:            if( k !=k2) /* logit p11 is hard to draw */
                   7898:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7899:          }
                   7900:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7901:            fprintf(ficgp,",");
                   7902:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7903:            fprintf(ficgp,",");
                   7904:          i=i+ncovmodel;
                   7905:        } /* end k */
                   7906:       } /* end k2 */
1.264     brouard  7907:       fprintf(ficgp,"\n set out; unset label;\n");
                   7908:     } /* end k1 */
1.223     brouard  7909:   } /* end ng */
                   7910:   /* avoid: */
                   7911:   fflush(ficgp); 
1.126     brouard  7912: }  /* end gnuplot */
                   7913: 
                   7914: 
                   7915: /*************** Moving average **************/
1.219     brouard  7916: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7917:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7918:    
1.222     brouard  7919:    int i, cpt, cptcod;
                   7920:    int modcovmax =1;
                   7921:    int mobilavrange, mob;
                   7922:    int iage=0;
                   7923: 
1.266     brouard  7924:    double sum=0., sumr=0.;
1.222     brouard  7925:    double age;
1.266     brouard  7926:    double *sumnewp, *sumnewm, *sumnewmr;
                   7927:    double *agemingood, *agemaxgood; 
                   7928:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7929:   
                   7930:   
1.225     brouard  7931:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7932:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7933: 
                   7934:    sumnewp = vector(1,ncovcombmax);
                   7935:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7936:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7937:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7938:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7939:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7940:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7941: 
                   7942:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7943:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7944:      sumnewp[cptcod]=0.;
1.266     brouard  7945:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7946:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7947:    }
                   7948:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7949:   
1.266     brouard  7950:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7951:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7952:      else mobilavrange=mobilav;
                   7953:      for (age=bage; age<=fage; age++)
                   7954:        for (i=1; i<=nlstate;i++)
                   7955:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7956:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7957:      /* We keep the original values on the extreme ages bage, fage and for 
                   7958:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7959:        we use a 5 terms etc. until the borders are no more concerned. 
                   7960:      */ 
                   7961:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7962:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7963:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7964:           sumnewm[cptcod]=0.;
                   7965:           for (i=1; i<=nlstate;i++){
1.222     brouard  7966:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7967:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7968:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7969:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7970:             }
                   7971:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7972:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7973:           } /* end i */
                   7974:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7975:         } /* end cptcod */
1.222     brouard  7976:        }/* end age */
                   7977:      }/* end mob */
1.266     brouard  7978:    }else{
                   7979:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7980:      return -1;
1.266     brouard  7981:    }
                   7982: 
                   7983:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7984:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7985:      if(invalidvarcomb[cptcod]){
                   7986:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7987:        continue;
                   7988:      }
1.219     brouard  7989: 
1.266     brouard  7990:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7991:        sumnewm[cptcod]=0.;
                   7992:        sumnewmr[cptcod]=0.;
                   7993:        for (i=1; i<=nlstate;i++){
                   7994:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7995:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7996:        }
                   7997:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7998:         agemingoodr[cptcod]=age;
                   7999:        }
                   8000:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8001:           agemingood[cptcod]=age;
                   8002:        }
                   8003:      } /* age */
                   8004:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8005:        sumnewm[cptcod]=0.;
1.266     brouard  8006:        sumnewmr[cptcod]=0.;
1.222     brouard  8007:        for (i=1; i<=nlstate;i++){
                   8008:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8009:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8010:        }
                   8011:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8012:         agemaxgoodr[cptcod]=age;
1.222     brouard  8013:        }
                   8014:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8015:         agemaxgood[cptcod]=age;
                   8016:        }
                   8017:      } /* age */
                   8018:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8019:      /* but they will change */
                   8020:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8021:        sumnewm[cptcod]=0.;
                   8022:        sumnewmr[cptcod]=0.;
                   8023:        for (i=1; i<=nlstate;i++){
                   8024:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8025:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8026:        }
                   8027:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8028:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8029:           agemaxgoodr[cptcod]=age;  /* age min */
                   8030:           for (i=1; i<=nlstate;i++)
                   8031:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8032:         }else{ /* bad we change the value with the values of good ages */
                   8033:           for (i=1; i<=nlstate;i++){
                   8034:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8035:           } /* i */
                   8036:         } /* end bad */
                   8037:        }else{
                   8038:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8039:           agemaxgood[cptcod]=age;
                   8040:         }else{ /* bad we change the value with the values of good ages */
                   8041:           for (i=1; i<=nlstate;i++){
                   8042:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8043:           } /* i */
                   8044:         } /* end bad */
                   8045:        }/* end else */
                   8046:        sum=0.;sumr=0.;
                   8047:        for (i=1; i<=nlstate;i++){
                   8048:         sum+=mobaverage[(int)age][i][cptcod];
                   8049:         sumr+=probs[(int)age][i][cptcod];
                   8050:        }
                   8051:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8052:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8053:        } /* end bad */
                   8054:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8055:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8056:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8057:        } /* end bad */
                   8058:      }/* age */
1.266     brouard  8059: 
                   8060:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8061:        sumnewm[cptcod]=0.;
1.266     brouard  8062:        sumnewmr[cptcod]=0.;
1.222     brouard  8063:        for (i=1; i<=nlstate;i++){
                   8064:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8065:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8066:        } 
                   8067:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8068:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8069:           agemingoodr[cptcod]=age;
                   8070:           for (i=1; i<=nlstate;i++)
                   8071:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8072:         }else{ /* bad we change the value with the values of good ages */
                   8073:           for (i=1; i<=nlstate;i++){
                   8074:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8075:           } /* i */
                   8076:         } /* end bad */
                   8077:        }else{
                   8078:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8079:           agemingood[cptcod]=age;
                   8080:         }else{ /* bad */
                   8081:           for (i=1; i<=nlstate;i++){
                   8082:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8083:           } /* i */
                   8084:         } /* end bad */
                   8085:        }/* end else */
                   8086:        sum=0.;sumr=0.;
                   8087:        for (i=1; i<=nlstate;i++){
                   8088:         sum+=mobaverage[(int)age][i][cptcod];
                   8089:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8090:        }
1.266     brouard  8091:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8092:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8093:        } /* end bad */
                   8094:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8095:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8096:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8097:        } /* end bad */
                   8098:      }/* age */
1.266     brouard  8099: 
1.222     brouard  8100:                
                   8101:      for (age=bage; age<=fage; age++){
1.235     brouard  8102:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8103:        sumnewp[cptcod]=0.;
                   8104:        sumnewm[cptcod]=0.;
                   8105:        for (i=1; i<=nlstate;i++){
                   8106:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8107:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8108:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8109:        }
                   8110:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8111:      }
                   8112:      /* printf("\n"); */
                   8113:      /* } */
1.266     brouard  8114: 
1.222     brouard  8115:      /* brutal averaging */
1.266     brouard  8116:      /* for (i=1; i<=nlstate;i++){ */
                   8117:      /*   for (age=1; age<=bage; age++){ */
                   8118:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8119:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8120:      /*   }     */
                   8121:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8122:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8123:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8124:      /*   } */
                   8125:      /* } /\* end i status *\/ */
                   8126:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8127:      /*   for (age=1; age<=AGESUP; age++){ */
                   8128:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8129:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8130:      /*   } */
                   8131:      /* } */
1.222     brouard  8132:    }/* end cptcod */
1.266     brouard  8133:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8134:    free_vector(agemaxgood,1, ncovcombmax);
                   8135:    free_vector(agemingood,1, ncovcombmax);
                   8136:    free_vector(agemingoodr,1, ncovcombmax);
                   8137:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8138:    free_vector(sumnewm,1, ncovcombmax);
                   8139:    free_vector(sumnewp,1, ncovcombmax);
                   8140:    return 0;
                   8141:  }/* End movingaverage */
1.218     brouard  8142:  
1.126     brouard  8143: 
                   8144: /************** Forecasting ******************/
1.269     brouard  8145:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8146:   /* proj1, year, month, day of starting projection 
                   8147:      agemin, agemax range of age
                   8148:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8149:      anproj2 year of en of projection (same day and month as proj1).
                   8150:   */
1.267     brouard  8151:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8152:   double agec; /* generic age */
                   8153:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8154:   double *popeffectif,*popcount;
                   8155:   double ***p3mat;
1.218     brouard  8156:   /* double ***mobaverage; */
1.126     brouard  8157:   char fileresf[FILENAMELENGTH];
                   8158: 
                   8159:   agelim=AGESUP;
1.211     brouard  8160:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8161:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8162:      We still use firstpass and lastpass as another selection.
                   8163:   */
1.214     brouard  8164:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8165:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8166:  
1.201     brouard  8167:   strcpy(fileresf,"F_"); 
                   8168:   strcat(fileresf,fileresu);
1.126     brouard  8169:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8170:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8171:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8172:   }
1.235     brouard  8173:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8174:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8175: 
1.225     brouard  8176:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8177: 
                   8178: 
                   8179:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8180:   if (stepm<=12) stepsize=1;
                   8181:   if(estepm < stepm){
                   8182:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8183:   }
1.270     brouard  8184:   else{
                   8185:     hstepm=estepm;   
                   8186:   }
                   8187:   if(estepm > stepm){ /* Yes every two year */
                   8188:     stepsize=2;
                   8189:   }
1.126     brouard  8190: 
                   8191:   hstepm=hstepm/stepm; 
                   8192:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8193:                                fractional in yp1 */
                   8194:   anprojmean=yp;
                   8195:   yp2=modf((yp1*12),&yp);
                   8196:   mprojmean=yp;
                   8197:   yp1=modf((yp2*30.5),&yp);
                   8198:   jprojmean=yp;
                   8199:   if(jprojmean==0) jprojmean=1;
                   8200:   if(mprojmean==0) jprojmean=1;
                   8201: 
1.227     brouard  8202:   i1=pow(2,cptcoveff);
1.126     brouard  8203:   if (cptcovn < 1){i1=1;}
                   8204:   
                   8205:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8206:   
                   8207:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8208:   
1.126     brouard  8209: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8210:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8211:   for(k=1; k<=i1;k++){
1.253     brouard  8212:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8213:       continue;
1.227     brouard  8214:     if(invalidvarcomb[k]){
                   8215:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8216:       continue;
                   8217:     }
                   8218:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8219:     for(j=1;j<=cptcoveff;j++) {
                   8220:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8221:     }
1.235     brouard  8222:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8223:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8224:     }
1.227     brouard  8225:     fprintf(ficresf," yearproj age");
                   8226:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8227:       for(i=1; i<=nlstate;i++)               
                   8228:        fprintf(ficresf," p%d%d",i,j);
                   8229:       fprintf(ficresf," wp.%d",j);
                   8230:     }
                   8231:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8232:       fprintf(ficresf,"\n");
                   8233:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8234:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8235:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8236:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8237:        nhstepm = nhstepm/hstepm; 
                   8238:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8239:        oldm=oldms;savm=savms;
1.268     brouard  8240:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8241:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8242:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8243:        for (h=0; h<=nhstepm; h++){
                   8244:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8245:            break;
                   8246:          }
                   8247:        }
                   8248:        fprintf(ficresf,"\n");
                   8249:        for(j=1;j<=cptcoveff;j++) 
                   8250:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8251:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8252:        
                   8253:        for(j=1; j<=nlstate+ndeath;j++) {
                   8254:          ppij=0.;
                   8255:          for(i=1; i<=nlstate;i++) {
                   8256:            /* if (mobilav>=1)  */
1.269     brouard  8257:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8258:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8259:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8260:            /* } */
                   8261:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8262:          } /* end i */
                   8263:          fprintf(ficresf," %.3f", ppij);
                   8264:        }/* end j */
1.227     brouard  8265:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8266:       } /* end agec */
1.266     brouard  8267:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8268:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8269:     } /* end yearp */
                   8270:   } /* end  k */
1.219     brouard  8271:        
1.126     brouard  8272:   fclose(ficresf);
1.215     brouard  8273:   printf("End of Computing forecasting \n");
                   8274:   fprintf(ficlog,"End of Computing forecasting\n");
                   8275: 
1.126     brouard  8276: }
                   8277: 
1.269     brouard  8278: /************** Back Forecasting ******************/
                   8279:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8280:   /* back1, year, month, day of starting backection
                   8281:      agemin, agemax range of age
                   8282:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8283:      anback2 year of end of backprojection (same day and month as back1).
                   8284:      prevacurrent and prev are prevalences.
1.267     brouard  8285:   */
                   8286:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8287:   double agec; /* generic age */
1.268     brouard  8288:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8289:   double *popeffectif,*popcount;
                   8290:   double ***p3mat;
                   8291:   /* double ***mobaverage; */
                   8292:   char fileresfb[FILENAMELENGTH];
                   8293:  
1.268     brouard  8294:   agelim=AGEINF;
1.267     brouard  8295:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8296:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8297:      We still use firstpass and lastpass as another selection.
