Annotation of imach/src/imach.c, revision 1.275

1.275   ! brouard     1: /* $Id: imach.c,v 1.274 2017/06/29 09:47:08 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.275   ! brouard     4:   Revision 1.274  2017/06/29 09:47:08  brouard
        !             5:   Summary: Version 0.99r14
        !             6: 
1.274     brouard     7:   Revision 1.273  2017/06/27 11:06:02  brouard
                      8:   Summary: More documentation on projections
                      9: 
1.273     brouard    10:   Revision 1.272  2017/06/27 10:22:40  brouard
                     11:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     12: 
1.272     brouard    13:   Revision 1.271  2017/06/27 10:17:50  brouard
                     14:   Summary: Some bug with rint
                     15: 
1.271     brouard    16:   Revision 1.270  2017/05/24 05:45:29  brouard
                     17:   *** empty log message ***
                     18: 
1.270     brouard    19:   Revision 1.269  2017/05/23 08:39:25  brouard
                     20:   Summary: Code into subroutine, cleanings
                     21: 
1.269     brouard    22:   Revision 1.268  2017/05/18 20:09:32  brouard
                     23:   Summary: backprojection and confidence intervals of backprevalence
                     24: 
1.268     brouard    25:   Revision 1.267  2017/05/13 10:25:05  brouard
                     26:   Summary: temporary save for backprojection
                     27: 
1.267     brouard    28:   Revision 1.266  2017/05/13 07:26:12  brouard
                     29:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     30: 
1.266     brouard    31:   Revision 1.265  2017/04/26 16:22:11  brouard
                     32:   Summary: imach 0.99r13 Some bugs fixed
                     33: 
1.265     brouard    34:   Revision 1.264  2017/04/26 06:01:29  brouard
                     35:   Summary: Labels in graphs
                     36: 
1.264     brouard    37:   Revision 1.263  2017/04/24 15:23:15  brouard
                     38:   Summary: to save
                     39: 
1.263     brouard    40:   Revision 1.262  2017/04/18 16:48:12  brouard
                     41:   *** empty log message ***
                     42: 
1.262     brouard    43:   Revision 1.261  2017/04/05 10:14:09  brouard
                     44:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     45: 
1.261     brouard    46:   Revision 1.260  2017/04/04 17:46:59  brouard
                     47:   Summary: Gnuplot indexations fixed (humm)
                     48: 
1.260     brouard    49:   Revision 1.259  2017/04/04 13:01:16  brouard
                     50:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     51: 
1.259     brouard    52:   Revision 1.258  2017/04/03 10:17:47  brouard
                     53:   Summary: Version 0.99r12
                     54: 
                     55:   Some cleanings, conformed with updated documentation.
                     56: 
1.258     brouard    57:   Revision 1.257  2017/03/29 16:53:30  brouard
                     58:   Summary: Temp
                     59: 
1.257     brouard    60:   Revision 1.256  2017/03/27 05:50:23  brouard
                     61:   Summary: Temporary
                     62: 
1.256     brouard    63:   Revision 1.255  2017/03/08 16:02:28  brouard
                     64:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     65: 
1.255     brouard    66:   Revision 1.254  2017/03/08 07:13:00  brouard
                     67:   Summary: Fixing data parameter line
                     68: 
1.254     brouard    69:   Revision 1.253  2016/12/15 11:59:41  brouard
                     70:   Summary: 0.99 in progress
                     71: 
1.253     brouard    72:   Revision 1.252  2016/09/15 21:15:37  brouard
                     73:   *** empty log message ***
                     74: 
1.252     brouard    75:   Revision 1.251  2016/09/15 15:01:13  brouard
                     76:   Summary: not working
                     77: 
1.251     brouard    78:   Revision 1.250  2016/09/08 16:07:27  brouard
                     79:   Summary: continue
                     80: 
1.250     brouard    81:   Revision 1.249  2016/09/07 17:14:18  brouard
                     82:   Summary: Starting values from frequencies
                     83: 
1.249     brouard    84:   Revision 1.248  2016/09/07 14:10:18  brouard
                     85:   *** empty log message ***
                     86: 
1.248     brouard    87:   Revision 1.247  2016/09/02 11:11:21  brouard
                     88:   *** empty log message ***
                     89: 
1.247     brouard    90:   Revision 1.246  2016/09/02 08:49:22  brouard
                     91:   *** empty log message ***
                     92: 
1.246     brouard    93:   Revision 1.245  2016/09/02 07:25:01  brouard
                     94:   *** empty log message ***
                     95: 
1.245     brouard    96:   Revision 1.244  2016/09/02 07:17:34  brouard
                     97:   *** empty log message ***
                     98: 
1.244     brouard    99:   Revision 1.243  2016/09/02 06:45:35  brouard
                    100:   *** empty log message ***
                    101: 
1.243     brouard   102:   Revision 1.242  2016/08/30 15:01:20  brouard
                    103:   Summary: Fixing a lots
                    104: 
1.242     brouard   105:   Revision 1.241  2016/08/29 17:17:25  brouard
                    106:   Summary: gnuplot problem in Back projection to fix
                    107: 
1.241     brouard   108:   Revision 1.240  2016/08/29 07:53:18  brouard
                    109:   Summary: Better
                    110: 
1.240     brouard   111:   Revision 1.239  2016/08/26 15:51:03  brouard
                    112:   Summary: Improvement in Powell output in order to copy and paste
                    113: 
                    114:   Author:
                    115: 
1.239     brouard   116:   Revision 1.238  2016/08/26 14:23:35  brouard
                    117:   Summary: Starting tests of 0.99
                    118: 
1.238     brouard   119:   Revision 1.237  2016/08/26 09:20:19  brouard
                    120:   Summary: to valgrind
                    121: 
1.237     brouard   122:   Revision 1.236  2016/08/25 10:50:18  brouard
                    123:   *** empty log message ***
                    124: 
1.236     brouard   125:   Revision 1.235  2016/08/25 06:59:23  brouard
                    126:   *** empty log message ***
                    127: 
1.235     brouard   128:   Revision 1.234  2016/08/23 16:51:20  brouard
                    129:   *** empty log message ***
                    130: 
1.234     brouard   131:   Revision 1.233  2016/08/23 07:40:50  brouard
                    132:   Summary: not working
                    133: 
1.233     brouard   134:   Revision 1.232  2016/08/22 14:20:21  brouard
                    135:   Summary: not working
                    136: 
1.232     brouard   137:   Revision 1.231  2016/08/22 07:17:15  brouard
                    138:   Summary: not working
                    139: 
1.231     brouard   140:   Revision 1.230  2016/08/22 06:55:53  brouard
                    141:   Summary: Not working
                    142: 
1.230     brouard   143:   Revision 1.229  2016/07/23 09:45:53  brouard
                    144:   Summary: Completing for func too
                    145: 
1.229     brouard   146:   Revision 1.228  2016/07/22 17:45:30  brouard
                    147:   Summary: Fixing some arrays, still debugging
                    148: 
1.227     brouard   149:   Revision 1.226  2016/07/12 18:42:34  brouard
                    150:   Summary: temp
                    151: 
1.226     brouard   152:   Revision 1.225  2016/07/12 08:40:03  brouard
                    153:   Summary: saving but not running
                    154: 
1.225     brouard   155:   Revision 1.224  2016/07/01 13:16:01  brouard
                    156:   Summary: Fixes
                    157: 
1.224     brouard   158:   Revision 1.223  2016/02/19 09:23:35  brouard
                    159:   Summary: temporary
                    160: 
1.223     brouard   161:   Revision 1.222  2016/02/17 08:14:50  brouard
                    162:   Summary: Probably last 0.98 stable version 0.98r6
                    163: 
1.222     brouard   164:   Revision 1.221  2016/02/15 23:35:36  brouard
                    165:   Summary: minor bug
                    166: 
1.220     brouard   167:   Revision 1.219  2016/02/15 00:48:12  brouard
                    168:   *** empty log message ***
                    169: 
1.219     brouard   170:   Revision 1.218  2016/02/12 11:29:23  brouard
                    171:   Summary: 0.99 Back projections
                    172: 
1.218     brouard   173:   Revision 1.217  2015/12/23 17:18:31  brouard
                    174:   Summary: Experimental backcast
                    175: 
1.217     brouard   176:   Revision 1.216  2015/12/18 17:32:11  brouard
                    177:   Summary: 0.98r4 Warning and status=-2
                    178: 
                    179:   Version 0.98r4 is now:
                    180:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    181:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    182:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    183: 
1.216     brouard   184:   Revision 1.215  2015/12/16 08:52:24  brouard
                    185:   Summary: 0.98r4 working
                    186: 
1.215     brouard   187:   Revision 1.214  2015/12/16 06:57:54  brouard
                    188:   Summary: temporary not working
                    189: 
1.214     brouard   190:   Revision 1.213  2015/12/11 18:22:17  brouard
                    191:   Summary: 0.98r4
                    192: 
1.213     brouard   193:   Revision 1.212  2015/11/21 12:47:24  brouard
                    194:   Summary: minor typo
                    195: 
1.212     brouard   196:   Revision 1.211  2015/11/21 12:41:11  brouard
                    197:   Summary: 0.98r3 with some graph of projected cross-sectional
                    198: 
                    199:   Author: Nicolas Brouard
                    200: 
1.211     brouard   201:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   202:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   203:   Summary: Adding ftolpl parameter
                    204:   Author: N Brouard
                    205: 
                    206:   We had difficulties to get smoothed confidence intervals. It was due
                    207:   to the period prevalence which wasn't computed accurately. The inner
                    208:   parameter ftolpl is now an outer parameter of the .imach parameter
                    209:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    210:   computation are long.
                    211: 
1.209     brouard   212:   Revision 1.208  2015/11/17 14:31:57  brouard
                    213:   Summary: temporary
                    214: 
1.208     brouard   215:   Revision 1.207  2015/10/27 17:36:57  brouard
                    216:   *** empty log message ***
                    217: 
1.207     brouard   218:   Revision 1.206  2015/10/24 07:14:11  brouard
                    219:   *** empty log message ***
                    220: 
1.206     brouard   221:   Revision 1.205  2015/10/23 15:50:53  brouard
                    222:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    223: 
1.205     brouard   224:   Revision 1.204  2015/10/01 16:20:26  brouard
                    225:   Summary: Some new graphs of contribution to likelihood
                    226: 
1.204     brouard   227:   Revision 1.203  2015/09/30 17:45:14  brouard
                    228:   Summary: looking at better estimation of the hessian
                    229: 
                    230:   Also a better criteria for convergence to the period prevalence And
                    231:   therefore adding the number of years needed to converge. (The
                    232:   prevalence in any alive state shold sum to one
                    233: 
1.203     brouard   234:   Revision 1.202  2015/09/22 19:45:16  brouard
                    235:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    236: 
1.202     brouard   237:   Revision 1.201  2015/09/15 17:34:58  brouard
                    238:   Summary: 0.98r0
                    239: 
                    240:   - Some new graphs like suvival functions
                    241:   - Some bugs fixed like model=1+age+V2.
                    242: 
1.201     brouard   243:   Revision 1.200  2015/09/09 16:53:55  brouard
                    244:   Summary: Big bug thanks to Flavia
                    245: 
                    246:   Even model=1+age+V2. did not work anymore
                    247: 
1.200     brouard   248:   Revision 1.199  2015/09/07 14:09:23  brouard
                    249:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    250: 
1.199     brouard   251:   Revision 1.198  2015/09/03 07:14:39  brouard
                    252:   Summary: 0.98q5 Flavia
                    253: 
1.198     brouard   254:   Revision 1.197  2015/09/01 18:24:39  brouard
                    255:   *** empty log message ***
                    256: 
1.197     brouard   257:   Revision 1.196  2015/08/18 23:17:52  brouard
                    258:   Summary: 0.98q5
                    259: 
1.196     brouard   260:   Revision 1.195  2015/08/18 16:28:39  brouard
                    261:   Summary: Adding a hack for testing purpose
                    262: 
                    263:   After reading the title, ftol and model lines, if the comment line has
                    264:   a q, starting with #q, the answer at the end of the run is quit. It
                    265:   permits to run test files in batch with ctest. The former workaround was
                    266:   $ echo q | imach foo.imach
                    267: 
1.195     brouard   268:   Revision 1.194  2015/08/18 13:32:00  brouard
                    269:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    270: 
1.194     brouard   271:   Revision 1.193  2015/08/04 07:17:42  brouard
                    272:   Summary: 0.98q4
                    273: 
1.193     brouard   274:   Revision 1.192  2015/07/16 16:49:02  brouard
                    275:   Summary: Fixing some outputs
                    276: 
1.192     brouard   277:   Revision 1.191  2015/07/14 10:00:33  brouard
                    278:   Summary: Some fixes
                    279: 
1.191     brouard   280:   Revision 1.190  2015/05/05 08:51:13  brouard
                    281:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    282: 
                    283:   Fix 1+age+.
                    284: 
1.190     brouard   285:   Revision 1.189  2015/04/30 14:45:16  brouard
                    286:   Summary: 0.98q2
                    287: 
1.189     brouard   288:   Revision 1.188  2015/04/30 08:27:53  brouard
                    289:   *** empty log message ***
                    290: 
1.188     brouard   291:   Revision 1.187  2015/04/29 09:11:15  brouard
                    292:   *** empty log message ***
                    293: 
1.187     brouard   294:   Revision 1.186  2015/04/23 12:01:52  brouard
                    295:   Summary: V1*age is working now, version 0.98q1
                    296: 
                    297:   Some codes had been disabled in order to simplify and Vn*age was
                    298:   working in the optimization phase, ie, giving correct MLE parameters,
                    299:   but, as usual, outputs were not correct and program core dumped.
                    300: 
1.186     brouard   301:   Revision 1.185  2015/03/11 13:26:42  brouard
                    302:   Summary: Inclusion of compile and links command line for Intel Compiler
                    303: 
1.185     brouard   304:   Revision 1.184  2015/03/11 11:52:39  brouard
                    305:   Summary: Back from Windows 8. Intel Compiler
                    306: 
1.184     brouard   307:   Revision 1.183  2015/03/10 20:34:32  brouard
                    308:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    309: 
                    310:   We use directest instead of original Powell test; probably no
                    311:   incidence on the results, but better justifications;
                    312:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    313:   wrong results.
                    314: 
1.183     brouard   315:   Revision 1.182  2015/02/12 08:19:57  brouard
                    316:   Summary: Trying to keep directest which seems simpler and more general
                    317:   Author: Nicolas Brouard
                    318: 
1.182     brouard   319:   Revision 1.181  2015/02/11 23:22:24  brouard
                    320:   Summary: Comments on Powell added
                    321: 
                    322:   Author:
                    323: 
1.181     brouard   324:   Revision 1.180  2015/02/11 17:33:45  brouard
                    325:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    326: 
1.180     brouard   327:   Revision 1.179  2015/01/04 09:57:06  brouard
                    328:   Summary: back to OS/X
                    329: 
1.179     brouard   330:   Revision 1.178  2015/01/04 09:35:48  brouard
                    331:   *** empty log message ***
                    332: 
1.178     brouard   333:   Revision 1.177  2015/01/03 18:40:56  brouard
                    334:   Summary: Still testing ilc32 on OSX
                    335: 
1.177     brouard   336:   Revision 1.176  2015/01/03 16:45:04  brouard
                    337:   *** empty log message ***
                    338: 
1.176     brouard   339:   Revision 1.175  2015/01/03 16:33:42  brouard
                    340:   *** empty log message ***
                    341: 
1.175     brouard   342:   Revision 1.174  2015/01/03 16:15:49  brouard
                    343:   Summary: Still in cross-compilation
                    344: 
1.174     brouard   345:   Revision 1.173  2015/01/03 12:06:26  brouard
                    346:   Summary: trying to detect cross-compilation
                    347: 
1.173     brouard   348:   Revision 1.172  2014/12/27 12:07:47  brouard
                    349:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    350: 
1.172     brouard   351:   Revision 1.171  2014/12/23 13:26:59  brouard
                    352:   Summary: Back from Visual C
                    353: 
                    354:   Still problem with utsname.h on Windows
                    355: 
1.171     brouard   356:   Revision 1.170  2014/12/23 11:17:12  brouard
                    357:   Summary: Cleaning some \%% back to %%
                    358: 
                    359:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    360: 
1.170     brouard   361:   Revision 1.169  2014/12/22 23:08:31  brouard
                    362:   Summary: 0.98p
                    363: 
                    364:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    365: 
1.169     brouard   366:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   367:   Summary: update
1.169     brouard   368: 
1.168     brouard   369:   Revision 1.167  2014/12/22 13:50:56  brouard
                    370:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    371: 
                    372:   Testing on Linux 64
                    373: 
1.167     brouard   374:   Revision 1.166  2014/12/22 11:40:47  brouard
                    375:   *** empty log message ***
                    376: 
1.166     brouard   377:   Revision 1.165  2014/12/16 11:20:36  brouard
                    378:   Summary: After compiling on Visual C
                    379: 
                    380:   * imach.c (Module): Merging 1.61 to 1.162
                    381: 
1.165     brouard   382:   Revision 1.164  2014/12/16 10:52:11  brouard
                    383:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    384: 
                    385:   * imach.c (Module): Merging 1.61 to 1.162
                    386: 
1.164     brouard   387:   Revision 1.163  2014/12/16 10:30:11  brouard
                    388:   * imach.c (Module): Merging 1.61 to 1.162
                    389: 
1.163     brouard   390:   Revision 1.162  2014/09/25 11:43:39  brouard
                    391:   Summary: temporary backup 0.99!
                    392: 
1.162     brouard   393:   Revision 1.1  2014/09/16 11:06:58  brouard
                    394:   Summary: With some code (wrong) for nlopt
                    395: 
                    396:   Author:
                    397: 
                    398:   Revision 1.161  2014/09/15 20:41:41  brouard
                    399:   Summary: Problem with macro SQR on Intel compiler
                    400: 
1.161     brouard   401:   Revision 1.160  2014/09/02 09:24:05  brouard
                    402:   *** empty log message ***
                    403: 
1.160     brouard   404:   Revision 1.159  2014/09/01 10:34:10  brouard
                    405:   Summary: WIN32
                    406:   Author: Brouard
                    407: 
1.159     brouard   408:   Revision 1.158  2014/08/27 17:11:51  brouard
                    409:   *** empty log message ***
                    410: 
1.158     brouard   411:   Revision 1.157  2014/08/27 16:26:55  brouard
                    412:   Summary: Preparing windows Visual studio version
                    413:   Author: Brouard
                    414: 
                    415:   In order to compile on Visual studio, time.h is now correct and time_t
                    416:   and tm struct should be used. difftime should be used but sometimes I
                    417:   just make the differences in raw time format (time(&now).
                    418:   Trying to suppress #ifdef LINUX
                    419:   Add xdg-open for __linux in order to open default browser.
                    420: 
1.157     brouard   421:   Revision 1.156  2014/08/25 20:10:10  brouard
                    422:   *** empty log message ***
                    423: 
1.156     brouard   424:   Revision 1.155  2014/08/25 18:32:34  brouard
                    425:   Summary: New compile, minor changes
                    426:   Author: Brouard
                    427: 
1.155     brouard   428:   Revision 1.154  2014/06/20 17:32:08  brouard
                    429:   Summary: Outputs now all graphs of convergence to period prevalence
                    430: 
1.154     brouard   431:   Revision 1.153  2014/06/20 16:45:46  brouard
                    432:   Summary: If 3 live state, convergence to period prevalence on same graph
                    433:   Author: Brouard
                    434: 
1.153     brouard   435:   Revision 1.152  2014/06/18 17:54:09  brouard
                    436:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    437: 
1.152     brouard   438:   Revision 1.151  2014/06/18 16:43:30  brouard
                    439:   *** empty log message ***
                    440: 
1.151     brouard   441:   Revision 1.150  2014/06/18 16:42:35  brouard
                    442:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    443:   Author: brouard
                    444: 
1.150     brouard   445:   Revision 1.149  2014/06/18 15:51:14  brouard
                    446:   Summary: Some fixes in parameter files errors
                    447:   Author: Nicolas Brouard
                    448: 
1.149     brouard   449:   Revision 1.148  2014/06/17 17:38:48  brouard
                    450:   Summary: Nothing new
                    451:   Author: Brouard
                    452: 
                    453:   Just a new packaging for OS/X version 0.98nS
                    454: 
1.148     brouard   455:   Revision 1.147  2014/06/16 10:33:11  brouard
                    456:   *** empty log message ***
                    457: 
1.147     brouard   458:   Revision 1.146  2014/06/16 10:20:28  brouard
                    459:   Summary: Merge
                    460:   Author: Brouard
                    461: 
                    462:   Merge, before building revised version.
                    463: 
1.146     brouard   464:   Revision 1.145  2014/06/10 21:23:15  brouard
                    465:   Summary: Debugging with valgrind
                    466:   Author: Nicolas Brouard
                    467: 
                    468:   Lot of changes in order to output the results with some covariates
                    469:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    470:   improve the code.
                    471:   No more memory valgrind error but a lot has to be done in order to
                    472:   continue the work of splitting the code into subroutines.
                    473:   Also, decodemodel has been improved. Tricode is still not
                    474:   optimal. nbcode should be improved. Documentation has been added in
                    475:   the source code.
                    476: 
1.144     brouard   477:   Revision 1.143  2014/01/26 09:45:38  brouard
                    478:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    479: 
                    480:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    481:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    482: 
1.143     brouard   483:   Revision 1.142  2014/01/26 03:57:36  brouard
                    484:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    485: 
                    486:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    487: 
1.142     brouard   488:   Revision 1.141  2014/01/26 02:42:01  brouard
                    489:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    490: 
1.141     brouard   491:   Revision 1.140  2011/09/02 10:37:54  brouard
                    492:   Summary: times.h is ok with mingw32 now.
                    493: 
1.140     brouard   494:   Revision 1.139  2010/06/14 07:50:17  brouard
                    495:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    496:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    497: 
1.139     brouard   498:   Revision 1.138  2010/04/30 18:19:40  brouard
                    499:   *** empty log message ***
                    500: 
1.138     brouard   501:   Revision 1.137  2010/04/29 18:11:38  brouard
                    502:   (Module): Checking covariates for more complex models
                    503:   than V1+V2. A lot of change to be done. Unstable.
                    504: 
1.137     brouard   505:   Revision 1.136  2010/04/26 20:30:53  brouard
                    506:   (Module): merging some libgsl code. Fixing computation
                    507:   of likelione (using inter/intrapolation if mle = 0) in order to
                    508:   get same likelihood as if mle=1.
                    509:   Some cleaning of code and comments added.
                    510: 
1.136     brouard   511:   Revision 1.135  2009/10/29 15:33:14  brouard
                    512:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    513: 
1.135     brouard   514:   Revision 1.134  2009/10/29 13:18:53  brouard
                    515:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    516: 
1.134     brouard   517:   Revision 1.133  2009/07/06 10:21:25  brouard
                    518:   just nforces
                    519: 
1.133     brouard   520:   Revision 1.132  2009/07/06 08:22:05  brouard
                    521:   Many tings
                    522: 
1.132     brouard   523:   Revision 1.131  2009/06/20 16:22:47  brouard
                    524:   Some dimensions resccaled
                    525: 
1.131     brouard   526:   Revision 1.130  2009/05/26 06:44:34  brouard
                    527:   (Module): Max Covariate is now set to 20 instead of 8. A
                    528:   lot of cleaning with variables initialized to 0. Trying to make
                    529:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    530: 
1.130     brouard   531:   Revision 1.129  2007/08/31 13:49:27  lievre
                    532:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    533: 
1.129     lievre    534:   Revision 1.128  2006/06/30 13:02:05  brouard
                    535:   (Module): Clarifications on computing e.j
                    536: 
1.128     brouard   537:   Revision 1.127  2006/04/28 18:11:50  brouard
                    538:   (Module): Yes the sum of survivors was wrong since
                    539:   imach-114 because nhstepm was no more computed in the age
                    540:   loop. Now we define nhstepma in the age loop.
                    541:   (Module): In order to speed up (in case of numerous covariates) we
                    542:   compute health expectancies (without variances) in a first step
                    543:   and then all the health expectancies with variances or standard
                    544:   deviation (needs data from the Hessian matrices) which slows the
                    545:   computation.
                    546:   In the future we should be able to stop the program is only health
                    547:   expectancies and graph are needed without standard deviations.
                    548: 
1.127     brouard   549:   Revision 1.126  2006/04/28 17:23:28  brouard
                    550:   (Module): Yes the sum of survivors was wrong since
                    551:   imach-114 because nhstepm was no more computed in the age
                    552:   loop. Now we define nhstepma in the age loop.
                    553:   Version 0.98h
                    554: 
1.126     brouard   555:   Revision 1.125  2006/04/04 15:20:31  lievre
                    556:   Errors in calculation of health expectancies. Age was not initialized.
                    557:   Forecasting file added.
                    558: 
                    559:   Revision 1.124  2006/03/22 17:13:53  lievre
                    560:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    561:   The log-likelihood is printed in the log file
                    562: 
                    563:   Revision 1.123  2006/03/20 10:52:43  brouard
                    564:   * imach.c (Module): <title> changed, corresponds to .htm file
                    565:   name. <head> headers where missing.
                    566: 
                    567:   * imach.c (Module): Weights can have a decimal point as for
                    568:   English (a comma might work with a correct LC_NUMERIC environment,
                    569:   otherwise the weight is truncated).
                    570:   Modification of warning when the covariates values are not 0 or
                    571:   1.
                    572:   Version 0.98g
                    573: 
                    574:   Revision 1.122  2006/03/20 09:45:41  brouard
                    575:   (Module): Weights can have a decimal point as for
                    576:   English (a comma might work with a correct LC_NUMERIC environment,
                    577:   otherwise the weight is truncated).
                    578:   Modification of warning when the covariates values are not 0 or
                    579:   1.
                    580:   Version 0.98g
                    581: 
                    582:   Revision 1.121  2006/03/16 17:45:01  lievre
                    583:   * imach.c (Module): Comments concerning covariates added
                    584: 
                    585:   * imach.c (Module): refinements in the computation of lli if
                    586:   status=-2 in order to have more reliable computation if stepm is
                    587:   not 1 month. Version 0.98f
                    588: 
                    589:   Revision 1.120  2006/03/16 15:10:38  lievre
                    590:   (Module): refinements in the computation of lli if
                    591:   status=-2 in order to have more reliable computation if stepm is
                    592:   not 1 month. Version 0.98f
                    593: 
                    594:   Revision 1.119  2006/03/15 17:42:26  brouard
                    595:   (Module): Bug if status = -2, the loglikelihood was
                    596:   computed as likelihood omitting the logarithm. Version O.98e
                    597: 
                    598:   Revision 1.118  2006/03/14 18:20:07  brouard
                    599:   (Module): varevsij Comments added explaining the second
                    600:   table of variances if popbased=1 .
                    601:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    602:   (Module): Function pstamp added
                    603:   (Module): Version 0.98d
                    604: 
                    605:   Revision 1.117  2006/03/14 17:16:22  brouard
                    606:   (Module): varevsij Comments added explaining the second
                    607:   table of variances if popbased=1 .
                    608:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    609:   (Module): Function pstamp added
                    610:   (Module): Version 0.98d
                    611: 
                    612:   Revision 1.116  2006/03/06 10:29:27  brouard
                    613:   (Module): Variance-covariance wrong links and
                    614:   varian-covariance of ej. is needed (Saito).
                    615: 
                    616:   Revision 1.115  2006/02/27 12:17:45  brouard
                    617:   (Module): One freematrix added in mlikeli! 0.98c
                    618: 
                    619:   Revision 1.114  2006/02/26 12:57:58  brouard
                    620:   (Module): Some improvements in processing parameter
                    621:   filename with strsep.
                    622: 
                    623:   Revision 1.113  2006/02/24 14:20:24  brouard
                    624:   (Module): Memory leaks checks with valgrind and:
                    625:   datafile was not closed, some imatrix were not freed and on matrix
                    626:   allocation too.
                    627: 
                    628:   Revision 1.112  2006/01/30 09:55:26  brouard
                    629:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    630: 
                    631:   Revision 1.111  2006/01/25 20:38:18  brouard
                    632:   (Module): Lots of cleaning and bugs added (Gompertz)
                    633:   (Module): Comments can be added in data file. Missing date values
                    634:   can be a simple dot '.'.
                    635: 
                    636:   Revision 1.110  2006/01/25 00:51:50  brouard
                    637:   (Module): Lots of cleaning and bugs added (Gompertz)
                    638: 
                    639:   Revision 1.109  2006/01/24 19:37:15  brouard
                    640:   (Module): Comments (lines starting with a #) are allowed in data.
                    641: 
                    642:   Revision 1.108  2006/01/19 18:05:42  lievre
                    643:   Gnuplot problem appeared...
                    644:   To be fixed
                    645: 
                    646:   Revision 1.107  2006/01/19 16:20:37  brouard
                    647:   Test existence of gnuplot in imach path
                    648: 
                    649:   Revision 1.106  2006/01/19 13:24:36  brouard
                    650:   Some cleaning and links added in html output
                    651: 
                    652:   Revision 1.105  2006/01/05 20:23:19  lievre
                    653:   *** empty log message ***
                    654: 
                    655:   Revision 1.104  2005/09/30 16:11:43  lievre
                    656:   (Module): sump fixed, loop imx fixed, and simplifications.
                    657:   (Module): If the status is missing at the last wave but we know
                    658:   that the person is alive, then we can code his/her status as -2
                    659:   (instead of missing=-1 in earlier versions) and his/her
                    660:   contributions to the likelihood is 1 - Prob of dying from last
                    661:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    662:   the healthy state at last known wave). Version is 0.98
                    663: 
                    664:   Revision 1.103  2005/09/30 15:54:49  lievre
                    665:   (Module): sump fixed, loop imx fixed, and simplifications.
                    666: 
                    667:   Revision 1.102  2004/09/15 17:31:30  brouard
                    668:   Add the possibility to read data file including tab characters.
                    669: 
                    670:   Revision 1.101  2004/09/15 10:38:38  brouard
                    671:   Fix on curr_time
                    672: 
                    673:   Revision 1.100  2004/07/12 18:29:06  brouard
                    674:   Add version for Mac OS X. Just define UNIX in Makefile
                    675: 
                    676:   Revision 1.99  2004/06/05 08:57:40  brouard
                    677:   *** empty log message ***
                    678: 
                    679:   Revision 1.98  2004/05/16 15:05:56  brouard
                    680:   New version 0.97 . First attempt to estimate force of mortality
                    681:   directly from the data i.e. without the need of knowing the health
                    682:   state at each age, but using a Gompertz model: log u =a + b*age .
                    683:   This is the basic analysis of mortality and should be done before any
                    684:   other analysis, in order to test if the mortality estimated from the
                    685:   cross-longitudinal survey is different from the mortality estimated
                    686:   from other sources like vital statistic data.
                    687: 
                    688:   The same imach parameter file can be used but the option for mle should be -3.
                    689: 
1.133     brouard   690:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   691:   former routines in order to include the new code within the former code.
                    692: 
                    693:   The output is very simple: only an estimate of the intercept and of
                    694:   the slope with 95% confident intervals.
                    695: 
                    696:   Current limitations:
                    697:   A) Even if you enter covariates, i.e. with the
                    698:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    699:   B) There is no computation of Life Expectancy nor Life Table.
                    700: 
                    701:   Revision 1.97  2004/02/20 13:25:42  lievre
                    702:   Version 0.96d. Population forecasting command line is (temporarily)
                    703:   suppressed.
                    704: 
                    705:   Revision 1.96  2003/07/15 15:38:55  brouard
                    706:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    707:   rewritten within the same printf. Workaround: many printfs.
                    708: 
                    709:   Revision 1.95  2003/07/08 07:54:34  brouard
                    710:   * imach.c (Repository):
                    711:   (Repository): Using imachwizard code to output a more meaningful covariance
                    712:   matrix (cov(a12,c31) instead of numbers.
                    713: 
                    714:   Revision 1.94  2003/06/27 13:00:02  brouard
                    715:   Just cleaning
                    716: 
                    717:   Revision 1.93  2003/06/25 16:33:55  brouard
                    718:   (Module): On windows (cygwin) function asctime_r doesn't
                    719:   exist so I changed back to asctime which exists.
                    720:   (Module): Version 0.96b
                    721: 
                    722:   Revision 1.92  2003/06/25 16:30:45  brouard
                    723:   (Module): On windows (cygwin) function asctime_r doesn't
                    724:   exist so I changed back to asctime which exists.
                    725: 
                    726:   Revision 1.91  2003/06/25 15:30:29  brouard
                    727:   * imach.c (Repository): Duplicated warning errors corrected.
                    728:   (Repository): Elapsed time after each iteration is now output. It
                    729:   helps to forecast when convergence will be reached. Elapsed time
                    730:   is stamped in powell.  We created a new html file for the graphs
                    731:   concerning matrix of covariance. It has extension -cov.htm.
                    732: 
                    733:   Revision 1.90  2003/06/24 12:34:15  brouard
                    734:   (Module): Some bugs corrected for windows. Also, when
                    735:   mle=-1 a template is output in file "or"mypar.txt with the design
                    736:   of the covariance matrix to be input.
                    737: 
                    738:   Revision 1.89  2003/06/24 12:30:52  brouard
                    739:   (Module): Some bugs corrected for windows. Also, when
                    740:   mle=-1 a template is output in file "or"mypar.txt with the design
                    741:   of the covariance matrix to be input.
                    742: 
                    743:   Revision 1.88  2003/06/23 17:54:56  brouard
                    744:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    745: 
                    746:   Revision 1.87  2003/06/18 12:26:01  brouard
                    747:   Version 0.96
                    748: 
                    749:   Revision 1.86  2003/06/17 20:04:08  brouard
                    750:   (Module): Change position of html and gnuplot routines and added
                    751:   routine fileappend.
                    752: 
                    753:   Revision 1.85  2003/06/17 13:12:43  brouard
                    754:   * imach.c (Repository): Check when date of death was earlier that
                    755:   current date of interview. It may happen when the death was just
                    756:   prior to the death. In this case, dh was negative and likelihood
                    757:   was wrong (infinity). We still send an "Error" but patch by
                    758:   assuming that the date of death was just one stepm after the
                    759:   interview.
                    760:   (Repository): Because some people have very long ID (first column)
                    761:   we changed int to long in num[] and we added a new lvector for
                    762:   memory allocation. But we also truncated to 8 characters (left
                    763:   truncation)
                    764:   (Repository): No more line truncation errors.
                    765: 
                    766:   Revision 1.84  2003/06/13 21:44:43  brouard
                    767:   * imach.c (Repository): Replace "freqsummary" at a correct
                    768:   place. It differs from routine "prevalence" which may be called
                    769:   many times. Probs is memory consuming and must be used with
                    770:   parcimony.
                    771:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    772: 
                    773:   Revision 1.83  2003/06/10 13:39:11  lievre
                    774:   *** empty log message ***
                    775: 
                    776:   Revision 1.82  2003/06/05 15:57:20  brouard
                    777:   Add log in  imach.c and  fullversion number is now printed.
                    778: 
                    779: */
                    780: /*
                    781:    Interpolated Markov Chain
                    782: 
                    783:   Short summary of the programme:
                    784:   
1.227     brouard   785:   This program computes Healthy Life Expectancies or State-specific
                    786:   (if states aren't health statuses) Expectancies from
                    787:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    788: 
                    789:   -1- a first survey ("cross") where individuals from different ages
                    790:   are interviewed on their health status or degree of disability (in
                    791:   the case of a health survey which is our main interest)
                    792: 
                    793:   -2- at least a second wave of interviews ("longitudinal") which
                    794:   measure each change (if any) in individual health status.  Health
                    795:   expectancies are computed from the time spent in each health state
                    796:   according to a model. More health states you consider, more time is
                    797:   necessary to reach the Maximum Likelihood of the parameters involved
                    798:   in the model.  The simplest model is the multinomial logistic model
                    799:   where pij is the probability to be observed in state j at the second
                    800:   wave conditional to be observed in state i at the first
                    801:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    802:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    803:   have a more complex model than "constant and age", you should modify
                    804:   the program where the markup *Covariates have to be included here
                    805:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   806:   convergence.
                    807: 
                    808:   The advantage of this computer programme, compared to a simple
                    809:   multinomial logistic model, is clear when the delay between waves is not
                    810:   identical for each individual. Also, if a individual missed an
                    811:   intermediate interview, the information is lost, but taken into
                    812:   account using an interpolation or extrapolation.  
                    813: 
                    814:   hPijx is the probability to be observed in state i at age x+h
                    815:   conditional to the observed state i at age x. The delay 'h' can be
                    816:   split into an exact number (nh*stepm) of unobserved intermediate
                    817:   states. This elementary transition (by month, quarter,
                    818:   semester or year) is modelled as a multinomial logistic.  The hPx
                    819:   matrix is simply the matrix product of nh*stepm elementary matrices
                    820:   and the contribution of each individual to the likelihood is simply
                    821:   hPijx.
                    822: 
                    823:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   824:   of the life expectancies. It also computes the period (stable) prevalence.
                    825: 
                    826: Back prevalence and projections:
1.227     brouard   827: 
                    828:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    829:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    830:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    831:    mobilavproj)
                    832: 
                    833:     Computes the back prevalence limit for any combination of
                    834:     covariate values k at any age between ageminpar and agemaxpar and
                    835:     returns it in **bprlim. In the loops,
                    836: 
                    837:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    838:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    839: 
                    840:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   841:    Computes for any combination of covariates k and any age between bage and fage 
                    842:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    843:                        oldm=oldms;savm=savms;
1.227     brouard   844: 
1.267     brouard   845:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   846:      Computes the transition matrix starting at age 'age' over
                    847:      'nhstepm*hstepm*stepm' months (i.e. until
                    848:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   849:      nhstepm*hstepm matrices. 
                    850: 
                    851:      Returns p3mat[i][j][h] after calling
                    852:      p3mat[i][j][h]=matprod2(newm,
                    853:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    854:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    855:      oldm);
1.226     brouard   856: 
                    857: Important routines
                    858: 
                    859: - func (or funcone), computes logit (pij) distinguishing
                    860:   o fixed variables (single or product dummies or quantitative);
                    861:   o varying variables by:
                    862:    (1) wave (single, product dummies, quantitative), 
                    863:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    864:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    865:        % varying dummy (not done) or quantitative (not done);
                    866: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    867:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    868: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    869:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    870:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   871: 
1.226     brouard   872: 
                    873:   
1.133     brouard   874:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    875:            Institut national d'études démographiques, Paris.
1.126     brouard   876:   This software have been partly granted by Euro-REVES, a concerted action
                    877:   from the European Union.
                    878:   It is copyrighted identically to a GNU software product, ie programme and
                    879:   software can be distributed freely for non commercial use. Latest version
                    880:   can be accessed at http://euroreves.ined.fr/imach .
                    881: 
                    882:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    883:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    884:   
                    885:   **********************************************************************/
                    886: /*
                    887:   main
                    888:   read parameterfile
                    889:   read datafile
                    890:   concatwav
                    891:   freqsummary
                    892:   if (mle >= 1)
                    893:     mlikeli
                    894:   print results files
                    895:   if mle==1 
                    896:      computes hessian
                    897:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    898:       begin-prev-date,...
                    899:   open gnuplot file
                    900:   open html file
1.145     brouard   901:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    902:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    903:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    904:     freexexit2 possible for memory heap.
                    905: 
                    906:   h Pij x                         | pij_nom  ficrestpij
                    907:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    908:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    909:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    910: 
                    911:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    912:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    913:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    914:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    915:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    916: 
1.126     brouard   917:   forecasting if prevfcast==1 prevforecast call prevalence()
                    918:   health expectancies
                    919:   Variance-covariance of DFLE
                    920:   prevalence()
                    921:    movingaverage()
                    922:   varevsij() 
                    923:   if popbased==1 varevsij(,popbased)
                    924:   total life expectancies
                    925:   Variance of period (stable) prevalence
                    926:  end
                    927: */
                    928: 
1.187     brouard   929: /* #define DEBUG */
                    930: /* #define DEBUGBRENT */
1.203     brouard   931: /* #define DEBUGLINMIN */
                    932: /* #define DEBUGHESS */
                    933: #define DEBUGHESSIJ
1.224     brouard   934: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   935: #define POWELL /* Instead of NLOPT */
1.224     brouard   936: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   937: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    938: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   939: 
                    940: #include <math.h>
                    941: #include <stdio.h>
                    942: #include <stdlib.h>
                    943: #include <string.h>
1.226     brouard   944: #include <ctype.h>
1.159     brouard   945: 
                    946: #ifdef _WIN32
                    947: #include <io.h>
1.172     brouard   948: #include <windows.h>
                    949: #include <tchar.h>
1.159     brouard   950: #else
1.126     brouard   951: #include <unistd.h>
1.159     brouard   952: #endif
1.126     brouard   953: 
                    954: #include <limits.h>
                    955: #include <sys/types.h>
1.171     brouard   956: 
                    957: #if defined(__GNUC__)
                    958: #include <sys/utsname.h> /* Doesn't work on Windows */
                    959: #endif
                    960: 
1.126     brouard   961: #include <sys/stat.h>
                    962: #include <errno.h>
1.159     brouard   963: /* extern int errno; */
1.126     brouard   964: 
1.157     brouard   965: /* #ifdef LINUX */
                    966: /* #include <time.h> */
                    967: /* #include "timeval.h" */
                    968: /* #else */
                    969: /* #include <sys/time.h> */
                    970: /* #endif */
                    971: 
1.126     brouard   972: #include <time.h>
                    973: 
1.136     brouard   974: #ifdef GSL
                    975: #include <gsl/gsl_errno.h>
                    976: #include <gsl/gsl_multimin.h>
                    977: #endif
                    978: 
1.167     brouard   979: 
1.162     brouard   980: #ifdef NLOPT
                    981: #include <nlopt.h>
                    982: typedef struct {
                    983:   double (* function)(double [] );
                    984: } myfunc_data ;
                    985: #endif
                    986: 
1.126     brouard   987: /* #include <libintl.h> */
                    988: /* #define _(String) gettext (String) */
                    989: 
1.251     brouard   990: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   991: 
                    992: #define GNUPLOTPROGRAM "gnuplot"
                    993: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    994: #define FILENAMELENGTH 132
                    995: 
                    996: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    997: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    998: 
1.144     brouard   999: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1000: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1001: 
                   1002: #define NINTERVMAX 8
1.144     brouard  1003: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1004: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1005: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1006: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1007: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1008: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1009: #define MAXN 20000
1.144     brouard  1010: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1011: /* #define AGESUP 130 */
                   1012: #define AGESUP 150
1.268     brouard  1013: #define AGEINF 0
1.218     brouard  1014: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1015: #define AGEBASE 40
1.194     brouard  1016: #define AGEOVERFLOW 1.e20
1.164     brouard  1017: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1018: #ifdef _WIN32
                   1019: #define DIRSEPARATOR '\\'
                   1020: #define CHARSEPARATOR "\\"
                   1021: #define ODIRSEPARATOR '/'
                   1022: #else
1.126     brouard  1023: #define DIRSEPARATOR '/'
                   1024: #define CHARSEPARATOR "/"
                   1025: #define ODIRSEPARATOR '\\'
                   1026: #endif
                   1027: 
1.275   ! brouard  1028: /* $Id: imach.c,v 1.274 2017/06/29 09:47:08 brouard Exp $ */
1.126     brouard  1029: /* $State: Exp $ */
1.196     brouard  1030: #include "version.h"
                   1031: char version[]=__IMACH_VERSION__;
1.224     brouard  1032: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.275   ! brouard  1033: char fullversion[]="$Revision: 1.274 $ $Date: 2017/06/29 09:47:08 $"; 
1.126     brouard  1034: char strstart[80];
                   1035: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1036: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1037: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1038: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1039: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1040: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1041: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1042: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1043: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1044: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1045: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1046: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1047: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1048: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1049: int nsd=0; /**< Total number of single dummy variables (output) */
                   1050: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1051: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1052: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1053: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1054: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1055: int cptcov=0; /* Working variable */
1.218     brouard  1056: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1057: int npar=NPARMAX;
                   1058: int nlstate=2; /* Number of live states */
                   1059: int ndeath=1; /* Number of dead states */
1.130     brouard  1060: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1061: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1062: int popbased=0;
                   1063: 
                   1064: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1065: int maxwav=0; /* Maxim number of waves */
                   1066: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1067: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1068: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1069:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1070: int mle=1, weightopt=0;
1.126     brouard  1071: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1072: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1073: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1074:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1075: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1076: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1077: 
1.130     brouard  1078: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1079: double **matprod2(); /* test */
1.126     brouard  1080: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1081: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1082: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1083: 
1.136     brouard  1084: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1085: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1086: FILE *ficlog, *ficrespow;
1.130     brouard  1087: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1088: double fretone; /* Only one call to likelihood */
1.130     brouard  1089: long ipmx=0; /* Number of contributions */
1.126     brouard  1090: double sw; /* Sum of weights */
                   1091: char filerespow[FILENAMELENGTH];
                   1092: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1093: FILE *ficresilk;
                   1094: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1095: FILE *ficresprobmorprev;
                   1096: FILE *fichtm, *fichtmcov; /* Html File */
                   1097: FILE *ficreseij;
                   1098: char filerese[FILENAMELENGTH];
                   1099: FILE *ficresstdeij;
                   1100: char fileresstde[FILENAMELENGTH];
                   1101: FILE *ficrescveij;
                   1102: char filerescve[FILENAMELENGTH];
                   1103: FILE  *ficresvij;
                   1104: char fileresv[FILENAMELENGTH];
1.269     brouard  1105: 
1.126     brouard  1106: char title[MAXLINE];
1.234     brouard  1107: char model[MAXLINE]; /**< The model line */
1.217     brouard  1108: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1109: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1110: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1111: char command[FILENAMELENGTH];
                   1112: int  outcmd=0;
                   1113: 
1.217     brouard  1114: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1115: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1116: char filelog[FILENAMELENGTH]; /* Log file */
                   1117: char filerest[FILENAMELENGTH];
                   1118: char fileregp[FILENAMELENGTH];
                   1119: char popfile[FILENAMELENGTH];
                   1120: 
                   1121: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1122: 
1.157     brouard  1123: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1124: /* struct timezone tzp; */
                   1125: /* extern int gettimeofday(); */
                   1126: struct tm tml, *gmtime(), *localtime();
                   1127: 
                   1128: extern time_t time();
                   1129: 
                   1130: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1131: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1132: struct tm tm;
                   1133: 
1.126     brouard  1134: char strcurr[80], strfor[80];
                   1135: 
                   1136: char *endptr;
                   1137: long lval;
                   1138: double dval;
                   1139: 
                   1140: #define NR_END 1
                   1141: #define FREE_ARG char*
                   1142: #define FTOL 1.0e-10
                   1143: 
                   1144: #define NRANSI 
1.240     brouard  1145: #define ITMAX 200
                   1146: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1147: 
                   1148: #define TOL 2.0e-4 
                   1149: 
                   1150: #define CGOLD 0.3819660 
                   1151: #define ZEPS 1.0e-10 
                   1152: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1153: 
                   1154: #define GOLD 1.618034 
                   1155: #define GLIMIT 100.0 
                   1156: #define TINY 1.0e-20 
                   1157: 
                   1158: static double maxarg1,maxarg2;
                   1159: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1160: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1161:   
                   1162: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1163: #define rint(a) floor(a+0.5)
1.166     brouard  1164: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1165: #define mytinydouble 1.0e-16
1.166     brouard  1166: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1167: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1168: /* static double dsqrarg; */
                   1169: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1170: static double sqrarg;
                   1171: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1172: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1173: int agegomp= AGEGOMP;
                   1174: 
                   1175: int imx; 
                   1176: int stepm=1;
                   1177: /* Stepm, step in month: minimum step interpolation*/
                   1178: 
                   1179: int estepm;
                   1180: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1181: 
                   1182: int m,nb;
                   1183: long *num;
1.197     brouard  1184: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1185: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1186:                   covariate for which somebody answered excluding 
                   1187:                   undefined. Usually 2: 0 and 1. */
                   1188: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1189:                             covariate for which somebody answered including 
                   1190:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1191: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1192: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1193: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1194: double *ageexmed,*agecens;
                   1195: double dateintmean=0;
                   1196: 
                   1197: double *weight;
                   1198: int **s; /* Status */
1.141     brouard  1199: double *agedc;
1.145     brouard  1200: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1201:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1202:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1203: double **coqvar; /* Fixed quantitative covariate nqv */
                   1204: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1205: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1206: double  idx; 
                   1207: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1208: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1209: /*k          1  2   3   4     5    6    7     8    9 */
                   1210: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1211: /* Tndvar[k]    1   2   3               4          5 */
                   1212: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1213: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1214: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1215: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1216: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1217: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1218: /* Tprod[i]=k           4               7            */
                   1219: /* Tage[i]=k                  5               8      */
                   1220: /* */
                   1221: /* Type                    */
                   1222: /* V         1  2  3  4  5 */
                   1223: /*           F  F  V  V  V */
                   1224: /*           D  Q  D  D  Q */
                   1225: /*                         */
                   1226: int *TvarsD;
                   1227: int *TvarsDind;
                   1228: int *TvarsQ;
                   1229: int *TvarsQind;
                   1230: 
1.235     brouard  1231: #define MAXRESULTLINES 10
                   1232: int nresult=0;
1.258     brouard  1233: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1234: int TKresult[MAXRESULTLINES];
1.237     brouard  1235: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1236: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1237: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1238: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1239: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1240: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1241: 
1.234     brouard  1242: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1243: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1244: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1245: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1246: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1247: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1248: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1249: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1250: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1251: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1252: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1253: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1254: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1255: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1256: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1257: 
1.230     brouard  1258: int *Tvarsel; /**< Selected covariates for output */
                   1259: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1260: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1261: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1262: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1263: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1264: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1265: int *Tage;
1.227     brouard  1266: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1267: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1268: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1269: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1270: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1271: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1272: int **Tvard;
                   1273: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1274: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1275: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1276:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1277:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1278: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1279: double *lsurv, *lpop, *tpop;
                   1280: 
1.231     brouard  1281: #define FD 1; /* Fixed dummy covariate */
                   1282: #define FQ 2; /* Fixed quantitative covariate */
                   1283: #define FP 3; /* Fixed product covariate */
                   1284: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1285: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1286: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1287: #define VD 10; /* Varying dummy covariate */
                   1288: #define VQ 11; /* Varying quantitative covariate */
                   1289: #define VP 12; /* Varying product covariate */
                   1290: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1291: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1292: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1293: #define APFD 16; /* Age product * fixed dummy covariate */
                   1294: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1295: #define APVD 18; /* Age product * varying dummy covariate */
                   1296: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1297: 
                   1298: #define FTYPE 1; /* Fixed covariate */
                   1299: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1300: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1301: 
                   1302: struct kmodel{
                   1303:        int maintype; /* main type */
                   1304:        int subtype; /* subtype */
                   1305: };
                   1306: struct kmodel modell[NCOVMAX];
                   1307: 
1.143     brouard  1308: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1309: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1310: 
                   1311: /**************** split *************************/
                   1312: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1313: {
                   1314:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1315:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1316:   */ 
                   1317:   char *ss;                            /* pointer */
1.186     brouard  1318:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1319: 
                   1320:   l1 = strlen(path );                  /* length of path */
                   1321:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1322:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1323:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1324:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1325:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1326:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1327:     /* get current working directory */
                   1328:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1329: #ifdef WIN32
                   1330:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1331: #else
                   1332:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1333: #endif
1.126     brouard  1334:       return( GLOCK_ERROR_GETCWD );
                   1335:     }
                   1336:     /* got dirc from getcwd*/
                   1337:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1338:   } else {                             /* strip directory from path */
1.126     brouard  1339:     ss++;                              /* after this, the filename */
                   1340:     l2 = strlen( ss );                 /* length of filename */
                   1341:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1342:     strcpy( name, ss );                /* save file name */
                   1343:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1344:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1345:     printf(" DIRC2 = %s \n",dirc);
                   1346:   }
                   1347:   /* We add a separator at the end of dirc if not exists */
                   1348:   l1 = strlen( dirc );                 /* length of directory */
                   1349:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1350:     dirc[l1] =  DIRSEPARATOR;
                   1351:     dirc[l1+1] = 0; 
                   1352:     printf(" DIRC3 = %s \n",dirc);
                   1353:   }
                   1354:   ss = strrchr( name, '.' );           /* find last / */
                   1355:   if (ss >0){
                   1356:     ss++;
                   1357:     strcpy(ext,ss);                    /* save extension */
                   1358:     l1= strlen( name);
                   1359:     l2= strlen(ss)+1;
                   1360:     strncpy( finame, name, l1-l2);
                   1361:     finame[l1-l2]= 0;
                   1362:   }
                   1363: 
                   1364:   return( 0 );                         /* we're done */
                   1365: }
                   1366: 
                   1367: 
                   1368: /******************************************/
                   1369: 
                   1370: void replace_back_to_slash(char *s, char*t)
                   1371: {
                   1372:   int i;
                   1373:   int lg=0;
                   1374:   i=0;
                   1375:   lg=strlen(t);
                   1376:   for(i=0; i<= lg; i++) {
                   1377:     (s[i] = t[i]);
                   1378:     if (t[i]== '\\') s[i]='/';
                   1379:   }
                   1380: }
                   1381: 
1.132     brouard  1382: char *trimbb(char *out, char *in)
1.137     brouard  1383: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1384:   char *s;
                   1385:   s=out;
                   1386:   while (*in != '\0'){
1.137     brouard  1387:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1388:       in++;
                   1389:     }
                   1390:     *out++ = *in++;
                   1391:   }
                   1392:   *out='\0';
                   1393:   return s;
                   1394: }
                   1395: 
1.187     brouard  1396: /* char *substrchaine(char *out, char *in, char *chain) */
                   1397: /* { */
                   1398: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1399: /*   char *s, *t; */
                   1400: /*   t=in;s=out; */
                   1401: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1402: /*     *out++ = *in++; */
                   1403: /*   } */
                   1404: 
                   1405: /*   /\* *in matches *chain *\/ */
                   1406: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1407: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1408: /*   } */
                   1409: /*   in--; chain--; */
                   1410: /*   while ( (*in != '\0')){ */
                   1411: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1412: /*     *out++ = *in++; */
                   1413: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1414: /*   } */
                   1415: /*   *out='\0'; */
                   1416: /*   out=s; */
                   1417: /*   return out; */
                   1418: /* } */
                   1419: char *substrchaine(char *out, char *in, char *chain)
                   1420: {
                   1421:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1422:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1423: 
                   1424:   char *strloc;
                   1425: 
                   1426:   strcpy (out, in); 
                   1427:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1428:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1429:   if(strloc != NULL){ 
                   1430:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1431:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1432:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1433:   }
                   1434:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1435:   return out;
                   1436: }
                   1437: 
                   1438: 
1.145     brouard  1439: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1440: {
1.187     brouard  1441:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1442:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1443:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1444:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1445:   */
1.160     brouard  1446:   char *s, *t;
1.145     brouard  1447:   t=in;s=in;
                   1448:   while ((*in != occ) && (*in != '\0')){
                   1449:     *alocc++ = *in++;
                   1450:   }
                   1451:   if( *in == occ){
                   1452:     *(alocc)='\0';
                   1453:     s=++in;
                   1454:   }
                   1455:  
                   1456:   if (s == t) {/* occ not found */
                   1457:     *(alocc-(in-s))='\0';
                   1458:     in=s;
                   1459:   }
                   1460:   while ( *in != '\0'){
                   1461:     *blocc++ = *in++;
                   1462:   }
                   1463: 
                   1464:   *blocc='\0';
                   1465:   return t;
                   1466: }
1.137     brouard  1467: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1468: {
1.187     brouard  1469:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1470:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1471:      gives blocc="abcdef2ghi" and alocc="j".
