Annotation of imach/src/imach.c, revision 1.283

1.283   ! brouard     1: /* $Id: imach.c,v 1.282 2018/02/27 22:50:02 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.283   ! brouard     4:   Revision 1.282  2018/02/27 22:50:02  brouard
        !             5:   *** empty log message ***
        !             6: 
1.282     brouard     7:   Revision 1.281  2018/02/27 19:25:23  brouard
                      8:   Summary: Adding second argument for quitting
                      9: 
1.281     brouard    10:   Revision 1.280  2018/02/21 07:58:13  brouard
                     11:   Summary: 0.99r15
                     12: 
                     13:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     14: 
1.280     brouard    15:   Revision 1.279  2017/07/20 13:35:01  brouard
                     16:   Summary: temporary working
                     17: 
1.279     brouard    18:   Revision 1.278  2017/07/19 14:09:02  brouard
                     19:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     20: 
1.278     brouard    21:   Revision 1.277  2017/07/17 08:53:49  brouard
                     22:   Summary: BOM files can be read now
                     23: 
1.277     brouard    24:   Revision 1.276  2017/06/30 15:48:31  brouard
                     25:   Summary: Graphs improvements
                     26: 
1.276     brouard    27:   Revision 1.275  2017/06/30 13:39:33  brouard
                     28:   Summary: Saito's color
                     29: 
1.275     brouard    30:   Revision 1.274  2017/06/29 09:47:08  brouard
                     31:   Summary: Version 0.99r14
                     32: 
1.274     brouard    33:   Revision 1.273  2017/06/27 11:06:02  brouard
                     34:   Summary: More documentation on projections
                     35: 
1.273     brouard    36:   Revision 1.272  2017/06/27 10:22:40  brouard
                     37:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     38: 
1.272     brouard    39:   Revision 1.271  2017/06/27 10:17:50  brouard
                     40:   Summary: Some bug with rint
                     41: 
1.271     brouard    42:   Revision 1.270  2017/05/24 05:45:29  brouard
                     43:   *** empty log message ***
                     44: 
1.270     brouard    45:   Revision 1.269  2017/05/23 08:39:25  brouard
                     46:   Summary: Code into subroutine, cleanings
                     47: 
1.269     brouard    48:   Revision 1.268  2017/05/18 20:09:32  brouard
                     49:   Summary: backprojection and confidence intervals of backprevalence
                     50: 
1.268     brouard    51:   Revision 1.267  2017/05/13 10:25:05  brouard
                     52:   Summary: temporary save for backprojection
                     53: 
1.267     brouard    54:   Revision 1.266  2017/05/13 07:26:12  brouard
                     55:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     56: 
1.266     brouard    57:   Revision 1.265  2017/04/26 16:22:11  brouard
                     58:   Summary: imach 0.99r13 Some bugs fixed
                     59: 
1.265     brouard    60:   Revision 1.264  2017/04/26 06:01:29  brouard
                     61:   Summary: Labels in graphs
                     62: 
1.264     brouard    63:   Revision 1.263  2017/04/24 15:23:15  brouard
                     64:   Summary: to save
                     65: 
1.263     brouard    66:   Revision 1.262  2017/04/18 16:48:12  brouard
                     67:   *** empty log message ***
                     68: 
1.262     brouard    69:   Revision 1.261  2017/04/05 10:14:09  brouard
                     70:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     71: 
1.261     brouard    72:   Revision 1.260  2017/04/04 17:46:59  brouard
                     73:   Summary: Gnuplot indexations fixed (humm)
                     74: 
1.260     brouard    75:   Revision 1.259  2017/04/04 13:01:16  brouard
                     76:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     77: 
1.259     brouard    78:   Revision 1.258  2017/04/03 10:17:47  brouard
                     79:   Summary: Version 0.99r12
                     80: 
                     81:   Some cleanings, conformed with updated documentation.
                     82: 
1.258     brouard    83:   Revision 1.257  2017/03/29 16:53:30  brouard
                     84:   Summary: Temp
                     85: 
1.257     brouard    86:   Revision 1.256  2017/03/27 05:50:23  brouard
                     87:   Summary: Temporary
                     88: 
1.256     brouard    89:   Revision 1.255  2017/03/08 16:02:28  brouard
                     90:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     91: 
1.255     brouard    92:   Revision 1.254  2017/03/08 07:13:00  brouard
                     93:   Summary: Fixing data parameter line
                     94: 
1.254     brouard    95:   Revision 1.253  2016/12/15 11:59:41  brouard
                     96:   Summary: 0.99 in progress
                     97: 
1.253     brouard    98:   Revision 1.252  2016/09/15 21:15:37  brouard
                     99:   *** empty log message ***
                    100: 
1.252     brouard   101:   Revision 1.251  2016/09/15 15:01:13  brouard
                    102:   Summary: not working
                    103: 
1.251     brouard   104:   Revision 1.250  2016/09/08 16:07:27  brouard
                    105:   Summary: continue
                    106: 
1.250     brouard   107:   Revision 1.249  2016/09/07 17:14:18  brouard
                    108:   Summary: Starting values from frequencies
                    109: 
1.249     brouard   110:   Revision 1.248  2016/09/07 14:10:18  brouard
                    111:   *** empty log message ***
                    112: 
1.248     brouard   113:   Revision 1.247  2016/09/02 11:11:21  brouard
                    114:   *** empty log message ***
                    115: 
1.247     brouard   116:   Revision 1.246  2016/09/02 08:49:22  brouard
                    117:   *** empty log message ***
                    118: 
1.246     brouard   119:   Revision 1.245  2016/09/02 07:25:01  brouard
                    120:   *** empty log message ***
                    121: 
1.245     brouard   122:   Revision 1.244  2016/09/02 07:17:34  brouard
                    123:   *** empty log message ***
                    124: 
1.244     brouard   125:   Revision 1.243  2016/09/02 06:45:35  brouard
                    126:   *** empty log message ***
                    127: 
1.243     brouard   128:   Revision 1.242  2016/08/30 15:01:20  brouard
                    129:   Summary: Fixing a lots
                    130: 
1.242     brouard   131:   Revision 1.241  2016/08/29 17:17:25  brouard
                    132:   Summary: gnuplot problem in Back projection to fix
                    133: 
1.241     brouard   134:   Revision 1.240  2016/08/29 07:53:18  brouard
                    135:   Summary: Better
                    136: 
1.240     brouard   137:   Revision 1.239  2016/08/26 15:51:03  brouard
                    138:   Summary: Improvement in Powell output in order to copy and paste
                    139: 
                    140:   Author:
                    141: 
1.239     brouard   142:   Revision 1.238  2016/08/26 14:23:35  brouard
                    143:   Summary: Starting tests of 0.99
                    144: 
1.238     brouard   145:   Revision 1.237  2016/08/26 09:20:19  brouard
                    146:   Summary: to valgrind
                    147: 
1.237     brouard   148:   Revision 1.236  2016/08/25 10:50:18  brouard
                    149:   *** empty log message ***
                    150: 
1.236     brouard   151:   Revision 1.235  2016/08/25 06:59:23  brouard
                    152:   *** empty log message ***
                    153: 
1.235     brouard   154:   Revision 1.234  2016/08/23 16:51:20  brouard
                    155:   *** empty log message ***
                    156: 
1.234     brouard   157:   Revision 1.233  2016/08/23 07:40:50  brouard
                    158:   Summary: not working
                    159: 
1.233     brouard   160:   Revision 1.232  2016/08/22 14:20:21  brouard
                    161:   Summary: not working
                    162: 
1.232     brouard   163:   Revision 1.231  2016/08/22 07:17:15  brouard
                    164:   Summary: not working
                    165: 
1.231     brouard   166:   Revision 1.230  2016/08/22 06:55:53  brouard
                    167:   Summary: Not working
                    168: 
1.230     brouard   169:   Revision 1.229  2016/07/23 09:45:53  brouard
                    170:   Summary: Completing for func too
                    171: 
1.229     brouard   172:   Revision 1.228  2016/07/22 17:45:30  brouard
                    173:   Summary: Fixing some arrays, still debugging
                    174: 
1.227     brouard   175:   Revision 1.226  2016/07/12 18:42:34  brouard
                    176:   Summary: temp
                    177: 
1.226     brouard   178:   Revision 1.225  2016/07/12 08:40:03  brouard
                    179:   Summary: saving but not running
                    180: 
1.225     brouard   181:   Revision 1.224  2016/07/01 13:16:01  brouard
                    182:   Summary: Fixes
                    183: 
1.224     brouard   184:   Revision 1.223  2016/02/19 09:23:35  brouard
                    185:   Summary: temporary
                    186: 
1.223     brouard   187:   Revision 1.222  2016/02/17 08:14:50  brouard
                    188:   Summary: Probably last 0.98 stable version 0.98r6
                    189: 
1.222     brouard   190:   Revision 1.221  2016/02/15 23:35:36  brouard
                    191:   Summary: minor bug
                    192: 
1.220     brouard   193:   Revision 1.219  2016/02/15 00:48:12  brouard
                    194:   *** empty log message ***
                    195: 
1.219     brouard   196:   Revision 1.218  2016/02/12 11:29:23  brouard
                    197:   Summary: 0.99 Back projections
                    198: 
1.218     brouard   199:   Revision 1.217  2015/12/23 17:18:31  brouard
                    200:   Summary: Experimental backcast
                    201: 
1.217     brouard   202:   Revision 1.216  2015/12/18 17:32:11  brouard
                    203:   Summary: 0.98r4 Warning and status=-2
                    204: 
                    205:   Version 0.98r4 is now:
                    206:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    207:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    208:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    209: 
1.216     brouard   210:   Revision 1.215  2015/12/16 08:52:24  brouard
                    211:   Summary: 0.98r4 working
                    212: 
1.215     brouard   213:   Revision 1.214  2015/12/16 06:57:54  brouard
                    214:   Summary: temporary not working
                    215: 
1.214     brouard   216:   Revision 1.213  2015/12/11 18:22:17  brouard
                    217:   Summary: 0.98r4
                    218: 
1.213     brouard   219:   Revision 1.212  2015/11/21 12:47:24  brouard
                    220:   Summary: minor typo
                    221: 
1.212     brouard   222:   Revision 1.211  2015/11/21 12:41:11  brouard
                    223:   Summary: 0.98r3 with some graph of projected cross-sectional
                    224: 
                    225:   Author: Nicolas Brouard
                    226: 
1.211     brouard   227:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   228:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   229:   Summary: Adding ftolpl parameter
                    230:   Author: N Brouard
                    231: 
                    232:   We had difficulties to get smoothed confidence intervals. It was due
                    233:   to the period prevalence which wasn't computed accurately. The inner
                    234:   parameter ftolpl is now an outer parameter of the .imach parameter
                    235:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    236:   computation are long.
                    237: 
1.209     brouard   238:   Revision 1.208  2015/11/17 14:31:57  brouard
                    239:   Summary: temporary
                    240: 
1.208     brouard   241:   Revision 1.207  2015/10/27 17:36:57  brouard
                    242:   *** empty log message ***
                    243: 
1.207     brouard   244:   Revision 1.206  2015/10/24 07:14:11  brouard
                    245:   *** empty log message ***
                    246: 
1.206     brouard   247:   Revision 1.205  2015/10/23 15:50:53  brouard
                    248:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    249: 
1.205     brouard   250:   Revision 1.204  2015/10/01 16:20:26  brouard
                    251:   Summary: Some new graphs of contribution to likelihood
                    252: 
1.204     brouard   253:   Revision 1.203  2015/09/30 17:45:14  brouard
                    254:   Summary: looking at better estimation of the hessian
                    255: 
                    256:   Also a better criteria for convergence to the period prevalence And
                    257:   therefore adding the number of years needed to converge. (The
                    258:   prevalence in any alive state shold sum to one
                    259: 
1.203     brouard   260:   Revision 1.202  2015/09/22 19:45:16  brouard
                    261:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    262: 
1.202     brouard   263:   Revision 1.201  2015/09/15 17:34:58  brouard
                    264:   Summary: 0.98r0
                    265: 
                    266:   - Some new graphs like suvival functions
                    267:   - Some bugs fixed like model=1+age+V2.
                    268: 
1.201     brouard   269:   Revision 1.200  2015/09/09 16:53:55  brouard
                    270:   Summary: Big bug thanks to Flavia
                    271: 
                    272:   Even model=1+age+V2. did not work anymore
                    273: 
1.200     brouard   274:   Revision 1.199  2015/09/07 14:09:23  brouard
                    275:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    276: 
1.199     brouard   277:   Revision 1.198  2015/09/03 07:14:39  brouard
                    278:   Summary: 0.98q5 Flavia
                    279: 
1.198     brouard   280:   Revision 1.197  2015/09/01 18:24:39  brouard
                    281:   *** empty log message ***
                    282: 
1.197     brouard   283:   Revision 1.196  2015/08/18 23:17:52  brouard
                    284:   Summary: 0.98q5
                    285: 
1.196     brouard   286:   Revision 1.195  2015/08/18 16:28:39  brouard
                    287:   Summary: Adding a hack for testing purpose
                    288: 
                    289:   After reading the title, ftol and model lines, if the comment line has
                    290:   a q, starting with #q, the answer at the end of the run is quit. It
                    291:   permits to run test files in batch with ctest. The former workaround was
                    292:   $ echo q | imach foo.imach
                    293: 
1.195     brouard   294:   Revision 1.194  2015/08/18 13:32:00  brouard
                    295:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    296: 
1.194     brouard   297:   Revision 1.193  2015/08/04 07:17:42  brouard
                    298:   Summary: 0.98q4
                    299: 
1.193     brouard   300:   Revision 1.192  2015/07/16 16:49:02  brouard
                    301:   Summary: Fixing some outputs
                    302: 
1.192     brouard   303:   Revision 1.191  2015/07/14 10:00:33  brouard
                    304:   Summary: Some fixes
                    305: 
1.191     brouard   306:   Revision 1.190  2015/05/05 08:51:13  brouard
                    307:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    308: 
                    309:   Fix 1+age+.
                    310: 
1.190     brouard   311:   Revision 1.189  2015/04/30 14:45:16  brouard
                    312:   Summary: 0.98q2
                    313: 
1.189     brouard   314:   Revision 1.188  2015/04/30 08:27:53  brouard
                    315:   *** empty log message ***
                    316: 
1.188     brouard   317:   Revision 1.187  2015/04/29 09:11:15  brouard
                    318:   *** empty log message ***
                    319: 
1.187     brouard   320:   Revision 1.186  2015/04/23 12:01:52  brouard
                    321:   Summary: V1*age is working now, version 0.98q1
                    322: 
                    323:   Some codes had been disabled in order to simplify and Vn*age was
                    324:   working in the optimization phase, ie, giving correct MLE parameters,
                    325:   but, as usual, outputs were not correct and program core dumped.
                    326: 
1.186     brouard   327:   Revision 1.185  2015/03/11 13:26:42  brouard
                    328:   Summary: Inclusion of compile and links command line for Intel Compiler
                    329: 
1.185     brouard   330:   Revision 1.184  2015/03/11 11:52:39  brouard
                    331:   Summary: Back from Windows 8. Intel Compiler
                    332: 
1.184     brouard   333:   Revision 1.183  2015/03/10 20:34:32  brouard
                    334:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    335: 
                    336:   We use directest instead of original Powell test; probably no
                    337:   incidence on the results, but better justifications;
                    338:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    339:   wrong results.
                    340: 
1.183     brouard   341:   Revision 1.182  2015/02/12 08:19:57  brouard
                    342:   Summary: Trying to keep directest which seems simpler and more general
                    343:   Author: Nicolas Brouard
                    344: 
1.182     brouard   345:   Revision 1.181  2015/02/11 23:22:24  brouard
                    346:   Summary: Comments on Powell added
                    347: 
                    348:   Author:
                    349: 
1.181     brouard   350:   Revision 1.180  2015/02/11 17:33:45  brouard
                    351:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    352: 
1.180     brouard   353:   Revision 1.179  2015/01/04 09:57:06  brouard
                    354:   Summary: back to OS/X
                    355: 
1.179     brouard   356:   Revision 1.178  2015/01/04 09:35:48  brouard
                    357:   *** empty log message ***
                    358: 
1.178     brouard   359:   Revision 1.177  2015/01/03 18:40:56  brouard
                    360:   Summary: Still testing ilc32 on OSX
                    361: 
1.177     brouard   362:   Revision 1.176  2015/01/03 16:45:04  brouard
                    363:   *** empty log message ***
                    364: 
1.176     brouard   365:   Revision 1.175  2015/01/03 16:33:42  brouard
                    366:   *** empty log message ***
                    367: 
1.175     brouard   368:   Revision 1.174  2015/01/03 16:15:49  brouard
                    369:   Summary: Still in cross-compilation
                    370: 
1.174     brouard   371:   Revision 1.173  2015/01/03 12:06:26  brouard
                    372:   Summary: trying to detect cross-compilation
                    373: 
1.173     brouard   374:   Revision 1.172  2014/12/27 12:07:47  brouard
                    375:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    376: 
1.172     brouard   377:   Revision 1.171  2014/12/23 13:26:59  brouard
                    378:   Summary: Back from Visual C
                    379: 
                    380:   Still problem with utsname.h on Windows
                    381: 
1.171     brouard   382:   Revision 1.170  2014/12/23 11:17:12  brouard
                    383:   Summary: Cleaning some \%% back to %%
                    384: 
                    385:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    386: 
1.170     brouard   387:   Revision 1.169  2014/12/22 23:08:31  brouard
                    388:   Summary: 0.98p
                    389: 
                    390:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    391: 
1.169     brouard   392:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   393:   Summary: update
1.169     brouard   394: 
1.168     brouard   395:   Revision 1.167  2014/12/22 13:50:56  brouard
                    396:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    397: 
                    398:   Testing on Linux 64
                    399: 
1.167     brouard   400:   Revision 1.166  2014/12/22 11:40:47  brouard
                    401:   *** empty log message ***
                    402: 
1.166     brouard   403:   Revision 1.165  2014/12/16 11:20:36  brouard
                    404:   Summary: After compiling on Visual C
                    405: 
                    406:   * imach.c (Module): Merging 1.61 to 1.162
                    407: 
1.165     brouard   408:   Revision 1.164  2014/12/16 10:52:11  brouard
                    409:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    410: 
                    411:   * imach.c (Module): Merging 1.61 to 1.162
                    412: 
1.164     brouard   413:   Revision 1.163  2014/12/16 10:30:11  brouard
                    414:   * imach.c (Module): Merging 1.61 to 1.162
                    415: 
1.163     brouard   416:   Revision 1.162  2014/09/25 11:43:39  brouard
                    417:   Summary: temporary backup 0.99!
                    418: 
1.162     brouard   419:   Revision 1.1  2014/09/16 11:06:58  brouard
                    420:   Summary: With some code (wrong) for nlopt
                    421: 
                    422:   Author:
                    423: 
                    424:   Revision 1.161  2014/09/15 20:41:41  brouard
                    425:   Summary: Problem with macro SQR on Intel compiler
                    426: 
1.161     brouard   427:   Revision 1.160  2014/09/02 09:24:05  brouard
                    428:   *** empty log message ***
                    429: 
1.160     brouard   430:   Revision 1.159  2014/09/01 10:34:10  brouard
                    431:   Summary: WIN32
                    432:   Author: Brouard
                    433: 
1.159     brouard   434:   Revision 1.158  2014/08/27 17:11:51  brouard
                    435:   *** empty log message ***
                    436: 
1.158     brouard   437:   Revision 1.157  2014/08/27 16:26:55  brouard
                    438:   Summary: Preparing windows Visual studio version
                    439:   Author: Brouard
                    440: 
                    441:   In order to compile on Visual studio, time.h is now correct and time_t
                    442:   and tm struct should be used. difftime should be used but sometimes I
                    443:   just make the differences in raw time format (time(&now).
                    444:   Trying to suppress #ifdef LINUX
                    445:   Add xdg-open for __linux in order to open default browser.
                    446: 
1.157     brouard   447:   Revision 1.156  2014/08/25 20:10:10  brouard
                    448:   *** empty log message ***
                    449: 
1.156     brouard   450:   Revision 1.155  2014/08/25 18:32:34  brouard
                    451:   Summary: New compile, minor changes
                    452:   Author: Brouard
                    453: 
1.155     brouard   454:   Revision 1.154  2014/06/20 17:32:08  brouard
                    455:   Summary: Outputs now all graphs of convergence to period prevalence
                    456: 
1.154     brouard   457:   Revision 1.153  2014/06/20 16:45:46  brouard
                    458:   Summary: If 3 live state, convergence to period prevalence on same graph
                    459:   Author: Brouard
                    460: 
1.153     brouard   461:   Revision 1.152  2014/06/18 17:54:09  brouard
                    462:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    463: 
1.152     brouard   464:   Revision 1.151  2014/06/18 16:43:30  brouard
                    465:   *** empty log message ***
                    466: 
1.151     brouard   467:   Revision 1.150  2014/06/18 16:42:35  brouard
                    468:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    469:   Author: brouard
                    470: 
1.150     brouard   471:   Revision 1.149  2014/06/18 15:51:14  brouard
                    472:   Summary: Some fixes in parameter files errors
                    473:   Author: Nicolas Brouard
                    474: 
1.149     brouard   475:   Revision 1.148  2014/06/17 17:38:48  brouard
                    476:   Summary: Nothing new
                    477:   Author: Brouard
                    478: 
                    479:   Just a new packaging for OS/X version 0.98nS
                    480: 
1.148     brouard   481:   Revision 1.147  2014/06/16 10:33:11  brouard
                    482:   *** empty log message ***
                    483: 
1.147     brouard   484:   Revision 1.146  2014/06/16 10:20:28  brouard
                    485:   Summary: Merge
                    486:   Author: Brouard
                    487: 
                    488:   Merge, before building revised version.
                    489: 
1.146     brouard   490:   Revision 1.145  2014/06/10 21:23:15  brouard
                    491:   Summary: Debugging with valgrind
                    492:   Author: Nicolas Brouard
                    493: 
                    494:   Lot of changes in order to output the results with some covariates
                    495:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    496:   improve the code.
                    497:   No more memory valgrind error but a lot has to be done in order to
                    498:   continue the work of splitting the code into subroutines.
                    499:   Also, decodemodel has been improved. Tricode is still not
                    500:   optimal. nbcode should be improved. Documentation has been added in
                    501:   the source code.
                    502: 
1.144     brouard   503:   Revision 1.143  2014/01/26 09:45:38  brouard
                    504:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    505: 
                    506:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    507:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    508: 
1.143     brouard   509:   Revision 1.142  2014/01/26 03:57:36  brouard
                    510:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    511: 
                    512:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    513: 
1.142     brouard   514:   Revision 1.141  2014/01/26 02:42:01  brouard
                    515:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    516: 
1.141     brouard   517:   Revision 1.140  2011/09/02 10:37:54  brouard
                    518:   Summary: times.h is ok with mingw32 now.
                    519: 
1.140     brouard   520:   Revision 1.139  2010/06/14 07:50:17  brouard
                    521:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    522:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    523: 
1.139     brouard   524:   Revision 1.138  2010/04/30 18:19:40  brouard
                    525:   *** empty log message ***
                    526: 
1.138     brouard   527:   Revision 1.137  2010/04/29 18:11:38  brouard
                    528:   (Module): Checking covariates for more complex models
                    529:   than V1+V2. A lot of change to be done. Unstable.
                    530: 
1.137     brouard   531:   Revision 1.136  2010/04/26 20:30:53  brouard
                    532:   (Module): merging some libgsl code. Fixing computation
                    533:   of likelione (using inter/intrapolation if mle = 0) in order to
                    534:   get same likelihood as if mle=1.
                    535:   Some cleaning of code and comments added.
                    536: 
1.136     brouard   537:   Revision 1.135  2009/10/29 15:33:14  brouard
                    538:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    539: 
1.135     brouard   540:   Revision 1.134  2009/10/29 13:18:53  brouard
                    541:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    542: 
1.134     brouard   543:   Revision 1.133  2009/07/06 10:21:25  brouard
                    544:   just nforces
                    545: 
1.133     brouard   546:   Revision 1.132  2009/07/06 08:22:05  brouard
                    547:   Many tings
                    548: 
1.132     brouard   549:   Revision 1.131  2009/06/20 16:22:47  brouard
                    550:   Some dimensions resccaled
                    551: 
1.131     brouard   552:   Revision 1.130  2009/05/26 06:44:34  brouard
                    553:   (Module): Max Covariate is now set to 20 instead of 8. A
                    554:   lot of cleaning with variables initialized to 0. Trying to make
                    555:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    556: 
1.130     brouard   557:   Revision 1.129  2007/08/31 13:49:27  lievre
                    558:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    559: 
1.129     lievre    560:   Revision 1.128  2006/06/30 13:02:05  brouard
                    561:   (Module): Clarifications on computing e.j
                    562: 
1.128     brouard   563:   Revision 1.127  2006/04/28 18:11:50  brouard
                    564:   (Module): Yes the sum of survivors was wrong since
                    565:   imach-114 because nhstepm was no more computed in the age
                    566:   loop. Now we define nhstepma in the age loop.
                    567:   (Module): In order to speed up (in case of numerous covariates) we
                    568:   compute health expectancies (without variances) in a first step
                    569:   and then all the health expectancies with variances or standard
                    570:   deviation (needs data from the Hessian matrices) which slows the
                    571:   computation.
                    572:   In the future we should be able to stop the program is only health
                    573:   expectancies and graph are needed without standard deviations.
                    574: 
1.127     brouard   575:   Revision 1.126  2006/04/28 17:23:28  brouard
                    576:   (Module): Yes the sum of survivors was wrong since
                    577:   imach-114 because nhstepm was no more computed in the age
                    578:   loop. Now we define nhstepma in the age loop.
                    579:   Version 0.98h
                    580: 
1.126     brouard   581:   Revision 1.125  2006/04/04 15:20:31  lievre
                    582:   Errors in calculation of health expectancies. Age was not initialized.
                    583:   Forecasting file added.
                    584: 
                    585:   Revision 1.124  2006/03/22 17:13:53  lievre
                    586:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    587:   The log-likelihood is printed in the log file
                    588: 
                    589:   Revision 1.123  2006/03/20 10:52:43  brouard
                    590:   * imach.c (Module): <title> changed, corresponds to .htm file
                    591:   name. <head> headers where missing.
                    592: 
                    593:   * imach.c (Module): Weights can have a decimal point as for
                    594:   English (a comma might work with a correct LC_NUMERIC environment,
                    595:   otherwise the weight is truncated).
                    596:   Modification of warning when the covariates values are not 0 or
                    597:   1.
                    598:   Version 0.98g
                    599: 
                    600:   Revision 1.122  2006/03/20 09:45:41  brouard
                    601:   (Module): Weights can have a decimal point as for
                    602:   English (a comma might work with a correct LC_NUMERIC environment,
                    603:   otherwise the weight is truncated).
                    604:   Modification of warning when the covariates values are not 0 or
                    605:   1.
                    606:   Version 0.98g
                    607: 
                    608:   Revision 1.121  2006/03/16 17:45:01  lievre
                    609:   * imach.c (Module): Comments concerning covariates added
                    610: 
                    611:   * imach.c (Module): refinements in the computation of lli if
                    612:   status=-2 in order to have more reliable computation if stepm is
                    613:   not 1 month. Version 0.98f
                    614: 
                    615:   Revision 1.120  2006/03/16 15:10:38  lievre
                    616:   (Module): refinements in the computation of lli if
                    617:   status=-2 in order to have more reliable computation if stepm is
                    618:   not 1 month. Version 0.98f
                    619: 
                    620:   Revision 1.119  2006/03/15 17:42:26  brouard
                    621:   (Module): Bug if status = -2, the loglikelihood was
                    622:   computed as likelihood omitting the logarithm. Version O.98e
                    623: 
                    624:   Revision 1.118  2006/03/14 18:20:07  brouard
                    625:   (Module): varevsij Comments added explaining the second
                    626:   table of variances if popbased=1 .
                    627:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    628:   (Module): Function pstamp added
                    629:   (Module): Version 0.98d
                    630: 
                    631:   Revision 1.117  2006/03/14 17:16:22  brouard
                    632:   (Module): varevsij Comments added explaining the second
                    633:   table of variances if popbased=1 .
                    634:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    635:   (Module): Function pstamp added
                    636:   (Module): Version 0.98d
                    637: 
                    638:   Revision 1.116  2006/03/06 10:29:27  brouard
                    639:   (Module): Variance-covariance wrong links and
                    640:   varian-covariance of ej. is needed (Saito).
                    641: 
                    642:   Revision 1.115  2006/02/27 12:17:45  brouard
                    643:   (Module): One freematrix added in mlikeli! 0.98c
                    644: 
                    645:   Revision 1.114  2006/02/26 12:57:58  brouard
                    646:   (Module): Some improvements in processing parameter
                    647:   filename with strsep.
                    648: 
                    649:   Revision 1.113  2006/02/24 14:20:24  brouard
                    650:   (Module): Memory leaks checks with valgrind and:
                    651:   datafile was not closed, some imatrix were not freed and on matrix
                    652:   allocation too.
                    653: 
                    654:   Revision 1.112  2006/01/30 09:55:26  brouard
                    655:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    656: 
                    657:   Revision 1.111  2006/01/25 20:38:18  brouard
                    658:   (Module): Lots of cleaning and bugs added (Gompertz)
                    659:   (Module): Comments can be added in data file. Missing date values
                    660:   can be a simple dot '.'.
                    661: 
                    662:   Revision 1.110  2006/01/25 00:51:50  brouard
                    663:   (Module): Lots of cleaning and bugs added (Gompertz)
                    664: 
                    665:   Revision 1.109  2006/01/24 19:37:15  brouard
                    666:   (Module): Comments (lines starting with a #) are allowed in data.
                    667: 
                    668:   Revision 1.108  2006/01/19 18:05:42  lievre
                    669:   Gnuplot problem appeared...