                   8298:   */
                   8299:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8300:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8301: 
                   8302:   /*Do we need to compute prevalence again?*/
                   8303: 
                   8304:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8305:   
                   8306:   strcpy(fileresfb,"FB_");
                   8307:   strcat(fileresfb,fileresu);
                   8308:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8309:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8310:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8311:   }
                   8312:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8313:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8314:   
                   8315:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8316:   
                   8317:    
                   8318:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8319:   if (stepm<=12) stepsize=1;
                   8320:   if(estepm < stepm){
                   8321:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8322:   }
1.270     brouard  8323:   else{
                   8324:     hstepm=estepm;   
                   8325:   }
                   8326:   if(estepm >= stepm){ /* Yes every two year */
                   8327:     stepsize=2;
                   8328:   }
1.267     brouard  8329:   
                   8330:   hstepm=hstepm/stepm;
                   8331:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8332:                                fractional in yp1 */
                   8333:   anprojmean=yp;
                   8334:   yp2=modf((yp1*12),&yp);
                   8335:   mprojmean=yp;
                   8336:   yp1=modf((yp2*30.5),&yp);
                   8337:   jprojmean=yp;
                   8338:   if(jprojmean==0) jprojmean=1;
                   8339:   if(mprojmean==0) jprojmean=1;
                   8340:   
                   8341:   i1=pow(2,cptcoveff);
                   8342:   if (cptcovn < 1){i1=1;}
                   8343:   
                   8344:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8345:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8346:   
                   8347:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8348:   
                   8349:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8350:   for(k=1; k<=i1;k++){
                   8351:     if(i1 != 1 && TKresult[nres]!= k)
                   8352:       continue;
                   8353:     if(invalidvarcomb[k]){
                   8354:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8355:       continue;
                   8356:     }
1.268     brouard  8357:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8358:     for(j=1;j<=cptcoveff;j++) {
                   8359:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8360:     }
                   8361:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8362:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8363:     }
                   8364:     fprintf(ficresfb," yearbproj age");
                   8365:     for(j=1; j<=nlstate+ndeath;j++){
                   8366:       for(i=1; i<=nlstate;i++)
1.268     brouard  8367:        fprintf(ficresfb," b%d%d",i,j);
                   8368:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8369:     }
                   8370:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8371:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8372:       fprintf(ficresfb,"\n");
                   8373:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8374:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8375:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8376:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8377:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8378:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8379:        nhstepm = nhstepm/hstepm;
                   8380:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8381:        oldm=oldms;savm=savms;
1.268     brouard  8382:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8383:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8384:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8385:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8386:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8387:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8388:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8389:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8390:            break;
                   8391:          }
                   8392:        }
                   8393:        fprintf(ficresfb,"\n");
                   8394:        for(j=1;j<=cptcoveff;j++)
                   8395:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8396:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8397:        for(i=1; i<=nlstate+ndeath;i++) {
                   8398:          ppij=0.;ppi=0.;
                   8399:          for(j=1; j<=nlstate;j++) {
                   8400:            /* if (mobilav==1) */
1.269     brouard  8401:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8402:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8403:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8404:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8405:              /* else { */
                   8406:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8407:              /* } */
1.268     brouard  8408:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8409:          } /* end j */
                   8410:          if(ppi <0.99){
                   8411:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8412:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8413:          }
                   8414:          fprintf(ficresfb," %.3f", ppij);
                   8415:        }/* end j */
1.267     brouard  8416:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8417:       } /* end agec */
                   8418:     } /* end yearp */
                   8419:   } /* end k */
1.217     brouard  8420:   
1.267     brouard  8421:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8422:   
1.267     brouard  8423:   fclose(ficresfb);
                   8424:   printf("End of Computing Back forecasting \n");
                   8425:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8426:        
1.267     brouard  8427: }
1.217     brouard  8428: 
1.269     brouard  8429: /* Variance of prevalence limit: varprlim */
                   8430:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8431:     /*------- Variance of period (stable) prevalence------*/   
                   8432:  
                   8433:    char fileresvpl[FILENAMELENGTH];  
                   8434:    FILE *ficresvpl;
                   8435:    double **oldm, **savm;
                   8436:    double **varpl; /* Variances of prevalence limits by age */   
                   8437:    int i1, k, nres, j ;
                   8438:    
                   8439:     strcpy(fileresvpl,"VPL_");
                   8440:     strcat(fileresvpl,fileresu);
                   8441:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8442:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8443:       exit(0);
                   8444:     }
                   8445:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8446:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8447:     
                   8448:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8449:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8450:     
                   8451:     i1=pow(2,cptcoveff);
                   8452:     if (cptcovn < 1){i1=1;}
                   8453: 
                   8454:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8455:     for(k=1; k<=i1;k++){
                   8456:       if(i1 != 1 && TKresult[nres]!= k)
                   8457:        continue;
                   8458:       fprintf(ficresvpl,"\n#****** ");
                   8459:       printf("\n#****** ");
                   8460:       fprintf(ficlog,"\n#****** ");
                   8461:       for(j=1;j<=cptcoveff;j++) {
                   8462:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8463:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8464:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8465:       }
                   8466:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8467:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8468:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8469:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8470:       }        
                   8471:       fprintf(ficresvpl,"******\n");
                   8472:       printf("******\n");
                   8473:       fprintf(ficlog,"******\n");
                   8474:       
                   8475:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8476:       oldm=oldms;savm=savms;
                   8477:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8478:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8479:       /*}*/
                   8480:     }
                   8481:     
                   8482:     fclose(ficresvpl);
                   8483:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8484:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8485: 
                   8486:  }
                   8487: /* Variance of back prevalence: varbprlim */
                   8488:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8489:       /*------- Variance of back (stable) prevalence------*/
                   8490: 
                   8491:    char fileresvbl[FILENAMELENGTH];  
                   8492:    FILE  *ficresvbl;
                   8493: 
                   8494:    double **oldm, **savm;
                   8495:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8496:    int i1, k, nres, j ;
                   8497: 
                   8498:    strcpy(fileresvbl,"VBL_");
                   8499:    strcat(fileresvbl,fileresu);
                   8500:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8501:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8502:      exit(0);
                   8503:    }
                   8504:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8505:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8506:    
                   8507:    
                   8508:    i1=pow(2,cptcoveff);
                   8509:    if (cptcovn < 1){i1=1;}
                   8510:    
                   8511:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8512:      for(k=1; k<=i1;k++){
                   8513:        if(i1 != 1 && TKresult[nres]!= k)
                   8514:         continue;
                   8515:        fprintf(ficresvbl,"\n#****** ");
                   8516:        printf("\n#****** ");
                   8517:        fprintf(ficlog,"\n#****** ");
                   8518:        for(j=1;j<=cptcoveff;j++) {
                   8519:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8520:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8521:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8522:        }
                   8523:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8524:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8525:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8526:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8527:        }
                   8528:        fprintf(ficresvbl,"******\n");
                   8529:        printf("******\n");
                   8530:        fprintf(ficlog,"******\n");
                   8531:        
                   8532:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8533:        oldm=oldms;savm=savms;
                   8534:        
                   8535:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8536:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8537:        /*}*/
                   8538:      }
                   8539:    
                   8540:    fclose(ficresvbl);
                   8541:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8542:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8543: 
                   8544:  } /* End of varbprlim */
                   8545: 
1.126     brouard  8546: /************** Forecasting *****not tested NB*************/
1.227     brouard  8547: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8548:   
1.227     brouard  8549: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8550: /*   int *popage; */
                   8551: /*   double calagedatem, agelim, kk1, kk2; */
                   8552: /*   double *popeffectif,*popcount; */
                   8553: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8554: /*   /\* double ***mobaverage; *\/ */
                   8555: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8556: 
1.227     brouard  8557: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8558: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8559: /*   agelim=AGESUP; */
                   8560: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8561:   
1.227     brouard  8562: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8563:   
                   8564:   
1.227     brouard  8565: /*   strcpy(filerespop,"POP_");  */
                   8566: /*   strcat(filerespop,fileresu); */
                   8567: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8568: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8569: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8570: /*   } */
                   8571: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8572: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8573: 
1.227     brouard  8574: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8575: 
1.227     brouard  8576: /*   /\* if (mobilav!=0) { *\/ */
                   8577: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8578: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8579: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8580: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8581: /*   /\*   } *\/ */
                   8582: /*   /\* } *\/ */
1.126     brouard  8583: 
1.227     brouard  8584: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8585: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8586:   
1.227     brouard  8587: /*   agelim=AGESUP; */
1.126     brouard  8588:   
1.227     brouard  8589: /*   hstepm=1; */
                   8590: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8591:        
1.227     brouard  8592: /*   if (popforecast==1) { */
                   8593: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8594: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8595: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8596: /*     }  */
                   8597: /*     popage=ivector(0,AGESUP); */
                   8598: /*     popeffectif=vector(0,AGESUP); */
                   8599: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8600:     
1.227     brouard  8601: /*     i=1;    */
                   8602: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8603:     
1.227     brouard  8604: /*     imx=i; */
                   8605: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8606: /*   } */
1.218     brouard  8607:   
1.227     brouard  8608: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8609: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8610: /*       k=k+1; */
                   8611: /*       fprintf(ficrespop,"\n#******"); */
                   8612: /*       for(j=1;j<=cptcoveff;j++) { */
                   8613: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8614: /*       } */
                   8615: /*       fprintf(ficrespop,"******\n"); */
                   8616: /*       fprintf(ficrespop,"# Age"); */
                   8617: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8618: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8619:       
1.227     brouard  8620: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8621: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8622:        
1.227     brouard  8623: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8624: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8625: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8626:          
1.227     brouard  8627: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8628: /*       oldm=oldms;savm=savms; */
                   8629: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8630:          
1.227     brouard  8631: /*       for (h=0; h<=nhstepm; h++){ */
                   8632: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8633: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8634: /*         }  */
                   8635: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8636: /*           kk1=0.;kk2=0; */
                   8637: /*           for(i=1; i<=nlstate;i++) {               */
                   8638: /*             if (mobilav==1)  */
                   8639: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8640: /*             else { */
                   8641: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8642: /*             } */
                   8643: /*           } */
                   8644: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8645: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8646: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8647: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8648: /*           } */
                   8649: /*         } */
                   8650: /*         for(i=1; i<=nlstate;i++){ */
                   8651: /*           kk1=0.; */
                   8652: /*           for(j=1; j<=nlstate;j++){ */
                   8653: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8654: /*           } */
                   8655: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8656: /*         } */
1.218     brouard  8657:            
1.227     brouard  8658: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8659: /*           for(j=1; j<=nlstate;j++)  */
                   8660: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8661: /*       } */
                   8662: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8663: /*     } */
                   8664: /*       } */
1.218     brouard  8665:       
1.227     brouard  8666: /*       /\******\/ */
1.218     brouard  8667:       
1.227     brouard  8668: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8669: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8670: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8671: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8672: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8673:          
1.227     brouard  8674: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8675: /*       oldm=oldms;savm=savms; */
                   8676: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8677: /*       for (h=0; h<=nhstepm; h++){ */
                   8678: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8679: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8680: /*         }  */
                   8681: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8682: /*           kk1=0.;kk2=0; */
                   8683: /*           for(i=1; i<=nlstate;i++) {               */
                   8684: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8685: /*           } */
                   8686: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8687: /*         } */
                   8688: /*       } */
                   8689: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8690: /*     } */
                   8691: /*       } */
                   8692: /*     }  */
                   8693: /*   } */
1.218     brouard  8694:   
1.227     brouard  8695: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8696:   
1.227     brouard  8697: /*   if (popforecast==1) { */
                   8698: /*     free_ivector(popage,0,AGESUP); */
                   8699: /*     free_vector(popeffectif,0,AGESUP); */
                   8700: /*     free_vector(popcount,0,AGESUP); */
                   8701: /*   } */
                   8702: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8703: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8704: /*   fclose(ficrespop); */
                   8705: /* } /\* End of popforecast *\/ */
1.218     brouard  8706:  
1.126     brouard  8707: int fileappend(FILE *fichier, char *optionfich)
                   8708: {
                   8709:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8710:     printf("Problem with file: %s\n", optionfich);
                   8711:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8712:     return (0);
                   8713:   }
                   8714:   fflush(fichier);
                   8715:   return (1);
                   8716: }
                   8717: 
                   8718: 
                   8719: /**************** function prwizard **********************/
                   8720: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8721: {
                   8722: 
                   8723:   /* Wizard to print covariance matrix template */
                   8724: 
1.164     brouard  8725:   char ca[32], cb[32];
                   8726:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8727:   int numlinepar;
                   8728: 
                   8729:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8730:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8731:   for(i=1; i <=nlstate; i++){
                   8732:     jj=0;
                   8733:     for(j=1; j <=nlstate+ndeath; j++){
                   8734:       if(j==i) continue;
                   8735:       jj++;
                   8736:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8737:       printf("%1d%1d",i,j);
                   8738:       fprintf(ficparo,"%1d%1d",i,j);
                   8739:       for(k=1; k<=ncovmodel;k++){
                   8740:        /*        printf(" %lf",param[i][j][k]); */
                   8741:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8742:        printf(" 0.");
                   8743:        fprintf(ficparo," 0.");
                   8744:       }
                   8745:       printf("\n");
                   8746:       fprintf(ficparo,"\n");
                   8747:     }
                   8748:   }
                   8749:   printf("# Scales (for hessian or gradient estimation)\n");
                   8750:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8751:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8752:   for(i=1; i <=nlstate; i++){
                   8753:     jj=0;
                   8754:     for(j=1; j <=nlstate+ndeath; j++){
                   8755:       if(j==i) continue;
                   8756:       jj++;
                   8757:       fprintf(ficparo,"%1d%1d",i,j);
                   8758:       printf("%1d%1d",i,j);
                   8759:       fflush(stdout);
                   8760:       for(k=1; k<=ncovmodel;k++){
                   8761:        /*      printf(" %le",delti3[i][j][k]); */
                   8762:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8763:        printf(" 0.");
                   8764:        fprintf(ficparo," 0.");
                   8765:       }
                   8766:       numlinepar++;
                   8767:       printf("\n");
                   8768:       fprintf(ficparo,"\n");
                   8769:     }
                   8770:   }
                   8771:   printf("# Covariance matrix\n");
                   8772: /* # 121 Var(a12)\n\ */
                   8773: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8774: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8775: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8776: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8777: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8778: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8779: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8780:   fflush(stdout);
                   8781:   fprintf(ficparo,"# Covariance matrix\n");
                   8782:   /* # 121 Var(a12)\n\ */
                   8783:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8784:   /* #   ...\n\ */
                   8785:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8786:   
                   8787:   for(itimes=1;itimes<=2;itimes++){
                   8788:     jj=0;
                   8789:     for(i=1; i <=nlstate; i++){
                   8790:       for(j=1; j <=nlstate+ndeath; j++){
                   8791:        if(j==i) continue;
                   8792:        for(k=1; k<=ncovmodel;k++){
                   8793:          jj++;
                   8794:          ca[0]= k+'a'-1;ca[1]='\0';
                   8795:          if(itimes==1){
                   8796:            printf("#%1d%1d%d",i,j,k);
                   8797:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8798:          }else{
                   8799:            printf("%1d%1d%d",i,j,k);
                   8800:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8801:            /*  printf(" %.5le",matcov[i][j]); */
                   8802:          }
                   8803:          ll=0;
                   8804:          for(li=1;li <=nlstate; li++){
                   8805:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8806:              if(lj==li) continue;
                   8807:              for(lk=1;lk<=ncovmodel;lk++){
                   8808:                ll++;
                   8809:                if(ll<=jj){
                   8810:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8811:                  if(ll<jj){
                   8812:                    if(itimes==1){
                   8813:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8814:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8815:                    }else{
                   8816:                      printf(" 0.");
                   8817:                      fprintf(ficparo," 0.");
                   8818:                    }
                   8819:                  }else{
                   8820:                    if(itimes==1){
                   8821:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8822:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8823:                    }else{
                   8824:                      printf(" 0.");
                   8825:                      fprintf(ficparo," 0.");
                   8826:                    }
                   8827:                  }
                   8828:                }
                   8829:              } /* end lk */
                   8830:            } /* end lj */
                   8831:          } /* end li */
                   8832:          printf("\n");
                   8833:          fprintf(ficparo,"\n");
                   8834:          numlinepar++;
                   8835:        } /* end k*/
                   8836:       } /*end j */
                   8837:     } /* end i */
                   8838:   } /* end itimes */
                   8839: 
                   8840: } /* end of prwizard */
                   8841: /******************* Gompertz Likelihood ******************************/
                   8842: double gompertz(double x[])
                   8843: { 
                   8844:   double A,B,L=0.0,sump=0.,num=0.;
                   8845:   int i,n=0; /* n is the size of the sample */
                   8846: 
1.220     brouard  8847:   for (i=1;i<=imx ; i++) {
1.126     brouard  8848:     sump=sump+weight[i];
                   8849:     /*    sump=sump+1;*/
                   8850:     num=num+1;
                   8851:   }
                   8852:  
                   8853:  
                   8854:   /* for (i=0; i<=imx; i++) 
                   8855:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8856: 
                   8857:   for (i=1;i<=imx ; i++)
                   8858:     {
                   8859:       if (cens[i] == 1 && wav[i]>1)
                   8860:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8861:       
                   8862:       if (cens[i] == 0 && wav[i]>1)
                   8863:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8864:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8865:       
                   8866:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8867:       if (wav[i] > 1 ) { /* ??? */
                   8868:        L=L+A*weight[i];
                   8869:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8870:       }
                   8871:     }
                   8872: 
                   8873:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8874:  
                   8875:   return -2*L*num/sump;
                   8876: }
                   8877: 
1.136     brouard  8878: #ifdef GSL
                   8879: /******************* Gompertz_f Likelihood ******************************/
                   8880: double gompertz_f(const gsl_vector *v, void *params)
                   8881: { 
                   8882:   double A,B,LL=0.0,sump=0.,num=0.;
                   8883:   double *x= (double *) v->data;
                   8884:   int i,n=0; /* n is the size of the sample */
                   8885: 
                   8886:   for (i=0;i<=imx-1 ; i++) {
                   8887:     sump=sump+weight[i];
                   8888:     /*    sump=sump+1;*/
                   8889:     num=num+1;
                   8890:   }
                   8891:  
                   8892:  
                   8893:   /* for (i=0; i<=imx; i++) 
                   8894:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8895:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8896:   for (i=1;i<=imx ; i++)
                   8897:     {
                   8898:       if (cens[i] == 1 && wav[i]>1)
                   8899:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8900:       
                   8901:       if (cens[i] == 0 && wav[i]>1)
                   8902:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8903:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8904:       
                   8905:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8906:       if (wav[i] > 1 ) { /* ??? */
                   8907:        LL=LL+A*weight[i];
                   8908:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8909:       }
                   8910:     }
                   8911: 
                   8912:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8913:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8914:  
                   8915:   return -2*LL*num/sump;
                   8916: }
                   8917: #endif
                   8918: 
1.126     brouard  8919: /******************* Printing html file ***********/
1.201     brouard  8920: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8921:                  int lastpass, int stepm, int weightopt, char model[],\
                   8922:                  int imx,  double p[],double **matcov,double agemortsup){
                   8923:   int i,k;
                   8924: 
                   8925:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8926:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8927:   for (i=1;i<=2;i++) 
                   8928:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8929:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8930:   fprintf(fichtm,"</ul>");