                   1472:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1473:   */
                   1474:   char *s, *t;
                   1475:   t=in;s=in;
                   1476:   while (*in != '\0'){
                   1477:     while( *in == occ){
                   1478:       *blocc++ = *in++;
                   1479:       s=in;
                   1480:     }
                   1481:     *blocc++ = *in++;
                   1482:   }
                   1483:   if (s == t) /* occ not found */
                   1484:     *(blocc-(in-s))='\0';
                   1485:   else
                   1486:     *(blocc-(in-s)-1)='\0';
                   1487:   in=s;
                   1488:   while ( *in != '\0'){
                   1489:     *alocc++ = *in++;
                   1490:   }
                   1491: 
                   1492:   *alocc='\0';
                   1493:   return s;
                   1494: }
                   1495: 
1.126     brouard  1496: int nbocc(char *s, char occ)
                   1497: {
                   1498:   int i,j=0;
                   1499:   int lg=20;
                   1500:   i=0;
                   1501:   lg=strlen(s);
                   1502:   for(i=0; i<= lg; i++) {
1.234     brouard  1503:     if  (s[i] == occ ) j++;
1.126     brouard  1504:   }
                   1505:   return j;
                   1506: }
                   1507: 
1.137     brouard  1508: /* void cutv(char *u,char *v, char*t, char occ) */
                   1509: /* { */
                   1510: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1511: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1512: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1513: /*   int i,lg,j,p=0; */
                   1514: /*   i=0; */
                   1515: /*   lg=strlen(t); */
                   1516: /*   for(j=0; j<=lg-1; j++) { */
                   1517: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1518: /*   } */
1.126     brouard  1519: 
1.137     brouard  1520: /*   for(j=0; j<p; j++) { */
                   1521: /*     (u[j] = t[j]); */
                   1522: /*   } */
                   1523: /*      u[p]='\0'; */
1.126     brouard  1524: 
1.137     brouard  1525: /*    for(j=0; j<= lg; j++) { */
                   1526: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1527: /*   } */
                   1528: /* } */
1.126     brouard  1529: 
1.160     brouard  1530: #ifdef _WIN32
                   1531: char * strsep(char **pp, const char *delim)
                   1532: {
                   1533:   char *p, *q;
                   1534:          
                   1535:   if ((p = *pp) == NULL)
                   1536:     return 0;
                   1537:   if ((q = strpbrk (p, delim)) != NULL)
                   1538:   {
                   1539:     *pp = q + 1;
                   1540:     *q = '\0';
                   1541:   }
                   1542:   else
                   1543:     *pp = 0;
                   1544:   return p;
                   1545: }
                   1546: #endif
                   1547: 
1.126     brouard  1548: /********************** nrerror ********************/
                   1549: 
                   1550: void nrerror(char error_text[])
                   1551: {
                   1552:   fprintf(stderr,"ERREUR ...\n");
                   1553:   fprintf(stderr,"%s\n",error_text);
                   1554:   exit(EXIT_FAILURE);
                   1555: }
                   1556: /*********************** vector *******************/
                   1557: double *vector(int nl, int nh)
                   1558: {
                   1559:   double *v;
                   1560:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1561:   if (!v) nrerror("allocation failure in vector");
                   1562:   return v-nl+NR_END;
                   1563: }
                   1564: 
                   1565: /************************ free vector ******************/
                   1566: void free_vector(double*v, int nl, int nh)
                   1567: {
                   1568:   free((FREE_ARG)(v+nl-NR_END));
                   1569: }
                   1570: 
                   1571: /************************ivector *******************************/
                   1572: int *ivector(long nl,long nh)
                   1573: {
                   1574:   int *v;
                   1575:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1576:   if (!v) nrerror("allocation failure in ivector");
                   1577:   return v-nl+NR_END;
                   1578: }
                   1579: 
                   1580: /******************free ivector **************************/
                   1581: void free_ivector(int *v, long nl, long nh)
                   1582: {
                   1583:   free((FREE_ARG)(v+nl-NR_END));
                   1584: }
                   1585: 
                   1586: /************************lvector *******************************/
                   1587: long *lvector(long nl,long nh)
                   1588: {
                   1589:   long *v;
                   1590:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1591:   if (!v) nrerror("allocation failure in ivector");
                   1592:   return v-nl+NR_END;
                   1593: }
                   1594: 
                   1595: /******************free lvector **************************/
                   1596: void free_lvector(long *v, long nl, long nh)
                   1597: {
                   1598:   free((FREE_ARG)(v+nl-NR_END));
                   1599: }
                   1600: 
                   1601: /******************* imatrix *******************************/
                   1602: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1603:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1604: { 
                   1605:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1606:   int **m; 
                   1607:   
                   1608:   /* allocate pointers to rows */ 
                   1609:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1610:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1611:   m += NR_END; 
                   1612:   m -= nrl; 
                   1613:   
                   1614:   
                   1615:   /* allocate rows and set pointers to them */ 
                   1616:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1617:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1618:   m[nrl] += NR_END; 
                   1619:   m[nrl] -= ncl; 
                   1620:   
                   1621:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1622:   
                   1623:   /* return pointer to array of pointers to rows */ 
                   1624:   return m; 
                   1625: } 
                   1626: 
                   1627: /****************** free_imatrix *************************/
                   1628: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1629:       int **m;
                   1630:       long nch,ncl,nrh,nrl; 
                   1631:      /* free an int matrix allocated by imatrix() */ 
                   1632: { 
                   1633:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1634:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1635: } 
                   1636: 
                   1637: /******************* matrix *******************************/
                   1638: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1639: {
                   1640:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1641:   double **m;
                   1642: 
                   1643:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1644:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1645:   m += NR_END;
                   1646:   m -= nrl;
                   1647: 
                   1648:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1649:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1650:   m[nrl] += NR_END;
                   1651:   m[nrl] -= ncl;
                   1652: 
                   1653:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1654:   return m;
1.145     brouard  1655:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1656: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1657: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1658:    */
                   1659: }
                   1660: 
                   1661: /*************************free matrix ************************/
                   1662: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1663: {
                   1664:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1665:   free((FREE_ARG)(m+nrl-NR_END));
                   1666: }
                   1667: 
                   1668: /******************* ma3x *******************************/
                   1669: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1670: {
                   1671:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1672:   double ***m;
                   1673: 
                   1674:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1675:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1676:   m += NR_END;
                   1677:   m -= nrl;
                   1678: 
                   1679:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1680:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1681:   m[nrl] += NR_END;
                   1682:   m[nrl] -= ncl;
                   1683: 
                   1684:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1685: 
                   1686:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1687:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1688:   m[nrl][ncl] += NR_END;
                   1689:   m[nrl][ncl] -= nll;
                   1690:   for (j=ncl+1; j<=nch; j++) 
                   1691:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1692:   
                   1693:   for (i=nrl+1; i<=nrh; i++) {
                   1694:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1695:     for (j=ncl+1; j<=nch; j++) 
                   1696:       m[i][j]=m[i][j-1]+nlay;
                   1697:   }
                   1698:   return m; 
                   1699:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1700:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1701:   */
                   1702: }
                   1703: 
                   1704: /*************************free ma3x ************************/
                   1705: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1706: {
                   1707:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1708:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1709:   free((FREE_ARG)(m+nrl-NR_END));
                   1710: }
                   1711: 
                   1712: /*************** function subdirf ***********/
                   1713: char *subdirf(char fileres[])
                   1714: {
                   1715:   /* Caution optionfilefiname is hidden */
                   1716:   strcpy(tmpout,optionfilefiname);
                   1717:   strcat(tmpout,"/"); /* Add to the right */
                   1718:   strcat(tmpout,fileres);
                   1719:   return tmpout;
                   1720: }
                   1721: 
                   1722: /*************** function subdirf2 ***********/
                   1723: char *subdirf2(char fileres[], char *preop)
                   1724: {
                   1725:   
                   1726:   /* Caution optionfilefiname is hidden */
                   1727:   strcpy(tmpout,optionfilefiname);
                   1728:   strcat(tmpout,"/");
                   1729:   strcat(tmpout,preop);
                   1730:   strcat(tmpout,fileres);
                   1731:   return tmpout;
                   1732: }
                   1733: 
                   1734: /*************** function subdirf3 ***********/
                   1735: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1736: {
                   1737:   
                   1738:   /* Caution optionfilefiname is hidden */
                   1739:   strcpy(tmpout,optionfilefiname);
                   1740:   strcat(tmpout,"/");
                   1741:   strcat(tmpout,preop);
                   1742:   strcat(tmpout,preop2);
                   1743:   strcat(tmpout,fileres);
                   1744:   return tmpout;
                   1745: }
1.213     brouard  1746:  
                   1747: /*************** function subdirfext ***********/
                   1748: char *subdirfext(char fileres[], char *preop, char *postop)
                   1749: {
                   1750:   
                   1751:   strcpy(tmpout,preop);
                   1752:   strcat(tmpout,fileres);
                   1753:   strcat(tmpout,postop);
                   1754:   return tmpout;
                   1755: }
1.126     brouard  1756: 
1.213     brouard  1757: /*************** function subdirfext3 ***********/
                   1758: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1759: {
                   1760:   
                   1761:   /* Caution optionfilefiname is hidden */
                   1762:   strcpy(tmpout,optionfilefiname);
                   1763:   strcat(tmpout,"/");
                   1764:   strcat(tmpout,preop);
                   1765:   strcat(tmpout,fileres);
                   1766:   strcat(tmpout,postop);
                   1767:   return tmpout;
                   1768: }
                   1769:  
1.162     brouard  1770: char *asc_diff_time(long time_sec, char ascdiff[])
                   1771: {
                   1772:   long sec_left, days, hours, minutes;
                   1773:   days = (time_sec) / (60*60*24);
                   1774:   sec_left = (time_sec) % (60*60*24);
                   1775:   hours = (sec_left) / (60*60) ;
                   1776:   sec_left = (sec_left) %(60*60);
                   1777:   minutes = (sec_left) /60;
                   1778:   sec_left = (sec_left) % (60);
                   1779:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1780:   return ascdiff;
                   1781: }
                   1782: 
1.126     brouard  1783: /***************** f1dim *************************/
                   1784: extern int ncom; 
                   1785: extern double *pcom,*xicom;
                   1786: extern double (*nrfunc)(double []); 
                   1787:  
                   1788: double f1dim(double x) 
                   1789: { 
                   1790:   int j; 
                   1791:   double f;
                   1792:   double *xt; 
                   1793:  
                   1794:   xt=vector(1,ncom); 
                   1795:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1796:   f=(*nrfunc)(xt); 
                   1797:   free_vector(xt,1,ncom); 
                   1798:   return f; 
                   1799: } 
                   1800: 
                   1801: /*****************brent *************************/
                   1802: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1803: {
                   1804:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1805:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1806:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1807:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1808:    * returned function value. 
                   1809:   */
1.126     brouard  1810:   int iter; 
                   1811:   double a,b,d,etemp;
1.159     brouard  1812:   double fu=0,fv,fw,fx;
1.164     brouard  1813:   double ftemp=0.;
1.126     brouard  1814:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1815:   double e=0.0; 
                   1816:  
                   1817:   a=(ax < cx ? ax : cx); 
                   1818:   b=(ax > cx ? ax : cx); 
                   1819:   x=w=v=bx; 
                   1820:   fw=fv=fx=(*f)(x); 
                   1821:   for (iter=1;iter<=ITMAX;iter++) { 
                   1822:     xm=0.5*(a+b); 
                   1823:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1824:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1825:     printf(".");fflush(stdout);
                   1826:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1827: #ifdef DEBUGBRENT
1.126     brouard  1828:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1829:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1830:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1831: #endif
                   1832:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1833:       *xmin=x; 
                   1834:       return fx; 
                   1835:     } 
                   1836:     ftemp=fu;
                   1837:     if (fabs(e) > tol1) { 
                   1838:       r=(x-w)*(fx-fv); 
                   1839:       q=(x-v)*(fx-fw); 
                   1840:       p=(x-v)*q-(x-w)*r; 
                   1841:       q=2.0*(q-r); 
                   1842:       if (q > 0.0) p = -p; 
                   1843:       q=fabs(q); 
                   1844:       etemp=e; 
                   1845:       e=d; 
                   1846:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1847:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1848:       else { 
1.224     brouard  1849:                                d=p/q; 
                   1850:                                u=x+d; 
                   1851:                                if (u-a < tol2 || b-u < tol2) 
                   1852:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1853:       } 
                   1854:     } else { 
                   1855:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1856:     } 
                   1857:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1858:     fu=(*f)(u); 
                   1859:     if (fu <= fx) { 
                   1860:       if (u >= x) a=x; else b=x; 
                   1861:       SHFT(v,w,x,u) 
1.183     brouard  1862:       SHFT(fv,fw,fx,fu) 
                   1863:     } else { 
                   1864:       if (u < x) a=u; else b=u; 
                   1865:       if (fu <= fw || w == x) { 
1.224     brouard  1866:                                v=w; 
                   1867:                                w=u; 
                   1868:                                fv=fw; 
                   1869:                                fw=fu; 
1.183     brouard  1870:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1871:                                v=u; 
                   1872:                                fv=fu; 
1.183     brouard  1873:       } 
                   1874:     } 
1.126     brouard  1875:   } 
                   1876:   nrerror("Too many iterations in brent"); 
                   1877:   *xmin=x; 
                   1878:   return fx; 
                   1879: } 
                   1880: 
                   1881: /****************** mnbrak ***********************/
                   1882: 
                   1883: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1884:            double (*func)(double)) 
1.183     brouard  1885: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1886: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1887: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1888: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1889:    */
1.126     brouard  1890:   double ulim,u,r,q, dum;
                   1891:   double fu; 
1.187     brouard  1892: 
                   1893:   double scale=10.;
                   1894:   int iterscale=0;
                   1895: 
                   1896:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1897:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1898: 
                   1899: 
                   1900:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1901:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1902:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1903:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1904:   /* } */
                   1905: 
1.126     brouard  1906:   if (*fb > *fa) { 
                   1907:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1908:     SHFT(dum,*fb,*fa,dum) 
                   1909:   } 
1.126     brouard  1910:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1911:   *fc=(*func)(*cx); 
1.183     brouard  1912: #ifdef DEBUG
1.224     brouard  1913:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1914:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1915: #endif
1.224     brouard  1916:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1917:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1918:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1919:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1920:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1921:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1922:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1923:       fu=(*func)(u); 
1.163     brouard  1924: #ifdef DEBUG
                   1925:       /* f(x)=A(x-u)**2+f(u) */
                   1926:       double A, fparabu; 
                   1927:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1928:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1929:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1930:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1931:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1932:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1933:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1934:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1935: #endif 
1.184     brouard  1936: #ifdef MNBRAKORIGINAL
1.183     brouard  1937: #else
1.191     brouard  1938: /*       if (fu > *fc) { */
                   1939: /* #ifdef DEBUG */
                   1940: /*       printf("mnbrak4  fu > fc \n"); */
                   1941: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1942: /* #endif */
                   1943: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1944: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1945: /*     dum=u; /\* Shifting c and u *\/ */
                   1946: /*     u = *cx; */
                   1947: /*     *cx = dum; */
                   1948: /*     dum = fu; */
                   1949: /*     fu = *fc; */
                   1950: /*     *fc =dum; */
                   1951: /*       } else { /\* end *\/ */
                   1952: /* #ifdef DEBUG */
                   1953: /*       printf("mnbrak3  fu < fc \n"); */
                   1954: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1955: /* #endif */
                   1956: /*     dum=u; /\* Shifting c and u *\/ */
                   1957: /*     u = *cx; */
                   1958: /*     *cx = dum; */
                   1959: /*     dum = fu; */
                   1960: /*     fu = *fc; */
                   1961: /*     *fc =dum; */
                   1962: /*       } */
1.224     brouard  1963: #ifdef DEBUGMNBRAK
                   1964:                 double A, fparabu; 
                   1965:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1966:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1967:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1968:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1969: #endif
1.191     brouard  1970:       dum=u; /* Shifting c and u */
                   1971:       u = *cx;
                   1972:       *cx = dum;
                   1973:       dum = fu;
                   1974:       fu = *fc;
                   1975:       *fc =dum;
1.183     brouard  1976: #endif
1.162     brouard  1977:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1978: #ifdef DEBUG
1.224     brouard  1979:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1980:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1981: #endif
1.126     brouard  1982:       fu=(*func)(u); 
                   1983:       if (fu < *fc) { 
1.183     brouard  1984: #ifdef DEBUG
1.224     brouard  1985:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1986:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1987: #endif
                   1988:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1989:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1990: #ifdef DEBUG
                   1991:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1992: #endif
                   1993:       } 
1.162     brouard  1994:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1995: #ifdef DEBUG
1.224     brouard  1996:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1997:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1998: #endif
1.126     brouard  1999:       u=ulim; 
                   2000:       fu=(*func)(u); 
1.183     brouard  2001:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2002: #ifdef DEBUG
1.224     brouard  2003:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2004:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2005: #endif
1.126     brouard  2006:       u=(*cx)+GOLD*(*cx-*bx); 
                   2007:       fu=(*func)(u); 
1.224     brouard  2008: #ifdef DEBUG
                   2009:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2010:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2011: #endif
1.183     brouard  2012:     } /* end tests */
1.126     brouard  2013:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2014:     SHFT(*fa,*fb,*fc,fu) 
                   2015: #ifdef DEBUG
1.224     brouard  2016:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2017:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2018: #endif
                   2019:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2020: } 
                   2021: 
                   2022: /*************** linmin ************************/
1.162     brouard  2023: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2024: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2025: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2026: the value of func at the returned location p . This is actually all accomplished by calling the
                   2027: routines mnbrak and brent .*/
1.126     brouard  2028: int ncom; 
                   2029: double *pcom,*xicom;
                   2030: double (*nrfunc)(double []); 
                   2031:  
1.224     brouard  2032: #ifdef LINMINORIGINAL
1.126     brouard  2033: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2034: #else
                   2035: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2036: #endif
1.126     brouard  2037: { 
                   2038:   double brent(double ax, double bx, double cx, 
                   2039:               double (*f)(double), double tol, double *xmin); 
                   2040:   double f1dim(double x); 
                   2041:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2042:              double *fc, double (*func)(double)); 
                   2043:   int j; 
                   2044:   double xx,xmin,bx,ax; 
                   2045:   double fx,fb,fa;
1.187     brouard  2046: 
1.203     brouard  2047: #ifdef LINMINORIGINAL
                   2048: #else
                   2049:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2050: #endif
                   2051:   
1.126     brouard  2052:   ncom=n; 
                   2053:   pcom=vector(1,n); 
                   2054:   xicom=vector(1,n); 
                   2055:   nrfunc=func; 
                   2056:   for (j=1;j<=n;j++) { 
                   2057:     pcom[j]=p[j]; 
1.202     brouard  2058:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2059:   } 
1.187     brouard  2060: 
1.203     brouard  2061: #ifdef LINMINORIGINAL
                   2062:   xx=1.;
                   2063: #else
                   2064:   axs=0.0;
                   2065:   xxs=1.;
                   2066:   do{
                   2067:     xx= xxs;
                   2068: #endif
1.187     brouard  2069:     ax=0.;
                   2070:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2071:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2072:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2073:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2074:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2075:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2076:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2077: #ifdef LINMINORIGINAL
                   2078: #else
                   2079:     if (fx != fx){
1.224     brouard  2080:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2081:                        printf("|");
                   2082:                        fprintf(ficlog,"|");
1.203     brouard  2083: #ifdef DEBUGLINMIN
1.224     brouard  2084:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2085: #endif
                   2086:     }
1.224     brouard  2087:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2088: #endif
                   2089:   
1.191     brouard  2090: #ifdef DEBUGLINMIN
                   2091:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2092:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2093: #endif
1.224     brouard  2094: #ifdef LINMINORIGINAL
                   2095: #else
                   2096:        if(fb == fx){ /* Flat function in the direction */
                   2097:                xmin=xx;
                   2098:     *flat=1;
                   2099:        }else{
                   2100:     *flat=0;
                   2101: #endif
                   2102:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2103:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2104:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2105:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2106:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2107:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2108: #ifdef DEBUG
1.224     brouard  2109:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2110:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2111: #endif
                   2112: #ifdef LINMINORIGINAL
                   2113: #else
                   2114:                        }
1.126     brouard  2115: #endif
1.191     brouard  2116: #ifdef DEBUGLINMIN
                   2117:   printf("linmin end ");
1.202     brouard  2118:   fprintf(ficlog,"linmin end ");
1.191     brouard  2119: #endif
1.126     brouard  2120:   for (j=1;j<=n;j++) { 
1.203     brouard  2121: #ifdef LINMINORIGINAL
                   2122:     xi[j] *= xmin; 
                   2123: #else
                   2124: #ifdef DEBUGLINMIN
                   2125:     if(xxs <1.0)
                   2126:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2127: #endif
                   2128:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2129: #ifdef DEBUGLINMIN
                   2130:     if(xxs <1.0)
                   2131:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2132: #endif
                   2133: #endif
1.187     brouard  2134:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2135:   } 
1.191     brouard  2136: #ifdef DEBUGLINMIN
1.203     brouard  2137:   printf("\n");
1.191     brouard  2138:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2139:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2140:   for (j=1;j<=n;j++) { 
1.202     brouard  2141:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2142:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2143:     if(j % ncovmodel == 0){
1.191     brouard  2144:       printf("\n");
1.202     brouard  2145:       fprintf(ficlog,"\n");
                   2146:     }
1.191     brouard  2147:   }
1.203     brouard  2148: #else
1.191     brouard  2149: #endif
1.126     brouard  2150:   free_vector(xicom,1,n); 
                   2151:   free_vector(pcom,1,n); 
                   2152: } 
                   2153: 
                   2154: 
                   2155: /*************** powell ************************/
1.162     brouard  2156: /*
                   2157: Minimization of a function func of n variables. Input consists of an initial starting point
                   2158: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2159: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2160: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2161: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2162: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2163:  */
1.224     brouard  2164: #ifdef LINMINORIGINAL
                   2165: #else
                   2166:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2167:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2168: #endif
1.126     brouard  2169: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2170:            double (*func)(double [])) 
                   2171: { 
1.224     brouard  2172: #ifdef LINMINORIGINAL
                   2173:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2174:              double (*func)(double [])); 
1.224     brouard  2175: #else 
1.241     brouard  2176:  void linmin(double p[], double xi[], int n, double *fret,
                   2177:             double (*func)(double []),int *flat); 
1.224     brouard  2178: #endif
1.239     brouard  2179:  int i,ibig,j,jk,k; 
1.126     brouard  2180:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2181:   double directest;
1.126     brouard  2182:   double fp,fptt;
                   2183:   double *xits;
                   2184:   int niterf, itmp;
1.224     brouard  2185: #ifdef LINMINORIGINAL
                   2186: #else
                   2187: 
                   2188:   flatdir=ivector(1,n); 
                   2189:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2190: #endif
1.126     brouard  2191: 
                   2192:   pt=vector(1,n); 
                   2193:   ptt=vector(1,n); 
                   2194:   xit=vector(1,n); 
                   2195:   xits=vector(1,n); 
                   2196:   *fret=(*func)(p); 
                   2197:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2198:   rcurr_time = time(NULL);  
1.126     brouard  2199:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2200:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2201:     ibig=0; 
                   2202:     del=0.0; 
1.157     brouard  2203:     rlast_time=rcurr_time;
                   2204:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2205:     rcurr_time = time(NULL);  
                   2206:     curr_time = *localtime(&rcurr_time);
                   2207:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2208:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2209: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2210:     for (i=1;i<=n;i++) {
1.126     brouard  2211:       fprintf(ficrespow," %.12lf", p[i]);
                   2212:     }
1.239     brouard  2213:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2214:     printf("\n#model=  1      +     age ");
                   2215:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2216:     if(nagesqr==1){
1.241     brouard  2217:        printf("  + age*age  ");
                   2218:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2219:     }
                   2220:     for(j=1;j <=ncovmodel-2;j++){
                   2221:       if(Typevar[j]==0) {
                   2222:        printf("  +      V%d  ",Tvar[j]);
                   2223:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2224:       }else if(Typevar[j]==1) {
                   2225:        printf("  +    V%d*age ",Tvar[j]);
                   2226:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2227:       }else if(Typevar[j]==2) {
                   2228:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2229:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2230:       }
                   2231:     }
1.126     brouard  2232:     printf("\n");
1.239     brouard  2233: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2234: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2235:     fprintf(ficlog,"\n");
1.239     brouard  2236:     for(i=1,jk=1; i <=nlstate; i++){
                   2237:       for(k=1; k <=(nlstate+ndeath); k++){
                   2238:        if (k != i) {
                   2239:          printf("%d%d ",i,k);
                   2240:          fprintf(ficlog,"%d%d ",i,k);
                   2241:          for(j=1; j <=ncovmodel; j++){
                   2242:            printf("%12.7f ",p[jk]);
                   2243:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2244:            jk++; 
                   2245:          }
                   2246:          printf("\n");
                   2247:          fprintf(ficlog,"\n");
                   2248:        }
                   2249:       }
                   2250:     }
1.241     brouard  2251:     if(*iter <=3 && *iter >1){
1.157     brouard  2252:       tml = *localtime(&rcurr_time);
                   2253:       strcpy(strcurr,asctime(&tml));
                   2254:       rforecast_time=rcurr_time; 
1.126     brouard  2255:       itmp = strlen(strcurr);
                   2256:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2257:        strcurr[itmp-1]='\0';
1.162     brouard  2258:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2259:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2260:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2261:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2262:        forecast_time = *localtime(&rforecast_time);
                   2263:        strcpy(strfor,asctime(&forecast_time));
                   2264:        itmp = strlen(strfor);
                   2265:        if(strfor[itmp-1]=='\n')
                   2266:          strfor[itmp-1]='\0';
                   2267:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2268:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2269:       }
                   2270:     }
1.187     brouard  2271:     for (i=1;i<=n;i++) { /* For each direction i */
                   2272:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2273:       fptt=(*fret); 
                   2274: #ifdef DEBUG
1.203     brouard  2275:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2276:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2277: #endif
1.203     brouard  2278:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2279:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2280: #ifdef LINMINORIGINAL
1.188     brouard  2281:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2282: #else
                   2283:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2284:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2285: #endif
                   2286:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2287:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2288:                                /* because that direction will be replaced unless the gain del is small */
                   2289:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2290:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2291:                                /* with the new direction. */
                   2292:                                del=fabs(fptt-(*fret)); 
                   2293:                                ibig=i; 
1.126     brouard  2294:       } 
                   2295: #ifdef DEBUG
                   2296:       printf("%d %.12e",i,(*fret));
                   2297:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2298:       for (j=1;j<=n;j++) {
1.224     brouard  2299:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2300:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2301:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2302:       }
                   2303:       for(j=1;j<=n;j++) {
1.225     brouard  2304:                                printf(" p(%d)=%.12e",j,p[j]);
                   2305:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2306:       }
                   2307:       printf("\n");
                   2308:       fprintf(ficlog,"\n");
                   2309: #endif
1.187     brouard  2310:     } /* end loop on each direction i */
                   2311:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2312:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2313:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2314:       for(j=1;j<=n;j++) {
1.225     brouard  2315:                                if(flatdir[j] >0){
                   2316:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2317:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2318:                                }
                   2319:                                /* printf("\n"); */
                   2320:                                /* fprintf(ficlog,"\n"); */
                   2321:                        }
1.243     brouard  2322:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2323:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2324:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2325:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2326:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2327:       /* decreased of more than 3.84  */
                   2328:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2329:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2330:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2331:                        
1.188     brouard  2332:       /* Starting the program with initial values given by a former maximization will simply change */
                   2333:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2334:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2335:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2336: #ifdef DEBUG
                   2337:       int k[2],l;
                   2338:       k[0]=1;
                   2339:       k[1]=-1;
                   2340:       printf("Max: %.12e",(*func)(p));
                   2341:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2342:       for (j=1;j<=n;j++) {
                   2343:        printf(" %.12e",p[j]);
                   2344:        fprintf(ficlog," %.12e",p[j]);
                   2345:       }
                   2346:       printf("\n");
                   2347:       fprintf(ficlog,"\n");
                   2348:       for(l=0;l<=1;l++) {
                   2349:        for (j=1;j<=n;j++) {
                   2350:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2351:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2352:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2353:        }
                   2354:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2355:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2356:       }
                   2357: #endif
                   2358: 
1.224     brouard  2359: #ifdef LINMINORIGINAL
                   2360: #else
                   2361:       free_ivector(flatdir,1,n); 
                   2362: #endif
1.126     brouard  2363:       free_vector(xit,1,n); 
                   2364:       free_vector(xits,1,n); 
                   2365:       free_vector(ptt,1,n); 
                   2366:       free_vector(pt,1,n); 
                   2367:       return; 
1.192     brouard  2368:     } /* enough precision */ 
1.240     brouard  2369:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2370:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2371:       ptt[j]=2.0*p[j]-pt[j]; 
                   2372:       xit[j]=p[j]-pt[j]; 
                   2373:       pt[j]=p[j]; 
                   2374:     } 
1.181     brouard  2375:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2376: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2377:                if (*iter <=4) {
1.225     brouard  2378: #else
                   2379: #endif
1.224     brouard  2380: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2381: #else
1.161     brouard  2382:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2383: #endif
1.162     brouard  2384:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2385:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2386:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2387:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2388:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2389:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2390:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2391:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2392:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2393:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2394:       /* mu² and del² are equal when f3=f1 */
                   2395:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2396:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2397:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2398:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2399: #ifdef NRCORIGINAL
                   2400:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2401: #else
                   2402:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2403:       t= t- del*SQR(fp-fptt);
1.183     brouard  2404: #endif
1.202     brouard  2405:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2406: #ifdef DEBUG
1.181     brouard  2407:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2408:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2409:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2410:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2411:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2412:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2413:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2414:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2415: #endif
1.183     brouard  2416: #ifdef POWELLORIGINAL
                   2417:       if (t < 0.0) { /* Then we use it for new direction */
                   2418: #else
1.182     brouard  2419:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2420:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2421:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2422:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2423:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2424:       } 
1.181     brouard  2425:       if (directest < 0.0) { /* Then we use it for new direction */
                   2426: #endif
1.191     brouard  2427: #ifdef DEBUGLINMIN
1.234     brouard  2428:        printf("Before linmin in direction P%d-P0\n",n);
                   2429:        for (j=1;j<=n;j++) {
                   2430:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2431:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2432:          if(j % ncovmodel == 0){
                   2433:            printf("\n");
                   2434:            fprintf(ficlog,"\n");
                   2435:          }
                   2436:        }
1.224     brouard  2437: #endif
                   2438: #ifdef LINMINORIGINAL
1.234     brouard  2439:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2440: #else
1.234     brouard  2441:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2442:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2443: #endif
1.234     brouard  2444:        
1.191     brouard  2445: #ifdef DEBUGLINMIN
1.234     brouard  2446:        for (j=1;j<=n;j++) { 
                   2447:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2448:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2449:          if(j % ncovmodel == 0){
                   2450:            printf("\n");
                   2451:            fprintf(ficlog,"\n");
                   2452:          }
                   2453:        }
1.224     brouard  2454: #endif
1.234     brouard  2455:        for (j=1;j<=n;j++) { 
                   2456:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2457:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2458:        }
1.224     brouard  2459: #ifdef LINMINORIGINAL
                   2460: #else
1.234     brouard  2461:        for (j=1, flatd=0;j<=n;j++) {
                   2462:          if(flatdir[j]>0)
                   2463:            flatd++;
                   2464:        }
                   2465:        if(flatd >0){
1.255     brouard  2466:          printf("%d flat directions: ",flatd);
                   2467:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2468:          for (j=1;j<=n;j++) { 
                   2469:            if(flatdir[j]>0){
                   2470:              printf("%d ",j);
                   2471:              fprintf(ficlog,"%d ",j);
                   2472:            }
                   2473:          }
                   2474:          printf("\n");
                   2475:          fprintf(ficlog,"\n");
                   2476:        }
1.191     brouard  2477: #endif
1.234     brouard  2478:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2479:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2480:        
1.126     brouard  2481: #ifdef DEBUG
1.234     brouard  2482:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2483:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2484:        for(j=1;j<=n;j++){
                   2485:          printf(" %lf",xit[j]);
                   2486:          fprintf(ficlog," %lf",xit[j]);
                   2487:        }
                   2488:        printf("\n");
                   2489:        fprintf(ficlog,"\n");
1.126     brouard  2490: #endif
1.192     brouard  2491:       } /* end of t or directest negative */
1.224     brouard  2492: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2493: #else
1.234     brouard  2494:       } /* end if (fptt < fp)  */
1.192     brouard  2495: #endif
1.225     brouard  2496: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2497:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2498: #else
1.224     brouard  2499: #endif
1.234     brouard  2500:                } /* loop iteration */ 
1.126     brouard  2501: } 
1.234     brouard  2502:   
1.126     brouard  2503: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2504:   
1.235     brouard  2505:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2506:   {
1.235     brouard  2507:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2508:        (and selected quantitative values in nres)
                   2509:        by left multiplying the unit
1.234     brouard  2510:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2511:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2512:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2513:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2514:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2515:   /* Initial matrix pimij */
                   2516:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2517:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2518:   /*  0,                   0                  , 1} */
                   2519:   /*
                   2520:    * and after some iteration: */
                   2521:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2522:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2523:   /*  0,                   0                  , 1} */
                   2524:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2525:   /* {0.51571254859325999, 0.4842874514067399, */
                   2526:   /*  0.51326036147820708, 0.48673963852179264} */
                   2527:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2528:     
1.126     brouard  2529:   int i, ii,j,k;
1.209     brouard  2530:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2531:   /* double **matprod2(); */ /* test */
1.218     brouard  2532:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2533:   double **newm;
1.209     brouard  2534:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2535:   int ncvloop=0;
1.169     brouard  2536:   
1.209     brouard  2537:   min=vector(1,nlstate);
                   2538:   max=vector(1,nlstate);
                   2539:   meandiff=vector(1,nlstate);
                   2540: 
1.218     brouard  2541:        /* Starting with matrix unity */
1.126     brouard  2542:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2543:     for (j=1;j<=nlstate+ndeath;j++){
                   2544:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2545:     }
1.169     brouard  2546:   
                   2547:   cov[1]=1.;
                   2548:   
                   2549:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2550:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2551:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2552:     ncvloop++;
1.126     brouard  2553:     newm=savm;
                   2554:     /* Covariates have to be included here again */
1.138     brouard  2555:     cov[2]=agefin;
1.187     brouard  2556:     if(nagesqr==1)
                   2557:       cov[3]= agefin*agefin;;
1.234     brouard  2558:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2559:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2560:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2561:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2562:     }
                   2563:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2564:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2565:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2566:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2567:     }
1.237     brouard  2568:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2569:       if(Dummy[Tvar[Tage[k]]]){
                   2570:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2571:       } else{
1.235     brouard  2572:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2573:       }
1.235     brouard  2574:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2575:     }
1.237     brouard  2576:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2577:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2578:       if(Dummy[Tvard[k][1]==0]){
                   2579:        if(Dummy[Tvard[k][2]==0]){
                   2580:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2581:        }else{
                   2582:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2583:        }
                   2584:       }else{
                   2585:        if(Dummy[Tvard[k][2]==0]){
                   2586:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2587:        }else{
                   2588:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2589:        }
                   2590:       }
1.234     brouard  2591:     }
1.138     brouard  2592:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2593:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2594:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2595:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2596:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2597:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2598:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2599:     
1.126     brouard  2600:     savm=oldm;
                   2601:     oldm=newm;
1.209     brouard  2602: 
                   2603:     for(j=1; j<=nlstate; j++){
                   2604:       max[j]=0.;
                   2605:       min[j]=1.;
                   2606:     }
                   2607:     for(i=1;i<=nlstate;i++){
                   2608:       sumnew=0;
                   2609:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2610:       for(j=1; j<=nlstate; j++){ 
                   2611:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2612:        max[j]=FMAX(max[j],prlim[i][j]);
                   2613:        min[j]=FMIN(min[j],prlim[i][j]);
                   2614:       }
                   2615:     }
                   2616: 
1.126     brouard  2617:     maxmax=0.;
1.209     brouard  2618:     for(j=1; j<=nlstate; j++){
                   2619:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2620:       maxmax=FMAX(maxmax,meandiff[j]);
                   2621:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2622:     } /* j loop */
1.203     brouard  2623:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2624:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2625:     if(maxmax < ftolpl){
1.209     brouard  2626:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2627:       free_vector(min,1,nlstate);
                   2628:       free_vector(max,1,nlstate);
                   2629:       free_vector(meandiff,1,nlstate);
1.126     brouard  2630:       return prlim;
                   2631:     }
1.169     brouard  2632:   } /* age loop */
1.208     brouard  2633:     /* After some age loop it doesn't converge */
1.209     brouard  2634:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2635: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2636:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2637:   free_vector(min,1,nlstate);
                   2638:   free_vector(max,1,nlstate);
                   2639:   free_vector(meandiff,1,nlstate);
1.208     brouard  2640:   
1.169     brouard  2641:   return prlim; /* should not reach here */
1.126     brouard  2642: }
                   2643: 
1.217     brouard  2644: 
                   2645:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2646: 
1.218     brouard  2647:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2648:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2649:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2650: {
1.264     brouard  2651:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2652:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2653:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2654:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2655:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2656:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2657:   /* Initial matrix pimij */
                   2658:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2659:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2660:   /*  0,                   0                  , 1} */
                   2661:   /*
                   2662:    * and after some iteration: */
                   2663:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2664:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2665:   /*  0,                   0                  , 1} */
                   2666:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2667:   /* {0.51571254859325999, 0.4842874514067399, */
                   2668:   /*  0.51326036147820708, 0.48673963852179264} */
                   2669:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2670: 
                   2671:   int i, ii,j,k;
1.247     brouard  2672:   int first=0;
1.217     brouard  2673:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2674:   /* double **matprod2(); */ /* test */
                   2675:   double **out, cov[NCOVMAX+1], **bmij();
                   2676:   double **newm;
1.218     brouard  2677:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2678:   double        **oldm, **savm;  /* for use */
                   2679: 
1.217     brouard  2680:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2681:   int ncvloop=0;
                   2682:   
                   2683:   min=vector(1,nlstate);
                   2684:   max=vector(1,nlstate);
                   2685:   meandiff=vector(1,nlstate);
                   2686: 
1.266     brouard  2687:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2688:   oldm=oldms; savm=savms;
                   2689:   
                   2690:   /* Starting with matrix unity */
                   2691:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2692:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2693:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2694:     }
                   2695:   
                   2696:   cov[1]=1.;
                   2697:   
                   2698:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2699:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2700:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2701:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2702:     ncvloop++;
1.218     brouard  2703:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2704:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2705:     /* Covariates have to be included here again */
                   2706:     cov[2]=agefin;
                   2707:     if(nagesqr==1)
                   2708:       cov[3]= agefin*agefin;;
1.242     brouard  2709:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2710:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2711:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2712:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2713:     }
                   2714:     /* for (k=1; k<=cptcovn;k++) { */
                   2715:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2716:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2717:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2718:     /* } */
                   2719:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2720:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2721:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2722:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2723:     }
                   2724:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2725:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2726:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2727:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2728:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2729:       if(Dummy[Tvar[Tage[k]]]){
                   2730:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2731:       } else{
                   2732:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2733:       }
                   2734:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2735:     }
                   2736:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2737:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2738:       if(Dummy[Tvard[k][1]==0]){
                   2739:        if(Dummy[Tvard[k][2]==0]){
                   2740:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2741:        }else{
                   2742:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2743:        }
                   2744:       }else{
                   2745:        if(Dummy[Tvard[k][2]==0]){
                   2746:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2747:        }else{
                   2748:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2749:        }
                   2750:       }
1.217     brouard  2751:     }
                   2752:     
                   2753:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2754:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2755:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2756:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2757:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2758:                /* ij should be linked to the correct index of cov */
                   2759:                /* age and covariate values ij are in 'cov', but we need to pass
                   2760:                 * ij for the observed prevalence at age and status and covariate
                   2761:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2762:                 */
                   2763:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2764:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2765:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2766:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2767:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2768:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2769:     /*         printf("%d newm= ",i); */
                   2770:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2771:     /*           printf("%f ",newm[i][j]); */
                   2772:     /*         } */
                   2773:     /*         printf("oldm * "); */
                   2774:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2775:     /*           printf("%f ",oldm[i][j]); */
                   2776:     /*         } */
1.268     brouard  2777:     /*         printf(" bmmij "); */
1.266     brouard  2778:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2779:     /*           printf("%f ",pmmij[i][j]); */
                   2780:     /*         } */
                   2781:     /*         printf("\n"); */
                   2782:     /*   } */
                   2783:     /* } */
1.217     brouard  2784:     savm=oldm;
                   2785:     oldm=newm;
1.266     brouard  2786: 
1.217     brouard  2787:     for(j=1; j<=nlstate; j++){
                   2788:       max[j]=0.;
                   2789:       min[j]=1.;
                   2790:     }
                   2791:     for(j=1; j<=nlstate; j++){ 
                   2792:       for(i=1;i<=nlstate;i++){
1.234     brouard  2793:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2794:        bprlim[i][j]= newm[i][j];
                   2795:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2796:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2797:       }
                   2798:     }
1.218     brouard  2799:                
1.217     brouard  2800:     maxmax=0.;
                   2801:     for(i=1; i<=nlstate; i++){
                   2802:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2803:       maxmax=FMAX(maxmax,meandiff[i]);
                   2804:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2805:     } /* i loop */
1.217     brouard  2806:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2807:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2808:     if(maxmax < ftolpl){
1.220     brouard  2809:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2810:       free_vector(min,1,nlstate);
                   2811:       free_vector(max,1,nlstate);
                   2812:       free_vector(meandiff,1,nlstate);
                   2813:       return bprlim;
                   2814:     }
                   2815:   } /* age loop */
                   2816:     /* After some age loop it doesn't converge */
1.247     brouard  2817:   if(first){
                   2818:     first=1;
                   2819:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2820: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2821:   }
                   2822:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2823: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2824:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2825:   free_vector(min,1,nlstate);
                   2826:   free_vector(max,1,nlstate);
                   2827:   free_vector(meandiff,1,nlstate);
                   2828:   
                   2829:   return bprlim; /* should not reach here */
                   2830: }
                   2831: 
1.126     brouard  2832: /*************** transition probabilities ***************/ 
                   2833: 
                   2834: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2835: {
1.138     brouard  2836:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2837:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2838:      model to the ncovmodel covariates (including constant and age).