                    670:   To be fixed
                    671: 
                    672:   Revision 1.107  2006/01/19 16:20:37  brouard
                    673:   Test existence of gnuplot in imach path
                    674: 
                    675:   Revision 1.106  2006/01/19 13:24:36  brouard
                    676:   Some cleaning and links added in html output
                    677: 
                    678:   Revision 1.105  2006/01/05 20:23:19  lievre
                    679:   *** empty log message ***
                    680: 
                    681:   Revision 1.104  2005/09/30 16:11:43  lievre
                    682:   (Module): sump fixed, loop imx fixed, and simplifications.
                    683:   (Module): If the status is missing at the last wave but we know
                    684:   that the person is alive, then we can code his/her status as -2
                    685:   (instead of missing=-1 in earlier versions) and his/her
                    686:   contributions to the likelihood is 1 - Prob of dying from last
                    687:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    688:   the healthy state at last known wave). Version is 0.98
                    689: 
                    690:   Revision 1.103  2005/09/30 15:54:49  lievre
                    691:   (Module): sump fixed, loop imx fixed, and simplifications.
                    692: 
                    693:   Revision 1.102  2004/09/15 17:31:30  brouard
                    694:   Add the possibility to read data file including tab characters.
                    695: 
                    696:   Revision 1.101  2004/09/15 10:38:38  brouard
                    697:   Fix on curr_time
                    698: 
                    699:   Revision 1.100  2004/07/12 18:29:06  brouard
                    700:   Add version for Mac OS X. Just define UNIX in Makefile
                    701: 
                    702:   Revision 1.99  2004/06/05 08:57:40  brouard
                    703:   *** empty log message ***
                    704: 
                    705:   Revision 1.98  2004/05/16 15:05:56  brouard
                    706:   New version 0.97 . First attempt to estimate force of mortality
                    707:   directly from the data i.e. without the need of knowing the health
                    708:   state at each age, but using a Gompertz model: log u =a + b*age .
                    709:   This is the basic analysis of mortality and should be done before any
                    710:   other analysis, in order to test if the mortality estimated from the
                    711:   cross-longitudinal survey is different from the mortality estimated
                    712:   from other sources like vital statistic data.
                    713: 
                    714:   The same imach parameter file can be used but the option for mle should be -3.
                    715: 
1.133     brouard   716:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   717:   former routines in order to include the new code within the former code.
                    718: 
                    719:   The output is very simple: only an estimate of the intercept and of
                    720:   the slope with 95% confident intervals.
                    721: 
                    722:   Current limitations:
                    723:   A) Even if you enter covariates, i.e. with the
                    724:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    725:   B) There is no computation of Life Expectancy nor Life Table.
                    726: 
                    727:   Revision 1.97  2004/02/20 13:25:42  lievre
                    728:   Version 0.96d. Population forecasting command line is (temporarily)
                    729:   suppressed.
                    730: 
                    731:   Revision 1.96  2003/07/15 15:38:55  brouard
                    732:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    733:   rewritten within the same printf. Workaround: many printfs.
                    734: 
                    735:   Revision 1.95  2003/07/08 07:54:34  brouard
                    736:   * imach.c (Repository):
                    737:   (Repository): Using imachwizard code to output a more meaningful covariance
                    738:   matrix (cov(a12,c31) instead of numbers.
                    739: 
                    740:   Revision 1.94  2003/06/27 13:00:02  brouard
                    741:   Just cleaning
                    742: 
                    743:   Revision 1.93  2003/06/25 16:33:55  brouard
                    744:   (Module): On windows (cygwin) function asctime_r doesn't
                    745:   exist so I changed back to asctime which exists.
                    746:   (Module): Version 0.96b
                    747: 
                    748:   Revision 1.92  2003/06/25 16:30:45  brouard
                    749:   (Module): On windows (cygwin) function asctime_r doesn't
                    750:   exist so I changed back to asctime which exists.
                    751: 
                    752:   Revision 1.91  2003/06/25 15:30:29  brouard
                    753:   * imach.c (Repository): Duplicated warning errors corrected.
                    754:   (Repository): Elapsed time after each iteration is now output. It
                    755:   helps to forecast when convergence will be reached. Elapsed time
                    756:   is stamped in powell.  We created a new html file for the graphs
                    757:   concerning matrix of covariance. It has extension -cov.htm.
                    758: 
                    759:   Revision 1.90  2003/06/24 12:34:15  brouard
                    760:   (Module): Some bugs corrected for windows. Also, when
                    761:   mle=-1 a template is output in file "or"mypar.txt with the design
                    762:   of the covariance matrix to be input.
                    763: 
                    764:   Revision 1.89  2003/06/24 12:30:52  brouard
                    765:   (Module): Some bugs corrected for windows. Also, when
                    766:   mle=-1 a template is output in file "or"mypar.txt with the design
                    767:   of the covariance matrix to be input.
                    768: 
                    769:   Revision 1.88  2003/06/23 17:54:56  brouard
                    770:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    771: 
                    772:   Revision 1.87  2003/06/18 12:26:01  brouard
                    773:   Version 0.96
                    774: 
                    775:   Revision 1.86  2003/06/17 20:04:08  brouard
                    776:   (Module): Change position of html and gnuplot routines and added
                    777:   routine fileappend.
                    778: 
                    779:   Revision 1.85  2003/06/17 13:12:43  brouard
                    780:   * imach.c (Repository): Check when date of death was earlier that
                    781:   current date of interview. It may happen when the death was just
                    782:   prior to the death. In this case, dh was negative and likelihood
                    783:   was wrong (infinity). We still send an "Error" but patch by
                    784:   assuming that the date of death was just one stepm after the
                    785:   interview.
                    786:   (Repository): Because some people have very long ID (first column)
                    787:   we changed int to long in num[] and we added a new lvector for
                    788:   memory allocation. But we also truncated to 8 characters (left
                    789:   truncation)
                    790:   (Repository): No more line truncation errors.
                    791: 
                    792:   Revision 1.84  2003/06/13 21:44:43  brouard
                    793:   * imach.c (Repository): Replace "freqsummary" at a correct
                    794:   place. It differs from routine "prevalence" which may be called
                    795:   many times. Probs is memory consuming and must be used with
                    796:   parcimony.
                    797:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    798: 
                    799:   Revision 1.83  2003/06/10 13:39:11  lievre
                    800:   *** empty log message ***
                    801: 
                    802:   Revision 1.82  2003/06/05 15:57:20  brouard
                    803:   Add log in  imach.c and  fullversion number is now printed.
                    804: 
                    805: */
                    806: /*
                    807:    Interpolated Markov Chain
                    808: 
                    809:   Short summary of the programme:
                    810:   
1.227     brouard   811:   This program computes Healthy Life Expectancies or State-specific
                    812:   (if states aren't health statuses) Expectancies from
                    813:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    814: 
                    815:   -1- a first survey ("cross") where individuals from different ages
                    816:   are interviewed on their health status or degree of disability (in
                    817:   the case of a health survey which is our main interest)
                    818: 
                    819:   -2- at least a second wave of interviews ("longitudinal") which
                    820:   measure each change (if any) in individual health status.  Health
                    821:   expectancies are computed from the time spent in each health state
                    822:   according to a model. More health states you consider, more time is
                    823:   necessary to reach the Maximum Likelihood of the parameters involved
                    824:   in the model.  The simplest model is the multinomial logistic model
                    825:   where pij is the probability to be observed in state j at the second
                    826:   wave conditional to be observed in state i at the first
                    827:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    828:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    829:   have a more complex model than "constant and age", you should modify
                    830:   the program where the markup *Covariates have to be included here
                    831:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   832:   convergence.
                    833: 
                    834:   The advantage of this computer programme, compared to a simple
                    835:   multinomial logistic model, is clear when the delay between waves is not
                    836:   identical for each individual. Also, if a individual missed an
                    837:   intermediate interview, the information is lost, but taken into
                    838:   account using an interpolation or extrapolation.  
                    839: 
                    840:   hPijx is the probability to be observed in state i at age x+h
                    841:   conditional to the observed state i at age x. The delay 'h' can be
                    842:   split into an exact number (nh*stepm) of unobserved intermediate
                    843:   states. This elementary transition (by month, quarter,
                    844:   semester or year) is modelled as a multinomial logistic.  The hPx
                    845:   matrix is simply the matrix product of nh*stepm elementary matrices
                    846:   and the contribution of each individual to the likelihood is simply
                    847:   hPijx.
                    848: 
                    849:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   850:   of the life expectancies. It also computes the period (stable) prevalence.
                    851: 
                    852: Back prevalence and projections:
1.227     brouard   853: 
                    854:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    855:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    856:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    857:    mobilavproj)
                    858: 
                    859:     Computes the back prevalence limit for any combination of
                    860:     covariate values k at any age between ageminpar and agemaxpar and
                    861:     returns it in **bprlim. In the loops,
                    862: 
                    863:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    864:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    865: 
                    866:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   867:    Computes for any combination of covariates k and any age between bage and fage 
                    868:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    869:                        oldm=oldms;savm=savms;
1.227     brouard   870: 
1.267     brouard   871:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   872:      Computes the transition matrix starting at age 'age' over
                    873:      'nhstepm*hstepm*stepm' months (i.e. until
                    874:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   875:      nhstepm*hstepm matrices. 
                    876: 
                    877:      Returns p3mat[i][j][h] after calling
                    878:      p3mat[i][j][h]=matprod2(newm,
                    879:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    880:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    881:      oldm);
1.226     brouard   882: 
                    883: Important routines
                    884: 
                    885: - func (or funcone), computes logit (pij) distinguishing
                    886:   o fixed variables (single or product dummies or quantitative);
                    887:   o varying variables by:
                    888:    (1) wave (single, product dummies, quantitative), 
                    889:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    890:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    891:        % varying dummy (not done) or quantitative (not done);
                    892: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    893:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    894: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    895:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    896:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   897: 
1.226     brouard   898: 
                    899:   
1.133     brouard   900:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    901:            Institut national d'études démographiques, Paris.
1.126     brouard   902:   This software have been partly granted by Euro-REVES, a concerted action
                    903:   from the European Union.
                    904:   It is copyrighted identically to a GNU software product, ie programme and
                    905:   software can be distributed freely for non commercial use. Latest version
                    906:   can be accessed at http://euroreves.ined.fr/imach .
                    907: 
                    908:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    909:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    910:   
                    911:   **********************************************************************/
                    912: /*
                    913:   main
                    914:   read parameterfile
                    915:   read datafile
                    916:   concatwav
                    917:   freqsummary
                    918:   if (mle >= 1)
                    919:     mlikeli
                    920:   print results files
                    921:   if mle==1 
                    922:      computes hessian
                    923:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    924:       begin-prev-date,...
                    925:   open gnuplot file
                    926:   open html file
1.145     brouard   927:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    928:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    929:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    930:     freexexit2 possible for memory heap.
                    931: 
                    932:   h Pij x                         | pij_nom  ficrestpij
                    933:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    934:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    935:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    936: 
                    937:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    938:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    939:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    940:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    941:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    942: 
1.126     brouard   943:   forecasting if prevfcast==1 prevforecast call prevalence()
                    944:   health expectancies
                    945:   Variance-covariance of DFLE
                    946:   prevalence()
                    947:    movingaverage()
                    948:   varevsij() 
                    949:   if popbased==1 varevsij(,popbased)
                    950:   total life expectancies
                    951:   Variance of period (stable) prevalence
                    952:  end
                    953: */
                    954: 
1.187     brouard   955: /* #define DEBUG */
                    956: /* #define DEBUGBRENT */
1.203     brouard   957: /* #define DEBUGLINMIN */
                    958: /* #define DEBUGHESS */
                    959: #define DEBUGHESSIJ
1.224     brouard   960: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   961: #define POWELL /* Instead of NLOPT */
1.224     brouard   962: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   963: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    964: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   965: 
                    966: #include <math.h>
                    967: #include <stdio.h>
                    968: #include <stdlib.h>
                    969: #include <string.h>
1.226     brouard   970: #include <ctype.h>
1.159     brouard   971: 
                    972: #ifdef _WIN32
                    973: #include <io.h>
1.172     brouard   974: #include <windows.h>
                    975: #include <tchar.h>
1.159     brouard   976: #else
1.126     brouard   977: #include <unistd.h>
1.159     brouard   978: #endif
1.126     brouard   979: 
                    980: #include <limits.h>
                    981: #include <sys/types.h>
1.171     brouard   982: 
                    983: #if defined(__GNUC__)
                    984: #include <sys/utsname.h> /* Doesn't work on Windows */
                    985: #endif
                    986: 
1.126     brouard   987: #include <sys/stat.h>
                    988: #include <errno.h>
1.159     brouard   989: /* extern int errno; */
1.126     brouard   990: 
1.157     brouard   991: /* #ifdef LINUX */
                    992: /* #include <time.h> */
                    993: /* #include "timeval.h" */
                    994: /* #else */
                    995: /* #include <sys/time.h> */
                    996: /* #endif */
                    997: 
1.126     brouard   998: #include <time.h>
                    999: 
1.136     brouard  1000: #ifdef GSL
                   1001: #include <gsl/gsl_errno.h>
                   1002: #include <gsl/gsl_multimin.h>
                   1003: #endif
                   1004: 
1.167     brouard  1005: 
1.162     brouard  1006: #ifdef NLOPT
                   1007: #include <nlopt.h>
                   1008: typedef struct {
                   1009:   double (* function)(double [] );
                   1010: } myfunc_data ;
                   1011: #endif
                   1012: 
1.126     brouard  1013: /* #include <libintl.h> */
                   1014: /* #define _(String) gettext (String) */
                   1015: 
1.251     brouard  1016: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1017: 
                   1018: #define GNUPLOTPROGRAM "gnuplot"
                   1019: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1020: #define FILENAMELENGTH 132
                   1021: 
                   1022: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1023: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1024: 
1.144     brouard  1025: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1026: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1027: 
                   1028: #define NINTERVMAX 8
1.144     brouard  1029: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1030: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1031: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1032: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1033: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1034: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1035: #define MAXN 20000
1.144     brouard  1036: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1037: /* #define AGESUP 130 */
                   1038: #define AGESUP 150
1.268     brouard  1039: #define AGEINF 0
1.218     brouard  1040: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1041: #define AGEBASE 40
1.194     brouard  1042: #define AGEOVERFLOW 1.e20
1.164     brouard  1043: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1044: #ifdef _WIN32
                   1045: #define DIRSEPARATOR '\\'
                   1046: #define CHARSEPARATOR "\\"
                   1047: #define ODIRSEPARATOR '/'
                   1048: #else
1.126     brouard  1049: #define DIRSEPARATOR '/'
                   1050: #define CHARSEPARATOR "/"
                   1051: #define ODIRSEPARATOR '\\'
                   1052: #endif
                   1053: 
1.283   ! brouard  1054: /* $Id: imach.c,v 1.282 2018/02/27 22:50:02 brouard Exp $ */
1.126     brouard  1055: /* $State: Exp $ */
1.196     brouard  1056: #include "version.h"
                   1057: char version[]=__IMACH_VERSION__;
1.283   ! brouard  1058: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
        !          1059: char fullversion[]="$Revision: 1.282 $ $Date: 2018/02/27 22:50:02 $"; 
1.126     brouard  1060: char strstart[80];
                   1061: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1062: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1063: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1064: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1065: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1066: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1067: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1068: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1069: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1070: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1071: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1072: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1073: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1074: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1075: int nsd=0; /**< Total number of single dummy variables (output) */
                   1076: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1077: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1078: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1079: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1080: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1081: int cptcov=0; /* Working variable */
1.218     brouard  1082: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1083: int npar=NPARMAX;
                   1084: int nlstate=2; /* Number of live states */
                   1085: int ndeath=1; /* Number of dead states */
1.130     brouard  1086: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1087: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1088: int popbased=0;
                   1089: 
                   1090: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1091: int maxwav=0; /* Maxim number of waves */
                   1092: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1093: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1094: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1095:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1096: int mle=1, weightopt=0;
1.126     brouard  1097: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1098: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1099: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1100:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1101: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1102: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1103: 
1.130     brouard  1104: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1105: double **matprod2(); /* test */
1.126     brouard  1106: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1107: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1108: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1109: 
1.136     brouard  1110: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1111: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1112: FILE *ficlog, *ficrespow;
1.130     brouard  1113: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1114: double fretone; /* Only one call to likelihood */
1.130     brouard  1115: long ipmx=0; /* Number of contributions */
1.126     brouard  1116: double sw; /* Sum of weights */
                   1117: char filerespow[FILENAMELENGTH];
                   1118: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1119: FILE *ficresilk;
                   1120: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1121: FILE *ficresprobmorprev;
                   1122: FILE *fichtm, *fichtmcov; /* Html File */
                   1123: FILE *ficreseij;
                   1124: char filerese[FILENAMELENGTH];
                   1125: FILE *ficresstdeij;
                   1126: char fileresstde[FILENAMELENGTH];
                   1127: FILE *ficrescveij;
                   1128: char filerescve[FILENAMELENGTH];
                   1129: FILE  *ficresvij;
                   1130: char fileresv[FILENAMELENGTH];
1.269     brouard  1131: 
1.126     brouard  1132: char title[MAXLINE];
1.234     brouard  1133: char model[MAXLINE]; /**< The model line */
1.217     brouard  1134: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1135: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1136: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1137: char command[FILENAMELENGTH];
                   1138: int  outcmd=0;
                   1139: 
1.217     brouard  1140: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1141: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1142: char filelog[FILENAMELENGTH]; /* Log file */
                   1143: char filerest[FILENAMELENGTH];
                   1144: char fileregp[FILENAMELENGTH];
                   1145: char popfile[FILENAMELENGTH];
                   1146: 
                   1147: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1148: 
1.157     brouard  1149: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1150: /* struct timezone tzp; */
                   1151: /* extern int gettimeofday(); */
                   1152: struct tm tml, *gmtime(), *localtime();
                   1153: 
                   1154: extern time_t time();
                   1155: 
                   1156: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1157: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1158: struct tm tm;
                   1159: 
1.126     brouard  1160: char strcurr[80], strfor[80];
                   1161: 
                   1162: char *endptr;
                   1163: long lval;
                   1164: double dval;
                   1165: 
                   1166: #define NR_END 1
                   1167: #define FREE_ARG char*
                   1168: #define FTOL 1.0e-10
                   1169: 
                   1170: #define NRANSI 
1.240     brouard  1171: #define ITMAX 200
                   1172: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1173: 
                   1174: #define TOL 2.0e-4 
                   1175: 
                   1176: #define CGOLD 0.3819660 
                   1177: #define ZEPS 1.0e-10 
                   1178: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1179: 
                   1180: #define GOLD 1.618034 
                   1181: #define GLIMIT 100.0 
                   1182: #define TINY 1.0e-20 
                   1183: 
                   1184: static double maxarg1,maxarg2;
                   1185: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1186: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1187:   
                   1188: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1189: #define rint(a) floor(a+0.5)
1.166     brouard  1190: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1191: #define mytinydouble 1.0e-16
1.166     brouard  1192: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1193: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1194: /* static double dsqrarg; */
                   1195: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1196: static double sqrarg;
                   1197: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1198: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1199: int agegomp= AGEGOMP;
                   1200: 
                   1201: int imx; 
                   1202: int stepm=1;
                   1203: /* Stepm, step in month: minimum step interpolation*/
                   1204: 
                   1205: int estepm;
                   1206: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1207: 
                   1208: int m,nb;
                   1209: long *num;
1.197     brouard  1210: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1211: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1212:                   covariate for which somebody answered excluding 
                   1213:                   undefined. Usually 2: 0 and 1. */
                   1214: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1215:                             covariate for which somebody answered including 
                   1216:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1217: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1218: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1219: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1220: double *ageexmed,*agecens;
                   1221: double dateintmean=0;
                   1222: 
                   1223: double *weight;
                   1224: int **s; /* Status */
1.141     brouard  1225: double *agedc;
1.145     brouard  1226: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1227:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1228:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1229: double **coqvar; /* Fixed quantitative covariate nqv */
                   1230: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1231: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1232: double  idx; 
                   1233: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1234: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1235: /*k          1  2   3   4     5    6    7     8    9 */
                   1236: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1237: /* Tndvar[k]    1   2   3               4          5 */
                   1238: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1239: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1240: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1241: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1242: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1243: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1244: /* Tprod[i]=k           4               7            */
                   1245: /* Tage[i]=k                  5               8      */
                   1246: /* */
                   1247: /* Type                    */
                   1248: /* V         1  2  3  4  5 */
                   1249: /*           F  F  V  V  V */
                   1250: /*           D  Q  D  D  Q */
                   1251: /*                         */
                   1252: int *TvarsD;
                   1253: int *TvarsDind;
                   1254: int *TvarsQ;
                   1255: int *TvarsQind;
                   1256: 
1.235     brouard  1257: #define MAXRESULTLINES 10
                   1258: int nresult=0;
1.258     brouard  1259: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1260: int TKresult[MAXRESULTLINES];
1.237     brouard  1261: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1262: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1263: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1264: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1265: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1266: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1267: 
1.234     brouard  1268: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1269: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1270: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1271: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1272: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1273: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1274: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1275: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1276: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1277: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1278: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1279: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1280: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1281: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1282: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1283: 
1.230     brouard  1284: int *Tvarsel; /**< Selected covariates for output */
                   1285: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1286: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1287: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1288: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1289: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1290: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1291: int *Tage;
1.227     brouard  1292: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1293: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1294: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1295: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1296: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1297: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1298: int **Tvard;
                   1299: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1300: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1301: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1302:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1303:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1304: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1305: double *lsurv, *lpop, *tpop;
                   1306: 
1.231     brouard  1307: #define FD 1; /* Fixed dummy covariate */
                   1308: #define FQ 2; /* Fixed quantitative covariate */
                   1309: #define FP 3; /* Fixed product covariate */
                   1310: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1311: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1312: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1313: #define VD 10; /* Varying dummy covariate */
                   1314: #define VQ 11; /* Varying quantitative covariate */
                   1315: #define VP 12; /* Varying product covariate */
                   1316: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1317: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1318: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1319: #define APFD 16; /* Age product * fixed dummy covariate */
                   1320: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1321: #define APVD 18; /* Age product * varying dummy covariate */
                   1322: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1323: 
                   1324: #define FTYPE 1; /* Fixed covariate */
                   1325: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1326: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1327: 
                   1328: struct kmodel{
                   1329:        int maintype; /* main type */
                   1330:        int subtype; /* subtype */
                   1331: };
                   1332: struct kmodel modell[NCOVMAX];
                   1333: 
1.143     brouard  1334: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1335: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1336: 
                   1337: /**************** split *************************/
                   1338: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1339: {
                   1340:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1341:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1342:   */ 
                   1343:   char *ss;                            /* pointer */
1.186     brouard  1344:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1345: 
                   1346:   l1 = strlen(path );                  /* length of path */
                   1347:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1348:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1349:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1350:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1351:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1352:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1353:     /* get current working directory */
                   1354:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1355: #ifdef WIN32
                   1356:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1357: #else
                   1358:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1359: #endif
1.126     brouard  1360:       return( GLOCK_ERROR_GETCWD );
                   1361:     }
                   1362:     /* got dirc from getcwd*/
                   1363:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1364:   } else {                             /* strip directory from path */
1.126     brouard  1365:     ss++;                              /* after this, the filename */
                   1366:     l2 = strlen( ss );                 /* length of filename */
                   1367:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1368:     strcpy( name, ss );                /* save file name */
                   1369:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1370:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1371:     printf(" DIRC2 = %s \n",dirc);
                   1372:   }
                   1373:   /* We add a separator at the end of dirc if not exists */
                   1374:   l1 = strlen( dirc );                 /* length of directory */
                   1375:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1376:     dirc[l1] =  DIRSEPARATOR;
                   1377:     dirc[l1+1] = 0; 
                   1378:     printf(" DIRC3 = %s \n",dirc);
                   1379:   }
                   1380:   ss = strrchr( name, '.' );           /* find last / */
                   1381:   if (ss >0){
                   1382:     ss++;
                   1383:     strcpy(ext,ss);                    /* save extension */
                   1384:     l1= strlen( name);
                   1385:     l2= strlen(ss)+1;
                   1386:     strncpy( finame, name, l1-l2);
                   1387:     finame[l1-l2]= 0;
                   1388:   }
                   1389: 
                   1390:   return( 0 );                         /* we're done */
                   1391: }
                   1392: 
                   1393: 
                   1394: /******************************************/
                   1395: 
                   1396: void replace_back_to_slash(char *s, char*t)
                   1397: {
                   1398:   int i;
                   1399:   int lg=0;
                   1400:   i=0;
                   1401:   lg=strlen(t);
                   1402:   for(i=0; i<= lg; i++) {
                   1403:     (s[i] = t[i]);
                   1404:     if (t[i]== '\\') s[i]='/';
                   1405:   }
                   1406: }
                   1407: 
1.132     brouard  1408: char *trimbb(char *out, char *in)
1.137     brouard  1409: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1410:   char *s;
                   1411:   s=out;
                   1412:   while (*in != '\0'){
1.137     brouard  1413:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1414:       in++;
                   1415:     }
                   1416:     *out++ = *in++;
                   1417:   }
                   1418:   *out='\0';
                   1419:   return s;
                   1420: }
                   1421: 
1.187     brouard  1422: /* char *substrchaine(char *out, char *in, char *chain) */
                   1423: /* { */
                   1424: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1425: /*   char *s, *t; */
                   1426: /*   t=in;s=out; */
                   1427: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1428: /*     *out++ = *in++; */
                   1429: /*   } */
                   1430: 
                   1431: /*   /\* *in matches *chain *\/ */
                   1432: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1433: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1434: /*   } */
                   1435: /*   in--; chain--; */
                   1436: /*   while ( (*in != '\0')){ */
                   1437: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1438: /*     *out++ = *in++; */
                   1439: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1440: /*   } */
                   1441: /*   *out='\0'; */
                   1442: /*   out=s; */
                   1443: /*   return out; */
                   1444: /* } */
                   1445: char *substrchaine(char *out, char *in, char *chain)
                   1446: {
                   1447:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1448:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1449: 
                   1450:   char *strloc;
                   1451: 
                   1452:   strcpy (out, in); 
                   1453:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1454:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1455:   if(strloc != NULL){ 
                   1456:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1457:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1458:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1459:   }
                   1460:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1461:   return out;
                   1462: }
                   1463: 
                   1464: 
1.145     brouard  1465: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1466: {
1.187     brouard  1467:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1468:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1469:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1470:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1471:   */
1.160     brouard  1472:   char *s, *t;
1.145     brouard  1473:   t=in;s=in;
                   1474:   while ((*in != occ) && (*in != '\0')){
                   1475:     *alocc++ = *in++;
                   1476:   }
                   1477:   if( *in == occ){
                   1478:     *(alocc)='\0';
                   1479:     s=++in;
                   1480:   }
                   1481:  
                   1482:   if (s == t) {/* occ not found */
                   1483:     *(alocc-(in-s))='\0';
                   1484:     in=s;
                   1485:   }
                   1486:   while ( *in != '\0'){
                   1487:     *blocc++ = *in++;
                   1488:   }
                   1489: 
                   1490:   *blocc='\0';
                   1491:   return t;
                   1492: }
1.137     brouard  1493: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1494: {
1.187     brouard  1495:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1496:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1497:      gives blocc="abcdef2ghi" and alocc="j".