                   8931: 
                   8932: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8933: 
                   8934:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8935: 
                   8936:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8937:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8938: 
                   8939:  
                   8940:   fflush(fichtm);
                   8941: }
                   8942: 
                   8943: /******************* Gnuplot file **************/
1.201     brouard  8944: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8945: 
                   8946:   char dirfileres[132],optfileres[132];
1.164     brouard  8947: 
1.126     brouard  8948:   int ng;
                   8949: 
                   8950: 
                   8951:   /*#ifdef windows */
                   8952:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8953:     /*#endif */
                   8954: 
                   8955: 
                   8956:   strcpy(dirfileres,optionfilefiname);
                   8957:   strcpy(optfileres,"vpl");
1.199     brouard  8958:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8959:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8960:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8961:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8962:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8963: 
                   8964: } 
                   8965: 
1.136     brouard  8966: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8967: {
1.126     brouard  8968: 
1.136     brouard  8969:   /*-------- data file ----------*/
                   8970:   FILE *fic;
                   8971:   char dummy[]="                         ";
1.240     brouard  8972:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8973:   int lstra;
1.136     brouard  8974:   int linei, month, year,iout;
                   8975:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8976:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8977:   char *stratrunc;
1.223     brouard  8978: 
1.240     brouard  8979:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8980:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8981: 
1.240     brouard  8982:   for(v=1; v <=ncovcol;v++){
                   8983:     DummyV[v]=0;
                   8984:     FixedV[v]=0;
                   8985:   }
                   8986:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8987:     DummyV[v]=1;
                   8988:     FixedV[v]=0;
                   8989:   }
                   8990:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8991:     DummyV[v]=0;
                   8992:     FixedV[v]=1;
                   8993:   }
                   8994:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8995:     DummyV[v]=1;
                   8996:     FixedV[v]=1;
                   8997:   }
                   8998:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8999:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9000:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9001:   }
1.126     brouard  9002: 
1.136     brouard  9003:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9004:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9005:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9006:   }
1.126     brouard  9007: 
1.136     brouard  9008:   i=1;
                   9009:   linei=0;
                   9010:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9011:     linei=linei+1;
                   9012:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9013:       if(line[j] == '\t')
                   9014:        line[j] = ' ';
                   9015:     }
                   9016:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9017:       ;
                   9018:     };
                   9019:     line[j+1]=0;  /* Trims blanks at end of line */
                   9020:     if(line[0]=='#'){
                   9021:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9022:       printf("Comment line\n%s\n",line);
                   9023:       continue;
                   9024:     }
                   9025:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9026:     strcpy(line, linetmp);
1.223     brouard  9027:     
                   9028:     /* Loops on waves */
                   9029:     for (j=maxwav;j>=1;j--){
                   9030:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9031:        cutv(stra, strb, line, ' '); 
                   9032:        if(strb[0]=='.') { /* Missing value */
                   9033:          lval=-1;
                   9034:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9035:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9036:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9037:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9038:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9039:            return 1;
                   9040:          }
                   9041:        }else{
                   9042:          errno=0;
                   9043:          /* what_kind_of_number(strb); */
                   9044:          dval=strtod(strb,&endptr); 
                   9045:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9046:          /* if(strb != endptr && *endptr == '\0') */
                   9047:          /*    dval=dlval; */
                   9048:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9049:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9050:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9051:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9052:            return 1;
                   9053:          }
                   9054:          cotqvar[j][iv][i]=dval; 
                   9055:          cotvar[j][ntv+iv][i]=dval; 
                   9056:        }
                   9057:        strcpy(line,stra);
1.223     brouard  9058:       }/* end loop ntqv */
1.225     brouard  9059:       
1.223     brouard  9060:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9061:        cutv(stra, strb, line, ' '); 
                   9062:        if(strb[0]=='.') { /* Missing value */
                   9063:          lval=-1;
                   9064:        }else{
                   9065:          errno=0;
                   9066:          lval=strtol(strb,&endptr,10); 
                   9067:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9068:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9069:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9070:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9071:            return 1;
                   9072:          }
                   9073:        }
                   9074:        if(lval <-1 || lval >1){
                   9075:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9076:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9077:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9078:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9079:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9080:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9081:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9082:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9083:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9084:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9085:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9086:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9087:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9088:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9089:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9090:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9091:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9092:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9093:          return 1;
                   9094:        }
                   9095:        cotvar[j][iv][i]=(double)(lval);
                   9096:        strcpy(line,stra);
1.223     brouard  9097:       }/* end loop ntv */
1.225     brouard  9098:       
1.223     brouard  9099:       /* Statuses  at wave */
1.137     brouard  9100:       cutv(stra, strb, line, ' '); 
1.223     brouard  9101:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9102:        lval=-1;
1.136     brouard  9103:       }else{
1.238     brouard  9104:        errno=0;
                   9105:        lval=strtol(strb,&endptr,10); 
                   9106:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9107:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9108:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9109:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9110:          return 1;
                   9111:        }
1.136     brouard  9112:       }
1.225     brouard  9113:       
1.136     brouard  9114:       s[j][i]=lval;
1.225     brouard  9115:       
1.223     brouard  9116:       /* Date of Interview */
1.136     brouard  9117:       strcpy(line,stra);
                   9118:       cutv(stra, strb,line,' ');
1.169     brouard  9119:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9120:       }
1.169     brouard  9121:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9122:        month=99;
                   9123:        year=9999;
1.136     brouard  9124:       }else{
1.225     brouard  9125:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9126:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9127:        return 1;
1.136     brouard  9128:       }
                   9129:       anint[j][i]= (double) year; 
                   9130:       mint[j][i]= (double)month; 
                   9131:       strcpy(line,stra);
1.223     brouard  9132:     } /* End loop on waves */
1.225     brouard  9133:     
1.223     brouard  9134:     /* Date of death */
1.136     brouard  9135:     cutv(stra, strb,line,' '); 
1.169     brouard  9136:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9137:     }
1.169     brouard  9138:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9139:       month=99;
                   9140:       year=9999;
                   9141:     }else{
1.141     brouard  9142:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9143:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9144:       return 1;
1.136     brouard  9145:     }
                   9146:     andc[i]=(double) year; 
                   9147:     moisdc[i]=(double) month; 
                   9148:     strcpy(line,stra);
                   9149:     
1.223     brouard  9150:     /* Date of birth */
1.136     brouard  9151:     cutv(stra, strb,line,' '); 
1.169     brouard  9152:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9153:     }
1.169     brouard  9154:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9155:       month=99;
                   9156:       year=9999;
                   9157:     }else{
1.141     brouard  9158:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9159:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9160:       return 1;
1.136     brouard  9161:     }
                   9162:     if (year==9999) {
1.141     brouard  9163:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9164:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9165:       return 1;
                   9166:       
1.136     brouard  9167:     }
                   9168:     annais[i]=(double)(year);
                   9169:     moisnais[i]=(double)(month); 
                   9170:     strcpy(line,stra);
1.225     brouard  9171:     
1.223     brouard  9172:     /* Sample weight */
1.136     brouard  9173:     cutv(stra, strb,line,' '); 
                   9174:     errno=0;
                   9175:     dval=strtod(strb,&endptr); 
                   9176:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9177:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9178:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9179:       fflush(ficlog);
                   9180:       return 1;
                   9181:     }
                   9182:     weight[i]=dval; 
                   9183:     strcpy(line,stra);
1.225     brouard  9184:     
1.223     brouard  9185:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9186:       cutv(stra, strb, line, ' '); 
                   9187:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9188:        lval=-1;
1.223     brouard  9189:       }else{
1.225     brouard  9190:        errno=0;
                   9191:        /* what_kind_of_number(strb); */
                   9192:        dval=strtod(strb,&endptr);
                   9193:        /* if(strb != endptr && *endptr == '\0') */
                   9194:        /*   dval=dlval; */
                   9195:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9196:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9197:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9198:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9199:          return 1;
                   9200:        }
                   9201:        coqvar[iv][i]=dval; 
1.226     brouard  9202:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9203:       }
                   9204:       strcpy(line,stra);
                   9205:     }/* end loop nqv */
1.136     brouard  9206:     
1.223     brouard  9207:     /* Covariate values */
1.136     brouard  9208:     for (j=ncovcol;j>=1;j--){
                   9209:       cutv(stra, strb,line,' '); 
1.223     brouard  9210:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9211:        lval=-1;
1.136     brouard  9212:       }else{
1.225     brouard  9213:        errno=0;
                   9214:        lval=strtol(strb,&endptr,10); 
                   9215:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9216:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9217:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9218:          return 1;
                   9219:        }
1.136     brouard  9220:       }
                   9221:       if(lval <-1 || lval >1){
1.225     brouard  9222:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9223:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9224:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9225:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9226:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9227:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9228:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9229:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9230:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9231:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9232:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9233:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9234:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9235:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9236:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9237:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9238:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9239:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9240:        return 1;
1.136     brouard  9241:       }
                   9242:       covar[j][i]=(double)(lval);
                   9243:       strcpy(line,stra);
                   9244:     }  
                   9245:     lstra=strlen(stra);
1.225     brouard  9246:     
1.136     brouard  9247:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9248:       stratrunc = &(stra[lstra-9]);
                   9249:       num[i]=atol(stratrunc);
                   9250:     }
                   9251:     else
                   9252:       num[i]=atol(stra);
                   9253:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9254:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9255:     
                   9256:     i=i+1;
                   9257:   } /* End loop reading  data */
1.225     brouard  9258:   
1.136     brouard  9259:   *imax=i-1; /* Number of individuals */
                   9260:   fclose(fic);
1.225     brouard  9261:   
1.136     brouard  9262:   return (0);
1.164     brouard  9263:   /* endread: */
1.225     brouard  9264:   printf("Exiting readdata: ");
                   9265:   fclose(fic);
                   9266:   return (1);
1.223     brouard  9267: }
1.126     brouard  9268: 
1.234     brouard  9269: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9270:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9271:   while (*p2 == ' ')
1.234     brouard  9272:     p2++; 
                   9273:   /* while ((*p1++ = *p2++) !=0) */
                   9274:   /*   ; */
                   9275:   /* do */
                   9276:   /*   while (*p2 == ' ') */
                   9277:   /*     p2++; */
                   9278:   /* while (*p1++ == *p2++); */
                   9279:   *stri=p2; 
1.145     brouard  9280: }
                   9281: 
1.235     brouard  9282: int decoderesult ( char resultline[], int nres)
1.230     brouard  9283: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9284: {
1.235     brouard  9285:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9286:   char resultsav[MAXLINE];
1.234     brouard  9287:   int resultmodel[MAXLINE];
                   9288:   int modelresult[MAXLINE];
1.230     brouard  9289:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9290: 
1.234     brouard  9291:   removefirstspace(&resultline);
1.233     brouard  9292:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9293: 
                   9294:   if (strstr(resultline,"v") !=0){
                   9295:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9296:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9297:     return 1;
                   9298:   }
                   9299:   trimbb(resultsav, resultline);
                   9300:   if (strlen(resultsav) >1){
                   9301:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9302:   }
1.253     brouard  9303:   if(j == 0){ /* Resultline but no = */
                   9304:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9305:     return (0);
                   9306:   }
                   9307:     
1.234     brouard  9308:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9309:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9310:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9311:   }
                   9312:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9313:     if(nbocc(resultsav,'=') >1){
                   9314:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9315:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9316:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9317:     }else
                   9318:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9319:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9320:     
1.230     brouard  9321:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9322:     Tvarsel[k]=atoi(strc);
                   9323:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9324:     /* cptcovsel++;     */
                   9325:     if (nbocc(stra,'=') >0)
                   9326:       strcpy(resultsav,stra); /* and analyzes it */
                   9327:   }
1.235     brouard  9328:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9329:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9330:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9331:       match=0;
1.236     brouard  9332:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9333:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9334:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9335:          match=1;
                   9336:          break;
                   9337:        }
                   9338:       }
                   9339:       if(match == 0){
                   9340:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9341:       }
                   9342:     }
                   9343:   }
1.235     brouard  9344:   /* Checking for missing or useless values in comparison of current model needs */
                   9345:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9346:     match=0;
1.235     brouard  9347:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9348:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9349:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9350:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9351:          ++match;
                   9352:        }
                   9353:       }
                   9354:     }
                   9355:     if(match == 0){
                   9356:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9357:     }else if(match > 1){
                   9358:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9359:     }
                   9360:   }
1.235     brouard  9361:       
1.234     brouard  9362:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9363:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9364:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9365:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9366:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9367:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9368:   /*    1 0 0 0 */
                   9369:   /*    2 1 0 0 */
                   9370:   /*    3 0 1 0 */ 
                   9371:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9372:   /*    5 0 0 1 */
                   9373:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9374:   /*    7 0 1 1 */
                   9375:   /*    8 1 1 1 */
1.237     brouard  9376:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9377:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9378:   /* V5*age V5 known which value for nres?  */
                   9379:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9380:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9381:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9382:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9383:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9384:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9385:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9386:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9387:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9388:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9389:       k4++;;
                   9390:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9391:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9392:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9393:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9394:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9395:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9396:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9397:       k4q++;;
                   9398:     }
                   9399:   }
1.234     brouard  9400:   
1.235     brouard  9401:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9402:   return (0);
                   9403: }
1.235     brouard  9404: 
1.230     brouard  9405: int decodemodel( char model[], int lastobs)
                   9406:  /**< This routine decodes the model and returns:
1.224     brouard  9407:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9408:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9409:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9410:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9411:        * - cptcovage number of covariates with age*products =2
                   9412:        * - cptcovs number of simple covariates
                   9413:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9414:        *     which is a new column after the 9 (ncovcol) variables. 
                   9415:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9416:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9417:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9418:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9419:        */
1.136     brouard  9420: {
1.238     brouard  9421:   int i, j, k, ks, v;
1.227     brouard  9422:   int  j1, k1, k2, k3, k4;
1.136     brouard  9423:   char modelsav[80];
1.145     brouard  9424:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9425:   char *strpt;
1.136     brouard  9426: 
1.145     brouard  9427:   /*removespace(model);*/
1.136     brouard  9428:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9429:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9430:     if (strstr(model,"AGE") !=0){
1.192     brouard  9431:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9432:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9433:       return 1;
                   9434:     }
1.141     brouard  9435:     if (strstr(model,"v") !=0){
                   9436:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9437:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9438:       return 1;
                   9439:     }
1.187     brouard  9440:     strcpy(modelsav,model); 
                   9441:     if ((strpt=strstr(model,"age*age")) !=0){
                   9442:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9443:       if(strpt != model){
1.234     brouard  9444:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9445:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9446:  corresponding column of parameters.\n",model);
1.234     brouard  9447:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9448:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9449:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9450:        return 1;
1.225     brouard  9451:       }
1.187     brouard  9452:       nagesqr=1;
                   9453:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9454:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9455:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9456:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9457:       else 
1.234     brouard  9458:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9459:     }else
                   9460:       nagesqr=0;
                   9461:     if (strlen(modelsav) >1){
                   9462:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9463:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9464:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9465:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9466:                     * cst, age and age*age 
                   9467:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9468:       /* including age products which are counted in cptcovage.
                   9469:        * but the covariates which are products must be treated 
                   9470:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9471:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9472:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9473:       
                   9474:       
1.187     brouard  9475:       /*   Design
                   9476:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9477:        *  <          ncovcol=8                >
                   9478:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9479:        *   k=  1    2      3       4     5       6      7        8
                   9480:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9481:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9482:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9483:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9484:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9485:        *  Tage[++cptcovage]=k
                   9486:        *       if products, new covar are created after ncovcol with k1
                   9487:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9488:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9489:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9490:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9491:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9492:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9493:        *  <          ncovcol=8                >
                   9494:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9495:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9496:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9497:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9498:        * p Tprod[1]@2={                         6, 5}
                   9499:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9500:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9501:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9502:        *How to reorganize?
                   9503:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9504:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9505:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9506:        * Struct []
                   9507:        */
1.225     brouard  9508:       
1.187     brouard  9509:       /* This loop fills the array Tvar from the string 'model'.*/
                   9510:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9511:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9512:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9513:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9514:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9515:       /*       k=1 Tvar[1]=2 (from V2) */
                   9516:       /*       k=5 Tvar[5] */
                   9517:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9518:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9519:       /*       } */
1.198     brouard  9520:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9521:       /*
                   9522:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9523:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9524:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9525:       }
1.187     brouard  9526:       cptcovage=0;
                   9527:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9528:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9529:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9530:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9531:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9532:        /*scanf("%d",i);*/
                   9533:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9534:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9535:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9536:            /* covar is not filled and then is empty */
                   9537:            cptcovprod--;
                   9538:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9539:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9540:            Typevar[k]=1;  /* 1 for age product */
                   9541:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9542:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9543:            /*printf("stre=%s ", stre);*/
                   9544:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9545:            cptcovprod--;
                   9546:            cutl(stre,strb,strc,'V');
                   9547:            Tvar[k]=atoi(stre);
                   9548:            Typevar[k]=1;  /* 1 for age product */
                   9549:            cptcovage++;
                   9550:            Tage[cptcovage]=k;
                   9551:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9552:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9553:            cptcovn++;
                   9554:            cptcovprodnoage++;k1++;
                   9555:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9556:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9557:                                                because this model-covariate is a construction we invent a new column