                   2839:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2840:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2841:      ncth covariate in the global vector x is given by the formula:
                   2842:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2843:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2844:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2845:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2846:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2847:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2848:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2849:   */
                   2850:   double s1, lnpijopii;
1.126     brouard  2851:   /*double t34;*/
1.164     brouard  2852:   int i,j, nc, ii, jj;
1.126     brouard  2853: 
1.223     brouard  2854:   for(i=1; i<= nlstate; i++){
                   2855:     for(j=1; j<i;j++){
                   2856:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2857:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2858:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2859:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2860:       }
                   2861:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2862:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2863:     }
                   2864:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2865:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2866:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2867:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2868:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2869:       }
                   2870:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2871:     }
                   2872:   }
1.218     brouard  2873:   
1.223     brouard  2874:   for(i=1; i<= nlstate; i++){
                   2875:     s1=0;
                   2876:     for(j=1; j<i; j++){
                   2877:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2878:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2879:     }
                   2880:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2881:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2882:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2883:     }
                   2884:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2885:     ps[i][i]=1./(s1+1.);
                   2886:     /* Computing other pijs */
                   2887:     for(j=1; j<i; j++)
                   2888:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2889:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2890:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2891:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2892:   } /* end i */
1.218     brouard  2893:   
1.223     brouard  2894:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2895:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2896:       ps[ii][jj]=0;
                   2897:       ps[ii][ii]=1;
                   2898:     }
                   2899:   }
1.218     brouard  2900:   
                   2901:   
1.223     brouard  2902:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2903:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2904:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2905:   /*   } */
                   2906:   /*   printf("\n "); */
                   2907:   /* } */
                   2908:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2909:   /*
                   2910:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2911:                goto end;*/
1.266     brouard  2912:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2913: }
                   2914: 
1.218     brouard  2915: /*************** backward transition probabilities ***************/ 
                   2916: 
                   2917:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2918: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2919:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2920: {
1.266     brouard  2921:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2922:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2923:    */
1.218     brouard  2924:   int i, ii, j,k;
1.222     brouard  2925:   
                   2926:   double **out, **pmij();
                   2927:   double sumnew=0.;
1.218     brouard  2928:   double agefin;
1.268     brouard  2929:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2930:   double **dnewm, **dsavm, **doldm;
                   2931:   double **bbmij;
                   2932:   
1.218     brouard  2933:   doldm=ddoldms; /* global pointers */
1.222     brouard  2934:   dnewm=ddnewms;
                   2935:   dsavm=ddsavms;
                   2936:   
                   2937:   agefin=cov[2];
1.268     brouard  2938:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2939:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2940:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2941:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2942: 
                   2943:   /* P_x */
1.266     brouard  2944:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2945:   /* outputs pmmij which is a stochastic matrix in row */
                   2946: 
                   2947:   /* Diag(w_x) */
                   2948:   /* Problem with prevacurrent which can be zero */
                   2949:   sumnew=0.;
1.269     brouard  2950:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2951:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2952:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2953:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2954:   }
                   2955:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2956:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2957:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2958:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2959:     }
                   2960:   }else{
                   2961:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2962:       for (j=1;j<=nlstate+ndeath;j++)
                   2963:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2964:     }
                   2965:     /* if(sumnew <0.9){ */
                   2966:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2967:     /* } */
                   2968:   }
                   2969:   k3=0.0;  /* We put the last diagonal to 0 */
                   2970:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2971:       doldm[ii][ii]= k3;
                   2972:   }
                   2973:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2974:   
                   2975:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2976:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2977: 
                   2978:   /* Diag(Sum_i w^i_x p^ij_x */
                   2979:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2980:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2981:     sumnew=0.;
1.222     brouard  2982:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2983:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2984:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2985:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2986:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2987:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2988:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2989:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2990:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2991:        /* }else */
1.268     brouard  2992:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2993:     } /*End ii */
                   2994:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2995: 
                   2996:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2997:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2998:   /* end bmij */
1.266     brouard  2999:   return ps; /*pointer is unchanged */
1.218     brouard  3000: }
1.217     brouard  3001: /*************** transition probabilities ***************/ 
                   3002: 
1.218     brouard  3003: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3004: {
                   3005:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3006:      computes the probability to be observed in state j being in state i by appying the
                   3007:      model to the ncovmodel covariates (including constant and age).
                   3008:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3009:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3010:      ncth covariate in the global vector x is given by the formula:
                   3011:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3012:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3013:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3014:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3015:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3016:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3017:   */
                   3018:   double s1, lnpijopii;
                   3019:   /*double t34;*/
                   3020:   int i,j, nc, ii, jj;
                   3021: 
1.234     brouard  3022:   for(i=1; i<= nlstate; i++){
                   3023:     for(j=1; j<i;j++){
                   3024:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3025:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3026:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3027:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3028:       }
                   3029:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3030:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3031:     }
                   3032:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3033:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3034:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3035:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3036:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3037:       }
                   3038:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3039:     }
                   3040:   }
                   3041:   
                   3042:   for(i=1; i<= nlstate; i++){
                   3043:     s1=0;
                   3044:     for(j=1; j<i; j++){
                   3045:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3046:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3047:     }
                   3048:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3049:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3050:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3051:     }
                   3052:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3053:     ps[i][i]=1./(s1+1.);
                   3054:     /* Computing other pijs */
                   3055:     for(j=1; j<i; j++)
                   3056:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3057:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3058:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3059:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3060:   } /* end i */
                   3061:   
                   3062:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3063:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3064:       ps[ii][jj]=0;
                   3065:       ps[ii][ii]=1;
                   3066:     }
                   3067:   }
                   3068:   /* Added for backcast */ /* Transposed matrix too */
                   3069:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3070:     s1=0.;
                   3071:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3072:       s1+=ps[ii][jj];
                   3073:     }
                   3074:     for(ii=1; ii<= nlstate; ii++){
                   3075:       ps[ii][jj]=ps[ii][jj]/s1;
                   3076:     }
                   3077:   }
                   3078:   /* Transposition */
                   3079:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3080:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3081:       s1=ps[ii][jj];
                   3082:       ps[ii][jj]=ps[jj][ii];
                   3083:       ps[jj][ii]=s1;
                   3084:     }
                   3085:   }
                   3086:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3087:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3088:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3089:   /*   } */
                   3090:   /*   printf("\n "); */
                   3091:   /* } */
                   3092:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3093:   /*
                   3094:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3095:     goto end;*/
                   3096:   return ps;
1.217     brouard  3097: }
                   3098: 
                   3099: 
1.126     brouard  3100: /**************** Product of 2 matrices ******************/
                   3101: 
1.145     brouard  3102: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3103: {
                   3104:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3105:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3106:   /* in, b, out are matrice of pointers which should have been initialized 
                   3107:      before: only the contents of out is modified. The function returns
                   3108:      a pointer to pointers identical to out */
1.145     brouard  3109:   int i, j, k;
1.126     brouard  3110:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3111:     for(k=ncolol; k<=ncoloh; k++){
                   3112:       out[i][k]=0.;
                   3113:       for(j=ncl; j<=nch; j++)
                   3114:        out[i][k] +=in[i][j]*b[j][k];
                   3115:     }
1.126     brouard  3116:   return out;
                   3117: }
                   3118: 
                   3119: 
                   3120: /************* Higher Matrix Product ***************/
                   3121: 
1.235     brouard  3122: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3123: {
1.218     brouard  3124:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3125:      'nhstepm*hstepm*stepm' months (i.e. until
                   3126:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3127:      nhstepm*hstepm matrices. 
                   3128:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3129:      (typically every 2 years instead of every month which is too big 
                   3130:      for the memory).
                   3131:      Model is determined by parameters x and covariates have to be 
                   3132:      included manually here. 
                   3133: 
                   3134:      */
                   3135: 
                   3136:   int i, j, d, h, k;
1.131     brouard  3137:   double **out, cov[NCOVMAX+1];
1.126     brouard  3138:   double **newm;
1.187     brouard  3139:   double agexact;
1.214     brouard  3140:   double agebegin, ageend;
1.126     brouard  3141: 
                   3142:   /* Hstepm could be zero and should return the unit matrix */
                   3143:   for (i=1;i<=nlstate+ndeath;i++)
                   3144:     for (j=1;j<=nlstate+ndeath;j++){
                   3145:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3146:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3147:     }
                   3148:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3149:   for(h=1; h <=nhstepm; h++){
                   3150:     for(d=1; d <=hstepm; d++){
                   3151:       newm=savm;
                   3152:       /* Covariates have to be included here again */
                   3153:       cov[1]=1.;
1.214     brouard  3154:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3155:       cov[2]=agexact;
                   3156:       if(nagesqr==1)
1.227     brouard  3157:        cov[3]= agexact*agexact;
1.235     brouard  3158:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3159:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3160:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3161:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3162:       }
                   3163:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3164:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3165:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3166:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3167:       }
                   3168:       for (k=1; k<=cptcovage;k++){
                   3169:        if(Dummy[Tvar[Tage[k]]]){
                   3170:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3171:        } else{
                   3172:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3173:        }
                   3174:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3175:       }
                   3176:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3177:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3178:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3179:       }
                   3180:       /* for (k=1; k<=cptcovn;k++)  */
                   3181:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3182:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3183:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3184:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3185:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3186:       
                   3187:       
1.126     brouard  3188:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3189:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3190:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3191:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3192:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3193:       /* if((int)age == 70){ */
                   3194:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3195:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3196:       /*         printf("%d pmmij ",i); */
                   3197:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3198:       /*           printf("%f ",pmmij[i][j]); */
                   3199:       /*         } */
                   3200:       /*         printf(" oldm "); */
                   3201:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3202:       /*           printf("%f ",oldm[i][j]); */
                   3203:       /*         } */
                   3204:       /*         printf("\n"); */
                   3205:       /*       } */
                   3206:       /* } */
1.126     brouard  3207:       savm=oldm;
                   3208:       oldm=newm;
                   3209:     }
                   3210:     for(i=1; i<=nlstate+ndeath; i++)
                   3211:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3212:        po[i][j][h]=newm[i][j];
                   3213:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3214:       }
1.128     brouard  3215:     /*printf("h=%d ",h);*/
1.126     brouard  3216:   } /* end h */
1.267     brouard  3217:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3218:   return po;
                   3219: }
                   3220: 
1.217     brouard  3221: /************* Higher Back Matrix Product ***************/
1.218     brouard  3222: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3223: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3224: {
1.266     brouard  3225:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3226:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3227:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3228:      nhstepm*hstepm matrices.
                   3229:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3230:      (typically every 2 years instead of every month which is too big
1.217     brouard  3231:      for the memory).
1.218     brouard  3232:      Model is determined by parameters x and covariates have to be
1.266     brouard  3233:      included manually here. Then we use a call to bmij(x and cov)
                   3234:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3235:   */
1.217     brouard  3236: 
                   3237:   int i, j, d, h, k;
1.266     brouard  3238:   double **out, cov[NCOVMAX+1], **bmij();
                   3239:   double **newm, ***newmm;
1.217     brouard  3240:   double agexact;
                   3241:   double agebegin, ageend;
1.222     brouard  3242:   double **oldm, **savm;
1.217     brouard  3243: 
1.266     brouard  3244:   newmm=po; /* To be saved */
                   3245:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3246:   /* Hstepm could be zero and should return the unit matrix */
                   3247:   for (i=1;i<=nlstate+ndeath;i++)
                   3248:     for (j=1;j<=nlstate+ndeath;j++){
                   3249:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3250:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3251:     }
                   3252:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3253:   for(h=1; h <=nhstepm; h++){
                   3254:     for(d=1; d <=hstepm; d++){
                   3255:       newm=savm;
                   3256:       /* Covariates have to be included here again */
                   3257:       cov[1]=1.;
1.271     brouard  3258:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3259:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3260:       cov[2]=agexact;
                   3261:       if(nagesqr==1)
1.222     brouard  3262:        cov[3]= agexact*agexact;
1.266     brouard  3263:       for (k=1; k<=cptcovn;k++){
                   3264:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3265:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3266:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3267:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3268:       }
1.267     brouard  3269:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3270:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3271:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3272:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3273:       }
                   3274:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3275:        if(Dummy[Tvar[Tage[k]]]){
                   3276:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3277:        } else{
                   3278:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3279:        }
                   3280:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3281:       }
                   3282:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3283:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3284:       }                        
1.217     brouard  3285:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3286:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3287: 
1.218     brouard  3288:       /* Careful transposed matrix */
1.266     brouard  3289:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3290:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3291:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3292:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3293:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3294:       /* if((int)age == 70){ */
                   3295:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3296:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3297:       /*         printf("%d pmmij ",i); */
                   3298:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3299:       /*           printf("%f ",pmmij[i][j]); */
                   3300:       /*         } */
                   3301:       /*         printf(" oldm "); */
                   3302:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3303:       /*           printf("%f ",oldm[i][j]); */
                   3304:       /*         } */
                   3305:       /*         printf("\n"); */
                   3306:       /*       } */
                   3307:       /* } */
                   3308:       savm=oldm;
                   3309:       oldm=newm;
                   3310:     }
                   3311:     for(i=1; i<=nlstate+ndeath; i++)
                   3312:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3313:        po[i][j][h]=newm[i][j];
1.268     brouard  3314:        /* if(h==nhstepm) */
                   3315:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3316:       }
1.268     brouard  3317:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3318:   } /* end h */
1.268     brouard  3319:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3320:   return po;
                   3321: }
                   3322: 
                   3323: 
1.162     brouard  3324: #ifdef NLOPT
                   3325:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3326:   double fret;
                   3327:   double *xt;
                   3328:   int j;
                   3329:   myfunc_data *d2 = (myfunc_data *) pd;
                   3330: /* xt = (p1-1); */
                   3331:   xt=vector(1,n); 
                   3332:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3333: 
                   3334:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3335:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3336:   printf("Function = %.12lf ",fret);
                   3337:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3338:   printf("\n");
                   3339:  free_vector(xt,1,n);
                   3340:   return fret;
                   3341: }
                   3342: #endif
1.126     brouard  3343: 
                   3344: /*************** log-likelihood *************/
                   3345: double func( double *x)
                   3346: {
1.226     brouard  3347:   int i, ii, j, k, mi, d, kk;
                   3348:   int ioffset=0;
                   3349:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3350:   double **out;
                   3351:   double lli; /* Individual log likelihood */
                   3352:   int s1, s2;
1.228     brouard  3353:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3354:   double bbh, survp;
                   3355:   long ipmx;
                   3356:   double agexact;
                   3357:   /*extern weight */
                   3358:   /* We are differentiating ll according to initial status */
                   3359:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3360:   /*for(i=1;i<imx;i++) 
                   3361:     printf(" %d\n",s[4][i]);
                   3362:   */
1.162     brouard  3363: 
1.226     brouard  3364:   ++countcallfunc;
1.162     brouard  3365: 
1.226     brouard  3366:   cov[1]=1.;
1.126     brouard  3367: 
1.226     brouard  3368:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3369:   ioffset=0;
1.226     brouard  3370:   if(mle==1){
                   3371:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3372:       /* Computes the values of the ncovmodel covariates of the model
                   3373:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3374:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3375:         to be observed in j being in i according to the model.
                   3376:       */
1.243     brouard  3377:       ioffset=2+nagesqr ;
1.233     brouard  3378:    /* Fixed */
1.234     brouard  3379:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3380:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3381:       }
1.226     brouard  3382:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3383:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3384:         has been calculated etc */
                   3385:       /* For an individual i, wav[i] gives the number of effective waves */
                   3386:       /* We compute the contribution to Likelihood of each effective transition
                   3387:         mw[mi][i] is real wave of the mi th effectve wave */
                   3388:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3389:         s2=s[mw[mi+1][i]][i];
                   3390:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3391:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3392:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3393:       */
                   3394:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3395:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3396:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3397:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3398:        }
                   3399:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3400:          for (j=1;j<=nlstate+ndeath;j++){
                   3401:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3402:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3403:          }
                   3404:        for(d=0; d<dh[mi][i]; d++){
                   3405:          newm=savm;
                   3406:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3407:          cov[2]=agexact;
                   3408:          if(nagesqr==1)
                   3409:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3410:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3411:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3412:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3413:          else
                   3414:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3415:          }
                   3416:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3417:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3418:          savm=oldm;
                   3419:          oldm=newm;
                   3420:        } /* end mult */
                   3421:        
                   3422:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3423:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3424:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3425:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3426:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3427:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3428:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3429:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3430:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3431:                                 * -stepm/2 to stepm/2 .
                   3432:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3433:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3434:                                 */
1.234     brouard  3435:        s1=s[mw[mi][i]][i];
                   3436:        s2=s[mw[mi+1][i]][i];
                   3437:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3438:        /* bias bh is positive if real duration
                   3439:         * is higher than the multiple of stepm and negative otherwise.
                   3440:         */
                   3441:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3442:        if( s2 > nlstate){ 
                   3443:          /* i.e. if s2 is a death state and if the date of death is known 
                   3444:             then the contribution to the likelihood is the probability to 
                   3445:             die between last step unit time and current  step unit time, 
                   3446:             which is also equal to probability to die before dh 
                   3447:             minus probability to die before dh-stepm . 
                   3448:             In version up to 0.92 likelihood was computed
                   3449:             as if date of death was unknown. Death was treated as any other
                   3450:             health state: the date of the interview describes the actual state
                   3451:             and not the date of a change in health state. The former idea was
                   3452:             to consider that at each interview the state was recorded
                   3453:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3454:             introduced the exact date of death then we should have modified
                   3455:             the contribution of an exact death to the likelihood. This new
                   3456:             contribution is smaller and very dependent of the step unit
                   3457:             stepm. It is no more the probability to die between last interview
                   3458:             and month of death but the probability to survive from last
                   3459:             interview up to one month before death multiplied by the
                   3460:             probability to die within a month. Thanks to Chris
                   3461:             Jackson for correcting this bug.  Former versions increased
                   3462:             mortality artificially. The bad side is that we add another loop
                   3463:             which slows down the processing. The difference can be up to 10%
                   3464:             lower mortality.
                   3465:          */
                   3466:          /* If, at the beginning of the maximization mostly, the
                   3467:             cumulative probability or probability to be dead is
                   3468:             constant (ie = 1) over time d, the difference is equal to
                   3469:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3470:             s1 at precedent wave, to be dead a month before current
                   3471:             wave is equal to probability, being at state s1 at
                   3472:             precedent wave, to be dead at mont of the current
                   3473:             wave. Then the observed probability (that this person died)
                   3474:             is null according to current estimated parameter. In fact,
                   3475:             it should be very low but not zero otherwise the log go to
                   3476:             infinity.
                   3477:          */
1.183     brouard  3478: /* #ifdef INFINITYORIGINAL */
                   3479: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3480: /* #else */
                   3481: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3482: /*         lli=log(mytinydouble); */
                   3483: /*       else */
                   3484: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3485: /* #endif */
1.226     brouard  3486:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3487:          
1.226     brouard  3488:        } else if  ( s2==-1 ) { /* alive */
                   3489:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3490:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3491:          /*survp += out[s1][j]; */
                   3492:          lli= log(survp);
                   3493:        }
                   3494:        else if  (s2==-4) { 
                   3495:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3496:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3497:          lli= log(survp); 
                   3498:        } 
                   3499:        else if  (s2==-5) { 
                   3500:          for (j=1,survp=0. ; j<=2; j++)  
                   3501:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3502:          lli= log(survp); 
                   3503:        } 
                   3504:        else{
                   3505:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3506:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3507:        } 
                   3508:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3509:        /*if(lli ==000.0)*/
                   3510:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3511:        ipmx +=1;
                   3512:        sw += weight[i];
                   3513:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3514:        /* if (lli < log(mytinydouble)){ */
                   3515:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3516:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3517:        /* } */
                   3518:       } /* end of wave */
                   3519:     } /* end of individual */
                   3520:   }  else if(mle==2){
                   3521:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3522:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3523:       for(mi=1; mi<= wav[i]-1; mi++){
                   3524:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3525:          for (j=1;j<=nlstate+ndeath;j++){
                   3526:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3527:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3528:          }
                   3529:        for(d=0; d<=dh[mi][i]; d++){
                   3530:          newm=savm;
                   3531:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3532:          cov[2]=agexact;
                   3533:          if(nagesqr==1)
                   3534:            cov[3]= agexact*agexact;
                   3535:          for (kk=1; kk<=cptcovage;kk++) {
                   3536:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3537:          }
                   3538:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3539:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3540:          savm=oldm;
                   3541:          oldm=newm;
                   3542:        } /* end mult */
                   3543:       
                   3544:        s1=s[mw[mi][i]][i];
                   3545:        s2=s[mw[mi+1][i]][i];
                   3546:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3547:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3548:        ipmx +=1;
                   3549:        sw += weight[i];
                   3550:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3551:       } /* end of wave */
                   3552:     } /* end of individual */
                   3553:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3554:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3555:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3556:       for(mi=1; mi<= wav[i]-1; mi++){
                   3557:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3558:          for (j=1;j<=nlstate+ndeath;j++){
                   3559:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3560:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3561:          }
                   3562:        for(d=0; d<dh[mi][i]; d++){
                   3563:          newm=savm;
                   3564:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3565:          cov[2]=agexact;
                   3566:          if(nagesqr==1)
                   3567:            cov[3]= agexact*agexact;
                   3568:          for (kk=1; kk<=cptcovage;kk++) {
                   3569:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3570:          }
                   3571:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3572:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3573:          savm=oldm;
                   3574:          oldm=newm;
                   3575:        } /* end mult */
                   3576:       
                   3577:        s1=s[mw[mi][i]][i];
                   3578:        s2=s[mw[mi+1][i]][i];
                   3579:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3580:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3581:        ipmx +=1;
                   3582:        sw += weight[i];
                   3583:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3584:       } /* end of wave */
                   3585:     } /* end of individual */
                   3586:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3587:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3588:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3589:       for(mi=1; mi<= wav[i]-1; mi++){
                   3590:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3591:          for (j=1;j<=nlstate+ndeath;j++){
                   3592:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3593:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3594:          }
                   3595:        for(d=0; d<dh[mi][i]; d++){
                   3596:          newm=savm;
                   3597:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3598:          cov[2]=agexact;
                   3599:          if(nagesqr==1)
                   3600:            cov[3]= agexact*agexact;
                   3601:          for (kk=1; kk<=cptcovage;kk++) {
                   3602:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3603:          }
1.126     brouard  3604:        
1.226     brouard  3605:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3606:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3607:          savm=oldm;
                   3608:          oldm=newm;
                   3609:        } /* end mult */
                   3610:       
                   3611:        s1=s[mw[mi][i]][i];
                   3612:        s2=s[mw[mi+1][i]][i];
                   3613:        if( s2 > nlstate){ 
                   3614:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3615:        } else if  ( s2==-1 ) { /* alive */
                   3616:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3617:            survp += out[s1][j];
                   3618:          lli= log(survp);
                   3619:        }else{
                   3620:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3621:        }
                   3622:        ipmx +=1;
                   3623:        sw += weight[i];
                   3624:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3625: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3626:       } /* end of wave */
                   3627:     } /* end of individual */
                   3628:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3629:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3630:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3631:       for(mi=1; mi<= wav[i]-1; mi++){
                   3632:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3633:          for (j=1;j<=nlstate+ndeath;j++){
                   3634:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3635:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3636:          }
                   3637:        for(d=0; d<dh[mi][i]; d++){
                   3638:          newm=savm;
                   3639:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3640:          cov[2]=agexact;
                   3641:          if(nagesqr==1)
                   3642:            cov[3]= agexact*agexact;
                   3643:          for (kk=1; kk<=cptcovage;kk++) {
                   3644:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3645:          }
1.126     brouard  3646:        
1.226     brouard  3647:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3648:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3649:          savm=oldm;
                   3650:          oldm=newm;
                   3651:        } /* end mult */
                   3652:       
                   3653:        s1=s[mw[mi][i]][i];
                   3654:        s2=s[mw[mi+1][i]][i];
                   3655:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3656:        ipmx +=1;
                   3657:        sw += weight[i];
                   3658:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3659:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3660:       } /* end of wave */
                   3661:     } /* end of individual */
                   3662:   } /* End of if */
                   3663:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3664:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3665:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3666:   return -l;
1.126     brouard  3667: }
                   3668: 
                   3669: /*************** log-likelihood *************/
                   3670: double funcone( double *x)
                   3671: {
1.228     brouard  3672:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3673:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3674:   int ioffset=0;
1.131     brouard  3675:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3676:   double **out;
                   3677:   double lli; /* Individual log likelihood */
                   3678:   double llt;
                   3679:   int s1, s2;
1.228     brouard  3680:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3681: 
1.126     brouard  3682:   double bbh, survp;
1.187     brouard  3683:   double agexact;
1.214     brouard  3684:   double agebegin, ageend;
1.126     brouard  3685:   /*extern weight */
                   3686:   /* We are differentiating ll according to initial status */
                   3687:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3688:   /*for(i=1;i<imx;i++) 
                   3689:     printf(" %d\n",s[4][i]);
                   3690:   */
                   3691:   cov[1]=1.;
                   3692: 
                   3693:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3694:   ioffset=0;
                   3695:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3696:     /* ioffset=2+nagesqr+cptcovage; */
                   3697:     ioffset=2+nagesqr;
1.232     brouard  3698:     /* Fixed */
1.224     brouard  3699:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3700:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3701:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3702:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3703: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3704: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3705: /*    cov[2+6]=covar[2][i]; V2  */
                   3706: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3707: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3708: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3709: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3710: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3711: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3712:     }
1.232     brouard  3713:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3714:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3715:     /* } */
1.231     brouard  3716:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3717:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3718:     /* } */
1.225     brouard  3719:     
1.233     brouard  3720: 
                   3721:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3722:     /* Wave varying (but not age varying) */
                   3723:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3724:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3725:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3726:       }
1.232     brouard  3727:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3728:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3729:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3730:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3731:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3732:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3733:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3734:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3735:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3736:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3737:       /* } */
1.126     brouard  3738:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3739:        for (j=1;j<=nlstate+ndeath;j++){
                   3740:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3741:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3742:        }
1.214     brouard  3743:       
                   3744:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3745:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3746:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3747:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3748:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3749:          and mw[mi+1][i]. dh depends on stepm.*/
                   3750:        newm=savm;
1.247     brouard  3751:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3752:        cov[2]=agexact;
                   3753:        if(nagesqr==1)
                   3754:          cov[3]= agexact*agexact;
                   3755:        for (kk=1; kk<=cptcovage;kk++) {
                   3756:          if(!FixedV[Tvar[Tage[kk]]])
                   3757:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3758:          else
                   3759:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3760:        }
                   3761:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3762:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3763:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3764:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3765:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3766:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3767:        savm=oldm;
                   3768:        oldm=newm;
1.126     brouard  3769:       } /* end mult */
                   3770:       
                   3771:       s1=s[mw[mi][i]][i];
                   3772:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3773:       /* if(s2==-1){ */
1.268     brouard  3774:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3775:       /*       /\* exit(1); *\/ */
                   3776:       /* } */
1.126     brouard  3777:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3778:       /* bias is positive if real duration
                   3779:        * is higher than the multiple of stepm and negative otherwise.
                   3780:        */
                   3781:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3782:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3783:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3784:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3785:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3786:        lli= log(survp);
1.126     brouard  3787:       }else if (mle==1){
1.242     brouard  3788:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3789:       } else if(mle==2){
1.242     brouard  3790:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3791:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3792:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3793:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3794:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3795:       } else{  /* mle=0 back to 1 */
1.242     brouard  3796:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3797:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3798:       } /* End of if */
                   3799:       ipmx +=1;
                   3800:       sw += weight[i];
                   3801:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3802:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3803:       if(globpr){
1.246     brouard  3804:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3805:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3806:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3807:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3808:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3809:          llt +=ll[k]*gipmx/gsw;
                   3810:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3811:        }
                   3812:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3813:       }
1.232     brouard  3814:        } /* end of wave */
                   3815: } /* end of individual */
                   3816: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3817: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3818: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3819: if(globpr==0){ /* First time we count the contributions and weights */
                   3820:        gipmx=ipmx;
                   3821:        gsw=sw;
                   3822: }
                   3823: return -l;
1.126     brouard  3824: }
                   3825: 
                   3826: 
                   3827: /*************** function likelione ***********/
                   3828: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3829: {
                   3830:   /* This routine should help understanding what is done with 
                   3831:      the selection of individuals/waves and
                   3832:      to check the exact contribution to the likelihood.
                   3833:      Plotting could be done.
                   3834:    */
                   3835:   int k;
                   3836: 
                   3837:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3838:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3839:     strcat(fileresilk,fileresu);
1.126     brouard  3840:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3841:       printf("Problem with resultfile: %s\n", fileresilk);
                   3842:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3843:     }
1.214     brouard  3844:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3845:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3846:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3847:     for(k=1; k<=nlstate; k++) 
                   3848:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3849:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3850:   }
                   3851: 
                   3852:   *fretone=(*funcone)(p);
                   3853:   if(*globpri !=0){
                   3854:     fclose(ficresilk);
1.205     brouard  3855:     if (mle ==0)
                   3856:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3857:     else if(mle >=1)
                   3858:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3859:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3860:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3861:       
                   3862:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3863:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3864: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3865:     }
1.207     brouard  3866:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3867: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3868:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3869: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3870:     fflush(fichtm);
1.205     brouard  3871:   }
1.126     brouard  3872:   return;
                   3873: }
                   3874: 
                   3875: 
                   3876: /*********** Maximum Likelihood Estimation ***************/
                   3877: 
                   3878: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3879: {
1.165     brouard  3880:   int i,j, iter=0;
1.126     brouard  3881:   double **xi;
                   3882:   double fret;
                   3883:   double fretone; /* Only one call to likelihood */
                   3884:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3885: 
                   3886: #ifdef NLOPT
                   3887:   int creturn;
                   3888:   nlopt_opt opt;
                   3889:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3890:   double *lb;
                   3891:   double minf; /* the minimum objective value, upon return */
                   3892:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3893:   myfunc_data dinst, *d = &dinst;
                   3894: #endif
                   3895: 
                   3896: 
1.126     brouard  3897:   xi=matrix(1,npar,1,npar);
                   3898:   for (i=1;i<=npar;i++)
                   3899:     for (j=1;j<=npar;j++)
                   3900:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3901:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3902:   strcpy(filerespow,"POW_"); 
1.126     brouard  3903:   strcat(filerespow,fileres);
                   3904:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3905:     printf("Problem with resultfile: %s\n", filerespow);
                   3906:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3907:   }
                   3908:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3909:   for (i=1;i<=nlstate;i++)
                   3910:     for(j=1;j<=nlstate+ndeath;j++)
                   3911:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3912:   fprintf(ficrespow,"\n");
1.162     brouard  3913: #ifdef POWELL
1.126     brouard  3914:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3915: #endif
1.126     brouard  3916: 
1.162     brouard  3917: #ifdef NLOPT
                   3918: #ifdef NEWUOA
                   3919:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3920: #else
                   3921:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3922: #endif
                   3923:   lb=vector(0,npar-1);
                   3924:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3925:   nlopt_set_lower_bounds(opt, lb);
                   3926:   nlopt_set_initial_step1(opt, 0.1);
                   3927:   
                   3928:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3929:   d->function = func;
                   3930:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3931:   nlopt_set_min_objective(opt, myfunc, d);
                   3932:   nlopt_set_xtol_rel(opt, ftol);
                   3933:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3934:     printf("nlopt failed! %d\n",creturn); 
                   3935:   }
                   3936:   else {
                   3937:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3938:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3939:     iter=1; /* not equal */
                   3940:   }
                   3941:   nlopt_destroy(opt);
                   3942: #endif
1.126     brouard  3943:   free_matrix(xi,1,npar,1,npar);
                   3944:   fclose(ficrespow);
1.203     brouard  3945:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3946:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3947:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3948: 
                   3949: }
                   3950: 
                   3951: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3952: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3953: {
                   3954:   double  **a,**y,*x,pd;
1.203     brouard  3955:   /* double **hess; */
1.164     brouard  3956:   int i, j;
1.126     brouard  3957:   int *indx;
                   3958: 
                   3959:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3960:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3961:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3962:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3963:   double gompertz(double p[]);
1.203     brouard  3964:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3965: 
                   3966:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3967:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3968:   for (i=1;i<=npar;i++){
1.203     brouard  3969:     printf("%d-",i);fflush(stdout);
                   3970:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3971:    
                   3972:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3973:     
                   3974:     /*  printf(" %f ",p[i]);
                   3975:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3976:   }
                   3977:   
                   3978:   for (i=1;i<=npar;i++) {
                   3979:     for (j=1;j<=npar;j++)  {
                   3980:       if (j>i) { 
1.203     brouard  3981:        printf(".%d-%d",i,j);fflush(stdout);
                   3982:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3983:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3984:        
                   3985:        hess[j][i]=hess[i][j];    
                   3986:        /*printf(" %lf ",hess[i][j]);*/
                   3987:       }
                   3988:     }
                   3989:   }
                   3990:   printf("\n");
                   3991:   fprintf(ficlog,"\n");
                   3992: 
                   3993:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3994:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3995:   
                   3996:   a=matrix(1,npar,1,npar);
                   3997:   y=matrix(1,npar,1,npar);
                   3998:   x=vector(1,npar);
                   3999:   indx=ivector(1,npar);
                   4000:   for (i=1;i<=npar;i++)
                   4001:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4002:   ludcmp(a,npar,indx,&pd);
                   4003: 
                   4004:   for (j=1;j<=npar;j++) {
                   4005:     for (i=1;i<=npar;i++) x[i]=0;
                   4006:     x[j]=1;
                   4007:     lubksb(a,npar,indx,x);
                   4008:     for (i=1;i<=npar;i++){ 
                   4009:       matcov[i][j]=x[i];
                   4010:     }
                   4011:   }
                   4012: 
                   4013:   printf("\n#Hessian matrix#\n");
                   4014:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4015:   for (i=1;i<=npar;i++) { 
                   4016:     for (j=1;j<=npar;j++) { 
1.203     brouard  4017:       printf("%.6e ",hess[i][j]);
                   4018:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4019:     }
                   4020:     printf("\n");
                   4021:     fprintf(ficlog,"\n");
                   4022:   }
                   4023: 
1.203     brouard  4024:   /* printf("\n#Covariance matrix#\n"); */
                   4025:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4026:   /* for (i=1;i<=npar;i++) {  */
                   4027:   /*   for (j=1;j<=npar;j++) {  */
                   4028:   /*     printf("%.6e ",matcov[i][j]); */
                   4029:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4030:   /*   } */
                   4031:   /*   printf("\n"); */
                   4032:   /*   fprintf(ficlog,"\n"); */
                   4033:   /* } */
                   4034: 
1.126     brouard  4035:   /* Recompute Inverse */
1.203     brouard  4036:   /* for (i=1;i<=npar;i++) */
                   4037:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4038:   /* ludcmp(a,npar,indx,&pd); */
                   4039: 
                   4040:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4041: 
                   4042:   /* for (j=1;j<=npar;j++) { */
                   4043:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4044:   /*   x[j]=1; */
                   4045:   /*   lubksb(a,npar,indx,x); */
                   4046:   /*   for (i=1;i<=npar;i++){  */
                   4047:   /*     y[i][j]=x[i]; */
                   4048:   /*     printf("%.3e ",y[i][j]); */
                   4049:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4050:   /*   } */
                   4051:   /*   printf("\n"); */
                   4052:   /*   fprintf(ficlog,"\n"); */
                   4053:   /* } */
                   4054: 
                   4055:   /* Verifying the inverse matrix */
                   4056: #ifdef DEBUGHESS
                   4057:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4058: 
1.203     brouard  4059:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4060:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4061: 
                   4062:   for (j=1;j<=npar;j++) {
                   4063:     for (i=1;i<=npar;i++){ 
1.203     brouard  4064:       printf("%.2f ",y[i][j]);
                   4065:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4066:     }
                   4067:     printf("\n");
                   4068:     fprintf(ficlog,"\n");
                   4069:   }
1.203     brouard  4070: #endif
1.126     brouard  4071: 
                   4072:   free_matrix(a,1,npar,1,npar);
                   4073:   free_matrix(y,1,npar,1,npar);
                   4074:   free_vector(x,1,npar);
                   4075:   free_ivector(indx,1,npar);
1.203     brouard  4076:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4077: 
                   4078: 
                   4079: }
                   4080: 
                   4081: /*************** hessian matrix ****************/
                   4082: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4083: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4084:   int i;
                   4085:   int l=1, lmax=20;
1.203     brouard  4086:   double k1,k2, res, fx;
1.132     brouard  4087:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4088:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4089:   int k=0,kmax=10;
                   4090:   double l1;
                   4091: 
                   4092:   fx=func(x);
                   4093:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4094:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4095:     l1=pow(10,l);
                   4096:     delts=delt;
                   4097:     for(k=1 ; k <kmax; k=k+1){
                   4098:       delt = delta*(l1*k);
                   4099:       p2[theta]=x[theta] +delt;
1.145     brouard  4100:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4101:       p2[theta]=x[theta]-delt;
                   4102:       k2=func(p2)-fx;
                   4103:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4104:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4105:       
1.203     brouard  4106: #ifdef DEBUGHESSII
1.126     brouard  4107:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4108:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4109: #endif
                   4110:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4111:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4112:        k=kmax;
                   4113:       }
                   4114:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4115:        k=kmax; l=lmax*10;
1.126     brouard  4116:       }
                   4117:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4118:        delts=delt;
                   4119:       }
1.203     brouard  4120:     } /* End loop k */
1.126     brouard  4121:   }
                   4122:   delti[theta]=delts;
                   4123:   return res; 
                   4124:   
                   4125: }
                   4126: 
1.203     brouard  4127: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4128: {
                   4129:   int i;
1.164     brouard  4130:   int l=1, lmax=20;
1.126     brouard  4131:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4132:   double p2[MAXPARM+1];
1.203     brouard  4133:   int k, kmax=1;
                   4134:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4135: 
                   4136:   int firstime=0;
1.203     brouard  4137:   
1.126     brouard  4138:   fx=func(x);
1.203     brouard  4139:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4140:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4141:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4142:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4143:     k1=func(p2)-fx;
                   4144:   
1.203     brouard  4145:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4146:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4147:     k2=func(p2)-fx;
                   4148:   
1.203     brouard  4149:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4150:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4151:     k3=func(p2)-fx;
                   4152:   
1.203     brouard  4153:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4154:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4155:     k4=func(p2)-fx;
1.203     brouard  4156:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4157:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4158:       firstime=1;
1.203     brouard  4159:       kmax=kmax+10;
1.208     brouard  4160:     }
                   4161:     if(kmax >=10 || firstime ==1){
1.246     brouard  4162:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4163:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4164:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4165:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4166:     }
                   4167: #ifdef DEBUGHESSIJ
                   4168:     v1=hess[thetai][thetai];
                   4169:     v2=hess[thetaj][thetaj];
                   4170:     cv12=res;
                   4171:     /* Computing eigen value of Hessian matrix */
                   4172:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4173:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4174:     if ((lc2 <0) || (lc1 <0) ){
                   4175:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4176:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4177:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4178:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4179:     }
1.126     brouard  4180: #endif
                   4181:   }
                   4182:   return res;
                   4183: }
                   4184: 
1.203     brouard  4185:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4186: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4187: /* { */
                   4188: /*   int i; */
                   4189: /*   int l=1, lmax=20; */
                   4190: /*   double k1,k2,k3,k4,res,fx; */
                   4191: /*   double p2[MAXPARM+1]; */
                   4192: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4193: /*   int k=0,kmax=10; */
                   4194: /*   double l1; */
                   4195:   
                   4196: /*   fx=func(x); */
                   4197: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4198: /*     l1=pow(10,l); */
                   4199: /*     delts=delt; */
                   4200: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4201: /*       delt = delti*(l1*k); */
                   4202: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4203: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4204: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4205: /*       k1=func(p2)-fx; */
                   4206:       
                   4207: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4208: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4209: /*       k2=func(p2)-fx; */
                   4210:       
                   4211: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4212: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4213: /*       k3=func(p2)-fx; */
                   4214:       
                   4215: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4216: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4217: /*       k4=func(p2)-fx; */
                   4218: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4219: /* #ifdef DEBUGHESSIJ */
                   4220: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4221: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4222: /* #endif */
                   4223: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4224: /*     k=kmax; */
                   4225: /*       } */
                   4226: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4227: /*     k=kmax; l=lmax*10; */
                   4228: /*       } */
                   4229: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4230: /*     delts=delt; */
                   4231: /*       } */
                   4232: /*     } /\* End loop k *\/ */
                   4233: /*   } */
                   4234: /*   delti[theta]=delts; */
                   4235: /*   return res;  */
                   4236: /* } */
                   4237: 
                   4238: 
1.126     brouard  4239: /************** Inverse of matrix **************/
                   4240: void ludcmp(double **a, int n, int *indx, double *d) 
                   4241: { 
                   4242:   int i,imax,j,k; 
                   4243:   double big,dum,sum,temp; 
                   4244:   double *vv; 
                   4245:  
                   4246:   vv=vector(1,n); 
                   4247:   *d=1.0; 
                   4248:   for (i=1;i<=n;i++) { 
                   4249:     big=0.0; 
                   4250:     for (j=1;j<=n;j++) 
                   4251:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4252:     if (big == 0.0){
                   4253:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4254:       for (j=1;j<=n;j++) {
                   4255:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4256:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4257:       }
                   4258:       fflush(ficlog);
                   4259:       fclose(ficlog);
                   4260:       nrerror("Singular matrix in routine ludcmp"); 
                   4261:     }
1.126     brouard  4262:     vv[i]=1.0/big; 
                   4263:   } 
                   4264:   for (j=1;j<=n;j++) { 
                   4265:     for (i=1;i<j;i++) { 
                   4266:       sum=a[i][j]; 
                   4267:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4268:       a[i][j]=sum; 
                   4269:     } 
                   4270:     big=0.0; 
                   4271:     for (i=j;i<=n;i++) { 
                   4272:       sum=a[i][j]; 
                   4273:       for (k=1;k<j;k++) 
                   4274:        sum -= a[i][k]*a[k][j]; 
                   4275:       a[i][j]=sum; 
                   4276:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4277:        big=dum; 
                   4278:        imax=i; 
                   4279:       } 
                   4280:     } 
                   4281:     if (j != imax) { 
                   4282:       for (k=1;k<=n;k++) { 
                   4283:        dum=a[imax][k]; 
                   4284:        a[imax][k]=a[j][k]; 
                   4285:        a[j][k]=dum; 
                   4286:       } 
                   4287:       *d = -(*d); 
                   4288:       vv[imax]=vv[j]; 
                   4289:     } 
                   4290:     indx[j]=imax; 
                   4291:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4292:     if (j != n) { 
                   4293:       dum=1.0/(a[j][j]); 
                   4294:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4295:     } 
                   4296:   } 
                   4297:   free_vector(vv,1,n);  /* Doesn't work */
                   4298: ;
                   4299: } 
                   4300: 
                   4301: void lubksb(double **a, int n, int *indx, double b[]) 
                   4302: { 
                   4303:   int i,ii=0,ip,j; 
                   4304:   double sum; 
                   4305:  
                   4306:   for (i=1;i<=n;i++) { 
                   4307:     ip=indx[i]; 
                   4308:     sum=b[ip]; 
                   4309:     b[ip]=b[i]; 
                   4310:     if (ii) 
                   4311:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4312:     else if (sum) ii=i; 
                   4313:     b[i]=sum; 
                   4314:   } 
                   4315:   for (i=n;i>=1;i--) { 
                   4316:     sum=b[i]; 
                   4317:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4318:     b[i]=sum/a[i][i]; 
                   4319:   } 
                   4320: } 
                   4321: 
                   4322: void pstamp(FILE *fichier)
                   4323: {
1.196     brouard  4324:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4325: }
                   4326: 
1.253     brouard  4327: 
                   4328: 
1.126     brouard  4329: /************ Frequencies ********************/
1.251     brouard  4330: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4331:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4332:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4333: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4334:   
1.265     brouard  4335:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4336:   int iind=0, iage=0;
                   4337:   int mi; /* Effective wave */
                   4338:   int first;
                   4339:   double ***freq; /* Frequencies */
1.268     brouard  4340:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4341:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4342:   double *meanq;
                   4343:   double **meanqt;
                   4344:   double *pp, **prop, *posprop, *pospropt;
                   4345:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4346:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4347:   double agebegin, ageend;
                   4348:     
                   4349:   pp=vector(1,nlstate);
1.251     brouard  4350:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4351:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4352:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4353:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4354:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4355:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4356:   strcpy(fileresp,"P_");
                   4357:   strcat(fileresp,fileresu);
                   4358:   /*strcat(fileresphtm,fileresu);*/
                   4359:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4360:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4361:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4362:     exit(0);
                   4363:   }
1.240     brouard  4364:   
1.226     brouard  4365:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4366:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4367:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4368:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4369:     fflush(ficlog);
                   4370:     exit(70); 
                   4371:   }
                   4372:   else{
                   4373:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4374: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4375: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4376:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4377:   }
1.237     brouard  4378:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4379:   
1.226     brouard  4380:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4381:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4382:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4383:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4384:     fflush(ficlog);
                   4385:     exit(70); 
1.240     brouard  4386:   } else{
1.226     brouard  4387:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4388: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4389: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4390:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4391:   }
1.240     brouard  4392:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4393:   
1.253     brouard  4394:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4395:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4396:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4397:   j1=0;
1.126     brouard  4398:   
1.227     brouard  4399:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4400:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4401:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4402:   
                   4403:   
1.226     brouard  4404:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4405:      reference=low_education V1=0,V2=0
                   4406:      med_educ                V1=1 V2=0, 
                   4407:      high_educ               V1=0 V2=1
                   4408:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4409:   */
1.249     brouard  4410:   dateintsum=0;
                   4411:   k2cpt=0;
                   4412: 
1.253     brouard  4413:   if(cptcoveff == 0 )
1.265     brouard  4414:     nl=1;  /* Constant and age model only */
1.253     brouard  4415:   else
                   4416:     nl=2;
1.265     brouard  4417: 
                   4418:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4419:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4420:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4421:    *     freq[s1][s2][iage] =0.