                   1498:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1499:   */
                   1500:   char *s, *t;
                   1501:   t=in;s=in;
                   1502:   while (*in != '\0'){
                   1503:     while( *in == occ){
                   1504:       *blocc++ = *in++;
                   1505:       s=in;
                   1506:     }
                   1507:     *blocc++ = *in++;
                   1508:   }
                   1509:   if (s == t) /* occ not found */
                   1510:     *(blocc-(in-s))='\0';
                   1511:   else
                   1512:     *(blocc-(in-s)-1)='\0';
                   1513:   in=s;
                   1514:   while ( *in != '\0'){
                   1515:     *alocc++ = *in++;
                   1516:   }
                   1517: 
                   1518:   *alocc='\0';
                   1519:   return s;
                   1520: }
                   1521: 
1.126     brouard  1522: int nbocc(char *s, char occ)
                   1523: {
                   1524:   int i,j=0;
                   1525:   int lg=20;
                   1526:   i=0;
                   1527:   lg=strlen(s);
                   1528:   for(i=0; i<= lg; i++) {
1.234     brouard  1529:     if  (s[i] == occ ) j++;
1.126     brouard  1530:   }
                   1531:   return j;
                   1532: }
                   1533: 
1.137     brouard  1534: /* void cutv(char *u,char *v, char*t, char occ) */
                   1535: /* { */
                   1536: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1537: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1538: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1539: /*   int i,lg,j,p=0; */
                   1540: /*   i=0; */
                   1541: /*   lg=strlen(t); */
                   1542: /*   for(j=0; j<=lg-1; j++) { */
                   1543: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1544: /*   } */
1.126     brouard  1545: 
1.137     brouard  1546: /*   for(j=0; j<p; j++) { */
                   1547: /*     (u[j] = t[j]); */
                   1548: /*   } */
                   1549: /*      u[p]='\0'; */
1.126     brouard  1550: 
1.137     brouard  1551: /*    for(j=0; j<= lg; j++) { */
                   1552: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1553: /*   } */
                   1554: /* } */
1.126     brouard  1555: 
1.160     brouard  1556: #ifdef _WIN32
                   1557: char * strsep(char **pp, const char *delim)
                   1558: {
                   1559:   char *p, *q;
                   1560:          
                   1561:   if ((p = *pp) == NULL)
                   1562:     return 0;
                   1563:   if ((q = strpbrk (p, delim)) != NULL)
                   1564:   {
                   1565:     *pp = q + 1;
                   1566:     *q = '\0';
                   1567:   }
                   1568:   else
                   1569:     *pp = 0;
                   1570:   return p;
                   1571: }
                   1572: #endif
                   1573: 
1.126     brouard  1574: /********************** nrerror ********************/
                   1575: 
                   1576: void nrerror(char error_text[])
                   1577: {
                   1578:   fprintf(stderr,"ERREUR ...\n");
                   1579:   fprintf(stderr,"%s\n",error_text);
                   1580:   exit(EXIT_FAILURE);
                   1581: }
                   1582: /*********************** vector *******************/
                   1583: double *vector(int nl, int nh)
                   1584: {
                   1585:   double *v;
                   1586:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1587:   if (!v) nrerror("allocation failure in vector");
                   1588:   return v-nl+NR_END;
                   1589: }
                   1590: 
                   1591: /************************ free vector ******************/
                   1592: void free_vector(double*v, int nl, int nh)
                   1593: {
                   1594:   free((FREE_ARG)(v+nl-NR_END));
                   1595: }
                   1596: 
                   1597: /************************ivector *******************************/
                   1598: int *ivector(long nl,long nh)
                   1599: {
                   1600:   int *v;
                   1601:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1602:   if (!v) nrerror("allocation failure in ivector");
                   1603:   return v-nl+NR_END;
                   1604: }
                   1605: 
                   1606: /******************free ivector **************************/
                   1607: void free_ivector(int *v, long nl, long nh)
                   1608: {
                   1609:   free((FREE_ARG)(v+nl-NR_END));
                   1610: }
                   1611: 
                   1612: /************************lvector *******************************/
                   1613: long *lvector(long nl,long nh)
                   1614: {
                   1615:   long *v;
                   1616:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1617:   if (!v) nrerror("allocation failure in ivector");
                   1618:   return v-nl+NR_END;
                   1619: }
                   1620: 
                   1621: /******************free lvector **************************/
                   1622: void free_lvector(long *v, long nl, long nh)
                   1623: {
                   1624:   free((FREE_ARG)(v+nl-NR_END));
                   1625: }
                   1626: 
                   1627: /******************* imatrix *******************************/
                   1628: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1629:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1630: { 
                   1631:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1632:   int **m; 
                   1633:   
                   1634:   /* allocate pointers to rows */ 
                   1635:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1636:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1637:   m += NR_END; 
                   1638:   m -= nrl; 
                   1639:   
                   1640:   
                   1641:   /* allocate rows and set pointers to them */ 
                   1642:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1643:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1644:   m[nrl] += NR_END; 
                   1645:   m[nrl] -= ncl; 
                   1646:   
                   1647:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1648:   
                   1649:   /* return pointer to array of pointers to rows */ 
                   1650:   return m; 
                   1651: } 
                   1652: 
                   1653: /****************** free_imatrix *************************/
                   1654: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1655:       int **m;
                   1656:       long nch,ncl,nrh,nrl; 
                   1657:      /* free an int matrix allocated by imatrix() */ 
                   1658: { 
                   1659:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1660:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1661: } 
                   1662: 
                   1663: /******************* matrix *******************************/
                   1664: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1665: {
                   1666:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1667:   double **m;
                   1668: 
                   1669:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1670:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1671:   m += NR_END;
                   1672:   m -= nrl;
                   1673: 
                   1674:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1675:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1676:   m[nrl] += NR_END;
                   1677:   m[nrl] -= ncl;
                   1678: 
                   1679:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1680:   return m;
1.145     brouard  1681:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1682: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1683: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1684:    */
                   1685: }
                   1686: 
                   1687: /*************************free matrix ************************/
                   1688: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1689: {
                   1690:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1691:   free((FREE_ARG)(m+nrl-NR_END));
                   1692: }
                   1693: 
                   1694: /******************* ma3x *******************************/
                   1695: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1696: {
                   1697:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1698:   double ***m;
                   1699: 
                   1700:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1701:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1702:   m += NR_END;
                   1703:   m -= nrl;
                   1704: 
                   1705:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1706:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1707:   m[nrl] += NR_END;
                   1708:   m[nrl] -= ncl;
                   1709: 
                   1710:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1711: 
                   1712:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1713:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1714:   m[nrl][ncl] += NR_END;
                   1715:   m[nrl][ncl] -= nll;
                   1716:   for (j=ncl+1; j<=nch; j++) 
                   1717:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1718:   
                   1719:   for (i=nrl+1; i<=nrh; i++) {
                   1720:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1721:     for (j=ncl+1; j<=nch; j++) 
                   1722:       m[i][j]=m[i][j-1]+nlay;
                   1723:   }
                   1724:   return m; 
                   1725:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1726:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1727:   */
                   1728: }
                   1729: 
                   1730: /*************************free ma3x ************************/
                   1731: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1732: {
                   1733:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1734:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1735:   free((FREE_ARG)(m+nrl-NR_END));
                   1736: }
                   1737: 
                   1738: /*************** function subdirf ***********/
                   1739: char *subdirf(char fileres[])
                   1740: {
                   1741:   /* Caution optionfilefiname is hidden */
                   1742:   strcpy(tmpout,optionfilefiname);
                   1743:   strcat(tmpout,"/"); /* Add to the right */
                   1744:   strcat(tmpout,fileres);
                   1745:   return tmpout;
                   1746: }
                   1747: 
                   1748: /*************** function subdirf2 ***********/
                   1749: char *subdirf2(char fileres[], char *preop)
                   1750: {
                   1751:   
                   1752:   /* Caution optionfilefiname is hidden */
                   1753:   strcpy(tmpout,optionfilefiname);
                   1754:   strcat(tmpout,"/");
                   1755:   strcat(tmpout,preop);
                   1756:   strcat(tmpout,fileres);
                   1757:   return tmpout;
                   1758: }
                   1759: 
                   1760: /*************** function subdirf3 ***********/
                   1761: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1762: {
                   1763:   
                   1764:   /* Caution optionfilefiname is hidden */
                   1765:   strcpy(tmpout,optionfilefiname);
                   1766:   strcat(tmpout,"/");
                   1767:   strcat(tmpout,preop);
                   1768:   strcat(tmpout,preop2);
                   1769:   strcat(tmpout,fileres);
                   1770:   return tmpout;
                   1771: }
1.213     brouard  1772:  
                   1773: /*************** function subdirfext ***********/
                   1774: char *subdirfext(char fileres[], char *preop, char *postop)
                   1775: {
                   1776:   
                   1777:   strcpy(tmpout,preop);
                   1778:   strcat(tmpout,fileres);
                   1779:   strcat(tmpout,postop);
                   1780:   return tmpout;
                   1781: }
1.126     brouard  1782: 
1.213     brouard  1783: /*************** function subdirfext3 ***********/
                   1784: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1785: {
                   1786:   
                   1787:   /* Caution optionfilefiname is hidden */
                   1788:   strcpy(tmpout,optionfilefiname);
                   1789:   strcat(tmpout,"/");
                   1790:   strcat(tmpout,preop);
                   1791:   strcat(tmpout,fileres);
                   1792:   strcat(tmpout,postop);
                   1793:   return tmpout;
                   1794: }
                   1795:  
1.162     brouard  1796: char *asc_diff_time(long time_sec, char ascdiff[])
                   1797: {
                   1798:   long sec_left, days, hours, minutes;
                   1799:   days = (time_sec) / (60*60*24);
                   1800:   sec_left = (time_sec) % (60*60*24);
                   1801:   hours = (sec_left) / (60*60) ;
                   1802:   sec_left = (sec_left) %(60*60);
                   1803:   minutes = (sec_left) /60;
                   1804:   sec_left = (sec_left) % (60);
                   1805:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1806:   return ascdiff;
                   1807: }
                   1808: 
1.126     brouard  1809: /***************** f1dim *************************/
                   1810: extern int ncom; 
                   1811: extern double *pcom,*xicom;
                   1812: extern double (*nrfunc)(double []); 
                   1813:  
                   1814: double f1dim(double x) 
                   1815: { 
                   1816:   int j; 
                   1817:   double f;
                   1818:   double *xt; 
                   1819:  
                   1820:   xt=vector(1,ncom); 
                   1821:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1822:   f=(*nrfunc)(xt); 
                   1823:   free_vector(xt,1,ncom); 
                   1824:   return f; 
                   1825: } 
                   1826: 
                   1827: /*****************brent *************************/
                   1828: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1829: {
                   1830:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1831:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1832:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1833:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1834:    * returned function value. 
                   1835:   */
1.126     brouard  1836:   int iter; 
                   1837:   double a,b,d,etemp;
1.159     brouard  1838:   double fu=0,fv,fw,fx;
1.164     brouard  1839:   double ftemp=0.;
1.126     brouard  1840:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1841:   double e=0.0; 
                   1842:  
                   1843:   a=(ax < cx ? ax : cx); 
                   1844:   b=(ax > cx ? ax : cx); 
                   1845:   x=w=v=bx; 
                   1846:   fw=fv=fx=(*f)(x); 
                   1847:   for (iter=1;iter<=ITMAX;iter++) { 
                   1848:     xm=0.5*(a+b); 
                   1849:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1850:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1851:     printf(".");fflush(stdout);
                   1852:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1853: #ifdef DEBUGBRENT
1.126     brouard  1854:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1855:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1856:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1857: #endif
                   1858:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1859:       *xmin=x; 
                   1860:       return fx; 
                   1861:     } 
                   1862:     ftemp=fu;
                   1863:     if (fabs(e) > tol1) { 
                   1864:       r=(x-w)*(fx-fv); 
                   1865:       q=(x-v)*(fx-fw); 
                   1866:       p=(x-v)*q-(x-w)*r; 
                   1867:       q=2.0*(q-r); 
                   1868:       if (q > 0.0) p = -p; 
                   1869:       q=fabs(q); 
                   1870:       etemp=e; 
                   1871:       e=d; 
                   1872:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1873:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1874:       else { 
1.224     brouard  1875:                                d=p/q; 
                   1876:                                u=x+d; 
                   1877:                                if (u-a < tol2 || b-u < tol2) 
                   1878:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1879:       } 
                   1880:     } else { 
                   1881:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1882:     } 
                   1883:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1884:     fu=(*f)(u); 
                   1885:     if (fu <= fx) { 
                   1886:       if (u >= x) a=x; else b=x; 
                   1887:       SHFT(v,w,x,u) 
1.183     brouard  1888:       SHFT(fv,fw,fx,fu) 
                   1889:     } else { 
                   1890:       if (u < x) a=u; else b=u; 
                   1891:       if (fu <= fw || w == x) { 
1.224     brouard  1892:                                v=w; 
                   1893:                                w=u; 
                   1894:                                fv=fw; 
                   1895:                                fw=fu; 
1.183     brouard  1896:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1897:                                v=u; 
                   1898:                                fv=fu; 
1.183     brouard  1899:       } 
                   1900:     } 
1.126     brouard  1901:   } 
                   1902:   nrerror("Too many iterations in brent"); 
                   1903:   *xmin=x; 
                   1904:   return fx; 
                   1905: } 
                   1906: 
                   1907: /****************** mnbrak ***********************/
                   1908: 
                   1909: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1910:            double (*func)(double)) 
1.183     brouard  1911: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1912: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1913: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1914: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1915:    */
1.126     brouard  1916:   double ulim,u,r,q, dum;
                   1917:   double fu; 
1.187     brouard  1918: 
                   1919:   double scale=10.;
                   1920:   int iterscale=0;
                   1921: 
                   1922:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1923:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1924: 
                   1925: 
                   1926:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1927:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1928:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1929:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1930:   /* } */
                   1931: 
1.126     brouard  1932:   if (*fb > *fa) { 
                   1933:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1934:     SHFT(dum,*fb,*fa,dum) 
                   1935:   } 
1.126     brouard  1936:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1937:   *fc=(*func)(*cx); 
1.183     brouard  1938: #ifdef DEBUG
1.224     brouard  1939:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1940:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1941: #endif
1.224     brouard  1942:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1943:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1944:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1945:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1946:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1947:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1948:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1949:       fu=(*func)(u); 
1.163     brouard  1950: #ifdef DEBUG
                   1951:       /* f(x)=A(x-u)**2+f(u) */
                   1952:       double A, fparabu; 
                   1953:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1954:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1955:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1956:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1957:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1958:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1959:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1960:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1961: #endif 
1.184     brouard  1962: #ifdef MNBRAKORIGINAL
1.183     brouard  1963: #else
1.191     brouard  1964: /*       if (fu > *fc) { */
                   1965: /* #ifdef DEBUG */
                   1966: /*       printf("mnbrak4  fu > fc \n"); */
                   1967: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1968: /* #endif */
                   1969: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1970: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1971: /*     dum=u; /\* Shifting c and u *\/ */
                   1972: /*     u = *cx; */
                   1973: /*     *cx = dum; */
                   1974: /*     dum = fu; */
                   1975: /*     fu = *fc; */
                   1976: /*     *fc =dum; */
                   1977: /*       } else { /\* end *\/ */
                   1978: /* #ifdef DEBUG */
                   1979: /*       printf("mnbrak3  fu < fc \n"); */
                   1980: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1981: /* #endif */
                   1982: /*     dum=u; /\* Shifting c and u *\/ */
                   1983: /*     u = *cx; */
                   1984: /*     *cx = dum; */
                   1985: /*     dum = fu; */
                   1986: /*     fu = *fc; */
                   1987: /*     *fc =dum; */
                   1988: /*       } */
1.224     brouard  1989: #ifdef DEBUGMNBRAK
                   1990:                 double A, fparabu; 
                   1991:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1992:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1993:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1994:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1995: #endif
1.191     brouard  1996:       dum=u; /* Shifting c and u */
                   1997:       u = *cx;
                   1998:       *cx = dum;
                   1999:       dum = fu;
                   2000:       fu = *fc;
                   2001:       *fc =dum;
1.183     brouard  2002: #endif
1.162     brouard  2003:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2004: #ifdef DEBUG
1.224     brouard  2005:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2006:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2007: #endif
1.126     brouard  2008:       fu=(*func)(u); 
                   2009:       if (fu < *fc) { 
1.183     brouard  2010: #ifdef DEBUG
1.224     brouard  2011:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2012:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2013: #endif
                   2014:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2015:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2016: #ifdef DEBUG
                   2017:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2018: #endif
                   2019:       } 
1.162     brouard  2020:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2021: #ifdef DEBUG
1.224     brouard  2022:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2023:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2024: #endif
1.126     brouard  2025:       u=ulim; 
                   2026:       fu=(*func)(u); 
1.183     brouard  2027:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2028: #ifdef DEBUG
1.224     brouard  2029:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2030:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2031: #endif
1.126     brouard  2032:       u=(*cx)+GOLD*(*cx-*bx); 
                   2033:       fu=(*func)(u); 
1.224     brouard  2034: #ifdef DEBUG
                   2035:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2036:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2037: #endif
1.183     brouard  2038:     } /* end tests */
1.126     brouard  2039:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2040:     SHFT(*fa,*fb,*fc,fu) 
                   2041: #ifdef DEBUG
1.224     brouard  2042:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2043:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2044: #endif
                   2045:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2046: } 
                   2047: 
                   2048: /*************** linmin ************************/
1.162     brouard  2049: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2050: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2051: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2052: the value of func at the returned location p . This is actually all accomplished by calling the
                   2053: routines mnbrak and brent .*/
1.126     brouard  2054: int ncom; 
                   2055: double *pcom,*xicom;
                   2056: double (*nrfunc)(double []); 
                   2057:  
1.224     brouard  2058: #ifdef LINMINORIGINAL
1.126     brouard  2059: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2060: #else
                   2061: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2062: #endif
1.126     brouard  2063: { 
                   2064:   double brent(double ax, double bx, double cx, 
                   2065:               double (*f)(double), double tol, double *xmin); 
                   2066:   double f1dim(double x); 
                   2067:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2068:              double *fc, double (*func)(double)); 
                   2069:   int j; 
                   2070:   double xx,xmin,bx,ax; 
                   2071:   double fx,fb,fa;
1.187     brouard  2072: 
1.203     brouard  2073: #ifdef LINMINORIGINAL
                   2074: #else
                   2075:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2076: #endif
                   2077:   
1.126     brouard  2078:   ncom=n; 
                   2079:   pcom=vector(1,n); 
                   2080:   xicom=vector(1,n); 
                   2081:   nrfunc=func; 
                   2082:   for (j=1;j<=n;j++) { 
                   2083:     pcom[j]=p[j]; 
1.202     brouard  2084:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2085:   } 
1.187     brouard  2086: 
1.203     brouard  2087: #ifdef LINMINORIGINAL
                   2088:   xx=1.;
                   2089: #else
                   2090:   axs=0.0;
                   2091:   xxs=1.;
                   2092:   do{
                   2093:     xx= xxs;
                   2094: #endif
1.187     brouard  2095:     ax=0.;
                   2096:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2097:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2098:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2099:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2100:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2101:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2102:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2103: #ifdef LINMINORIGINAL
                   2104: #else
                   2105:     if (fx != fx){
1.224     brouard  2106:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2107:                        printf("|");
                   2108:                        fprintf(ficlog,"|");
1.203     brouard  2109: #ifdef DEBUGLINMIN
1.224     brouard  2110:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2111: #endif
                   2112:     }
1.224     brouard  2113:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2114: #endif
                   2115:   
1.191     brouard  2116: #ifdef DEBUGLINMIN
                   2117:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2118:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2119: #endif
1.224     brouard  2120: #ifdef LINMINORIGINAL
                   2121: #else
                   2122:        if(fb == fx){ /* Flat function in the direction */
                   2123:                xmin=xx;
                   2124:     *flat=1;
                   2125:        }else{
                   2126:     *flat=0;
                   2127: #endif
                   2128:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2129:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2130:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2131:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2132:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2133:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2134: #ifdef DEBUG
1.224     brouard  2135:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2136:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2137: #endif
                   2138: #ifdef LINMINORIGINAL
                   2139: #else
                   2140:                        }
1.126     brouard  2141: #endif
1.191     brouard  2142: #ifdef DEBUGLINMIN
                   2143:   printf("linmin end ");
1.202     brouard  2144:   fprintf(ficlog,"linmin end ");
1.191     brouard  2145: #endif
1.126     brouard  2146:   for (j=1;j<=n;j++) { 
1.203     brouard  2147: #ifdef LINMINORIGINAL
                   2148:     xi[j] *= xmin; 
                   2149: #else
                   2150: #ifdef DEBUGLINMIN
                   2151:     if(xxs <1.0)
                   2152:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2153: #endif
                   2154:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2155: #ifdef DEBUGLINMIN
                   2156:     if(xxs <1.0)
                   2157:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2158: #endif
                   2159: #endif
1.187     brouard  2160:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2161:   } 
1.191     brouard  2162: #ifdef DEBUGLINMIN
1.203     brouard  2163:   printf("\n");
1.191     brouard  2164:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2165:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2166:   for (j=1;j<=n;j++) { 
1.202     brouard  2167:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2168:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2169:     if(j % ncovmodel == 0){
1.191     brouard  2170:       printf("\n");
1.202     brouard  2171:       fprintf(ficlog,"\n");
                   2172:     }
1.191     brouard  2173:   }
1.203     brouard  2174: #else
1.191     brouard  2175: #endif
1.126     brouard  2176:   free_vector(xicom,1,n); 
                   2177:   free_vector(pcom,1,n); 
                   2178: } 
                   2179: 
                   2180: 
                   2181: /*************** powell ************************/
1.162     brouard  2182: /*
                   2183: Minimization of a function func of n variables. Input consists of an initial starting point
                   2184: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2185: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2186: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2187: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2188: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2189:  */
1.224     brouard  2190: #ifdef LINMINORIGINAL
                   2191: #else
                   2192:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2193:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2194: #endif
1.126     brouard  2195: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2196:            double (*func)(double [])) 
                   2197: { 
1.224     brouard  2198: #ifdef LINMINORIGINAL
                   2199:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2200:              double (*func)(double [])); 
1.224     brouard  2201: #else 
1.241     brouard  2202:  void linmin(double p[], double xi[], int n, double *fret,
                   2203:             double (*func)(double []),int *flat); 
1.224     brouard  2204: #endif
1.239     brouard  2205:  int i,ibig,j,jk,k; 
1.126     brouard  2206:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2207:   double directest;
1.126     brouard  2208:   double fp,fptt;
                   2209:   double *xits;
                   2210:   int niterf, itmp;
1.224     brouard  2211: #ifdef LINMINORIGINAL
                   2212: #else
                   2213: 
                   2214:   flatdir=ivector(1,n); 
                   2215:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2216: #endif
1.126     brouard  2217: 
                   2218:   pt=vector(1,n); 
                   2219:   ptt=vector(1,n); 
                   2220:   xit=vector(1,n); 
                   2221:   xits=vector(1,n); 
                   2222:   *fret=(*func)(p); 
                   2223:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2224:   rcurr_time = time(NULL);  
1.126     brouard  2225:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2226:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2227:     ibig=0; 
                   2228:     del=0.0; 
1.157     brouard  2229:     rlast_time=rcurr_time;
                   2230:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2231:     rcurr_time = time(NULL);  
                   2232:     curr_time = *localtime(&rcurr_time);
                   2233:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2234:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2235: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2236:     for (i=1;i<=n;i++) {
1.126     brouard  2237:       fprintf(ficrespow," %.12lf", p[i]);
                   2238:     }
1.239     brouard  2239:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2240:     printf("\n#model=  1      +     age ");
                   2241:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2242:     if(nagesqr==1){
1.241     brouard  2243:        printf("  + age*age  ");
                   2244:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2245:     }
                   2246:     for(j=1;j <=ncovmodel-2;j++){
                   2247:       if(Typevar[j]==0) {
                   2248:        printf("  +      V%d  ",Tvar[j]);
                   2249:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2250:       }else if(Typevar[j]==1) {
                   2251:        printf("  +    V%d*age ",Tvar[j]);
                   2252:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2253:       }else if(Typevar[j]==2) {
                   2254:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2255:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2256:       }
                   2257:     }
1.126     brouard  2258:     printf("\n");
1.239     brouard  2259: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2260: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2261:     fprintf(ficlog,"\n");
1.239     brouard  2262:     for(i=1,jk=1; i <=nlstate; i++){
                   2263:       for(k=1; k <=(nlstate+ndeath); k++){
                   2264:        if (k != i) {
                   2265:          printf("%d%d ",i,k);
                   2266:          fprintf(ficlog,"%d%d ",i,k);
                   2267:          for(j=1; j <=ncovmodel; j++){
                   2268:            printf("%12.7f ",p[jk]);
                   2269:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2270:            jk++; 
                   2271:          }
                   2272:          printf("\n");
                   2273:          fprintf(ficlog,"\n");
                   2274:        }
                   2275:       }
                   2276:     }
1.241     brouard  2277:     if(*iter <=3 && *iter >1){
1.157     brouard  2278:       tml = *localtime(&rcurr_time);
                   2279:       strcpy(strcurr,asctime(&tml));
                   2280:       rforecast_time=rcurr_time; 
1.126     brouard  2281:       itmp = strlen(strcurr);
                   2282:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2283:        strcurr[itmp-1]='\0';
1.162     brouard  2284:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2285:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2286:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2287:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2288:        forecast_time = *localtime(&rforecast_time);
                   2289:        strcpy(strfor,asctime(&forecast_time));
                   2290:        itmp = strlen(strfor);
                   2291:        if(strfor[itmp-1]=='\n')
                   2292:          strfor[itmp-1]='\0';
                   2293:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2294:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2295:       }
                   2296:     }
1.187     brouard  2297:     for (i=1;i<=n;i++) { /* For each direction i */
                   2298:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2299:       fptt=(*fret); 
                   2300: #ifdef DEBUG
1.203     brouard  2301:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2302:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2303: #endif
1.203     brouard  2304:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2305:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2306: #ifdef LINMINORIGINAL
1.188     brouard  2307:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2308: #else
                   2309:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2310:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2311: #endif
                   2312:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2313:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2314:                                /* because that direction will be replaced unless the gain del is small */
                   2315:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2316:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2317:                                /* with the new direction. */
                   2318:                                del=fabs(fptt-(*fret)); 
                   2319:                                ibig=i; 
1.126     brouard  2320:       } 
                   2321: #ifdef DEBUG
                   2322:       printf("%d %.12e",i,(*fret));
                   2323:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2324:       for (j=1;j<=n;j++) {
1.224     brouard  2325:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2326:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2327:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2328:       }
                   2329:       for(j=1;j<=n;j++) {
1.225     brouard  2330:                                printf(" p(%d)=%.12e",j,p[j]);
                   2331:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2332:       }
                   2333:       printf("\n");
                   2334:       fprintf(ficlog,"\n");
                   2335: #endif
1.187     brouard  2336:     } /* end loop on each direction i */
                   2337:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2338:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2339:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2340:       for(j=1;j<=n;j++) {
1.225     brouard  2341:                                if(flatdir[j] >0){
                   2342:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2343:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2344:                                }
                   2345:                                /* printf("\n"); */
                   2346:                                /* fprintf(ficlog,"\n"); */
                   2347:                        }
1.243     brouard  2348:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2349:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2350:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2351:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2352:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2353:       /* decreased of more than 3.84  */
                   2354:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2355:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2356:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2357:                        
1.188     brouard  2358:       /* Starting the program with initial values given by a former maximization will simply change */
                   2359:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2360:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2361:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2362: #ifdef DEBUG
                   2363:       int k[2],l;
                   2364:       k[0]=1;
                   2365:       k[1]=-1;
                   2366:       printf("Max: %.12e",(*func)(p));
                   2367:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2368:       for (j=1;j<=n;j++) {
                   2369:        printf(" %.12e",p[j]);
                   2370:        fprintf(ficlog," %.12e",p[j]);
                   2371:       }
                   2372:       printf("\n");
                   2373:       fprintf(ficlog,"\n");
                   2374:       for(l=0;l<=1;l++) {
                   2375:        for (j=1;j<=n;j++) {
                   2376:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2377:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2378:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2379:        }
                   2380:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2381:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2382:       }
                   2383: #endif
                   2384: 
1.224     brouard  2385: #ifdef LINMINORIGINAL
                   2386: #else
                   2387:       free_ivector(flatdir,1,n); 
                   2388: #endif
1.126     brouard  2389:       free_vector(xit,1,n); 
                   2390:       free_vector(xits,1,n); 
                   2391:       free_vector(ptt,1,n); 
                   2392:       free_vector(pt,1,n); 
                   2393:       return; 
1.192     brouard  2394:     } /* enough precision */ 
1.240     brouard  2395:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2396:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2397:       ptt[j]=2.0*p[j]-pt[j]; 
                   2398:       xit[j]=p[j]-pt[j]; 
                   2399:       pt[j]=p[j]; 
                   2400:     } 
1.181     brouard  2401:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2402: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2403:                if (*iter <=4) {
1.225     brouard  2404: #else
                   2405: #endif
1.224     brouard  2406: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2407: #else
1.161     brouard  2408:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2409: #endif
1.162     brouard  2410:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2411:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2412:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2413:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2414:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2415:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2416:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2417:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2418:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2419:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2420:       /* mu² and del² are equal when f3=f1 */
                   2421:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2422:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2423:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2424:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2425: #ifdef NRCORIGINAL
                   2426:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2427: #else
                   2428:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2429:       t= t- del*SQR(fp-fptt);
1.183     brouard  2430: #endif
1.202     brouard  2431:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2432: #ifdef DEBUG
1.181     brouard  2433:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2434:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2435:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2436:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2437:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2438:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2439:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2440:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2441: #endif
1.183     brouard  2442: #ifdef POWELLORIGINAL
                   2443:       if (t < 0.0) { /* Then we use it for new direction */
                   2444: #else
1.182     brouard  2445:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2446:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2447:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2448:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2449:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2450:       } 
1.181     brouard  2451:       if (directest < 0.0) { /* Then we use it for new direction */
                   2452: #endif
1.191     brouard  2453: #ifdef DEBUGLINMIN
1.234     brouard  2454:        printf("Before linmin in direction P%d-P0\n",n);
                   2455:        for (j=1;j<=n;j++) {
                   2456:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2457:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2458:          if(j % ncovmodel == 0){
                   2459:            printf("\n");
                   2460:            fprintf(ficlog,"\n");
                   2461:          }
                   2462:        }
1.224     brouard  2463: #endif
                   2464: #ifdef LINMINORIGINAL
1.234     brouard  2465:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2466: #else
1.234     brouard  2467:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2468:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2469: #endif
1.234     brouard  2470:        
1.191     brouard  2471: #ifdef DEBUGLINMIN
1.234     brouard  2472:        for (j=1;j<=n;j++) { 
                   2473:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2474:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2475:          if(j % ncovmodel == 0){
                   2476:            printf("\n");
                   2477:            fprintf(ficlog,"\n");
                   2478:          }
                   2479:        }
1.224     brouard  2480: #endif
1.234     brouard  2481:        for (j=1;j<=n;j++) { 
                   2482:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2483:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2484:        }
1.224     brouard  2485: #ifdef LINMINORIGINAL
                   2486: #else
1.234     brouard  2487:        for (j=1, flatd=0;j<=n;j++) {
                   2488:          if(flatdir[j]>0)
                   2489:            flatd++;
                   2490:        }
                   2491:        if(flatd >0){
1.255     brouard  2492:          printf("%d flat directions: ",flatd);
                   2493:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2494:          for (j=1;j<=n;j++) { 
                   2495:            if(flatdir[j]>0){
                   2496:              printf("%d ",j);
                   2497:              fprintf(ficlog,"%d ",j);
                   2498:            }
                   2499:          }
                   2500:          printf("\n");
                   2501:          fprintf(ficlog,"\n");
                   2502:        }
1.191     brouard  2503: #endif
1.234     brouard  2504:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2505:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2506:        
1.126     brouard  2507: #ifdef DEBUG
1.234     brouard  2508:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2509:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2510:        for(j=1;j<=n;j++){
                   2511:          printf(" %lf",xit[j]);
                   2512:          fprintf(ficlog," %lf",xit[j]);
                   2513:        }
                   2514:        printf("\n");
                   2515:        fprintf(ficlog,"\n");
1.126     brouard  2516: #endif
1.192     brouard  2517:       } /* end of t or directest negative */
1.224     brouard  2518: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2519: #else
1.234     brouard  2520:       } /* end if (fptt < fp)  */
1.192     brouard  2521: #endif
1.225     brouard  2522: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2523:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2524: #else
1.224     brouard  2525: #endif
1.234     brouard  2526:                } /* loop iteration */ 
1.126     brouard  2527: } 
1.234     brouard  2528:   
1.126     brouard  2529: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2530:   
1.235     brouard  2531:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2532:   {
1.279     brouard  2533:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2534:      *   (and selected quantitative values in nres)
                   2535:      *  by left multiplying the unit
                   2536:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2537:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2538:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2539:      * or prevalence in state 1, prevalence in state 2, 0
                   2540:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2541:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2542:      * Output is prlim.