                   9558:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9559:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9560:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9561:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9562:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9563:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9564:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9565:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9566:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9567:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9568:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9569:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9570:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9571:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9572:            for (i=1; i<=lastobs;i++){
                   9573:              /* Computes the new covariate which is a product of
                   9574:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9575:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9576:            }
                   9577:          } /* End age is not in the model */
                   9578:        } /* End if model includes a product */
                   9579:        else { /* no more sum */
                   9580:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9581:          /*  scanf("%d",i);*/
                   9582:          cutl(strd,strc,strb,'V');
                   9583:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9584:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9585:          Tvar[k]=atoi(strd);
                   9586:          Typevar[k]=0;  /* 0 for simple covariates */
                   9587:        }
                   9588:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9589:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9590:                                  scanf("%d",i);*/
1.187     brouard  9591:       } /* end of loop + on total covariates */
                   9592:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9593:   } /* end if strlen(model == 0) */
1.136     brouard  9594:   
                   9595:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9596:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9597:   
1.136     brouard  9598:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9599:      printf("cptcovprod=%d ", cptcovprod);
                   9600:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9601:      scanf("%d ",i);*/
                   9602: 
                   9603: 
1.230     brouard  9604: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9605:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9606: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9607:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9608:    k =           1    2   3     4       5       6      7      8        9
                   9609:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9610:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9611:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9612:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9613:          Tmodelind[combination of covar]=k;
1.225     brouard  9614: */  
                   9615: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9616:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9617:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9618:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9619:   printf("Model=%s\n\
                   9620: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9621: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9622: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9623:   fprintf(ficlog,"Model=%s\n\
                   9624: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9625: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9626: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9627:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9628:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9629:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9630:       Fixed[k]= 0;
                   9631:       Dummy[k]= 0;
1.225     brouard  9632:       ncoveff++;
1.232     brouard  9633:       ncovf++;
1.234     brouard  9634:       nsd++;
                   9635:       modell[k].maintype= FTYPE;
                   9636:       TvarsD[nsd]=Tvar[k];
                   9637:       TvarsDind[nsd]=k;
                   9638:       TvarF[ncovf]=Tvar[k];
                   9639:       TvarFind[ncovf]=k;
                   9640:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9641:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9642:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9643:       Fixed[k]= 0;
                   9644:       Dummy[k]= 0;
                   9645:       ncoveff++;
                   9646:       ncovf++;
                   9647:       modell[k].maintype= FTYPE;
                   9648:       TvarF[ncovf]=Tvar[k];
                   9649:       TvarFind[ncovf]=k;
1.230     brouard  9650:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9651:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9652:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9653:       Fixed[k]= 0;
                   9654:       Dummy[k]= 1;
1.230     brouard  9655:       nqfveff++;
1.234     brouard  9656:       modell[k].maintype= FTYPE;
                   9657:       modell[k].subtype= FQ;
                   9658:       nsq++;
                   9659:       TvarsQ[nsq]=Tvar[k];
                   9660:       TvarsQind[nsq]=k;
1.232     brouard  9661:       ncovf++;
1.234     brouard  9662:       TvarF[ncovf]=Tvar[k];
                   9663:       TvarFind[ncovf]=k;
1.231     brouard  9664:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9665:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9666:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9667:       Fixed[k]= 1;
                   9668:       Dummy[k]= 0;
1.225     brouard  9669:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9670:       modell[k].maintype= VTYPE;
                   9671:       modell[k].subtype= VD;
                   9672:       nsd++;
                   9673:       TvarsD[nsd]=Tvar[k];
                   9674:       TvarsDind[nsd]=k;
                   9675:       ncovv++; /* Only simple time varying variables */
                   9676:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9677:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9678:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9679:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9680:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9681:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9682:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9683:       Fixed[k]= 1;
                   9684:       Dummy[k]= 1;
                   9685:       nqtveff++;
                   9686:       modell[k].maintype= VTYPE;
                   9687:       modell[k].subtype= VQ;
                   9688:       ncovv++; /* Only simple time varying variables */
                   9689:       nsq++;
                   9690:       TvarsQ[nsq]=Tvar[k];
                   9691:       TvarsQind[nsq]=k;
                   9692:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9693:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9694:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9695:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9696:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9697:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9698:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9699:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9700:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9701:       ncova++;
                   9702:       TvarA[ncova]=Tvar[k];
                   9703:       TvarAind[ncova]=k;
1.231     brouard  9704:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9705:        Fixed[k]= 2;
                   9706:        Dummy[k]= 2;
                   9707:        modell[k].maintype= ATYPE;
                   9708:        modell[k].subtype= APFD;
                   9709:        /* ncoveff++; */
1.227     brouard  9710:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9711:        Fixed[k]= 2;
                   9712:        Dummy[k]= 3;
                   9713:        modell[k].maintype= ATYPE;
                   9714:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9715:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9716:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9717:        Fixed[k]= 3;
                   9718:        Dummy[k]= 2;
                   9719:        modell[k].maintype= ATYPE;
                   9720:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9721:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9722:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9723:        Fixed[k]= 3;
                   9724:        Dummy[k]= 3;
                   9725:        modell[k].maintype= ATYPE;
                   9726:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9727:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9728:       }
                   9729:     }else if (Typevar[k] == 2) {  /* product without age */
                   9730:       k1=Tposprod[k];
                   9731:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9732:        if(Tvard[k1][2] <=ncovcol){
                   9733:          Fixed[k]= 1;
                   9734:          Dummy[k]= 0;
                   9735:          modell[k].maintype= FTYPE;
                   9736:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9737:          ncovf++; /* Fixed variables without age */
                   9738:          TvarF[ncovf]=Tvar[k];
                   9739:          TvarFind[ncovf]=k;
                   9740:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9741:          Fixed[k]= 0;  /* or 2 ?*/
                   9742:          Dummy[k]= 1;
                   9743:          modell[k].maintype= FTYPE;
                   9744:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9745:          ncovf++; /* Varying variables without age */
                   9746:          TvarF[ncovf]=Tvar[k];
                   9747:          TvarFind[ncovf]=k;
                   9748:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9749:          Fixed[k]= 1;
                   9750:          Dummy[k]= 0;
                   9751:          modell[k].maintype= VTYPE;
                   9752:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9753:          ncovv++; /* Varying variables without age */
                   9754:          TvarV[ncovv]=Tvar[k];
                   9755:          TvarVind[ncovv]=k;
                   9756:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9757:          Fixed[k]= 1;
                   9758:          Dummy[k]= 1;
                   9759:          modell[k].maintype= VTYPE;
                   9760:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9761:          ncovv++; /* Varying variables without age */
                   9762:          TvarV[ncovv]=Tvar[k];
                   9763:          TvarVind[ncovv]=k;
                   9764:        }
1.227     brouard  9765:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9766:        if(Tvard[k1][2] <=ncovcol){
                   9767:          Fixed[k]= 0;  /* or 2 ?*/
                   9768:          Dummy[k]= 1;
                   9769:          modell[k].maintype= FTYPE;
                   9770:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9771:          ncovf++; /* Fixed variables without age */
                   9772:          TvarF[ncovf]=Tvar[k];
                   9773:          TvarFind[ncovf]=k;
                   9774:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9775:          Fixed[k]= 1;
                   9776:          Dummy[k]= 1;
                   9777:          modell[k].maintype= VTYPE;
                   9778:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9779:          ncovv++; /* Varying variables without age */
                   9780:          TvarV[ncovv]=Tvar[k];
                   9781:          TvarVind[ncovv]=k;
                   9782:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9783:          Fixed[k]= 1;
                   9784:          Dummy[k]= 1;
                   9785:          modell[k].maintype= VTYPE;
                   9786:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9787:          ncovv++; /* Varying variables without age */
                   9788:          TvarV[ncovv]=Tvar[k];
                   9789:          TvarVind[ncovv]=k;
                   9790:          ncovv++; /* Varying variables without age */
                   9791:          TvarV[ncovv]=Tvar[k];
                   9792:          TvarVind[ncovv]=k;
                   9793:        }
1.227     brouard  9794:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9795:        if(Tvard[k1][2] <=ncovcol){
                   9796:          Fixed[k]= 1;
                   9797:          Dummy[k]= 1;
                   9798:          modell[k].maintype= VTYPE;
                   9799:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9800:          ncovv++; /* Varying variables without age */
                   9801:          TvarV[ncovv]=Tvar[k];
                   9802:          TvarVind[ncovv]=k;
                   9803:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9804:          Fixed[k]= 1;
                   9805:          Dummy[k]= 1;
                   9806:          modell[k].maintype= VTYPE;
                   9807:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9808:          ncovv++; /* Varying variables without age */
                   9809:          TvarV[ncovv]=Tvar[k];
                   9810:          TvarVind[ncovv]=k;
                   9811:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9812:          Fixed[k]= 1;
                   9813:          Dummy[k]= 0;
                   9814:          modell[k].maintype= VTYPE;
                   9815:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9816:          ncovv++; /* Varying variables without age */
                   9817:          TvarV[ncovv]=Tvar[k];
                   9818:          TvarVind[ncovv]=k;
                   9819:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9820:          Fixed[k]= 1;
                   9821:          Dummy[k]= 1;
                   9822:          modell[k].maintype= VTYPE;
                   9823:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9824:          ncovv++; /* Varying variables without age */
                   9825:          TvarV[ncovv]=Tvar[k];
                   9826:          TvarVind[ncovv]=k;
                   9827:        }
1.227     brouard  9828:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9829:        if(Tvard[k1][2] <=ncovcol){
                   9830:          Fixed[k]= 1;
                   9831:          Dummy[k]= 1;
                   9832:          modell[k].maintype= VTYPE;
                   9833:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9834:          ncovv++; /* Varying variables without age */
                   9835:          TvarV[ncovv]=Tvar[k];
                   9836:          TvarVind[ncovv]=k;
                   9837:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9838:          Fixed[k]= 1;
                   9839:          Dummy[k]= 1;
                   9840:          modell[k].maintype= VTYPE;
                   9841:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9842:          ncovv++; /* Varying variables without age */
                   9843:          TvarV[ncovv]=Tvar[k];
                   9844:          TvarVind[ncovv]=k;
                   9845:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9846:          Fixed[k]= 1;
                   9847:          Dummy[k]= 1;
                   9848:          modell[k].maintype= VTYPE;
                   9849:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9850:          ncovv++; /* Varying variables without age */
                   9851:          TvarV[ncovv]=Tvar[k];
                   9852:          TvarVind[ncovv]=k;
                   9853:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9854:          Fixed[k]= 1;
                   9855:          Dummy[k]= 1;
                   9856:          modell[k].maintype= VTYPE;
                   9857:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9858:          ncovv++; /* Varying variables without age */
                   9859:          TvarV[ncovv]=Tvar[k];
                   9860:          TvarVind[ncovv]=k;
                   9861:        }
1.227     brouard  9862:       }else{
1.240     brouard  9863:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9864:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9865:       } /*end k1*/
1.225     brouard  9866:     }else{
1.226     brouard  9867:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9868:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9869:     }
1.227     brouard  9870:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9871:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9872:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9873:   }
                   9874:   /* Searching for doublons in the model */
                   9875:   for(k1=1; k1<= cptcovt;k1++){
                   9876:     for(k2=1; k2 <k1;k2++){
                   9877:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9878:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9879:          if(Tvar[k1]==Tvar[k2]){
                   9880:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9881:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9882:            return(1);
                   9883:          }
                   9884:        }else if (Typevar[k1] ==2){
                   9885:          k3=Tposprod[k1];
                   9886:          k4=Tposprod[k2];
                   9887:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9888:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9889:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9890:            return(1);
                   9891:          }
                   9892:        }
1.227     brouard  9893:       }
                   9894:     }
1.225     brouard  9895:   }
                   9896:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9897:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9898:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9899:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9900:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9901:   /*endread:*/
1.225     brouard  9902:   printf("Exiting decodemodel: ");
                   9903:   return (1);
1.136     brouard  9904: }
                   9905: 
1.169     brouard  9906: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9907: {/* Check ages at death */
1.136     brouard  9908:   int i, m;
1.218     brouard  9909:   int firstone=0;
                   9910:   
1.136     brouard  9911:   for (i=1; i<=imx; i++) {
                   9912:     for(m=2; (m<= maxwav); m++) {
                   9913:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9914:        anint[m][i]=9999;
1.216     brouard  9915:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9916:          s[m][i]=-1;
1.136     brouard  9917:       }
                   9918:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9919:        *nberr = *nberr + 1;
1.218     brouard  9920:        if(firstone == 0){
                   9921:          firstone=1;
1.260     brouard  9922:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9923:        }
1.262     brouard  9924:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9925:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9926:       }
                   9927:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9928:        (*nberr)++;
1.259     brouard  9929:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9930:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9931:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9932:       }
                   9933:     }
                   9934:   }
                   9935: 
                   9936:   for (i=1; i<=imx; i++)  {
                   9937:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9938:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9939:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9940:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9941:          if(agedc[i]>0){
                   9942:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9943:              agev[m][i]=agedc[i];
1.214     brouard  9944:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9945:            }else {
1.136     brouard  9946:              if ((int)andc[i]!=9999){
                   9947:                nbwarn++;
                   9948:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9949:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9950:                agev[m][i]=-1;
                   9951:              }
                   9952:            }
1.169     brouard  9953:          } /* agedc > 0 */
1.214     brouard  9954:        } /* end if */
1.136     brouard  9955:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9956:                                 years but with the precision of a month */
                   9957:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9958:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9959:            agev[m][i]=1;
                   9960:          else if(agev[m][i] < *agemin){ 
                   9961:            *agemin=agev[m][i];
                   9962:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9963:          }
                   9964:          else if(agev[m][i] >*agemax){
                   9965:            *agemax=agev[m][i];
1.156     brouard  9966:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9967:          }
                   9968:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9969:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9970:        } /* en if 9*/
1.136     brouard  9971:        else { /* =9 */
1.214     brouard  9972:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9973:          agev[m][i]=1;
                   9974:          s[m][i]=-1;
                   9975:        }
                   9976:       }
1.214     brouard  9977:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9978:        agev[m][i]=1;
1.214     brouard  9979:       else{
                   9980:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9981:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9982:        agev[m][i]=0;
                   9983:       }
                   9984:     } /* End for lastpass */
                   9985:   }
1.136     brouard  9986:     
                   9987:   for (i=1; i<=imx; i++)  {
                   9988:     for(m=firstpass; (m<=lastpass); m++){
                   9989:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9990:        (*nberr)++;
1.136     brouard  9991:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9992:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9993:        return 1;
                   9994:       }
                   9995:     }
                   9996:   }
                   9997: 
                   9998:   /*for (i=1; i<=imx; i++){
                   9999:   for (m=firstpass; (m<lastpass); m++){
                   10000:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10001: }
                   10002: 
                   10003: }*/
                   10004: 
                   10005: 
1.139     brouard  10006:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10007:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10008: 
                   10009:   return (0);
1.164     brouard  10010:  /* endread:*/
1.136     brouard  10011:     printf("Exiting calandcheckages: ");
                   10012:     return (1);
                   10013: }
                   10014: 
1.172     brouard  10015: #if defined(_MSC_VER)
                   10016: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10017: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10018: //#include "stdafx.h"
                   10019: //#include <stdio.h>
                   10020: //#include <tchar.h>
                   10021: //#include <windows.h>
                   10022: //#include <iostream>
                   10023: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10024: 
                   10025: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10026: 
                   10027: BOOL IsWow64()
                   10028: {
                   10029:        BOOL bIsWow64 = FALSE;
                   10030: 
                   10031:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10032:        //  (HANDLE, PBOOL);
                   10033: 
                   10034:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10035: 
                   10036:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10037:        const char funcName[] = "IsWow64Process";
                   10038:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10039:                GetProcAddress(module, funcName);
                   10040: 
                   10041:        if (NULL != fnIsWow64Process)
                   10042:        {
                   10043:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10044:                        &bIsWow64))
                   10045:                        //throw std::exception("Unknown error");
                   10046:                        printf("Unknown error\n");
                   10047:        }
                   10048:        return bIsWow64 != FALSE;
                   10049: }
                   10050: #endif
1.177     brouard  10051: 
1.191     brouard  10052: void syscompilerinfo(int logged)
1.167     brouard  10053:  {
                   10054:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10055:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10056:    /* /GS /W3 /Gy
                   10057:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10058:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10059:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10060:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10061:    */ 
                   10062:    /* 64 bits */
1.185     brouard  10063:    /*
                   10064:      /GS /W3 /Gy
                   10065:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10066:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10067:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10068:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10069:    /* Optimization are useless and O3 is slower than O2 */
                   10070:    /*
                   10071:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10072:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10073:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10074:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10075:    */
1.186     brouard  10076:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10077:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10078:       /PDB:"visual studio
                   10079:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10080:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10081:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10082:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10083:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10084:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10085:       uiAccess='false'"
                   10086:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10087:       /NOLOGO /TLBID:1
                   10088:    */
1.177     brouard  10089: #if defined __INTEL_COMPILER
1.178     brouard  10090: #if defined(__GNUC__)
                   10091:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10092: #endif
1.177     brouard  10093: #elif defined(__GNUC__) 
1.179     brouard  10094: #ifndef  __APPLE__
1.174     brouard  10095: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10096: #endif
1.177     brouard  10097:    struct utsname sysInfo;
1.178     brouard  10098:    int cross = CROSS;
                   10099:    if (cross){
                   10100:           printf("Cross-");
1.191     brouard  10101:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10102:    }
1.174     brouard  10103: #endif
                   10104: 
1.171     brouard  10105: #include <stdint.h>
1.178     brouard  10106: 
1.191     brouard  10107:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10108: #if defined(__clang__)
1.191     brouard  10109:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10110: #endif
                   10111: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10112:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10113: #endif
                   10114: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10115:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10116: #endif
                   10117: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10118:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10119: #endif
                   10120: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10121:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10122: #endif
                   10123: #if defined(_MSC_VER)
1.191     brouard  10124:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10125: #endif
                   10126: #if defined(__PGI)
1.191     brouard  10127:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10128: #endif
                   10129: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10130:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10131: #endif
1.191     brouard  10132:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10133:    
1.167     brouard  10134: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10135: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10136:     // Windows (x64 and x86)
1.191     brouard  10137:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10138: #elif __unix__ // all unices, not all compilers
                   10139:     // Unix
1.191     brouard  10140:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10141: #elif __linux__
                   10142:     // linux
1.191     brouard  10143:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10144: #elif __APPLE__
1.174     brouard  10145:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10146:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10147: #endif
                   10148: 
                   10149: /*  __MINGW32__          */
                   10150: /*  __CYGWIN__  */
                   10151: /* __MINGW64__  */
                   10152: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10153: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10154: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10155: /* _WIN64  // Defined for applications for Win64. */
                   10156: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10157: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10158: 
1.167     brouard  10159: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10160:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10161: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10162:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10163: #else