                   4422:    *     Loop on iind
                   4423:    *       ++freq[s1][s2][iage] weighted
                   4424:    *     end iind
                   4425:    *     if covariate and j!0
                   4426:    *       headers Variable on one line
                   4427:    *     endif cov j!=0
                   4428:    *     header of frequency table by age
                   4429:    *     Loop on age
                   4430:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4431:    *       pos+=freq[s1][s2][iage] weighted
                   4432:    *       Loop on s1 initial state
                   4433:    *         fprintf(ficresp
                   4434:    *       end s1
                   4435:    *     end age
                   4436:    *     if j!=0 computes starting values
                   4437:    *     end compute starting values
                   4438:    *   end j1
                   4439:    * end nl 
                   4440:    */
1.253     brouard  4441:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4442:     if(nj==1)
                   4443:       j=0;  /* First pass for the constant */
1.265     brouard  4444:     else{
1.253     brouard  4445:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4446:     }
1.251     brouard  4447:     first=1;
1.265     brouard  4448:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4449:       posproptt=0.;
                   4450:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4451:        scanf("%d", i);*/
                   4452:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4453:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4454:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4455:            freq[i][s2][m]=0;
1.251     brouard  4456:       
                   4457:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4458:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4459:          prop[i][m]=0;
                   4460:        posprop[i]=0;
                   4461:        pospropt[i]=0;
                   4462:       }
                   4463:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4464:       /*   meanq[z1]+=0.; */
                   4465:       /*   for(m=1;m<=lastpass;m++){ */
                   4466:       /*       meanqt[m][z1]=0.; */
                   4467:       /*   } */
                   4468:       /* } */
                   4469:       
                   4470:       /* dateintsum=0; */
                   4471:       /* k2cpt=0; */
                   4472:       
1.265     brouard  4473:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4474:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4475:        bool=1;
                   4476:        if(j !=0){
                   4477:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4478:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4479:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4480:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4481:              /* } */
                   4482:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4483:                /* if(Tvaraff[z1] ==-20){ */
                   4484:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4485:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4486:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4487:                /* }else  */
                   4488:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4489:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4490:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4491:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4492:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4493:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4494:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4495:                } /* Onlyf fixed */
                   4496:              } /* end z1 */
                   4497:            } /* cptcovn > 0 */
                   4498:          } /* end any */
                   4499:        }/* end j==0 */
1.265     brouard  4500:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4501:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4502:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4503:            m=mw[mi][iind];
                   4504:            if(j!=0){
                   4505:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4506:                for (z1=1; z1<=cptcoveff; z1++) {
                   4507:                  if( Fixed[Tmodelind[z1]]==1){
                   4508:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4509:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4510:                                                                                      value is -1, we don't select. It differs from the 
                   4511:                                                                                      constant and age model which counts them. */
                   4512:                      bool=0; /* not selected */
                   4513:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4514:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4515:                      bool=0;
                   4516:                    }
                   4517:                  }
                   4518:                }
                   4519:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4520:            } /* end j==0 */
                   4521:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4522:            if(bool==1){
                   4523:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4524:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4525:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4526:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4527:              if(m >=firstpass && m <=lastpass){
                   4528:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4529:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4530:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4531:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4532:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4533:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4534:                if (m<lastpass) {
                   4535:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4536:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4537:                  if(s[m][iind]==-1)
                   4538:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4539:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4540:                  /* if((int)agev[m][iind] == 55) */
                   4541:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4542:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4543:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4544:                }
1.251     brouard  4545:              } /* end if between passes */  
                   4546:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4547:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4548:                k2cpt++;
                   4549:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4550:              }
1.251     brouard  4551:            }else{
                   4552:              bool=1;
                   4553:            }/* end bool 2 */
                   4554:          } /* end m */
                   4555:        } /* end bool */
                   4556:       } /* end iind = 1 to imx */
                   4557:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4558:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4559:       
                   4560:       
                   4561:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4562:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4563:         pstamp(ficresp);
1.251     brouard  4564:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4565:         pstamp(ficresp);
1.251     brouard  4566:        printf( "\n#********** Variable "); 
                   4567:        fprintf(ficresp, "\n#********** Variable "); 
                   4568:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4569:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4570:        fprintf(ficlog, "\n#********** Variable "); 
                   4571:        for (z1=1; z1<=cptcoveff; z1++){
                   4572:          if(!FixedV[Tvaraff[z1]]){
                   4573:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4574:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4575:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4576:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4577:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4578:          }else{
1.251     brouard  4579:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4580:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4581:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4582:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4583:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4584:          }
                   4585:        }
                   4586:        printf( "**********\n#");
                   4587:        fprintf(ficresp, "**********\n#");
                   4588:        fprintf(ficresphtm, "**********</h3>\n");
                   4589:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4590:        fprintf(ficlog, "**********\n");
                   4591:       }
                   4592:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4593:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4594:         fprintf(ficresp, " Age");
                   4595:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4596:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4597:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4598:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4599:       }
1.265     brouard  4600:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4601:       fprintf(ficresphtm, "\n");
                   4602:       
                   4603:       /* Header of frequency table by age */
                   4604:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4605:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4606:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4607:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4608:          if(s2!=0 && m!=0)
                   4609:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4610:        }
1.226     brouard  4611:       }
1.251     brouard  4612:       fprintf(ficresphtmfr, "\n");
                   4613:     
                   4614:       /* For each age */
                   4615:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4616:        fprintf(ficresphtm,"<tr>");
                   4617:        if(iage==iagemax+1){
                   4618:          fprintf(ficlog,"1");
                   4619:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4620:        }else if(iage==iagemax+2){
                   4621:          fprintf(ficlog,"0");
                   4622:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4623:        }else if(iage==iagemax+3){
                   4624:          fprintf(ficlog,"Total");
                   4625:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4626:        }else{
1.240     brouard  4627:          if(first==1){
1.251     brouard  4628:            first=0;
                   4629:            printf("See log file for details...\n");
                   4630:          }
                   4631:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4632:          fprintf(ficlog,"Age %d", iage);
                   4633:        }
1.265     brouard  4634:        for(s1=1; s1 <=nlstate ; s1++){
                   4635:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4636:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4637:        }
1.265     brouard  4638:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4639:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4640:            pos += freq[s1][m][iage];
                   4641:          if(pp[s1]>=1.e-10){
1.251     brouard  4642:            if(first==1){
1.265     brouard  4643:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4644:            }
1.265     brouard  4645:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4646:          }else{
                   4647:            if(first==1)
1.265     brouard  4648:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4649:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4650:          }
                   4651:        }
                   4652:       
1.265     brouard  4653:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4654:          /* posprop[s1]=0; */
                   4655:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4656:            pp[s1] += freq[s1][m][iage];
                   4657:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4658:       
                   4659:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4660:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4661:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4662:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4663:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4664:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4665:        }
                   4666:        
                   4667:        /* Writing ficresp */
                   4668:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4669:           if( iage <= iagemax){
                   4670:            fprintf(ficresp," %d",iage);
                   4671:           }
                   4672:         }else if( nj==2){
                   4673:           if( iage <= iagemax){
                   4674:            fprintf(ficresp," %d",iage);
                   4675:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4676:           }
1.240     brouard  4677:        }
1.265     brouard  4678:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4679:          if(pos>=1.e-5){
1.251     brouard  4680:            if(first==1)
1.265     brouard  4681:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4682:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4683:          }else{
                   4684:            if(first==1)
1.265     brouard  4685:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4686:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4687:          }
                   4688:          if( iage <= iagemax){
                   4689:            if(pos>=1.e-5){
1.265     brouard  4690:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4691:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4692:               }else if( nj==2){
                   4693:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4694:               }
                   4695:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4696:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4697:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4698:            } else{
                   4699:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4700:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4701:            }
1.240     brouard  4702:          }
1.265     brouard  4703:          pospropt[s1] +=posprop[s1];
                   4704:        } /* end loop s1 */
1.251     brouard  4705:        /* pospropt=0.; */
1.265     brouard  4706:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4707:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4708:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4709:              if(first==1){
1.265     brouard  4710:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4711:              }
1.265     brouard  4712:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4713:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4714:            }
1.265     brouard  4715:            if(s1!=0 && m!=0)
                   4716:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4717:          }
1.265     brouard  4718:        } /* end loop s1 */
1.251     brouard  4719:        posproptt=0.; 
1.265     brouard  4720:        for(s1=1; s1 <=nlstate; s1++){
                   4721:          posproptt += pospropt[s1];
1.251     brouard  4722:        }
                   4723:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4724:        fprintf(ficresphtm,"</tr>\n");
                   4725:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4726:          if(iage <= iagemax)
                   4727:            fprintf(ficresp,"\n");
1.240     brouard  4728:        }
1.251     brouard  4729:        if(first==1)
                   4730:          printf("Others in log...\n");
                   4731:        fprintf(ficlog,"\n");
                   4732:       } /* end loop age iage */
1.265     brouard  4733:       
1.251     brouard  4734:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4735:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4736:        if(posproptt < 1.e-5){
1.265     brouard  4737:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4738:        }else{
1.265     brouard  4739:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4740:        }
1.226     brouard  4741:       }
1.251     brouard  4742:       fprintf(ficresphtm,"</tr>\n");
                   4743:       fprintf(ficresphtm,"</table>\n");
                   4744:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4745:       if(posproptt < 1.e-5){
1.251     brouard  4746:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4747:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4748:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4749:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4750:        invalidvarcomb[j1]=1;
1.226     brouard  4751:       }else{
1.251     brouard  4752:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4753:        invalidvarcomb[j1]=0;
1.226     brouard  4754:       }
1.251     brouard  4755:       fprintf(ficresphtmfr,"</table>\n");
                   4756:       fprintf(ficlog,"\n");
                   4757:       if(j!=0){
                   4758:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4759:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4760:          for(k=1; k <=(nlstate+ndeath); k++){
                   4761:            if (k != i) {
1.265     brouard  4762:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4763:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4764:                  if(j1==1){ /* All dummy covariates to zero */
                   4765:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4766:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4767:                    printf("%d%d ",i,k);
                   4768:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4769:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4770:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4771:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4772:                  }
1.253     brouard  4773:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4774:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4775:                    x[iage]= (double)iage;
                   4776:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4777:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4778:                  }
1.268     brouard  4779:                  /* Some are not finite, but linreg will ignore these ages */
                   4780:                  no=0;
1.253     brouard  4781:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4782:                  pstart[s1]=b;
                   4783:                  pstart[s1-1]=a;
1.252     brouard  4784:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4785:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4786:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4787:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4788:                  printf("%d%d ",i,k);
                   4789:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4790:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4791:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4792:                  ;
                   4793:                }
                   4794:                /* printf("%12.7f )", param[i][jj][k]); */
                   4795:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4796:                s1++; 
1.251     brouard  4797:              } /* end jj */
                   4798:            } /* end k!= i */
                   4799:          } /* end k */
1.265     brouard  4800:        } /* end i, s1 */
1.251     brouard  4801:       } /* end j !=0 */
                   4802:     } /* end selected combination of covariate j1 */
                   4803:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4804:       printf("#Freqsummary: Starting values for the constants:\n");
                   4805:       fprintf(ficlog,"\n");
1.265     brouard  4806:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4807:        for(k=1; k <=(nlstate+ndeath); k++){
                   4808:          if (k != i) {
                   4809:            printf("%d%d ",i,k);
                   4810:            fprintf(ficlog,"%d%d ",i,k);
                   4811:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4812:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4813:              if(jj==1){ /* Age has to be done */
1.265     brouard  4814:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4815:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4816:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4817:              }
                   4818:              /* printf("%12.7f )", param[i][jj][k]); */
                   4819:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4820:              s1++; 
1.250     brouard  4821:            }
1.251     brouard  4822:            printf("\n");
                   4823:            fprintf(ficlog,"\n");
1.250     brouard  4824:          }
                   4825:        }
                   4826:       }
1.251     brouard  4827:       printf("#Freqsummary\n");
                   4828:       fprintf(ficlog,"\n");
1.265     brouard  4829:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4830:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4831:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4832:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4833:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4834:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4835:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4836:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4837:          /* } */
                   4838:        }
1.265     brouard  4839:       } /* end loop s1 */
1.251     brouard  4840:       
                   4841:       printf("\n");
                   4842:       fprintf(ficlog,"\n");
                   4843:     } /* end j=0 */
1.249     brouard  4844:   } /* end j */
1.252     brouard  4845: 
1.253     brouard  4846:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4847:     for(i=1, jk=1; i <=nlstate; i++){
                   4848:       for(j=1; j <=nlstate+ndeath; j++){
                   4849:        if(j!=i){
                   4850:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4851:          printf("%1d%1d",i,j);
                   4852:          fprintf(ficparo,"%1d%1d",i,j);
                   4853:          for(k=1; k<=ncovmodel;k++){
                   4854:            /*    printf(" %lf",param[i][j][k]); */
                   4855:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4856:            p[jk]=pstart[jk];
                   4857:            printf(" %f ",pstart[jk]);
                   4858:            fprintf(ficparo," %f ",pstart[jk]);
                   4859:            jk++;
                   4860:          }
                   4861:          printf("\n");
                   4862:          fprintf(ficparo,"\n");
                   4863:        }
                   4864:       }
                   4865:     }
                   4866:   } /* end mle=-2 */
1.226     brouard  4867:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4868:   
1.226     brouard  4869:   fclose(ficresp);
                   4870:   fclose(ficresphtm);
                   4871:   fclose(ficresphtmfr);
                   4872:   free_vector(meanq,1,nqfveff);
                   4873:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4874:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4875:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4876:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4877:   free_vector(pospropt,1,nlstate);
                   4878:   free_vector(posprop,1,nlstate);
1.251     brouard  4879:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4880:   free_vector(pp,1,nlstate);
                   4881:   /* End of freqsummary */
                   4882: }
1.126     brouard  4883: 
1.268     brouard  4884: /* Simple linear regression */
                   4885: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4886: 
                   4887:   /* y=a+bx regression */
                   4888:   double   sumx = 0.0;                        /* sum of x                      */
                   4889:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4890:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4891:   double   sumy = 0.0;                        /* sum of y                      */
                   4892:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4893:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4894:   double yhat;
                   4895:   
                   4896:   double denom=0;
                   4897:   int i;
                   4898:   int ne=*no;
                   4899:   
                   4900:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4901:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4902:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4903:       continue;
                   4904:     }
                   4905:     ne=ne+1;
                   4906:     sumx  += x[i];       
                   4907:     sumx2 += x[i]*x[i];  
                   4908:     sumxy += x[i] * y[i];
                   4909:     sumy  += y[i];      
                   4910:     sumy2 += y[i]*y[i]; 
                   4911:     denom = (ne * sumx2 - sumx*sumx);
                   4912:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4913:   } 
                   4914:   
                   4915:   denom = (ne * sumx2 - sumx*sumx);
                   4916:   if (denom == 0) {
                   4917:     // vertical, slope m is infinity
                   4918:     *b = INFINITY;
                   4919:     *a = 0;
                   4920:     if (r) *r = 0;
                   4921:     return 1;
                   4922:   }
                   4923:   
                   4924:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4925:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4926:   if (r!=NULL) {
                   4927:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4928:       sqrt((sumx2 - sumx*sumx/ne) *
                   4929:           (sumy2 - sumy*sumy/ne));
                   4930:   }
                   4931:   *no=ne;
                   4932:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4933:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4934:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4935:       continue;
                   4936:     }
                   4937:     ne=ne+1;
                   4938:     yhat = y[i] - *a -*b* x[i];
                   4939:     sume2  += yhat * yhat ;       
                   4940:     
                   4941:     denom = (ne * sumx2 - sumx*sumx);
                   4942:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4943:   } 
                   4944:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4945:   *sa= *sb * sqrt(sumx2/ne);
                   4946:   
                   4947:   return 0; 
                   4948: }
                   4949: 
1.126     brouard  4950: /************ Prevalence ********************/
1.227     brouard  4951: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4952: {  
                   4953:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4954:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4955:      We still use firstpass and lastpass as another selection.
                   4956:   */
1.126     brouard  4957:  
1.227     brouard  4958:   int i, m, jk, j1, bool, z1,j, iv;
                   4959:   int mi; /* Effective wave */
                   4960:   int iage;
                   4961:   double agebegin, ageend;
                   4962: 
                   4963:   double **prop;
                   4964:   double posprop; 
                   4965:   double  y2; /* in fractional years */
                   4966:   int iagemin, iagemax;
                   4967:   int first; /** to stop verbosity which is redirected to log file */
                   4968: 
                   4969:   iagemin= (int) agemin;
                   4970:   iagemax= (int) agemax;
                   4971:   /*pp=vector(1,nlstate);*/
1.251     brouard  4972:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4973:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4974:   j1=0;
1.222     brouard  4975:   
1.227     brouard  4976:   /*j=cptcoveff;*/
                   4977:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4978:   
1.227     brouard  4979:   first=1;
                   4980:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4981:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4982:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4983:        prop[i][iage]=0.0;
                   4984:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4985:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4986:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4987:     
                   4988:     for (i=1; i<=imx; i++) { /* Each individual */
                   4989:       bool=1;
                   4990:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4991:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4992:        m=mw[mi][i];
                   4993:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4994:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4995:        for (z1=1; z1<=cptcoveff; z1++){
                   4996:          if( Fixed[Tmodelind[z1]]==1){
                   4997:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4998:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4999:              bool=0;
                   5000:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5001:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5002:              bool=0;
                   5003:            }
                   5004:        }
                   5005:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5006:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5007:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5008:          if(m >=firstpass && m <=lastpass){
                   5009:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5010:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5011:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5012:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5013:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5014:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5015:                exit(1);
                   5016:              }
                   5017:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5018:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5019:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5020:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5021:              } /* end valid statuses */ 
                   5022:            } /* end selection of dates */
                   5023:          } /* end selection of waves */
                   5024:        } /* end bool */
                   5025:       } /* end wave */
                   5026:     } /* end individual */
                   5027:     for(i=iagemin; i <= iagemax+3; i++){  
                   5028:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5029:        posprop += prop[jk][i]; 
                   5030:       } 
                   5031:       
                   5032:       for(jk=1; jk <=nlstate ; jk++){      
                   5033:        if( i <=  iagemax){ 
                   5034:          if(posprop>=1.e-5){ 
                   5035:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5036:          } else{
                   5037:            if(first==1){
                   5038:              first=0;
1.266     brouard  5039:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5040:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5041:            }else{
                   5042:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5043:            }
                   5044:          }
                   5045:        } 
                   5046:       }/* end jk */ 
                   5047:     }/* end i */ 
1.222     brouard  5048:      /*} *//* end i1 */
1.227     brouard  5049:   } /* end j1 */
1.222     brouard  5050:   
1.227     brouard  5051:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5052:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5053:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5054: }  /* End of prevalence */
1.126     brouard  5055: 
                   5056: /************* Waves Concatenation ***************/
                   5057: 
                   5058: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5059: {
                   5060:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5061:      Death is a valid wave (if date is known).
                   5062:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5063:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5064:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5065:   */
1.126     brouard  5066: 
1.224     brouard  5067:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5068:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5069:      double sum=0., jmean=0.;*/
1.224     brouard  5070:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5071:   int j, k=0,jk, ju, jl;
                   5072:   double sum=0.;
                   5073:   first=0;
1.214     brouard  5074:   firstwo=0;
1.217     brouard  5075:   firsthree=0;
1.218     brouard  5076:   firstfour=0;
1.164     brouard  5077:   jmin=100000;
1.126     brouard  5078:   jmax=-1;
                   5079:   jmean=0.;
1.224     brouard  5080: 
                   5081: /* Treating live states */
1.214     brouard  5082:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5083:     mi=0;  /* First valid wave */
1.227     brouard  5084:     mli=0; /* Last valid wave */
1.126     brouard  5085:     m=firstpass;
1.214     brouard  5086:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5087:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5088:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5089:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5090:        mw[++mi][i]=m;
                   5091:        mli=m;
1.224     brouard  5092:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5093:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5094:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5095:       }
1.227     brouard  5096:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5097: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5098:        break;
1.224     brouard  5099: #else
1.227     brouard  5100:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5101:          if(firsthree == 0){
1.262     brouard  5102:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5103:            firsthree=1;
                   5104:          }
1.262     brouard  5105:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5106:          mw[++mi][i]=m;
                   5107:          mli=m;
                   5108:        }
                   5109:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5110:          nbwarn++;
                   5111:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5112:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5113:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5114:          }
                   5115:          break;
                   5116:        }
                   5117:        break;
1.224     brouard  5118: #endif
1.227     brouard  5119:       }/* End m >= lastpass */
1.126     brouard  5120:     }/* end while */
1.224     brouard  5121: 
1.227     brouard  5122:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5123:     /* After last pass */
1.224     brouard  5124: /* Treating death states */
1.214     brouard  5125:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5126:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5127:       /* } */
1.126     brouard  5128:       mi++;    /* Death is another wave */
                   5129:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5130:       /* Only death is a correct wave */
1.126     brouard  5131:       mw[mi][i]=m;
1.257     brouard  5132:     } /* else not in a death state */
1.224     brouard  5133: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5134:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5135:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5136:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5137:          nbwarn++;
                   5138:          if(firstfiv==0){
                   5139:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5140:            firstfiv=1;
                   5141:          }else{
                   5142:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5143:          }
                   5144:        }else{ /* Death occured afer last wave potential bias */
                   5145:          nberr++;
                   5146:          if(firstwo==0){
1.257     brouard  5147:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5148:            firstwo=1;
                   5149:          }
1.257     brouard  5150:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5151:        }
1.257     brouard  5152:       }else{ /* if date of interview is unknown */
1.227     brouard  5153:        /* death is known but not confirmed by death status at any wave */
                   5154:        if(firstfour==0){
                   5155:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5156:          firstfour=1;
                   5157:        }
                   5158:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5159:       }
1.224     brouard  5160:     } /* end if date of death is known */
                   5161: #endif
                   5162:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5163:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5164:     if(mi==0){
                   5165:       nbwarn++;
                   5166:       if(first==0){
1.227     brouard  5167:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5168:        first=1;
1.126     brouard  5169:       }
                   5170:       if(first==1){
1.227     brouard  5171:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5172:       }
                   5173:     } /* end mi==0 */
                   5174:   } /* End individuals */
1.214     brouard  5175:   /* wav and mw are no more changed */
1.223     brouard  5176:        
1.214     brouard  5177:   
1.126     brouard  5178:   for(i=1; i<=imx; i++){
                   5179:     for(mi=1; mi<wav[i];mi++){
                   5180:       if (stepm <=0)
1.227     brouard  5181:        dh[mi][i]=1;
1.126     brouard  5182:       else{
1.260     brouard  5183:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5184:          if (agedc[i] < 2*AGESUP) {
                   5185:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5186:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5187:            else if(j<0){
                   5188:              nberr++;
                   5189:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5190:              j=1; /* Temporary Dangerous patch */
                   5191:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5192:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5193:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5194:            }
                   5195:            k=k+1;
                   5196:            if (j >= jmax){
                   5197:              jmax=j;
                   5198:              ijmax=i;
                   5199:            }
                   5200:            if (j <= jmin){
                   5201:              jmin=j;
                   5202:              ijmin=i;
                   5203:            }
                   5204:            sum=sum+j;
                   5205:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5206:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5207:          }
                   5208:        }
                   5209:        else{
                   5210:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5211: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5212:                                        
1.227     brouard  5213:          k=k+1;
                   5214:          if (j >= jmax) {
                   5215:            jmax=j;
                   5216:            ijmax=i;
                   5217:          }
                   5218:          else if (j <= jmin){
                   5219:            jmin=j;
                   5220:            ijmin=i;
                   5221:          }
                   5222:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5223:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5224:          if(j<0){
                   5225:            nberr++;
                   5226:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5227:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5228:          }
                   5229:          sum=sum+j;
                   5230:        }
                   5231:        jk= j/stepm;
                   5232:        jl= j -jk*stepm;
                   5233:        ju= j -(jk+1)*stepm;
                   5234:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5235:          if(jl==0){
                   5236:            dh[mi][i]=jk;
                   5237:            bh[mi][i]=0;
                   5238:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5239:                  * to avoid the price of an extra matrix product in likelihood */
                   5240:            dh[mi][i]=jk+1;
                   5241:            bh[mi][i]=ju;
                   5242:          }
                   5243:        }else{
                   5244:          if(jl <= -ju){
                   5245:            dh[mi][i]=jk;
                   5246:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5247:                                 * is higher than the multiple of stepm and negative otherwise.
                   5248:                                 */
                   5249:          }
                   5250:          else{
                   5251:            dh[mi][i]=jk+1;
                   5252:            bh[mi][i]=ju;
                   5253:          }
                   5254:          if(dh[mi][i]==0){
                   5255:            dh[mi][i]=1; /* At least one step */
                   5256:            bh[mi][i]=ju; /* At least one step */
                   5257:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5258:          }
                   5259:        } /* end if mle */
1.126     brouard  5260:       }
                   5261:     } /* end wave */
                   5262:   }
                   5263:   jmean=sum/k;
                   5264:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5265:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5266: }
1.126     brouard  5267: 
                   5268: /*********** Tricode ****************************/
1.220     brouard  5269:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5270:  {
                   5271:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5272:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5273:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5274:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5275:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5276:     */
1.130     brouard  5277: 
1.242     brouard  5278:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5279:    int modmaxcovj=0; /* Modality max of covariates j */
                   5280:    int cptcode=0; /* Modality max of covariates j */
                   5281:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5282: 
                   5283: 
1.242     brouard  5284:    /* cptcoveff=0;  */
                   5285:    /* *cptcov=0; */
1.126     brouard  5286:  
1.242     brouard  5287:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5288: 
1.242     brouard  5289:    /* Loop on covariates without age and products and no quantitative variable */
                   5290:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5291:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5292:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5293:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5294:        switch(Fixed[k]) {
                   5295:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5296:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5297:           ij=(int)(covar[Tvar[k]][i]);
                   5298:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5299:            * If product of Vn*Vm, still boolean *:
                   5300:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5301:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5302:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5303:              modality of the nth covariate of individual i. */
                   5304:           if (ij > modmaxcovj)
                   5305:             modmaxcovj=ij; 
                   5306:           else if (ij < modmincovj) 
                   5307:             modmincovj=ij; 
                   5308:           if ((ij < -1) && (ij > NCOVMAX)){
                   5309:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5310:             exit(1);
                   5311:           }else
                   5312:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5313:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5314:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5315:           /* getting the maximum value of the modality of the covariate
                   5316:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5317:              female ies 1, then modmaxcovj=1.
                   5318:           */
                   5319:         } /* end for loop on individuals i */
                   5320:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5321:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5322:         cptcode=modmaxcovj;
                   5323:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5324:         /*for (i=0; i<=cptcode; i++) {*/
                   5325:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5326:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5327:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5328:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5329:             if( j != -1){
                   5330:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5331:                                  covariate for which somebody answered excluding 
                   5332:                                  undefined. Usually 2: 0 and 1. */
                   5333:             }
                   5334:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5335:                                     covariate for which somebody answered including 
                   5336:                                     undefined. Usually 3: -1, 0 and 1. */
                   5337:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5338:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5339:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5340:                        
1.242     brouard  5341:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5342:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5343:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5344:         /* modmincovj=3; modmaxcovj = 7; */
                   5345:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5346:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5347:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5348:         /* nbcode[Tvar[j]][ij]=k; */
                   5349:         /* nbcode[Tvar[j]][1]=0; */
                   5350:         /* nbcode[Tvar[j]][2]=1; */
                   5351:         /* nbcode[Tvar[j]][3]=2; */
                   5352:         /* To be continued (not working yet). */
                   5353:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5354:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5355:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5356:             break;
                   5357:           }
                   5358:           ij++;
                   5359:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5360:           cptcode = ij; /* New max modality for covar j */
                   5361:         } /* end of loop on modality i=-1 to 1 or more */
                   5362:         break;
                   5363:        case 1: /* Testing on varying covariate, could be simple and
                   5364:                * should look at waves or product of fixed *
                   5365:                * varying. No time to test -1, assuming 0 and 1 only */
                   5366:         ij=0;
                   5367:         for(i=0; i<=1;i++){
                   5368:           nbcode[Tvar[k]][++ij]=i;
                   5369:         }
                   5370:         break;
                   5371:        default:
                   5372:         break;
                   5373:        } /* end switch */
                   5374:      } /* end dummy test */
                   5375:     
                   5376:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5377:      /*        /\*recode from 0 *\/ */
                   5378:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5379:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5380:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5381:      /*        } */
                   5382:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5383:      /*        if (ij > ncodemax[j]) { */
                   5384:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5385:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5386:      /*          break; */
                   5387:      /*        } */
                   5388:      /*   }  /\* end of loop on modality k *\/ */
                   5389:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5390:   
                   5391:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5392:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5393:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5394:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5395:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5396:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5397:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5398:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5399:   
                   5400:    ij=0;
                   5401:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5402:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5403:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5404:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5405:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5406:        /* If product not in single variable we don't print results */
                   5407:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5408:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5409:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5410:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5411:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5412:        if(Fixed[k]!=0)
                   5413:         anyvaryingduminmodel=1;
                   5414:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5415:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5416:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5417:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5418:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5419:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5420:      } 
                   5421:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5422:    /* ij--; */
                   5423:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5424:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5425:                * because they can be excluded from the model and real
                   5426:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5427:    for(j=ij+1; j<= cptcovt; j++){
                   5428:      Tvaraff[j]=0;
                   5429:      Tmodelind[j]=0;
                   5430:    }
                   5431:    for(j=ntveff+1; j<= cptcovt; j++){
                   5432:      TmodelInvind[j]=0;
                   5433:    }
                   5434:    /* To be sorted */
                   5435:    ;
                   5436:  }
1.126     brouard  5437: 
1.145     brouard  5438: 
1.126     brouard  5439: /*********** Health Expectancies ****************/
                   5440: 
1.235     brouard  5441:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5442: 
                   5443: {
                   5444:   /* Health expectancies, no variances */
1.164     brouard  5445:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5446:   int nhstepma, nstepma; /* Decreasing with age */
                   5447:   double age, agelim, hf;
                   5448:   double ***p3mat;
                   5449:   double eip;
                   5450: 
1.238     brouard  5451:   /* pstamp(ficreseij); */
1.126     brouard  5452:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5453:   fprintf(ficreseij,"# Age");
                   5454:   for(i=1; i<=nlstate;i++){
                   5455:     for(j=1; j<=nlstate;j++){
                   5456:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5457:     }
                   5458:     fprintf(ficreseij," e%1d. ",i);
                   5459:   }
                   5460:   fprintf(ficreseij,"\n");
                   5461: 
                   5462:   
                   5463:   if(estepm < stepm){
                   5464:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5465:   }
                   5466:   else  hstepm=estepm;   
                   5467:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5468:    * This is mainly to measure the difference between two models: for example
                   5469:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5470:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5471:    * progression in between and thus overestimating or underestimating according
                   5472:    * to the curvature of the survival function. If, for the same date, we 
                   5473:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5474:    * to compare the new estimate of Life expectancy with the same linear 
                   5475:    * hypothesis. A more precise result, taking into account a more precise
                   5476:    * curvature will be obtained if estepm is as small as stepm. */
                   5477: 
                   5478:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5479:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5480:      nhstepm is the number of hstepm from age to agelim 
                   5481:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5482:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5483:      and note for a fixed period like estepm months */
                   5484:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5485:      survival function given by stepm (the optimization length). Unfortunately it
                   5486:      means that if the survival funtion is printed only each two years of age and if
                   5487:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5488:      results. So we changed our mind and took the option of the best precision.
                   5489:   */
                   5490:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5491: 
                   5492:   agelim=AGESUP;
                   5493:   /* If stepm=6 months */
                   5494:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5495:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5496:     
                   5497: /* nhstepm age range expressed in number of stepm */
                   5498:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5499:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5500:   /* if (stepm >= YEARM) hstepm=1;*/
                   5501:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5502:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5503: 
                   5504:   for (age=bage; age<=fage; age ++){ 
                   5505:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5506:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5507:     /* if (stepm >= YEARM) hstepm=1;*/
                   5508:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5509: 
                   5510:     /* If stepm=6 months */
                   5511:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5512:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5513:     
1.235     brouard  5514:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5515:     
                   5516:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5517:     
                   5518:     printf("%d|",(int)age);fflush(stdout);
                   5519:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5520:     
                   5521:     /* Computing expectancies */
                   5522:     for(i=1; i<=nlstate;i++)
                   5523:       for(j=1; j<=nlstate;j++)
                   5524:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5525:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5526:          
                   5527:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5528: 
                   5529:        }
                   5530: 
                   5531:     fprintf(ficreseij,"%3.0f",age );
                   5532:     for(i=1; i<=nlstate;i++){
                   5533:       eip=0;
                   5534:       for(j=1; j<=nlstate;j++){
                   5535:        eip +=eij[i][j][(int)age];
                   5536:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5537:       }
                   5538:       fprintf(ficreseij,"%9.4f", eip );
                   5539:     }
                   5540:     fprintf(ficreseij,"\n");
                   5541:     
                   5542:   }
                   5543:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5544:   printf("\n");
                   5545:   fprintf(ficlog,"\n");
                   5546:   
                   5547: }
                   5548: 
1.235     brouard  5549:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5550: 
                   5551: {
                   5552:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5553:      to initial status i, ei. .
1.126     brouard  5554:   */
                   5555:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5556:   int nhstepma, nstepma; /* Decreasing with age */
                   5557:   double age, agelim, hf;
                   5558:   double ***p3matp, ***p3matm, ***varhe;
                   5559:   double **dnewm,**doldm;
                   5560:   double *xp, *xm;
                   5561:   double **gp, **gm;
                   5562:   double ***gradg, ***trgradg;
                   5563:   int theta;
                   5564: 
                   5565:   double eip, vip;
                   5566: 
                   5567:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5568:   xp=vector(1,npar);
                   5569:   xm=vector(1,npar);
                   5570:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5571:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5572:   
                   5573:   pstamp(ficresstdeij);
                   5574:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5575:   fprintf(ficresstdeij,"# Age");
                   5576:   for(i=1; i<=nlstate;i++){
                   5577:     for(j=1; j<=nlstate;j++)
                   5578:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5579:     fprintf(ficresstdeij," e%1d. ",i);
                   5580:   }
                   5581:   fprintf(ficresstdeij,"\n");
                   5582: 
                   5583:   pstamp(ficrescveij);
                   5584:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5585:   fprintf(ficrescveij,"# Age");
                   5586:   for(i=1; i<=nlstate;i++)
                   5587:     for(j=1; j<=nlstate;j++){
                   5588:       cptj= (j-1)*nlstate+i;
                   5589:       for(i2=1; i2<=nlstate;i2++)
                   5590:        for(j2=1; j2<=nlstate;j2++){
                   5591:          cptj2= (j2-1)*nlstate+i2;
                   5592:          if(cptj2 <= cptj)
                   5593:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5594:        }
                   5595:     }
                   5596:   fprintf(ficrescveij,"\n");
                   5597:   
                   5598:   if(estepm < stepm){
                   5599:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5600:   }
                   5601:   else  hstepm=estepm;   
                   5602:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5603:    * This is mainly to measure the difference between two models: for example
                   5604:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5605:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5606:    * progression in between and thus overestimating or underestimating according
                   5607:    * to the curvature of the survival function. If, for the same date, we 
                   5608:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5609:    * to compare the new estimate of Life expectancy with the same linear 
                   5610:    * hypothesis. A more precise result, taking into account a more precise
                   5611:    * curvature will be obtained if estepm is as small as stepm. */
                   5612: 
                   5613:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5614:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5615:      nhstepm is the number of hstepm from age to agelim 
                   5616:      nstepm is the number of stepm from age to agelin. 
                   5617:      Look at hpijx to understand the reason of that which relies in memory size
                   5618:      and note for a fixed period like estepm months */
                   5619:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5620:      survival function given by stepm (the optimization length). Unfortunately it
                   5621:      means that if the survival funtion is printed only each two years of age and if
                   5622:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5623:      results. So we changed our mind and took the option of the best precision.
                   5624:   */
                   5625:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5626: 
                   5627:   /* If stepm=6 months */
                   5628:   /* nhstepm age range expressed in number of stepm */
                   5629:   agelim=AGESUP;
                   5630:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5631:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5632:   /* if (stepm >= YEARM) hstepm=1;*/
                   5633:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5634:   
                   5635:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5636:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5637:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5638:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5639:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5640:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5641: 
                   5642:   for (age=bage; age<=fage; age ++){ 
                   5643:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5644:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5645:     /* if (stepm >= YEARM) hstepm=1;*/
                   5646:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5647:                
1.126     brouard  5648:     /* If stepm=6 months */
                   5649:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5650:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5651:     
                   5652:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5653:                
1.126     brouard  5654:     /* Computing  Variances of health expectancies */
                   5655:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5656:        decrease memory allocation */
                   5657:     for(theta=1; theta <=npar; theta++){
                   5658:       for(i=1; i<=npar; i++){ 
1.222     brouard  5659:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5660:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5661:       }
1.235     brouard  5662:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5663:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5664:                        
1.126     brouard  5665:       for(j=1; j<= nlstate; j++){
1.222     brouard  5666:        for(i=1; i<=nlstate; i++){
                   5667:          for(h=0; h<=nhstepm-1; h++){
                   5668:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5669:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5670:          }
                   5671:        }
1.126     brouard  5672:       }
1.218     brouard  5673:                        
1.126     brouard  5674:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5675:        for(h=0; h<=nhstepm-1; h++){
                   5676:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5677:        }
1.126     brouard  5678:     }/* End theta */
                   5679:     
                   5680:     
                   5681:     for(h=0; h<=nhstepm-1; h++)
                   5682:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5683:        for(theta=1; theta <=npar; theta++)
                   5684:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5685:     
1.218     brouard  5686:                
1.222     brouard  5687:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5688:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5689:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5690:                
1.222     brouard  5691:     printf("%d|",(int)age);fflush(stdout);
                   5692:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5693:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5694:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5695:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5696:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5697:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5698:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5699:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5700:       }
                   5701:     }
1.218     brouard  5702:                
1.126     brouard  5703:     /* Computing expectancies */
1.235     brouard  5704:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5705:     for(i=1; i<=nlstate;i++)
                   5706:       for(j=1; j<=nlstate;j++)
1.222     brouard  5707:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5708:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5709:                                        
1.222     brouard  5710:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5711:                                        
1.222     brouard  5712:        }
1.269     brouard  5713: 
                   5714:     /* Standard deviation of expectancies ij */                
1.126     brouard  5715:     fprintf(ficresstdeij,"%3.0f",age );
                   5716:     for(i=1; i<=nlstate;i++){
                   5717:       eip=0.;
                   5718:       vip=0.;
                   5719:       for(j=1; j<=nlstate;j++){
1.222     brouard  5720:        eip += eij[i][j][(int)age];
                   5721:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5722:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5723:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5724:       }
                   5725:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5726:     }
                   5727:     fprintf(ficresstdeij,"\n");
1.218     brouard  5728:                
1.269     brouard  5729:     /* Variance of expectancies ij */          
1.126     brouard  5730:     fprintf(ficrescveij,"%3.0f",age );
                   5731:     for(i=1; i<=nlstate;i++)
                   5732:       for(j=1; j<=nlstate;j++){
1.222     brouard  5733:        cptj= (j-1)*nlstate+i;
                   5734:        for(i2=1; i2<=nlstate;i2++)
                   5735:          for(j2=1; j2<=nlstate;j2++){
                   5736:            cptj2= (j2-1)*nlstate+i2;
                   5737:            if(cptj2 <= cptj)
                   5738:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5739:          }
1.126     brouard  5740:       }
                   5741:     fprintf(ficrescveij,"\n");
1.218     brouard  5742:                
1.126     brouard  5743:   }
                   5744:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5745:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5746:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5747:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5748:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5749:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5750:   printf("\n");
                   5751:   fprintf(ficlog,"\n");
1.218     brouard  5752:        
1.126     brouard  5753:   free_vector(xm,1,npar);
                   5754:   free_vector(xp,1,npar);
                   5755:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5756:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5757:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5758: }
1.218     brouard  5759:  
1.126     brouard  5760: /************ Variance ******************/
1.235     brouard  5761:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5762:  {
                   5763:    /* Variance of health expectancies */
                   5764:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5765:    /* double **newm;*/
                   5766:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5767:   
                   5768:    /* int movingaverage(); */
                   5769:    double **dnewm,**doldm;
                   5770:    double **dnewmp,**doldmp;
                   5771:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5772:    int k;
                   5773:    double *xp;
                   5774:    double **gp, **gm;  /* for var eij */
                   5775:    double ***gradg, ***trgradg; /*for var eij */
                   5776:    double **gradgp, **trgradgp; /* for var p point j */
                   5777:    double *gpp, *gmp; /* for var p point j */
                   5778:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5779:    double ***p3mat;
                   5780:    double age,agelim, hf;
                   5781:    /* double ***mobaverage; */
                   5782:    int theta;
                   5783:    char digit[4];
                   5784:    char digitp[25];
                   5785: 
                   5786:    char fileresprobmorprev[FILENAMELENGTH];
                   5787: 
                   5788:    if(popbased==1){
                   5789:      if(mobilav!=0)
                   5790:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5791:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5792:    }
                   5793:    else 
                   5794:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5795: 
1.218     brouard  5796:    /* if (mobilav!=0) { */
                   5797:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5798:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5799:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5800:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5801:    /*   } */
                   5802:    /* } */
                   5803: 
                   5804:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5805:    sprintf(digit,"%-d",ij);
                   5806:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5807:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5808:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5809:    strcat(fileresprobmorprev,fileresu);
                   5810:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5811:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5812:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5813:    }
                   5814:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5815:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5816:    pstamp(ficresprobmorprev);
                   5817:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5818:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5819:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5820:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5821:    }
                   5822:    for(j=1;j<=cptcoveff;j++) 
                   5823:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5824:    fprintf(ficresprobmorprev,"\n");
                   5825: 
1.218     brouard  5826:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5827:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5828:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5829:      for(i=1; i<=nlstate;i++)
                   5830:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5831:    }  
                   5832:    fprintf(ficresprobmorprev,"\n");
                   5833:   
                   5834:    fprintf(ficgp,"\n# Routine varevsij");
                   5835:    fprintf(ficgp,"\nunset title \n");
                   5836:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5837:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5838:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5839:    /*   } */
                   5840:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5841:    pstamp(ficresvij);
                   5842:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5843:    if(popbased==1)
                   5844:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5845:    else
                   5846:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5847:    fprintf(ficresvij,"# Age");
                   5848:    for(i=1; i<=nlstate;i++)
                   5849:      for(j=1; j<=nlstate;j++)
                   5850:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5851:    fprintf(ficresvij,"\n");
                   5852: 
                   5853:    xp=vector(1,npar);
                   5854:    dnewm=matrix(1,nlstate,1,npar);
                   5855:    doldm=matrix(1,nlstate,1,nlstate);
                   5856:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5857:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5858: 
                   5859:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5860:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5861:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5862:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5863:   
1.218     brouard  5864:    if(estepm < stepm){
                   5865:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5866:    }
                   5867:    else  hstepm=estepm;   
                   5868:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5869:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5870:       nhstepm is the number of hstepm from age to agelim 
                   5871:       nstepm is the number of stepm from age to agelim. 
                   5872:       Look at function hpijx to understand why because of memory size limitations, 
                   5873:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5874:       survival function given by stepm (the optimization length). Unfortunately it
                   5875:       means that if the survival funtion is printed every two years of age and if
                   5876:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5877:       results. So we changed our mind and took the option of the best precision.
                   5878:    */
                   5879:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5880:    agelim = AGESUP;
                   5881:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5882:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5883:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5884:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5885:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5886:      gp=matrix(0,nhstepm,1,nlstate);
                   5887:      gm=matrix(0,nhstepm,1,nlstate);
                   5888:                
                   5889:                
                   5890:      for(theta=1; theta <=npar; theta++){
                   5891:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5892:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5893:        }
                   5894:                        
1.242     brouard  5895:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5896:                        
                   5897:        if (popbased==1) {
                   5898:         if(mobilav ==0){
                   5899:           for(i=1; i<=nlstate;i++)
                   5900:             prlim[i][i]=probs[(int)age][i][ij];
                   5901:         }else{ /* mobilav */ 
                   5902:           for(i=1; i<=nlstate;i++)
                   5903:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5904:         }
                   5905:        }
                   5906:                        
1.235     brouard  5907:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5908:        for(j=1; j<= nlstate; j++){
                   5909:         for(h=0; h<=nhstepm; h++){
                   5910:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5911:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5912:         }
                   5913:        }
                   5914:        /* Next for computing probability of death (h=1 means
                   5915:          computed over hstepm matrices product = hstepm*stepm months) 
                   5916:          as a weighted average of prlim.
                   5917:        */
                   5918:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5919:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5920:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5921:        }    
                   5922:        /* end probability of death */
                   5923:                        
                   5924:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5925:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5926:                        
1.242     brouard  5927:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5928:                        
                   5929:        if (popbased==1) {
                   5930:         if(mobilav ==0){
                   5931:           for(i=1; i<=nlstate;i++)
                   5932:             prlim[i][i]=probs[(int)age][i][ij];
                   5933:         }else{ /* mobilav */ 
                   5934:           for(i=1; i<=nlstate;i++)
                   5935:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5936:         }
                   5937:        }
                   5938:                        
1.235     brouard  5939:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5940:                        
                   5941:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5942:         for(h=0; h<=nhstepm; h++){
                   5943:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5944:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5945:         }
                   5946:        }
                   5947:        /* This for computing probability of death (h=1 means
                   5948:          computed over hstepm matrices product = hstepm*stepm months) 
                   5949:          as a weighted average of prlim.
                   5950:        */
                   5951:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5952:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5953:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5954:        }    
                   5955:        /* end probability of death */
                   5956:                        
                   5957:        for(j=1; j<= nlstate; j++) /* vareij */
                   5958:         for(h=0; h<=nhstepm; h++){
                   5959:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5960:         }
                   5961:                        
                   5962:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5963:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5964:        }
                   5965:                        
                   5966:      } /* End theta */
                   5967:                
                   5968:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5969:                
                   5970:      for(h=0; h<=nhstepm; h++) /* veij */
                   5971:        for(j=1; j<=nlstate;j++)
                   5972:         for(theta=1; theta <=npar; theta++)
                   5973:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5974:                
                   5975:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5976:        for(theta=1; theta <=npar; theta++)
                   5977:         trgradgp[j][theta]=gradgp[theta][j];
                   5978:                
                   5979:                
                   5980:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5981:      for(i=1;i<=nlstate;i++)
                   5982:        for(j=1;j<=nlstate;j++)
                   5983:         vareij[i][j][(int)age] =0.;
                   5984:                
                   5985:      for(h=0;h<=nhstepm;h++){
                   5986:        for(k=0;k<=nhstepm;k++){
                   5987:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5988:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5989:         for(i=1;i<=nlstate;i++)
                   5990:           for(j=1;j<=nlstate;j++)
                   5991:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5992:        }
                   5993:      }
                   5994:                
                   5995:      /* pptj */
                   5996:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5997:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5998:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5999:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6000:         varppt[j][i]=doldmp[j][i];
                   6001:      /* end ppptj */
                   6002:      /*  x centered again */
                   6003:                
1.242     brouard  6004:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6005:                
                   6006:      if (popbased==1) {
                   6007:        if(mobilav ==0){
                   6008:         for(i=1; i<=nlstate;i++)
                   6009:           prlim[i][i]=probs[(int)age][i][ij];
                   6010:        }else{ /* mobilav */ 
                   6011:         for(i=1; i<=nlstate;i++)
                   6012:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6013:        }
                   6014:      }
                   6015:                
                   6016:      /* This for computing probability of death (h=1 means
                   6017:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6018:        as a weighted average of prlim.