                   2543:      * Initial matrix pimij 
                   2544:      */
1.206     brouard  2545:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2546:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2547:   /*  0,                   0                  , 1} */
                   2548:   /*
                   2549:    * and after some iteration: */
                   2550:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2551:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2552:   /*  0,                   0                  , 1} */
                   2553:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2554:   /* {0.51571254859325999, 0.4842874514067399, */
                   2555:   /*  0.51326036147820708, 0.48673963852179264} */
                   2556:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2557:     
1.126     brouard  2558:   int i, ii,j,k;
1.209     brouard  2559:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2560:   /* double **matprod2(); */ /* test */
1.218     brouard  2561:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2562:   double **newm;
1.209     brouard  2563:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2564:   int ncvloop=0;
1.169     brouard  2565:   
1.209     brouard  2566:   min=vector(1,nlstate);
                   2567:   max=vector(1,nlstate);
                   2568:   meandiff=vector(1,nlstate);
                   2569: 
1.218     brouard  2570:        /* Starting with matrix unity */
1.126     brouard  2571:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2572:     for (j=1;j<=nlstate+ndeath;j++){
                   2573:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2574:     }
1.169     brouard  2575:   
                   2576:   cov[1]=1.;
                   2577:   
                   2578:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2579:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2580:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2581:     ncvloop++;
1.126     brouard  2582:     newm=savm;
                   2583:     /* Covariates have to be included here again */
1.138     brouard  2584:     cov[2]=agefin;
1.187     brouard  2585:     if(nagesqr==1)
                   2586:       cov[3]= agefin*agefin;;
1.234     brouard  2587:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2588:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2589:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2590:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2591:     }
                   2592:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2593:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2594:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2595:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2596:     }
1.237     brouard  2597:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2598:       if(Dummy[Tvar[Tage[k]]]){
                   2599:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2600:       } else{
1.235     brouard  2601:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2602:       }
1.235     brouard  2603:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2604:     }
1.237     brouard  2605:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2606:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2607:       if(Dummy[Tvard[k][1]==0]){
                   2608:        if(Dummy[Tvard[k][2]==0]){
                   2609:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2610:        }else{
                   2611:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2612:        }
                   2613:       }else{
                   2614:        if(Dummy[Tvard[k][2]==0]){
                   2615:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2616:        }else{
                   2617:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2618:        }
                   2619:       }
1.234     brouard  2620:     }
1.138     brouard  2621:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2622:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2623:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2624:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2625:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2626:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2627:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2628:     
1.126     brouard  2629:     savm=oldm;
                   2630:     oldm=newm;
1.209     brouard  2631: 
                   2632:     for(j=1; j<=nlstate; j++){
                   2633:       max[j]=0.;
                   2634:       min[j]=1.;
                   2635:     }
                   2636:     for(i=1;i<=nlstate;i++){
                   2637:       sumnew=0;
                   2638:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2639:       for(j=1; j<=nlstate; j++){ 
                   2640:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2641:        max[j]=FMAX(max[j],prlim[i][j]);
                   2642:        min[j]=FMIN(min[j],prlim[i][j]);
                   2643:       }
                   2644:     }
                   2645: 
1.126     brouard  2646:     maxmax=0.;
1.209     brouard  2647:     for(j=1; j<=nlstate; j++){
                   2648:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2649:       maxmax=FMAX(maxmax,meandiff[j]);
                   2650:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2651:     } /* j loop */
1.203     brouard  2652:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2653:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2654:     if(maxmax < ftolpl){
1.209     brouard  2655:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2656:       free_vector(min,1,nlstate);
                   2657:       free_vector(max,1,nlstate);
                   2658:       free_vector(meandiff,1,nlstate);
1.126     brouard  2659:       return prlim;
                   2660:     }
1.169     brouard  2661:   } /* age loop */
1.208     brouard  2662:     /* After some age loop it doesn't converge */
1.209     brouard  2663:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2664: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2665:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2666:   free_vector(min,1,nlstate);
                   2667:   free_vector(max,1,nlstate);
                   2668:   free_vector(meandiff,1,nlstate);
1.208     brouard  2669:   
1.169     brouard  2670:   return prlim; /* should not reach here */
1.126     brouard  2671: }
                   2672: 
1.217     brouard  2673: 
                   2674:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2675: 
1.218     brouard  2676:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2677:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2678:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2679: {
1.264     brouard  2680:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2681:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2682:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2683:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2684:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2685:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2686:   /* Initial matrix pimij */
                   2687:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2688:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2689:   /*  0,                   0                  , 1} */
                   2690:   /*
                   2691:    * and after some iteration: */
                   2692:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2693:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2694:   /*  0,                   0                  , 1} */
                   2695:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2696:   /* {0.51571254859325999, 0.4842874514067399, */
                   2697:   /*  0.51326036147820708, 0.48673963852179264} */
                   2698:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2699: 
                   2700:   int i, ii,j,k;
1.247     brouard  2701:   int first=0;
1.217     brouard  2702:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2703:   /* double **matprod2(); */ /* test */
                   2704:   double **out, cov[NCOVMAX+1], **bmij();
                   2705:   double **newm;
1.218     brouard  2706:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2707:   double        **oldm, **savm;  /* for use */
                   2708: 
1.217     brouard  2709:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2710:   int ncvloop=0;
                   2711:   
                   2712:   min=vector(1,nlstate);
                   2713:   max=vector(1,nlstate);
                   2714:   meandiff=vector(1,nlstate);
                   2715: 
1.266     brouard  2716:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2717:   oldm=oldms; savm=savms;
                   2718:   
                   2719:   /* Starting with matrix unity */
                   2720:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2721:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2722:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2723:     }
                   2724:   
                   2725:   cov[1]=1.;
                   2726:   
                   2727:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2728:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2729:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2730:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2731:     ncvloop++;
1.218     brouard  2732:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2733:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2734:     /* Covariates have to be included here again */
                   2735:     cov[2]=agefin;
                   2736:     if(nagesqr==1)
                   2737:       cov[3]= agefin*agefin;;
1.242     brouard  2738:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2739:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2740:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2741:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2742:     }
                   2743:     /* for (k=1; k<=cptcovn;k++) { */
                   2744:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2745:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2746:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2747:     /* } */
                   2748:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2749:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2750:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2751:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2752:     }
                   2753:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2754:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2755:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2756:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2757:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2758:       if(Dummy[Tvar[Tage[k]]]){
                   2759:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2760:       } else{
                   2761:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2762:       }
                   2763:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2764:     }
                   2765:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2766:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2767:       if(Dummy[Tvard[k][1]==0]){
                   2768:        if(Dummy[Tvard[k][2]==0]){
                   2769:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2770:        }else{
                   2771:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2772:        }
                   2773:       }else{
                   2774:        if(Dummy[Tvard[k][2]==0]){
                   2775:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2776:        }else{
                   2777:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2778:        }
                   2779:       }
1.217     brouard  2780:     }
                   2781:     
                   2782:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2783:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2784:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2785:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2786:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2787:                /* ij should be linked to the correct index of cov */
                   2788:                /* age and covariate values ij are in 'cov', but we need to pass
                   2789:                 * ij for the observed prevalence at age and status and covariate
                   2790:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2791:                 */
                   2792:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2793:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2794:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2795:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2796:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2797:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2798:     /*         printf("%d newm= ",i); */
                   2799:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2800:     /*           printf("%f ",newm[i][j]); */
                   2801:     /*         } */
                   2802:     /*         printf("oldm * "); */
                   2803:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2804:     /*           printf("%f ",oldm[i][j]); */
                   2805:     /*         } */
1.268     brouard  2806:     /*         printf(" bmmij "); */
1.266     brouard  2807:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2808:     /*           printf("%f ",pmmij[i][j]); */
                   2809:     /*         } */
                   2810:     /*         printf("\n"); */
                   2811:     /*   } */
                   2812:     /* } */
1.217     brouard  2813:     savm=oldm;
                   2814:     oldm=newm;
1.266     brouard  2815: 
1.217     brouard  2816:     for(j=1; j<=nlstate; j++){
                   2817:       max[j]=0.;
                   2818:       min[j]=1.;
                   2819:     }
                   2820:     for(j=1; j<=nlstate; j++){ 
                   2821:       for(i=1;i<=nlstate;i++){
1.234     brouard  2822:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2823:        bprlim[i][j]= newm[i][j];
                   2824:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2825:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2826:       }
                   2827:     }
1.218     brouard  2828:                
1.217     brouard  2829:     maxmax=0.;
                   2830:     for(i=1; i<=nlstate; i++){
                   2831:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2832:       maxmax=FMAX(maxmax,meandiff[i]);
                   2833:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2834:     } /* i loop */
1.217     brouard  2835:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2836:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2837:     if(maxmax < ftolpl){
1.220     brouard  2838:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2839:       free_vector(min,1,nlstate);
                   2840:       free_vector(max,1,nlstate);
                   2841:       free_vector(meandiff,1,nlstate);
                   2842:       return bprlim;
                   2843:     }
                   2844:   } /* age loop */
                   2845:     /* After some age loop it doesn't converge */
1.247     brouard  2846:   if(first){
                   2847:     first=1;
                   2848:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2849: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2850:   }
                   2851:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2852: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2853:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2854:   free_vector(min,1,nlstate);
                   2855:   free_vector(max,1,nlstate);
                   2856:   free_vector(meandiff,1,nlstate);
                   2857:   
                   2858:   return bprlim; /* should not reach here */
                   2859: }
                   2860: 
1.126     brouard  2861: /*************** transition probabilities ***************/ 
                   2862: 
                   2863: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2864: {
1.138     brouard  2865:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2866:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2867:      model to the ncovmodel covariates (including constant and age).
                   2868:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2869:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2870:      ncth covariate in the global vector x is given by the formula:
                   2871:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2872:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2873:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2874:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2875:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2876:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2877:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2878:   */
                   2879:   double s1, lnpijopii;
1.126     brouard  2880:   /*double t34;*/
1.164     brouard  2881:   int i,j, nc, ii, jj;
1.126     brouard  2882: 
1.223     brouard  2883:   for(i=1; i<= nlstate; i++){
                   2884:     for(j=1; j<i;j++){
                   2885:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2886:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2887:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2888:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2889:       }
                   2890:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2891:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2892:     }
                   2893:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2894:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2895:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2896:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2897:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2898:       }
                   2899:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2900:     }
                   2901:   }
1.218     brouard  2902:   
1.223     brouard  2903:   for(i=1; i<= nlstate; i++){
                   2904:     s1=0;
                   2905:     for(j=1; j<i; j++){
                   2906:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2907:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2908:     }
                   2909:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2910:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2911:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2912:     }
                   2913:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2914:     ps[i][i]=1./(s1+1.);
                   2915:     /* Computing other pijs */
                   2916:     for(j=1; j<i; j++)
                   2917:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2918:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2919:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2920:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2921:   } /* end i */
1.218     brouard  2922:   
1.223     brouard  2923:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2924:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2925:       ps[ii][jj]=0;
                   2926:       ps[ii][ii]=1;
                   2927:     }
                   2928:   }
1.218     brouard  2929:   
                   2930:   
1.223     brouard  2931:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2932:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2933:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2934:   /*   } */
                   2935:   /*   printf("\n "); */
                   2936:   /* } */
                   2937:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2938:   /*
                   2939:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2940:                goto end;*/
1.266     brouard  2941:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2942: }
                   2943: 
1.218     brouard  2944: /*************** backward transition probabilities ***************/ 
                   2945: 
                   2946:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2947: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2948:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2949: {
1.266     brouard  2950:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2951:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2952:    */
1.218     brouard  2953:   int i, ii, j,k;
1.222     brouard  2954:   
                   2955:   double **out, **pmij();
                   2956:   double sumnew=0.;
1.218     brouard  2957:   double agefin;
1.268     brouard  2958:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2959:   double **dnewm, **dsavm, **doldm;
                   2960:   double **bbmij;
                   2961:   
1.218     brouard  2962:   doldm=ddoldms; /* global pointers */
1.222     brouard  2963:   dnewm=ddnewms;
                   2964:   dsavm=ddsavms;
                   2965:   
                   2966:   agefin=cov[2];
1.268     brouard  2967:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2968:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2969:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2970:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2971: 
                   2972:   /* P_x */
1.266     brouard  2973:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2974:   /* outputs pmmij which is a stochastic matrix in row */
                   2975: 
                   2976:   /* Diag(w_x) */
                   2977:   /* Problem with prevacurrent which can be zero */
                   2978:   sumnew=0.;
1.269     brouard  2979:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2980:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2981:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2982:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2983:   }
                   2984:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2985:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2986:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2987:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2988:     }
                   2989:   }else{
                   2990:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2991:       for (j=1;j<=nlstate+ndeath;j++)
                   2992:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2993:     }
                   2994:     /* if(sumnew <0.9){ */
                   2995:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2996:     /* } */
                   2997:   }
                   2998:   k3=0.0;  /* We put the last diagonal to 0 */
                   2999:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3000:       doldm[ii][ii]= k3;
                   3001:   }
                   3002:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3003:   
                   3004:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3005:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3006: 
                   3007:   /* Diag(Sum_i w^i_x p^ij_x */
                   3008:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3009:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3010:     sumnew=0.;
1.222     brouard  3011:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3012:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3013:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3014:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3015:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3016:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3017:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3018:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3019:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3020:        /* }else */
1.268     brouard  3021:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3022:     } /*End ii */
                   3023:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3024: 
                   3025:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3026:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3027:   /* end bmij */
1.266     brouard  3028:   return ps; /*pointer is unchanged */
1.218     brouard  3029: }
1.217     brouard  3030: /*************** transition probabilities ***************/ 
                   3031: 
1.218     brouard  3032: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3033: {
                   3034:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3035:      computes the probability to be observed in state j being in state i by appying the
                   3036:      model to the ncovmodel covariates (including constant and age).
                   3037:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3038:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3039:      ncth covariate in the global vector x is given by the formula:
                   3040:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3041:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3042:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3043:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3044:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3045:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3046:   */
                   3047:   double s1, lnpijopii;
                   3048:   /*double t34;*/
                   3049:   int i,j, nc, ii, jj;
                   3050: 
1.234     brouard  3051:   for(i=1; i<= nlstate; i++){
                   3052:     for(j=1; j<i;j++){
                   3053:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3054:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3055:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3056:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3057:       }
                   3058:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3059:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3060:     }
                   3061:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3062:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3063:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3064:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3065:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3066:       }
                   3067:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3068:     }
                   3069:   }
                   3070:   
                   3071:   for(i=1; i<= nlstate; i++){
                   3072:     s1=0;
                   3073:     for(j=1; j<i; j++){
                   3074:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3075:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3076:     }
                   3077:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3078:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3079:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3080:     }
                   3081:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3082:     ps[i][i]=1./(s1+1.);
                   3083:     /* Computing other pijs */
                   3084:     for(j=1; j<i; j++)
                   3085:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3086:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3087:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3088:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3089:   } /* end i */
                   3090:   
                   3091:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3092:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3093:       ps[ii][jj]=0;
                   3094:       ps[ii][ii]=1;
                   3095:     }
                   3096:   }
                   3097:   /* Added for backcast */ /* Transposed matrix too */
                   3098:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3099:     s1=0.;
                   3100:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3101:       s1+=ps[ii][jj];
                   3102:     }
                   3103:     for(ii=1; ii<= nlstate; ii++){
                   3104:       ps[ii][jj]=ps[ii][jj]/s1;
                   3105:     }
                   3106:   }
                   3107:   /* Transposition */
                   3108:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3109:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3110:       s1=ps[ii][jj];
                   3111:       ps[ii][jj]=ps[jj][ii];
                   3112:       ps[jj][ii]=s1;
                   3113:     }
                   3114:   }
                   3115:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3116:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3117:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3118:   /*   } */
                   3119:   /*   printf("\n "); */
                   3120:   /* } */
                   3121:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3122:   /*
                   3123:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3124:     goto end;*/
                   3125:   return ps;
1.217     brouard  3126: }
                   3127: 
                   3128: 
1.126     brouard  3129: /**************** Product of 2 matrices ******************/
                   3130: 
1.145     brouard  3131: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3132: {
                   3133:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3134:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3135:   /* in, b, out are matrice of pointers which should have been initialized 
                   3136:      before: only the contents of out is modified. The function returns
                   3137:      a pointer to pointers identical to out */
1.145     brouard  3138:   int i, j, k;
1.126     brouard  3139:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3140:     for(k=ncolol; k<=ncoloh; k++){
                   3141:       out[i][k]=0.;
                   3142:       for(j=ncl; j<=nch; j++)
                   3143:        out[i][k] +=in[i][j]*b[j][k];
                   3144:     }
1.126     brouard  3145:   return out;
                   3146: }
                   3147: 
                   3148: 
                   3149: /************* Higher Matrix Product ***************/
                   3150: 
1.235     brouard  3151: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3152: {
1.218     brouard  3153:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3154:      'nhstepm*hstepm*stepm' months (i.e. until
                   3155:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3156:      nhstepm*hstepm matrices. 
                   3157:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3158:      (typically every 2 years instead of every month which is too big 
                   3159:      for the memory).
                   3160:      Model is determined by parameters x and covariates have to be 
                   3161:      included manually here. 
                   3162: 
                   3163:      */
                   3164: 
                   3165:   int i, j, d, h, k;
1.131     brouard  3166:   double **out, cov[NCOVMAX+1];
1.126     brouard  3167:   double **newm;
1.187     brouard  3168:   double agexact;
1.214     brouard  3169:   double agebegin, ageend;
1.126     brouard  3170: 
                   3171:   /* Hstepm could be zero and should return the unit matrix */
                   3172:   for (i=1;i<=nlstate+ndeath;i++)
                   3173:     for (j=1;j<=nlstate+ndeath;j++){
                   3174:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3175:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3176:     }
                   3177:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3178:   for(h=1; h <=nhstepm; h++){
                   3179:     for(d=1; d <=hstepm; d++){
                   3180:       newm=savm;
                   3181:       /* Covariates have to be included here again */
                   3182:       cov[1]=1.;
1.214     brouard  3183:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3184:       cov[2]=agexact;
                   3185:       if(nagesqr==1)
1.227     brouard  3186:        cov[3]= agexact*agexact;
1.235     brouard  3187:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3188:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3189:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3190:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3191:       }
                   3192:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3193:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3194:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3195:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3196:       }
                   3197:       for (k=1; k<=cptcovage;k++){
                   3198:        if(Dummy[Tvar[Tage[k]]]){
                   3199:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3200:        } else{
                   3201:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3202:        }
                   3203:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3204:       }
                   3205:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3206:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3207:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3208:       }
                   3209:       /* for (k=1; k<=cptcovn;k++)  */
                   3210:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3211:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3212:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3213:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3214:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3215:       
                   3216:       
1.126     brouard  3217:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3218:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3219:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3220:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3221:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3222:       /* if((int)age == 70){ */
                   3223:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3224:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3225:       /*         printf("%d pmmij ",i); */
                   3226:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3227:       /*           printf("%f ",pmmij[i][j]); */
                   3228:       /*         } */
                   3229:       /*         printf(" oldm "); */
                   3230:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3231:       /*           printf("%f ",oldm[i][j]); */
                   3232:       /*         } */
                   3233:       /*         printf("\n"); */
                   3234:       /*       } */
                   3235:       /* } */
1.126     brouard  3236:       savm=oldm;
                   3237:       oldm=newm;
                   3238:     }
                   3239:     for(i=1; i<=nlstate+ndeath; i++)
                   3240:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3241:        po[i][j][h]=newm[i][j];
                   3242:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3243:       }
1.128     brouard  3244:     /*printf("h=%d ",h);*/
1.126     brouard  3245:   } /* end h */
1.267     brouard  3246:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3247:   return po;
                   3248: }
                   3249: 
1.217     brouard  3250: /************* Higher Back Matrix Product ***************/
1.218     brouard  3251: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3252: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3253: {
1.266     brouard  3254:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3255:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3256:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3257:      nhstepm*hstepm matrices.
                   3258:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3259:      (typically every 2 years instead of every month which is too big
1.217     brouard  3260:      for the memory).
1.218     brouard  3261:      Model is determined by parameters x and covariates have to be
1.266     brouard  3262:      included manually here. Then we use a call to bmij(x and cov)
                   3263:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3264:   */
1.217     brouard  3265: 
                   3266:   int i, j, d, h, k;
1.266     brouard  3267:   double **out, cov[NCOVMAX+1], **bmij();
                   3268:   double **newm, ***newmm;
1.217     brouard  3269:   double agexact;
                   3270:   double agebegin, ageend;
1.222     brouard  3271:   double **oldm, **savm;
1.217     brouard  3272: 
1.266     brouard  3273:   newmm=po; /* To be saved */
                   3274:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3275:   /* Hstepm could be zero and should return the unit matrix */
                   3276:   for (i=1;i<=nlstate+ndeath;i++)
                   3277:     for (j=1;j<=nlstate+ndeath;j++){
                   3278:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3279:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3280:     }
                   3281:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3282:   for(h=1; h <=nhstepm; h++){
                   3283:     for(d=1; d <=hstepm; d++){
                   3284:       newm=savm;
                   3285:       /* Covariates have to be included here again */
                   3286:       cov[1]=1.;
1.271     brouard  3287:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3288:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3289:       cov[2]=agexact;
                   3290:       if(nagesqr==1)
1.222     brouard  3291:        cov[3]= agexact*agexact;
1.266     brouard  3292:       for (k=1; k<=cptcovn;k++){
                   3293:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3294:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3295:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3296:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3297:       }
1.267     brouard  3298:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3299:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3300:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3301:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3302:       }
                   3303:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3304:        if(Dummy[Tvar[Tage[k]]]){
                   3305:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3306:        } else{
                   3307:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3308:        }
                   3309:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3310:       }
                   3311:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3312:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3313:       }                        
1.217     brouard  3314:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3315:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3316: 
1.218     brouard  3317:       /* Careful transposed matrix */
1.266     brouard  3318:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3319:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3320:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3321:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3322:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3323:       /* if((int)age == 70){ */
                   3324:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3325:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3326:       /*         printf("%d pmmij ",i); */
                   3327:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3328:       /*           printf("%f ",pmmij[i][j]); */
                   3329:       /*         } */
                   3330:       /*         printf(" oldm "); */
                   3331:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3332:       /*           printf("%f ",oldm[i][j]); */
                   3333:       /*         } */
                   3334:       /*         printf("\n"); */
                   3335:       /*       } */
                   3336:       /* } */
                   3337:       savm=oldm;
                   3338:       oldm=newm;
                   3339:     }
                   3340:     for(i=1; i<=nlstate+ndeath; i++)
                   3341:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3342:        po[i][j][h]=newm[i][j];
1.268     brouard  3343:        /* if(h==nhstepm) */
                   3344:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3345:       }
1.268     brouard  3346:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3347:   } /* end h */
1.268     brouard  3348:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3349:   return po;
                   3350: }
                   3351: 
                   3352: 
1.162     brouard  3353: #ifdef NLOPT
                   3354:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3355:   double fret;
                   3356:   double *xt;
                   3357:   int j;
                   3358:   myfunc_data *d2 = (myfunc_data *) pd;
                   3359: /* xt = (p1-1); */
                   3360:   xt=vector(1,n); 
                   3361:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3362: 
                   3363:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3364:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3365:   printf("Function = %.12lf ",fret);
                   3366:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3367:   printf("\n");
                   3368:  free_vector(xt,1,n);
                   3369:   return fret;
                   3370: }
                   3371: #endif
1.126     brouard  3372: 
                   3373: /*************** log-likelihood *************/
                   3374: double func( double *x)
                   3375: {
1.226     brouard  3376:   int i, ii, j, k, mi, d, kk;
                   3377:   int ioffset=0;
                   3378:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3379:   double **out;
                   3380:   double lli; /* Individual log likelihood */
                   3381:   int s1, s2;
1.228     brouard  3382:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3383:   double bbh, survp;
                   3384:   long ipmx;
                   3385:   double agexact;
                   3386:   /*extern weight */
                   3387:   /* We are differentiating ll according to initial status */
                   3388:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3389:   /*for(i=1;i<imx;i++) 
                   3390:     printf(" %d\n",s[4][i]);
                   3391:   */
1.162     brouard  3392: 
1.226     brouard  3393:   ++countcallfunc;
1.162     brouard  3394: 
1.226     brouard  3395:   cov[1]=1.;
1.126     brouard  3396: 
1.226     brouard  3397:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3398:   ioffset=0;
1.226     brouard  3399:   if(mle==1){
                   3400:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3401:       /* Computes the values of the ncovmodel covariates of the model
                   3402:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3403:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3404:         to be observed in j being in i according to the model.
                   3405:       */
1.243     brouard  3406:       ioffset=2+nagesqr ;
1.233     brouard  3407:    /* Fixed */
1.234     brouard  3408:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3409:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3410:       }
1.226     brouard  3411:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3412:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3413:         has been calculated etc */
                   3414:       /* For an individual i, wav[i] gives the number of effective waves */
                   3415:       /* We compute the contribution to Likelihood of each effective transition
                   3416:         mw[mi][i] is real wave of the mi th effectve wave */
                   3417:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3418:         s2=s[mw[mi+1][i]][i];
                   3419:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3420:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3421:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3422:       */
                   3423:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3424:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3425:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3426:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3427:        }
                   3428:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3429:          for (j=1;j<=nlstate+ndeath;j++){
                   3430:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3431:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3432:          }
                   3433:        for(d=0; d<dh[mi][i]; d++){
                   3434:          newm=savm;
                   3435:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3436:          cov[2]=agexact;
                   3437:          if(nagesqr==1)
                   3438:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3439:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3440:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3441:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3442:          else
                   3443:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3444:          }
                   3445:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3446:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3447:          savm=oldm;
                   3448:          oldm=newm;
                   3449:        } /* end mult */
                   3450:        
                   3451:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3452:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3453:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3454:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3455:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3456:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3457:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3458:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3459:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3460:                                 * -stepm/2 to stepm/2 .
                   3461:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3462:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3463:                                 */
1.234     brouard  3464:        s1=s[mw[mi][i]][i];
                   3465:        s2=s[mw[mi+1][i]][i];
                   3466:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3467:        /* bias bh is positive if real duration
                   3468:         * is higher than the multiple of stepm and negative otherwise.
                   3469:         */
                   3470:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3471:        if( s2 > nlstate){ 
                   3472:          /* i.e. if s2 is a death state and if the date of death is known 
                   3473:             then the contribution to the likelihood is the probability to 
                   3474:             die between last step unit time and current  step unit time, 
                   3475:             which is also equal to probability to die before dh 
                   3476:             minus probability to die before dh-stepm . 
                   3477:             In version up to 0.92 likelihood was computed
                   3478:             as if date of death was unknown. Death was treated as any other
                   3479:             health state: the date of the interview describes the actual state
                   3480:             and not the date of a change in health state. The former idea was
                   3481:             to consider that at each interview the state was recorded
                   3482:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3483:             introduced the exact date of death then we should have modified
                   3484:             the contribution of an exact death to the likelihood. This new
                   3485:             contribution is smaller and very dependent of the step unit
                   3486:             stepm. It is no more the probability to die between last interview
                   3487:             and month of death but the probability to survive from last
                   3488:             interview up to one month before death multiplied by the
                   3489:             probability to die within a month. Thanks to Chris
                   3490:             Jackson for correcting this bug.  Former versions increased
                   3491:             mortality artificially. The bad side is that we add another loop
                   3492:             which slows down the processing. The difference can be up to 10%
                   3493:             lower mortality.
                   3494:          */
                   3495:          /* If, at the beginning of the maximization mostly, the
                   3496:             cumulative probability or probability to be dead is
                   3497:             constant (ie = 1) over time d, the difference is equal to
                   3498:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3499:             s1 at precedent wave, to be dead a month before current
                   3500:             wave is equal to probability, being at state s1 at
                   3501:             precedent wave, to be dead at mont of the current
                   3502:             wave. Then the observed probability (that this person died)
                   3503:             is null according to current estimated parameter. In fact,
                   3504:             it should be very low but not zero otherwise the log go to
                   3505:             infinity.