1.191     brouard  10164:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10165: #endif
                   10166: 
1.169     brouard  10167: #if defined(__GNUC__)
                   10168: # if defined(__GNUC_PATCHLEVEL__)
                   10169: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10170:                             + __GNUC_MINOR__ * 100 \
                   10171:                             + __GNUC_PATCHLEVEL__)
                   10172: # else
                   10173: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10174:                             + __GNUC_MINOR__ * 100)
                   10175: # endif
1.174     brouard  10176:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10177:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10178: 
                   10179:    if (uname(&sysInfo) != -1) {
                   10180:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10181:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10182:    }
                   10183:    else
                   10184:       perror("uname() error");
1.179     brouard  10185:    //#ifndef __INTEL_COMPILER 
                   10186: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10187:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10188:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10189: #endif
1.169     brouard  10190: #endif
1.172     brouard  10191: 
                   10192:    //   void main()
                   10193:    //   {
1.169     brouard  10194: #if defined(_MSC_VER)
1.174     brouard  10195:    if (IsWow64()){
1.191     brouard  10196:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10197:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10198:    }
                   10199:    else{
1.191     brouard  10200:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10201:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10202:    }
1.172     brouard  10203:    //     printf("\nPress Enter to continue...");
                   10204:    //     getchar();
                   10205:    //   }
                   10206: 
1.169     brouard  10207: #endif
                   10208:    
1.167     brouard  10209: 
1.219     brouard  10210: }
1.136     brouard  10211: 
1.219     brouard  10212: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10213:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10214:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10215:   /* double ftolpl = 1.e-10; */
1.180     brouard  10216:   double age, agebase, agelim;
1.203     brouard  10217:   double tot;
1.180     brouard  10218: 
1.202     brouard  10219:   strcpy(filerespl,"PL_");
                   10220:   strcat(filerespl,fileresu);
                   10221:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10222:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10223:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10224:   }
1.227     brouard  10225:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10226:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10227:   pstamp(ficrespl);
1.203     brouard  10228:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10229:   fprintf(ficrespl,"#Age ");
                   10230:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10231:   fprintf(ficrespl,"\n");
1.180     brouard  10232:   
1.219     brouard  10233:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10234: 
1.219     brouard  10235:   agebase=ageminpar;
                   10236:   agelim=agemaxpar;
1.180     brouard  10237: 
1.227     brouard  10238:   /* i1=pow(2,ncoveff); */
1.234     brouard  10239:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10240:   if (cptcovn < 1){i1=1;}
1.180     brouard  10241: 
1.238     brouard  10242:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10243:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10244:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10245:        continue;
1.235     brouard  10246: 
1.238     brouard  10247:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10248:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10249:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10250:       /* k=k+1; */
                   10251:       /* to clean */
                   10252:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10253:       fprintf(ficrespl,"#******");
                   10254:       printf("#******");
                   10255:       fprintf(ficlog,"#******");
                   10256:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10257:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10258:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10259:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10260:       }
                   10261:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10262:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10263:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10264:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10265:       }
                   10266:       fprintf(ficrespl,"******\n");
                   10267:       printf("******\n");
                   10268:       fprintf(ficlog,"******\n");
                   10269:       if(invalidvarcomb[k]){
                   10270:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10271:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10272:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10273:        continue;
                   10274:       }
1.219     brouard  10275: 
1.238     brouard  10276:       fprintf(ficrespl,"#Age ");
                   10277:       for(j=1;j<=cptcoveff;j++) {
                   10278:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10279:       }
                   10280:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10281:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10282:     
1.238     brouard  10283:       for (age=agebase; age<=agelim; age++){
                   10284:        /* for (age=agebase; age<=agebase; age++){ */
                   10285:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10286:        fprintf(ficrespl,"%.0f ",age );
                   10287:        for(j=1;j<=cptcoveff;j++)
                   10288:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10289:        tot=0.;
                   10290:        for(i=1; i<=nlstate;i++){
                   10291:          tot +=  prlim[i][i];
                   10292:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10293:        }
                   10294:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10295:       } /* Age */
                   10296:       /* was end of cptcod */
                   10297:     } /* cptcov */
                   10298:   } /* nres */
1.219     brouard  10299:   return 0;
1.180     brouard  10300: }
                   10301: 
1.218     brouard  10302: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10303:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10304:        
                   10305:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10306:    * at any age between ageminpar and agemaxpar
                   10307:         */
1.235     brouard  10308:   int i, j, k, i1, nres=0 ;
1.217     brouard  10309:   /* double ftolpl = 1.e-10; */
                   10310:   double age, agebase, agelim;
                   10311:   double tot;
1.218     brouard  10312:   /* double ***mobaverage; */
                   10313:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10314: 
                   10315:   strcpy(fileresplb,"PLB_");
                   10316:   strcat(fileresplb,fileresu);
                   10317:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10318:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10319:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10320:   }
                   10321:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10322:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10323:   pstamp(ficresplb);
                   10324:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10325:   fprintf(ficresplb,"#Age ");
                   10326:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10327:   fprintf(ficresplb,"\n");
                   10328:   
1.218     brouard  10329:   
                   10330:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10331:   
                   10332:   agebase=ageminpar;
                   10333:   agelim=agemaxpar;
                   10334:   
                   10335:   
1.227     brouard  10336:   i1=pow(2,cptcoveff);
1.218     brouard  10337:   if (cptcovn < 1){i1=1;}
1.227     brouard  10338:   
1.238     brouard  10339:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10340:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10341:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10342:        continue;
                   10343:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10344:       fprintf(ficresplb,"#******");
                   10345:       printf("#******");
                   10346:       fprintf(ficlog,"#******");
                   10347:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10348:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10349:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10350:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10351:       }
                   10352:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10353:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10354:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10355:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10356:       }
                   10357:       fprintf(ficresplb,"******\n");
                   10358:       printf("******\n");
                   10359:       fprintf(ficlog,"******\n");
                   10360:       if(invalidvarcomb[k]){
                   10361:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10362:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10363:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10364:        continue;
                   10365:       }
1.218     brouard  10366:     
1.238     brouard  10367:       fprintf(ficresplb,"#Age ");
                   10368:       for(j=1;j<=cptcoveff;j++) {
                   10369:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10370:       }
                   10371:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10372:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10373:     
                   10374:     
1.238     brouard  10375:       for (age=agebase; age<=agelim; age++){
                   10376:        /* for (age=agebase; age<=agebase; age++){ */
                   10377:        if(mobilavproj > 0){
                   10378:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10379:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10380:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10381:        }else if (mobilavproj == 0){
                   10382:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10383:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10384:          exit(1);
                   10385:        }else{
                   10386:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10387:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10388:          /* printf("TOTOT\n"); */
                   10389:           /* exit(1); */
1.238     brouard  10390:        }
                   10391:        fprintf(ficresplb,"%.0f ",age );
                   10392:        for(j=1;j<=cptcoveff;j++)
                   10393:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10394:        tot=0.;
                   10395:        for(i=1; i<=nlstate;i++){
                   10396:          tot +=  bprlim[i][i];
                   10397:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10398:        }
                   10399:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10400:       } /* Age */
                   10401:       /* was end of cptcod */
1.255     brouard  10402:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10403:     } /* end of any combination */
                   10404:   } /* end of nres */  
1.218     brouard  10405:   /* hBijx(p, bage, fage); */
                   10406:   /* fclose(ficrespijb); */
                   10407:   
                   10408:   return 0;
1.217     brouard  10409: }
1.218     brouard  10410:  
1.180     brouard  10411: int hPijx(double *p, int bage, int fage){
                   10412:     /*------------- h Pij x at various ages ------------*/
                   10413: 
                   10414:   int stepsize;
                   10415:   int agelim;
                   10416:   int hstepm;
                   10417:   int nhstepm;
1.235     brouard  10418:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10419: 
                   10420:   double agedeb;
                   10421:   double ***p3mat;
                   10422: 
1.201     brouard  10423:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10424:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10425:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10426:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10427:     }
                   10428:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10429:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10430:   
                   10431:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10432:     /*if (stepm<=24) stepsize=2;*/
                   10433: 
                   10434:     agelim=AGESUP;
                   10435:     hstepm=stepsize*YEARM; /* Every year of age */
                   10436:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10437:                
1.180     brouard  10438:     /* hstepm=1;   aff par mois*/
                   10439:     pstamp(ficrespij);
                   10440:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10441:     i1= pow(2,cptcoveff);
1.218     brouard  10442:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10443:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10444:                /*      k=k+1;  */
1.235     brouard  10445:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10446:     for(k=1; k<=i1;k++){
1.253     brouard  10447:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10448:        continue;
1.183     brouard  10449:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10450:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10451:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10452:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10453:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10454:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10455:       }
1.183     brouard  10456:       fprintf(ficrespij,"******\n");
                   10457:       
                   10458:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10459:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10460:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10461:        
                   10462:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10463:        
1.183     brouard  10464:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10465:        oldm=oldms;savm=savms;
1.235     brouard  10466:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10467:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10468:        for(i=1; i<=nlstate;i++)
                   10469:          for(j=1; j<=nlstate+ndeath;j++)
                   10470:            fprintf(ficrespij," %1d-%1d",i,j);
                   10471:        fprintf(ficrespij,"\n");
                   10472:        for (h=0; h<=nhstepm; h++){
                   10473:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10474:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10475:          for(i=1; i<=nlstate;i++)
                   10476:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10477:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10478:          fprintf(ficrespij,"\n");
                   10479:        }
1.183     brouard  10480:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10481:        fprintf(ficrespij,"\n");
                   10482:       }
1.180     brouard  10483:       /*}*/
                   10484:     }
1.218     brouard  10485:     return 0;
1.180     brouard  10486: }
1.218     brouard  10487:  
                   10488:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10489:     /*------------- h Bij x at various ages ------------*/
                   10490: 
                   10491:   int stepsize;
1.218     brouard  10492:   /* int agelim; */
                   10493:        int ageminl;
1.217     brouard  10494:   int hstepm;
                   10495:   int nhstepm;
1.238     brouard  10496:   int h, i, i1, j, k, nres;
1.218     brouard  10497:        
1.217     brouard  10498:   double agedeb;
                   10499:   double ***p3mat;
1.218     brouard  10500:        
                   10501:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10502:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10503:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10504:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10505:   }
                   10506:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10507:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10508:   
                   10509:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10510:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10511:   
1.218     brouard  10512:   /* agelim=AGESUP; */
                   10513:   ageminl=30;
                   10514:   hstepm=stepsize*YEARM; /* Every year of age */
                   10515:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10516:   
                   10517:   /* hstepm=1;   aff par mois*/
                   10518:   pstamp(ficrespijb);
1.255     brouard  10519:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10520:   i1= pow(2,cptcoveff);
1.218     brouard  10521:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10522:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10523:   /*   k=k+1;  */
1.238     brouard  10524:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10525:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10526:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10527:        continue;
                   10528:       fprintf(ficrespijb,"\n#****** ");
                   10529:       for(j=1;j<=cptcoveff;j++)
                   10530:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10531:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10532:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10533:       }
                   10534:       fprintf(ficrespijb,"******\n");
1.264     brouard  10535:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10536:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10537:        continue;
                   10538:       }
                   10539:       
                   10540:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10541:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10542:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10543:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10544:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10545:        
                   10546:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10547:        
1.266     brouard  10548:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10549:        /* and memory limitations if stepm is small */
                   10550: 
1.238     brouard  10551:        /* oldm=oldms;savm=savms; */
                   10552:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10553:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10554:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10555:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10556:        for(i=1; i<=nlstate;i++)
                   10557:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10558:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10559:        fprintf(ficrespijb,"\n");
1.238     brouard  10560:        for (h=0; h<=nhstepm; h++){
                   10561:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10562:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10563:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10564:          for(i=1; i<=nlstate;i++)
                   10565:            for(j=1; j<=nlstate+ndeath;j++)
                   10566:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10567:          fprintf(ficrespijb,"\n");
                   10568:        }
                   10569:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10570:        fprintf(ficrespijb,"\n");
                   10571:       } /* end age deb */
                   10572:     } /* end combination */
                   10573:   } /* end nres */
1.218     brouard  10574:   return 0;
                   10575:  } /*  hBijx */
1.217     brouard  10576: 
1.180     brouard  10577: 
1.136     brouard  10578: /***********************************************/
                   10579: /**************** Main Program *****************/
                   10580: /***********************************************/
                   10581: 
                   10582: int main(int argc, char *argv[])
                   10583: {
                   10584: #ifdef GSL
                   10585:   const gsl_multimin_fminimizer_type *T;
                   10586:   size_t iteri = 0, it;
                   10587:   int rval = GSL_CONTINUE;
                   10588:   int status = GSL_SUCCESS;
                   10589:   double ssval;
                   10590: #endif
                   10591:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10592:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10593:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10594:   int jj, ll, li, lj, lk;
1.136     brouard  10595:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10596:   int num_filled;
1.136     brouard  10597:   int itimes;
                   10598:   int NDIM=2;
                   10599:   int vpopbased=0;
1.235     brouard  10600:   int nres=0;
1.258     brouard  10601:   int endishere=0;
1.136     brouard  10602: 
1.274   ! brouard  10603:   int ncurrv=0; /* Temporary variable */
        !          10604:   
1.164     brouard  10605:   char ca[32], cb[32];
1.136     brouard  10606:   /*  FILE *fichtm; *//* Html File */
                   10607:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10608:   struct stat info;
1.191     brouard  10609:   double agedeb=0.;
1.194     brouard  10610: 
                   10611:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10612:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10613: 
1.165     brouard  10614:   double fret;
1.191     brouard  10615:   double dum=0.; /* Dummy variable */
1.136     brouard  10616:   double ***p3mat;
1.218     brouard  10617:   /* double ***mobaverage; */
1.164     brouard  10618: 
                   10619:   char line[MAXLINE];
1.197     brouard  10620:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10621: 
1.234     brouard  10622:   char  modeltemp[MAXLINE];
1.230     brouard  10623:   char resultline[MAXLINE];
                   10624:   
1.136     brouard  10625:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10626:   char *tok, *val; /* pathtot */
1.136     brouard  10627:   int firstobs=1, lastobs=10;
1.195     brouard  10628:   int c,  h , cpt, c2;
1.191     brouard  10629:   int jl=0;
                   10630:   int i1, j1, jk, stepsize=0;
1.194     brouard  10631:   int count=0;
                   10632: 
1.164     brouard  10633:   int *tab; 
1.136     brouard  10634:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10635:   int backcast=0;
1.136     brouard  10636:   int mobilav=0,popforecast=0;
1.191     brouard  10637:   int hstepm=0, nhstepm=0;
1.136     brouard  10638:   int agemortsup;
                   10639:   float  sumlpop=0.;
                   10640:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10641:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10642: 
1.191     brouard  10643:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10644:   double ftolpl=FTOL;
                   10645:   double **prlim;
1.217     brouard  10646:   double **bprlim;
1.136     brouard  10647:   double ***param; /* Matrix of parameters */
1.251     brouard  10648:   double ***paramstart; /* Matrix of starting parameter values */
                   10649:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10650:   double **matcov; /* Matrix of covariance */
1.203     brouard  10651:   double **hess; /* Hessian matrix */
1.136     brouard  10652:   double ***delti3; /* Scale */
                   10653:   double *delti; /* Scale */
                   10654:   double ***eij, ***vareij;
                   10655:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10656: 
1.136     brouard  10657:   double *epj, vepp;
1.164     brouard  10658: 
1.273     brouard  10659:   double dateprev1, dateprev2;
                   10660:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10661:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10662: 
1.136     brouard  10663:   double **ximort;
1.145     brouard  10664:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10665:   int *dcwave;
                   10666: 
1.164     brouard  10667:   char z[1]="c";
1.136     brouard  10668: 
                   10669:   /*char  *strt;*/
                   10670:   char strtend[80];
1.126     brouard  10671: 
1.164     brouard  10672: 
1.126     brouard  10673: /*   setlocale (LC_ALL, ""); */
                   10674: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10675: /*   textdomain (PACKAGE); */
                   10676: /*   setlocale (LC_CTYPE, ""); */
                   10677: /*   setlocale (LC_MESSAGES, ""); */
                   10678: 
                   10679:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10680:   rstart_time = time(NULL);  
                   10681:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10682:   start_time = *localtime(&rstart_time);
1.126     brouard  10683:   curr_time=start_time;
1.157     brouard  10684:   /*tml = *localtime(&start_time.tm_sec);*/
                   10685:   /* strcpy(strstart,asctime(&tml)); */
                   10686:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10687: 
                   10688: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10689: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10690: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10691: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10692: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10693: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10694: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10695: /*   strt=asctime(&tmg); */
                   10696: /*   printf("Time(after) =%s",strstart);  */
                   10697: /*  (void) time (&time_value);
                   10698: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10699: *  tm = *localtime(&time_value);
                   10700: *  strstart=asctime(&tm);
                   10701: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10702: */
                   10703: 
                   10704:   nberr=0; /* Number of errors and warnings */
                   10705:   nbwarn=0;
1.184     brouard  10706: #ifdef WIN32
                   10707:   _getcwd(pathcd, size);
                   10708: #else
1.126     brouard  10709:   getcwd(pathcd, size);
1.184     brouard  10710: #endif
1.191     brouard  10711:   syscompilerinfo(0);
1.196     brouard  10712:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10713:   if(argc <=1){
                   10714:     printf("\nEnter the parameter file name: ");
1.205     brouard  10715:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10716:       printf("ERROR Empty parameter file name\n");
                   10717:       goto end;
                   10718:     }
1.126     brouard  10719:     i=strlen(pathr);
                   10720:     if(pathr[i-1]=='\n')
                   10721:       pathr[i-1]='\0';
1.156     brouard  10722:     i=strlen(pathr);
1.205     brouard  10723:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10724:       pathr[i-1]='\0';
1.205     brouard  10725:     }
                   10726:     i=strlen(pathr);
                   10727:     if( i==0 ){
                   10728:       printf("ERROR Empty parameter file name\n");
                   10729:       goto end;
                   10730:     }
                   10731:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10732:       printf("Pathr |%s|\n",pathr);
                   10733:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10734:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10735:       strcpy (pathtot, val);
                   10736:       if(pathr[0] == '\0') break; /* Dirty */
                   10737:     }
                   10738:   }
                   10739:   else{
                   10740:     strcpy(pathtot,argv[1]);
                   10741:   }
                   10742:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10743:   /*cygwin_split_path(pathtot,path,optionfile);
                   10744:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10745:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10746: 
                   10747:   /* Split argv[0], imach program to get pathimach */
                   10748:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10749:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10750:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10751:  /*   strcpy(pathimach,argv[0]); */
                   10752:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10753:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10754:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10755: #ifdef WIN32
                   10756:   _chdir(path); /* Can be a relative path */
                   10757:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10758: #else
1.126     brouard  10759:   chdir(path); /* Can be a relative path */
1.184     brouard  10760:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10761: #endif
                   10762:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10763:   strcpy(command,"mkdir ");
                   10764:   strcat(command,optionfilefiname);
                   10765:   if((outcmd=system(command)) != 0){
1.169     brouard  10766:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10767:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10768:     /* fclose(ficlog); */
                   10769: /*     exit(1); */
                   10770:   }
                   10771: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10772: /*     perror("mkdir"); */
                   10773: /*   } */
                   10774: 
                   10775:   /*-------- arguments in the command line --------*/
                   10776: 
1.186     brouard  10777:   /* Main Log file */
1.126     brouard  10778:   strcat(filelog, optionfilefiname);
                   10779:   strcat(filelog,".log");    /* */
                   10780:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10781:     printf("Problem with logfile %s\n",filelog);
                   10782:     goto end;
                   10783:   }
                   10784:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10785:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10786:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10787:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10788:  path=%s \n\