                   6019:      */
1.235     brouard  6020:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6021:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6022:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6023:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6024:      }    
                   6025:      /* end probability of death */
                   6026:                
                   6027:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6028:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6029:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6030:        for(i=1; i<=nlstate;i++){
                   6031:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6032:        }
                   6033:      } 
                   6034:      fprintf(ficresprobmorprev,"\n");
                   6035:                
                   6036:      fprintf(ficresvij,"%.0f ",age );
                   6037:      for(i=1; i<=nlstate;i++)
                   6038:        for(j=1; j<=nlstate;j++){
                   6039:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6040:        }
                   6041:      fprintf(ficresvij,"\n");
                   6042:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6043:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6044:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6045:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6046:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6047:    } /* End age */
                   6048:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6049:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6050:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6051:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6052:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6053:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6054:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6055:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6056:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6057:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6058:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6059:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6060:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6061:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6062:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6063:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6064:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6065:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6066:     */
1.218     brouard  6067:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6068:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6069: 
1.218     brouard  6070:    free_vector(xp,1,npar);
                   6071:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6072:    free_matrix(dnewm,1,nlstate,1,npar);
                   6073:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6074:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6075:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6076:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6077:    fclose(ficresprobmorprev);
                   6078:    fflush(ficgp);
                   6079:    fflush(fichtm); 
                   6080:  }  /* end varevsij */
1.126     brouard  6081: 
                   6082: /************ Variance of prevlim ******************/
1.269     brouard  6083:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6084: {
1.205     brouard  6085:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6086:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6087: 
1.268     brouard  6088:   double **dnewmpar,**doldm;
1.126     brouard  6089:   int i, j, nhstepm, hstepm;
                   6090:   double *xp;
                   6091:   double *gp, *gm;
                   6092:   double **gradg, **trgradg;
1.208     brouard  6093:   double **mgm, **mgp;
1.126     brouard  6094:   double age,agelim;
                   6095:   int theta;
                   6096:   
                   6097:   pstamp(ficresvpl);
                   6098:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6099:   fprintf(ficresvpl,"# Age ");
                   6100:   if(nresult >=1)
                   6101:     fprintf(ficresvpl," Result# ");
1.126     brouard  6102:   for(i=1; i<=nlstate;i++)
                   6103:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6104:   fprintf(ficresvpl,"\n");
                   6105: 
                   6106:   xp=vector(1,npar);
1.268     brouard  6107:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6108:   doldm=matrix(1,nlstate,1,nlstate);
                   6109:   
                   6110:   hstepm=1*YEARM; /* Every year of age */
                   6111:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6112:   agelim = AGESUP;
                   6113:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6114:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6115:     if (stepm >= YEARM) hstepm=1;
                   6116:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6117:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6118:     mgp=matrix(1,npar,1,nlstate);
                   6119:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6120:     gp=vector(1,nlstate);
                   6121:     gm=vector(1,nlstate);
                   6122: 
                   6123:     for(theta=1; theta <=npar; theta++){
                   6124:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6125:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6126:       }
1.209     brouard  6127:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6128:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6129:       else
1.235     brouard  6130:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6131:       for(i=1;i<=nlstate;i++){
1.126     brouard  6132:        gp[i] = prlim[i][i];
1.208     brouard  6133:        mgp[theta][i] = prlim[i][i];
                   6134:       }
1.126     brouard  6135:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6136:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6137:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6138:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6139:       else
1.235     brouard  6140:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6141:       for(i=1;i<=nlstate;i++){
1.126     brouard  6142:        gm[i] = prlim[i][i];
1.208     brouard  6143:        mgm[theta][i] = prlim[i][i];
                   6144:       }
1.126     brouard  6145:       for(i=1;i<=nlstate;i++)
                   6146:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6147:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6148:     } /* End theta */
                   6149: 
                   6150:     trgradg =matrix(1,nlstate,1,npar);
                   6151: 
                   6152:     for(j=1; j<=nlstate;j++)
                   6153:       for(theta=1; theta <=npar; theta++)
                   6154:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6155:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6156:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6157:     /*   for(j=1; j<=nlstate;j++){ */
                   6158:     /*         printf(" %d ",j); */
                   6159:     /*         for(theta=1; theta <=npar; theta++) */
                   6160:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6161:     /*         printf("\n "); */
                   6162:     /*   } */
                   6163:     /* } */
                   6164:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6165:     /*   printf("\n gradg %d ",(int)age); */
                   6166:     /*   for(j=1; j<=nlstate;j++){ */
                   6167:     /*         printf("%d ",j); */
                   6168:     /*         for(theta=1; theta <=npar; theta++) */
                   6169:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6170:     /*         printf("\n "); */
                   6171:     /*   } */
                   6172:     /* } */
1.126     brouard  6173: 
                   6174:     for(i=1;i<=nlstate;i++)
                   6175:       varpl[i][(int)age] =0.;
1.209     brouard  6176:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6177:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6178:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6179:     }else{
1.268     brouard  6180:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6181:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6182:     }
1.126     brouard  6183:     for(i=1;i<=nlstate;i++)
                   6184:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6185: 
                   6186:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6187:     if(nresult >=1)
                   6188:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6189:     for(i=1; i<=nlstate;i++)
                   6190:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6191:     fprintf(ficresvpl,"\n");
                   6192:     free_vector(gp,1,nlstate);
                   6193:     free_vector(gm,1,nlstate);
1.208     brouard  6194:     free_matrix(mgm,1,npar,1,nlstate);
                   6195:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6196:     free_matrix(gradg,1,npar,1,nlstate);
                   6197:     free_matrix(trgradg,1,nlstate,1,npar);
                   6198:   } /* End age */
                   6199: 
                   6200:   free_vector(xp,1,npar);
                   6201:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6202:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6203: 
                   6204: }
                   6205: 
                   6206: 
                   6207: /************ Variance of backprevalence limit ******************/
1.269     brouard  6208:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6209: {
                   6210:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6211:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6212: 
                   6213:   double **dnewmpar,**doldm;
                   6214:   int i, j, nhstepm, hstepm;
                   6215:   double *xp;
                   6216:   double *gp, *gm;
                   6217:   double **gradg, **trgradg;
                   6218:   double **mgm, **mgp;
                   6219:   double age,agelim;
                   6220:   int theta;
                   6221:   
                   6222:   pstamp(ficresvbl);
                   6223:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6224:   fprintf(ficresvbl,"# Age ");
                   6225:   if(nresult >=1)
                   6226:     fprintf(ficresvbl," Result# ");
                   6227:   for(i=1; i<=nlstate;i++)
                   6228:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6229:   fprintf(ficresvbl,"\n");
                   6230: 
                   6231:   xp=vector(1,npar);
                   6232:   dnewmpar=matrix(1,nlstate,1,npar);
                   6233:   doldm=matrix(1,nlstate,1,nlstate);
                   6234:   
                   6235:   hstepm=1*YEARM; /* Every year of age */
                   6236:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6237:   agelim = AGEINF;
                   6238:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6239:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6240:     if (stepm >= YEARM) hstepm=1;
                   6241:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6242:     gradg=matrix(1,npar,1,nlstate);
                   6243:     mgp=matrix(1,npar,1,nlstate);
                   6244:     mgm=matrix(1,npar,1,nlstate);
                   6245:     gp=vector(1,nlstate);
                   6246:     gm=vector(1,nlstate);
                   6247: 
                   6248:     for(theta=1; theta <=npar; theta++){
                   6249:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6250:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6251:       }
                   6252:       if(mobilavproj > 0 )
                   6253:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6254:       else
                   6255:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6256:       for(i=1;i<=nlstate;i++){
                   6257:        gp[i] = bprlim[i][i];
                   6258:        mgp[theta][i] = bprlim[i][i];
                   6259:       }
                   6260:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6261:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6262:        if(mobilavproj > 0 )
                   6263:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6264:        else
                   6265:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6266:       for(i=1;i<=nlstate;i++){
                   6267:        gm[i] = bprlim[i][i];
                   6268:        mgm[theta][i] = bprlim[i][i];
                   6269:       }
                   6270:       for(i=1;i<=nlstate;i++)
                   6271:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6272:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6273:     } /* End theta */
                   6274: 
                   6275:     trgradg =matrix(1,nlstate,1,npar);
                   6276: 
                   6277:     for(j=1; j<=nlstate;j++)
                   6278:       for(theta=1; theta <=npar; theta++)
                   6279:        trgradg[j][theta]=gradg[theta][j];
                   6280:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6281:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6282:     /*   for(j=1; j<=nlstate;j++){ */
                   6283:     /*         printf(" %d ",j); */
                   6284:     /*         for(theta=1; theta <=npar; theta++) */
                   6285:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6286:     /*         printf("\n "); */
                   6287:     /*   } */
                   6288:     /* } */
                   6289:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6290:     /*   printf("\n gradg %d ",(int)age); */
                   6291:     /*   for(j=1; j<=nlstate;j++){ */
                   6292:     /*         printf("%d ",j); */
                   6293:     /*         for(theta=1; theta <=npar; theta++) */
                   6294:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6295:     /*         printf("\n "); */
                   6296:     /*   } */
                   6297:     /* } */
                   6298: 
                   6299:     for(i=1;i<=nlstate;i++)
                   6300:       varbpl[i][(int)age] =0.;
                   6301:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6302:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6303:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6304:     }else{
                   6305:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6306:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6307:     }
                   6308:     for(i=1;i<=nlstate;i++)
                   6309:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6310: 
                   6311:     fprintf(ficresvbl,"%.0f ",age );
                   6312:     if(nresult >=1)
                   6313:       fprintf(ficresvbl,"%d ",nres );
                   6314:     for(i=1; i<=nlstate;i++)
                   6315:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6316:     fprintf(ficresvbl,"\n");
                   6317:     free_vector(gp,1,nlstate);
                   6318:     free_vector(gm,1,nlstate);
                   6319:     free_matrix(mgm,1,npar,1,nlstate);
                   6320:     free_matrix(mgp,1,npar,1,nlstate);
                   6321:     free_matrix(gradg,1,npar,1,nlstate);
                   6322:     free_matrix(trgradg,1,nlstate,1,npar);
                   6323:   } /* End age */
                   6324: 
                   6325:   free_vector(xp,1,npar);
                   6326:   free_matrix(doldm,1,nlstate,1,npar);
                   6327:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6328: 
                   6329: }
                   6330: 
                   6331: /************ Variance of one-step probabilities  ******************/
                   6332: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6333:  {
                   6334:    int i, j=0,  k1, l1, tj;
                   6335:    int k2, l2, j1,  z1;
                   6336:    int k=0, l;
                   6337:    int first=1, first1, first2;
                   6338:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6339:    double **dnewm,**doldm;
                   6340:    double *xp;
                   6341:    double *gp, *gm;
                   6342:    double **gradg, **trgradg;
                   6343:    double **mu;
                   6344:    double age, cov[NCOVMAX+1];
                   6345:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6346:    int theta;
                   6347:    char fileresprob[FILENAMELENGTH];
                   6348:    char fileresprobcov[FILENAMELENGTH];
                   6349:    char fileresprobcor[FILENAMELENGTH];
                   6350:    double ***varpij;
                   6351: 
                   6352:    strcpy(fileresprob,"PROB_"); 
                   6353:    strcat(fileresprob,fileres);
                   6354:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6355:      printf("Problem with resultfile: %s\n", fileresprob);
                   6356:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6357:    }
                   6358:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6359:    strcat(fileresprobcov,fileresu);
                   6360:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6361:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6362:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6363:    }
                   6364:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6365:    strcat(fileresprobcor,fileresu);
                   6366:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6367:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6368:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6369:    }
                   6370:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6371:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6372:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6373:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6374:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6375:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6376:    pstamp(ficresprob);
                   6377:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6378:    fprintf(ficresprob,"# Age");
                   6379:    pstamp(ficresprobcov);
                   6380:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6381:    fprintf(ficresprobcov,"# Age");
                   6382:    pstamp(ficresprobcor);
                   6383:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6384:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6385: 
                   6386: 
1.222     brouard  6387:    for(i=1; i<=nlstate;i++)
                   6388:      for(j=1; j<=(nlstate+ndeath);j++){
                   6389:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6390:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6391:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6392:      }  
                   6393:    /* fprintf(ficresprob,"\n");
                   6394:       fprintf(ficresprobcov,"\n");
                   6395:       fprintf(ficresprobcor,"\n");
                   6396:    */
                   6397:    xp=vector(1,npar);
                   6398:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6399:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6400:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6401:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6402:    first=1;
                   6403:    fprintf(ficgp,"\n# Routine varprob");
                   6404:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6405:    fprintf(fichtm,"\n");
                   6406: 
1.266     brouard  6407:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6408:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6409:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6410: and drawn. It helps understanding how is the covariance between two incidences.\
                   6411:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6412:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6413: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6414: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6415: standard deviations wide on each axis. <br>\
                   6416:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6417:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6418: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6419: 
1.222     brouard  6420:    cov[1]=1;
                   6421:    /* tj=cptcoveff; */
1.225     brouard  6422:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6423:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6424:    j1=0;
1.224     brouard  6425:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6426:      if  (cptcovn>0) {
                   6427:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6428:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6429:        fprintf(ficresprob, "**********\n#\n");
                   6430:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6431:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6432:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6433:                        
1.222     brouard  6434:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6435:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6436:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6437:                        
                   6438:                        
1.222     brouard  6439:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6440:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6441:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6442:                        
1.222     brouard  6443:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6444:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6445:        fprintf(ficresprobcor, "**********\n#");    
                   6446:        if(invalidvarcomb[j1]){
                   6447:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6448:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6449:         continue;
                   6450:        }
                   6451:      }
                   6452:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6453:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6454:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6455:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6456:      for (age=bage; age<=fage; age ++){ 
                   6457:        cov[2]=age;
                   6458:        if(nagesqr==1)
                   6459:         cov[3]= age*age;
                   6460:        for (k=1; k<=cptcovn;k++) {
                   6461:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6462:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6463:                                                                    * 1  1 1 1 1
                   6464:                                                                    * 2  2 1 1 1
                   6465:                                                                    * 3  1 2 1 1
                   6466:                                                                    */
                   6467:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6468:        }
                   6469:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6470:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6471:        for (k=1; k<=cptcovprod;k++)
                   6472:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6473:                        
                   6474:                        
1.222     brouard  6475:        for(theta=1; theta <=npar; theta++){
                   6476:         for(i=1; i<=npar; i++)
                   6477:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6478:                                
1.222     brouard  6479:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6480:                                
1.222     brouard  6481:         k=0;
                   6482:         for(i=1; i<= (nlstate); i++){
                   6483:           for(j=1; j<=(nlstate+ndeath);j++){
                   6484:             k=k+1;
                   6485:             gp[k]=pmmij[i][j];
                   6486:           }
                   6487:         }
1.220     brouard  6488:                                
1.222     brouard  6489:         for(i=1; i<=npar; i++)
                   6490:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6491:                                
1.222     brouard  6492:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6493:         k=0;
                   6494:         for(i=1; i<=(nlstate); i++){
                   6495:           for(j=1; j<=(nlstate+ndeath);j++){
                   6496:             k=k+1;
                   6497:             gm[k]=pmmij[i][j];
                   6498:           }
                   6499:         }
1.220     brouard  6500:                                
1.222     brouard  6501:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6502:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6503:        }
1.126     brouard  6504: 
1.222     brouard  6505:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6506:         for(theta=1; theta <=npar; theta++)
                   6507:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6508:                        
1.222     brouard  6509:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6510:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6511:                        
1.222     brouard  6512:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6513:                        
1.222     brouard  6514:        k=0;
                   6515:        for(i=1; i<=(nlstate); i++){
                   6516:         for(j=1; j<=(nlstate+ndeath);j++){
                   6517:           k=k+1;
                   6518:           mu[k][(int) age]=pmmij[i][j];
                   6519:         }
                   6520:        }
                   6521:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6522:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6523:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6524:                        
1.222     brouard  6525:        /*printf("\n%d ",(int)age);
                   6526:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6527:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6528:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6529:         }*/
1.220     brouard  6530:                        
1.222     brouard  6531:        fprintf(ficresprob,"\n%d ",(int)age);
                   6532:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6533:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6534:                        
1.222     brouard  6535:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6536:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6537:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6538:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6539:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6540:        }
                   6541:        i=0;
                   6542:        for (k=1; k<=(nlstate);k++){
                   6543:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6544:           i++;
                   6545:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6546:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6547:           for (j=1; j<=i;j++){
                   6548:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6549:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6550:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6551:           }
                   6552:         }
                   6553:        }/* end of loop for state */
                   6554:      } /* end of loop for age */
                   6555:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6556:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6557:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6558:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6559:     
                   6560:      /* Confidence intervalle of pij  */
                   6561:      /*
                   6562:        fprintf(ficgp,"\nunset parametric;unset label");
                   6563:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6564:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6565:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6566:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6567:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6568:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6569:      */
                   6570:                
                   6571:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6572:      first1=1;first2=2;
                   6573:      for (k2=1; k2<=(nlstate);k2++){
                   6574:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6575:         if(l2==k2) continue;
                   6576:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6577:         for (k1=1; k1<=(nlstate);k1++){
                   6578:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6579:             if(l1==k1) continue;
                   6580:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6581:             if(i<=j) continue;
                   6582:             for (age=bage; age<=fage; age ++){ 
                   6583:               if ((int)age %5==0){
                   6584:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6585:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6586:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6587:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6588:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6589:                 c12=cv12/sqrt(v1*v2);
                   6590:                 /* Computing eigen value of matrix of covariance */
                   6591:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6592:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6593:                 if ((lc2 <0) || (lc1 <0) ){
                   6594:                   if(first2==1){
                   6595:                     first1=0;
                   6596:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6597:                   }
                   6598:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6599:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6600:                   /* lc2=fabs(lc2); */
                   6601:                 }
1.220     brouard  6602:                                                                
1.222     brouard  6603:                 /* Eigen vectors */
                   6604:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6605:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6606:                 v21=(lc1-v1)/cv12*v11;
                   6607:                 v12=-v21;
                   6608:                 v22=v11;
                   6609:                 tnalp=v21/v11;
                   6610:                 if(first1==1){
                   6611:                   first1=0;
                   6612:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6613:                 }
                   6614:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6615:                 /*printf(fignu*/
                   6616:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6617:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6618:                 if(first==1){
                   6619:                   first=0;
                   6620:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6621:                   fprintf(ficgp,"\nset parametric;unset label");
                   6622:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6623:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6624:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6625:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6626: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6627:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6628:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6629:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6630:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6631:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6632:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6633:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6634:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6635:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6636:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6637:                 }else{
                   6638:                   first=0;
                   6639:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6640:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6641:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6642:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6643:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6644:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6645:                 }/* if first */
                   6646:               } /* age mod 5 */
                   6647:             } /* end loop age */
                   6648:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6649:             first=1;
                   6650:           } /*l12 */
                   6651:         } /* k12 */
                   6652:        } /*l1 */
                   6653:      }/* k1 */
                   6654:    }  /* loop on combination of covariates j1 */
                   6655:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6656:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6657:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6658:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6659:    free_vector(xp,1,npar);
                   6660:    fclose(ficresprob);
                   6661:    fclose(ficresprobcov);
                   6662:    fclose(ficresprobcor);
                   6663:    fflush(ficgp);
                   6664:    fflush(fichtmcov);
                   6665:  }
1.126     brouard  6666: 
                   6667: 
                   6668: /******************* Printing html file ***********/
1.201     brouard  6669: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6670:                  int lastpass, int stepm, int weightopt, char model[],\
                   6671:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6672:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6673:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6674:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6675:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6676: 
                   6677:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6678:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6679: </ul>");
1.237     brouard  6680:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6681: </ul>", model);
1.214     brouard  6682:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6683:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6684:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6685:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6686:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6687:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6688:    fprintf(fichtm,"\
                   6689:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6690:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6691:    fprintf(fichtm,"\
1.217     brouard  6692:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6693:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6694:    fprintf(fichtm,"\
1.126     brouard  6695:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6696:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6697:    fprintf(fichtm,"\
1.217     brouard  6698:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6699:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6700:    fprintf(fichtm,"\
1.211     brouard  6701:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6702:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6703:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6704:    if(prevfcast==1){
                   6705:      fprintf(fichtm,"\
                   6706:  - Prevalence projections by age and states:                           \
1.201     brouard  6707:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6708:    }
1.126     brouard  6709: 
                   6710: 
1.225     brouard  6711:    m=pow(2,cptcoveff);
1.222     brouard  6712:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6713: 
1.264     brouard  6714:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6715: 
                   6716:    jj1=0;
                   6717: 
                   6718:    fprintf(fichtm," \n<ul>");
                   6719:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6720:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6721:      if(m != 1 && TKresult[nres]!= k1)
                   6722:        continue;
                   6723:      jj1++;
                   6724:      if (cptcovn > 0) {
                   6725:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6726:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6727:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6728:        }
                   6729:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6730:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6731:        }
                   6732:        fprintf(fichtm,"\">");
                   6733:        
                   6734:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6735:        fprintf(fichtm,"************ Results for covariates");
                   6736:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6737:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6738:        }
                   6739:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6740:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6741:        }
                   6742:        if(invalidvarcomb[k1]){
                   6743:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6744:         continue;
                   6745:        }
                   6746:        fprintf(fichtm,"</a></li>");
                   6747:      } /* cptcovn >0 */
                   6748:    }
                   6749:      fprintf(fichtm," \n</ul>");
                   6750: 
1.222     brouard  6751:    jj1=0;
1.237     brouard  6752: 
                   6753:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6754:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6755:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6756:        continue;
1.220     brouard  6757: 
1.222     brouard  6758:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6759:      jj1++;
                   6760:      if (cptcovn > 0) {
1.264     brouard  6761:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6762:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6763:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6764:        }
                   6765:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6766:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6767:        }
                   6768:        fprintf(fichtm,"\"</a>");
                   6769:  
1.222     brouard  6770:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6771:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6772:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6773:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6774:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6775:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6776:        }
1.237     brouard  6777:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6778:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6779:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6780:       }
                   6781:        
1.230     brouard  6782:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6783:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6784:        if(invalidvarcomb[k1]){
                   6785:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6786:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6787:         continue;
                   6788:        }
                   6789:      }
                   6790:      /* aij, bij */
1.259     brouard  6791:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6792: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6793:      /* Pij */
1.241     brouard  6794:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6795: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6796:      /* Quasi-incidences */
                   6797:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6798:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6799:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6800: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6801: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6802:      /* Survival functions (period) in state j */
                   6803:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6804:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6805: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6806:      }
                   6807:      /* State specific survival functions (period) */
                   6808:      for(cpt=1; cpt<=nlstate;cpt++){
                   6809:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6810:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6811:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6812:      }
                   6813:      /* Period (stable) prevalence in each health state */
                   6814:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6815:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6816: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6817:      }
                   6818:      if(backcast==1){
                   6819:        /* Period (stable) back prevalence in each health state */
                   6820:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6821:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6822: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6823:        }
1.217     brouard  6824:      }
1.222     brouard  6825:      if(prevfcast==1){
                   6826:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6827:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6828:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6829: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6830:        }
                   6831:      }
1.268     brouard  6832:      if(backcast==1){
                   6833:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6834:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6835:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6836:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6837:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6838: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6839:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6840:        }
                   6841:      }
1.220     brouard  6842:         
1.222     brouard  6843:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6844:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6845: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6846:      }
                   6847:      /* } /\* end i1 *\/ */
                   6848:    }/* End k1 */
                   6849:    fprintf(fichtm,"</ul>");
1.126     brouard  6850: 
1.222     brouard  6851:    fprintf(fichtm,"\
1.126     brouard  6852: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6853:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6854:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6855: But because parameters are usually highly correlated (a higher incidence of disability \
                   6856: and a higher incidence of recovery can give very close observed transition) it might \
                   6857: be very useful to look not only at linear confidence intervals estimated from the \
                   6858: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6859: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6860: covariance matrix of the one-step probabilities. \
                   6861: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6862: 
1.222     brouard  6863:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6864:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6865:    fprintf(fichtm,"\
1.126     brouard  6866:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6867:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6868: 
1.222     brouard  6869:    fprintf(fichtm,"\
1.126     brouard  6870:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6871:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6872:    fprintf(fichtm,"\
1.126     brouard  6873:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6874:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6875:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6876:    fprintf(fichtm,"\
1.126     brouard  6877:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6878:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6879:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6880:    fprintf(fichtm,"\
1.128     brouard  6881:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6882:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6883:    fprintf(fichtm,"\
1.128     brouard  6884:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6885:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6886:    fprintf(fichtm,"\
1.126     brouard  6887:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6888:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6889: 
                   6890: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6891: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6892: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6893: /*     <br>",fileres,fileres,fileres,fileres); */
                   6894: /*  else  */
                   6895: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6896:    fflush(fichtm);
                   6897:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6898: 
1.225     brouard  6899:    m=pow(2,cptcoveff);
1.222     brouard  6900:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6901: 
1.222     brouard  6902:    jj1=0;
1.237     brouard  6903: 
1.241     brouard  6904:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6905:    for(k1=1; k1<=m;k1++){
1.253     brouard  6906:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6907:        continue;
1.222     brouard  6908:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6909:      jj1++;
1.126     brouard  6910:      if (cptcovn > 0) {
                   6911:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6912:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6913:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6914:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6915:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6916:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6917:       }
                   6918: 
1.126     brouard  6919:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6920: 
1.222     brouard  6921:        if(invalidvarcomb[k1]){
                   6922:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6923:         continue;
                   6924:        }
1.126     brouard  6925:      }
                   6926:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6927:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6928: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6929: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6930:      }
                   6931:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6932: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6933: true period expectancies (those weighted with period prevalences are also\
                   6934:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6935:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6936: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6937:      /* } /\* end i1 *\/ */
                   6938:    }/* End k1 */
1.241     brouard  6939:   }/* End nres */
1.222     brouard  6940:    fprintf(fichtm,"</ul>");
                   6941:    fflush(fichtm);
1.126     brouard  6942: }
                   6943: 
                   6944: /******************* Gnuplot file **************/
1.270     brouard  6945: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6946: 
                   6947:   char dirfileres[132],optfileres[132];
1.264     brouard  6948:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6949:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6950:   int lv=0, vlv=0, kl=0;
1.130     brouard  6951:   int ng=0;
1.201     brouard  6952:   int vpopbased;
1.223     brouard  6953:   int ioffset; /* variable offset for columns */
1.270     brouard  6954:   int iyearc=1; /* variable column for year of projection  */
                   6955:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  6956:   int nres=0; /* Index of resultline */
1.266     brouard  6957:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6958: 
1.126     brouard  6959: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6960: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6961: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6962: /*   } */
                   6963: 
                   6964:   /*#ifdef windows */
                   6965:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6966:   /*#endif */
1.225     brouard  6967:   m=pow(2,cptcoveff);
1.126     brouard  6968: 
1.274     brouard  6969:   /* diagram of the model */
                   6970:   fprintf(ficgp,"\n#Diagram of the model \n");
                   6971:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   6972:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   6973:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   6974: 
                   6975:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   6976:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   6977:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   6978:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   6979:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   6980:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   6981:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   6982: 
1.202     brouard  6983:   /* Contribution to likelihood */
                   6984:   /* Plot the probability implied in the likelihood */
1.223     brouard  6985:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6986:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6987:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6988:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6989: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6990:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6991: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6992:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6993:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6994:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6995:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6996:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6997:   for (i=1; i<= nlstate ; i ++) {
                   6998:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6999:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7000:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7001:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7002:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7003:     }
                   7004:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7005:   }
                   7006:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7007:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7008:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7009:   fprintf(ficgp,"\nset out;unset log\n");
                   7010:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7011: 
1.126     brouard  7012:   strcpy(dirfileres,optionfilefiname);
                   7013:   strcpy(optfileres,"vpl");
1.223     brouard  7014:   /* 1eme*/
1.238     brouard  7015:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7016:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7017:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7018:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7019:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7020:          continue;
                   7021:        /* We are interested in selected combination by the resultline */
1.246     brouard  7022:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7023:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7024:        strcpy(gplotlabel,"(");
1.238     brouard  7025:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7026:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7027:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7028:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7029:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7030:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7031:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7032:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7033:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7034:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7035:        }
                   7036:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7037:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7038:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7039:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7040:        }
                   7041:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7042:        /* printf("\n#\n"); */
1.238     brouard  7043:        fprintf(ficgp,"\n#\n");
                   7044:        if(invalidvarcomb[k1]){
1.260     brouard  7045:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7046:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7047:          continue;
                   7048:        }
1.235     brouard  7049:       
1.241     brouard  7050:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7051:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7052:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7053:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7054:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7055:       /* k1-1 error should be nres-1*/
1.238     brouard  7056:        for (i=1; i<= nlstate ; i ++) {
                   7057:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7058:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7059:        }
1.260     brouard  7060:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7061:        for (i=1; i<= nlstate ; i ++) {
                   7062:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7063:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7064:        } 
1.260     brouard  7065:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7066:        for (i=1; i<= nlstate ; i ++) {
                   7067:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7068:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7069:        }  
1.265     brouard  7070:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7071:        
                   7072:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7073:         if(cptcoveff ==0){
1.271     brouard  7074:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7075:        }else{
                   7076:          kl=0;
                   7077:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7078:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7079:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7080:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7081:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7082:            vlv= nbcode[Tvaraff[k]][lv];
                   7083:            kl++;
                   7084:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7085:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7086:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7087:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7088:            if(k==cptcoveff){
                   7089:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7090:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7091:            }else{
                   7092:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7093:              kl++;
                   7094:            }
                   7095:          } /* end covariate */
                   7096:        } /* end if no covariate */
                   7097: 
1.238     brouard  7098:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7099:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7100:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7101:          if(cptcoveff ==0){
1.245     brouard  7102:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7103:          }else{
                   7104:            kl=0;
                   7105:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7106:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7107:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7108:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7109:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7110:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7111:              kl++;
1.238     brouard  7112:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7113:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7114:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7115:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7116:              if(k==cptcoveff){
1.245     brouard  7117:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7118:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7119:              }else{
                   7120:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7121:                kl++;
                   7122:              }
                   7123:            } /* end covariate */
                   7124:          } /* end if no covariate */
1.268     brouard  7125:          if(backcast == 1){
                   7126:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7127:            /* k1-1 error should be nres-1*/
                   7128:            for (i=1; i<= nlstate ; i ++) {
                   7129:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7130:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7131:            }
1.271     brouard  7132:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7133:            for (i=1; i<= nlstate ; i ++) {
                   7134:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7135:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7136:            } 
1.272     brouard  7137:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 5,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7138:            for (i=1; i<= nlstate ; i ++) {
                   7139:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7140:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7141:            } 
1.274     brouard  7142:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7143:          } /* end if backprojcast */
1.238     brouard  7144:        } /* end if backcast */
1.264     brouard  7145:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7146:       } /* nres */
1.201     brouard  7147:     } /* k1 */
                   7148:   } /* cpt */
1.235     brouard  7149: 
                   7150:   
1.126     brouard  7151:   /*2 eme*/
1.238     brouard  7152:   for (k1=1; k1<= m ; k1 ++){  
                   7153:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7154:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7155:        continue;
                   7156:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7157:       strcpy(gplotlabel,"(");
1.238     brouard  7158:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7159:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7160:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7161:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7162:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7163:        vlv= nbcode[Tvaraff[k]][lv];
                   7164:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7165:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7166:       }
1.237     brouard  7167:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7168:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7169:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7170:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7171:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7172:       }
1.264     brouard  7173:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7174:       fprintf(ficgp,"\n#\n");
1.223     brouard  7175:       if(invalidvarcomb[k1]){
                   7176:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7177:        continue;
                   7178:       }
1.219     brouard  7179:                        
1.241     brouard  7180:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7181:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7182:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7183:        if(vpopbased==0){
1.238     brouard  7184:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7185:        }else
1.238     brouard  7186:          fprintf(ficgp,"\nreplot ");
                   7187:        for (i=1; i<= nlstate+1 ; i ++) {
                   7188:          k=2*i;
1.261     brouard  7189:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7190:          for (j=1; j<= nlstate+1 ; j ++) {
                   7191:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7192:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7193:          }   
                   7194:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7195:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7196:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7197:          for (j=1; j<= nlstate+1 ; j ++) {
                   7198:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7199:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7200:          }   
                   7201:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7202:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7203:          for (j=1; j<= nlstate+1 ; j ++) {
                   7204:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7205:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7206:          }   
                   7207:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7208:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7209:        } /* state */
                   7210:       } /* vpopbased */
1.264     brouard  7211:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7212:     } /* end nres */
                   7213:   } /* k1 end 2 eme*/
                   7214:        
                   7215:        
                   7216:   /*3eme*/
                   7217:   for (k1=1; k1<= m ; k1 ++){
                   7218:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7219:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7220:        continue;
                   7221: 
                   7222:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7223:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7224:        strcpy(gplotlabel,"(");
1.238     brouard  7225:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7226:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7227:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7228:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7229:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7230:          vlv= nbcode[Tvaraff[k]][lv];
                   7231:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7232:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7233:        }
                   7234:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7235:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7236:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7237:        }       
1.264     brouard  7238:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7239:        fprintf(ficgp,"\n#\n");
                   7240:        if(invalidvarcomb[k1]){
                   7241:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7242:          continue;
                   7243:        }
                   7244:                        
                   7245:        /*       k=2+nlstate*(2*cpt-2); */
                   7246:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7247:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7248:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7249:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7250: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7251:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7252:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7253:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7254:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7255:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7256:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7257:                                
1.238     brouard  7258:        */
                   7259:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7260:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7261:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7262:                                
1.238     brouard  7263:        } 
1.261     brouard  7264:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7265:       }
1.264     brouard  7266:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7267:     } /* end nres */
                   7268:   } /* end kl 3eme */
1.126     brouard  7269:   
1.223     brouard  7270:   /* 4eme */
1.201     brouard  7271:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7272:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7273:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7274:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7275:        continue;
1.238     brouard  7276:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7277:        strcpy(gplotlabel,"(");
1.238     brouard  7278:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7279:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7280:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7281:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7282:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7283:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7284:          vlv= nbcode[Tvaraff[k]][lv];
                   7285:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7286:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7287:        }
                   7288:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7289:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7290:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7291:        }       
1.264     brouard  7292:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7293:        fprintf(ficgp,"\n#\n");
                   7294:        if(invalidvarcomb[k1]){
                   7295:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7296:          continue;
1.223     brouard  7297:        }
1.238     brouard  7298:       
1.241     brouard  7299:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7300:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7301:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7302: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7303:        k=3;
                   7304:        for (i=1; i<= nlstate ; i ++){
                   7305:          if(i==1){
                   7306:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7307:          }else{
                   7308:            fprintf(ficgp,", '' ");
                   7309:          }
                   7310:          l=(nlstate+ndeath)*(i-1)+1;
                   7311:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7312:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7313:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7314:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7315:        } /* nlstate */
1.264     brouard  7316:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7317:       } /* end cpt state*/ 
                   7318:     } /* end nres */
                   7319:   } /* end covariate k1 */  
                   7320: 
1.220     brouard  7321: /* 5eme */
1.201     brouard  7322:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7323:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7324:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7325:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7326:        continue;
1.238     brouard  7327:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7328:        strcpy(gplotlabel,"(");
1.238     brouard  7329:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7330:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7331:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7332:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7333:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7334:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7335:          vlv= nbcode[Tvaraff[k]][lv];
                   7336:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7337:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7338:        }
                   7339:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7340:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7341:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7342:        }       
1.264     brouard  7343:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7344:        fprintf(ficgp,"\n#\n");
                   7345:        if(invalidvarcomb[k1]){
                   7346:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7347:          continue;
                   7348:        }
1.227     brouard  7349:       
1.241     brouard  7350:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7351:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7352:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7353: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7354:        k=3;
                   7355:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7356:          if(j==1)
                   7357:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7358:          else
                   7359:            fprintf(ficgp,", '' ");
                   7360:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7361:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7362:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7363:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7364:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7365:        } /* nlstate */
                   7366:        fprintf(ficgp,", '' ");
                   7367:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7368:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7369:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7370:          if(j < nlstate)
                   7371:            fprintf(ficgp,"$%d +",k+l);
                   7372:          else
                   7373:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7374:        }
1.264     brouard  7375:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7376:       } /* end cpt state*/ 
                   7377:     } /* end covariate */  
                   7378:   } /* end nres */
1.227     brouard  7379:   
1.220     brouard  7380: /* 6eme */
1.202     brouard  7381:   /* CV preval stable (period) for each covariate */
1.237     brouard  7382:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7383:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7384:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7385:       continue;
1.255     brouard  7386:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7387:       strcpy(gplotlabel,"(");      
1.211     brouard  7388:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7389:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7390:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7391:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7392:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7393:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7394:        vlv= nbcode[Tvaraff[k]][lv];
                   7395:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7396:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7397:       }
1.237     brouard  7398:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7399:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7400:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7401:       }        
1.264     brouard  7402:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7403:       fprintf(ficgp,"\n#\n");
1.223     brouard  7404:       if(invalidvarcomb[k1]){
1.227     brouard  7405:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7406:        continue;
1.223     brouard  7407:       }
1.227     brouard  7408:       
1.241     brouard  7409:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7410:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7411:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7412: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7413:       k=3; /* Offset */
1.255     brouard  7414:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7415:        if(i==1)
                   7416:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7417:        else
                   7418:          fprintf(ficgp,", '' ");
1.255     brouard  7419:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7420:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7421:        for (j=2; j<= nlstate ; j ++)
                   7422:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7423:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7424:       } /* nlstate */
1.264     brouard  7425:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7426:     } /* end cpt state*/ 
                   7427:   } /* end covariate */  
1.227     brouard  7428:   
                   7429:   
1.220     brouard  7430: /* 7eme */
1.218     brouard  7431:   if(backcast == 1){
1.217     brouard  7432:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7433:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7434:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7435:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7436:        continue;
1.268     brouard  7437:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7438:        strcpy(gplotlabel,"(");      
                   7439:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7440:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7441:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7442:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7443:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7444:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7445:          vlv= nbcode[Tvaraff[k]][lv];
                   7446:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7447:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7448:        }
1.237     brouard  7449:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7450:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7451:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7452:        }       
1.264     brouard  7453:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7454:        fprintf(ficgp,"\n#\n");
                   7455:        if(invalidvarcomb[k1]){
                   7456:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7457:          continue;
                   7458:        }
                   7459:        
1.241     brouard  7460:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7461:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7462:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7463: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7464:        k=3; /* Offset */
1.268     brouard  7465:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7466:          if(i==1)
                   7467:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7468:          else
                   7469:            fprintf(ficgp,", '' ");
                   7470:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7471:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7472:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7473:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7474:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7475:          /* for (j=2; j<= nlstate ; j ++) */
                   7476:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7477:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7478:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7479:        } /* nlstate */
1.264     brouard  7480:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7481:       } /* end cpt state*/ 
                   7482:     } /* end covariate */  
                   7483:   } /* End if backcast */
                   7484:   
1.223     brouard  7485:   /* 8eme */
1.218     brouard  7486:   if(prevfcast==1){
                   7487:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7488:     
1.237     brouard  7489:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7490:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7491:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7492:        continue;
1.211     brouard  7493:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7494:        strcpy(gplotlabel,"(");      
1.227     brouard  7495:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7496:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7497:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7498:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7499:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7500:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7501:          vlv= nbcode[Tvaraff[k]][lv];
                   7502:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7503:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7504:        }
1.237     brouard  7505:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7506:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7507:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7508:        }       
1.264     brouard  7509:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7510:        fprintf(ficgp,"\n#\n");
                   7511:        if(invalidvarcomb[k1]){
                   7512:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7513:          continue;
                   7514:        }
                   7515:        
                   7516:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7517:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7518:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7519:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7520: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7521: 
                   7522:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7523:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7524:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7525:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7526:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7527:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7528:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7529:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7530:          if(i==istart){
1.227     brouard  7531:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7532:          }else{
                   7533:            fprintf(ficgp,",\\\n '' ");
                   7534:          }
                   7535:          if(cptcoveff ==0){ /* No covariate */
                   7536:            ioffset=2; /* Age is in 2 */
                   7537:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7538:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7539:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7540:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7541:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7542:            if(i==nlstate+1){
1.270     brouard  7543:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7544:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7545:              fprintf(ficgp,",\\\n '' ");
                   7546:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7547:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7548:                     offyear,                           \
1.268     brouard  7549:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7550:            }else
1.227     brouard  7551:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7552:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7553:          }else{ /* more than 2 covariates */
1.270     brouard  7554:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7555:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7556:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7557:            iyearc=ioffset-1;
                   7558:            iagec=ioffset;
1.227     brouard  7559:            fprintf(ficgp," u %d:(",ioffset); 
                   7560:            kl=0;
                   7561:            strcpy(gplotcondition,"(");
                   7562:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7563:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7564:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7565:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7566:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7567:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7568:              kl++;
                   7569:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7570:              kl++;
                   7571:              if(k <cptcoveff && cptcoveff>1)
                   7572:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7573:            }
                   7574:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7575:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7576:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7577:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7578:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7579:            if(i==nlstate+1){
1.270     brouard  7580:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7581:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7582:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7583:              fprintf(ficgp," u %d:(",iagec); 
                   7584:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7585:                      iyearc, iagec, offyear,                           \
                   7586:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7587: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7588:            }else{
                   7589:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7590:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7591:            }
                   7592:          } /* end if covariate */
                   7593:        } /* nlstate */
1.264     brouard  7594:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7595:       } /* end cpt state*/
                   7596:     } /* end covariate */
                   7597:   } /* End if prevfcast */
1.227     brouard  7598:   
1.268     brouard  7599:   if(backcast==1){
                   7600:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7601:     
                   7602:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7603:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7604:       if(m != 1 && TKresult[nres]!= k1)
                   7605:        continue;
                   7606:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7607:        strcpy(gplotlabel,"(");      
                   7608:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7609:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7610:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7611:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7612:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7613:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7614:          vlv= nbcode[Tvaraff[k]][lv];
                   7615:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7616:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7617:        }
                   7618:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7619:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7620:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7621:        }       
                   7622:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7623:        fprintf(ficgp,"\n#\n");
                   7624:        if(invalidvarcomb[k1]){
                   7625:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7626:          continue;
                   7627:        }
                   7628:        
                   7629:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7630:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7631:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7632:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7633: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7634: 
                   7635:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7636:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7637:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7638:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7639:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7640:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7641:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7642:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7643:          if(i==istart){
                   7644:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7645:          }else{
                   7646:            fprintf(ficgp,",\\\n '' ");
                   7647:          }
                   7648:          if(cptcoveff ==0){ /* No covariate */
                   7649:            ioffset=2; /* Age is in 2 */
                   7650:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7651:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7652:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7653:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7654:            fprintf(ficgp," u %d:(", ioffset); 
                   7655:            if(i==nlstate+1){
1.270     brouard  7656:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7657:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7658:              fprintf(ficgp,",\\\n '' ");
                   7659:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7660:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7661:                     offbyear,                          \
                   7662:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7663:            }else
                   7664:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7665:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7666:          }else{ /* more than 2 covariates */
1.270     brouard  7667:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7668:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7669:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7670:            iyearc=ioffset-1;
                   7671:            iagec=ioffset;
1.268     brouard  7672:            fprintf(ficgp," u %d:(",ioffset); 
                   7673:            kl=0;
                   7674:            strcpy(gplotcondition,"(");
                   7675:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7676:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7677:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7678:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7679:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7680:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7681:              kl++;
                   7682:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7683:              kl++;
                   7684:              if(k <cptcoveff && cptcoveff>1)
                   7685:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7686:            }
                   7687:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7688:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7689:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7690:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7691:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7692:            if(i==nlstate+1){
1.270     brouard  7693:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7694:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7695:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7696:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7697:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7698:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7699:                      iyearc,iagec,offbyear,                            \
                   7700:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7701: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7702:            }else{
                   7703:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7704:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7705:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7706:            }
                   7707:          } /* end if covariate */
                   7708:        } /* nlstate */
                   7709:        fprintf(ficgp,"\nset out; unset label;\n");
                   7710:       } /* end cpt state*/
                   7711:     } /* end covariate */
                   7712:   } /* End if backcast */
                   7713:   
1.227     brouard  7714:   
1.238     brouard  7715:   /* 9eme writing MLE parameters */
                   7716:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7717:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7718:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7719:     for(k=1; k <=(nlstate+ndeath); k++){
                   7720:       if (k != i) {
1.227     brouard  7721:        fprintf(ficgp,"#   current state %d\n",k);
                   7722:        for(j=1; j <=ncovmodel; j++){
                   7723:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7724:          jk++; 
                   7725:        }
                   7726:        fprintf(ficgp,"\n");
1.126     brouard  7727:       }
                   7728:     }
1.223     brouard  7729:   }
1.187     brouard  7730:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7731:   
1.145     brouard  7732:   /*goto avoid;*/
1.238     brouard  7733:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7734:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7735:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7736:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7737:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7738:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7739:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7740:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7741:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7742:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7743:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7744:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7745:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7746:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7747:   fprintf(ficgp,"#\n");
1.223     brouard  7748:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7749:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7750:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7751:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7752:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7753:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7754:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7755:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7756:        continue;
1.264     brouard  7757:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7758:       strcpy(gplotlabel,"(");
                   7759:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7760:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7761:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7762:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7763:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7764:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7765:        vlv= nbcode[Tvaraff[k]][lv];
                   7766:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7767:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7768:       }
1.237     brouard  7769:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7770:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7771:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7772:       }        
1.264     brouard  7773:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7774:       fprintf(ficgp,"\n#\n");
1.264     brouard  7775:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7776:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7777:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7778:       if (ng==1){
                   7779:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7780:        fprintf(ficgp,"\nunset log y");
                   7781:       }else if (ng==2){
                   7782:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7783:        fprintf(ficgp,"\nset log y");
                   7784:       }else if (ng==3){
                   7785:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7786:        fprintf(ficgp,"\nset log y");
                   7787:       }else
                   7788:        fprintf(ficgp,"\nunset title ");
                   7789:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7790:       i=1;
                   7791:       for(k2=1; k2<=nlstate; k2++) {
                   7792:        k3=i;
                   7793:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7794:          if (k != k2){
                   7795:            switch( ng) {
                   7796:            case 1:
                   7797:              if(nagesqr==0)
                   7798:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7799:              else /* nagesqr =1 */
                   7800:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7801:              break;
                   7802:            case 2: /* ng=2 */
                   7803:              if(nagesqr==0)
                   7804:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7805:              else /* nagesqr =1 */
                   7806:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7807:              break;
                   7808:            case 3:
                   7809:              if(nagesqr==0)
                   7810:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7811:              else /* nagesqr =1 */
                   7812:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7813:              break;
                   7814:            }
                   7815:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7816:            ijp=1; /* product no age */
                   7817:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7818:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7819:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7820:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7821:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7822:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7823:                    if(DummyV[j]==0){
                   7824:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7825:                    }else{ /* quantitative */
                   7826:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7827:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7828:                    }
                   7829:                    ij++;
1.237     brouard  7830:                  }
1.268     brouard  7831:                } 
                   7832:              }else if(cptcovprod >0){
                   7833:                if(j==Tprod[ijp]) { /* */ 
                   7834:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7835:                  if(ijp <=cptcovprod) { /* Product */
                   7836:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7837:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7838:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7839:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7840:                      }else{ /* Vn is dummy and Vm is quanti */
                   7841:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7842:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7843:                      }
                   7844:                    }else{ /* Vn*Vm Vn is quanti */
                   7845:                      if(DummyV[Tvard[ijp][2]]==0){
                   7846:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7847:                      }else{ /* Both quanti */
                   7848:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7849:                      }
1.237     brouard  7850:                    }
1.268     brouard  7851:                    ijp++;
1.237     brouard  7852:                  }
1.268     brouard  7853:                } /* end Tprod */
1.237     brouard  7854:              } else{  /* simple covariate */
1.264     brouard  7855:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7856:                if(Dummy[j]==0){
                   7857:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7858:                }else{ /* quantitative */
                   7859:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7860:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7861:                }
1.237     brouard  7862:              } /* end simple */
                   7863:            } /* end j */
1.223     brouard  7864:          }else{
                   7865:            i=i-ncovmodel;
                   7866:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7867:              fprintf(ficgp," (1.");
                   7868:          }
1.227     brouard  7869:          
1.223     brouard  7870:          if(ng != 1){
                   7871:            fprintf(ficgp,")/(1");
1.227     brouard  7872:            
1.264     brouard  7873:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7874:              if(nagesqr==0)
1.264     brouard  7875:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7876:              else /* nagesqr =1 */
1.264     brouard  7877:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7878:               
1.223     brouard  7879:              ij=1;
                   7880:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7881:                 if(cptcovage >0){ 
                   7882:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7883:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7884:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7885:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7886:                       ij++;
                   7887:                     }
                   7888:                   }
                   7889:                 }else
                   7890:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7891:              }
                   7892:              fprintf(ficgp,")");
                   7893:            }
                   7894:            fprintf(ficgp,")");
                   7895:            if(ng ==2)
1.275   ! brouard  7896:              fprintf(ficgp," w l lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7897:            else /* ng= 3 */
1.275   ! brouard  7898:              fprintf(ficgp," w l lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7899:          }else{ /* end ng <> 1 */
                   7900:            if( k !=k2) /* logit p11 is hard to draw */
1.275   ! brouard  7901:              fprintf(ficgp," w l lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7902:          }
                   7903:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7904:            fprintf(ficgp,",");
                   7905:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7906:            fprintf(ficgp,",");
                   7907:          i=i+ncovmodel;
                   7908:        } /* end k */
                   7909:       } /* end k2 */
1.264     brouard  7910:       fprintf(ficgp,"\n set out; unset label;\n");
                   7911:     } /* end k1 */
1.223     brouard  7912:   } /* end ng */
                   7913:   /* avoid: */
                   7914:   fflush(ficgp); 
1.126     brouard  7915: }  /* end gnuplot */
                   7916: 
                   7917: 
                   7918: /*************** Moving average **************/
1.219     brouard  7919: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7920:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7921:    
1.222     brouard  7922:    int i, cpt, cptcod;
                   7923:    int modcovmax =1;
                   7924:    int mobilavrange, mob;
                   7925:    int iage=0;
                   7926: 
1.266     brouard  7927:    double sum=0., sumr=0.;
1.222     brouard  7928:    double age;
1.266     brouard  7929:    double *sumnewp, *sumnewm, *sumnewmr;
                   7930:    double *agemingood, *agemaxgood; 
                   7931:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7932:   
                   7933:   
1.225     brouard  7934:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7935:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7936: 
                   7937:    sumnewp = vector(1,ncovcombmax);
                   7938:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7939:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7940:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7941:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7942:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7943:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7944: 
                   7945:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7946:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7947:      sumnewp[cptcod]=0.;
1.266     brouard  7948:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7949:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7950:    }
                   7951:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7952:   
1.266     brouard  7953:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7954:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7955:      else mobilavrange=mobilav;
                   7956:      for (age=bage; age<=fage; age++)
                   7957:        for (i=1; i<=nlstate;i++)
                   7958:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7959:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7960:      /* We keep the original values on the extreme ages bage, fage and for 
                   7961:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7962:        we use a 5 terms etc. until the borders are no more concerned. 