                   3506:          */
1.183     brouard  3507: /* #ifdef INFINITYORIGINAL */
                   3508: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3509: /* #else */
                   3510: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3511: /*         lli=log(mytinydouble); */
                   3512: /*       else */
                   3513: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3514: /* #endif */
1.226     brouard  3515:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3516:          
1.226     brouard  3517:        } else if  ( s2==-1 ) { /* alive */
                   3518:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3519:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3520:          /*survp += out[s1][j]; */
                   3521:          lli= log(survp);
                   3522:        }
                   3523:        else if  (s2==-4) { 
                   3524:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3525:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3526:          lli= log(survp); 
                   3527:        } 
                   3528:        else if  (s2==-5) { 
                   3529:          for (j=1,survp=0. ; j<=2; j++)  
                   3530:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3531:          lli= log(survp); 
                   3532:        } 
                   3533:        else{
                   3534:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3535:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3536:        } 
                   3537:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3538:        /*if(lli ==000.0)*/
                   3539:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3540:        ipmx +=1;
                   3541:        sw += weight[i];
                   3542:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3543:        /* if (lli < log(mytinydouble)){ */
                   3544:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3545:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3546:        /* } */
                   3547:       } /* end of wave */
                   3548:     } /* end of individual */
                   3549:   }  else if(mle==2){
                   3550:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3551:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3552:       for(mi=1; mi<= wav[i]-1; mi++){
                   3553:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3554:          for (j=1;j<=nlstate+ndeath;j++){
                   3555:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3556:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3557:          }
                   3558:        for(d=0; d<=dh[mi][i]; d++){
                   3559:          newm=savm;
                   3560:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3561:          cov[2]=agexact;
                   3562:          if(nagesqr==1)
                   3563:            cov[3]= agexact*agexact;
                   3564:          for (kk=1; kk<=cptcovage;kk++) {
                   3565:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3566:          }
                   3567:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3568:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3569:          savm=oldm;
                   3570:          oldm=newm;
                   3571:        } /* end mult */
                   3572:       
                   3573:        s1=s[mw[mi][i]][i];
                   3574:        s2=s[mw[mi+1][i]][i];
                   3575:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3576:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3577:        ipmx +=1;
                   3578:        sw += weight[i];
                   3579:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3580:       } /* end of wave */
                   3581:     } /* end of individual */
                   3582:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3583:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3584:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3585:       for(mi=1; mi<= wav[i]-1; mi++){
                   3586:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3587:          for (j=1;j<=nlstate+ndeath;j++){
                   3588:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3589:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3590:          }
                   3591:        for(d=0; d<dh[mi][i]; d++){
                   3592:          newm=savm;
                   3593:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3594:          cov[2]=agexact;
                   3595:          if(nagesqr==1)
                   3596:            cov[3]= agexact*agexact;
                   3597:          for (kk=1; kk<=cptcovage;kk++) {
                   3598:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3599:          }
                   3600:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3601:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3602:          savm=oldm;
                   3603:          oldm=newm;
                   3604:        } /* end mult */
                   3605:       
                   3606:        s1=s[mw[mi][i]][i];
                   3607:        s2=s[mw[mi+1][i]][i];
                   3608:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3609:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3610:        ipmx +=1;
                   3611:        sw += weight[i];
                   3612:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3613:       } /* end of wave */
                   3614:     } /* end of individual */
                   3615:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3616:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3617:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3618:       for(mi=1; mi<= wav[i]-1; mi++){
                   3619:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3620:          for (j=1;j<=nlstate+ndeath;j++){
                   3621:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3622:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3623:          }
                   3624:        for(d=0; d<dh[mi][i]; d++){
                   3625:          newm=savm;
                   3626:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3627:          cov[2]=agexact;
                   3628:          if(nagesqr==1)
                   3629:            cov[3]= agexact*agexact;
                   3630:          for (kk=1; kk<=cptcovage;kk++) {
                   3631:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3632:          }
1.126     brouard  3633:        
1.226     brouard  3634:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3635:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3636:          savm=oldm;
                   3637:          oldm=newm;
                   3638:        } /* end mult */
                   3639:       
                   3640:        s1=s[mw[mi][i]][i];
                   3641:        s2=s[mw[mi+1][i]][i];
                   3642:        if( s2 > nlstate){ 
                   3643:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3644:        } else if  ( s2==-1 ) { /* alive */
                   3645:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3646:            survp += out[s1][j];
                   3647:          lli= log(survp);
                   3648:        }else{
                   3649:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3650:        }
                   3651:        ipmx +=1;
                   3652:        sw += weight[i];
                   3653:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3654: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3655:       } /* end of wave */
                   3656:     } /* end of individual */
                   3657:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3658:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3659:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3660:       for(mi=1; mi<= wav[i]-1; mi++){
                   3661:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3662:          for (j=1;j<=nlstate+ndeath;j++){
                   3663:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3664:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3665:          }
                   3666:        for(d=0; d<dh[mi][i]; d++){
                   3667:          newm=savm;
                   3668:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3669:          cov[2]=agexact;
                   3670:          if(nagesqr==1)
                   3671:            cov[3]= agexact*agexact;
                   3672:          for (kk=1; kk<=cptcovage;kk++) {
                   3673:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3674:          }
1.126     brouard  3675:        
1.226     brouard  3676:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3677:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3678:          savm=oldm;
                   3679:          oldm=newm;
                   3680:        } /* end mult */
                   3681:       
                   3682:        s1=s[mw[mi][i]][i];
                   3683:        s2=s[mw[mi+1][i]][i];
                   3684:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3685:        ipmx +=1;
                   3686:        sw += weight[i];
                   3687:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3688:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3689:       } /* end of wave */
                   3690:     } /* end of individual */
                   3691:   } /* End of if */
                   3692:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3693:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3694:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3695:   return -l;
1.126     brouard  3696: }
                   3697: 
                   3698: /*************** log-likelihood *************/
                   3699: double funcone( double *x)
                   3700: {
1.228     brouard  3701:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3702:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3703:   int ioffset=0;
1.131     brouard  3704:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3705:   double **out;
                   3706:   double lli; /* Individual log likelihood */
                   3707:   double llt;
                   3708:   int s1, s2;
1.228     brouard  3709:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3710: 
1.126     brouard  3711:   double bbh, survp;
1.187     brouard  3712:   double agexact;
1.214     brouard  3713:   double agebegin, ageend;
1.126     brouard  3714:   /*extern weight */
                   3715:   /* We are differentiating ll according to initial status */
                   3716:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3717:   /*for(i=1;i<imx;i++) 
                   3718:     printf(" %d\n",s[4][i]);
                   3719:   */
                   3720:   cov[1]=1.;
                   3721: 
                   3722:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3723:   ioffset=0;
                   3724:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3725:     /* ioffset=2+nagesqr+cptcovage; */
                   3726:     ioffset=2+nagesqr;
1.232     brouard  3727:     /* Fixed */
1.224     brouard  3728:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3729:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3730:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3731:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3732: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3733: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3734: /*    cov[2+6]=covar[2][i]; V2  */
                   3735: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3736: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3737: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3738: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3739: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3740: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3741:     }
1.232     brouard  3742:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3743:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3744:     /* } */
1.231     brouard  3745:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3746:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3747:     /* } */
1.225     brouard  3748:     
1.233     brouard  3749: 
                   3750:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3751:     /* Wave varying (but not age varying) */
                   3752:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3753:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3754:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3755:       }
1.232     brouard  3756:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3757:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3758:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3759:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3760:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3761:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3762:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3763:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3764:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3765:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3766:       /* } */
1.126     brouard  3767:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3768:        for (j=1;j<=nlstate+ndeath;j++){
                   3769:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3770:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3771:        }
1.214     brouard  3772:       
                   3773:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3774:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3775:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3776:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3777:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3778:          and mw[mi+1][i]. dh depends on stepm.*/
                   3779:        newm=savm;
1.247     brouard  3780:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3781:        cov[2]=agexact;
                   3782:        if(nagesqr==1)
                   3783:          cov[3]= agexact*agexact;
                   3784:        for (kk=1; kk<=cptcovage;kk++) {
                   3785:          if(!FixedV[Tvar[Tage[kk]]])
                   3786:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3787:          else
                   3788:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3789:        }
                   3790:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3791:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3792:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3793:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3794:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3795:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3796:        savm=oldm;
                   3797:        oldm=newm;
1.126     brouard  3798:       } /* end mult */
                   3799:       
                   3800:       s1=s[mw[mi][i]][i];
                   3801:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3802:       /* if(s2==-1){ */
1.268     brouard  3803:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3804:       /*       /\* exit(1); *\/ */
                   3805:       /* } */
1.126     brouard  3806:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3807:       /* bias is positive if real duration
                   3808:        * is higher than the multiple of stepm and negative otherwise.
                   3809:        */
                   3810:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3811:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3812:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3813:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3814:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3815:        lli= log(survp);
1.126     brouard  3816:       }else if (mle==1){
1.242     brouard  3817:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3818:       } else if(mle==2){
1.242     brouard  3819:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3820:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3821:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3822:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3823:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3824:       } else{  /* mle=0 back to 1 */
1.242     brouard  3825:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3826:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3827:       } /* End of if */
                   3828:       ipmx +=1;
                   3829:       sw += weight[i];
                   3830:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3831:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3832:       if(globpr){
1.246     brouard  3833:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3834:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3835:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3836:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3837:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3838:          llt +=ll[k]*gipmx/gsw;
                   3839:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3840:        }
                   3841:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3842:       }
1.232     brouard  3843:        } /* end of wave */
                   3844: } /* end of individual */
                   3845: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3846: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3847: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3848: if(globpr==0){ /* First time we count the contributions and weights */
                   3849:        gipmx=ipmx;
                   3850:        gsw=sw;
                   3851: }
                   3852: return -l;
1.126     brouard  3853: }
                   3854: 
                   3855: 
                   3856: /*************** function likelione ***********/
                   3857: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3858: {
                   3859:   /* This routine should help understanding what is done with 
                   3860:      the selection of individuals/waves and
                   3861:      to check the exact contribution to the likelihood.
                   3862:      Plotting could be done.
                   3863:    */
                   3864:   int k;
                   3865: 
                   3866:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3867:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3868:     strcat(fileresilk,fileresu);
1.126     brouard  3869:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3870:       printf("Problem with resultfile: %s\n", fileresilk);
                   3871:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3872:     }
1.214     brouard  3873:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3874:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3875:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3876:     for(k=1; k<=nlstate; k++) 
                   3877:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3878:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3879:   }
                   3880: 
                   3881:   *fretone=(*funcone)(p);
                   3882:   if(*globpri !=0){
                   3883:     fclose(ficresilk);
1.205     brouard  3884:     if (mle ==0)
                   3885:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3886:     else if(mle >=1)
                   3887:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3888:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3889:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3890:       
                   3891:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3892:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3893: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3894:     }
1.207     brouard  3895:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3896: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3897:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3898: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3899:     fflush(fichtm);
1.205     brouard  3900:   }
1.126     brouard  3901:   return;
                   3902: }
                   3903: 
                   3904: 
                   3905: /*********** Maximum Likelihood Estimation ***************/
                   3906: 
                   3907: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3908: {
1.165     brouard  3909:   int i,j, iter=0;
1.126     brouard  3910:   double **xi;
                   3911:   double fret;
                   3912:   double fretone; /* Only one call to likelihood */
                   3913:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3914: 
                   3915: #ifdef NLOPT
                   3916:   int creturn;
                   3917:   nlopt_opt opt;
                   3918:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3919:   double *lb;
                   3920:   double minf; /* the minimum objective value, upon return */
                   3921:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3922:   myfunc_data dinst, *d = &dinst;
                   3923: #endif
                   3924: 
                   3925: 
1.126     brouard  3926:   xi=matrix(1,npar,1,npar);
                   3927:   for (i=1;i<=npar;i++)
                   3928:     for (j=1;j<=npar;j++)
                   3929:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3930:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3931:   strcpy(filerespow,"POW_"); 
1.126     brouard  3932:   strcat(filerespow,fileres);
                   3933:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3934:     printf("Problem with resultfile: %s\n", filerespow);
                   3935:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3936:   }
                   3937:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3938:   for (i=1;i<=nlstate;i++)
                   3939:     for(j=1;j<=nlstate+ndeath;j++)
                   3940:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3941:   fprintf(ficrespow,"\n");
1.162     brouard  3942: #ifdef POWELL
1.126     brouard  3943:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3944: #endif
1.126     brouard  3945: 
1.162     brouard  3946: #ifdef NLOPT
                   3947: #ifdef NEWUOA
                   3948:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3949: #else
                   3950:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3951: #endif
                   3952:   lb=vector(0,npar-1);
                   3953:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3954:   nlopt_set_lower_bounds(opt, lb);
                   3955:   nlopt_set_initial_step1(opt, 0.1);
                   3956:   
                   3957:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3958:   d->function = func;
                   3959:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3960:   nlopt_set_min_objective(opt, myfunc, d);
                   3961:   nlopt_set_xtol_rel(opt, ftol);
                   3962:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3963:     printf("nlopt failed! %d\n",creturn); 
                   3964:   }
                   3965:   else {
                   3966:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3967:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3968:     iter=1; /* not equal */
                   3969:   }
                   3970:   nlopt_destroy(opt);
                   3971: #endif
1.126     brouard  3972:   free_matrix(xi,1,npar,1,npar);
                   3973:   fclose(ficrespow);
1.203     brouard  3974:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3975:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3976:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3977: 
                   3978: }
                   3979: 
                   3980: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3981: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3982: {
                   3983:   double  **a,**y,*x,pd;
1.203     brouard  3984:   /* double **hess; */
1.164     brouard  3985:   int i, j;
1.126     brouard  3986:   int *indx;
                   3987: 
                   3988:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3989:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3990:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3991:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3992:   double gompertz(double p[]);
1.203     brouard  3993:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3994: 
                   3995:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3996:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3997:   for (i=1;i<=npar;i++){
1.203     brouard  3998:     printf("%d-",i);fflush(stdout);
                   3999:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4000:    
                   4001:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4002:     
                   4003:     /*  printf(" %f ",p[i]);
                   4004:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4005:   }
                   4006:   
                   4007:   for (i=1;i<=npar;i++) {
                   4008:     for (j=1;j<=npar;j++)  {
                   4009:       if (j>i) { 
1.203     brouard  4010:        printf(".%d-%d",i,j);fflush(stdout);
                   4011:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4012:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4013:        
                   4014:        hess[j][i]=hess[i][j];    
                   4015:        /*printf(" %lf ",hess[i][j]);*/
                   4016:       }
                   4017:     }
                   4018:   }
                   4019:   printf("\n");
                   4020:   fprintf(ficlog,"\n");
                   4021: 
                   4022:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4023:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4024:   
                   4025:   a=matrix(1,npar,1,npar);
                   4026:   y=matrix(1,npar,1,npar);
                   4027:   x=vector(1,npar);
                   4028:   indx=ivector(1,npar);
                   4029:   for (i=1;i<=npar;i++)
                   4030:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4031:   ludcmp(a,npar,indx,&pd);
                   4032: 
                   4033:   for (j=1;j<=npar;j++) {
                   4034:     for (i=1;i<=npar;i++) x[i]=0;
                   4035:     x[j]=1;
                   4036:     lubksb(a,npar,indx,x);
                   4037:     for (i=1;i<=npar;i++){ 
                   4038:       matcov[i][j]=x[i];
                   4039:     }
                   4040:   }
                   4041: 
                   4042:   printf("\n#Hessian matrix#\n");
                   4043:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4044:   for (i=1;i<=npar;i++) { 
                   4045:     for (j=1;j<=npar;j++) { 
1.203     brouard  4046:       printf("%.6e ",hess[i][j]);
                   4047:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4048:     }
                   4049:     printf("\n");
                   4050:     fprintf(ficlog,"\n");
                   4051:   }
                   4052: 
1.203     brouard  4053:   /* printf("\n#Covariance matrix#\n"); */
                   4054:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4055:   /* for (i=1;i<=npar;i++) {  */
                   4056:   /*   for (j=1;j<=npar;j++) {  */
                   4057:   /*     printf("%.6e ",matcov[i][j]); */
                   4058:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4059:   /*   } */
                   4060:   /*   printf("\n"); */
                   4061:   /*   fprintf(ficlog,"\n"); */
                   4062:   /* } */
                   4063: 
1.126     brouard  4064:   /* Recompute Inverse */
1.203     brouard  4065:   /* for (i=1;i<=npar;i++) */
                   4066:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4067:   /* ludcmp(a,npar,indx,&pd); */
                   4068: 
                   4069:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4070: 
                   4071:   /* for (j=1;j<=npar;j++) { */
                   4072:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4073:   /*   x[j]=1; */
                   4074:   /*   lubksb(a,npar,indx,x); */
                   4075:   /*   for (i=1;i<=npar;i++){  */
                   4076:   /*     y[i][j]=x[i]; */
                   4077:   /*     printf("%.3e ",y[i][j]); */
                   4078:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4079:   /*   } */
                   4080:   /*   printf("\n"); */
                   4081:   /*   fprintf(ficlog,"\n"); */
                   4082:   /* } */
                   4083: 
                   4084:   /* Verifying the inverse matrix */
                   4085: #ifdef DEBUGHESS
                   4086:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4087: 
1.203     brouard  4088:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4089:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4090: 
                   4091:   for (j=1;j<=npar;j++) {
                   4092:     for (i=1;i<=npar;i++){ 
1.203     brouard  4093:       printf("%.2f ",y[i][j]);
                   4094:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4095:     }
                   4096:     printf("\n");
                   4097:     fprintf(ficlog,"\n");
                   4098:   }
1.203     brouard  4099: #endif
1.126     brouard  4100: 
                   4101:   free_matrix(a,1,npar,1,npar);
                   4102:   free_matrix(y,1,npar,1,npar);
                   4103:   free_vector(x,1,npar);
                   4104:   free_ivector(indx,1,npar);
1.203     brouard  4105:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4106: 
                   4107: 
                   4108: }
                   4109: 
                   4110: /*************** hessian matrix ****************/
                   4111: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4112: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4113:   int i;
                   4114:   int l=1, lmax=20;
1.203     brouard  4115:   double k1,k2, res, fx;
1.132     brouard  4116:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4117:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4118:   int k=0,kmax=10;
                   4119:   double l1;
                   4120: 
                   4121:   fx=func(x);
                   4122:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4123:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4124:     l1=pow(10,l);
                   4125:     delts=delt;
                   4126:     for(k=1 ; k <kmax; k=k+1){
                   4127:       delt = delta*(l1*k);
                   4128:       p2[theta]=x[theta] +delt;
1.145     brouard  4129:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4130:       p2[theta]=x[theta]-delt;
                   4131:       k2=func(p2)-fx;
                   4132:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4133:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4134:       
1.203     brouard  4135: #ifdef DEBUGHESSII
1.126     brouard  4136:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4137:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4138: #endif
                   4139:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4140:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4141:        k=kmax;
                   4142:       }
                   4143:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4144:        k=kmax; l=lmax*10;
1.126     brouard  4145:       }
                   4146:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4147:        delts=delt;
                   4148:       }
1.203     brouard  4149:     } /* End loop k */
1.126     brouard  4150:   }
                   4151:   delti[theta]=delts;
                   4152:   return res; 
                   4153:   
                   4154: }
                   4155: 
1.203     brouard  4156: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4157: {
                   4158:   int i;
1.164     brouard  4159:   int l=1, lmax=20;
1.126     brouard  4160:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4161:   double p2[MAXPARM+1];
1.203     brouard  4162:   int k, kmax=1;
                   4163:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4164: 
                   4165:   int firstime=0;
1.203     brouard  4166:   
1.126     brouard  4167:   fx=func(x);
1.203     brouard  4168:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4169:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4170:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4171:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4172:     k1=func(p2)-fx;
                   4173:   
1.203     brouard  4174:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4175:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4176:     k2=func(p2)-fx;
                   4177:   
1.203     brouard  4178:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4179:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4180:     k3=func(p2)-fx;
                   4181:   
1.203     brouard  4182:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4183:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4184:     k4=func(p2)-fx;
1.203     brouard  4185:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4186:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4187:       firstime=1;
1.203     brouard  4188:       kmax=kmax+10;
1.208     brouard  4189:     }
                   4190:     if(kmax >=10 || firstime ==1){
1.246     brouard  4191:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4192:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4193:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4194:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4195:     }
                   4196: #ifdef DEBUGHESSIJ
                   4197:     v1=hess[thetai][thetai];
                   4198:     v2=hess[thetaj][thetaj];
                   4199:     cv12=res;
                   4200:     /* Computing eigen value of Hessian matrix */
                   4201:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4202:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4203:     if ((lc2 <0) || (lc1 <0) ){
                   4204:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4205:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4206:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4207:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4208:     }
1.126     brouard  4209: #endif
                   4210:   }
                   4211:   return res;
                   4212: }
                   4213: 
1.203     brouard  4214:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4215: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4216: /* { */
                   4217: /*   int i; */
                   4218: /*   int l=1, lmax=20; */
                   4219: /*   double k1,k2,k3,k4,res,fx; */
                   4220: /*   double p2[MAXPARM+1]; */
                   4221: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4222: /*   int k=0,kmax=10; */
                   4223: /*   double l1; */
                   4224:   
                   4225: /*   fx=func(x); */
                   4226: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4227: /*     l1=pow(10,l); */
                   4228: /*     delts=delt; */
                   4229: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4230: /*       delt = delti*(l1*k); */
                   4231: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4232: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4233: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4234: /*       k1=func(p2)-fx; */
                   4235:       
                   4236: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4237: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4238: /*       k2=func(p2)-fx; */
                   4239:       
                   4240: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4241: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4242: /*       k3=func(p2)-fx; */
                   4243:       
                   4244: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4245: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4246: /*       k4=func(p2)-fx; */
                   4247: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4248: /* #ifdef DEBUGHESSIJ */
                   4249: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4250: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4251: /* #endif */
                   4252: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4253: /*     k=kmax; */
                   4254: /*       } */
                   4255: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4256: /*     k=kmax; l=lmax*10; */
                   4257: /*       } */
                   4258: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4259: /*     delts=delt; */
                   4260: /*       } */
                   4261: /*     } /\* End loop k *\/ */
                   4262: /*   } */
                   4263: /*   delti[theta]=delts; */
                   4264: /*   return res;  */
                   4265: /* } */
                   4266: 
                   4267: 
1.126     brouard  4268: /************** Inverse of matrix **************/
                   4269: void ludcmp(double **a, int n, int *indx, double *d) 
                   4270: { 
                   4271:   int i,imax,j,k; 
                   4272:   double big,dum,sum,temp; 
                   4273:   double *vv; 
                   4274:  
                   4275:   vv=vector(1,n); 
                   4276:   *d=1.0; 
                   4277:   for (i=1;i<=n;i++) { 
                   4278:     big=0.0; 
                   4279:     for (j=1;j<=n;j++) 
                   4280:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4281:     if (big == 0.0){
                   4282:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4283:       for (j=1;j<=n;j++) {
                   4284:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4285:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4286:       }
                   4287:       fflush(ficlog);
                   4288:       fclose(ficlog);
                   4289:       nrerror("Singular matrix in routine ludcmp"); 
                   4290:     }
1.126     brouard  4291:     vv[i]=1.0/big; 
                   4292:   } 
                   4293:   for (j=1;j<=n;j++) { 
                   4294:     for (i=1;i<j;i++) { 
                   4295:       sum=a[i][j]; 
                   4296:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4297:       a[i][j]=sum; 
                   4298:     } 
                   4299:     big=0.0; 
                   4300:     for (i=j;i<=n;i++) { 
                   4301:       sum=a[i][j]; 
                   4302:       for (k=1;k<j;k++) 
                   4303:        sum -= a[i][k]*a[k][j]; 
                   4304:       a[i][j]=sum; 
                   4305:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4306:        big=dum; 
                   4307:        imax=i; 
                   4308:       } 
                   4309:     } 
                   4310:     if (j != imax) { 
                   4311:       for (k=1;k<=n;k++) { 
                   4312:        dum=a[imax][k]; 
                   4313:        a[imax][k]=a[j][k]; 
                   4314:        a[j][k]=dum; 
                   4315:       } 
                   4316:       *d = -(*d); 
                   4317:       vv[imax]=vv[j]; 
                   4318:     } 
                   4319:     indx[j]=imax; 
                   4320:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4321:     if (j != n) { 
                   4322:       dum=1.0/(a[j][j]); 
                   4323:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4324:     } 
                   4325:   } 
                   4326:   free_vector(vv,1,n);  /* Doesn't work */
                   4327: ;
                   4328: } 
                   4329: 
                   4330: void lubksb(double **a, int n, int *indx, double b[]) 
                   4331: { 
                   4332:   int i,ii=0,ip,j; 
                   4333:   double sum; 
                   4334:  
                   4335:   for (i=1;i<=n;i++) { 
                   4336:     ip=indx[i]; 
                   4337:     sum=b[ip]; 
                   4338:     b[ip]=b[i]; 
                   4339:     if (ii) 
                   4340:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4341:     else if (sum) ii=i; 
                   4342:     b[i]=sum; 
                   4343:   } 
                   4344:   for (i=n;i>=1;i--) { 
                   4345:     sum=b[i]; 
                   4346:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4347:     b[i]=sum/a[i][i]; 
                   4348:   } 
                   4349: } 
                   4350: 
                   4351: void pstamp(FILE *fichier)
                   4352: {
1.196     brouard  4353:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4354: }
                   4355: 
1.253     brouard  4356: 
                   4357: 
1.126     brouard  4358: /************ Frequencies ********************/
1.251     brouard  4359: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4360:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4361:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4362: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4363:   
1.265     brouard  4364:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4365:   int iind=0, iage=0;
                   4366:   int mi; /* Effective wave */
                   4367:   int first;
                   4368:   double ***freq; /* Frequencies */
1.268     brouard  4369:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4370:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.283   ! brouard  4371:   double *meanq, *idq;
1.226     brouard  4372:   double **meanqt;
                   4373:   double *pp, **prop, *posprop, *pospropt;
                   4374:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4375:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4376:   double agebegin, ageend;
                   4377:     
                   4378:   pp=vector(1,nlstate);
1.251     brouard  4379:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4380:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4381:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4382:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4383:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283   ! brouard  4384:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4385:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4386:   strcpy(fileresp,"P_");
                   4387:   strcat(fileresp,fileresu);
                   4388:   /*strcat(fileresphtm,fileresu);*/
                   4389:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4390:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4391:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4392:     exit(0);
                   4393:   }
1.240     brouard  4394:   
1.226     brouard  4395:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4396:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4397:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4398:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4399:     fflush(ficlog);
                   4400:     exit(70); 
                   4401:   }
                   4402:   else{
                   4403:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4404: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4405: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4406:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4407:   }
1.237     brouard  4408:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4409:   
1.226     brouard  4410:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4411:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4412:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4413:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4414:     fflush(ficlog);
                   4415:     exit(70); 
1.240     brouard  4416:   } else{
1.226     brouard  4417:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4418: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4419: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4420:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4421:   }
1.240     brouard  4422:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4423:   
1.253     brouard  4424:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4425:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4426:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4427:   j1=0;
1.126     brouard  4428:   
1.227     brouard  4429:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4430:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4431:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4432:   
                   4433:   
1.226     brouard  4434:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4435:      reference=low_education V1=0,V2=0
                   4436:      med_educ                V1=1 V2=0, 
                   4437:      high_educ               V1=0 V2=1
                   4438:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4439:   */
1.249     brouard  4440:   dateintsum=0;
                   4441:   k2cpt=0;
                   4442: 
1.253     brouard  4443:   if(cptcoveff == 0 )
1.265     brouard  4444:     nl=1;  /* Constant and age model only */
1.253     brouard  4445:   else
                   4446:     nl=2;
1.265     brouard  4447: 
                   4448:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4449:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4450:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4451:    *     freq[s1][s2][iage] =0.