                   10789:  optionfile=%s\n\
                   10790:  optionfilext=%s\n\
1.156     brouard  10791:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10792: 
1.197     brouard  10793:   syscompilerinfo(1);
1.167     brouard  10794: 
1.126     brouard  10795:   printf("Local time (at start):%s",strstart);
                   10796:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10797:   fflush(ficlog);
                   10798: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10799: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10800: 
                   10801:   /* */
                   10802:   strcpy(fileres,"r");
                   10803:   strcat(fileres, optionfilefiname);
1.201     brouard  10804:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10805:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10806:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10807: 
1.186     brouard  10808:   /* Main ---------arguments file --------*/
1.126     brouard  10809: 
                   10810:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10811:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10812:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10813:     fflush(ficlog);
1.149     brouard  10814:     /* goto end; */
                   10815:     exit(70); 
1.126     brouard  10816:   }
                   10817: 
                   10818: 
                   10819: 
                   10820:   strcpy(filereso,"o");
1.201     brouard  10821:   strcat(filereso,fileresu);
1.126     brouard  10822:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10823:     printf("Problem with Output resultfile: %s\n", filereso);
                   10824:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10825:     fflush(ficlog);
                   10826:     goto end;
                   10827:   }
                   10828: 
                   10829:   /* Reads comments: lines beginning with '#' */
                   10830:   numlinepar=0;
1.197     brouard  10831: 
                   10832:     /* First parameter line */
                   10833:   while(fgets(line, MAXLINE, ficpar)) {
                   10834:     /* If line starts with a # it is a comment */
                   10835:     if (line[0] == '#') {
                   10836:       numlinepar++;
                   10837:       fputs(line,stdout);
                   10838:       fputs(line,ficparo);
                   10839:       fputs(line,ficlog);
                   10840:       continue;
                   10841:     }else
                   10842:       break;
                   10843:   }
                   10844:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10845:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10846:     if (num_filled != 5) {
                   10847:       printf("Should be 5 parameters\n");
                   10848:     }
1.126     brouard  10849:     numlinepar++;
1.197     brouard  10850:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10851:   }
                   10852:   /* Second parameter line */
                   10853:   while(fgets(line, MAXLINE, ficpar)) {
                   10854:     /* If line starts with a # it is a comment */
                   10855:     if (line[0] == '#') {
                   10856:       numlinepar++;
                   10857:       fputs(line,stdout);
                   10858:       fputs(line,ficparo);
                   10859:       fputs(line,ficlog);
                   10860:       continue;
                   10861:     }else
                   10862:       break;
                   10863:   }
1.223     brouard  10864:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10865:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10866:     if (num_filled != 11) {
                   10867:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10868:       printf("but line=%s\n",line);
1.197     brouard  10869:     }
1.223     brouard  10870:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10871:   }
1.203     brouard  10872:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10873:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10874:   /* Third parameter line */
                   10875:   while(fgets(line, MAXLINE, ficpar)) {
                   10876:     /* If line starts with a # it is a comment */
                   10877:     if (line[0] == '#') {
                   10878:       numlinepar++;
                   10879:       fputs(line,stdout);
                   10880:       fputs(line,ficparo);
                   10881:       fputs(line,ficlog);
                   10882:       continue;
                   10883:     }else
                   10884:       break;
                   10885:   }
1.201     brouard  10886:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10887:     if (num_filled == 0){
                   10888:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10889:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10890:       model[0]='\0';
                   10891:       goto end;
                   10892:     } else if (num_filled != 1){
1.197     brouard  10893:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10894:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10895:       model[0]='\0';
                   10896:       goto end;
                   10897:     }
                   10898:     else{
                   10899:       if (model[0]=='+'){
                   10900:        for(i=1; i<=strlen(model);i++)
                   10901:          modeltemp[i-1]=model[i];
1.201     brouard  10902:        strcpy(model,modeltemp); 
1.197     brouard  10903:       }
                   10904:     }
1.199     brouard  10905:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10906:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10907:   }
                   10908:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10909:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10910:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10911:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10912:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10913:   fflush(ficlog);
1.190     brouard  10914:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10915:   if(model[0]=='#'){
1.187     brouard  10916:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10917:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10918:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10919:     if(mle != -1){
                   10920:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10921:       exit(1);
                   10922:     }
                   10923:   }
1.126     brouard  10924:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10925:     ungetc(c,ficpar);
                   10926:     fgets(line, MAXLINE, ficpar);
                   10927:     numlinepar++;
1.195     brouard  10928:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10929:       z[0]=line[1];
                   10930:     }
                   10931:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10932:     fputs(line, stdout);
                   10933:     //puts(line);
1.126     brouard  10934:     fputs(line,ficparo);
                   10935:     fputs(line,ficlog);
                   10936:   }
                   10937:   ungetc(c,ficpar);
                   10938: 
                   10939:    
1.145     brouard  10940:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10941:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10942:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10943:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10944:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10945:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10946:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10947:   */
                   10948:   if (strlen(model)>1) 
1.187     brouard  10949:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10950:   else
1.187     brouard  10951:     ncovmodel=2; /* Constant and age */
1.133     brouard  10952:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10953:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10954:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10955:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10956:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10957:     fflush(stdout);
                   10958:     fclose (ficlog);
                   10959:     goto end;
                   10960:   }
1.126     brouard  10961:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10962:   delti=delti3[1][1];
                   10963:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10964:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10965: /* We could also provide initial parameters values giving by simple logistic regression 
                   10966:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10967:       /* for(i=1;i<nlstate;i++){ */
                   10968:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10969:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10970:       /* } */
1.126     brouard  10971:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10972:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10973:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10974:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10975:     fclose (ficparo);
                   10976:     fclose (ficlog);
                   10977:     goto end;
                   10978:     exit(0);
1.220     brouard  10979:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10980:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10981:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10982:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10983:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10984:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10985:     hess=matrix(1,npar,1,npar);
1.220     brouard  10986:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10987:     /* Read guessed parameters */
1.126     brouard  10988:     /* Reads comments: lines beginning with '#' */
                   10989:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10990:       ungetc(c,ficpar);
                   10991:       fgets(line, MAXLINE, ficpar);
                   10992:       numlinepar++;
1.141     brouard  10993:       fputs(line,stdout);
1.126     brouard  10994:       fputs(line,ficparo);
                   10995:       fputs(line,ficlog);
                   10996:     }
                   10997:     ungetc(c,ficpar);
                   10998:     
                   10999:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11000:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11001:     for(i=1; i <=nlstate; i++){
1.234     brouard  11002:       j=0;
1.126     brouard  11003:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11004:        if(jj==i) continue;
                   11005:        j++;
                   11006:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11007:        if ((i1 != i) || (j1 != jj)){
                   11008:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11009: It might be a problem of design; if ncovcol and the model are correct\n \
                   11010: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11011:          exit(1);
                   11012:        }
                   11013:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11014:        if(mle==1)
                   11015:          printf("%1d%1d",i,jj);
                   11016:        fprintf(ficlog,"%1d%1d",i,jj);
                   11017:        for(k=1; k<=ncovmodel;k++){
                   11018:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11019:          if(mle==1){
                   11020:            printf(" %lf",param[i][j][k]);
                   11021:            fprintf(ficlog," %lf",param[i][j][k]);
                   11022:          }
                   11023:          else
                   11024:            fprintf(ficlog," %lf",param[i][j][k]);
                   11025:          fprintf(ficparo," %lf",param[i][j][k]);
                   11026:        }
                   11027:        fscanf(ficpar,"\n");
                   11028:        numlinepar++;
                   11029:        if(mle==1)
                   11030:          printf("\n");
                   11031:        fprintf(ficlog,"\n");
                   11032:        fprintf(ficparo,"\n");
1.126     brouard  11033:       }
                   11034:     }  
                   11035:     fflush(ficlog);
1.234     brouard  11036:     
1.251     brouard  11037:     /* Reads parameters values */
1.126     brouard  11038:     p=param[1][1];
1.251     brouard  11039:     pstart=paramstart[1][1];
1.126     brouard  11040:     
                   11041:     /* Reads comments: lines beginning with '#' */
                   11042:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11043:       ungetc(c,ficpar);
                   11044:       fgets(line, MAXLINE, ficpar);
                   11045:       numlinepar++;
1.141     brouard  11046:       fputs(line,stdout);
1.126     brouard  11047:       fputs(line,ficparo);
                   11048:       fputs(line,ficlog);
                   11049:     }
                   11050:     ungetc(c,ficpar);
                   11051: 
                   11052:     for(i=1; i <=nlstate; i++){
                   11053:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11054:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11055:        if ( (i1-i) * (j1-j) != 0){
                   11056:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11057:          exit(1);
                   11058:        }
                   11059:        printf("%1d%1d",i,j);
                   11060:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11061:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11062:        for(k=1; k<=ncovmodel;k++){
                   11063:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11064:          printf(" %le",delti3[i][j][k]);
                   11065:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11066:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11067:        }
                   11068:        fscanf(ficpar,"\n");
                   11069:        numlinepar++;
                   11070:        printf("\n");
                   11071:        fprintf(ficparo,"\n");
                   11072:        fprintf(ficlog,"\n");
1.126     brouard  11073:       }
                   11074:     }
                   11075:     fflush(ficlog);
1.234     brouard  11076:     
1.145     brouard  11077:     /* Reads covariance matrix */
1.126     brouard  11078:     delti=delti3[1][1];
1.220     brouard  11079:                
                   11080:                
1.126     brouard  11081:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11082:                
1.126     brouard  11083:     /* Reads comments: lines beginning with '#' */
                   11084:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11085:       ungetc(c,ficpar);
                   11086:       fgets(line, MAXLINE, ficpar);
                   11087:       numlinepar++;
1.141     brouard  11088:       fputs(line,stdout);
1.126     brouard  11089:       fputs(line,ficparo);
                   11090:       fputs(line,ficlog);
                   11091:     }
                   11092:     ungetc(c,ficpar);
1.220     brouard  11093:                
1.126     brouard  11094:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11095:     hess=matrix(1,npar,1,npar);
1.131     brouard  11096:     for(i=1; i <=npar; i++)
                   11097:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11098:                
1.194     brouard  11099:     /* Scans npar lines */
1.126     brouard  11100:     for(i=1; i <=npar; i++){
1.226     brouard  11101:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11102:       if(count != 3){
1.226     brouard  11103:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11104: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11105: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11106:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11107: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11108: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11109:        exit(1);
1.220     brouard  11110:       }else{
1.226     brouard  11111:        if(mle==1)
                   11112:          printf("%1d%1d%d",i1,j1,jk);
                   11113:       }
                   11114:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11115:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11116:       for(j=1; j <=i; j++){
1.226     brouard  11117:        fscanf(ficpar," %le",&matcov[i][j]);
                   11118:        if(mle==1){
                   11119:          printf(" %.5le",matcov[i][j]);
                   11120:        }
                   11121:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11122:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11123:       }
                   11124:       fscanf(ficpar,"\n");
                   11125:       numlinepar++;
                   11126:       if(mle==1)
1.220     brouard  11127:                                printf("\n");
1.126     brouard  11128:       fprintf(ficlog,"\n");
                   11129:       fprintf(ficparo,"\n");
                   11130:     }
1.194     brouard  11131:     /* End of read covariance matrix npar lines */
1.126     brouard  11132:     for(i=1; i <=npar; i++)
                   11133:       for(j=i+1;j<=npar;j++)
1.226     brouard  11134:        matcov[i][j]=matcov[j][i];
1.126     brouard  11135:     
                   11136:     if(mle==1)
                   11137:       printf("\n");
                   11138:     fprintf(ficlog,"\n");
                   11139:     
                   11140:     fflush(ficlog);
                   11141:     
                   11142:     /*-------- Rewriting parameter file ----------*/
                   11143:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11144:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11145:     strcat(rfileres,".");    /* */
                   11146:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11147:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11148:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11149:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11150:     }
                   11151:     fprintf(ficres,"#%s\n",version);
                   11152:   }    /* End of mle != -3 */
1.218     brouard  11153:   
1.186     brouard  11154:   /*  Main data
                   11155:    */
1.126     brouard  11156:   n= lastobs;
                   11157:   num=lvector(1,n);
                   11158:   moisnais=vector(1,n);
                   11159:   annais=vector(1,n);
                   11160:   moisdc=vector(1,n);
                   11161:   andc=vector(1,n);
1.220     brouard  11162:   weight=vector(1,n);
1.126     brouard  11163:   agedc=vector(1,n);
                   11164:   cod=ivector(1,n);
1.220     brouard  11165:   for(i=1;i<=n;i++){
1.234     brouard  11166:     num[i]=0;
                   11167:     moisnais[i]=0;
                   11168:     annais[i]=0;
                   11169:     moisdc[i]=0;
                   11170:     andc[i]=0;
                   11171:     agedc[i]=0;
                   11172:     cod[i]=0;
                   11173:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11174:   }
1.126     brouard  11175:   mint=matrix(1,maxwav,1,n);
                   11176:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11177:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11178:   tab=ivector(1,NCOVMAX);
1.144     brouard  11179:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11180:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11181: 
1.136     brouard  11182:   /* Reads data from file datafile */
                   11183:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11184:     goto end;
                   11185: 
                   11186:   /* Calculation of the number of parameters from char model */
1.234     brouard  11187:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11188:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11189:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11190:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11191:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11192:   */
                   11193:   
                   11194:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11195:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11196:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11197:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11198:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11199:   TvarF=ivector(1,NCOVMAX); /*  */
                   11200:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11201:   TvarV=ivector(1,NCOVMAX); /*  */
                   11202:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11203:   TvarA=ivector(1,NCOVMAX); /*  */
                   11204:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11205:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11206:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11207:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11208:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11209:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11210:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11211:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11212:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11213: 
1.230     brouard  11214:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11215:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11216:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11217:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11218:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11219:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11220:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11221:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11222:   */
                   11223:   /* For model-covariate k tells which data-covariate to use but
                   11224:     because this model-covariate is a construction we invent a new column
                   11225:     ncovcol + k1
                   11226:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11227:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11228:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11229:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11230:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11231:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11232:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11233:   */
1.145     brouard  11234:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11235:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11236:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11237:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11238:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11239:                         4 covariates (3 plus signs)
                   11240:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11241:                      */  
1.230     brouard  11242:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11243:                                * individual dummy, fixed or varying:
                   11244:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11245:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11246:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11247:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11248:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11249:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11250:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11251:                                * individual quantitative, fixed or varying:
                   11252:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11253:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11254:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11255: /* Main decodemodel */
                   11256: 
1.187     brouard  11257: 
1.223     brouard  11258:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11259:     goto end;
                   11260: 
1.137     brouard  11261:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11262:     nbwarn++;
                   11263:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11264:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11265:   }
1.136     brouard  11266:     /*  if(mle==1){*/
1.137     brouard  11267:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11268:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11269:   }
                   11270: 
                   11271:     /*-calculation of age at interview from date of interview and age at death -*/
                   11272:   agev=matrix(1,maxwav,1,imx);
                   11273: 
                   11274:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11275:     goto end;
                   11276: 
1.126     brouard  11277: 
1.136     brouard  11278:   agegomp=(int)agemin;
                   11279:   free_vector(moisnais,1,n);
                   11280:   free_vector(annais,1,n);
1.126     brouard  11281:   /* free_matrix(mint,1,maxwav,1,n);
                   11282:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11283:   /* free_vector(moisdc,1,n); */
                   11284:   /* free_vector(andc,1,n); */
1.145     brouard  11285:   /* */
                   11286:   
1.126     brouard  11287:   wav=ivector(1,imx);
1.214     brouard  11288:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11289:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11290:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11291:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11292:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11293:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11294:    
                   11295:   /* Concatenates waves */
1.214     brouard  11296:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11297:      Death is a valid wave (if date is known).
                   11298:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11299:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11300:      and mw[mi+1][i]. dh depends on stepm.
                   11301:   */
                   11302: 
1.126     brouard  11303:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11304:   /* Concatenates waves */
1.145     brouard  11305:  
1.215     brouard  11306:   free_vector(moisdc,1,n);
                   11307:   free_vector(andc,1,n);
                   11308: 
1.126     brouard  11309:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11310:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11311:   ncodemax[1]=1;
1.145     brouard  11312:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11313:   cptcoveff=0;
1.220     brouard  11314:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11315:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11316:   }
                   11317:   
                   11318:   ncovcombmax=pow(2,cptcoveff);
                   11319:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11320:   for(i=1;i<ncovcombmax;i++)
                   11321:     invalidvarcomb[i]=0;
                   11322:   
1.211     brouard  11323:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11324:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11325:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11326:   
1.200     brouard  11327:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11328:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11329:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11330:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11331:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11332:    * (currently 0 or 1) in the data.
                   11333:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11334:    * corresponding modality (h,j).
                   11335:    */
                   11336: 
1.145     brouard  11337:   h=0;
                   11338:   /*if (cptcovn > 0) */
1.126     brouard  11339:   m=pow(2,cptcoveff);
                   11340:  
1.144     brouard  11341:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11342:           * For k=4 covariates, h goes from 1 to m=2**k
                   11343:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11344:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11345:           *     h\k   1     2     3     4
1.143     brouard  11346:           *______________________________  
                   11347:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11348:           *     2     2     1     1     1
                   11349:           *     3 i=2 1     2     1     1
                   11350:           *     4     2     2     1     1
                   11351:           *     5 i=3 1 i=2 1     2     1
                   11352:           *     6     2     1     2     1
                   11353:           *     7 i=4 1     2     2     1
                   11354:           *     8     2     2     2     1
1.197     brouard  11355:           *     9 i=5 1 i=3 1 i=2 1     2
                   11356:           *    10     2     1     1     2
                   11357:           *    11 i=6 1     2     1     2
                   11358:           *    12     2     2     1     2
                   11359:           *    13 i=7 1 i=4 1     2     2    
                   11360:           *    14     2     1     2     2
                   11361:           *    15 i=8 1     2     2     2
                   11362:           *    16     2     2     2     2
1.143     brouard  11363:           */
1.212     brouard  11364:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11365:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11366:      * and the value of each covariate?
                   11367:      * V1=1, V2=1, V3=2, V4=1 ?
                   11368:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11369:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11370:      * In order to get the real value in the data, we use nbcode
                   11371:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11372:      * We are keeping this crazy system in order to be able (in the future?) 
                   11373:      * to have more than 2 values (0 or 1) for a covariate.
                   11374:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11375:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11376:      *              bbbbbbbb
                   11377:      *              76543210     
                   11378:      *   h-1        00000101 (6-1=5)
1.219     brouard  11379:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11380:      *           &
                   11381:      *     1        00000001 (1)
1.219     brouard  11382:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11383:      *          +1= 00000001 =1 
1.211     brouard  11384:      *
                   11385:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11386:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11387:      *    >>k'            11
                   11388:      *          &   00000001
                   11389:      *            = 00000001
                   11390:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11391:      * Reverse h=6 and m=16?