                   7963:      */ 
                   7964:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7965:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7966:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7967:           sumnewm[cptcod]=0.;
                   7968:           for (i=1; i<=nlstate;i++){
1.222     brouard  7969:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7970:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7971:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7972:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7973:             }
                   7974:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7975:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7976:           } /* end i */
                   7977:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7978:         } /* end cptcod */
1.222     brouard  7979:        }/* end age */
                   7980:      }/* end mob */
1.266     brouard  7981:    }else{
                   7982:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7983:      return -1;
1.266     brouard  7984:    }
                   7985: 
                   7986:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7987:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7988:      if(invalidvarcomb[cptcod]){
                   7989:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7990:        continue;
                   7991:      }
1.219     brouard  7992: 
1.266     brouard  7993:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7994:        sumnewm[cptcod]=0.;
                   7995:        sumnewmr[cptcod]=0.;
                   7996:        for (i=1; i<=nlstate;i++){
                   7997:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7998:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7999:        }
                   8000:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8001:         agemingoodr[cptcod]=age;
                   8002:        }
                   8003:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8004:           agemingood[cptcod]=age;
                   8005:        }
                   8006:      } /* age */
                   8007:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8008:        sumnewm[cptcod]=0.;
1.266     brouard  8009:        sumnewmr[cptcod]=0.;
1.222     brouard  8010:        for (i=1; i<=nlstate;i++){
                   8011:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8012:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8013:        }
                   8014:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8015:         agemaxgoodr[cptcod]=age;
1.222     brouard  8016:        }
                   8017:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8018:         agemaxgood[cptcod]=age;
                   8019:        }
                   8020:      } /* age */
                   8021:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8022:      /* but they will change */
                   8023:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8024:        sumnewm[cptcod]=0.;
                   8025:        sumnewmr[cptcod]=0.;
                   8026:        for (i=1; i<=nlstate;i++){
                   8027:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8028:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8029:        }
                   8030:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8031:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8032:           agemaxgoodr[cptcod]=age;  /* age min */
                   8033:           for (i=1; i<=nlstate;i++)
                   8034:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8035:         }else{ /* bad we change the value with the values of good ages */
                   8036:           for (i=1; i<=nlstate;i++){
                   8037:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8038:           } /* i */
                   8039:         } /* end bad */
                   8040:        }else{
                   8041:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8042:           agemaxgood[cptcod]=age;
                   8043:         }else{ /* bad we change the value with the values of good ages */
                   8044:           for (i=1; i<=nlstate;i++){
                   8045:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8046:           } /* i */
                   8047:         } /* end bad */
                   8048:        }/* end else */
                   8049:        sum=0.;sumr=0.;
                   8050:        for (i=1; i<=nlstate;i++){
                   8051:         sum+=mobaverage[(int)age][i][cptcod];
                   8052:         sumr+=probs[(int)age][i][cptcod];
                   8053:        }
                   8054:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8055:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8056:        } /* end bad */
                   8057:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8058:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8059:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8060:        } /* end bad */
                   8061:      }/* age */
1.266     brouard  8062: 
                   8063:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8064:        sumnewm[cptcod]=0.;
1.266     brouard  8065:        sumnewmr[cptcod]=0.;
1.222     brouard  8066:        for (i=1; i<=nlstate;i++){
                   8067:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8068:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8069:        } 
                   8070:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8071:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8072:           agemingoodr[cptcod]=age;
                   8073:           for (i=1; i<=nlstate;i++)
                   8074:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8075:         }else{ /* bad we change the value with the values of good ages */
                   8076:           for (i=1; i<=nlstate;i++){
                   8077:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8078:           } /* i */
                   8079:         } /* end bad */
                   8080:        }else{
                   8081:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8082:           agemingood[cptcod]=age;
                   8083:         }else{ /* bad */
                   8084:           for (i=1; i<=nlstate;i++){
                   8085:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8086:           } /* i */
                   8087:         } /* end bad */
                   8088:        }/* end else */
                   8089:        sum=0.;sumr=0.;
                   8090:        for (i=1; i<=nlstate;i++){
                   8091:         sum+=mobaverage[(int)age][i][cptcod];
                   8092:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8093:        }
1.266     brouard  8094:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8095:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8096:        } /* end bad */
                   8097:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8098:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8099:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8100:        } /* end bad */
                   8101:      }/* age */
1.266     brouard  8102: 
1.222     brouard  8103:                
                   8104:      for (age=bage; age<=fage; age++){
1.235     brouard  8105:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8106:        sumnewp[cptcod]=0.;
                   8107:        sumnewm[cptcod]=0.;
                   8108:        for (i=1; i<=nlstate;i++){
                   8109:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8110:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8111:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8112:        }
                   8113:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8114:      }
                   8115:      /* printf("\n"); */
                   8116:      /* } */
1.266     brouard  8117: 
1.222     brouard  8118:      /* brutal averaging */
1.266     brouard  8119:      /* for (i=1; i<=nlstate;i++){ */
                   8120:      /*   for (age=1; age<=bage; age++){ */
                   8121:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8122:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8123:      /*   }     */
                   8124:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8125:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8126:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8127:      /*   } */
                   8128:      /* } /\* end i status *\/ */
                   8129:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8130:      /*   for (age=1; age<=AGESUP; age++){ */
                   8131:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8132:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8133:      /*   } */
                   8134:      /* } */
1.222     brouard  8135:    }/* end cptcod */
1.266     brouard  8136:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8137:    free_vector(agemaxgood,1, ncovcombmax);
                   8138:    free_vector(agemingood,1, ncovcombmax);
                   8139:    free_vector(agemingoodr,1, ncovcombmax);
                   8140:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8141:    free_vector(sumnewm,1, ncovcombmax);
                   8142:    free_vector(sumnewp,1, ncovcombmax);
                   8143:    return 0;
                   8144:  }/* End movingaverage */
1.218     brouard  8145:  
1.126     brouard  8146: 
                   8147: /************** Forecasting ******************/
1.269     brouard  8148:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8149:   /* proj1, year, month, day of starting projection 
                   8150:      agemin, agemax range of age
                   8151:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8152:      anproj2 year of en of projection (same day and month as proj1).
                   8153:   */
1.267     brouard  8154:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8155:   double agec; /* generic age */
                   8156:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8157:   double *popeffectif,*popcount;
                   8158:   double ***p3mat;
1.218     brouard  8159:   /* double ***mobaverage; */
1.126     brouard  8160:   char fileresf[FILENAMELENGTH];
                   8161: 
                   8162:   agelim=AGESUP;
1.211     brouard  8163:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8164:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8165:      We still use firstpass and lastpass as another selection.
                   8166:   */
1.214     brouard  8167:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8168:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8169:  
1.201     brouard  8170:   strcpy(fileresf,"F_"); 
                   8171:   strcat(fileresf,fileresu);
1.126     brouard  8172:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8173:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8174:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8175:   }
1.235     brouard  8176:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8177:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8178: 
1.225     brouard  8179:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8180: 
                   8181: 
                   8182:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8183:   if (stepm<=12) stepsize=1;
                   8184:   if(estepm < stepm){
                   8185:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8186:   }
1.270     brouard  8187:   else{
                   8188:     hstepm=estepm;   
                   8189:   }
                   8190:   if(estepm > stepm){ /* Yes every two year */
                   8191:     stepsize=2;
                   8192:   }
1.126     brouard  8193: 
                   8194:   hstepm=hstepm/stepm; 
                   8195:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8196:                                fractional in yp1 */
                   8197:   anprojmean=yp;
                   8198:   yp2=modf((yp1*12),&yp);
                   8199:   mprojmean=yp;
                   8200:   yp1=modf((yp2*30.5),&yp);
                   8201:   jprojmean=yp;
                   8202:   if(jprojmean==0) jprojmean=1;
                   8203:   if(mprojmean==0) jprojmean=1;
                   8204: 
1.227     brouard  8205:   i1=pow(2,cptcoveff);
1.126     brouard  8206:   if (cptcovn < 1){i1=1;}
                   8207:   
                   8208:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8209:   
                   8210:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8211:   
1.126     brouard  8212: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8213:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8214:   for(k=1; k<=i1;k++){
1.253     brouard  8215:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8216:       continue;
1.227     brouard  8217:     if(invalidvarcomb[k]){
                   8218:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8219:       continue;
                   8220:     }
                   8221:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8222:     for(j=1;j<=cptcoveff;j++) {
                   8223:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8224:     }
1.235     brouard  8225:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8226:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8227:     }
1.227     brouard  8228:     fprintf(ficresf," yearproj age");
                   8229:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8230:       for(i=1; i<=nlstate;i++)               
                   8231:        fprintf(ficresf," p%d%d",i,j);
                   8232:       fprintf(ficresf," wp.%d",j);
                   8233:     }
                   8234:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8235:       fprintf(ficresf,"\n");
                   8236:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8237:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8238:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8239:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8240:        nhstepm = nhstepm/hstepm; 
                   8241:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8242:        oldm=oldms;savm=savms;
1.268     brouard  8243:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8244:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8245:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8246:        for (h=0; h<=nhstepm; h++){
                   8247:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8248:            break;
                   8249:          }
                   8250:        }
                   8251:        fprintf(ficresf,"\n");
                   8252:        for(j=1;j<=cptcoveff;j++) 
                   8253:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8254:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8255:        
                   8256:        for(j=1; j<=nlstate+ndeath;j++) {
                   8257:          ppij=0.;
                   8258:          for(i=1; i<=nlstate;i++) {
                   8259:            /* if (mobilav>=1)  */
1.269     brouard  8260:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8261:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8262:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8263:            /* } */
                   8264:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8265:          } /* end i */
                   8266:          fprintf(ficresf," %.3f", ppij);
                   8267:        }/* end j */
1.227     brouard  8268:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8269:       } /* end agec */
1.266     brouard  8270:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8271:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8272:     } /* end yearp */
                   8273:   } /* end  k */
1.219     brouard  8274:        
1.126     brouard  8275:   fclose(ficresf);
1.215     brouard  8276:   printf("End of Computing forecasting \n");
                   8277:   fprintf(ficlog,"End of Computing forecasting\n");
                   8278: 
1.126     brouard  8279: }
                   8280: 
1.269     brouard  8281: /************** Back Forecasting ******************/
                   8282:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8283:   /* back1, year, month, day of starting backection
                   8284:      agemin, agemax range of age
                   8285:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8286:      anback2 year of end of backprojection (same day and month as back1).
                   8287:      prevacurrent and prev are prevalences.
1.267     brouard  8288:   */
                   8289:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8290:   double agec; /* generic age */
1.268     brouard  8291:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8292:   double *popeffectif,*popcount;
                   8293:   double ***p3mat;
                   8294:   /* double ***mobaverage; */
                   8295:   char fileresfb[FILENAMELENGTH];
                   8296:  
1.268     brouard  8297:   agelim=AGEINF;
1.267     brouard  8298:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8299:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8300:      We still use firstpass and lastpass as another selection.
                   8301:   */
                   8302:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8303:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8304: 
                   8305:   /*Do we need to compute prevalence again?*/
                   8306: 
                   8307:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8308:   
                   8309:   strcpy(fileresfb,"FB_");
                   8310:   strcat(fileresfb,fileresu);
                   8311:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8312:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8313:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8314:   }
                   8315:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8316:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8317:   
                   8318:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8319:   
                   8320:    
                   8321:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8322:   if (stepm<=12) stepsize=1;
                   8323:   if(estepm < stepm){
                   8324:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8325:   }
1.270     brouard  8326:   else{
                   8327:     hstepm=estepm;   
                   8328:   }
                   8329:   if(estepm >= stepm){ /* Yes every two year */
                   8330:     stepsize=2;
                   8331:   }
1.267     brouard  8332:   
                   8333:   hstepm=hstepm/stepm;
                   8334:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8335:                                fractional in yp1 */
                   8336:   anprojmean=yp;
                   8337:   yp2=modf((yp1*12),&yp);
                   8338:   mprojmean=yp;
                   8339:   yp1=modf((yp2*30.5),&yp);
                   8340:   jprojmean=yp;
                   8341:   if(jprojmean==0) jprojmean=1;
                   8342:   if(mprojmean==0) jprojmean=1;
                   8343:   
                   8344:   i1=pow(2,cptcoveff);
                   8345:   if (cptcovn < 1){i1=1;}
                   8346:   
                   8347:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8348:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8349:   
                   8350:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8351:   
                   8352:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8353:   for(k=1; k<=i1;k++){
                   8354:     if(i1 != 1 && TKresult[nres]!= k)
                   8355:       continue;
                   8356:     if(invalidvarcomb[k]){
                   8357:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8358:       continue;
                   8359:     }
1.268     brouard  8360:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8361:     for(j=1;j<=cptcoveff;j++) {
                   8362:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8363:     }
                   8364:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8365:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8366:     }
                   8367:     fprintf(ficresfb," yearbproj age");
                   8368:     for(j=1; j<=nlstate+ndeath;j++){
                   8369:       for(i=1; i<=nlstate;i++)
1.268     brouard  8370:        fprintf(ficresfb," b%d%d",i,j);
                   8371:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8372:     }
                   8373:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8374:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8375:       fprintf(ficresfb,"\n");
                   8376:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8377:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8378:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8379:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8380:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8381:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8382:        nhstepm = nhstepm/hstepm;
                   8383:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8384:        oldm=oldms;savm=savms;
1.268     brouard  8385:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8386:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8387:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8388:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8389:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8390:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8391:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8392:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8393:            break;
                   8394:          }
                   8395:        }
                   8396:        fprintf(ficresfb,"\n");
                   8397:        for(j=1;j<=cptcoveff;j++)
                   8398:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8399:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8400:        for(i=1; i<=nlstate+ndeath;i++) {
                   8401:          ppij=0.;ppi=0.;
                   8402:          for(j=1; j<=nlstate;j++) {
                   8403:            /* if (mobilav==1) */
1.269     brouard  8404:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8405:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8406:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8407:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8408:              /* else { */
                   8409:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8410:              /* } */
1.268     brouard  8411:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8412:          } /* end j */
                   8413:          if(ppi <0.99){
                   8414:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8415:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8416:          }
                   8417:          fprintf(ficresfb," %.3f", ppij);
                   8418:        }/* end j */
1.267     brouard  8419:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8420:       } /* end agec */
                   8421:     } /* end yearp */
                   8422:   } /* end k */
1.217     brouard  8423:   
1.267     brouard  8424:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8425:   
1.267     brouard  8426:   fclose(ficresfb);
                   8427:   printf("End of Computing Back forecasting \n");
                   8428:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8429:        
1.267     brouard  8430: }
1.217     brouard  8431: 
1.269     brouard  8432: /* Variance of prevalence limit: varprlim */
                   8433:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8434:     /*------- Variance of period (stable) prevalence------*/   
                   8435:  
                   8436:    char fileresvpl[FILENAMELENGTH];  
                   8437:    FILE *ficresvpl;
                   8438:    double **oldm, **savm;
                   8439:    double **varpl; /* Variances of prevalence limits by age */   
                   8440:    int i1, k, nres, j ;
                   8441:    
                   8442:     strcpy(fileresvpl,"VPL_");
                   8443:     strcat(fileresvpl,fileresu);
                   8444:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8445:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8446:       exit(0);
                   8447:     }
                   8448:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8449:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8450:     
                   8451:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8452:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8453:     
                   8454:     i1=pow(2,cptcoveff);
                   8455:     if (cptcovn < 1){i1=1;}
                   8456: 
                   8457:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8458:     for(k=1; k<=i1;k++){
                   8459:       if(i1 != 1 && TKresult[nres]!= k)
                   8460:        continue;
                   8461:       fprintf(ficresvpl,"\n#****** ");
                   8462:       printf("\n#****** ");
                   8463:       fprintf(ficlog,"\n#****** ");
                   8464:       for(j=1;j<=cptcoveff;j++) {
                   8465:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8466:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8467:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8468:       }
                   8469:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8470:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8471:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8472:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8473:       }        
                   8474:       fprintf(ficresvpl,"******\n");
                   8475:       printf("******\n");
                   8476:       fprintf(ficlog,"******\n");
                   8477:       
                   8478:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8479:       oldm=oldms;savm=savms;
                   8480:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8481:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8482:       /*}*/
                   8483:     }
                   8484:     
                   8485:     fclose(ficresvpl);
                   8486:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8487:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8488: 
                   8489:  }
                   8490: /* Variance of back prevalence: varbprlim */
                   8491:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8492:       /*------- Variance of back (stable) prevalence------*/
                   8493: 
                   8494:    char fileresvbl[FILENAMELENGTH];  
                   8495:    FILE  *ficresvbl;
                   8496: 
                   8497:    double **oldm, **savm;
                   8498:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8499:    int i1, k, nres, j ;
                   8500: 
                   8501:    strcpy(fileresvbl,"VBL_");
                   8502:    strcat(fileresvbl,fileresu);
                   8503:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8504:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8505:      exit(0);
                   8506:    }
                   8507:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8508:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8509:    
                   8510:    
                   8511:    i1=pow(2,cptcoveff);
                   8512:    if (cptcovn < 1){i1=1;}
                   8513:    
                   8514:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8515:      for(k=1; k<=i1;k++){
                   8516:        if(i1 != 1 && TKresult[nres]!= k)
                   8517:         continue;
                   8518:        fprintf(ficresvbl,"\n#****** ");
                   8519:        printf("\n#****** ");
                   8520:        fprintf(ficlog,"\n#****** ");
                   8521:        for(j=1;j<=cptcoveff;j++) {
                   8522:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8523:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8524:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8525:        }
                   8526:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8527:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8528:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8529:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8530:        }
                   8531:        fprintf(ficresvbl,"******\n");
                   8532:        printf("******\n");
                   8533:        fprintf(ficlog,"******\n");
                   8534:        
                   8535:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8536:        oldm=oldms;savm=savms;
                   8537:        
                   8538:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8539:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8540:        /*}*/
                   8541:      }
                   8542:    
                   8543:    fclose(ficresvbl);
                   8544:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8545:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8546: 
                   8547:  } /* End of varbprlim */
                   8548: 
1.126     brouard  8549: /************** Forecasting *****not tested NB*************/
1.227     brouard  8550: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8551:   
1.227     brouard  8552: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8553: /*   int *popage; */
                   8554: /*   double calagedatem, agelim, kk1, kk2; */
                   8555: /*   double *popeffectif,*popcount; */
                   8556: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8557: /*   /\* double ***mobaverage; *\/ */
                   8558: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8559: 
1.227     brouard  8560: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8561: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8562: /*   agelim=AGESUP; */
                   8563: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8564:   
1.227     brouard  8565: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8566:   
                   8567:   
1.227     brouard  8568: /*   strcpy(filerespop,"POP_");  */
                   8569: /*   strcat(filerespop,fileresu); */
                   8570: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8571: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8572: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8573: /*   } */
                   8574: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8575: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8576: 
1.227     brouard  8577: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8578: 
1.227     brouard  8579: /*   /\* if (mobilav!=0) { *\/ */
                   8580: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8581: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8582: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8583: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8584: /*   /\*   } *\/ */
                   8585: /*   /\* } *\/ */
1.126     brouard  8586: 
1.227     brouard  8587: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8588: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8589:   
1.227     brouard  8590: /*   agelim=AGESUP; */
1.126     brouard  8591:   
1.227     brouard  8592: /*   hstepm=1; */
                   8593: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8594:        
1.227     brouard  8595: /*   if (popforecast==1) { */
                   8596: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8597: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8598: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8599: /*     }  */
                   8600: /*     popage=ivector(0,AGESUP); */
                   8601: /*     popeffectif=vector(0,AGESUP); */
                   8602: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8603:     
1.227     brouard  8604: /*     i=1;    */
                   8605: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8606:     
1.227     brouard  8607: /*     imx=i; */
                   8608: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8609: /*   } */
1.218     brouard  8610:   
1.227     brouard  8611: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8612: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8613: /*       k=k+1; */
                   8614: /*       fprintf(ficrespop,"\n#******"); */
                   8615: /*       for(j=1;j<=cptcoveff;j++) { */
                   8616: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8617: /*       } */
                   8618: /*       fprintf(ficrespop,"******\n"); */
                   8619: /*       fprintf(ficrespop,"# Age"); */
                   8620: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8621: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8622:       
1.227     brouard  8623: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8624: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8625:        
1.227     brouard  8626: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8627: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8628: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8629:          
1.227     brouard  8630: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8631: /*       oldm=oldms;savm=savms; */
                   8632: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8633:          
1.227     brouard  8634: /*       for (h=0; h<=nhstepm; h++){ */
                   8635: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8636: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8637: /*         }  */
                   8638: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8639: /*           kk1=0.;kk2=0; */
                   8640: /*           for(i=1; i<=nlstate;i++) {               */
                   8641: /*             if (mobilav==1)  */
                   8642: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8643: /*             else { */
                   8644: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8645: /*             } */
                   8646: /*           } */
                   8647: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8648: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8649: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8650: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8651: /*           } */
                   8652: /*         } */
                   8653: /*         for(i=1; i<=nlstate;i++){ */
                   8654: /*           kk1=0.; */
                   8655: /*           for(j=1; j<=nlstate;j++){ */
                   8656: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8657: /*           } */
                   8658: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8659: /*         } */
1.218     brouard  8660:            
1.227     brouard  8661: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8662: /*           for(j=1; j<=nlstate;j++)  */
                   8663: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8664: /*       } */
                   8665: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8666: /*     } */
                   8667: /*       } */
1.218     brouard  8668:       
1.227     brouard  8669: /*       /\******\/ */
1.218     brouard  8670:       
1.227     brouard  8671: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8672: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8673: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8674: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8675: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8676:          
1.227     brouard  8677: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8678: /*       oldm=oldms;savm=savms; */
                   8679: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8680: /*       for (h=0; h<=nhstepm; h++){ */
                   8681: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8682: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8683: /*         }  */
                   8684: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8685: /*           kk1=0.;kk2=0; */
                   8686: /*           for(i=1; i<=nlstate;i++) {               */
                   8687: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8688: /*           } */
                   8689: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8690: /*         } */
                   8691: /*       } */
                   8692: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8693: /*     } */
                   8694: /*       } */
                   8695: /*     }  */
                   8696: /*   } */
1.218     brouard  8697:   
1.227     brouard  8698: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8699:   
1.227     brouard  8700: /*   if (popforecast==1) { */
                   8701: /*     free_ivector(popage,0,AGESUP); */
                   8702: /*     free_vector(popeffectif,0,AGESUP); */
                   8703: /*     free_vector(popcount,0,AGESUP); */
                   8704: /*   } */
                   8705: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8706: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8707: /*   fclose(ficrespop); */
                   8708: /* } /\* End of popforecast *\/ */
1.218     brouard  8709:  
1.126     brouard  8710: int fileappend(FILE *fichier, char *optionfich)
                   8711: {
                   8712:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8713:     printf("Problem with file: %s\n", optionfich);
                   8714:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8715:     return (0);
                   8716:   }
                   8717:   fflush(fichier);
                   8718:   return (1);
                   8719: }
                   8720: 
                   8721: 
                   8722: /**************** function prwizard **********************/
                   8723: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8724: {
                   8725: 
                   8726:   /* Wizard to print covariance matrix template */
                   8727: 
1.164     brouard  8728:   char ca[32], cb[32];
                   8729:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8730:   int numlinepar;
                   8731: 
                   8732:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8733:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8734:   for(i=1; i <=nlstate; i++){
                   8735:     jj=0;
                   8736:     for(j=1; j <=nlstate+ndeath; j++){
                   8737:       if(j==i) continue;
                   8738:       jj++;
                   8739:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8740:       printf("%1d%1d",i,j);
                   8741:       fprintf(ficparo,"%1d%1d",i,j);
                   8742:       for(k=1; k<=ncovmodel;k++){
                   8743:        /*        printf(" %lf",param[i][j][k]); */
                   8744:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8745:        printf(" 0.");
                   8746:        fprintf(ficparo," 0.");
                   8747:       }
                   8748:       printf("\n");
                   8749:       fprintf(ficparo,"\n");
                   8750:     }
                   8751:   }
                   8752:   printf("# Scales (for hessian or gradient estimation)\n");
                   8753:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8754:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8755:   for(i=1; i <=nlstate; i++){
                   8756:     jj=0;
                   8757:     for(j=1; j <=nlstate+ndeath; j++){
                   8758:       if(j==i) continue;
                   8759:       jj++;
                   8760:       fprintf(ficparo,"%1d%1d",i,j);
                   8761:       printf("%1d%1d",i,j);
                   8762:       fflush(stdout);
                   8763:       for(k=1; k<=ncovmodel;k++){
                   8764:        /*      printf(" %le",delti3[i][j][k]); */
                   8765:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8766:        printf(" 0.");
                   8767:        fprintf(ficparo," 0.");
                   8768:       }
                   8769:       numlinepar++;
                   8770:       printf("\n");
                   8771:       fprintf(ficparo,"\n");
                   8772:     }
                   8773:   }
                   8774:   printf("# Covariance matrix\n");
                   8775: /* # 121 Var(a12)\n\ */
                   8776: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8777: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8778: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8779: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8780: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8781: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8782: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8783:   fflush(stdout);
                   8784:   fprintf(ficparo,"# Covariance matrix\n");
                   8785:   /* # 121 Var(a12)\n\ */
                   8786:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8787:   /* #   ...\n\ */
                   8788:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8789:   
                   8790:   for(itimes=1;itimes<=2;itimes++){
                   8791:     jj=0;
                   8792:     for(i=1; i <=nlstate; i++){
                   8793:       for(j=1; j <=nlstate+ndeath; j++){
                   8794:        if(j==i) continue;
                   8795:        for(k=1; k<=ncovmodel;k++){
                   8796:          jj++;
                   8797:          ca[0]= k+'a'-1;ca[1]='\0';
                   8798:          if(itimes==1){
                   8799:            printf("#%1d%1d%d",i,j,k);
                   8800:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8801:          }else{
                   8802:            printf("%1d%1d%d",i,j,k);
                   8803:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8804:            /*  printf(" %.5le",matcov[i][j]); */
                   8805:          }
                   8806:          ll=0;
                   8807:          for(li=1;li <=nlstate; li++){
                   8808:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8809:              if(lj==li) continue;
                   8810:              for(lk=1;lk<=ncovmodel;lk++){
                   8811:                ll++;
                   8812:                if(ll<=jj){
                   8813:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8814:                  if(ll<jj){
                   8815:                    if(itimes==1){
                   8816:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8817:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8818:                    }else{
                   8819:                      printf(" 0.");
                   8820:                      fprintf(ficparo," 0.");
                   8821:                    }
                   8822:                  }else{
                   8823:                    if(itimes==1){
                   8824:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8825:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8826:                    }else{
                   8827:                      printf(" 0.");
                   8828:                      fprintf(ficparo," 0.");
                   8829:                    }
                   8830:                  }
                   8831:                }
                   8832:              } /* end lk */
                   8833:            } /* end lj */
                   8834:          } /* end li */
                   8835:          printf("\n");
                   8836:          fprintf(ficparo,"\n");
                   8837:          numlinepar++;
                   8838:        } /* end k*/
                   8839:       } /*end j */
                   8840:     } /* end i */
                   8841:   } /* end itimes */
                   8842: 
                   8843: } /* end of prwizard */
                   8844: /******************* Gompertz Likelihood ******************************/
                   8845: double gompertz(double x[])
                   8846: { 
                   8847:   double A,B,L=0.0,sump=0.,num=0.;
                   8848:   int i,n=0; /* n is the size of the sample */
                   8849: 
1.220     brouard  8850:   for (i=1;i<=imx ; i++) {
1.126     brouard  8851:     sump=sump+weight[i];
                   8852:     /*    sump=sump+1;*/
                   8853:     num=num+1;
                   8854:   }
                   8855:  
                   8856:  
                   8857:   /* for (i=0; i<=imx; i++) 
                   8858:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8859: 
                   8860:   for (i=1;i<=imx ; i++)
                   8861:     {
                   8862:       if (cens[i] == 1 && wav[i]>1)
                   8863:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8864:       
                   8865:       if (cens[i] == 0 && wav[i]>1)
                   8866:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8867:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8868:       
                   8869:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8870:       if (wav[i] > 1 ) { /* ??? */
                   8871:        L=L+A*weight[i];
                   8872:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8873:       }
                   8874:     }
                   8875: 
                   8876:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8877:  
                   8878:   return -2*L*num/sump;
                   8879: }
                   8880: 
1.136     brouard  8881: #ifdef GSL
                   8882: /******************* Gompertz_f Likelihood ******************************/
                   8883: double gompertz_f(const gsl_vector *v, void *params)
                   8884: { 
                   8885:   double A,B,LL=0.0,sump=0.,num=0.;
                   8886:   double *x= (double *) v->data;
                   8887:   int i,n=0; /* n is the size of the sample */
                   8888: 
                   8889:   for (i=0;i<=imx-1 ; i++) {
                   8890:     sump=sump+weight[i];
                   8891:     /*    sump=sump+1;*/
                   8892:     num=num+1;
                   8893:   }
                   8894:  
                   8895:  
                   8896:   /* for (i=0; i<=imx; i++) 
                   8897:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8898:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8899:   for (i=1;i<=imx ; i++)
                   8900:     {
                   8901:       if (cens[i] == 1 && wav[i]>1)
                   8902:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8903:       
                   8904:       if (cens[i] == 0 && wav[i]>1)
                   8905:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8906:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8907:       
                   8908:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8909:       if (wav[i] > 1 ) { /* ??? */
                   8910:        LL=LL+A*weight[i];
                   8911:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8912:       }
                   8913:     }
                   8914: 
                   8915:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8916:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8917:  
                   8918:   return -2*LL*num/sump;
                   8919: }
                   8920: #endif
                   8921: 
1.126     brouard  8922: /******************* Printing html file ***********/
1.201     brouard  8923: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8924:                  int lastpass, int stepm, int weightopt, char model[],\
                   8925:                  int imx,  double p[],double **matcov,double agemortsup){
                   8926:   int i,k;
                   8927: 
                   8928:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8929:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8930:   for (i=1;i<=2;i++) 
                   8931:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8932:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8933:   fprintf(fichtm,"</ul>");
                   8934: 
                   8935: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8936: 
                   8937:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8938: 
                   8939:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8940:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8941: 
                   8942:  
                   8943:   fflush(fichtm);
                   8944: }
                   8945: 
                   8946: /******************* Gnuplot file **************/
1.201     brouard  8947: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8948: 
                   8949:   char dirfileres[132],optfileres[132];
1.164     brouard  8950: 
1.126     brouard  8951:   int ng;
                   8952: 
                   8953: 
                   8954:   /*#ifdef windows */
                   8955:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8956:     /*#endif */
                   8957: 
                   8958: 
                   8959:   strcpy(dirfileres,optionfilefiname);
                   8960:   strcpy(optfileres,"vpl");
1.199     brouard  8961:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8962:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8963:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8964:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8965:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8966: 
                   8967: } 
                   8968: 
1.136     brouard  8969: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8970: {
1.126     brouard  8971: 
1.136     brouard  8972:   /*-------- data file ----------*/
                   8973:   FILE *fic;
                   8974:   char dummy[]="                         ";
1.240     brouard  8975:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8976:   int lstra;
1.136     brouard  8977:   int linei, month, year,iout;
                   8978:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8979:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8980:   char *stratrunc;
1.223     brouard  8981: 
1.240     brouard  8982:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8983:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8984: 
1.240     brouard  8985:   for(v=1; v <=ncovcol;v++){
                   8986:     DummyV[v]=0;
                   8987:     FixedV[v]=0;
                   8988:   }
                   8989:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8990:     DummyV[v]=1;
                   8991:     FixedV[v]=0;
                   8992:   }
                   8993:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8994:     DummyV[v]=0;
                   8995:     FixedV[v]=1;
                   8996:   }
                   8997:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8998:     DummyV[v]=1;
                   8999:     FixedV[v]=1;
                   9000:   }
                   9001:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9002:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9003:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9004:   }
1.126     brouard  9005: 
1.136     brouard  9006:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9007:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9008:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9009:   }
1.126     brouard  9010: 
1.136     brouard  9011:   i=1;
                   9012:   linei=0;
                   9013:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9014:     linei=linei+1;
                   9015:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9016:       if(line[j] == '\t')
                   9017:        line[j] = ' ';
                   9018:     }
                   9019:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9020:       ;
                   9021:     };
                   9022:     line[j+1]=0;  /* Trims blanks at end of line */
                   9023:     if(line[0]=='#'){
                   9024:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9025:       printf("Comment line\n%s\n",line);
                   9026:       continue;
                   9027:     }
                   9028:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9029:     strcpy(line, linetmp);
1.223     brouard  9030:     
                   9031:     /* Loops on waves */
                   9032:     for (j=maxwav;j>=1;j--){
                   9033:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9034:        cutv(stra, strb, line, ' '); 
                   9035:        if(strb[0]=='.') { /* Missing value */
                   9036:          lval=-1;
                   9037:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9038:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9039:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9040:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9041:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9042:            return 1;
                   9043:          }
                   9044:        }else{
                   9045:          errno=0;
                   9046:          /* what_kind_of_number(strb); */
                   9047:          dval=strtod(strb,&endptr); 
                   9048:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9049:          /* if(strb != endptr && *endptr == '\0') */
                   9050:          /*    dval=dlval; */
                   9051:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9052:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9053:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9054:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9055:            return 1;
                   9056:          }
                   9057:          cotqvar[j][iv][i]=dval; 
                   9058:          cotvar[j][ntv+iv][i]=dval; 
                   9059:        }
                   9060:        strcpy(line,stra);
1.223     brouard  9061:       }/* end loop ntqv */
1.225     brouard  9062:       
1.223     brouard  9063:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9064:        cutv(stra, strb, line, ' '); 
                   9065:        if(strb[0]=='.') { /* Missing value */
                   9066:          lval=-1;
                   9067:        }else{
                   9068:          errno=0;
                   9069:          lval=strtol(strb,&endptr,10); 
                   9070:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9071:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9072:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9073:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9074:            return 1;
                   9075:          }
                   9076:        }
                   9077:        if(lval <-1 || lval >1){
                   9078:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9079:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9080:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9081:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9082:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9083:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9084:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9085:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9086:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9087:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9088:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9089:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9090:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9091:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9092:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9093:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9094:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9095:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9096:          return 1;
                   9097:        }
                   9098:        cotvar[j][iv][i]=(double)(lval);
                   9099:        strcpy(line,stra);
1.223     brouard  9100:       }/* end loop ntv */
1.225     brouard  9101:       
1.223     brouard  9102:       /* Statuses  at wave */
1.137     brouard  9103:       cutv(stra, strb, line, ' '); 
1.223     brouard  9104:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9105:        lval=-1;
1.136     brouard  9106:       }else{
1.238     brouard  9107:        errno=0;
                   9108:        lval=strtol(strb,&endptr,10); 
                   9109:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9110:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9111:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9112:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9113:          return 1;
                   9114:        }
1.136     brouard  9115:       }
1.225     brouard  9116:       
1.136     brouard  9117:       s[j][i]=lval;
1.225     brouard  9118:       
1.223     brouard  9119:       /* Date of Interview */
1.136     brouard  9120:       strcpy(line,stra);
                   9121:       cutv(stra, strb,line,' ');
1.169     brouard  9122:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9123:       }
1.169     brouard  9124:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9125:        month=99;
                   9126:        year=9999;
1.136     brouard  9127:       }else{
1.225     brouard  9128:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9129:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9130:        return 1;
1.136     brouard  9131:       }
                   9132:       anint[j][i]= (double) year; 
                   9133:       mint[j][i]= (double)month; 
                   9134:       strcpy(line,stra);
1.223     brouard  9135:     } /* End loop on waves */
1.225     brouard  9136:     
1.223     brouard  9137:     /* Date of death */
1.136     brouard  9138:     cutv(stra, strb,line,' '); 
1.169     brouard  9139:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9140:     }
1.169     brouard  9141:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9142:       month=99;
                   9143:       year=9999;
                   9144:     }else{
1.141     brouard  9145:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9146:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9147:       return 1;
1.136     brouard  9148:     }
                   9149:     andc[i]=(double) year; 
                   9150:     moisdc[i]=(double) month; 
                   9151:     strcpy(line,stra);
                   9152:     
1.223     brouard  9153:     /* Date of birth */
1.136     brouard  9154:     cutv(stra, strb,line,' '); 
1.169     brouard  9155:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9156:     }
1.169     brouard  9157:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9158:       month=99;
                   9159:       year=9999;
                   9160:     }else{
1.141     brouard  9161:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9162:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9163:       return 1;
1.136     brouard  9164:     }
                   9165:     if (year==9999) {
1.141     brouard  9166:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9167:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9168:       return 1;
                   9169:       
1.136     brouard  9170:     }
                   9171:     annais[i]=(double)(year);
                   9172:     moisnais[i]=(double)(month); 
                   9173:     strcpy(line,stra);
1.225     brouard  9174:     
1.223     brouard  9175:     /* Sample weight */
1.136     brouard  9176:     cutv(stra, strb,line,' '); 
                   9177:     errno=0;
                   9178:     dval=strtod(strb,&endptr); 
                   9179:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9180:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9181:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9182:       fflush(ficlog);
                   9183:       return 1;
                   9184:     }
                   9185:     weight[i]=dval; 
                   9186:     strcpy(line,stra);
1.225     brouard  9187:     
1.223     brouard  9188:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9189:       cutv(stra, strb, line, ' '); 
                   9190:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9191:        lval=-1;
1.223     brouard  9192:       }else{
1.225     brouard  9193:        errno=0;
                   9194:        /* what_kind_of_number(strb); */
                   9195:        dval=strtod(strb,&endptr);
                   9196:        /* if(strb != endptr && *endptr == '\0') */
                   9197:        /*   dval=dlval; */
                   9198:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9199:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9200:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9201:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9202:          return 1;
                   9203:        }
                   9204:        coqvar[iv][i]=dval; 
1.226     brouard  9205:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9206:       }
                   9207:       strcpy(line,stra);
                   9208:     }/* end loop nqv */
1.136     brouard  9209:     
1.223     brouard  9210:     /* Covariate values */
1.136     brouard  9211:     for (j=ncovcol;j>=1;j--){
                   9212:       cutv(stra, strb,line,' '); 
1.223     brouard  9213:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9214:        lval=-1;
1.136     brouard  9215:       }else{
1.225     brouard  9216:        errno=0;
                   9217:        lval=strtol(strb,&endptr,10); 
                   9218:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9219:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9220:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9221:          return 1;
                   9222:        }
1.136     brouard  9223:       }
                   9224:       if(lval <-1 || lval >1){
1.225     brouard  9225:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9226:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9227:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9228:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9229:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9230:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9231:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9232:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9233:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9234:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9235:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9236:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9237:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9238:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9239:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9240:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9241:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9242:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9243:        return 1;
1.136     brouard  9244:       }
                   9245:       covar[j][i]=(double)(lval);
                   9246:       strcpy(line,stra);
                   9247:     }  
                   9248:     lstra=strlen(stra);
1.225     brouard  9249:     
1.136     brouard  9250:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9251:       stratrunc = &(stra[lstra-9]);
                   9252:       num[i]=atol(stratrunc);
                   9253:     }
                   9254:     else
                   9255:       num[i]=atol(stra);
                   9256:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9257:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9258:     
                   9259:     i=i+1;
                   9260:   } /* End loop reading  data */
1.225     brouard  9261:   
1.136     brouard  9262:   *imax=i-1; /* Number of individuals */
                   9263:   fclose(fic);
1.225     brouard  9264:   
1.136     brouard  9265:   return (0);
1.164     brouard  9266:   /* endread: */
1.225     brouard  9267:   printf("Exiting readdata: ");
                   9268:   fclose(fic);
                   9269:   return (1);
1.223     brouard  9270: }
1.126     brouard  9271: 
1.234     brouard  9272: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9273:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9274:   while (*p2 == ' ')
1.234     brouard  9275:     p2++; 
                   9276:   /* while ((*p1++ = *p2++) !=0) */
                   9277:   /*   ; */
                   9278:   /* do */
                   9279:   /*   while (*p2 == ' ') */
                   9280:   /*     p2++; */
                   9281:   /* while (*p1++ == *p2++); */
                   9282:   *stri=p2; 
1.145     brouard  9283: }
                   9284: 
1.235     brouard  9285: int decoderesult ( char resultline[], int nres)
1.230     brouard  9286: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9287: {
1.235     brouard  9288:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9289:   char resultsav[MAXLINE];
1.234     brouard  9290:   int resultmodel[MAXLINE];
                   9291:   int modelresult[MAXLINE];
1.230     brouard  9292:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9293: 
1.234     brouard  9294:   removefirstspace(&resultline);
1.233     brouard  9295:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9296: 
                   9297:   if (strstr(resultline,"v") !=0){
                   9298:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9299:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9300:     return 1;
                   9301:   }
                   9302:   trimbb(resultsav, resultline);
                   9303:   if (strlen(resultsav) >1){
                   9304:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9305:   }
1.253     brouard  9306:   if(j == 0){ /* Resultline but no = */
                   9307:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9308:     return (0);
                   9309:   }
                   9310:     
1.234     brouard  9311:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9312:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9313:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9314:   }
                   9315:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9316:     if(nbocc(resultsav,'=') >1){
                   9317:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9318:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9319:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9320:     }else
                   9321:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9322:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9323:     
1.230     brouard  9324:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9325:     Tvarsel[k]=atoi(strc);
                   9326:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9327:     /* cptcovsel++;     */
                   9328:     if (nbocc(stra,'=') >0)
                   9329:       strcpy(resultsav,stra); /* and analyzes it */
                   9330:   }
1.235     brouard  9331:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9332:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9333:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9334:       match=0;
1.236     brouard  9335:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9336:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9337:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9338:          match=1;
                   9339:          break;
                   9340:        }
                   9341:       }
                   9342:       if(match == 0){
                   9343:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9344:       }
                   9345:     }
                   9346:   }
1.235     brouard  9347:   /* Checking for missing or useless values in comparison of current model needs */
                   9348:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9349:     match=0;
1.235     brouard  9350:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9351:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9352:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9353:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9354:          ++match;
                   9355:        }
                   9356:       }
                   9357:     }
                   9358:     if(match == 0){
                   9359:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9360:     }else if(match > 1){
                   9361:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9362:     }
                   9363:   }
1.235     brouard  9364:       
1.234     brouard  9365:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9366:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9367:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9368:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9369:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9370:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9371:   /*    1 0 0 0 */
                   9372:   /*    2 1 0 0 */
                   9373:   /*    3 0 1 0 */ 
                   9374:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9375:   /*    5 0 0 1 */
                   9376:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9377:   /*    7 0 1 1 */
                   9378:   /*    8 1 1 1 */
1.237     brouard  9379:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9380:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9381:   /* V5*age V5 known which value for nres?  */
                   9382:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9383:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9384:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9385:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9386:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9387:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9388:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9389:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9390:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9391:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9392:       k4++;;
                   9393:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9394:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9395:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9396:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9397:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9398:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9399:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9400:       k4q++;;
                   9401:     }
                   9402:   }
1.234     brouard  9403:   
1.235     brouard  9404:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9405:   return (0);
                   9406: }
1.235     brouard  9407: 
1.230     brouard  9408: int decodemodel( char model[], int lastobs)
                   9409:  /**< This routine decodes the model and returns:
1.224     brouard  9410:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9411:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9412:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9413:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9414:        * - cptcovage number of covariates with age*products =2
                   9415:        * - cptcovs number of simple covariates
                   9416:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9417:        *     which is a new column after the 9 (ncovcol) variables. 
                   9418:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9419:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9420:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9421:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9422:        */
1.136     brouard  9423: {
1.238     brouard  9424:   int i, j, k, ks, v;
1.227     brouard  9425:   int  j1, k1, k2, k3, k4;
1.136     brouard  9426:   char modelsav[80];
1.145     brouard  9427:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9428:   char *strpt;
1.136     brouard  9429: 
1.145     brouard  9430:   /*removespace(model);*/
1.136     brouard  9431:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9432:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9433:     if (strstr(model,"AGE") !=0){
1.192     brouard  9434:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9435:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9436:       return 1;
                   9437:     }
1.141     brouard  9438:     if (strstr(model,"v") !=0){
                   9439:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9440:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9441:       return 1;
                   9442:     }
1.187     brouard  9443:     strcpy(modelsav,model); 
                   9444:     if ((strpt=strstr(model,"age*age")) !=0){
                   9445:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9446:       if(strpt != model){
1.234     brouard  9447:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9448:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9449:  corresponding column of parameters.\n",model);
1.234     brouard  9450:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9451:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9452:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9453:        return 1;
1.225     brouard  9454:       }
1.187     brouard  9455:       nagesqr=1;
                   9456:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9457:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9458:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9459:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9460:       else 
1.234     brouard  9461:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9462:     }else
                   9463:       nagesqr=0;
                   9464:     if (strlen(modelsav) >1){
                   9465:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9466:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9467:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9468:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9469:                     * cst, age and age*age 
                   9470:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9471:       /* including age products which are counted in cptcovage.