                   4452:    *     Loop on iind
                   4453:    *       ++freq[s1][s2][iage] weighted
                   4454:    *     end iind
                   4455:    *     if covariate and j!0
                   4456:    *       headers Variable on one line
                   4457:    *     endif cov j!=0
                   4458:    *     header of frequency table by age
                   4459:    *     Loop on age
                   4460:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4461:    *       pos+=freq[s1][s2][iage] weighted
                   4462:    *       Loop on s1 initial state
                   4463:    *         fprintf(ficresp
                   4464:    *       end s1
                   4465:    *     end age
                   4466:    *     if j!=0 computes starting values
                   4467:    *     end compute starting values
                   4468:    *   end j1
                   4469:    * end nl 
                   4470:    */
1.253     brouard  4471:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4472:     if(nj==1)
                   4473:       j=0;  /* First pass for the constant */
1.265     brouard  4474:     else{
1.253     brouard  4475:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4476:     }
1.251     brouard  4477:     first=1;
1.265     brouard  4478:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4479:       posproptt=0.;
                   4480:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4481:        scanf("%d", i);*/
                   4482:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4483:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4484:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4485:            freq[i][s2][m]=0;
1.251     brouard  4486:       
                   4487:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4488:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4489:          prop[i][m]=0;
                   4490:        posprop[i]=0;
                   4491:        pospropt[i]=0;
                   4492:       }
1.283   ! brouard  4493:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
        !          4494:         idq[z1]+=0.;
        !          4495:         meanq[z1]+=0.;
        !          4496:       }
        !          4497:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4498:       /*   for(m=1;m<=lastpass;m++){ */
1.283   ! brouard  4499:       /*         meanqt[m][z1]=0.; */
        !          4500:       /*       } */
        !          4501:       /* }       */
1.251     brouard  4502:       /* dateintsum=0; */
                   4503:       /* k2cpt=0; */
                   4504:       
1.265     brouard  4505:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4506:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4507:        bool=1;
                   4508:        if(j !=0){
                   4509:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4510:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.283   ! brouard  4511:              /* for (z1=1; z1<= nqfveff; z1++) { */
1.251     brouard  4512:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4513:              /* } */
                   4514:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4515:                /* if(Tvaraff[z1] ==-20){ */
                   4516:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4517:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4518:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4519:                /* }else  */
                   4520:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4521:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4522:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4523:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4524:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4525:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4526:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4527:                } /* Onlyf fixed */
                   4528:              } /* end z1 */
                   4529:            } /* cptcovn > 0 */
                   4530:          } /* end any */
                   4531:        }/* end j==0 */
1.265     brouard  4532:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4533:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4534:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4535:            m=mw[mi][iind];
                   4536:            if(j!=0){
                   4537:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4538:                for (z1=1; z1<=cptcoveff; z1++) {
                   4539:                  if( Fixed[Tmodelind[z1]]==1){
                   4540:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4541:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4542:                                                                                      value is -1, we don't select. It differs from the 
                   4543:                                                                                      constant and age model which counts them. */
                   4544:                      bool=0; /* not selected */
                   4545:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4546:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4547:                      bool=0;
                   4548:                    }
                   4549:                  }
                   4550:                }
                   4551:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4552:            } /* end j==0 */
                   4553:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4554:            if(bool==1){
                   4555:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4556:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4557:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4558:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4559:              if(m >=firstpass && m <=lastpass){
                   4560:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4561:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4562:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4563:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4564:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4565:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4566:                if (m<lastpass) {
                   4567:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4568:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4569:                  if(s[m][iind]==-1)
                   4570:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4571:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4572:                  /* if((int)agev[m][iind] == 55) */
                   4573:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4574:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4575:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4576:                }
1.283   ! brouard  4577:                for (z1=1; z1<= nqfveff; z1++) {
        !          4578:                  idq[z1]++;
        !          4579:                  meanq[z1]+=covar[ncovcol+z1][iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
        !          4580:                  /* meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
        !          4581:                }
1.251     brouard  4582:              } /* end if between passes */  
                   4583:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4584:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4585:                k2cpt++;
                   4586:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4587:              }
1.251     brouard  4588:            }else{
                   4589:              bool=1;
                   4590:            }/* end bool 2 */
                   4591:          } /* end m */
                   4592:        } /* end bool */
                   4593:       } /* end iind = 1 to imx */
                   4594:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4595:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4596:       
                   4597:       
                   4598:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4599:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4600:         pstamp(ficresp);
1.251     brouard  4601:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4602:         pstamp(ficresp);
1.251     brouard  4603:        printf( "\n#********** Variable "); 
                   4604:        fprintf(ficresp, "\n#********** Variable "); 
                   4605:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4606:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4607:        fprintf(ficlog, "\n#********** Variable "); 
                   4608:        for (z1=1; z1<=cptcoveff; z1++){
                   4609:          if(!FixedV[Tvaraff[z1]]){
                   4610:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4611:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4612:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4613:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4614:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4615:          }else{
1.251     brouard  4616:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4617:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4618:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4619:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4620:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4621:          }
                   4622:        }
                   4623:        printf( "**********\n#");
                   4624:        fprintf(ficresp, "**********\n#");
                   4625:        fprintf(ficresphtm, "**********</h3>\n");
                   4626:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4627:        fprintf(ficlog, "**********\n");
                   4628:       }
1.283   ! brouard  4629:            /*
        !          4630:              Printing means of quantitative variables if any
        !          4631:            */
        !          4632:            for (z1=1; z1<= nqfveff; z1++) {
        !          4633:              fprintf(ficresphtmfr,"V quantitative id %d, number of idividuals= %f, sum=%f", z1, idq[z1], meanq[z1]);
        !          4634:              fprintf(ficresphtmfr,", mean=%f<p>\n",meanq[z1]/idq[z1]);
        !          4635:            }
        !          4636:            /* for (z1=1; z1<= nqtveff; z1++) { */
        !          4637:            /*  for(m=1;m<=lastpass;m++){ */
        !          4638:            /*    fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
        !          4639:            /*   } */
        !          4640:            /* } */
        !          4641: 
1.251     brouard  4642:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4643:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4644:         fprintf(ficresp, " Age");
                   4645:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4646:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4647:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4648:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4649:       }
1.265     brouard  4650:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4651:       fprintf(ficresphtm, "\n");
                   4652:       
                   4653:       /* Header of frequency table by age */
                   4654:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4655:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4656:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4657:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4658:          if(s2!=0 && m!=0)
                   4659:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4660:        }
1.226     brouard  4661:       }
1.251     brouard  4662:       fprintf(ficresphtmfr, "\n");
                   4663:     
                   4664:       /* For each age */
                   4665:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4666:        fprintf(ficresphtm,"<tr>");
                   4667:        if(iage==iagemax+1){
                   4668:          fprintf(ficlog,"1");
                   4669:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4670:        }else if(iage==iagemax+2){
                   4671:          fprintf(ficlog,"0");
                   4672:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4673:        }else if(iage==iagemax+3){
                   4674:          fprintf(ficlog,"Total");
                   4675:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4676:        }else{
1.240     brouard  4677:          if(first==1){
1.251     brouard  4678:            first=0;
                   4679:            printf("See log file for details...\n");
                   4680:          }
                   4681:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4682:          fprintf(ficlog,"Age %d", iage);
                   4683:        }
1.265     brouard  4684:        for(s1=1; s1 <=nlstate ; s1++){
                   4685:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4686:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4687:        }
1.265     brouard  4688:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4689:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4690:            pos += freq[s1][m][iage];
                   4691:          if(pp[s1]>=1.e-10){
1.251     brouard  4692:            if(first==1){
1.265     brouard  4693:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4694:            }
1.265     brouard  4695:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4696:          }else{
                   4697:            if(first==1)
1.265     brouard  4698:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4699:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4700:          }
                   4701:        }
                   4702:       
1.265     brouard  4703:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4704:          /* posprop[s1]=0; */
                   4705:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4706:            pp[s1] += freq[s1][m][iage];
                   4707:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4708:       
                   4709:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4710:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4711:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4712:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4713:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4714:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4715:        }
                   4716:        
                   4717:        /* Writing ficresp */
                   4718:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4719:           if( iage <= iagemax){
                   4720:            fprintf(ficresp," %d",iage);
                   4721:           }
                   4722:         }else if( nj==2){
                   4723:           if( iage <= iagemax){
                   4724:            fprintf(ficresp," %d",iage);
                   4725:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4726:           }
1.240     brouard  4727:        }
1.265     brouard  4728:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4729:          if(pos>=1.e-5){
1.251     brouard  4730:            if(first==1)
1.265     brouard  4731:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4732:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4733:          }else{
                   4734:            if(first==1)
1.265     brouard  4735:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4736:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4737:          }
                   4738:          if( iage <= iagemax){
                   4739:            if(pos>=1.e-5){
1.265     brouard  4740:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4741:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4742:               }else if( nj==2){
                   4743:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4744:               }
                   4745:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4746:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4747:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4748:            } else{
                   4749:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4750:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4751:            }
1.240     brouard  4752:          }
1.265     brouard  4753:          pospropt[s1] +=posprop[s1];
                   4754:        } /* end loop s1 */
1.251     brouard  4755:        /* pospropt=0.; */
1.265     brouard  4756:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4757:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4758:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4759:              if(first==1){
1.265     brouard  4760:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4761:              }
1.265     brouard  4762:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4763:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4764:            }
1.265     brouard  4765:            if(s1!=0 && m!=0)
                   4766:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4767:          }
1.265     brouard  4768:        } /* end loop s1 */
1.251     brouard  4769:        posproptt=0.; 
1.265     brouard  4770:        for(s1=1; s1 <=nlstate; s1++){
                   4771:          posproptt += pospropt[s1];
1.251     brouard  4772:        }
                   4773:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4774:        fprintf(ficresphtm,"</tr>\n");
                   4775:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4776:          if(iage <= iagemax)
                   4777:            fprintf(ficresp,"\n");
1.240     brouard  4778:        }
1.251     brouard  4779:        if(first==1)
                   4780:          printf("Others in log...\n");
                   4781:        fprintf(ficlog,"\n");
                   4782:       } /* end loop age iage */
1.265     brouard  4783:       
1.251     brouard  4784:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4785:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4786:        if(posproptt < 1.e-5){
1.265     brouard  4787:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4788:        }else{
1.265     brouard  4789:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4790:        }
1.226     brouard  4791:       }
1.251     brouard  4792:       fprintf(ficresphtm,"</tr>\n");
                   4793:       fprintf(ficresphtm,"</table>\n");
                   4794:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4795:       if(posproptt < 1.e-5){
1.251     brouard  4796:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4797:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4798:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4799:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4800:        invalidvarcomb[j1]=1;
1.226     brouard  4801:       }else{
1.251     brouard  4802:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4803:        invalidvarcomb[j1]=0;
1.226     brouard  4804:       }
1.251     brouard  4805:       fprintf(ficresphtmfr,"</table>\n");
                   4806:       fprintf(ficlog,"\n");
                   4807:       if(j!=0){
                   4808:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4809:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4810:          for(k=1; k <=(nlstate+ndeath); k++){
                   4811:            if (k != i) {
1.265     brouard  4812:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4813:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4814:                  if(j1==1){ /* All dummy covariates to zero */
                   4815:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4816:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4817:                    printf("%d%d ",i,k);
                   4818:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4819:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4820:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4821:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4822:                  }
1.253     brouard  4823:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4824:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4825:                    x[iage]= (double)iage;
                   4826:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4827:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4828:                  }
1.268     brouard  4829:                  /* Some are not finite, but linreg will ignore these ages */
                   4830:                  no=0;
1.253     brouard  4831:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4832:                  pstart[s1]=b;
                   4833:                  pstart[s1-1]=a;
1.252     brouard  4834:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4835:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4836:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4837:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4838:                  printf("%d%d ",i,k);
                   4839:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4840:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4841:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4842:                  ;
                   4843:                }
                   4844:                /* printf("%12.7f )", param[i][jj][k]); */
                   4845:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4846:                s1++; 
1.251     brouard  4847:              } /* end jj */
                   4848:            } /* end k!= i */
                   4849:          } /* end k */
1.265     brouard  4850:        } /* end i, s1 */
1.251     brouard  4851:       } /* end j !=0 */
                   4852:     } /* end selected combination of covariate j1 */
                   4853:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4854:       printf("#Freqsummary: Starting values for the constants:\n");
                   4855:       fprintf(ficlog,"\n");
1.265     brouard  4856:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4857:        for(k=1; k <=(nlstate+ndeath); k++){
                   4858:          if (k != i) {
                   4859:            printf("%d%d ",i,k);
                   4860:            fprintf(ficlog,"%d%d ",i,k);
                   4861:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4862:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4863:              if(jj==1){ /* Age has to be done */
1.265     brouard  4864:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4865:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4866:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4867:              }
                   4868:              /* printf("%12.7f )", param[i][jj][k]); */
                   4869:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4870:              s1++; 
1.250     brouard  4871:            }
1.251     brouard  4872:            printf("\n");
                   4873:            fprintf(ficlog,"\n");
1.250     brouard  4874:          }
                   4875:        }
                   4876:       }
1.251     brouard  4877:       printf("#Freqsummary\n");
                   4878:       fprintf(ficlog,"\n");
1.265     brouard  4879:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4880:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4881:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4882:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4883:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4884:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4885:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4886:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4887:          /* } */
                   4888:        }
1.265     brouard  4889:       } /* end loop s1 */
1.251     brouard  4890:       
                   4891:       printf("\n");
                   4892:       fprintf(ficlog,"\n");
                   4893:     } /* end j=0 */
1.249     brouard  4894:   } /* end j */
1.252     brouard  4895: 
1.253     brouard  4896:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4897:     for(i=1, jk=1; i <=nlstate; i++){
                   4898:       for(j=1; j <=nlstate+ndeath; j++){
                   4899:        if(j!=i){
                   4900:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4901:          printf("%1d%1d",i,j);
                   4902:          fprintf(ficparo,"%1d%1d",i,j);
                   4903:          for(k=1; k<=ncovmodel;k++){
                   4904:            /*    printf(" %lf",param[i][j][k]); */
                   4905:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4906:            p[jk]=pstart[jk];
                   4907:            printf(" %f ",pstart[jk]);
                   4908:            fprintf(ficparo," %f ",pstart[jk]);
                   4909:            jk++;
                   4910:          }
                   4911:          printf("\n");
                   4912:          fprintf(ficparo,"\n");
                   4913:        }
                   4914:       }
                   4915:     }
                   4916:   } /* end mle=-2 */
1.226     brouard  4917:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4918:   
1.226     brouard  4919:   fclose(ficresp);
                   4920:   fclose(ficresphtm);
                   4921:   fclose(ficresphtmfr);
1.283   ! brouard  4922:   free_vector(idq,1,nqfveff);
1.226     brouard  4923:   free_vector(meanq,1,nqfveff);
                   4924:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4925:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4926:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4927:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4928:   free_vector(pospropt,1,nlstate);
                   4929:   free_vector(posprop,1,nlstate);
1.251     brouard  4930:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4931:   free_vector(pp,1,nlstate);
                   4932:   /* End of freqsummary */
                   4933: }
1.126     brouard  4934: 
1.268     brouard  4935: /* Simple linear regression */
                   4936: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4937: 
                   4938:   /* y=a+bx regression */
                   4939:   double   sumx = 0.0;                        /* sum of x                      */
                   4940:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4941:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4942:   double   sumy = 0.0;                        /* sum of y                      */
                   4943:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4944:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4945:   double yhat;
                   4946:   
                   4947:   double denom=0;
                   4948:   int i;
                   4949:   int ne=*no;
                   4950:   
                   4951:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4952:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4953:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4954:       continue;
                   4955:     }
                   4956:     ne=ne+1;
                   4957:     sumx  += x[i];       
                   4958:     sumx2 += x[i]*x[i];  
                   4959:     sumxy += x[i] * y[i];
                   4960:     sumy  += y[i];      
                   4961:     sumy2 += y[i]*y[i]; 
                   4962:     denom = (ne * sumx2 - sumx*sumx);
                   4963:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4964:   } 
                   4965:   
                   4966:   denom = (ne * sumx2 - sumx*sumx);
                   4967:   if (denom == 0) {
                   4968:     // vertical, slope m is infinity
                   4969:     *b = INFINITY;
                   4970:     *a = 0;
                   4971:     if (r) *r = 0;
                   4972:     return 1;
                   4973:   }
                   4974:   
                   4975:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4976:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4977:   if (r!=NULL) {
                   4978:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4979:       sqrt((sumx2 - sumx*sumx/ne) *
                   4980:           (sumy2 - sumy*sumy/ne));
                   4981:   }
                   4982:   *no=ne;
                   4983:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4984:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4985:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4986:       continue;
                   4987:     }
                   4988:     ne=ne+1;
                   4989:     yhat = y[i] - *a -*b* x[i];
                   4990:     sume2  += yhat * yhat ;       
                   4991:     
                   4992:     denom = (ne * sumx2 - sumx*sumx);
                   4993:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4994:   } 
                   4995:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4996:   *sa= *sb * sqrt(sumx2/ne);
                   4997:   
                   4998:   return 0; 
                   4999: }
                   5000: 
1.126     brouard  5001: /************ Prevalence ********************/
1.227     brouard  5002: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5003: {  
                   5004:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5005:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5006:      We still use firstpass and lastpass as another selection.
                   5007:   */
1.126     brouard  5008:  
1.227     brouard  5009:   int i, m, jk, j1, bool, z1,j, iv;
                   5010:   int mi; /* Effective wave */
                   5011:   int iage;
                   5012:   double agebegin, ageend;
                   5013: 
                   5014:   double **prop;
                   5015:   double posprop; 
                   5016:   double  y2; /* in fractional years */
                   5017:   int iagemin, iagemax;
                   5018:   int first; /** to stop verbosity which is redirected to log file */
                   5019: 
                   5020:   iagemin= (int) agemin;
                   5021:   iagemax= (int) agemax;
                   5022:   /*pp=vector(1,nlstate);*/
1.251     brouard  5023:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5024:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5025:   j1=0;
1.222     brouard  5026:   
1.227     brouard  5027:   /*j=cptcoveff;*/
                   5028:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5029:   
1.227     brouard  5030:   first=1;
                   5031:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5032:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5033:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5034:        prop[i][iage]=0.0;
                   5035:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5036:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5037:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5038:     
                   5039:     for (i=1; i<=imx; i++) { /* Each individual */
                   5040:       bool=1;
                   5041:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5042:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5043:        m=mw[mi][i];
                   5044:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5045:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5046:        for (z1=1; z1<=cptcoveff; z1++){
                   5047:          if( Fixed[Tmodelind[z1]]==1){
                   5048:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5049:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5050:              bool=0;
                   5051:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5052:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5053:              bool=0;
                   5054:            }
                   5055:        }
                   5056:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5057:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5058:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5059:          if(m >=firstpass && m <=lastpass){
                   5060:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5061:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5062:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5063:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5064:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5065:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5066:                exit(1);
                   5067:              }
                   5068:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5069:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5070:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5071:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5072:              } /* end valid statuses */ 
                   5073:            } /* end selection of dates */
                   5074:          } /* end selection of waves */
                   5075:        } /* end bool */
                   5076:       } /* end wave */
                   5077:     } /* end individual */
                   5078:     for(i=iagemin; i <= iagemax+3; i++){  
                   5079:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5080:        posprop += prop[jk][i]; 
                   5081:       } 
                   5082:       
                   5083:       for(jk=1; jk <=nlstate ; jk++){      
                   5084:        if( i <=  iagemax){ 
                   5085:          if(posprop>=1.e-5){ 
                   5086:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5087:          } else{
                   5088:            if(first==1){
                   5089:              first=0;
1.266     brouard  5090:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5091:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5092:            }else{
                   5093:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5094:            }
                   5095:          }
                   5096:        } 
                   5097:       }/* end jk */ 
                   5098:     }/* end i */ 
1.222     brouard  5099:      /*} *//* end i1 */
1.227     brouard  5100:   } /* end j1 */
1.222     brouard  5101:   
1.227     brouard  5102:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5103:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5104:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5105: }  /* End of prevalence */
1.126     brouard  5106: 
                   5107: /************* Waves Concatenation ***************/
                   5108: 
                   5109: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5110: {
                   5111:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5112:      Death is a valid wave (if date is known).
                   5113:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5114:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5115:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5116:   */
1.126     brouard  5117: 
1.224     brouard  5118:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5119:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5120:      double sum=0., jmean=0.;*/
1.224     brouard  5121:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5122:   int j, k=0,jk, ju, jl;
                   5123:   double sum=0.;
                   5124:   first=0;
1.214     brouard  5125:   firstwo=0;
1.217     brouard  5126:   firsthree=0;
1.218     brouard  5127:   firstfour=0;
1.164     brouard  5128:   jmin=100000;
1.126     brouard  5129:   jmax=-1;
                   5130:   jmean=0.;
1.224     brouard  5131: 
                   5132: /* Treating live states */
1.214     brouard  5133:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5134:     mi=0;  /* First valid wave */
1.227     brouard  5135:     mli=0; /* Last valid wave */
1.126     brouard  5136:     m=firstpass;
1.214     brouard  5137:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5138:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5139:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5140:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5141:        mw[++mi][i]=m;
                   5142:        mli=m;
1.224     brouard  5143:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5144:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5145:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5146:       }
1.227     brouard  5147:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5148: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5149:        break;
1.224     brouard  5150: #else
1.227     brouard  5151:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5152:          if(firsthree == 0){
1.262     brouard  5153:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5154:            firsthree=1;
                   5155:          }
1.262     brouard  5156:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5157:          mw[++mi][i]=m;
                   5158:          mli=m;
                   5159:        }
                   5160:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5161:          nbwarn++;
                   5162:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5163:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5164:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5165:          }
                   5166:          break;
                   5167:        }
                   5168:        break;
1.224     brouard  5169: #endif
1.227     brouard  5170:       }/* End m >= lastpass */
1.126     brouard  5171:     }/* end while */
1.224     brouard  5172: 
1.227     brouard  5173:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5174:     /* After last pass */
1.224     brouard  5175: /* Treating death states */
1.214     brouard  5176:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5177:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5178:       /* } */
1.126     brouard  5179:       mi++;    /* Death is another wave */
                   5180:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5181:       /* Only death is a correct wave */
1.126     brouard  5182:       mw[mi][i]=m;
1.257     brouard  5183:     } /* else not in a death state */
1.224     brouard  5184: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5185:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5186:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5187:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5188:          nbwarn++;
                   5189:          if(firstfiv==0){
                   5190:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5191:            firstfiv=1;
                   5192:          }else{
                   5193:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5194:          }
                   5195:        }else{ /* Death occured afer last wave potential bias */
                   5196:          nberr++;
                   5197:          if(firstwo==0){
1.257     brouard  5198:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5199:            firstwo=1;
                   5200:          }
1.257     brouard  5201:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5202:        }
1.257     brouard  5203:       }else{ /* if date of interview is unknown */
1.227     brouard  5204:        /* death is known but not confirmed by death status at any wave */
                   5205:        if(firstfour==0){
                   5206:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5207:          firstfour=1;
                   5208:        }
                   5209:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5210:       }
1.224     brouard  5211:     } /* end if date of death is known */
                   5212: #endif
                   5213:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5214:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5215:     if(mi==0){
                   5216:       nbwarn++;
                   5217:       if(first==0){
1.227     brouard  5218:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5219:        first=1;
1.126     brouard  5220:       }
                   5221:       if(first==1){
1.227     brouard  5222:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5223:       }
                   5224:     } /* end mi==0 */
                   5225:   } /* End individuals */
1.214     brouard  5226:   /* wav and mw are no more changed */
1.223     brouard  5227:        
1.214     brouard  5228:   
1.126     brouard  5229:   for(i=1; i<=imx; i++){
                   5230:     for(mi=1; mi<wav[i];mi++){
                   5231:       if (stepm <=0)
1.227     brouard  5232:        dh[mi][i]=1;
1.126     brouard  5233:       else{
1.260     brouard  5234:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5235:          if (agedc[i] < 2*AGESUP) {
                   5236:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5237:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5238:            else if(j<0){
                   5239:              nberr++;
                   5240:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5241:              j=1; /* Temporary Dangerous patch */
                   5242:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5243:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5244:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5245:            }
                   5246:            k=k+1;
                   5247:            if (j >= jmax){
                   5248:              jmax=j;
                   5249:              ijmax=i;
                   5250:            }
                   5251:            if (j <= jmin){
                   5252:              jmin=j;
                   5253:              ijmin=i;
                   5254:            }
                   5255:            sum=sum+j;
                   5256:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5257:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5258:          }
                   5259:        }
                   5260:        else{
                   5261:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5262: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5263:                                        
1.227     brouard  5264:          k=k+1;
                   5265:          if (j >= jmax) {
                   5266:            jmax=j;
                   5267:            ijmax=i;
                   5268:          }
                   5269:          else if (j <= jmin){
                   5270:            jmin=j;
                   5271:            ijmin=i;
                   5272:          }
                   5273:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5274:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5275:          if(j<0){
                   5276:            nberr++;
                   5277:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5278:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5279:          }
                   5280:          sum=sum+j;
                   5281:        }
                   5282:        jk= j/stepm;
                   5283:        jl= j -jk*stepm;
                   5284:        ju= j -(jk+1)*stepm;
                   5285:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5286:          if(jl==0){
                   5287:            dh[mi][i]=jk;
                   5288:            bh[mi][i]=0;
                   5289:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5290:                  * to avoid the price of an extra matrix product in likelihood */
                   5291:            dh[mi][i]=jk+1;
                   5292:            bh[mi][i]=ju;
                   5293:          }
                   5294:        }else{
                   5295:          if(jl <= -ju){
                   5296:            dh[mi][i]=jk;
                   5297:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5298:                                 * is higher than the multiple of stepm and negative otherwise.
                   5299:                                 */
                   5300:          }
                   5301:          else{
                   5302:            dh[mi][i]=jk+1;
                   5303:            bh[mi][i]=ju;
                   5304:          }
                   5305:          if(dh[mi][i]==0){
                   5306:            dh[mi][i]=1; /* At least one step */
                   5307:            bh[mi][i]=ju; /* At least one step */
                   5308:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5309:          }
                   5310:        } /* end if mle */
1.126     brouard  5311:       }
                   5312:     } /* end wave */
                   5313:   }
                   5314:   jmean=sum/k;
                   5315:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5316:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5317: }
1.126     brouard  5318: 
                   5319: /*********** Tricode ****************************/
1.220     brouard  5320:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5321:  {
                   5322:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5323:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5324:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5325:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5326:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5327:     */
1.130     brouard  5328: 
1.242     brouard  5329:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5330:    int modmaxcovj=0; /* Modality max of covariates j */
                   5331:    int cptcode=0; /* Modality max of covariates j */
                   5332:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5333: 
                   5334: 
1.242     brouard  5335:    /* cptcoveff=0;  */
                   5336:    /* *cptcov=0; */
1.126     brouard  5337:  
1.242     brouard  5338:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5339: 
1.242     brouard  5340:    /* Loop on covariates without age and products and no quantitative variable */
                   5341:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5342:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5343:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5344:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5345:        switch(Fixed[k]) {
                   5346:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5347:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5348:           ij=(int)(covar[Tvar[k]][i]);
                   5349:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5350:            * If product of Vn*Vm, still boolean *:
                   5351:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5352:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5353:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5354:              modality of the nth covariate of individual i. */
                   5355:           if (ij > modmaxcovj)
                   5356:             modmaxcovj=ij; 
                   5357:           else if (ij < modmincovj) 
                   5358:             modmincovj=ij; 
                   5359:           if ((ij < -1) && (ij > NCOVMAX)){
                   5360:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5361:             exit(1);
                   5362:           }else
                   5363:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5364:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5365:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5366:           /* getting the maximum value of the modality of the covariate
                   5367:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5368:              female ies 1, then modmaxcovj=1.
                   5369:           */
                   5370:         } /* end for loop on individuals i */
                   5371:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5372:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5373:         cptcode=modmaxcovj;
                   5374:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5375:         /*for (i=0; i<=cptcode; i++) {*/
                   5376:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5377:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5378:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5379:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5380:             if( j != -1){
                   5381:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5382:                                  covariate for which somebody answered excluding 
                   5383:                                  undefined. Usually 2: 0 and 1. */
                   5384:             }
                   5385:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5386:                                     covariate for which somebody answered including 
                   5387:                                     undefined. Usually 3: -1, 0 and 1. */
                   5388:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5389:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5390:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5391:                        
1.242     brouard  5392:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5393:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5394:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5395:         /* modmincovj=3; modmaxcovj = 7; */
                   5396:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5397:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5398:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5399:         /* nbcode[Tvar[j]][ij]=k; */
                   5400:         /* nbcode[Tvar[j]][1]=0; */
                   5401:         /* nbcode[Tvar[j]][2]=1; */
                   5402:         /* nbcode[Tvar[j]][3]=2; */
                   5403:         /* To be continued (not working yet). */
                   5404:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5405:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5406:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5407:             break;
                   5408:           }
                   5409:           ij++;
                   5410:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5411:           cptcode = ij; /* New max modality for covar j */
                   5412:         } /* end of loop on modality i=-1 to 1 or more */
                   5413:         break;
                   5414:        case 1: /* Testing on varying covariate, could be simple and
                   5415:                * should look at waves or product of fixed *
                   5416:                * varying. No time to test -1, assuming 0 and 1 only */
                   5417:         ij=0;
                   5418:         for(i=0; i<=1;i++){
                   5419:           nbcode[Tvar[k]][++ij]=i;
                   5420:         }
                   5421:         break;
                   5422:        default:
                   5423:         break;
                   5424:        } /* end switch */
                   5425:      } /* end dummy test */
                   5426:     
                   5427:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5428:      /*        /\*recode from 0 *\/ */
                   5429:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5430:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5431:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5432:      /*        } */
                   5433:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5434:      /*        if (ij > ncodemax[j]) { */
                   5435:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5436:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5437:      /*          break; */
                   5438:      /*        } */
                   5439:      /*   }  /\* end of loop on modality k *\/ */
                   5440:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5441:   
                   5442:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5443:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5444:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5445:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5446:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5447:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5448:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5449:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5450:   
                   5451:    ij=0;
                   5452:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5453:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5454:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5455:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5456:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5457:        /* If product not in single variable we don't print results */
                   5458:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5459:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5460:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5461:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5462:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5463:        if(Fixed[k]!=0)
                   5464:         anyvaryingduminmodel=1;
                   5465:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5466:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5467:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5468:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5469:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5470:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5471:      } 
                   5472:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5473:    /* ij--; */
                   5474:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5475:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5476:                * because they can be excluded from the model and real
                   5477:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5478:    for(j=ij+1; j<= cptcovt; j++){
                   5479:      Tvaraff[j]=0;
                   5480:      Tmodelind[j]=0;
                   5481:    }
                   5482:    for(j=ntveff+1; j<= cptcovt; j++){
                   5483:      TmodelInvind[j]=0;
                   5484:    }
                   5485:    /* To be sorted */
                   5486:    ;
                   5487:  }
1.126     brouard  5488: 
1.145     brouard  5489: 
1.126     brouard  5490: /*********** Health Expectancies ****************/
                   5491: 
1.235     brouard  5492:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5493: 
                   5494: {
                   5495:   /* Health expectancies, no variances */
1.164     brouard  5496:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5497:   int nhstepma, nstepma; /* Decreasing with age */
                   5498:   double age, agelim, hf;
                   5499:   double ***p3mat;
                   5500:   double eip;
                   5501: 
1.238     brouard  5502:   /* pstamp(ficreseij); */
1.126     brouard  5503:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5504:   fprintf(ficreseij,"# Age");
                   5505:   for(i=1; i<=nlstate;i++){
                   5506:     for(j=1; j<=nlstate;j++){
                   5507:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5508:     }
                   5509:     fprintf(ficreseij," e%1d. ",i);
                   5510:   }
                   5511:   fprintf(ficreseij,"\n");
                   5512: 
                   5513:   
                   5514:   if(estepm < stepm){
                   5515:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5516:   }
                   5517:   else  hstepm=estepm;   
                   5518:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5519:    * This is mainly to measure the difference between two models: for example
                   5520:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5521:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5522:    * progression in between and thus overestimating or underestimating according
                   5523:    * to the curvature of the survival function. If, for the same date, we 
                   5524:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5525:    * to compare the new estimate of Life expectancy with the same linear 
                   5526:    * hypothesis. A more precise result, taking into account a more precise
                   5527:    * curvature will be obtained if estepm is as small as stepm. */
                   5528: 
                   5529:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5530:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5531:      nhstepm is the number of hstepm from age to agelim 
                   5532:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5533:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5534:      and note for a fixed period like estepm months */
                   5535:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5536:      survival function given by stepm (the optimization length). Unfortunately it
                   5537:      means that if the survival funtion is printed only each two years of age and if
                   5538:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5539:      results. So we changed our mind and took the option of the best precision.
                   5540:   */
                   5541:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5542: 
                   5543:   agelim=AGESUP;
                   5544:   /* If stepm=6 months */
                   5545:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5546:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5547:     
                   5548: /* nhstepm age range expressed in number of stepm */
                   5549:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5550:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5551:   /* if (stepm >= YEARM) hstepm=1;*/
                   5552:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5553:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5554: 
                   5555:   for (age=bage; age<=fage; age ++){ 
                   5556:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5557:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5558:     /* if (stepm >= YEARM) hstepm=1;*/
                   5559:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5560: 
                   5561:     /* If stepm=6 months */
                   5562:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5563:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5564:     
1.235     brouard  5565:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5566:     
                   5567:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5568:     
                   5569:     printf("%d|",(int)age);fflush(stdout);
                   5570:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5571:     
                   5572:     /* Computing expectancies */
                   5573:     for(i=1; i<=nlstate;i++)
                   5574:       for(j=1; j<=nlstate;j++)
                   5575:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5576:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5577:          
                   5578:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5579: 
                   5580:        }
                   5581: 
                   5582:     fprintf(ficreseij,"%3.0f",age );
                   5583:     for(i=1; i<=nlstate;i++){
                   5584:       eip=0;
                   5585:       for(j=1; j<=nlstate;j++){
                   5586:        eip +=eij[i][j][(int)age];
                   5587:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5588:       }
                   5589:       fprintf(ficreseij,"%9.4f", eip );
                   5590:     }
                   5591:     fprintf(ficreseij,"\n");
                   5592:     
                   5593:   }
                   5594:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5595:   printf("\n");
                   5596:   fprintf(ficlog,"\n");
                   5597:   
                   5598: }
                   5599: 
1.235     brouard  5600:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5601: 
                   5602: {
                   5603:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5604:      to initial status i, ei. .