                   11392:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11393:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11394:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11395:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11396:      * V3=decodtabm(14,3,2**4)=2
                   11397:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11398:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11399:      *          &1 000000001
                   11400:      *           = 000000001
                   11401:      *         +1= 000000010 =2
                   11402:      *                  2211
                   11403:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11404:      *                  V3=2
1.220     brouard  11405:                 * codtabm and decodtabm are identical
1.211     brouard  11406:      */
                   11407: 
1.145     brouard  11408: 
                   11409:  free_ivector(Ndum,-1,NCOVMAX);
                   11410: 
                   11411: 
1.126     brouard  11412:     
1.186     brouard  11413:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11414:   strcpy(optionfilegnuplot,optionfilefiname);
                   11415:   if(mle==-3)
1.201     brouard  11416:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11417:   strcat(optionfilegnuplot,".gp");
                   11418: 
                   11419:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11420:     printf("Problem with file %s",optionfilegnuplot);
                   11421:   }
                   11422:   else{
1.204     brouard  11423:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11424:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11425:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11426:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11427:   }
                   11428:   /*  fclose(ficgp);*/
1.186     brouard  11429: 
                   11430: 
                   11431:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11432: 
                   11433:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11434:   if(mle==-3)
1.201     brouard  11435:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11436:   strcat(optionfilehtm,".htm");
                   11437:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11438:     printf("Problem with %s \n",optionfilehtm);
                   11439:     exit(0);
1.126     brouard  11440:   }
                   11441: 
                   11442:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11443:   strcat(optionfilehtmcov,"-cov.htm");
                   11444:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11445:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11446:   }
                   11447:   else{
                   11448:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11449: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11450: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11451:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11452:   }
                   11453: 
1.213     brouard  11454:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11455: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11456: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11457: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11458: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11459: \n\
                   11460: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11461:  <ul><li><h4>Parameter files</h4>\n\
                   11462:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11463:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11464:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11465:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11466:  - Date and time at start: %s</ul>\n",\
                   11467:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11468:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11469:          fileres,fileres,\
                   11470:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11471:   fflush(fichtm);
                   11472: 
                   11473:   strcpy(pathr,path);
                   11474:   strcat(pathr,optionfilefiname);
1.184     brouard  11475: #ifdef WIN32
                   11476:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11477: #else
1.126     brouard  11478:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11479: #endif
                   11480:          
1.126     brouard  11481:   
1.220     brouard  11482:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11483:                 and for any valid combination of covariates
1.126     brouard  11484:      and prints on file fileres'p'. */
1.251     brouard  11485:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11486:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11487: 
                   11488:   fprintf(fichtm,"\n");
1.274   ! brouard  11489:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%f \n<li>Interval for the elementary matrix (in month): stepm=%d",\
        !          11490:          ftol, stepm);
        !          11491:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
        !          11492:   ncurrv=1;
        !          11493:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
        !          11494:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
        !          11495:   ncurrv=i;
        !          11496:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
        !          11497:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
        !          11498:   ncurrv=i;
        !          11499:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
        !          11500:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
        !          11501:   ncurrv=i;
        !          11502:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
        !          11503:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
        !          11504:           nlstate, ndeath, maxwav, mle, weightopt);
        !          11505: 
        !          11506:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
        !          11507: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
        !          11508: 
        !          11509:   
        !          11510:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11511: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11512: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274   ! brouard  11513:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11514:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11515:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11516:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11517:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11518:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11519: 
1.126     brouard  11520:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11521:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11522:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11523: 
                   11524:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11525:   /* For mortality only */
1.126     brouard  11526:   if (mle==-3){
1.136     brouard  11527:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11528:     for(i=1;i<=NDIM;i++)
                   11529:       for(j=1;j<=NDIM;j++)
                   11530:        ximort[i][j]=0.;
1.186     brouard  11531:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11532:     cens=ivector(1,n);
                   11533:     ageexmed=vector(1,n);
                   11534:     agecens=vector(1,n);
                   11535:     dcwave=ivector(1,n);
1.223     brouard  11536:                
1.126     brouard  11537:     for (i=1; i<=imx; i++){
                   11538:       dcwave[i]=-1;
                   11539:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11540:        if (s[m][i]>nlstate) {
                   11541:          dcwave[i]=m;
                   11542:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11543:          break;
                   11544:        }
1.126     brouard  11545:     }
1.226     brouard  11546:     
1.126     brouard  11547:     for (i=1; i<=imx; i++) {
                   11548:       if (wav[i]>0){
1.226     brouard  11549:        ageexmed[i]=agev[mw[1][i]][i];
                   11550:        j=wav[i];
                   11551:        agecens[i]=1.; 
                   11552:        
                   11553:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11554:          agecens[i]=agev[mw[j][i]][i];
                   11555:          cens[i]= 1;
                   11556:        }else if (ageexmed[i]< 1) 
                   11557:          cens[i]= -1;
                   11558:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11559:          cens[i]=0 ;
1.126     brouard  11560:       }
                   11561:       else cens[i]=-1;
                   11562:     }
                   11563:     
                   11564:     for (i=1;i<=NDIM;i++) {
                   11565:       for (j=1;j<=NDIM;j++)
1.226     brouard  11566:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11567:     }
                   11568:     
1.145     brouard  11569:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11570:     /*printf("%lf %lf", p[1], p[2]);*/
                   11571:     
                   11572:     
1.136     brouard  11573: #ifdef GSL
                   11574:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11575: #else
1.126     brouard  11576:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11577: #endif
1.201     brouard  11578:     strcpy(filerespow,"POW-MORT_"); 
                   11579:     strcat(filerespow,fileresu);
1.126     brouard  11580:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11581:       printf("Problem with resultfile: %s\n", filerespow);
                   11582:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11583:     }
1.136     brouard  11584: #ifdef GSL
                   11585:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11586: #else
1.126     brouard  11587:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11588: #endif
1.126     brouard  11589:     /*  for (i=1;i<=nlstate;i++)
                   11590:        for(j=1;j<=nlstate+ndeath;j++)
                   11591:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11592:     */
                   11593:     fprintf(ficrespow,"\n");
1.136     brouard  11594: #ifdef GSL
                   11595:     /* gsl starts here */ 
                   11596:     T = gsl_multimin_fminimizer_nmsimplex;
                   11597:     gsl_multimin_fminimizer *sfm = NULL;
                   11598:     gsl_vector *ss, *x;
                   11599:     gsl_multimin_function minex_func;
                   11600: 
                   11601:     /* Initial vertex size vector */
                   11602:     ss = gsl_vector_alloc (NDIM);
                   11603:     
                   11604:     if (ss == NULL){
                   11605:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11606:     }
                   11607:     /* Set all step sizes to 1 */
                   11608:     gsl_vector_set_all (ss, 0.001);
                   11609: 
                   11610:     /* Starting point */
1.126     brouard  11611:     
1.136     brouard  11612:     x = gsl_vector_alloc (NDIM);
                   11613:     
                   11614:     if (x == NULL){
                   11615:       gsl_vector_free(ss);
                   11616:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11617:     }
                   11618:   
                   11619:     /* Initialize method and iterate */
                   11620:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11621:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11622:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11623:     gsl_vector_set(x, 0, p[1]);
                   11624:     gsl_vector_set(x, 1, p[2]);
                   11625: 
                   11626:     minex_func.f = &gompertz_f;
                   11627:     minex_func.n = NDIM;
                   11628:     minex_func.params = (void *)&p; /* ??? */
                   11629:     
                   11630:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11631:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11632:     
                   11633:     printf("Iterations beginning .....\n\n");
                   11634:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11635: 
                   11636:     iteri=0;
                   11637:     while (rval == GSL_CONTINUE){
                   11638:       iteri++;
                   11639:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11640:       
                   11641:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11642:       fflush(0);
                   11643:       
                   11644:       if (status) 
                   11645:         break;
                   11646:       
                   11647:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11648:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11649:       
                   11650:       if (rval == GSL_SUCCESS)
                   11651:         printf ("converged to a local maximum at\n");
                   11652:       
                   11653:       printf("%5d ", iteri);
                   11654:       for (it = 0; it < NDIM; it++){
                   11655:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11656:       }
                   11657:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11658:     }
                   11659:     
                   11660:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11661:     
                   11662:     gsl_vector_free(x); /* initial values */
                   11663:     gsl_vector_free(ss); /* inital step size */
                   11664:     for (it=0; it<NDIM; it++){
                   11665:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11666:       fprintf(ficrespow," %.12lf", p[it]);
                   11667:     }
                   11668:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11669: #endif
                   11670: #ifdef POWELL
                   11671:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11672: #endif  
1.126     brouard  11673:     fclose(ficrespow);
                   11674:     
1.203     brouard  11675:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11676: 
                   11677:     for(i=1; i <=NDIM; i++)
                   11678:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11679:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11680:     
                   11681:     printf("\nCovariance matrix\n ");
1.203     brouard  11682:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11683:     for(i=1; i <=NDIM; i++) {
                   11684:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11685:                                printf("%f ",matcov[i][j]);
                   11686:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11687:       }
1.203     brouard  11688:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11689:     }
                   11690:     
                   11691:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11692:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11693:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11694:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11695:     }
1.126     brouard  11696:     lsurv=vector(1,AGESUP);
                   11697:     lpop=vector(1,AGESUP);
                   11698:     tpop=vector(1,AGESUP);
                   11699:     lsurv[agegomp]=100000;
                   11700:     
                   11701:     for (k=agegomp;k<=AGESUP;k++) {
                   11702:       agemortsup=k;
                   11703:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11704:     }
                   11705:     
                   11706:     for (k=agegomp;k<agemortsup;k++)
                   11707:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11708:     
                   11709:     for (k=agegomp;k<agemortsup;k++){
                   11710:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11711:       sumlpop=sumlpop+lpop[k];
                   11712:     }
                   11713:     
                   11714:     tpop[agegomp]=sumlpop;
                   11715:     for (k=agegomp;k<(agemortsup-3);k++){
                   11716:       /*  tpop[k+1]=2;*/
                   11717:       tpop[k+1]=tpop[k]-lpop[k];
                   11718:     }
                   11719:     
                   11720:     
                   11721:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11722:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11723:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11724:     
                   11725:     
                   11726:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11727:                ageminpar=50;
                   11728:                agemaxpar=100;
1.194     brouard  11729:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11730:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11731: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11732: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11733:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11734: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11735: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11736:     }else{
                   11737:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11738:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11739:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11740:                }
1.201     brouard  11741:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11742:                     stepm, weightopt,\
                   11743:                     model,imx,p,matcov,agemortsup);
                   11744:     
                   11745:     free_vector(lsurv,1,AGESUP);
                   11746:     free_vector(lpop,1,AGESUP);
                   11747:     free_vector(tpop,1,AGESUP);
1.220     brouard  11748:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11749:     free_ivector(cens,1,n);
                   11750:     free_vector(agecens,1,n);
                   11751:     free_ivector(dcwave,1,n);
1.220     brouard  11752: #ifdef GSL
1.136     brouard  11753: #endif
1.186     brouard  11754:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11755:   /* Standard  */
                   11756:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11757:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11758:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11759:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11760:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11761:     for (k=1; k<=npar;k++)
                   11762:       printf(" %d %8.5f",k,p[k]);
                   11763:     printf("\n");
1.205     brouard  11764:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11765:       /* mlikeli uses func not funcone */
1.247     brouard  11766:       /* for(i=1;i<nlstate;i++){ */
                   11767:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11768:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11769:       /* } */
1.205     brouard  11770:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11771:     }
                   11772:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11773:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11774:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11775:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11776:     }
                   11777:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11778:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11779:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11780:     for (k=1; k<=npar;k++)
                   11781:       printf(" %d %8.5f",k,p[k]);
                   11782:     printf("\n");
                   11783:     
                   11784:     /*--------- results files --------------*/
1.224     brouard  11785:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11786:     
                   11787:     
                   11788:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11789:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11790:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11791:     for(i=1,jk=1; i <=nlstate; i++){
                   11792:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11793:        if (k != i) {
                   11794:          printf("%d%d ",i,k);
                   11795:          fprintf(ficlog,"%d%d ",i,k);
                   11796:          fprintf(ficres,"%1d%1d ",i,k);
                   11797:          for(j=1; j <=ncovmodel; j++){
                   11798:            printf("%12.7f ",p[jk]);
                   11799:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11800:            fprintf(ficres,"%12.7f ",p[jk]);
                   11801:            jk++; 
                   11802:          }
                   11803:          printf("\n");
                   11804:          fprintf(ficlog,"\n");
                   11805:          fprintf(ficres,"\n");
                   11806:        }
1.126     brouard  11807:       }
                   11808:     }
1.203     brouard  11809:     if(mle != 0){
                   11810:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11811:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11812:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11813:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11814:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11815:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11816:        for(k=1; k <=(nlstate+ndeath); k++){
                   11817:          if (k != i) {
                   11818:            printf("%d%d ",i,k);
                   11819:            fprintf(ficlog,"%d%d ",i,k);
                   11820:            for(j=1; j <=ncovmodel; j++){
                   11821:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11822:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11823:              jk++; 
                   11824:            }
                   11825:            printf("\n");
                   11826:            fprintf(ficlog,"\n");
                   11827:          }
                   11828:        }
1.193     brouard  11829:       }
1.203     brouard  11830:     } /* end of hesscov and Wald tests */
1.225     brouard  11831:     
1.203     brouard  11832:     /*  */
1.126     brouard  11833:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11834:     printf("# Scales (for hessian or gradient estimation)\n");
                   11835:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11836:     for(i=1,jk=1; i <=nlstate; i++){
                   11837:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11838:        if (j!=i) {
                   11839:          fprintf(ficres,"%1d%1d",i,j);
                   11840:          printf("%1d%1d",i,j);
                   11841:          fprintf(ficlog,"%1d%1d",i,j);
                   11842:          for(k=1; k<=ncovmodel;k++){
                   11843:            printf(" %.5e",delti[jk]);
                   11844:            fprintf(ficlog," %.5e",delti[jk]);
                   11845:            fprintf(ficres," %.5e",delti[jk]);
                   11846:            jk++;
                   11847:          }
                   11848:          printf("\n");
                   11849:          fprintf(ficlog,"\n");
                   11850:          fprintf(ficres,"\n");
                   11851:        }
1.126     brouard  11852:       }
                   11853:     }
                   11854:     
                   11855:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11856:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11857:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11858:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11859:     /* # 121 Var(a12)\n\ */
                   11860:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11861:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11862:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11863:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11864:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11865:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11866:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11867:     
                   11868:     
                   11869:     /* Just to have a covariance matrix which will be more understandable
                   11870:        even is we still don't want to manage dictionary of variables
                   11871:     */
                   11872:     for(itimes=1;itimes<=2;itimes++){
                   11873:       jj=0;
                   11874:       for(i=1; i <=nlstate; i++){
1.225     brouard  11875:        for(j=1; j <=nlstate+ndeath; j++){
                   11876:          if(j==i) continue;
                   11877:          for(k=1; k<=ncovmodel;k++){
                   11878:            jj++;
                   11879:            ca[0]= k+'a'-1;ca[1]='\0';
                   11880:            if(itimes==1){
                   11881:              if(mle>=1)
                   11882:                printf("#%1d%1d%d",i,j,k);
                   11883:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11884:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11885:            }else{
                   11886:              if(mle>=1)
                   11887:                printf("%1d%1d%d",i,j,k);
                   11888:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11889:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11890:            }
                   11891:            ll=0;
                   11892:            for(li=1;li <=nlstate; li++){
                   11893:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11894:                if(lj==li) continue;
                   11895:                for(lk=1;lk<=ncovmodel;lk++){
                   11896:                  ll++;
                   11897:                  if(ll<=jj){
                   11898:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11899:                    if(ll<jj){
                   11900:                      if(itimes==1){
                   11901:                        if(mle>=1)
                   11902:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11903:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11904:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11905:                      }else{
                   11906:                        if(mle>=1)
                   11907:                          printf(" %.5e",matcov[jj][ll]); 
                   11908:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11909:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11910:                      }
                   11911:                    }else{
                   11912:                      if(itimes==1){
                   11913:                        if(mle>=1)
                   11914:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11915:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11916:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11917:                      }else{
                   11918:                        if(mle>=1)
                   11919:                          printf(" %.7e",matcov[jj][ll]); 
                   11920:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11921:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11922:                      }
                   11923:                    }
                   11924:                  }
                   11925:                } /* end lk */
                   11926:              } /* end lj */
                   11927:            } /* end li */
                   11928:            if(mle>=1)
                   11929:              printf("\n");
                   11930:            fprintf(ficlog,"\n");
                   11931:            fprintf(ficres,"\n");
                   11932:            numlinepar++;
                   11933:          } /* end k*/
                   11934:        } /*end j */
1.126     brouard  11935:       } /* end i */
                   11936:     } /* end itimes */
                   11937:     
                   11938:     fflush(ficlog);
                   11939:     fflush(ficres);
1.225     brouard  11940:     while(fgets(line, MAXLINE, ficpar)) {
                   11941:       /* If line starts with a # it is a comment */
                   11942:       if (line[0] == '#') {
                   11943:        numlinepar++;
                   11944:        fputs(line,stdout);
                   11945:        fputs(line,ficparo);
                   11946:        fputs(line,ficlog);
                   11947:        continue;
                   11948:       }else
                   11949:        break;
                   11950:     }
                   11951:     
1.209     brouard  11952:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11953:     /*   ungetc(c,ficpar); */
                   11954:     /*   fgets(line, MAXLINE, ficpar); */
                   11955:     /*   fputs(line,stdout); */
                   11956:     /*   fputs(line,ficparo); */
                   11957:     /* } */
                   11958:     /* ungetc(c,ficpar); */
1.126     brouard  11959:     
                   11960:     estepm=0;
1.209     brouard  11961:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11962:       
                   11963:       if (num_filled != 6) {
                   11964:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11965:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11966:        goto end;
                   11967:       }
                   11968:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11969:     }
                   11970:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11971:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11972:     
1.209     brouard  11973:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11974:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11975:     if (fage <= 2) {
                   11976:       bage = ageminpar;
                   11977:       fage = agemaxpar;
                   11978:     }
                   11979:     
                   11980:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11981:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11982:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11983:                
1.186     brouard  11984:     /* Other stuffs, more or less useful */    
1.254     brouard  11985:     while(fgets(line, MAXLINE, ficpar)) {
                   11986:       /* If line starts with a # it is a comment */
                   11987:       if (line[0] == '#') {
                   11988:        numlinepar++;
                   11989:        fputs(line,stdout);
                   11990:        fputs(line,ficparo);
                   11991:        fputs(line,ficlog);
                   11992:        continue;
                   11993:       }else
                   11994:        break;
                   11995:     }
                   11996: 
                   11997:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11998:       
                   11999:       if (num_filled != 7) {
                   12000:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12001:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12002:        goto end;
                   12003:       }
                   12004:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12005:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12006:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12007:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12008:     }
1.254     brouard  12009: 
                   12010:     while(fgets(line, MAXLINE, ficpar)) {
                   12011:       /* If line starts with a # it is a comment */
                   12012:       if (line[0] == '#') {
                   12013:        numlinepar++;
                   12014:        fputs(line,stdout);
                   12015:        fputs(line,ficparo);
                   12016:        fputs(line,ficlog);
                   12017:        continue;
                   12018:       }else
                   12019:        break;
1.126     brouard  12020:     }
                   12021:     
                   12022:     
                   12023:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12024:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12025:     
1.254     brouard  12026:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12027:       if (num_filled != 1) {