                   9472:        * but the covariates which are products must be treated 
                   9473:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9474:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9475:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9476:       
                   9477:       
1.187     brouard  9478:       /*   Design
                   9479:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9480:        *  <          ncovcol=8                >
                   9481:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9482:        *   k=  1    2      3       4     5       6      7        8
                   9483:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9484:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9485:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9486:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9487:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9488:        *  Tage[++cptcovage]=k
                   9489:        *       if products, new covar are created after ncovcol with k1
                   9490:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9491:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9492:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9493:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9494:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9495:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9496:        *  <          ncovcol=8                >
                   9497:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9498:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9499:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9500:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9501:        * p Tprod[1]@2={                         6, 5}
                   9502:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9503:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9504:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9505:        *How to reorganize?
                   9506:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9507:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9508:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9509:        * Struct []
                   9510:        */
1.225     brouard  9511:       
1.187     brouard  9512:       /* This loop fills the array Tvar from the string 'model'.*/
                   9513:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9514:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9515:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9516:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9517:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9518:       /*       k=1 Tvar[1]=2 (from V2) */
                   9519:       /*       k=5 Tvar[5] */
                   9520:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9521:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9522:       /*       } */
1.198     brouard  9523:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9524:       /*
                   9525:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9526:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9527:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9528:       }
1.187     brouard  9529:       cptcovage=0;
                   9530:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9531:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9532:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9533:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9534:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9535:        /*scanf("%d",i);*/
                   9536:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9537:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9538:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9539:            /* covar is not filled and then is empty */
                   9540:            cptcovprod--;
                   9541:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9542:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9543:            Typevar[k]=1;  /* 1 for age product */
                   9544:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9545:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9546:            /*printf("stre=%s ", stre);*/
                   9547:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9548:            cptcovprod--;
                   9549:            cutl(stre,strb,strc,'V');
                   9550:            Tvar[k]=atoi(stre);
                   9551:            Typevar[k]=1;  /* 1 for age product */
                   9552:            cptcovage++;
                   9553:            Tage[cptcovage]=k;
                   9554:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9555:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9556:            cptcovn++;
                   9557:            cptcovprodnoage++;k1++;
                   9558:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9559:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9560:                                                because this model-covariate is a construction we invent a new column
                   9561:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9562:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9563:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9564:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9565:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9566:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9567:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9568:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9569:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9570:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9571:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9572:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9573:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9574:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9575:            for (i=1; i<=lastobs;i++){
                   9576:              /* Computes the new covariate which is a product of
                   9577:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9578:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9579:            }
                   9580:          } /* End age is not in the model */
                   9581:        } /* End if model includes a product */
                   9582:        else { /* no more sum */
                   9583:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9584:          /*  scanf("%d",i);*/
                   9585:          cutl(strd,strc,strb,'V');
                   9586:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9587:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9588:          Tvar[k]=atoi(strd);
                   9589:          Typevar[k]=0;  /* 0 for simple covariates */
                   9590:        }
                   9591:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9592:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9593:                                  scanf("%d",i);*/
1.187     brouard  9594:       } /* end of loop + on total covariates */
                   9595:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9596:   } /* end if strlen(model == 0) */
1.136     brouard  9597:   
                   9598:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9599:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9600:   
1.136     brouard  9601:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9602:      printf("cptcovprod=%d ", cptcovprod);
                   9603:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9604:      scanf("%d ",i);*/
                   9605: 
                   9606: 
1.230     brouard  9607: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9608:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9609: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9610:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9611:    k =           1    2   3     4       5       6      7      8        9
                   9612:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9613:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9614:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9615:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9616:          Tmodelind[combination of covar]=k;
1.225     brouard  9617: */  
                   9618: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9619:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9620:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9621:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9622:   printf("Model=%s\n\
                   9623: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9624: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9625: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9626:   fprintf(ficlog,"Model=%s\n\
                   9627: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9628: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9629: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9630:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9631:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9632:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9633:       Fixed[k]= 0;
                   9634:       Dummy[k]= 0;
1.225     brouard  9635:       ncoveff++;
1.232     brouard  9636:       ncovf++;
1.234     brouard  9637:       nsd++;
                   9638:       modell[k].maintype= FTYPE;
                   9639:       TvarsD[nsd]=Tvar[k];
                   9640:       TvarsDind[nsd]=k;
                   9641:       TvarF[ncovf]=Tvar[k];
                   9642:       TvarFind[ncovf]=k;
                   9643:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9644:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9645:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9646:       Fixed[k]= 0;
                   9647:       Dummy[k]= 0;
                   9648:       ncoveff++;
                   9649:       ncovf++;
                   9650:       modell[k].maintype= FTYPE;
                   9651:       TvarF[ncovf]=Tvar[k];
                   9652:       TvarFind[ncovf]=k;
1.230     brouard  9653:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9654:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9655:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9656:       Fixed[k]= 0;
                   9657:       Dummy[k]= 1;
1.230     brouard  9658:       nqfveff++;
1.234     brouard  9659:       modell[k].maintype= FTYPE;
                   9660:       modell[k].subtype= FQ;
                   9661:       nsq++;
                   9662:       TvarsQ[nsq]=Tvar[k];
                   9663:       TvarsQind[nsq]=k;
1.232     brouard  9664:       ncovf++;
1.234     brouard  9665:       TvarF[ncovf]=Tvar[k];
                   9666:       TvarFind[ncovf]=k;
1.231     brouard  9667:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9668:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9669:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9670:       Fixed[k]= 1;
                   9671:       Dummy[k]= 0;
1.225     brouard  9672:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9673:       modell[k].maintype= VTYPE;
                   9674:       modell[k].subtype= VD;
                   9675:       nsd++;
                   9676:       TvarsD[nsd]=Tvar[k];
                   9677:       TvarsDind[nsd]=k;
                   9678:       ncovv++; /* Only simple time varying variables */
                   9679:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9680:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9681:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9682:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9683:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9684:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9685:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9686:       Fixed[k]= 1;
                   9687:       Dummy[k]= 1;
                   9688:       nqtveff++;
                   9689:       modell[k].maintype= VTYPE;
                   9690:       modell[k].subtype= VQ;
                   9691:       ncovv++; /* Only simple time varying variables */
                   9692:       nsq++;
                   9693:       TvarsQ[nsq]=Tvar[k];
                   9694:       TvarsQind[nsq]=k;
                   9695:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9696:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9697:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9698:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9699:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9700:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9701:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9702:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9703:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9704:       ncova++;
                   9705:       TvarA[ncova]=Tvar[k];
                   9706:       TvarAind[ncova]=k;
1.231     brouard  9707:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9708:        Fixed[k]= 2;
                   9709:        Dummy[k]= 2;
                   9710:        modell[k].maintype= ATYPE;
                   9711:        modell[k].subtype= APFD;
                   9712:        /* ncoveff++; */
1.227     brouard  9713:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9714:        Fixed[k]= 2;
                   9715:        Dummy[k]= 3;
                   9716:        modell[k].maintype= ATYPE;
                   9717:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9718:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9719:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9720:        Fixed[k]= 3;
                   9721:        Dummy[k]= 2;
                   9722:        modell[k].maintype= ATYPE;
                   9723:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9724:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9725:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9726:        Fixed[k]= 3;
                   9727:        Dummy[k]= 3;
                   9728:        modell[k].maintype= ATYPE;
                   9729:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9730:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9731:       }
                   9732:     }else if (Typevar[k] == 2) {  /* product without age */
                   9733:       k1=Tposprod[k];
                   9734:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9735:        if(Tvard[k1][2] <=ncovcol){
                   9736:          Fixed[k]= 1;
                   9737:          Dummy[k]= 0;
                   9738:          modell[k].maintype= FTYPE;
                   9739:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9740:          ncovf++; /* Fixed variables without age */
                   9741:          TvarF[ncovf]=Tvar[k];
                   9742:          TvarFind[ncovf]=k;
                   9743:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9744:          Fixed[k]= 0;  /* or 2 ?*/
                   9745:          Dummy[k]= 1;
                   9746:          modell[k].maintype= FTYPE;
                   9747:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9748:          ncovf++; /* Varying variables without age */
                   9749:          TvarF[ncovf]=Tvar[k];
                   9750:          TvarFind[ncovf]=k;
                   9751:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9752:          Fixed[k]= 1;
                   9753:          Dummy[k]= 0;
                   9754:          modell[k].maintype= VTYPE;
                   9755:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9756:          ncovv++; /* Varying variables without age */
                   9757:          TvarV[ncovv]=Tvar[k];
                   9758:          TvarVind[ncovv]=k;
                   9759:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9760:          Fixed[k]= 1;
                   9761:          Dummy[k]= 1;
                   9762:          modell[k].maintype= VTYPE;
                   9763:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9764:          ncovv++; /* Varying variables without age */
                   9765:          TvarV[ncovv]=Tvar[k];
                   9766:          TvarVind[ncovv]=k;
                   9767:        }
1.227     brouard  9768:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9769:        if(Tvard[k1][2] <=ncovcol){
                   9770:          Fixed[k]= 0;  /* or 2 ?*/
                   9771:          Dummy[k]= 1;
                   9772:          modell[k].maintype= FTYPE;
                   9773:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9774:          ncovf++; /* Fixed variables without age */
                   9775:          TvarF[ncovf]=Tvar[k];
                   9776:          TvarFind[ncovf]=k;
                   9777:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9778:          Fixed[k]= 1;
                   9779:          Dummy[k]= 1;
                   9780:          modell[k].maintype= VTYPE;
                   9781:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9782:          ncovv++; /* Varying variables without age */
                   9783:          TvarV[ncovv]=Tvar[k];
                   9784:          TvarVind[ncovv]=k;
                   9785:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9786:          Fixed[k]= 1;
                   9787:          Dummy[k]= 1;
                   9788:          modell[k].maintype= VTYPE;
                   9789:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9790:          ncovv++; /* Varying variables without age */
                   9791:          TvarV[ncovv]=Tvar[k];
                   9792:          TvarVind[ncovv]=k;
                   9793:          ncovv++; /* Varying variables without age */
                   9794:          TvarV[ncovv]=Tvar[k];
                   9795:          TvarVind[ncovv]=k;
                   9796:        }
1.227     brouard  9797:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9798:        if(Tvard[k1][2] <=ncovcol){
                   9799:          Fixed[k]= 1;
                   9800:          Dummy[k]= 1;
                   9801:          modell[k].maintype= VTYPE;
                   9802:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9803:          ncovv++; /* Varying variables without age */
                   9804:          TvarV[ncovv]=Tvar[k];
                   9805:          TvarVind[ncovv]=k;
                   9806:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9807:          Fixed[k]= 1;
                   9808:          Dummy[k]= 1;
                   9809:          modell[k].maintype= VTYPE;
                   9810:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9811:          ncovv++; /* Varying variables without age */
                   9812:          TvarV[ncovv]=Tvar[k];
                   9813:          TvarVind[ncovv]=k;
                   9814:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9815:          Fixed[k]= 1;
                   9816:          Dummy[k]= 0;
                   9817:          modell[k].maintype= VTYPE;
                   9818:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9819:          ncovv++; /* Varying variables without age */
                   9820:          TvarV[ncovv]=Tvar[k];
                   9821:          TvarVind[ncovv]=k;
                   9822:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9823:          Fixed[k]= 1;
                   9824:          Dummy[k]= 1;
                   9825:          modell[k].maintype= VTYPE;
                   9826:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9827:          ncovv++; /* Varying variables without age */
                   9828:          TvarV[ncovv]=Tvar[k];
                   9829:          TvarVind[ncovv]=k;
                   9830:        }
1.227     brouard  9831:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9832:        if(Tvard[k1][2] <=ncovcol){
                   9833:          Fixed[k]= 1;
                   9834:          Dummy[k]= 1;
                   9835:          modell[k].maintype= VTYPE;
                   9836:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9837:          ncovv++; /* Varying variables without age */
                   9838:          TvarV[ncovv]=Tvar[k];
                   9839:          TvarVind[ncovv]=k;
                   9840:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9841:          Fixed[k]= 1;
                   9842:          Dummy[k]= 1;
                   9843:          modell[k].maintype= VTYPE;
                   9844:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9845:          ncovv++; /* Varying variables without age */
                   9846:          TvarV[ncovv]=Tvar[k];
                   9847:          TvarVind[ncovv]=k;
                   9848:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9849:          Fixed[k]= 1;
                   9850:          Dummy[k]= 1;
                   9851:          modell[k].maintype= VTYPE;
                   9852:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9853:          ncovv++; /* Varying variables without age */
                   9854:          TvarV[ncovv]=Tvar[k];
                   9855:          TvarVind[ncovv]=k;
                   9856:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9857:          Fixed[k]= 1;
                   9858:          Dummy[k]= 1;
                   9859:          modell[k].maintype= VTYPE;
                   9860:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9861:          ncovv++; /* Varying variables without age */
                   9862:          TvarV[ncovv]=Tvar[k];
                   9863:          TvarVind[ncovv]=k;
                   9864:        }
1.227     brouard  9865:       }else{
1.240     brouard  9866:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9867:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9868:       } /*end k1*/
1.225     brouard  9869:     }else{
1.226     brouard  9870:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9871:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9872:     }
1.227     brouard  9873:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9874:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9875:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9876:   }
                   9877:   /* Searching for doublons in the model */
                   9878:   for(k1=1; k1<= cptcovt;k1++){
                   9879:     for(k2=1; k2 <k1;k2++){
                   9880:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9881:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9882:          if(Tvar[k1]==Tvar[k2]){
                   9883:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9884:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9885:            return(1);
                   9886:          }
                   9887:        }else if (Typevar[k1] ==2){
                   9888:          k3=Tposprod[k1];
                   9889:          k4=Tposprod[k2];
                   9890:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9891:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9892:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9893:            return(1);
                   9894:          }
                   9895:        }
1.227     brouard  9896:       }
                   9897:     }
1.225     brouard  9898:   }
                   9899:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9900:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9901:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9902:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9903:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9904:   /*endread:*/
1.225     brouard  9905:   printf("Exiting decodemodel: ");
                   9906:   return (1);
1.136     brouard  9907: }
                   9908: 
1.169     brouard  9909: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9910: {/* Check ages at death */
1.136     brouard  9911:   int i, m;
1.218     brouard  9912:   int firstone=0;
                   9913:   
1.136     brouard  9914:   for (i=1; i<=imx; i++) {
                   9915:     for(m=2; (m<= maxwav); m++) {
                   9916:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9917:        anint[m][i]=9999;
1.216     brouard  9918:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9919:          s[m][i]=-1;
1.136     brouard  9920:       }
                   9921:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9922:        *nberr = *nberr + 1;
1.218     brouard  9923:        if(firstone == 0){
                   9924:          firstone=1;
1.260     brouard  9925:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9926:        }
1.262     brouard  9927:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9928:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9929:       }
                   9930:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9931:        (*nberr)++;
1.259     brouard  9932:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9933:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9934:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9935:       }
                   9936:     }
                   9937:   }
                   9938: 
                   9939:   for (i=1; i<=imx; i++)  {
                   9940:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9941:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9942:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9943:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9944:          if(agedc[i]>0){
                   9945:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9946:              agev[m][i]=agedc[i];
1.214     brouard  9947:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9948:            }else {
1.136     brouard  9949:              if ((int)andc[i]!=9999){
                   9950:                nbwarn++;
                   9951:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9952:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9953:                agev[m][i]=-1;
                   9954:              }
                   9955:            }
1.169     brouard  9956:          } /* agedc > 0 */
1.214     brouard  9957:        } /* end if */
1.136     brouard  9958:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9959:                                 years but with the precision of a month */
                   9960:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9961:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9962:            agev[m][i]=1;
                   9963:          else if(agev[m][i] < *agemin){ 
                   9964:            *agemin=agev[m][i];
                   9965:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9966:          }
                   9967:          else if(agev[m][i] >*agemax){
                   9968:            *agemax=agev[m][i];
1.156     brouard  9969:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9970:          }
                   9971:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9972:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9973:        } /* en if 9*/
1.136     brouard  9974:        else { /* =9 */
1.214     brouard  9975:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9976:          agev[m][i]=1;
                   9977:          s[m][i]=-1;
                   9978:        }
                   9979:       }
1.214     brouard  9980:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9981:        agev[m][i]=1;
1.214     brouard  9982:       else{
                   9983:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9984:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9985:        agev[m][i]=0;
                   9986:       }
                   9987:     } /* End for lastpass */
                   9988:   }
1.136     brouard  9989:     
                   9990:   for (i=1; i<=imx; i++)  {
                   9991:     for(m=firstpass; (m<=lastpass); m++){
                   9992:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9993:        (*nberr)++;
1.136     brouard  9994:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9995:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9996:        return 1;
                   9997:       }
                   9998:     }
                   9999:   }
                   10000: 
                   10001:   /*for (i=1; i<=imx; i++){
                   10002:   for (m=firstpass; (m<lastpass); m++){
                   10003:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10004: }
                   10005: 
                   10006: }*/
                   10007: 
                   10008: 
1.139     brouard  10009:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10010:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10011: 
                   10012:   return (0);
1.164     brouard  10013:  /* endread:*/
1.136     brouard  10014:     printf("Exiting calandcheckages: ");
                   10015:     return (1);
                   10016: }
                   10017: 
1.172     brouard  10018: #if defined(_MSC_VER)
                   10019: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10020: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10021: //#include "stdafx.h"
                   10022: //#include <stdio.h>
                   10023: //#include <tchar.h>
                   10024: //#include <windows.h>
                   10025: //#include <iostream>
                   10026: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10027: 
                   10028: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10029: 
                   10030: BOOL IsWow64()
                   10031: {
                   10032:        BOOL bIsWow64 = FALSE;
                   10033: 
                   10034:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10035:        //  (HANDLE, PBOOL);
                   10036: 
                   10037:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10038: 
                   10039:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10040:        const char funcName[] = "IsWow64Process";
                   10041:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10042:                GetProcAddress(module, funcName);
                   10043: 
                   10044:        if (NULL != fnIsWow64Process)
                   10045:        {
                   10046:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10047:                        &bIsWow64))
                   10048:                        //throw std::exception("Unknown error");
                   10049:                        printf("Unknown error\n");
                   10050:        }
                   10051:        return bIsWow64 != FALSE;
                   10052: }
                   10053: #endif
1.177     brouard  10054: 
1.191     brouard  10055: void syscompilerinfo(int logged)
1.167     brouard  10056:  {
                   10057:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10058:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10059:    /* /GS /W3 /Gy
                   10060:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10061:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10062:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10063:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10064:    */ 
                   10065:    /* 64 bits */
1.185     brouard  10066:    /*
                   10067:      /GS /W3 /Gy
                   10068:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10069:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10070:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10071:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10072:    /* Optimization are useless and O3 is slower than O2 */
                   10073:    /*
                   10074:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10075:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10076:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10077:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10078:    */
1.186     brouard  10079:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10080:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10081:       /PDB:"visual studio
                   10082:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10083:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10084:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10085:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10086:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10087:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10088:       uiAccess='false'"
                   10089:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10090:       /NOLOGO /TLBID:1
                   10091:    */
1.177     brouard  10092: #if defined __INTEL_COMPILER
1.178     brouard  10093: #if defined(__GNUC__)
                   10094:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10095: #endif
1.177     brouard  10096: #elif defined(__GNUC__) 
1.179     brouard  10097: #ifndef  __APPLE__
1.174     brouard  10098: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10099: #endif
1.177     brouard  10100:    struct utsname sysInfo;
1.178     brouard  10101:    int cross = CROSS;
                   10102:    if (cross){
                   10103:           printf("Cross-");
1.191     brouard  10104:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10105:    }
1.174     brouard  10106: #endif
                   10107: 
1.171     brouard  10108: #include <stdint.h>
1.178     brouard  10109: 
1.191     brouard  10110:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10111: #if defined(__clang__)
1.191     brouard  10112:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10113: #endif
                   10114: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10115:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10116: #endif
                   10117: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10118:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10119: #endif
                   10120: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10121:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10122: #endif
                   10123: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10124:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10125: #endif
                   10126: #if defined(_MSC_VER)
1.191     brouard  10127:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10128: #endif
                   10129: #if defined(__PGI)
1.191     brouard  10130:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10131: #endif
                   10132: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10133:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10134: #endif
1.191     brouard  10135:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10136:    
1.167     brouard  10137: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10138: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10139:     // Windows (x64 and x86)
1.191     brouard  10140:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10141: #elif __unix__ // all unices, not all compilers
                   10142:     // Unix
1.191     brouard  10143:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10144: #elif __linux__
                   10145:     // linux
1.191     brouard  10146:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10147: #elif __APPLE__
1.174     brouard  10148:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10149:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10150: #endif
                   10151: 
                   10152: /*  __MINGW32__          */
                   10153: /*  __CYGWIN__  */
                   10154: /* __MINGW64__  */
                   10155: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10156: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10157: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10158: /* _WIN64  // Defined for applications for Win64. */
                   10159: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10160: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10161: 
1.167     brouard  10162: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10163:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10164: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10165:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10166: #else
1.191     brouard  10167:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10168: #endif
                   10169: 
1.169     brouard  10170: #if defined(__GNUC__)
                   10171: # if defined(__GNUC_PATCHLEVEL__)
                   10172: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10173:                             + __GNUC_MINOR__ * 100 \
                   10174:                             + __GNUC_PATCHLEVEL__)
                   10175: # else
                   10176: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10177:                             + __GNUC_MINOR__ * 100)
                   10178: # endif
1.174     brouard  10179:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10180:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10181: 
                   10182:    if (uname(&sysInfo) != -1) {
                   10183:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10184:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10185:    }
                   10186:    else
                   10187:       perror("uname() error");
1.179     brouard  10188:    //#ifndef __INTEL_COMPILER 
                   10189: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10190:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10191:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10192: #endif
1.169     brouard  10193: #endif
1.172     brouard  10194: 
                   10195:    //   void main()
                   10196:    //   {
1.169     brouard  10197: #if defined(_MSC_VER)
1.174     brouard  10198:    if (IsWow64()){
1.191     brouard  10199:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10200:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10201:    }
                   10202:    else{
1.191     brouard  10203:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10204:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10205:    }
1.172     brouard  10206:    //     printf("\nPress Enter to continue...");
                   10207:    //     getchar();
                   10208:    //   }
                   10209: 
1.169     brouard  10210: #endif
                   10211:    
1.167     brouard  10212: 
1.219     brouard  10213: }
1.136     brouard  10214: 
1.219     brouard  10215: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10216:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10217:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10218:   /* double ftolpl = 1.e-10; */
1.180     brouard  10219:   double age, agebase, agelim;
1.203     brouard  10220:   double tot;
1.180     brouard  10221: 
1.202     brouard  10222:   strcpy(filerespl,"PL_");
                   10223:   strcat(filerespl,fileresu);
                   10224:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10225:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10226:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10227:   }
1.227     brouard  10228:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10229:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10230:   pstamp(ficrespl);
1.203     brouard  10231:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10232:   fprintf(ficrespl,"#Age ");
                   10233:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10234:   fprintf(ficrespl,"\n");
1.180     brouard  10235:   
1.219     brouard  10236:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10237: 
1.219     brouard  10238:   agebase=ageminpar;
                   10239:   agelim=agemaxpar;
1.180     brouard  10240: 
1.227     brouard  10241:   /* i1=pow(2,ncoveff); */
1.234     brouard  10242:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10243:   if (cptcovn < 1){i1=1;}
1.180     brouard  10244: 
1.238     brouard  10245:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10246:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10247:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10248:        continue;
1.235     brouard  10249: 
1.238     brouard  10250:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10251:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10252:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10253:       /* k=k+1; */
                   10254:       /* to clean */
                   10255:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10256:       fprintf(ficrespl,"#******");
                   10257:       printf("#******");
                   10258:       fprintf(ficlog,"#******");
                   10259:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10260:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10261:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10262:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10263:       }
                   10264:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10265:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10266:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10267:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10268:       }
                   10269:       fprintf(ficrespl,"******\n");
                   10270:       printf("******\n");
                   10271:       fprintf(ficlog,"******\n");
                   10272:       if(invalidvarcomb[k]){
                   10273:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10274:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10275:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10276:        continue;
                   10277:       }
1.219     brouard  10278: 
1.238     brouard  10279:       fprintf(ficrespl,"#Age ");
                   10280:       for(j=1;j<=cptcoveff;j++) {
                   10281:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10282:       }
                   10283:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10284:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10285:     
1.238     brouard  10286:       for (age=agebase; age<=agelim; age++){
                   10287:        /* for (age=agebase; age<=agebase; age++){ */
                   10288:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10289:        fprintf(ficrespl,"%.0f ",age );
                   10290:        for(j=1;j<=cptcoveff;j++)
                   10291:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10292:        tot=0.;
                   10293:        for(i=1; i<=nlstate;i++){
                   10294:          tot +=  prlim[i][i];
                   10295:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10296:        }
                   10297:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10298:       } /* Age */
                   10299:       /* was end of cptcod */
                   10300:     } /* cptcov */
                   10301:   } /* nres */
1.219     brouard  10302:   return 0;
1.180     brouard  10303: }
                   10304: 
1.218     brouard  10305: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10306:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10307:        
                   10308:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10309:    * at any age between ageminpar and agemaxpar
                   10310:         */
1.235     brouard  10311:   int i, j, k, i1, nres=0 ;
1.217     brouard  10312:   /* double ftolpl = 1.e-10; */
                   10313:   double age, agebase, agelim;
                   10314:   double tot;
1.218     brouard  10315:   /* double ***mobaverage; */
                   10316:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10317: 
                   10318:   strcpy(fileresplb,"PLB_");
                   10319:   strcat(fileresplb,fileresu);
                   10320:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10321:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10322:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10323:   }
                   10324:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10325:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10326:   pstamp(ficresplb);
                   10327:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10328:   fprintf(ficresplb,"#Age ");
                   10329:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10330:   fprintf(ficresplb,"\n");
                   10331:   
1.218     brouard  10332:   
                   10333:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10334:   
                   10335:   agebase=ageminpar;
                   10336:   agelim=agemaxpar;
                   10337:   
                   10338:   
1.227     brouard  10339:   i1=pow(2,cptcoveff);
1.218     brouard  10340:   if (cptcovn < 1){i1=1;}
1.227     brouard  10341:   
1.238     brouard  10342:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10343:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10344:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10345:        continue;
                   10346:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10347:       fprintf(ficresplb,"#******");
                   10348:       printf("#******");
                   10349:       fprintf(ficlog,"#******");
                   10350:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10351:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10352:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10353:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10354:       }
                   10355:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10356:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10357:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10358:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10359:       }
                   10360:       fprintf(ficresplb,"******\n");
                   10361:       printf("******\n");
                   10362:       fprintf(ficlog,"******\n");
                   10363:       if(invalidvarcomb[k]){
                   10364:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10365:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10366:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10367:        continue;
                   10368:       }
1.218     brouard  10369:     
1.238     brouard  10370:       fprintf(ficresplb,"#Age ");
                   10371:       for(j=1;j<=cptcoveff;j++) {
                   10372:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10373:       }
                   10374:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10375:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10376:     
                   10377:     
1.238     brouard  10378:       for (age=agebase; age<=agelim; age++){
                   10379:        /* for (age=agebase; age<=agebase; age++){ */
                   10380:        if(mobilavproj > 0){
                   10381:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10382:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10383:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10384:        }else if (mobilavproj == 0){
                   10385:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10386:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10387:          exit(1);
                   10388:        }else{
                   10389:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10390:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10391:          /* printf("TOTOT\n"); */
                   10392:           /* exit(1); */
1.238     brouard  10393:        }
                   10394:        fprintf(ficresplb,"%.0f ",age );
                   10395:        for(j=1;j<=cptcoveff;j++)
                   10396:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10397:        tot=0.;
                   10398:        for(i=1; i<=nlstate;i++){
                   10399:          tot +=  bprlim[i][i];
                   10400:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10401:        }
                   10402:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10403:       } /* Age */
                   10404:       /* was end of cptcod */
1.255     brouard  10405:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10406:     } /* end of any combination */
                   10407:   } /* end of nres */  
1.218     brouard  10408:   /* hBijx(p, bage, fage); */
                   10409:   /* fclose(ficrespijb); */
                   10410:   
                   10411:   return 0;
1.217     brouard  10412: }
1.218     brouard  10413:  
1.180     brouard  10414: int hPijx(double *p, int bage, int fage){
                   10415:     /*------------- h Pij x at various ages ------------*/
                   10416: 
                   10417:   int stepsize;
                   10418:   int agelim;
                   10419:   int hstepm;
                   10420:   int nhstepm;
1.235     brouard  10421:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10422: 
                   10423:   double agedeb;
                   10424:   double ***p3mat;
                   10425: 
1.201     brouard  10426:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10427:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10428:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10429:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10430:     }
                   10431:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10432:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10433:   
                   10434:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10435:     /*if (stepm<=24) stepsize=2;*/
                   10436: 
                   10437:     agelim=AGESUP;
                   10438:     hstepm=stepsize*YEARM; /* Every year of age */
                   10439:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10440:                
1.180     brouard  10441:     /* hstepm=1;   aff par mois*/
                   10442:     pstamp(ficrespij);
                   10443:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10444:     i1= pow(2,cptcoveff);
1.218     brouard  10445:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10446:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10447:                /*      k=k+1;  */
1.235     brouard  10448:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10449:     for(k=1; k<=i1;k++){
1.253     brouard  10450:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10451:        continue;
1.183     brouard  10452:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10453:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10454:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10455:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10456:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10457:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10458:       }
1.183     brouard  10459:       fprintf(ficrespij,"******\n");
                   10460:       
                   10461:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10462:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10463:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10464:        
                   10465:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10466:        
1.183     brouard  10467:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10468:        oldm=oldms;savm=savms;
1.235     brouard  10469:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10470:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10471:        for(i=1; i<=nlstate;i++)
                   10472:          for(j=1; j<=nlstate+ndeath;j++)
                   10473:            fprintf(ficrespij," %1d-%1d",i,j);
                   10474:        fprintf(ficrespij,"\n");
                   10475:        for (h=0; h<=nhstepm; h++){
                   10476:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10477:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10478:          for(i=1; i<=nlstate;i++)
                   10479:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10480:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10481:          fprintf(ficrespij,"\n");
                   10482:        }
1.183     brouard  10483:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10484:        fprintf(ficrespij,"\n");
                   10485:       }
1.180     brouard  10486:       /*}*/
                   10487:     }
1.218     brouard  10488:     return 0;
1.180     brouard  10489: }
1.218     brouard  10490:  
                   10491:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10492:     /*------------- h Bij x at various ages ------------*/
                   10493: 
                   10494:   int stepsize;
1.218     brouard  10495:   /* int agelim; */
                   10496:        int ageminl;
1.217     brouard  10497:   int hstepm;
                   10498:   int nhstepm;
1.238     brouard  10499:   int h, i, i1, j, k, nres;
1.218     brouard  10500:        
1.217     brouard  10501:   double agedeb;
                   10502:   double ***p3mat;
1.218     brouard  10503:        
                   10504:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10505:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10506:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10507:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10508:   }
                   10509:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10510:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10511:   
                   10512:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10513:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10514:   
1.218     brouard  10515:   /* agelim=AGESUP; */
                   10516:   ageminl=30;
                   10517:   hstepm=stepsize*YEARM; /* Every year of age */
                   10518:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10519:   
                   10520:   /* hstepm=1;   aff par mois*/
                   10521:   pstamp(ficrespijb);
1.255     brouard  10522:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10523:   i1= pow(2,cptcoveff);
1.218     brouard  10524:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10525:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10526:   /*   k=k+1;  */
1.238     brouard  10527:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10528:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10529:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10530:        continue;
                   10531:       fprintf(ficrespijb,"\n#****** ");
                   10532:       for(j=1;j<=cptcoveff;j++)
                   10533:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10534:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10535:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10536:       }
                   10537:       fprintf(ficrespijb,"******\n");
1.264     brouard  10538:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10539:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10540:        continue;
                   10541:       }
                   10542:       
                   10543:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10544:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10545:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10546:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10547:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10548:        
                   10549:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10550:        
1.266     brouard  10551:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10552:        /* and memory limitations if stepm is small */
                   10553: 
1.238     brouard  10554:        /* oldm=oldms;savm=savms; */
                   10555:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10556:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10557:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10558:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10559:        for(i=1; i<=nlstate;i++)
                   10560:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10561:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10562:        fprintf(ficrespijb,"\n");
1.238     brouard  10563:        for (h=0; h<=nhstepm; h++){
                   10564:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10565:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10566:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10567:          for(i=1; i<=nlstate;i++)
                   10568:            for(j=1; j<=nlstate+ndeath;j++)
                   10569:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10570:          fprintf(ficrespijb,"\n");
                   10571:        }
                   10572:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10573:        fprintf(ficrespijb,"\n");
                   10574:       } /* end age deb */
                   10575:     } /* end combination */
                   10576:   } /* end nres */
1.218     brouard  10577:   return 0;
                   10578:  } /*  hBijx */
1.217     brouard  10579: 
1.180     brouard  10580: 
1.136     brouard  10581: /***********************************************/
                   10582: /**************** Main Program *****************/
                   10583: /***********************************************/
                   10584: 
                   10585: int main(int argc, char *argv[])
                   10586: {
                   10587: #ifdef GSL
                   10588:   const gsl_multimin_fminimizer_type *T;
                   10589:   size_t iteri = 0, it;
                   10590:   int rval = GSL_CONTINUE;
                   10591:   int status = GSL_SUCCESS;
                   10592:   double ssval;
                   10593: #endif
                   10594:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10595:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10596:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10597:   int jj, ll, li, lj, lk;
1.136     brouard  10598:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10599:   int num_filled;
1.136     brouard  10600:   int itimes;
                   10601:   int NDIM=2;
                   10602:   int vpopbased=0;
1.235     brouard  10603:   int nres=0;
1.258     brouard  10604:   int endishere=0;
1.136     brouard  10605: 
1.274     brouard  10606:   int ncurrv=0; /* Temporary variable */
                   10607:   
1.164     brouard  10608:   char ca[32], cb[32];
1.136     brouard  10609:   /*  FILE *fichtm; *//* Html File */
                   10610:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10611:   struct stat info;
1.191     brouard  10612:   double agedeb=0.;
1.194     brouard  10613: 
                   10614:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10615:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10616: 
1.165     brouard  10617:   double fret;
1.191     brouard  10618:   double dum=0.; /* Dummy variable */
1.136     brouard  10619:   double ***p3mat;
1.218     brouard  10620:   /* double ***mobaverage; */
1.164     brouard  10621: 
                   10622:   char line[MAXLINE];
1.197     brouard  10623:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10624: 
1.234     brouard  10625:   char  modeltemp[MAXLINE];
1.230     brouard  10626:   char resultline[MAXLINE];
                   10627:   
1.136     brouard  10628:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10629:   char *tok, *val; /* pathtot */
1.136     brouard  10630:   int firstobs=1, lastobs=10;
1.195     brouard  10631:   int c,  h , cpt, c2;
1.191     brouard  10632:   int jl=0;
                   10633:   int i1, j1, jk, stepsize=0;
1.194     brouard  10634:   int count=0;
                   10635: 
1.164     brouard  10636:   int *tab; 
1.136     brouard  10637:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10638:   int backcast=0;
1.136     brouard  10639:   int mobilav=0,popforecast=0;
1.191     brouard  10640:   int hstepm=0, nhstepm=0;
1.136     brouard  10641:   int agemortsup;
                   10642:   float  sumlpop=0.;
                   10643:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10644:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10645: 
1.191     brouard  10646:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10647:   double ftolpl=FTOL;
                   10648:   double **prlim;
1.217     brouard  10649:   double **bprlim;
1.136     brouard  10650:   double ***param; /* Matrix of parameters */
1.251     brouard  10651:   double ***paramstart; /* Matrix of starting parameter values */
                   10652:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10653:   double **matcov; /* Matrix of covariance */
1.203     brouard  10654:   double **hess; /* Hessian matrix */
1.136     brouard  10655:   double ***delti3; /* Scale */
                   10656:   double *delti; /* Scale */
                   10657:   double ***eij, ***vareij;
                   10658:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10659: 
1.136     brouard  10660:   double *epj, vepp;
1.164     brouard  10661: 
1.273     brouard  10662:   double dateprev1, dateprev2;
                   10663:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10664:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10665: 
1.136     brouard  10666:   double **ximort;
1.145     brouard  10667:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10668:   int *dcwave;
                   10669: 
1.164     brouard  10670:   char z[1]="c";
1.136     brouard  10671: 
                   10672:   /*char  *strt;*/
                   10673:   char strtend[80];
1.126     brouard  10674: 
1.164     brouard  10675: 
1.126     brouard  10676: /*   setlocale (LC_ALL, ""); */
                   10677: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10678: /*   textdomain (PACKAGE); */
                   10679: /*   setlocale (LC_CTYPE, ""); */
                   10680: /*   setlocale (LC_MESSAGES, ""); */
                   10681: 
                   10682:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10683:   rstart_time = time(NULL);  
                   10684:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10685:   start_time = *localtime(&rstart_time);
1.126     brouard  10686:   curr_time=start_time;
1.157     brouard  10687:   /*tml = *localtime(&start_time.tm_sec);*/
                   10688:   /* strcpy(strstart,asctime(&tml)); */
                   10689:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10690: 
                   10691: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10692: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10693: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10694: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10695: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10696: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10697: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10698: /*   strt=asctime(&tmg); */
                   10699: /*   printf("Time(after) =%s",strstart);  */
                   10700: /*  (void) time (&time_value);
                   10701: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10702: *  tm = *localtime(&time_value);
                   10703: *  strstart=asctime(&tm);
                   10704: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10705: */
                   10706: 
                   10707:   nberr=0; /* Number of errors and warnings */
                   10708:   nbwarn=0;
1.184     brouard  10709: #ifdef WIN32
                   10710:   _getcwd(pathcd, size);
                   10711: #else
1.126     brouard  10712:   getcwd(pathcd, size);
1.184     brouard  10713: #endif
1.191     brouard  10714:   syscompilerinfo(0);
1.196     brouard  10715:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10716:   if(argc <=1){
                   10717:     printf("\nEnter the parameter file name: ");
1.205     brouard  10718:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10719:       printf("ERROR Empty parameter file name\n");
                   10720:       goto end;
                   10721:     }
1.126     brouard  10722:     i=strlen(pathr);
                   10723:     if(pathr[i-1]=='\n')
                   10724:       pathr[i-1]='\0';
1.156     brouard  10725:     i=strlen(pathr);
1.205     brouard  10726:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10727:       pathr[i-1]='\0';
1.205     brouard  10728:     }
                   10729:     i=strlen(pathr);
                   10730:     if( i==0 ){
                   10731:       printf("ERROR Empty parameter file name\n");
                   10732:       goto end;
                   10733:     }
                   10734:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10735:       printf("Pathr |%s|\n",pathr);
                   10736:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10737:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10738:       strcpy (pathtot, val);
                   10739:       if(pathr[0] == '\0') break; /* Dirty */
                   10740:     }
                   10741:   }
                   10742:   else{
                   10743:     strcpy(pathtot,argv[1]);
                   10744:   }
                   10745:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10746:   /*cygwin_split_path(pathtot,path,optionfile);
                   10747:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10748:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10749: 
                   10750:   /* Split argv[0], imach program to get pathimach */
                   10751:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10752:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10753:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10754:  /*   strcpy(pathimach,argv[0]); */
                   10755:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10756:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10757:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10758: #ifdef WIN32
                   10759:   _chdir(path); /* Can be a relative path */
                   10760:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10761: #else
1.126     brouard  10762:   chdir(path); /* Can be a relative path */
1.184     brouard  10763:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10764: #endif
                   10765:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10766:   strcpy(command,"mkdir ");
                   10767:   strcat(command,optionfilefiname);
                   10768:   if((outcmd=system(command)) != 0){
1.169     brouard  10769:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10770:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10771:     /* fclose(ficlog); */
                   10772: /*     exit(1); */
                   10773:   }
                   10774: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10775: /*     perror("mkdir"); */
                   10776: /*   } */
                   10777: 
                   10778:   /*-------- arguments in the command line --------*/
                   10779: 
1.186     brouard  10780:   /* Main Log file */
1.126     brouard  10781:   strcat(filelog, optionfilefiname);
                   10782:   strcat(filelog,".log");    /* */
                   10783:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10784:     printf("Problem with logfile %s\n",filelog);
                   10785:     goto end;
                   10786:   }
                   10787:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10788:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10789:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10790:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10791:  path=%s \n\
                   10792:  optionfile=%s\n\
                   10793:  optionfilext=%s\n\
1.156     brouard  10794:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10795: 
1.197     brouard  10796:   syscompilerinfo(1);
1.167     brouard  10797: 
1.126     brouard  10798:   printf("Local time (at start):%s",strstart);
                   10799:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10800:   fflush(ficlog);
                   10801: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10802: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10803: 
                   10804:   /* */
                   10805:   strcpy(fileres,"r");
                   10806:   strcat(fileres, optionfilefiname);
1.201     brouard  10807:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10808:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10809:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10810: 
1.186     brouard  10811:   /* Main ---------arguments file --------*/
1.126     brouard  10812: 
                   10813:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10814:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10815:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10816:     fflush(ficlog);
1.149     brouard  10817:     /* goto end; */
                   10818:     exit(70); 
1.126     brouard  10819:   }
                   10820: 
                   10821: 
                   10822: 
                   10823:   strcpy(filereso,"o");
1.201     brouard  10824:   strcat(filereso,fileresu);
1.126     brouard  10825:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10826:     printf("Problem with Output resultfile: %s\n", filereso);
                   10827:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10828:     fflush(ficlog);
                   10829:     goto end;
                   10830:   }
                   10831: 
                   10832:   /* Reads comments: lines beginning with '#' */
                   10833:   numlinepar=0;
1.197     brouard  10834: 
                   10835:     /* First parameter line */
                   10836:   while(fgets(line, MAXLINE, ficpar)) {
                   10837:     /* If line starts with a # it is a comment */
                   10838:     if (line[0] == '#') {
                   10839:       numlinepar++;
                   10840:       fputs(line,stdout);
                   10841:       fputs(line,ficparo);
                   10842:       fputs(line,ficlog);
                   10843:       continue;
                   10844:     }else
                   10845:       break;
                   10846:   }
                   10847:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10848:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10849:     if (num_filled != 5) {
                   10850:       printf("Should be 5 parameters\n");
                   10851:     }
1.126     brouard  10852:     numlinepar++;
1.197     brouard  10853:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10854:   }
                   10855:   /* Second parameter line */
                   10856:   while(fgets(line, MAXLINE, ficpar)) {
                   10857:     /* If line starts with a # it is a comment */
                   10858:     if (line[0] == '#') {
                   10859:       numlinepar++;
                   10860:       fputs(line,stdout);
                   10861:       fputs(line,ficparo);
                   10862:       fputs(line,ficlog);
                   10863:       continue;
                   10864:     }else
                   10865:       break;
                   10866:   }
1.223     brouard  10867:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10868:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10869:     if (num_filled != 11) {
                   10870:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10871:       printf("but line=%s\n",line);
1.197     brouard  10872:     }
1.223     brouard  10873:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10874:   }
1.203     brouard  10875:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10876:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10877:   /* Third parameter line */
                   10878:   while(fgets(line, MAXLINE, ficpar)) {
                   10879:     /* If line starts with a # it is a comment */
                   10880:     if (line[0] == '#') {
                   10881:       numlinepar++;
                   10882:       fputs(line,stdout);
                   10883:       fputs(line,ficparo);
                   10884:       fputs(line,ficlog);
                   10885:       continue;
                   10886:     }else
                   10887:       break;
                   10888:   }
1.201     brouard  10889:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10890:     if (num_filled == 0){
                   10891:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10892:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10893:       model[0]='\0';
                   10894:       goto end;
                   10895:     } else if (num_filled != 1){
1.197     brouard  10896:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10897:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10898:       model[0]='\0';
                   10899:       goto end;
                   10900:     }
                   10901:     else{
                   10902:       if (model[0]=='+'){
                   10903:        for(i=1; i<=strlen(model);i++)
                   10904:          modeltemp[i-1]=model[i];
1.201     brouard  10905:        strcpy(model,modeltemp); 
1.197     brouard  10906:       }
                   10907:     }
1.199     brouard  10908:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10909:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10910:   }
                   10911:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10912:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10913:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10914:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10915:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10916:   fflush(ficlog);
1.190     brouard  10917:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10918:   if(model[0]=='#'){
1.187     brouard  10919:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10920:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10921:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10922:     if(mle != -1){
                   10923:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10924:       exit(1);
                   10925:     }
                   10926:   }
1.126     brouard  10927:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10928:     ungetc(c,ficpar);
                   10929:     fgets(line, MAXLINE, ficpar);
                   10930:     numlinepar++;
1.195     brouard  10931:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10932:       z[0]=line[1];
                   10933:     }
                   10934:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10935:     fputs(line, stdout);
                   10936:     //puts(line);
1.126     brouard  10937:     fputs(line,ficparo);
                   10938:     fputs(line,ficlog);
                   10939:   }
                   10940:   ungetc(c,ficpar);
                   10941: 
                   10942:    
1.145     brouard  10943:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10944:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10945:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10946:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10947:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10948:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10949:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10950:   */
                   10951:   if (strlen(model)>1) 
1.187     brouard  10952:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10953:   else
1.187     brouard  10954:     ncovmodel=2; /* Constant and age */
1.133     brouard  10955:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10956:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10957:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10958:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10959:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10960:     fflush(stdout);
                   10961:     fclose (ficlog);
                   10962:     goto end;
                   10963:   }
1.126     brouard  10964:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10965:   delti=delti3[1][1];
                   10966:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10967:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10968: /* We could also provide initial parameters values giving by simple logistic regression 
                   10969:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10970:       /* for(i=1;i<nlstate;i++){ */
                   10971:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10972:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10973:       /* } */
1.126     brouard  10974:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10975:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10976:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10977:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10978:     fclose (ficparo);
                   10979:     fclose (ficlog);
                   10980:     goto end;
                   10981:     exit(0);
1.220     brouard  10982:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10983:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10984:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10985:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10986:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10987:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10988:     hess=matrix(1,npar,1,npar);
1.220     brouard  10989:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10990:     /* Read guessed parameters */
1.126     brouard  10991:     /* Reads comments: lines beginning with '#' */
                   10992:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10993:       ungetc(c,ficpar);
                   10994:       fgets(line, MAXLINE, ficpar);
                   10995:       numlinepar++;
1.141     brouard  10996:       fputs(line,stdout);
1.126     brouard  10997:       fputs(line,ficparo);
                   10998:       fputs(line,ficlog);
                   10999:     }
                   11000:     ungetc(c,ficpar);
                   11001:     
                   11002:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11003:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11004:     for(i=1; i <=nlstate; i++){
1.234     brouard  11005:       j=0;
1.126     brouard  11006:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11007:        if(jj==i) continue;
                   11008:        j++;
                   11009:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11010:        if ((i1 != i) || (j1 != jj)){
                   11011:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11012: It might be a problem of design; if ncovcol and the model are correct\n \
                   11013: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11014:          exit(1);
                   11015:        }
                   11016:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11017:        if(mle==1)
                   11018:          printf("%1d%1d",i,jj);
                   11019:        fprintf(ficlog,"%1d%1d",i,jj);
                   11020:        for(k=1; k<=ncovmodel;k++){
                   11021:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11022:          if(mle==1){
                   11023:            printf(" %lf",param[i][j][k]);
                   11024:            fprintf(ficlog," %lf",param[i][j][k]);
                   11025:          }
                   11026:          else
                   11027:            fprintf(ficlog," %lf",param[i][j][k]);
                   11028:          fprintf(ficparo," %lf",param[i][j][k]);
                   11029:        }
                   11030:        fscanf(ficpar,"\n");
                   11031:        numlinepar++;
                   11032:        if(mle==1)
                   11033:          printf("\n");
                   11034:        fprintf(ficlog,"\n");
                   11035:        fprintf(ficparo,"\n");
1.126     brouard  11036:       }
                   11037:     }  
                   11038:     fflush(ficlog);
1.234     brouard  11039:     
1.251     brouard  11040:     /* Reads parameters values */
1.126     brouard  11041:     p=param[1][1];
1.251     brouard  11042:     pstart=paramstart[1][1];
1.126     brouard  11043:     
                   11044:     /* Reads comments: lines beginning with '#' */
                   11045:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11046:       ungetc(c,ficpar);
                   11047:       fgets(line, MAXLINE, ficpar);
                   11048:       numlinepar++;
1.141     brouard  11049:       fputs(line,stdout);
1.126     brouard  11050:       fputs(line,ficparo);
                   11051:       fputs(line,ficlog);
                   11052:     }
                   11053:     ungetc(c,ficpar);
                   11054: 
                   11055:     for(i=1; i <=nlstate; i++){
                   11056:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11057:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11058:        if ( (i1-i) * (j1-j) != 0){
                   11059:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11060:          exit(1);
                   11061:        }
                   11062:        printf("%1d%1d",i,j);
                   11063:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11064:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11065:        for(k=1; k<=ncovmodel;k++){
                   11066:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11067:          printf(" %le",delti3[i][j][k]);
                   11068:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11069:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11070:        }
                   11071:        fscanf(ficpar,"\n");
                   11072:        numlinepar++;
                   11073:        printf("\n");
                   11074:        fprintf(ficparo,"\n");
                   11075:        fprintf(ficlog,"\n");
1.126     brouard  11076:       }
                   11077:     }
                   11078:     fflush(ficlog);
1.234     brouard  11079:     
1.145     brouard  11080:     /* Reads covariance matrix */
1.126     brouard  11081:     delti=delti3[1][1];
1.220     brouard  11082:                
                   11083:                
1.126     brouard  11084:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11085:                
1.126     brouard  11086:     /* Reads comments: lines beginning with '#' */
                   11087:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11088:       ungetc(c,ficpar);
                   11089:       fgets(line, MAXLINE, ficpar);
                   11090:       numlinepar++;
1.141     brouard  11091:       fputs(line,stdout);
1.126     brouard  11092:       fputs(line,ficparo);
                   11093:       fputs(line,ficlog);
                   11094:     }
                   11095:     ungetc(c,ficpar);
1.220     brouard  11096:                
1.126     brouard  11097:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11098:     hess=matrix(1,npar,1,npar);
1.131     brouard  11099:     for(i=1; i <=npar; i++)
                   11100:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11101:                
1.194     brouard  11102:     /* Scans npar lines */
1.126     brouard  11103:     for(i=1; i <=npar; i++){
1.226     brouard  11104:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11105:       if(count != 3){
1.226     brouard  11106:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11107: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11108: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11109:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11110: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11111: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11112:        exit(1);
1.220     brouard  11113:       }else{
1.226     brouard  11114:        if(mle==1)
                   11115:          printf("%1d%1d%d",i1,j1,jk);
                   11116:       }
                   11117:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11118:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11119:       for(j=1; j <=i; j++){
1.226     brouard  11120:        fscanf(ficpar," %le",&matcov[i][j]);
                   11121:        if(mle==1){
                   11122:          printf(" %.5le",matcov[i][j]);
                   11123:        }
                   11124:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11125:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11126:       }
                   11127:       fscanf(ficpar,"\n");
                   11128:       numlinepar++;
                   11129:       if(mle==1)
1.220     brouard  11130:                                printf("\n");
1.126     brouard  11131:       fprintf(ficlog,"\n");
                   11132:       fprintf(ficparo,"\n");
                   11133:     }
1.194     brouard  11134:     /* End of read covariance matrix npar lines */
1.126     brouard  11135:     for(i=1; i <=npar; i++)
                   11136:       for(j=i+1;j<=npar;j++)
1.226     brouard  11137:        matcov[i][j]=matcov[j][i];
1.126     brouard  11138:     
                   11139:     if(mle==1)
                   11140:       printf("\n");
                   11141:     fprintf(ficlog,"\n");
                   11142:     
                   11143:     fflush(ficlog);
                   11144:     
                   11145:     /*-------- Rewriting parameter file ----------*/
                   11146:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11147:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11148:     strcat(rfileres,".");    /* */
                   11149:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11150:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11151:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11152:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11153:     }
                   11154:     fprintf(ficres,"#%s\n",version);
                   11155:   }    /* End of mle != -3 */
1.218     brouard  11156:   
1.186     brouard  11157:   /*  Main data
                   11158:    */
1.126     brouard  11159:   n= lastobs;
                   11160:   num=lvector(1,n);
                   11161:   moisnais=vector(1,n);
                   11162:   annais=vector(1,n);
                   11163:   moisdc=vector(1,n);
                   11164:   andc=vector(1,n);
1.220     brouard  11165:   weight=vector(1,n);
1.126     brouard  11166:   agedc=vector(1,n);
                   11167:   cod=ivector(1,n);
1.220     brouard  11168:   for(i=1;i<=n;i++){
1.234     brouard  11169:     num[i]=0;
                   11170:     moisnais[i]=0;
                   11171:     annais[i]=0;
                   11172:     moisdc[i]=0;
                   11173:     andc[i]=0;
                   11174:     agedc[i]=0;
                   11175:     cod[i]=0;
                   11176:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11177:   }
1.126     brouard  11178:   mint=matrix(1,maxwav,1,n);
                   11179:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11180:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11181:   tab=ivector(1,NCOVMAX);
1.144     brouard  11182:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11183:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11184: 
1.136     brouard  11185:   /* Reads data from file datafile */
                   11186:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11187:     goto end;
                   11188: 
                   11189:   /* Calculation of the number of parameters from char model */
1.234     brouard  11190:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11191:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11192:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11193:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11194:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11195:   */
                   11196:   
                   11197:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11198:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11199:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11200:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11201:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11202:   TvarF=ivector(1,NCOVMAX); /*  */
                   11203:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11204:   TvarV=ivector(1,NCOVMAX); /*  */
                   11205:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11206:   TvarA=ivector(1,NCOVMAX); /*  */
                   11207:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11208:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11209:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11210:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11211:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11212:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11213:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11214:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11215:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11216: 
1.230     brouard  11217:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11218:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11219:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11220:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11221:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11222:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11223:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11224:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11225:   */
                   11226:   /* For model-covariate k tells which data-covariate to use but
                   11227:     because this model-covariate is a construction we invent a new column
                   11228:     ncovcol + k1
                   11229:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11230:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11231:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11232:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11233:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11234:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11235:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11236:   */
1.145     brouard  11237:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11238:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11239:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11240:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11241:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11242:                         4 covariates (3 plus signs)
                   11243:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11244:                      */  
1.230     brouard  11245:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11246:                                * individual dummy, fixed or varying:
                   11247:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11248:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11249:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11250:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11251:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11252:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11253:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11254:                                * individual quantitative, fixed or varying:
                   11255:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11256:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11257:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11258: /* Main decodemodel */
                   11259: 
1.187     brouard  11260: 
1.223     brouard  11261:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11262:     goto end;
                   11263: 
1.137     brouard  11264:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11265:     nbwarn++;
                   11266:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11267:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11268:   }
1.136     brouard  11269:     /*  if(mle==1){*/
1.137     brouard  11270:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11271:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11272:   }
                   11273: 
                   11274:     /*-calculation of age at interview from date of interview and age at death -*/
                   11275:   agev=matrix(1,maxwav,1,imx);
                   11276: 
                   11277:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11278:     goto end;
                   11279: 
1.126     brouard  11280: 
1.136     brouard  11281:   agegomp=(int)agemin;
                   11282:   free_vector(moisnais,1,n);
                   11283:   free_vector(annais,1,n);
1.126     brouard  11284:   /* free_matrix(mint,1,maxwav,1,n);
                   11285:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11286:   /* free_vector(moisdc,1,n); */
                   11287:   /* free_vector(andc,1,n); */
1.145     brouard  11288:   /* */
                   11289:   
1.126     brouard  11290:   wav=ivector(1,imx);
1.214     brouard  11291:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11292:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11293:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11294:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11295:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11296:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11297:    
                   11298:   /* Concatenates waves */
1.214     brouard  11299:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11300:      Death is a valid wave (if date is known).