1.126     brouard  5605:   */
                   5606:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5607:   int nhstepma, nstepma; /* Decreasing with age */
                   5608:   double age, agelim, hf;
                   5609:   double ***p3matp, ***p3matm, ***varhe;
                   5610:   double **dnewm,**doldm;
                   5611:   double *xp, *xm;
                   5612:   double **gp, **gm;
                   5613:   double ***gradg, ***trgradg;
                   5614:   int theta;
                   5615: 
                   5616:   double eip, vip;
                   5617: 
                   5618:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5619:   xp=vector(1,npar);
                   5620:   xm=vector(1,npar);
                   5621:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5622:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5623:   
                   5624:   pstamp(ficresstdeij);
                   5625:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5626:   fprintf(ficresstdeij,"# Age");
                   5627:   for(i=1; i<=nlstate;i++){
                   5628:     for(j=1; j<=nlstate;j++)
                   5629:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5630:     fprintf(ficresstdeij," e%1d. ",i);
                   5631:   }
                   5632:   fprintf(ficresstdeij,"\n");
                   5633: 
                   5634:   pstamp(ficrescveij);
                   5635:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5636:   fprintf(ficrescveij,"# Age");
                   5637:   for(i=1; i<=nlstate;i++)
                   5638:     for(j=1; j<=nlstate;j++){
                   5639:       cptj= (j-1)*nlstate+i;
                   5640:       for(i2=1; i2<=nlstate;i2++)
                   5641:        for(j2=1; j2<=nlstate;j2++){
                   5642:          cptj2= (j2-1)*nlstate+i2;
                   5643:          if(cptj2 <= cptj)
                   5644:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5645:        }
                   5646:     }
                   5647:   fprintf(ficrescveij,"\n");
                   5648:   
                   5649:   if(estepm < stepm){
                   5650:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5651:   }
                   5652:   else  hstepm=estepm;   
                   5653:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5654:    * This is mainly to measure the difference between two models: for example
                   5655:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5656:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5657:    * progression in between and thus overestimating or underestimating according
                   5658:    * to the curvature of the survival function. If, for the same date, we 
                   5659:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5660:    * to compare the new estimate of Life expectancy with the same linear 
                   5661:    * hypothesis. A more precise result, taking into account a more precise
                   5662:    * curvature will be obtained if estepm is as small as stepm. */
                   5663: 
                   5664:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5665:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5666:      nhstepm is the number of hstepm from age to agelim 
                   5667:      nstepm is the number of stepm from age to agelin. 
                   5668:      Look at hpijx to understand the reason of that which relies in memory size
                   5669:      and note for a fixed period like estepm months */
                   5670:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5671:      survival function given by stepm (the optimization length). Unfortunately it
                   5672:      means that if the survival funtion is printed only each two years of age and if
                   5673:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5674:      results. So we changed our mind and took the option of the best precision.
                   5675:   */
                   5676:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5677: 
                   5678:   /* If stepm=6 months */
                   5679:   /* nhstepm age range expressed in number of stepm */
                   5680:   agelim=AGESUP;
                   5681:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5682:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5683:   /* if (stepm >= YEARM) hstepm=1;*/
                   5684:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5685:   
                   5686:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5687:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5688:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5689:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5690:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5691:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5692: 
                   5693:   for (age=bage; age<=fage; age ++){ 
                   5694:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5695:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5696:     /* if (stepm >= YEARM) hstepm=1;*/
                   5697:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5698:                
1.126     brouard  5699:     /* If stepm=6 months */
                   5700:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5701:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5702:     
                   5703:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5704:                
1.126     brouard  5705:     /* Computing  Variances of health expectancies */
                   5706:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5707:        decrease memory allocation */
                   5708:     for(theta=1; theta <=npar; theta++){
                   5709:       for(i=1; i<=npar; i++){ 
1.222     brouard  5710:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5711:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5712:       }
1.235     brouard  5713:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5714:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5715:                        
1.126     brouard  5716:       for(j=1; j<= nlstate; j++){
1.222     brouard  5717:        for(i=1; i<=nlstate; i++){
                   5718:          for(h=0; h<=nhstepm-1; h++){
                   5719:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5720:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5721:          }
                   5722:        }
1.126     brouard  5723:       }
1.218     brouard  5724:                        
1.126     brouard  5725:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5726:        for(h=0; h<=nhstepm-1; h++){
                   5727:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5728:        }
1.126     brouard  5729:     }/* End theta */
                   5730:     
                   5731:     
                   5732:     for(h=0; h<=nhstepm-1; h++)
                   5733:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5734:        for(theta=1; theta <=npar; theta++)
                   5735:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5736:     
1.218     brouard  5737:                
1.222     brouard  5738:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5739:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5740:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5741:                
1.222     brouard  5742:     printf("%d|",(int)age);fflush(stdout);
                   5743:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5744:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5745:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5746:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5747:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5748:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5749:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5750:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5751:       }
                   5752:     }
1.218     brouard  5753:                
1.126     brouard  5754:     /* Computing expectancies */
1.235     brouard  5755:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5756:     for(i=1; i<=nlstate;i++)
                   5757:       for(j=1; j<=nlstate;j++)
1.222     brouard  5758:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5759:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5760:                                        
1.222     brouard  5761:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5762:                                        
1.222     brouard  5763:        }
1.269     brouard  5764: 
                   5765:     /* Standard deviation of expectancies ij */                
1.126     brouard  5766:     fprintf(ficresstdeij,"%3.0f",age );
                   5767:     for(i=1; i<=nlstate;i++){
                   5768:       eip=0.;
                   5769:       vip=0.;
                   5770:       for(j=1; j<=nlstate;j++){
1.222     brouard  5771:        eip += eij[i][j][(int)age];
                   5772:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5773:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5774:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5775:       }
                   5776:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5777:     }
                   5778:     fprintf(ficresstdeij,"\n");
1.218     brouard  5779:                
1.269     brouard  5780:     /* Variance of expectancies ij */          
1.126     brouard  5781:     fprintf(ficrescveij,"%3.0f",age );
                   5782:     for(i=1; i<=nlstate;i++)
                   5783:       for(j=1; j<=nlstate;j++){
1.222     brouard  5784:        cptj= (j-1)*nlstate+i;
                   5785:        for(i2=1; i2<=nlstate;i2++)
                   5786:          for(j2=1; j2<=nlstate;j2++){
                   5787:            cptj2= (j2-1)*nlstate+i2;
                   5788:            if(cptj2 <= cptj)
                   5789:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5790:          }
1.126     brouard  5791:       }
                   5792:     fprintf(ficrescveij,"\n");
1.218     brouard  5793:                
1.126     brouard  5794:   }
                   5795:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5796:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5797:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5798:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5799:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5800:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5801:   printf("\n");
                   5802:   fprintf(ficlog,"\n");
1.218     brouard  5803:        
1.126     brouard  5804:   free_vector(xm,1,npar);
                   5805:   free_vector(xp,1,npar);
                   5806:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5807:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5808:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5809: }
1.218     brouard  5810:  
1.126     brouard  5811: /************ Variance ******************/
1.235     brouard  5812:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5813:  {
1.279     brouard  5814:    /** Variance of health expectancies 
                   5815:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5816:     * double **newm;
                   5817:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5818:     */
1.218     brouard  5819:   
                   5820:    /* int movingaverage(); */
                   5821:    double **dnewm,**doldm;
                   5822:    double **dnewmp,**doldmp;
                   5823:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5824:    int k;
                   5825:    double *xp;
1.279     brouard  5826:    double **gp, **gm;  /**< for var eij */
                   5827:    double ***gradg, ***trgradg; /**< for var eij */
                   5828:    double **gradgp, **trgradgp; /**< for var p point j */
                   5829:    double *gpp, *gmp; /**< for var p point j */
                   5830:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5831:    double ***p3mat;
                   5832:    double age,agelim, hf;
                   5833:    /* double ***mobaverage; */
                   5834:    int theta;
                   5835:    char digit[4];
                   5836:    char digitp[25];
                   5837: 
                   5838:    char fileresprobmorprev[FILENAMELENGTH];
                   5839: 
                   5840:    if(popbased==1){
                   5841:      if(mobilav!=0)
                   5842:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5843:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5844:    }
                   5845:    else 
                   5846:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5847: 
1.218     brouard  5848:    /* if (mobilav!=0) { */
                   5849:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5850:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5851:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5852:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5853:    /*   } */
                   5854:    /* } */
                   5855: 
                   5856:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5857:    sprintf(digit,"%-d",ij);
                   5858:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5859:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5860:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5861:    strcat(fileresprobmorprev,fileresu);
                   5862:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5863:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5864:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5865:    }
                   5866:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5867:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5868:    pstamp(ficresprobmorprev);
                   5869:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5870:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5871:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5872:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5873:    }
                   5874:    for(j=1;j<=cptcoveff;j++) 
                   5875:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5876:    fprintf(ficresprobmorprev,"\n");
                   5877: 
1.218     brouard  5878:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5879:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5880:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5881:      for(i=1; i<=nlstate;i++)
                   5882:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5883:    }  
                   5884:    fprintf(ficresprobmorprev,"\n");
                   5885:   
                   5886:    fprintf(ficgp,"\n# Routine varevsij");
                   5887:    fprintf(ficgp,"\nunset title \n");
                   5888:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5889:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5890:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5891: 
1.218     brouard  5892:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5893:    pstamp(ficresvij);
                   5894:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5895:    if(popbased==1)
                   5896:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5897:    else
                   5898:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5899:    fprintf(ficresvij,"# Age");
                   5900:    for(i=1; i<=nlstate;i++)
                   5901:      for(j=1; j<=nlstate;j++)
                   5902:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5903:    fprintf(ficresvij,"\n");
                   5904: 
                   5905:    xp=vector(1,npar);
                   5906:    dnewm=matrix(1,nlstate,1,npar);
                   5907:    doldm=matrix(1,nlstate,1,nlstate);
                   5908:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5909:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5910: 
                   5911:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5912:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5913:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5914:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5915:   
1.218     brouard  5916:    if(estepm < stepm){
                   5917:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5918:    }
                   5919:    else  hstepm=estepm;   
                   5920:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5921:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5922:       nhstepm is the number of hstepm from age to agelim 
                   5923:       nstepm is the number of stepm from age to agelim. 
                   5924:       Look at function hpijx to understand why because of memory size limitations, 
                   5925:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5926:       survival function given by stepm (the optimization length). Unfortunately it
                   5927:       means that if the survival funtion is printed every two years of age and if
                   5928:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5929:       results. So we changed our mind and took the option of the best precision.
                   5930:    */
                   5931:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5932:    agelim = AGESUP;
                   5933:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5934:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5935:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5936:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5937:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5938:      gp=matrix(0,nhstepm,1,nlstate);
                   5939:      gm=matrix(0,nhstepm,1,nlstate);
                   5940:                
                   5941:                
                   5942:      for(theta=1; theta <=npar; theta++){
                   5943:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5944:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5945:        }
1.279     brouard  5946:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5947:        * returns into prlim .
                   5948:        */              
1.242     brouard  5949:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5950: 
                   5951:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5952:        if (popbased==1) {
                   5953:         if(mobilav ==0){
                   5954:           for(i=1; i<=nlstate;i++)
                   5955:             prlim[i][i]=probs[(int)age][i][ij];
                   5956:         }else{ /* mobilav */ 
                   5957:           for(i=1; i<=nlstate;i++)
                   5958:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5959:         }
                   5960:        }
1.279     brouard  5961:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5962:        */                      
                   5963:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   5964:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   5965:        * at horizon h in state j including mortality.
                   5966:        */
1.218     brouard  5967:        for(j=1; j<= nlstate; j++){
                   5968:         for(h=0; h<=nhstepm; h++){
                   5969:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5970:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5971:         }
                   5972:        }
1.279     brouard  5973:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  5974:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  5975:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  5976:        */
                   5977:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5978:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5979:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  5980:        }
                   5981:        
                   5982:        /* Again with minus shift */
1.218     brouard  5983:                        
                   5984:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5985:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5986:                        
1.242     brouard  5987:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5988:                        
                   5989:        if (popbased==1) {
                   5990:         if(mobilav ==0){
                   5991:           for(i=1; i<=nlstate;i++)
                   5992:             prlim[i][i]=probs[(int)age][i][ij];
                   5993:         }else{ /* mobilav */ 
                   5994:           for(i=1; i<=nlstate;i++)
                   5995:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5996:         }
                   5997:        }
                   5998:                        
1.235     brouard  5999:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6000:                        
                   6001:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6002:         for(h=0; h<=nhstepm; h++){
                   6003:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6004:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6005:         }
                   6006:        }
                   6007:        /* This for computing probability of death (h=1 means
                   6008:          computed over hstepm matrices product = hstepm*stepm months) 
                   6009:          as a weighted average of prlim.
                   6010:        */
                   6011:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6012:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6013:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6014:        }    
1.279     brouard  6015:        /* end shifting computations */
                   6016: 
                   6017:        /**< Computing gradient matrix at horizon h 
                   6018:        */
1.218     brouard  6019:        for(j=1; j<= nlstate; j++) /* vareij */
                   6020:         for(h=0; h<=nhstepm; h++){
                   6021:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6022:         }
1.279     brouard  6023:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6024:        */
                   6025:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6026:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6027:        }
                   6028:                        
                   6029:      } /* End theta */
1.279     brouard  6030:      
                   6031:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6032:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6033:                
                   6034:      for(h=0; h<=nhstepm; h++) /* veij */
                   6035:        for(j=1; j<=nlstate;j++)
                   6036:         for(theta=1; theta <=npar; theta++)
                   6037:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6038:                
                   6039:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6040:        for(theta=1; theta <=npar; theta++)
                   6041:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6042:      /**< as well as its transposed matrix 
                   6043:       */               
1.218     brouard  6044:                
                   6045:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6046:      for(i=1;i<=nlstate;i++)
                   6047:        for(j=1;j<=nlstate;j++)
                   6048:         vareij[i][j][(int)age] =0.;
1.279     brouard  6049: 
                   6050:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6051:       * and k (nhstepm) formula 15 of article
                   6052:       * Lievre-Brouard-Heathcote
                   6053:       */
                   6054:      
1.218     brouard  6055:      for(h=0;h<=nhstepm;h++){
                   6056:        for(k=0;k<=nhstepm;k++){
                   6057:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6058:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6059:         for(i=1;i<=nlstate;i++)
                   6060:           for(j=1;j<=nlstate;j++)
                   6061:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6062:        }
                   6063:      }
                   6064:                
1.279     brouard  6065:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6066:       * p.j overall mortality formula 49 but computed directly because
                   6067:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6068:       * wix is independent of theta.
                   6069:       */
1.218     brouard  6070:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6071:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6072:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6073:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6074:         varppt[j][i]=doldmp[j][i];
                   6075:      /* end ppptj */
                   6076:      /*  x centered again */
                   6077:                
1.242     brouard  6078:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6079:                
                   6080:      if (popbased==1) {
                   6081:        if(mobilav ==0){
                   6082:         for(i=1; i<=nlstate;i++)
                   6083:           prlim[i][i]=probs[(int)age][i][ij];
                   6084:        }else{ /* mobilav */ 
                   6085:         for(i=1; i<=nlstate;i++)
                   6086:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6087:        }
                   6088:      }
                   6089:                
                   6090:      /* This for computing probability of death (h=1 means
                   6091:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6092:        as a weighted average of prlim.
                   6093:      */
1.235     brouard  6094:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6095:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6096:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6097:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6098:      }    
                   6099:      /* end probability of death */
                   6100:                
                   6101:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6102:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6103:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6104:        for(i=1; i<=nlstate;i++){
                   6105:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6106:        }
                   6107:      } 
                   6108:      fprintf(ficresprobmorprev,"\n");
                   6109:                
                   6110:      fprintf(ficresvij,"%.0f ",age );
                   6111:      for(i=1; i<=nlstate;i++)
                   6112:        for(j=1; j<=nlstate;j++){
                   6113:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6114:        }
                   6115:      fprintf(ficresvij,"\n");
                   6116:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6117:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6118:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6119:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6120:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6121:    } /* End age */
                   6122:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6123:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6124:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6125:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6126:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6127:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6128:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6129:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6130:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6131:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6132:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6133:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6134:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6135:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6136:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6137:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6138:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6139:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6140:     */
1.218     brouard  6141:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6142:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6143: 
1.218     brouard  6144:    free_vector(xp,1,npar);
                   6145:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6146:    free_matrix(dnewm,1,nlstate,1,npar);
                   6147:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6148:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6149:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6150:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6151:    fclose(ficresprobmorprev);
                   6152:    fflush(ficgp);
                   6153:    fflush(fichtm); 
                   6154:  }  /* end varevsij */
1.126     brouard  6155: 
                   6156: /************ Variance of prevlim ******************/
1.269     brouard  6157:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6158: {
1.205     brouard  6159:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6160:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6161: 
1.268     brouard  6162:   double **dnewmpar,**doldm;
1.126     brouard  6163:   int i, j, nhstepm, hstepm;
                   6164:   double *xp;
                   6165:   double *gp, *gm;
                   6166:   double **gradg, **trgradg;
1.208     brouard  6167:   double **mgm, **mgp;
1.126     brouard  6168:   double age,agelim;
                   6169:   int theta;
                   6170:   
                   6171:   pstamp(ficresvpl);
                   6172:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6173:   fprintf(ficresvpl,"# Age ");
                   6174:   if(nresult >=1)
                   6175:     fprintf(ficresvpl," Result# ");
1.126     brouard  6176:   for(i=1; i<=nlstate;i++)
                   6177:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6178:   fprintf(ficresvpl,"\n");
                   6179: 
                   6180:   xp=vector(1,npar);
1.268     brouard  6181:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6182:   doldm=matrix(1,nlstate,1,nlstate);
                   6183:   
                   6184:   hstepm=1*YEARM; /* Every year of age */
                   6185:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6186:   agelim = AGESUP;
                   6187:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6188:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6189:     if (stepm >= YEARM) hstepm=1;
                   6190:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6191:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6192:     mgp=matrix(1,npar,1,nlstate);
                   6193:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6194:     gp=vector(1,nlstate);
                   6195:     gm=vector(1,nlstate);
                   6196: 
                   6197:     for(theta=1; theta <=npar; theta++){
                   6198:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6199:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6200:       }
1.209     brouard  6201:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6202:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6203:       else
1.235     brouard  6204:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6205:       for(i=1;i<=nlstate;i++){
1.126     brouard  6206:        gp[i] = prlim[i][i];
1.208     brouard  6207:        mgp[theta][i] = prlim[i][i];
                   6208:       }
1.126     brouard  6209:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6210:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6211:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6212:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6213:       else
1.235     brouard  6214:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6215:       for(i=1;i<=nlstate;i++){
1.126     brouard  6216:        gm[i] = prlim[i][i];
1.208     brouard  6217:        mgm[theta][i] = prlim[i][i];
                   6218:       }
1.126     brouard  6219:       for(i=1;i<=nlstate;i++)
                   6220:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6221:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6222:     } /* End theta */
                   6223: 
                   6224:     trgradg =matrix(1,nlstate,1,npar);
                   6225: 
                   6226:     for(j=1; j<=nlstate;j++)
                   6227:       for(theta=1; theta <=npar; theta++)
                   6228:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6229:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6230:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6231:     /*   for(j=1; j<=nlstate;j++){ */
                   6232:     /*         printf(" %d ",j); */
                   6233:     /*         for(theta=1; theta <=npar; theta++) */
                   6234:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6235:     /*         printf("\n "); */
                   6236:     /*   } */
                   6237:     /* } */
                   6238:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6239:     /*   printf("\n gradg %d ",(int)age); */
                   6240:     /*   for(j=1; j<=nlstate;j++){ */
                   6241:     /*         printf("%d ",j); */
                   6242:     /*         for(theta=1; theta <=npar; theta++) */
                   6243:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6244:     /*         printf("\n "); */
                   6245:     /*   } */
                   6246:     /* } */
1.126     brouard  6247: 
                   6248:     for(i=1;i<=nlstate;i++)
                   6249:       varpl[i][(int)age] =0.;
1.209     brouard  6250:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6251:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6252:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6253:     }else{
1.268     brouard  6254:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6255:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6256:     }
1.126     brouard  6257:     for(i=1;i<=nlstate;i++)
                   6258:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6259: 
                   6260:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6261:     if(nresult >=1)
                   6262:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6263:     for(i=1; i<=nlstate;i++)
                   6264:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6265:     fprintf(ficresvpl,"\n");
                   6266:     free_vector(gp,1,nlstate);
                   6267:     free_vector(gm,1,nlstate);
1.208     brouard  6268:     free_matrix(mgm,1,npar,1,nlstate);
                   6269:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6270:     free_matrix(gradg,1,npar,1,nlstate);
                   6271:     free_matrix(trgradg,1,nlstate,1,npar);
                   6272:   } /* End age */
                   6273: 
                   6274:   free_vector(xp,1,npar);
                   6275:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6276:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6277: 
                   6278: }
                   6279: 
                   6280: 
                   6281: /************ Variance of backprevalence limit ******************/
1.269     brouard  6282:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6283: {
                   6284:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6285:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6286: 
                   6287:   double **dnewmpar,**doldm;
                   6288:   int i, j, nhstepm, hstepm;
                   6289:   double *xp;
                   6290:   double *gp, *gm;
                   6291:   double **gradg, **trgradg;
                   6292:   double **mgm, **mgp;
                   6293:   double age,agelim;
                   6294:   int theta;
                   6295:   
                   6296:   pstamp(ficresvbl);
                   6297:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6298:   fprintf(ficresvbl,"# Age ");
                   6299:   if(nresult >=1)
                   6300:     fprintf(ficresvbl," Result# ");
                   6301:   for(i=1; i<=nlstate;i++)
                   6302:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6303:   fprintf(ficresvbl,"\n");
                   6304: 
                   6305:   xp=vector(1,npar);
                   6306:   dnewmpar=matrix(1,nlstate,1,npar);
                   6307:   doldm=matrix(1,nlstate,1,nlstate);
                   6308:   
                   6309:   hstepm=1*YEARM; /* Every year of age */
                   6310:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6311:   agelim = AGEINF;
                   6312:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6313:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6314:     if (stepm >= YEARM) hstepm=1;
                   6315:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6316:     gradg=matrix(1,npar,1,nlstate);
                   6317:     mgp=matrix(1,npar,1,nlstate);
                   6318:     mgm=matrix(1,npar,1,nlstate);
                   6319:     gp=vector(1,nlstate);
                   6320:     gm=vector(1,nlstate);
                   6321: 
                   6322:     for(theta=1; theta <=npar; theta++){
                   6323:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6324:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6325:       }
                   6326:       if(mobilavproj > 0 )
                   6327:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6328:       else
                   6329:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6330:       for(i=1;i<=nlstate;i++){
                   6331:        gp[i] = bprlim[i][i];
                   6332:        mgp[theta][i] = bprlim[i][i];
                   6333:       }
                   6334:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6335:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6336:        if(mobilavproj > 0 )
                   6337:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6338:        else
                   6339:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6340:       for(i=1;i<=nlstate;i++){
                   6341:        gm[i] = bprlim[i][i];
                   6342:        mgm[theta][i] = bprlim[i][i];
                   6343:       }
                   6344:       for(i=1;i<=nlstate;i++)
                   6345:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6346:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6347:     } /* End theta */
                   6348: 
                   6349:     trgradg =matrix(1,nlstate,1,npar);
                   6350: 
                   6351:     for(j=1; j<=nlstate;j++)
                   6352:       for(theta=1; theta <=npar; theta++)
                   6353:        trgradg[j][theta]=gradg[theta][j];
                   6354:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6355:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6356:     /*   for(j=1; j<=nlstate;j++){ */
                   6357:     /*         printf(" %d ",j); */
                   6358:     /*         for(theta=1; theta <=npar; theta++) */
                   6359:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6360:     /*         printf("\n "); */
                   6361:     /*   } */
                   6362:     /* } */
                   6363:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6364:     /*   printf("\n gradg %d ",(int)age); */
                   6365:     /*   for(j=1; j<=nlstate;j++){ */
                   6366:     /*         printf("%d ",j); */
                   6367:     /*         for(theta=1; theta <=npar; theta++) */
                   6368:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6369:     /*         printf("\n "); */
                   6370:     /*   } */
                   6371:     /* } */
                   6372: 
                   6373:     for(i=1;i<=nlstate;i++)
                   6374:       varbpl[i][(int)age] =0.;
                   6375:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6376:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6377:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6378:     }else{
                   6379:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6380:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6381:     }
                   6382:     for(i=1;i<=nlstate;i++)
                   6383:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6384: 
                   6385:     fprintf(ficresvbl,"%.0f ",age );
                   6386:     if(nresult >=1)
                   6387:       fprintf(ficresvbl,"%d ",nres );
                   6388:     for(i=1; i<=nlstate;i++)
                   6389:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6390:     fprintf(ficresvbl,"\n");
                   6391:     free_vector(gp,1,nlstate);
                   6392:     free_vector(gm,1,nlstate);
                   6393:     free_matrix(mgm,1,npar,1,nlstate);
                   6394:     free_matrix(mgp,1,npar,1,nlstate);
                   6395:     free_matrix(gradg,1,npar,1,nlstate);
                   6396:     free_matrix(trgradg,1,nlstate,1,npar);
                   6397:   } /* End age */
                   6398: 
                   6399:   free_vector(xp,1,npar);
                   6400:   free_matrix(doldm,1,nlstate,1,npar);
                   6401:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6402: 
                   6403: }
                   6404: 
                   6405: /************ Variance of one-step probabilities  ******************/
                   6406: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6407:  {
                   6408:    int i, j=0,  k1, l1, tj;
                   6409:    int k2, l2, j1,  z1;
                   6410:    int k=0, l;
                   6411:    int first=1, first1, first2;
                   6412:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6413:    double **dnewm,**doldm;
                   6414:    double *xp;
                   6415:    double *gp, *gm;
                   6416:    double **gradg, **trgradg;
                   6417:    double **mu;
                   6418:    double age, cov[NCOVMAX+1];
                   6419:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6420:    int theta;
                   6421:    char fileresprob[FILENAMELENGTH];
                   6422:    char fileresprobcov[FILENAMELENGTH];
                   6423:    char fileresprobcor[FILENAMELENGTH];
                   6424:    double ***varpij;
                   6425: 
                   6426:    strcpy(fileresprob,"PROB_"); 
                   6427:    strcat(fileresprob,fileres);
                   6428:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6429:      printf("Problem with resultfile: %s\n", fileresprob);
                   6430:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6431:    }
                   6432:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6433:    strcat(fileresprobcov,fileresu);
                   6434:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6435:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6436:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6437:    }
                   6438:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6439:    strcat(fileresprobcor,fileresu);
                   6440:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6441:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6442:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6443:    }
                   6444:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6445:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6446:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6447:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6448:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6449:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6450:    pstamp(ficresprob);
                   6451:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6452:    fprintf(ficresprob,"# Age");
                   6453:    pstamp(ficresprobcov);
                   6454:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6455:    fprintf(ficresprobcov,"# Age");
                   6456:    pstamp(ficresprobcor);
                   6457:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6458:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6459: 
                   6460: 
1.222     brouard  6461:    for(i=1; i<=nlstate;i++)
                   6462:      for(j=1; j<=(nlstate+ndeath);j++){
                   6463:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6464:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6465:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6466:      }  
                   6467:    /* fprintf(ficresprob,"\n");
                   6468:       fprintf(ficresprobcov,"\n");
                   6469:       fprintf(ficresprobcor,"\n");
                   6470:    */
                   6471:    xp=vector(1,npar);
                   6472:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6473:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6474:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6475:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6476:    first=1;
                   6477:    fprintf(ficgp,"\n# Routine varprob");
                   6478:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6479:    fprintf(fichtm,"\n");
                   6480: 
1.266     brouard  6481:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6482:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6483:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6484: and drawn. It helps understanding how is the covariance between two incidences.\
                   6485:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6486:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6487: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6488: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6489: standard deviations wide on each axis. <br>\
                   6490:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6491:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6492: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6493: 
1.222     brouard  6494:    cov[1]=1;
                   6495:    /* tj=cptcoveff; */
1.225     brouard  6496:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6497:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6498:    j1=0;
1.224     brouard  6499:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6500:      if  (cptcovn>0) {
                   6501:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6502:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6503:        fprintf(ficresprob, "**********\n#\n");
                   6504:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6505:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6506:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6507:                        
1.222     brouard  6508:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6509:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6510:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6511:                        
                   6512:                        
1.222     brouard  6513:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6514:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6515:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6516:                        
1.222     brouard  6517:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6518:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6519:        fprintf(ficresprobcor, "**********\n#");    
                   6520:        if(invalidvarcomb[j1]){
                   6521:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6522:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6523:         continue;
                   6524:        }
                   6525:      }
                   6526:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6527:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6528:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6529:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6530:      for (age=bage; age<=fage; age ++){ 
                   6531:        cov[2]=age;
                   6532:        if(nagesqr==1)
                   6533:         cov[3]= age*age;
                   6534:        for (k=1; k<=cptcovn;k++) {
                   6535:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6536:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6537:                                                                    * 1  1 1 1 1
                   6538:                                                                    * 2  2 1 1 1
                   6539:                                                                    * 3  1 2 1 1
                   6540:                                                                    */
                   6541:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6542:        }
                   6543:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6544:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6545:        for (k=1; k<=cptcovprod;k++)
                   6546:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6547:                        
                   6548:                        
1.222     brouard  6549:        for(theta=1; theta <=npar; theta++){
                   6550:         for(i=1; i<=npar; i++)
                   6551:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6552:                                
1.222     brouard  6553:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6554:                                
1.222     brouard  6555:         k=0;
                   6556:         for(i=1; i<= (nlstate); i++){
                   6557:           for(j=1; j<=(nlstate+ndeath);j++){
                   6558:             k=k+1;
                   6559:             gp[k]=pmmij[i][j];
                   6560:           }
                   6561:         }
1.220     brouard  6562:                                
1.222     brouard  6563:         for(i=1; i<=npar; i++)
                   6564:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6565:                                
1.222     brouard  6566:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6567:         k=0;
                   6568:         for(i=1; i<=(nlstate); i++){
                   6569:           for(j=1; j<=(nlstate+ndeath);j++){
                   6570:             k=k+1;
                   6571:             gm[k]=pmmij[i][j];
                   6572:           }
                   6573:         }
1.220     brouard  6574:                                
1.222     brouard  6575:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6576:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6577:        }
1.126     brouard  6578: 
1.222     brouard  6579:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6580:         for(theta=1; theta <=npar; theta++)
                   6581:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6582:                        
1.222     brouard  6583:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6584:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6585:                        
1.222     brouard  6586:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6587:                        
1.222     brouard  6588:        k=0;
                   6589:        for(i=1; i<=(nlstate); i++){
                   6590:         for(j=1; j<=(nlstate+ndeath);j++){
                   6591:           k=k+1;
                   6592:           mu[k][(int) age]=pmmij[i][j];
                   6593:         }
                   6594:        }
                   6595:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6596:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6597:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6598:                        
1.222     brouard  6599:        /*printf("\n%d ",(int)age);
                   6600:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6601:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6602:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6603:         }*/
1.220     brouard  6604:                        
1.222     brouard  6605:        fprintf(ficresprob,"\n%d ",(int)age);
                   6606:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6607:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6608:                        
1.222     brouard  6609:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6610:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6611:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6612:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6613:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6614:        }
                   6615:        i=0;
                   6616:        for (k=1; k<=(nlstate);k++){
                   6617:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6618:           i++;
                   6619:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6620:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6621:           for (j=1; j<=i;j++){
                   6622:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6623:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6624:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6625:           }
                   6626:         }
                   6627:        }/* end of loop for state */
                   6628:      } /* end of loop for age */
                   6629:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6630:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6631:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6632:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6633:     
                   6634:      /* Confidence intervalle of pij  */
                   6635:      /*
                   6636:        fprintf(ficgp,"\nunset parametric;unset label");
                   6637:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6638:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6639:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6640:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6641:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6642:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6643:      */
                   6644:                
                   6645:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6646:      first1=1;first2=2;
                   6647:      for (k2=1; k2<=(nlstate);k2++){
                   6648:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6649:         if(l2==k2) continue;
                   6650:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6651:         for (k1=1; k1<=(nlstate);k1++){
                   6652:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6653:             if(l1==k1) continue;
                   6654:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6655:             if(i<=j) continue;
                   6656:             for (age=bage; age<=fage; age ++){ 
                   6657:               if ((int)age %5==0){
                   6658:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6659:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6660:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6661:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6662:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6663:                 c12=cv12/sqrt(v1*v2);
                   6664:                 /* Computing eigen value of matrix of covariance */
                   6665:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6666:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6667:                 if ((lc2 <0) || (lc1 <0) ){
                   6668:                   if(first2==1){
                   6669:                     first1=0;
                   6670:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6671:                   }
                   6672:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6673:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6674:                   /* lc2=fabs(lc2); */
                   6675:                 }
1.220     brouard  6676:                                                                
1.222     brouard  6677:                 /* Eigen vectors */
1.280     brouard  6678:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6679:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6680:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6681:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6682:                 }else
                   6683:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6684:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6685:                 v21=(lc1-v1)/cv12*v11;
                   6686:                 v12=-v21;
                   6687:                 v22=v11;
                   6688:                 tnalp=v21/v11;
                   6689:                 if(first1==1){
                   6690:                   first1=0;
                   6691:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6692:                 }
                   6693:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6694:                 /*printf(fignu*/
                   6695:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6696:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6697:                 if(first==1){
                   6698:                   first=0;
                   6699:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6700:                   fprintf(ficgp,"\nset parametric;unset label");