                   12028:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12029:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12030:        goto end;
                   12031:       }
                   12032:       printf("pop_based=%d\n",popbased);
                   12033:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12034:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12035:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12036:     }
                   12037:      
1.258     brouard  12038:     /* Results */
                   12039:     nresult=0;
                   12040:     do{
                   12041:       if(!fgets(line, MAXLINE, ficpar)){
                   12042:        endishere=1;
                   12043:        parameterline=14;
                   12044:       }else if (line[0] == '#') {
                   12045:        /* If line starts with a # it is a comment */
1.254     brouard  12046:        numlinepar++;
                   12047:        fputs(line,stdout);
                   12048:        fputs(line,ficparo);
                   12049:        fputs(line,ficlog);
                   12050:        continue;
1.258     brouard  12051:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12052:        parameterline=11;
                   12053:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12054:        parameterline=12;
                   12055:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12056:        parameterline=13;
                   12057:       else{
                   12058:        parameterline=14;
1.254     brouard  12059:       }
1.258     brouard  12060:       switch (parameterline){ 
                   12061:       case 11:
                   12062:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12063:          if (num_filled != 8) {
                   12064:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12065:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12066:            goto end;
                   12067:          }
                   12068:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12069:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12070:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12071:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12072:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12073:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12074:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12075: 
1.258     brouard  12076:        }
1.254     brouard  12077:        break;
1.258     brouard  12078:       case 12:
                   12079:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12080:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12081:          if (num_filled != 8) {
1.262     brouard  12082:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12083:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12084:            goto end;
                   12085:          }
                   12086:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12087:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12088:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12089:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12090:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12091:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12092:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12093:        }
1.230     brouard  12094:        break;
1.258     brouard  12095:       case 13:
                   12096:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12097:          if (num_filled == 0){
                   12098:            resultline[0]='\0';
                   12099:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12100:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12101:            break;
                   12102:          } else if (num_filled != 1){
                   12103:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12104:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12105:          }
                   12106:          nresult++; /* Sum of resultlines */
                   12107:          printf("Result %d: result=%s\n",nresult, resultline);
                   12108:          if(nresult > MAXRESULTLINES){
                   12109:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12110:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12111:            goto end;
                   12112:          }
                   12113:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12114:          fprintf(ficparo,"result: %s\n",resultline);
                   12115:          fprintf(ficres,"result: %s\n",resultline);
                   12116:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12117:          break;
1.258     brouard  12118:        case 14: 
1.259     brouard  12119:          if(ncovmodel >2 && nresult==0 ){
                   12120:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12121:            goto end;
                   12122:          }
1.259     brouard  12123:          break;
1.258     brouard  12124:        default:
                   12125:          nresult=1;
                   12126:          decoderesult(".",nresult ); /* No covariate */
                   12127:        }
                   12128:       } /* End switch parameterline */
                   12129:     }while(endishere==0); /* End do */
1.126     brouard  12130:     
1.230     brouard  12131:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12132:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12133:     
                   12134:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12135:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12136:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12137: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12138: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12139:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12140: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12141: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12142:     }else{
1.270     brouard  12143:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12144:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12145:     }
                   12146:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12147:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12148:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12149:                
1.225     brouard  12150:     /*------------ free_vector  -------------*/
                   12151:     /*  chdir(path); */
1.220     brouard  12152:                
1.215     brouard  12153:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12154:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12155:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12156:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12157:     free_lvector(num,1,n);
                   12158:     free_vector(agedc,1,n);
                   12159:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12160:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12161:     fclose(ficparo);
                   12162:     fclose(ficres);
1.220     brouard  12163:                
                   12164:                
1.186     brouard  12165:     /* Other results (useful)*/
1.220     brouard  12166:                
                   12167:                
1.126     brouard  12168:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12169:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12170:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12171:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12172:     fclose(ficrespl);
                   12173: 
                   12174:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12175:     /*#include "hpijx.h"*/
                   12176:     hPijx(p, bage, fage);
1.145     brouard  12177:     fclose(ficrespij);
1.227     brouard  12178:     
1.220     brouard  12179:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12180:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12181:     k=1;
1.126     brouard  12182:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12183:     
1.269     brouard  12184:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12185:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12186:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12187:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12188:        for(k=1;k<=ncovcombmax;k++)
                   12189:          probs[i][j][k]=0.;
1.269     brouard  12190:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12191:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12192:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12193:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12194:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12195:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12196:          for(k=1;k<=ncovcombmax;k++)
                   12197:            mobaverages[i][j][k]=0.;
1.219     brouard  12198:       mobaverage=mobaverages;
                   12199:       if (mobilav!=0) {
1.235     brouard  12200:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12201:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12202:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12203:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12204:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12205:        }
1.269     brouard  12206:       } else if (mobilavproj !=0) {
1.235     brouard  12207:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12208:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12209:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12210:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12211:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12212:        }
1.269     brouard  12213:       }else{
                   12214:        printf("Internal error moving average\n");
                   12215:        fflush(stdout);
                   12216:        exit(1);
1.219     brouard  12217:       }
                   12218:     }/* end if moving average */
1.227     brouard  12219:     
1.126     brouard  12220:     /*---------- Forecasting ------------------*/
                   12221:     if(prevfcast==1){
                   12222:       /*    if(stepm ==1){*/
1.269     brouard  12223:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12224:     }
1.269     brouard  12225: 
                   12226:     /* Backcasting */
1.217     brouard  12227:     if(backcast==1){
1.219     brouard  12228:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12229:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12230:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12231: 
                   12232:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12233: 
                   12234:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12235: 
1.219     brouard  12236:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12237:       fclose(ficresplb);
                   12238: 
1.222     brouard  12239:       hBijx(p, bage, fage, mobaverage);
                   12240:       fclose(ficrespijb);
1.219     brouard  12241: 
1.269     brouard  12242:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12243:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12244:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12245: 
                   12246:       
1.269     brouard  12247:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12248:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12249:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12250:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12251:     }    /* end  Backcasting */
1.268     brouard  12252:  
1.186     brouard  12253:  
                   12254:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12255: 
1.215     brouard  12256:     free_ivector(wav,1,imx);
                   12257:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12258:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12259:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12260:                
                   12261:                
1.127     brouard  12262:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12263:                
1.201     brouard  12264:     strcpy(filerese,"E_");
                   12265:     strcat(filerese,fileresu);
1.126     brouard  12266:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12267:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12268:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12269:     }
1.208     brouard  12270:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12271:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12272: 
                   12273:     pstamp(ficreseij);
1.219     brouard  12274:                
1.235     brouard  12275:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12276:     if (cptcovn < 1){i1=1;}
                   12277:     
                   12278:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12279:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12280:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12281:        continue;
1.219     brouard  12282:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12283:       printf("\n#****** ");
1.225     brouard  12284:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12285:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12286:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12287:       }
                   12288:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12289:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12290:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12291:       }
                   12292:       fprintf(ficreseij,"******\n");
1.235     brouard  12293:       printf("******\n");
1.219     brouard  12294:       
                   12295:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12296:       oldm=oldms;savm=savms;
1.235     brouard  12297:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12298:       
1.219     brouard  12299:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12300:     }
                   12301:     fclose(ficreseij);
1.208     brouard  12302:     printf("done evsij\n");fflush(stdout);
                   12303:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12304: 
1.218     brouard  12305:                
1.227     brouard  12306:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12307:                
1.201     brouard  12308:     strcpy(filerest,"T_");
                   12309:     strcat(filerest,fileresu);
1.127     brouard  12310:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12311:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12312:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12313:     }
1.208     brouard  12314:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12315:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12316:     strcpy(fileresstde,"STDE_");
                   12317:     strcat(fileresstde,fileresu);
1.126     brouard  12318:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12319:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12320:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12321:     }
1.227     brouard  12322:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12323:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12324: 
1.201     brouard  12325:     strcpy(filerescve,"CVE_");
                   12326:     strcat(filerescve,fileresu);
1.126     brouard  12327:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12328:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12329:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12330:     }
1.227     brouard  12331:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12332:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12333: 
1.201     brouard  12334:     strcpy(fileresv,"V_");
                   12335:     strcat(fileresv,fileresu);
1.126     brouard  12336:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12337:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12338:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12339:     }
1.227     brouard  12340:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12341:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12342: 
1.235     brouard  12343:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12344:     if (cptcovn < 1){i1=1;}
                   12345:     
                   12346:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12347:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12348:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12349:        continue;
1.242     brouard  12350:       printf("\n#****** Result for:");
                   12351:       fprintf(ficrest,"\n#****** Result for:");
                   12352:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12353:       for(j=1;j<=cptcoveff;j++){ 
                   12354:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12355:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12356:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12357:       }
1.235     brouard  12358:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12359:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12360:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12361:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12362:       }        
1.208     brouard  12363:       fprintf(ficrest,"******\n");
1.227     brouard  12364:       fprintf(ficlog,"******\n");
                   12365:       printf("******\n");
1.208     brouard  12366:       
                   12367:       fprintf(ficresstdeij,"\n#****** ");
                   12368:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12369:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12370:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12371:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12372:       }
1.235     brouard  12373:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12374:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12375:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12376:       }        
1.208     brouard  12377:       fprintf(ficresstdeij,"******\n");
                   12378:       fprintf(ficrescveij,"******\n");
                   12379:       
                   12380:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12381:       /* pstamp(ficresvij); */
1.225     brouard  12382:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12383:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12384:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12385:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12386:       }        
1.208     brouard  12387:       fprintf(ficresvij,"******\n");
                   12388:       
                   12389:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12390:       oldm=oldms;savm=savms;
1.235     brouard  12391:       printf(" cvevsij ");
                   12392:       fprintf(ficlog, " cvevsij ");
                   12393:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12394:       printf(" end cvevsij \n ");
                   12395:       fprintf(ficlog, " end cvevsij \n ");
                   12396:       
                   12397:       /*
                   12398:        */
                   12399:       /* goto endfree; */
                   12400:       
                   12401:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12402:       pstamp(ficrest);
                   12403:       
1.269     brouard  12404:       epj=vector(1,nlstate+1);
1.208     brouard  12405:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12406:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12407:        cptcod= 0; /* To be deleted */
                   12408:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12409:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12410:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12411:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12412:        if(vpopbased==1)
                   12413:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12414:        else
                   12415:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12416:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12417:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12418:        fprintf(ficrest,"\n");
                   12419:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12420:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12421:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12422:        for(age=bage; age <=fage ;age++){
1.235     brouard  12423:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12424:          if (vpopbased==1) {
                   12425:            if(mobilav ==0){
                   12426:              for(i=1; i<=nlstate;i++)
                   12427:                prlim[i][i]=probs[(int)age][i][k];
                   12428:            }else{ /* mobilav */ 
                   12429:              for(i=1; i<=nlstate;i++)
                   12430:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12431:            }
                   12432:          }
1.219     brouard  12433:          
1.227     brouard  12434:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12435:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12436:          /* printf(" age %4.0f ",age); */
                   12437:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12438:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12439:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12440:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12441:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12442:            }
                   12443:            epj[nlstate+1] +=epj[j];
                   12444:          }
                   12445:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12446:          
1.227     brouard  12447:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12448:            for(j=1;j <=nlstate;j++)
                   12449:              vepp += vareij[i][j][(int)age];
                   12450:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12451:          for(j=1;j <=nlstate;j++){
                   12452:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12453:          }
                   12454:          fprintf(ficrest,"\n");
                   12455:        }
1.208     brouard  12456:       } /* End vpopbased */
1.269     brouard  12457:       free_vector(epj,1,nlstate+1);
1.208     brouard  12458:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12459:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12460:       printf("done selection\n");fflush(stdout);
                   12461:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12462:       
1.235     brouard  12463:     } /* End k selection */
1.227     brouard  12464: 
                   12465:     printf("done State-specific expectancies\n");fflush(stdout);
                   12466:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12467: 
1.269     brouard  12468:     /* variance-covariance of period prevalence*/
                   12469:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12470: 
1.227     brouard  12471:     
                   12472:     free_vector(weight,1,n);
                   12473:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12474:     free_imatrix(s,1,maxwav+1,1,n);
                   12475:     free_matrix(anint,1,maxwav,1,n); 
                   12476:     free_matrix(mint,1,maxwav,1,n);
                   12477:     free_ivector(cod,1,n);
                   12478:     free_ivector(tab,1,NCOVMAX);
                   12479:     fclose(ficresstdeij);
                   12480:     fclose(ficrescveij);
                   12481:     fclose(ficresvij);
                   12482:     fclose(ficrest);
                   12483:     fclose(ficpar);
                   12484:     
                   12485:     
1.126     brouard  12486:     /*---------- End : free ----------------*/
1.219     brouard  12487:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12488:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12489:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12490:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12491:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12492:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12493:   /* endfree:*/
                   12494:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12495:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12496:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12497:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12498:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12499:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12500:   free_matrix(covar,0,NCOVMAX,1,n);
                   12501:   free_matrix(matcov,1,npar,1,npar);
                   12502:   free_matrix(hess,1,npar,1,npar);
                   12503:   /*free_vector(delti,1,npar);*/
                   12504:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12505:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12506:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12507:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12508:   
                   12509:   free_ivector(ncodemax,1,NCOVMAX);
                   12510:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12511:   free_ivector(Dummy,-1,NCOVMAX);
                   12512:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12513:   free_ivector(DummyV,1,NCOVMAX);
                   12514:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12515:   free_ivector(Typevar,-1,NCOVMAX);
                   12516:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12517:   free_ivector(TvarsQ,1,NCOVMAX);
                   12518:   free_ivector(TvarsQind,1,NCOVMAX);
                   12519:   free_ivector(TvarsD,1,NCOVMAX);
                   12520:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12521:   free_ivector(TvarFD,1,NCOVMAX);
                   12522:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12523:   free_ivector(TvarF,1,NCOVMAX);
                   12524:   free_ivector(TvarFind,1,NCOVMAX);
                   12525:   free_ivector(TvarV,1,NCOVMAX);
                   12526:   free_ivector(TvarVind,1,NCOVMAX);
                   12527:   free_ivector(TvarA,1,NCOVMAX);
                   12528:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12529:   free_ivector(TvarFQ,1,NCOVMAX);
                   12530:   free_ivector(TvarFQind,1,NCOVMAX);
                   12531:   free_ivector(TvarVD,1,NCOVMAX);
                   12532:   free_ivector(TvarVDind,1,NCOVMAX);
                   12533:   free_ivector(TvarVQ,1,NCOVMAX);
                   12534:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12535:   free_ivector(Tvarsel,1,NCOVMAX);
                   12536:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12537:   free_ivector(Tposprod,1,NCOVMAX);
                   12538:   free_ivector(Tprod,1,NCOVMAX);
                   12539:   free_ivector(Tvaraff,1,NCOVMAX);
                   12540:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12541:   free_ivector(Tage,1,NCOVMAX);
                   12542:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12543:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12544:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12545:   
                   12546:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12547:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12548:   fflush(fichtm);
                   12549:   fflush(ficgp);
                   12550:   
1.227     brouard  12551:   
1.126     brouard  12552:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12553:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12554:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12555:   }else{
                   12556:     printf("End of Imach\n");
                   12557:     fprintf(ficlog,"End of Imach\n");
                   12558:   }
                   12559:   printf("See log file on %s\n",filelog);
                   12560:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12561:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12562:   rend_time = time(NULL);  
                   12563:   end_time = *localtime(&rend_time);
                   12564:   /* tml = *localtime(&end_time.tm_sec); */
                   12565:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12566:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12567:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12568:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12569:   
1.157     brouard  12570:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12571:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12572:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12573:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12574: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12575:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12576:   fclose(fichtm);
                   12577:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12578:   fclose(fichtmcov);
                   12579:   fclose(ficgp);
                   12580:   fclose(ficlog);
                   12581:   /*------ End -----------*/
1.227     brouard  12582:   
                   12583:   
                   12584:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12585: #ifdef WIN32
1.227     brouard  12586:   if (_chdir(pathcd) != 0)
                   12587:     printf("Can't move to directory %s!\n",path);
                   12588:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12589: #else
1.227     brouard  12590:     if(chdir(pathcd) != 0)
                   12591:       printf("Can't move to directory %s!\n", path);
                   12592:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12593: #endif 
1.126     brouard  12594:     printf("Current directory %s!\n",pathcd);
                   12595:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12596:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12597: #ifdef _WIN32
1.126     brouard  12598:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12599: #endif
                   12600:   if(!stat(plotcmd,&info)){
1.158     brouard  12601:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12602:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12603:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12604:     }else
                   12605:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12606: #ifdef __unix
1.126     brouard  12607:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12608:     if(!stat(plotcmd,&info)){
1.158     brouard  12609:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12610:     }else
                   12611:       strcpy(pplotcmd,plotcmd);
                   12612: #endif
                   12613:   }else
                   12614:     strcpy(pplotcmd,plotcmd);
                   12615:   
                   12616:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12617:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12618:   
1.126     brouard  12619:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12620:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12621:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12622:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12623:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12624:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12625:   }
1.158     brouard  12626:   printf(" Successful, please wait...");
1.126     brouard  12627:   while (z[0] != 'q') {
                   12628:     /* chdir(path); */
1.154     brouard  12629:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12630:     scanf("%s",z);
                   12631: /*     if (z[0] == 'c') system("./imach"); */
                   12632:     if (z[0] == 'e') {
1.158     brouard  12633: #ifdef __APPLE__
1.152     brouard  12634:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12635: #elif __linux
                   12636:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12637: #else
1.152     brouard  12638:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12639: #endif
                   12640:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12641:       system(pplotcmd);
1.126     brouard  12642:     }
                   12643:     else if (z[0] == 'g') system(plotcmd);
                   12644:     else if (z[0] == 'q') exit(0);
                   12645:   }
1.227     brouard  12646: end:
1.126     brouard  12647:   while (z[0] != 'q') {
1.195     brouard  12648:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12649:     scanf("%s",z);
                   12650:   }
                   12651: }

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