                   11301:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11302:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11303:      and mw[mi+1][i]. dh depends on stepm.
                   11304:   */
                   11305: 
1.126     brouard  11306:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11307:   /* Concatenates waves */
1.145     brouard  11308:  
1.215     brouard  11309:   free_vector(moisdc,1,n);
                   11310:   free_vector(andc,1,n);
                   11311: 
1.126     brouard  11312:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11313:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11314:   ncodemax[1]=1;
1.145     brouard  11315:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11316:   cptcoveff=0;
1.220     brouard  11317:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11318:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11319:   }
                   11320:   
                   11321:   ncovcombmax=pow(2,cptcoveff);
                   11322:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11323:   for(i=1;i<ncovcombmax;i++)
                   11324:     invalidvarcomb[i]=0;
                   11325:   
1.211     brouard  11326:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11327:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11328:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11329:   
1.200     brouard  11330:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11331:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11332:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11333:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11334:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11335:    * (currently 0 or 1) in the data.
                   11336:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11337:    * corresponding modality (h,j).
                   11338:    */
                   11339: 
1.145     brouard  11340:   h=0;
                   11341:   /*if (cptcovn > 0) */
1.126     brouard  11342:   m=pow(2,cptcoveff);
                   11343:  
1.144     brouard  11344:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11345:           * For k=4 covariates, h goes from 1 to m=2**k
                   11346:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11347:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11348:           *     h\k   1     2     3     4
1.143     brouard  11349:           *______________________________  
                   11350:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11351:           *     2     2     1     1     1
                   11352:           *     3 i=2 1     2     1     1
                   11353:           *     4     2     2     1     1
                   11354:           *     5 i=3 1 i=2 1     2     1
                   11355:           *     6     2     1     2     1
                   11356:           *     7 i=4 1     2     2     1
                   11357:           *     8     2     2     2     1
1.197     brouard  11358:           *     9 i=5 1 i=3 1 i=2 1     2
                   11359:           *    10     2     1     1     2
                   11360:           *    11 i=6 1     2     1     2
                   11361:           *    12     2     2     1     2
                   11362:           *    13 i=7 1 i=4 1     2     2    
                   11363:           *    14     2     1     2     2
                   11364:           *    15 i=8 1     2     2     2
                   11365:           *    16     2     2     2     2
1.143     brouard  11366:           */
1.212     brouard  11367:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11368:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11369:      * and the value of each covariate?
                   11370:      * V1=1, V2=1, V3=2, V4=1 ?
                   11371:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11372:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11373:      * In order to get the real value in the data, we use nbcode
                   11374:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11375:      * We are keeping this crazy system in order to be able (in the future?) 
                   11376:      * to have more than 2 values (0 or 1) for a covariate.
                   11377:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11378:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11379:      *              bbbbbbbb
                   11380:      *              76543210     
                   11381:      *   h-1        00000101 (6-1=5)
1.219     brouard  11382:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11383:      *           &
                   11384:      *     1        00000001 (1)
1.219     brouard  11385:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11386:      *          +1= 00000001 =1 
1.211     brouard  11387:      *
                   11388:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11389:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11390:      *    >>k'            11
                   11391:      *          &   00000001
                   11392:      *            = 00000001
                   11393:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11394:      * Reverse h=6 and m=16?
                   11395:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11396:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11397:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11398:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11399:      * V3=decodtabm(14,3,2**4)=2
                   11400:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11401:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11402:      *          &1 000000001
                   11403:      *           = 000000001
                   11404:      *         +1= 000000010 =2
                   11405:      *                  2211
                   11406:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11407:      *                  V3=2
1.220     brouard  11408:                 * codtabm and decodtabm are identical
1.211     brouard  11409:      */
                   11410: 
1.145     brouard  11411: 
                   11412:  free_ivector(Ndum,-1,NCOVMAX);
                   11413: 
                   11414: 
1.126     brouard  11415:     
1.186     brouard  11416:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11417:   strcpy(optionfilegnuplot,optionfilefiname);
                   11418:   if(mle==-3)
1.201     brouard  11419:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11420:   strcat(optionfilegnuplot,".gp");
                   11421: 
                   11422:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11423:     printf("Problem with file %s",optionfilegnuplot);
                   11424:   }
                   11425:   else{
1.204     brouard  11426:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11427:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11428:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11429:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11430:   }
                   11431:   /*  fclose(ficgp);*/
1.186     brouard  11432: 
                   11433: 
                   11434:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11435: 
                   11436:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11437:   if(mle==-3)
1.201     brouard  11438:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11439:   strcat(optionfilehtm,".htm");
                   11440:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11441:     printf("Problem with %s \n",optionfilehtm);
                   11442:     exit(0);
1.126     brouard  11443:   }
                   11444: 
                   11445:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11446:   strcat(optionfilehtmcov,"-cov.htm");
                   11447:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11448:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11449:   }
                   11450:   else{
                   11451:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11452: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11453: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11454:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11455:   }
                   11456: 
1.213     brouard  11457:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11458: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11459: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11460: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11461: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11462: \n\
                   11463: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11464:  <ul><li><h4>Parameter files</h4>\n\
                   11465:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11466:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11467:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11468:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11469:  - Date and time at start: %s</ul>\n",\
                   11470:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11471:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11472:          fileres,fileres,\
                   11473:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11474:   fflush(fichtm);
                   11475: 
                   11476:   strcpy(pathr,path);
                   11477:   strcat(pathr,optionfilefiname);
1.184     brouard  11478: #ifdef WIN32
                   11479:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11480: #else
1.126     brouard  11481:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11482: #endif
                   11483:          
1.126     brouard  11484:   
1.220     brouard  11485:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11486:                 and for any valid combination of covariates
1.126     brouard  11487:      and prints on file fileres'p'. */
1.251     brouard  11488:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11489:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11490: 
                   11491:   fprintf(fichtm,"\n");
1.274     brouard  11492:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%f \n<li>Interval for the elementary matrix (in month): stepm=%d",\
                   11493:          ftol, stepm);
                   11494:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11495:   ncurrv=1;
                   11496:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11497:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11498:   ncurrv=i;
                   11499:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11500:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11501:   ncurrv=i;
                   11502:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11503:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11504:   ncurrv=i;
                   11505:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11506:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11507:           nlstate, ndeath, maxwav, mle, weightopt);
                   11508: 
                   11509:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11510: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11511: 
                   11512:   
                   11513:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11514: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11515: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11516:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11517:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11518:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11519:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11520:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11521:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11522: 
1.126     brouard  11523:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11524:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11525:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11526: 
                   11527:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11528:   /* For mortality only */
1.126     brouard  11529:   if (mle==-3){
1.136     brouard  11530:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11531:     for(i=1;i<=NDIM;i++)
                   11532:       for(j=1;j<=NDIM;j++)
                   11533:        ximort[i][j]=0.;
1.186     brouard  11534:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11535:     cens=ivector(1,n);
                   11536:     ageexmed=vector(1,n);
                   11537:     agecens=vector(1,n);
                   11538:     dcwave=ivector(1,n);
1.223     brouard  11539:                
1.126     brouard  11540:     for (i=1; i<=imx; i++){
                   11541:       dcwave[i]=-1;
                   11542:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11543:        if (s[m][i]>nlstate) {
                   11544:          dcwave[i]=m;
                   11545:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11546:          break;
                   11547:        }
1.126     brouard  11548:     }
1.226     brouard  11549:     
1.126     brouard  11550:     for (i=1; i<=imx; i++) {
                   11551:       if (wav[i]>0){
1.226     brouard  11552:        ageexmed[i]=agev[mw[1][i]][i];
                   11553:        j=wav[i];
                   11554:        agecens[i]=1.; 
                   11555:        
                   11556:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11557:          agecens[i]=agev[mw[j][i]][i];
                   11558:          cens[i]= 1;
                   11559:        }else if (ageexmed[i]< 1) 
                   11560:          cens[i]= -1;
                   11561:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11562:          cens[i]=0 ;
1.126     brouard  11563:       }
                   11564:       else cens[i]=-1;
                   11565:     }
                   11566:     
                   11567:     for (i=1;i<=NDIM;i++) {
                   11568:       for (j=1;j<=NDIM;j++)
1.226     brouard  11569:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11570:     }
                   11571:     
1.145     brouard  11572:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11573:     /*printf("%lf %lf", p[1], p[2]);*/
                   11574:     
                   11575:     
1.136     brouard  11576: #ifdef GSL
                   11577:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11578: #else
1.126     brouard  11579:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11580: #endif
1.201     brouard  11581:     strcpy(filerespow,"POW-MORT_"); 
                   11582:     strcat(filerespow,fileresu);
1.126     brouard  11583:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11584:       printf("Problem with resultfile: %s\n", filerespow);
                   11585:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11586:     }
1.136     brouard  11587: #ifdef GSL
                   11588:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11589: #else
1.126     brouard  11590:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11591: #endif
1.126     brouard  11592:     /*  for (i=1;i<=nlstate;i++)
                   11593:        for(j=1;j<=nlstate+ndeath;j++)
                   11594:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11595:     */
                   11596:     fprintf(ficrespow,"\n");
1.136     brouard  11597: #ifdef GSL
                   11598:     /* gsl starts here */ 
                   11599:     T = gsl_multimin_fminimizer_nmsimplex;
                   11600:     gsl_multimin_fminimizer *sfm = NULL;
                   11601:     gsl_vector *ss, *x;
                   11602:     gsl_multimin_function minex_func;
                   11603: 
                   11604:     /* Initial vertex size vector */
                   11605:     ss = gsl_vector_alloc (NDIM);
                   11606:     
                   11607:     if (ss == NULL){
                   11608:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11609:     }
                   11610:     /* Set all step sizes to 1 */
                   11611:     gsl_vector_set_all (ss, 0.001);
                   11612: 
                   11613:     /* Starting point */
1.126     brouard  11614:     
1.136     brouard  11615:     x = gsl_vector_alloc (NDIM);
                   11616:     
                   11617:     if (x == NULL){
                   11618:       gsl_vector_free(ss);
                   11619:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11620:     }
                   11621:   
                   11622:     /* Initialize method and iterate */
                   11623:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11624:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11625:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11626:     gsl_vector_set(x, 0, p[1]);
                   11627:     gsl_vector_set(x, 1, p[2]);
                   11628: 
                   11629:     minex_func.f = &gompertz_f;
                   11630:     minex_func.n = NDIM;
                   11631:     minex_func.params = (void *)&p; /* ??? */
                   11632:     
                   11633:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11634:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11635:     
                   11636:     printf("Iterations beginning .....\n\n");
                   11637:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11638: 
                   11639:     iteri=0;
                   11640:     while (rval == GSL_CONTINUE){
                   11641:       iteri++;
                   11642:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11643:       
                   11644:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11645:       fflush(0);
                   11646:       
                   11647:       if (status) 
                   11648:         break;
                   11649:       
                   11650:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11651:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11652:       
                   11653:       if (rval == GSL_SUCCESS)
                   11654:         printf ("converged to a local maximum at\n");
                   11655:       
                   11656:       printf("%5d ", iteri);
                   11657:       for (it = 0; it < NDIM; it++){
                   11658:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11659:       }
                   11660:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11661:     }
                   11662:     
                   11663:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11664:     
                   11665:     gsl_vector_free(x); /* initial values */
                   11666:     gsl_vector_free(ss); /* inital step size */
                   11667:     for (it=0; it<NDIM; it++){
                   11668:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11669:       fprintf(ficrespow," %.12lf", p[it]);
                   11670:     }
                   11671:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11672: #endif
                   11673: #ifdef POWELL
                   11674:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11675: #endif  
1.126     brouard  11676:     fclose(ficrespow);
                   11677:     
1.203     brouard  11678:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11679: 
                   11680:     for(i=1; i <=NDIM; i++)
                   11681:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11682:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11683:     
                   11684:     printf("\nCovariance matrix\n ");
1.203     brouard  11685:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11686:     for(i=1; i <=NDIM; i++) {
                   11687:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11688:                                printf("%f ",matcov[i][j]);
                   11689:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11690:       }
1.203     brouard  11691:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11692:     }
                   11693:     
                   11694:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11695:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11696:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11697:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11698:     }
1.126     brouard  11699:     lsurv=vector(1,AGESUP);
                   11700:     lpop=vector(1,AGESUP);
                   11701:     tpop=vector(1,AGESUP);
                   11702:     lsurv[agegomp]=100000;
                   11703:     
                   11704:     for (k=agegomp;k<=AGESUP;k++) {
                   11705:       agemortsup=k;
                   11706:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11707:     }
                   11708:     
                   11709:     for (k=agegomp;k<agemortsup;k++)
                   11710:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11711:     
                   11712:     for (k=agegomp;k<agemortsup;k++){
                   11713:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11714:       sumlpop=sumlpop+lpop[k];
                   11715:     }
                   11716:     
                   11717:     tpop[agegomp]=sumlpop;
                   11718:     for (k=agegomp;k<(agemortsup-3);k++){
                   11719:       /*  tpop[k+1]=2;*/
                   11720:       tpop[k+1]=tpop[k]-lpop[k];
                   11721:     }
                   11722:     
                   11723:     
                   11724:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11725:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11726:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11727:     
                   11728:     
                   11729:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11730:                ageminpar=50;
                   11731:                agemaxpar=100;
1.194     brouard  11732:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11733:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11734: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11735: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11736:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11737: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11738: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11739:     }else{
                   11740:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11741:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11742:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11743:                }
1.201     brouard  11744:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11745:                     stepm, weightopt,\
                   11746:                     model,imx,p,matcov,agemortsup);
                   11747:     
                   11748:     free_vector(lsurv,1,AGESUP);
                   11749:     free_vector(lpop,1,AGESUP);
                   11750:     free_vector(tpop,1,AGESUP);
1.220     brouard  11751:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11752:     free_ivector(cens,1,n);
                   11753:     free_vector(agecens,1,n);
                   11754:     free_ivector(dcwave,1,n);
1.220     brouard  11755: #ifdef GSL
1.136     brouard  11756: #endif
1.186     brouard  11757:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11758:   /* Standard  */
                   11759:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11760:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11761:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11762:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11763:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11764:     for (k=1; k<=npar;k++)
                   11765:       printf(" %d %8.5f",k,p[k]);
                   11766:     printf("\n");
1.205     brouard  11767:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11768:       /* mlikeli uses func not funcone */
1.247     brouard  11769:       /* for(i=1;i<nlstate;i++){ */
                   11770:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11771:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11772:       /* } */
1.205     brouard  11773:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11774:     }
                   11775:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11776:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11777:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11778:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11779:     }
                   11780:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11781:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11782:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11783:     for (k=1; k<=npar;k++)
                   11784:       printf(" %d %8.5f",k,p[k]);
                   11785:     printf("\n");
                   11786:     
                   11787:     /*--------- results files --------------*/
1.224     brouard  11788:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11789:     
                   11790:     
                   11791:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11792:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11793:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11794:     for(i=1,jk=1; i <=nlstate; i++){
                   11795:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11796:        if (k != i) {
                   11797:          printf("%d%d ",i,k);
                   11798:          fprintf(ficlog,"%d%d ",i,k);
                   11799:          fprintf(ficres,"%1d%1d ",i,k);
                   11800:          for(j=1; j <=ncovmodel; j++){
                   11801:            printf("%12.7f ",p[jk]);
                   11802:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11803:            fprintf(ficres,"%12.7f ",p[jk]);
                   11804:            jk++; 
                   11805:          }
                   11806:          printf("\n");
                   11807:          fprintf(ficlog,"\n");
                   11808:          fprintf(ficres,"\n");
                   11809:        }
1.126     brouard  11810:       }
                   11811:     }
1.203     brouard  11812:     if(mle != 0){
                   11813:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11814:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11815:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11816:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11817:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11818:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11819:        for(k=1; k <=(nlstate+ndeath); k++){
                   11820:          if (k != i) {
                   11821:            printf("%d%d ",i,k);
                   11822:            fprintf(ficlog,"%d%d ",i,k);
                   11823:            for(j=1; j <=ncovmodel; j++){
                   11824:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11825:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11826:              jk++; 
                   11827:            }
                   11828:            printf("\n");
                   11829:            fprintf(ficlog,"\n");
                   11830:          }
                   11831:        }
1.193     brouard  11832:       }
1.203     brouard  11833:     } /* end of hesscov and Wald tests */
1.225     brouard  11834:     
1.203     brouard  11835:     /*  */
1.126     brouard  11836:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11837:     printf("# Scales (for hessian or gradient estimation)\n");
                   11838:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11839:     for(i=1,jk=1; i <=nlstate; i++){
                   11840:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11841:        if (j!=i) {
                   11842:          fprintf(ficres,"%1d%1d",i,j);
                   11843:          printf("%1d%1d",i,j);
                   11844:          fprintf(ficlog,"%1d%1d",i,j);
                   11845:          for(k=1; k<=ncovmodel;k++){
                   11846:            printf(" %.5e",delti[jk]);
                   11847:            fprintf(ficlog," %.5e",delti[jk]);
                   11848:            fprintf(ficres," %.5e",delti[jk]);
                   11849:            jk++;
                   11850:          }
                   11851:          printf("\n");
                   11852:          fprintf(ficlog,"\n");
                   11853:          fprintf(ficres,"\n");
                   11854:        }
1.126     brouard  11855:       }
                   11856:     }
                   11857:     
                   11858:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11859:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11860:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11861:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11862:     /* # 121 Var(a12)\n\ */
                   11863:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11864:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11865:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11866:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11867:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11868:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11869:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11870:     
                   11871:     
                   11872:     /* Just to have a covariance matrix which will be more understandable
                   11873:        even is we still don't want to manage dictionary of variables
                   11874:     */
                   11875:     for(itimes=1;itimes<=2;itimes++){
                   11876:       jj=0;
                   11877:       for(i=1; i <=nlstate; i++){
1.225     brouard  11878:        for(j=1; j <=nlstate+ndeath; j++){
                   11879:          if(j==i) continue;
                   11880:          for(k=1; k<=ncovmodel;k++){
                   11881:            jj++;
                   11882:            ca[0]= k+'a'-1;ca[1]='\0';
                   11883:            if(itimes==1){
                   11884:              if(mle>=1)
                   11885:                printf("#%1d%1d%d",i,j,k);
                   11886:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11887:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11888:            }else{
                   11889:              if(mle>=1)
                   11890:                printf("%1d%1d%d",i,j,k);
                   11891:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11892:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11893:            }
                   11894:            ll=0;
                   11895:            for(li=1;li <=nlstate; li++){
                   11896:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11897:                if(lj==li) continue;
                   11898:                for(lk=1;lk<=ncovmodel;lk++){
                   11899:                  ll++;
                   11900:                  if(ll<=jj){
                   11901:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11902:                    if(ll<jj){
                   11903:                      if(itimes==1){
                   11904:                        if(mle>=1)
                   11905:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11906:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11907:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11908:                      }else{
                   11909:                        if(mle>=1)
                   11910:                          printf(" %.5e",matcov[jj][ll]); 
                   11911:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11912:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11913:                      }
                   11914:                    }else{
                   11915:                      if(itimes==1){
                   11916:                        if(mle>=1)
                   11917:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11918:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11919:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11920:                      }else{
                   11921:                        if(mle>=1)
                   11922:                          printf(" %.7e",matcov[jj][ll]); 
                   11923:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11924:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11925:                      }
                   11926:                    }
                   11927:                  }
                   11928:                } /* end lk */
                   11929:              } /* end lj */
                   11930:            } /* end li */
                   11931:            if(mle>=1)
                   11932:              printf("\n");
                   11933:            fprintf(ficlog,"\n");
                   11934:            fprintf(ficres,"\n");
                   11935:            numlinepar++;
                   11936:          } /* end k*/
                   11937:        } /*end j */
1.126     brouard  11938:       } /* end i */
                   11939:     } /* end itimes */
                   11940:     
                   11941:     fflush(ficlog);
                   11942:     fflush(ficres);
1.225     brouard  11943:     while(fgets(line, MAXLINE, ficpar)) {
                   11944:       /* If line starts with a # it is a comment */
                   11945:       if (line[0] == '#') {
                   11946:        numlinepar++;
                   11947:        fputs(line,stdout);
                   11948:        fputs(line,ficparo);
                   11949:        fputs(line,ficlog);
                   11950:        continue;
                   11951:       }else
                   11952:        break;
                   11953:     }
                   11954:     
1.209     brouard  11955:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11956:     /*   ungetc(c,ficpar); */
                   11957:     /*   fgets(line, MAXLINE, ficpar); */
                   11958:     /*   fputs(line,stdout); */
                   11959:     /*   fputs(line,ficparo); */
                   11960:     /* } */
                   11961:     /* ungetc(c,ficpar); */
1.126     brouard  11962:     
                   11963:     estepm=0;
1.209     brouard  11964:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11965:       
                   11966:       if (num_filled != 6) {
                   11967:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11968:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11969:        goto end;
                   11970:       }
                   11971:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11972:     }
                   11973:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11974:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11975:     
1.209     brouard  11976:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11977:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11978:     if (fage <= 2) {
                   11979:       bage = ageminpar;
                   11980:       fage = agemaxpar;
                   11981:     }
                   11982:     
                   11983:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11984:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11985:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11986:                
1.186     brouard  11987:     /* Other stuffs, more or less useful */    
1.254     brouard  11988:     while(fgets(line, MAXLINE, ficpar)) {
                   11989:       /* If line starts with a # it is a comment */
                   11990:       if (line[0] == '#') {
                   11991:        numlinepar++;
                   11992:        fputs(line,stdout);
                   11993:        fputs(line,ficparo);
                   11994:        fputs(line,ficlog);
                   11995:        continue;
                   11996:       }else
                   11997:        break;
                   11998:     }
                   11999: 
                   12000:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12001:       
                   12002:       if (num_filled != 7) {
                   12003:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12004:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12005:        goto end;
                   12006:       }
                   12007:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12008:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12009:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12010:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12011:     }
1.254     brouard  12012: 
                   12013:     while(fgets(line, MAXLINE, ficpar)) {
                   12014:       /* If line starts with a # it is a comment */
                   12015:       if (line[0] == '#') {
                   12016:        numlinepar++;
                   12017:        fputs(line,stdout);
                   12018:        fputs(line,ficparo);
                   12019:        fputs(line,ficlog);
                   12020:        continue;
                   12021:       }else
                   12022:        break;
1.126     brouard  12023:     }
                   12024:     
                   12025:     
                   12026:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12027:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12028:     
1.254     brouard  12029:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12030:       if (num_filled != 1) {
                   12031:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12032:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12033:        goto end;
                   12034:       }
                   12035:       printf("pop_based=%d\n",popbased);
                   12036:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12037:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12038:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12039:     }
                   12040:      
1.258     brouard  12041:     /* Results */
                   12042:     nresult=0;
                   12043:     do{
                   12044:       if(!fgets(line, MAXLINE, ficpar)){
                   12045:        endishere=1;
                   12046:        parameterline=14;
                   12047:       }else if (line[0] == '#') {
                   12048:        /* If line starts with a # it is a comment */
1.254     brouard  12049:        numlinepar++;
                   12050:        fputs(line,stdout);
                   12051:        fputs(line,ficparo);
                   12052:        fputs(line,ficlog);
                   12053:        continue;
1.258     brouard  12054:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12055:        parameterline=11;
                   12056:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12057:        parameterline=12;
                   12058:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12059:        parameterline=13;
                   12060:       else{
                   12061:        parameterline=14;
1.254     brouard  12062:       }
1.258     brouard  12063:       switch (parameterline){ 
                   12064:       case 11:
                   12065:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12066:          if (num_filled != 8) {
                   12067:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12068:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12069:            goto end;
                   12070:          }
                   12071:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12072:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12073:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12074:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12075:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12076:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12077:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12078: 
1.258     brouard  12079:        }
1.254     brouard  12080:        break;
1.258     brouard  12081:       case 12:
                   12082:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12083:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12084:          if (num_filled != 8) {
1.262     brouard  12085:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12086:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12087:            goto end;
                   12088:          }
                   12089:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12090:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12091:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12092:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12093:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12094:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12095:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12096:        }
1.230     brouard  12097:        break;
1.258     brouard  12098:       case 13:
                   12099:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12100:          if (num_filled == 0){
                   12101:            resultline[0]='\0';
                   12102:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12103:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12104:            break;
                   12105:          } else if (num_filled != 1){
                   12106:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12107:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12108:          }
                   12109:          nresult++; /* Sum of resultlines */
                   12110:          printf("Result %d: result=%s\n",nresult, resultline);
                   12111:          if(nresult > MAXRESULTLINES){
                   12112:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12113:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12114:            goto end;
                   12115:          }
                   12116:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12117:          fprintf(ficparo,"result: %s\n",resultline);
                   12118:          fprintf(ficres,"result: %s\n",resultline);
                   12119:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12120:          break;
1.258     brouard  12121:        case 14: 
1.259     brouard  12122:          if(ncovmodel >2 && nresult==0 ){
                   12123:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12124:            goto end;
                   12125:          }
1.259     brouard  12126:          break;
1.258     brouard  12127:        default:
                   12128:          nresult=1;
                   12129:          decoderesult(".",nresult ); /* No covariate */
                   12130:        }
                   12131:       } /* End switch parameterline */
                   12132:     }while(endishere==0); /* End do */
1.126     brouard  12133:     
1.230     brouard  12134:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12135:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12136:     
                   12137:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12138:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12139:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12140: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12141: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12142:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12143: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12144: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12145:     }else{
1.270     brouard  12146:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12147:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12148:     }
                   12149:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12150:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12151:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12152:                
1.225     brouard  12153:     /*------------ free_vector  -------------*/
                   12154:     /*  chdir(path); */
1.220     brouard  12155:                
1.215     brouard  12156:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12157:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12158:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12159:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12160:     free_lvector(num,1,n);
                   12161:     free_vector(agedc,1,n);
                   12162:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12163:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12164:     fclose(ficparo);
                   12165:     fclose(ficres);
1.220     brouard  12166:                
                   12167:                
1.186     brouard  12168:     /* Other results (useful)*/
1.220     brouard  12169:                
                   12170:                
1.126     brouard  12171:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12172:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12173:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12174:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12175:     fclose(ficrespl);
                   12176: 
                   12177:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12178:     /*#include "hpijx.h"*/
                   12179:     hPijx(p, bage, fage);
1.145     brouard  12180:     fclose(ficrespij);
1.227     brouard  12181:     
1.220     brouard  12182:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12183:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12184:     k=1;
1.126     brouard  12185:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12186:     
1.269     brouard  12187:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12188:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12189:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12190:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12191:        for(k=1;k<=ncovcombmax;k++)
                   12192:          probs[i][j][k]=0.;
1.269     brouard  12193:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12194:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12195:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12196:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12197:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12198:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12199:          for(k=1;k<=ncovcombmax;k++)
                   12200:            mobaverages[i][j][k]=0.;
1.219     brouard  12201:       mobaverage=mobaverages;
                   12202:       if (mobilav!=0) {
1.235     brouard  12203:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12204:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12205:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12206:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12207:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12208:        }
1.269     brouard  12209:       } else if (mobilavproj !=0) {
1.235     brouard  12210:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12211:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12212:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12213:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12214:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12215:        }
1.269     brouard  12216:       }else{
                   12217:        printf("Internal error moving average\n");
                   12218:        fflush(stdout);
                   12219:        exit(1);
1.219     brouard  12220:       }
                   12221:     }/* end if moving average */
1.227     brouard  12222:     
1.126     brouard  12223:     /*---------- Forecasting ------------------*/
                   12224:     if(prevfcast==1){
                   12225:       /*    if(stepm ==1){*/
1.269     brouard  12226:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12227:     }
1.269     brouard  12228: 
                   12229:     /* Backcasting */
1.217     brouard  12230:     if(backcast==1){
1.219     brouard  12231:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12232:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12233:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12234: 
                   12235:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12236: 
                   12237:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12238: 
1.219     brouard  12239:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12240:       fclose(ficresplb);
                   12241: 
1.222     brouard  12242:       hBijx(p, bage, fage, mobaverage);
                   12243:       fclose(ficrespijb);
1.219     brouard  12244: 
1.269     brouard  12245:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12246:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12247:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12248: 
                   12249:       
1.269     brouard  12250:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12251:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12252:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12253:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12254:     }    /* end  Backcasting */
1.268     brouard  12255:  
1.186     brouard  12256:  
                   12257:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12258: 
1.215     brouard  12259:     free_ivector(wav,1,imx);
                   12260:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12261:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12262:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12263:                
                   12264:                
1.127     brouard  12265:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12266:                
1.201     brouard  12267:     strcpy(filerese,"E_");
                   12268:     strcat(filerese,fileresu);
1.126     brouard  12269:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12270:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12271:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12272:     }
1.208     brouard  12273:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12274:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12275: 
                   12276:     pstamp(ficreseij);
1.219     brouard  12277:                
1.235     brouard  12278:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12279:     if (cptcovn < 1){i1=1;}
                   12280:     
                   12281:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12282:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12283:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12284:        continue;
1.219     brouard  12285:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12286:       printf("\n#****** ");
1.225     brouard  12287:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12288:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12289:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12290:       }
                   12291:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12292:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12293:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12294:       }
                   12295:       fprintf(ficreseij,"******\n");
1.235     brouard  12296:       printf("******\n");
1.219     brouard  12297:       
                   12298:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12299:       oldm=oldms;savm=savms;
1.235     brouard  12300:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12301:       
1.219     brouard  12302:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12303:     }
                   12304:     fclose(ficreseij);
1.208     brouard  12305:     printf("done evsij\n");fflush(stdout);
                   12306:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12307: 
1.218     brouard  12308:                
1.227     brouard  12309:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12310:                
1.201     brouard  12311:     strcpy(filerest,"T_");
                   12312:     strcat(filerest,fileresu);
1.127     brouard  12313:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12314:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12315:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12316:     }
1.208     brouard  12317:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12318:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12319:     strcpy(fileresstde,"STDE_");
                   12320:     strcat(fileresstde,fileresu);
1.126     brouard  12321:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12322:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12323:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12324:     }
1.227     brouard  12325:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12326:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12327: 
1.201     brouard  12328:     strcpy(filerescve,"CVE_");
                   12329:     strcat(filerescve,fileresu);
1.126     brouard  12330:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12331:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12332:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12333:     }
1.227     brouard  12334:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12335:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12336: 
1.201     brouard  12337:     strcpy(fileresv,"V_");
                   12338:     strcat(fileresv,fileresu);
1.126     brouard  12339:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12340:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12341:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12342:     }
1.227     brouard  12343:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12344:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12345: 
1.235     brouard  12346:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12347:     if (cptcovn < 1){i1=1;}
                   12348:     
                   12349:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12350:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12351:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12352:        continue;
1.242     brouard  12353:       printf("\n#****** Result for:");
                   12354:       fprintf(ficrest,"\n#****** Result for:");
                   12355:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12356:       for(j=1;j<=cptcoveff;j++){ 
                   12357:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12358:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12359:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12360:       }
1.235     brouard  12361:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12362:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12363:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12364:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12365:       }        
1.208     brouard  12366:       fprintf(ficrest,"******\n");
1.227     brouard  12367:       fprintf(ficlog,"******\n");
                   12368:       printf("******\n");
1.208     brouard  12369:       
                   12370:       fprintf(ficresstdeij,"\n#****** ");
                   12371:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12372:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12373:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12374:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12375:       }
1.235     brouard  12376:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12377:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12378:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12379:       }        
1.208     brouard  12380:       fprintf(ficresstdeij,"******\n");
                   12381:       fprintf(ficrescveij,"******\n");
                   12382:       
                   12383:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12384:       /* pstamp(ficresvij); */
1.225     brouard  12385:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12386:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12387:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12388:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12389:       }        
1.208     brouard  12390:       fprintf(ficresvij,"******\n");
                   12391:       
                   12392:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12393:       oldm=oldms;savm=savms;
1.235     brouard  12394:       printf(" cvevsij ");
                   12395:       fprintf(ficlog, " cvevsij ");
                   12396:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12397:       printf(" end cvevsij \n ");
                   12398:       fprintf(ficlog, " end cvevsij \n ");
                   12399:       
                   12400:       /*
                   12401:        */
                   12402:       /* goto endfree; */
                   12403:       
                   12404:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12405:       pstamp(ficrest);
                   12406:       
1.269     brouard  12407:       epj=vector(1,nlstate+1);
1.208     brouard  12408:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12409:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12410:        cptcod= 0; /* To be deleted */
                   12411:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12412:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12413:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12414:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12415:        if(vpopbased==1)
                   12416:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12417:        else
                   12418:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12419:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12420:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12421:        fprintf(ficrest,"\n");
                   12422:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12423:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12424:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12425:        for(age=bage; age <=fage ;age++){
1.235     brouard  12426:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12427:          if (vpopbased==1) {
                   12428:            if(mobilav ==0){
                   12429:              for(i=1; i<=nlstate;i++)
                   12430:                prlim[i][i]=probs[(int)age][i][k];
                   12431:            }else{ /* mobilav */ 
                   12432:              for(i=1; i<=nlstate;i++)
                   12433:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12434:            }
                   12435:          }
1.219     brouard  12436:          
1.227     brouard  12437:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12438:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12439:          /* printf(" age %4.0f ",age); */
                   12440:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12441:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12442:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12443:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12444:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12445:            }
                   12446:            epj[nlstate+1] +=epj[j];
                   12447:          }
                   12448:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12449:          
1.227     brouard  12450:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12451:            for(j=1;j <=nlstate;j++)
                   12452:              vepp += vareij[i][j][(int)age];
                   12453:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12454:          for(j=1;j <=nlstate;j++){
                   12455:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12456:          }
                   12457:          fprintf(ficrest,"\n");
                   12458:        }
1.208     brouard  12459:       } /* End vpopbased */
1.269     brouard  12460:       free_vector(epj,1,nlstate+1);
1.208     brouard  12461:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12462:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12463:       printf("done selection\n");fflush(stdout);
                   12464:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12465:       
1.235     brouard  12466:     } /* End k selection */
1.227     brouard  12467: 
                   12468:     printf("done State-specific expectancies\n");fflush(stdout);
                   12469:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12470: 
1.269     brouard  12471:     /* variance-covariance of period prevalence*/
                   12472:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12473: 
1.227     brouard  12474:     
                   12475:     free_vector(weight,1,n);
                   12476:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12477:     free_imatrix(s,1,maxwav+1,1,n);
                   12478:     free_matrix(anint,1,maxwav,1,n); 
                   12479:     free_matrix(mint,1,maxwav,1,n);
                   12480:     free_ivector(cod,1,n);
                   12481:     free_ivector(tab,1,NCOVMAX);
                   12482:     fclose(ficresstdeij);
                   12483:     fclose(ficrescveij);
                   12484:     fclose(ficresvij);
                   12485:     fclose(ficrest);
                   12486:     fclose(ficpar);
                   12487:     
                   12488:     
1.126     brouard  12489:     /*---------- End : free ----------------*/
1.219     brouard  12490:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12491:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12492:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12493:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12494:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12495:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12496:   /* endfree:*/
                   12497:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12498:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12499:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12500:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12501:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12502:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12503:   free_matrix(covar,0,NCOVMAX,1,n);
                   12504:   free_matrix(matcov,1,npar,1,npar);
                   12505:   free_matrix(hess,1,npar,1,npar);
                   12506:   /*free_vector(delti,1,npar);*/
                   12507:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12508:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12509:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12510:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12511:   
                   12512:   free_ivector(ncodemax,1,NCOVMAX);
                   12513:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12514:   free_ivector(Dummy,-1,NCOVMAX);
                   12515:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12516:   free_ivector(DummyV,1,NCOVMAX);
                   12517:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12518:   free_ivector(Typevar,-1,NCOVMAX);
                   12519:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12520:   free_ivector(TvarsQ,1,NCOVMAX);
                   12521:   free_ivector(TvarsQind,1,NCOVMAX);
                   12522:   free_ivector(TvarsD,1,NCOVMAX);
                   12523:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12524:   free_ivector(TvarFD,1,NCOVMAX);
                   12525:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12526:   free_ivector(TvarF,1,NCOVMAX);
                   12527:   free_ivector(TvarFind,1,NCOVMAX);
                   12528:   free_ivector(TvarV,1,NCOVMAX);
                   12529:   free_ivector(TvarVind,1,NCOVMAX);
                   12530:   free_ivector(TvarA,1,NCOVMAX);
                   12531:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12532:   free_ivector(TvarFQ,1,NCOVMAX);
                   12533:   free_ivector(TvarFQind,1,NCOVMAX);
                   12534:   free_ivector(TvarVD,1,NCOVMAX);
                   12535:   free_ivector(TvarVDind,1,NCOVMAX);
                   12536:   free_ivector(TvarVQ,1,NCOVMAX);
                   12537:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12538:   free_ivector(Tvarsel,1,NCOVMAX);
                   12539:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12540:   free_ivector(Tposprod,1,NCOVMAX);
                   12541:   free_ivector(Tprod,1,NCOVMAX);
                   12542:   free_ivector(Tvaraff,1,NCOVMAX);
                   12543:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12544:   free_ivector(Tage,1,NCOVMAX);
                   12545:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12546:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12547:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12548:   
                   12549:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12550:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12551:   fflush(fichtm);
                   12552:   fflush(ficgp);
                   12553:   
1.227     brouard  12554:   
1.126     brouard  12555:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12556:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12557:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12558:   }else{
                   12559:     printf("End of Imach\n");
                   12560:     fprintf(ficlog,"End of Imach\n");
                   12561:   }
                   12562:   printf("See log file on %s\n",filelog);
                   12563:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12564:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12565:   rend_time = time(NULL);  
                   12566:   end_time = *localtime(&rend_time);
                   12567:   /* tml = *localtime(&end_time.tm_sec); */
                   12568:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12569:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12570:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12571:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12572:   
1.157     brouard  12573:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12574:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12575:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12576:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12577: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12578:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12579:   fclose(fichtm);
                   12580:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12581:   fclose(fichtmcov);
                   12582:   fclose(ficgp);
                   12583:   fclose(ficlog);
                   12584:   /*------ End -----------*/
1.227     brouard  12585:   
                   12586:   
                   12587:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12588: #ifdef WIN32
1.227     brouard  12589:   if (_chdir(pathcd) != 0)
                   12590:     printf("Can't move to directory %s!\n",path);
                   12591:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12592: #else
1.227     brouard  12593:     if(chdir(pathcd) != 0)
                   12594:       printf("Can't move to directory %s!\n", path);
                   12595:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12596: #endif 
1.126     brouard  12597:     printf("Current directory %s!\n",pathcd);
                   12598:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12599:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12600: #ifdef _WIN32
1.126     brouard  12601:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12602: #endif
                   12603:   if(!stat(plotcmd,&info)){
1.158     brouard  12604:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12605:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12606:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12607:     }else
                   12608:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12609: #ifdef __unix
1.126     brouard  12610:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12611:     if(!stat(plotcmd,&info)){
1.158     brouard  12612:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12613:     }else
                   12614:       strcpy(pplotcmd,plotcmd);
                   12615: #endif
                   12616:   }else
                   12617:     strcpy(pplotcmd,plotcmd);
                   12618:   
                   12619:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12620:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12621:   
1.126     brouard  12622:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12623:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12624:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12625:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12626:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12627:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12628:   }
1.158     brouard  12629:   printf(" Successful, please wait...");
1.126     brouard  12630:   while (z[0] != 'q') {
                   12631:     /* chdir(path); */
1.154     brouard  12632:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12633:     scanf("%s",z);
                   12634: /*     if (z[0] == 'c') system("./imach"); */
                   12635:     if (z[0] == 'e') {
1.158     brouard  12636: #ifdef __APPLE__
1.152     brouard  12637:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12638: #elif __linux
                   12639:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12640: #else
1.152     brouard  12641:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12642: #endif
                   12643:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12644:       system(pplotcmd);
1.126     brouard  12645:     }
                   12646:     else if (z[0] == 'g') system(plotcmd);
                   12647:     else if (z[0] == 'q') exit(0);
                   12648:   }
1.227     brouard  12649: end:
1.126     brouard  12650:   while (z[0] != 'q') {
1.195     brouard  12651:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12652:     scanf("%s",z);
                   12653:   }
                   12654: }

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>