                   6701:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6702:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6703:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6704:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6705: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6706:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6707:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6708:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6709:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6710:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6711:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6712:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6713:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6714:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6715:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6716:                 }else{
                   6717:                   first=0;
                   6718:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6719:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6720:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6721:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6722:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6723:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6724:                 }/* if first */
                   6725:               } /* age mod 5 */
                   6726:             } /* end loop age */
                   6727:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6728:             first=1;
                   6729:           } /*l12 */
                   6730:         } /* k12 */
                   6731:        } /*l1 */
                   6732:      }/* k1 */
                   6733:    }  /* loop on combination of covariates j1 */
                   6734:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6735:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6736:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6737:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6738:    free_vector(xp,1,npar);
                   6739:    fclose(ficresprob);
                   6740:    fclose(ficresprobcov);
                   6741:    fclose(ficresprobcor);
                   6742:    fflush(ficgp);
                   6743:    fflush(fichtmcov);
                   6744:  }
1.126     brouard  6745: 
                   6746: 
                   6747: /******************* Printing html file ***********/
1.201     brouard  6748: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6749:                  int lastpass, int stepm, int weightopt, char model[],\
                   6750:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6751:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6752:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6753:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6754:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6755: 
                   6756:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6757:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6758: </ul>");
1.237     brouard  6759:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6760: </ul>", model);
1.214     brouard  6761:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6762:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6763:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6764:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6765:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6766:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6767:    fprintf(fichtm,"\
                   6768:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6769:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6770:    fprintf(fichtm,"\
1.217     brouard  6771:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6772:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6773:    fprintf(fichtm,"\
1.126     brouard  6774:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6775:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6776:    fprintf(fichtm,"\
1.217     brouard  6777:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6778:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6779:    fprintf(fichtm,"\
1.211     brouard  6780:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6781:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6782:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6783:    if(prevfcast==1){
                   6784:      fprintf(fichtm,"\
                   6785:  - Prevalence projections by age and states:                           \
1.201     brouard  6786:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6787:    }
1.126     brouard  6788: 
                   6789: 
1.225     brouard  6790:    m=pow(2,cptcoveff);
1.222     brouard  6791:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6792: 
1.264     brouard  6793:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6794: 
                   6795:    jj1=0;
                   6796: 
                   6797:    fprintf(fichtm," \n<ul>");
                   6798:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6799:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6800:      if(m != 1 && TKresult[nres]!= k1)
                   6801:        continue;
                   6802:      jj1++;
                   6803:      if (cptcovn > 0) {
                   6804:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6805:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6806:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6807:        }
                   6808:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6809:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6810:        }
                   6811:        fprintf(fichtm,"\">");
                   6812:        
                   6813:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6814:        fprintf(fichtm,"************ Results for covariates");
                   6815:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6816:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6817:        }
                   6818:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6819:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6820:        }
                   6821:        if(invalidvarcomb[k1]){
                   6822:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6823:         continue;
                   6824:        }
                   6825:        fprintf(fichtm,"</a></li>");
                   6826:      } /* cptcovn >0 */
                   6827:    }
                   6828:      fprintf(fichtm," \n</ul>");
                   6829: 
1.222     brouard  6830:    jj1=0;
1.237     brouard  6831: 
                   6832:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6833:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6834:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6835:        continue;
1.220     brouard  6836: 
1.222     brouard  6837:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6838:      jj1++;
                   6839:      if (cptcovn > 0) {
1.264     brouard  6840:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6841:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6842:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6843:        }
                   6844:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6845:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6846:        }
                   6847:        fprintf(fichtm,"\"</a>");
                   6848:  
1.222     brouard  6849:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6850:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6851:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6852:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6853:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6854:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6855:        }
1.237     brouard  6856:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6857:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6858:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6859:       }
                   6860:        
1.230     brouard  6861:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6862:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6863:        if(invalidvarcomb[k1]){
                   6864:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6865:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6866:         continue;
                   6867:        }
                   6868:      }
                   6869:      /* aij, bij */
1.259     brouard  6870:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6871: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6872:      /* Pij */
1.241     brouard  6873:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6874: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6875:      /* Quasi-incidences */
                   6876:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6877:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6878:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6879: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6880: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6881:      /* Survival functions (period) in state j */
                   6882:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6883:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6884: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6885:      }
                   6886:      /* State specific survival functions (period) */
                   6887:      for(cpt=1; cpt<=nlstate;cpt++){
                   6888:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6889:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283   ! brouard  6890:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6891:      }
                   6892:      /* Period (stable) prevalence in each health state */
                   6893:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6894:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6895: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6896:      }
                   6897:      if(backcast==1){
                   6898:        /* Period (stable) back prevalence in each health state */
                   6899:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6900:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6901: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6902:        }
1.217     brouard  6903:      }
1.222     brouard  6904:      if(prevfcast==1){
                   6905:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6906:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6907:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6908: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6909:        }
                   6910:      }
1.268     brouard  6911:      if(backcast==1){
                   6912:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6913:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6914:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6915:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6916:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6917: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6918:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6919:        }
                   6920:      }
1.220     brouard  6921:         
1.222     brouard  6922:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6923:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6924: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6925:      }
                   6926:      /* } /\* end i1 *\/ */
                   6927:    }/* End k1 */
                   6928:    fprintf(fichtm,"</ul>");
1.126     brouard  6929: 
1.222     brouard  6930:    fprintf(fichtm,"\
1.126     brouard  6931: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6932:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6933:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6934: But because parameters are usually highly correlated (a higher incidence of disability \
                   6935: and a higher incidence of recovery can give very close observed transition) it might \
                   6936: be very useful to look not only at linear confidence intervals estimated from the \
                   6937: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6938: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6939: covariance matrix of the one-step probabilities. \
                   6940: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6941: 
1.222     brouard  6942:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6943:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6944:    fprintf(fichtm,"\
1.126     brouard  6945:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6946:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6947: 
1.222     brouard  6948:    fprintf(fichtm,"\
1.126     brouard  6949:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6950:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6951:    fprintf(fichtm,"\
1.126     brouard  6952:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6953:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6954:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6955:    fprintf(fichtm,"\
1.126     brouard  6956:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6957:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6958:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6959:    fprintf(fichtm,"\
1.128     brouard  6960:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6961:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6962:    fprintf(fichtm,"\
1.128     brouard  6963:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6964:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6965:    fprintf(fichtm,"\
1.126     brouard  6966:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6967:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6968: 
                   6969: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6970: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6971: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6972: /*     <br>",fileres,fileres,fileres,fileres); */
                   6973: /*  else  */
                   6974: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6975:    fflush(fichtm);
                   6976:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6977: 
1.225     brouard  6978:    m=pow(2,cptcoveff);
1.222     brouard  6979:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6980: 
1.222     brouard  6981:    jj1=0;
1.237     brouard  6982: 
1.241     brouard  6983:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6984:    for(k1=1; k1<=m;k1++){
1.253     brouard  6985:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6986:        continue;
1.222     brouard  6987:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6988:      jj1++;
1.126     brouard  6989:      if (cptcovn > 0) {
                   6990:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6991:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6992:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6993:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6994:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6995:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6996:       }
                   6997: 
1.126     brouard  6998:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6999: 
1.222     brouard  7000:        if(invalidvarcomb[k1]){
                   7001:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7002:         continue;
                   7003:        }
1.126     brouard  7004:      }
                   7005:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7006:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7007: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7008: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7009:      }
                   7010:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7011: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7012: true period expectancies (those weighted with period prevalences are also\
                   7013:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7014:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7015: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7016:      /* } /\* end i1 *\/ */
                   7017:    }/* End k1 */
1.241     brouard  7018:   }/* End nres */
1.222     brouard  7019:    fprintf(fichtm,"</ul>");
                   7020:    fflush(fichtm);
1.126     brouard  7021: }
                   7022: 
                   7023: /******************* Gnuplot file **************/
1.270     brouard  7024: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7025: 
                   7026:   char dirfileres[132],optfileres[132];
1.264     brouard  7027:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7028:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7029:   int lv=0, vlv=0, kl=0;
1.130     brouard  7030:   int ng=0;
1.201     brouard  7031:   int vpopbased;
1.223     brouard  7032:   int ioffset; /* variable offset for columns */
1.270     brouard  7033:   int iyearc=1; /* variable column for year of projection  */
                   7034:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7035:   int nres=0; /* Index of resultline */
1.266     brouard  7036:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7037: 
1.126     brouard  7038: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7039: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7040: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7041: /*   } */
                   7042: 
                   7043:   /*#ifdef windows */
                   7044:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7045:   /*#endif */
1.225     brouard  7046:   m=pow(2,cptcoveff);
1.126     brouard  7047: 
1.274     brouard  7048:   /* diagram of the model */
                   7049:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7050:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7051:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7052:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7053: 
                   7054:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7055:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7056:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7057:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7058:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7059:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7060:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7061: 
1.202     brouard  7062:   /* Contribution to likelihood */
                   7063:   /* Plot the probability implied in the likelihood */
1.223     brouard  7064:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7065:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7066:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7067:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7068: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7069:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7070: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7071:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7072:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7073:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7074:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7075:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7076:   for (i=1; i<= nlstate ; i ++) {
                   7077:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7078:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7079:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7080:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7081:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7082:     }
                   7083:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7084:   }
                   7085:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7086:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7087:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7088:   fprintf(ficgp,"\nset out;unset log\n");
                   7089:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7090: 
1.126     brouard  7091:   strcpy(dirfileres,optionfilefiname);
                   7092:   strcpy(optfileres,"vpl");
1.223     brouard  7093:   /* 1eme*/
1.238     brouard  7094:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7095:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7096:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7097:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7098:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7099:          continue;
                   7100:        /* We are interested in selected combination by the resultline */
1.246     brouard  7101:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7102:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7103:        strcpy(gplotlabel,"(");
1.238     brouard  7104:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7105:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7106:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7107:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7108:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7109:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7110:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7111:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7112:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7113:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7114:        }
                   7115:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7116:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7117:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7118:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7119:        }
                   7120:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7121:        /* printf("\n#\n"); */
1.238     brouard  7122:        fprintf(ficgp,"\n#\n");
                   7123:        if(invalidvarcomb[k1]){
1.260     brouard  7124:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7125:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7126:          continue;
                   7127:        }
1.235     brouard  7128:       
1.241     brouard  7129:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7130:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7131:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7132:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7133:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7134:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7135:       /* k1-1 error should be nres-1*/
1.238     brouard  7136:        for (i=1; i<= nlstate ; i ++) {
                   7137:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7138:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7139:        }
1.260     brouard  7140:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7141:        for (i=1; i<= nlstate ; i ++) {
                   7142:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7143:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7144:        } 
1.260     brouard  7145:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7146:        for (i=1; i<= nlstate ; i ++) {
                   7147:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7148:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7149:        }  
1.265     brouard  7150:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7151:        
                   7152:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7153:         if(cptcoveff ==0){
1.271     brouard  7154:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7155:        }else{
                   7156:          kl=0;
                   7157:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7158:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7159:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7160:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7161:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7162:            vlv= nbcode[Tvaraff[k]][lv];
                   7163:            kl++;
                   7164:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7165:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7166:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7167:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7168:            if(k==cptcoveff){
                   7169:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7170:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7171:            }else{
                   7172:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7173:              kl++;
                   7174:            }
                   7175:          } /* end covariate */
                   7176:        } /* end if no covariate */
                   7177: 
1.238     brouard  7178:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7179:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7180:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7181:          if(cptcoveff ==0){
1.245     brouard  7182:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7183:          }else{
                   7184:            kl=0;
                   7185:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7186:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7187:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7188:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7189:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7190:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7191:              kl++;
1.238     brouard  7192:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7193:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7194:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7195:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7196:              if(k==cptcoveff){
1.245     brouard  7197:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7198:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7199:              }else{
                   7200:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7201:                kl++;
                   7202:              }
                   7203:            } /* end covariate */
                   7204:          } /* end if no covariate */
1.268     brouard  7205:          if(backcast == 1){
                   7206:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7207:            /* k1-1 error should be nres-1*/
                   7208:            for (i=1; i<= nlstate ; i ++) {
                   7209:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7210:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7211:            }
1.271     brouard  7212:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7213:            for (i=1; i<= nlstate ; i ++) {
                   7214:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7215:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7216:            } 
1.276     brouard  7217:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7218:            for (i=1; i<= nlstate ; i ++) {
                   7219:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7220:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7221:            } 
1.274     brouard  7222:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7223:          } /* end if backprojcast */
1.238     brouard  7224:        } /* end if backcast */
1.276     brouard  7225:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7226:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7227:       } /* nres */
1.201     brouard  7228:     } /* k1 */
                   7229:   } /* cpt */
1.235     brouard  7230: 
                   7231:   
1.126     brouard  7232:   /*2 eme*/
1.238     brouard  7233:   for (k1=1; k1<= m ; k1 ++){  
                   7234:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7235:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7236:        continue;
                   7237:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7238:       strcpy(gplotlabel,"(");
1.238     brouard  7239:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7240:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7241:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7242:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7243:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7244:        vlv= nbcode[Tvaraff[k]][lv];
                   7245:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7246:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7247:       }
1.237     brouard  7248:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7249:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7250:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7251:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7252:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7253:       }
1.264     brouard  7254:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7255:       fprintf(ficgp,"\n#\n");
1.223     brouard  7256:       if(invalidvarcomb[k1]){
                   7257:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7258:        continue;
                   7259:       }
1.219     brouard  7260:                        
1.241     brouard  7261:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7262:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7263:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7264:        if(vpopbased==0){
1.238     brouard  7265:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7266:        }else
1.238     brouard  7267:          fprintf(ficgp,"\nreplot ");
                   7268:        for (i=1; i<= nlstate+1 ; i ++) {
                   7269:          k=2*i;
1.261     brouard  7270:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7271:          for (j=1; j<= nlstate+1 ; j ++) {
                   7272:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7273:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7274:          }   
                   7275:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7276:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7277:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7278:          for (j=1; j<= nlstate+1 ; j ++) {
                   7279:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7280:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7281:          }   
                   7282:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7283:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7284:          for (j=1; j<= nlstate+1 ; j ++) {
                   7285:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7286:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7287:          }   
                   7288:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7289:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7290:        } /* state */
                   7291:       } /* vpopbased */
1.264     brouard  7292:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7293:     } /* end nres */
                   7294:   } /* k1 end 2 eme*/
                   7295:        
                   7296:        
                   7297:   /*3eme*/
                   7298:   for (k1=1; k1<= m ; k1 ++){
                   7299:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7300:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7301:        continue;
                   7302: 
                   7303:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7304:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7305:        strcpy(gplotlabel,"(");
1.238     brouard  7306:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7307:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7308:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7309:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7310:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7311:          vlv= nbcode[Tvaraff[k]][lv];
                   7312:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7313:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7314:        }
                   7315:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7316:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7317:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7318:        }       
1.264     brouard  7319:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7320:        fprintf(ficgp,"\n#\n");
                   7321:        if(invalidvarcomb[k1]){
                   7322:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7323:          continue;
                   7324:        }
                   7325:                        
                   7326:        /*       k=2+nlstate*(2*cpt-2); */
                   7327:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7328:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7329:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7330:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7331: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7332:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7333:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7334:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7335:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7336:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7337:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7338:                                
1.238     brouard  7339:        */
                   7340:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7341:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7342:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7343:                                
1.238     brouard  7344:        } 
1.261     brouard  7345:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7346:       }
1.264     brouard  7347:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7348:     } /* end nres */
                   7349:   } /* end kl 3eme */
1.126     brouard  7350:   
1.223     brouard  7351:   /* 4eme */
1.201     brouard  7352:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7353:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7354:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7355:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7356:        continue;
1.238     brouard  7357:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7358:        strcpy(gplotlabel,"(");
1.238     brouard  7359:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7360:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7361:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7362:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7363:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7364:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7365:          vlv= nbcode[Tvaraff[k]][lv];
                   7366:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7367:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7368:        }
                   7369:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7370:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7371:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7372:        }       
1.264     brouard  7373:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7374:        fprintf(ficgp,"\n#\n");
                   7375:        if(invalidvarcomb[k1]){
                   7376:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7377:          continue;
1.223     brouard  7378:        }
1.238     brouard  7379:       
1.241     brouard  7380:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7381:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7382:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7383: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7384:        k=3;
                   7385:        for (i=1; i<= nlstate ; i ++){
                   7386:          if(i==1){
                   7387:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7388:          }else{
                   7389:            fprintf(ficgp,", '' ");
                   7390:          }
                   7391:          l=(nlstate+ndeath)*(i-1)+1;
                   7392:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7393:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7394:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7395:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7396:        } /* nlstate */
1.264     brouard  7397:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7398:       } /* end cpt state*/ 
                   7399:     } /* end nres */
                   7400:   } /* end covariate k1 */  
                   7401: 
1.220     brouard  7402: /* 5eme */
1.201     brouard  7403:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7404:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7405:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7406:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7407:        continue;
1.238     brouard  7408:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7409:        strcpy(gplotlabel,"(");
1.238     brouard  7410:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7411:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7412:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7413:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7414:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7415:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7416:          vlv= nbcode[Tvaraff[k]][lv];
                   7417:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7418:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7419:        }
                   7420:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7421:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7422:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7423:        }       
1.264     brouard  7424:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7425:        fprintf(ficgp,"\n#\n");
                   7426:        if(invalidvarcomb[k1]){
                   7427:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7428:          continue;
                   7429:        }
1.227     brouard  7430:       
1.241     brouard  7431:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7432:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7433:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7434: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7435:        k=3;
                   7436:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7437:          if(j==1)
                   7438:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7439:          else
                   7440:            fprintf(ficgp,", '' ");
                   7441:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7442:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7443:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7444:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7445:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7446:        } /* nlstate */
                   7447:        fprintf(ficgp,", '' ");
                   7448:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7449:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7450:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7451:          if(j < nlstate)
                   7452:            fprintf(ficgp,"$%d +",k+l);
                   7453:          else
                   7454:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7455:        }
1.264     brouard  7456:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7457:       } /* end cpt state*/ 
                   7458:     } /* end covariate */  
                   7459:   } /* end nres */
1.227     brouard  7460:   
1.220     brouard  7461: /* 6eme */
1.202     brouard  7462:   /* CV preval stable (period) for each covariate */
1.237     brouard  7463:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7464:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7465:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7466:       continue;
1.255     brouard  7467:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7468:       strcpy(gplotlabel,"(");      
1.211     brouard  7469:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7470:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7471:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7472:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7473:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7474:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7475:        vlv= nbcode[Tvaraff[k]][lv];
                   7476:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7477:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7478:       }
1.237     brouard  7479:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7480:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7481:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7482:       }        
1.264     brouard  7483:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7484:       fprintf(ficgp,"\n#\n");
1.223     brouard  7485:       if(invalidvarcomb[k1]){
1.227     brouard  7486:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7487:        continue;
1.223     brouard  7488:       }
1.227     brouard  7489:       
1.241     brouard  7490:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7491:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7492:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7493: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7494:       k=3; /* Offset */
1.255     brouard  7495:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7496:        if(i==1)
                   7497:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7498:        else
                   7499:          fprintf(ficgp,", '' ");
1.255     brouard  7500:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7501:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7502:        for (j=2; j<= nlstate ; j ++)
                   7503:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7504:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7505:       } /* nlstate */
1.264     brouard  7506:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7507:     } /* end cpt state*/ 
                   7508:   } /* end covariate */  
1.227     brouard  7509:   
                   7510:   
1.220     brouard  7511: /* 7eme */
1.218     brouard  7512:   if(backcast == 1){
1.217     brouard  7513:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7514:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7515:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7516:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7517:        continue;
1.268     brouard  7518:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7519:        strcpy(gplotlabel,"(");      
                   7520:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7521:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7522:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7523:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7524:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7525:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7526:          vlv= nbcode[Tvaraff[k]][lv];
                   7527:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7528:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7529:        }
1.237     brouard  7530:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7531:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7532:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7533:        }       
1.264     brouard  7534:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7535:        fprintf(ficgp,"\n#\n");
                   7536:        if(invalidvarcomb[k1]){
                   7537:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7538:          continue;
                   7539:        }
                   7540:        
1.241     brouard  7541:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7542:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7543:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7544: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7545:        k=3; /* Offset */
1.268     brouard  7546:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7547:          if(i==1)
                   7548:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7549:          else
                   7550:            fprintf(ficgp,", '' ");
                   7551:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7552:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7553:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7554:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7555:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7556:          /* for (j=2; j<= nlstate ; j ++) */
                   7557:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7558:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7559:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7560:        } /* nlstate */
1.264     brouard  7561:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7562:       } /* end cpt state*/ 
                   7563:     } /* end covariate */  
                   7564:   } /* End if backcast */
                   7565:   
1.223     brouard  7566:   /* 8eme */
1.218     brouard  7567:   if(prevfcast==1){
                   7568:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7569:     
1.237     brouard  7570:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7571:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7572:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7573:        continue;
1.211     brouard  7574:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7575:        strcpy(gplotlabel,"(");      
1.227     brouard  7576:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7577:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7578:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7579:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7580:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7581:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7582:          vlv= nbcode[Tvaraff[k]][lv];
                   7583:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7584:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7585:        }
1.237     brouard  7586:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7587:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7588:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7589:        }       
1.264     brouard  7590:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7591:        fprintf(ficgp,"\n#\n");
                   7592:        if(invalidvarcomb[k1]){
                   7593:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7594:          continue;
                   7595:        }
                   7596:        
                   7597:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7598:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7599:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7600:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7601: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7602: 
                   7603:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7604:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7605:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7606:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7607:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7608:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7609:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7610:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7611:          if(i==istart){
1.227     brouard  7612:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7613:          }else{
                   7614:            fprintf(ficgp,",\\\n '' ");
                   7615:          }
                   7616:          if(cptcoveff ==0){ /* No covariate */
                   7617:            ioffset=2; /* Age is in 2 */
                   7618:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7619:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7620:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7621:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7622:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7623:            if(i==nlstate+1){
1.270     brouard  7624:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7625:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7626:              fprintf(ficgp,",\\\n '' ");
                   7627:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7628:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7629:                     offyear,                           \
1.268     brouard  7630:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7631:            }else
1.227     brouard  7632:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7633:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7634:          }else{ /* more than 2 covariates */
1.270     brouard  7635:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7636:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7637:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7638:            iyearc=ioffset-1;
                   7639:            iagec=ioffset;
1.227     brouard  7640:            fprintf(ficgp," u %d:(",ioffset); 
                   7641:            kl=0;
                   7642:            strcpy(gplotcondition,"(");
                   7643:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7644:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7645:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7646:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7647:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7648:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7649:              kl++;
                   7650:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7651:              kl++;
                   7652:              if(k <cptcoveff && cptcoveff>1)
                   7653:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7654:            }
                   7655:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7656:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7657:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7658:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7659:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7660:            if(i==nlstate+1){
1.270     brouard  7661:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7662:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7663:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7664:              fprintf(ficgp," u %d:(",iagec); 
                   7665:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7666:                      iyearc, iagec, offyear,                           \
                   7667:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7668: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7669:            }else{
                   7670:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7671:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7672:            }
                   7673:          } /* end if covariate */
                   7674:        } /* nlstate */
1.264     brouard  7675:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7676:       } /* end cpt state*/
                   7677:     } /* end covariate */
                   7678:   } /* End if prevfcast */
1.227     brouard  7679:   
1.268     brouard  7680:   if(backcast==1){
                   7681:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7682:     
                   7683:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7684:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7685:       if(m != 1 && TKresult[nres]!= k1)
                   7686:        continue;
                   7687:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7688:        strcpy(gplotlabel,"(");      
                   7689:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7690:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7691:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7692:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7693:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7694:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7695:          vlv= nbcode[Tvaraff[k]][lv];
                   7696:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7697:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7698:        }
                   7699:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7700:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7701:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7702:        }       
                   7703:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7704:        fprintf(ficgp,"\n#\n");
                   7705:        if(invalidvarcomb[k1]){
                   7706:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7707:          continue;
                   7708:        }
                   7709:        
                   7710:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7711:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7712:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7713:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7714: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7715: 
                   7716:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7717:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7718:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7719:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7720:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7721:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7722:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7723:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7724:          if(i==istart){
                   7725:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7726:          }else{
                   7727:            fprintf(ficgp,",\\\n '' ");
                   7728:          }
                   7729:          if(cptcoveff ==0){ /* No covariate */
                   7730:            ioffset=2; /* Age is in 2 */
                   7731:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7732:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7733:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7734:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7735:            fprintf(ficgp," u %d:(", ioffset); 
                   7736:            if(i==nlstate+1){
1.270     brouard  7737:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7738:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7739:              fprintf(ficgp,",\\\n '' ");
                   7740:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7741:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7742:                     offbyear,                          \
                   7743:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7744:            }else
                   7745:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7746:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7747:          }else{ /* more than 2 covariates */
1.270     brouard  7748:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7749:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7750:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7751:            iyearc=ioffset-1;
                   7752:            iagec=ioffset;
1.268     brouard  7753:            fprintf(ficgp," u %d:(",ioffset); 
                   7754:            kl=0;
                   7755:            strcpy(gplotcondition,"(");
                   7756:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7757:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7758:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7759:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7760:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7761:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7762:              kl++;
                   7763:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7764:              kl++;
                   7765:              if(k <cptcoveff && cptcoveff>1)
                   7766:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7767:            }
                   7768:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7769:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7770:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7771:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7772:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7773:            if(i==nlstate+1){
1.270     brouard  7774:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7775:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7776:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7777:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7778:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7779:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7780:                      iyearc,iagec,offbyear,                            \
                   7781:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7782: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7783:            }else{
                   7784:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7785:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7786:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7787:            }
                   7788:          } /* end if covariate */
                   7789:        } /* nlstate */
                   7790:        fprintf(ficgp,"\nset out; unset label;\n");
                   7791:       } /* end cpt state*/
                   7792:     } /* end covariate */
                   7793:   } /* End if backcast */
                   7794:   
1.227     brouard  7795:   
1.238     brouard  7796:   /* 9eme writing MLE parameters */
                   7797:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7798:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7799:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7800:     for(k=1; k <=(nlstate+ndeath); k++){
                   7801:       if (k != i) {
1.227     brouard  7802:        fprintf(ficgp,"#   current state %d\n",k);
                   7803:        for(j=1; j <=ncovmodel; j++){
                   7804:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7805:          jk++; 
                   7806:        }
                   7807:        fprintf(ficgp,"\n");
1.126     brouard  7808:       }
                   7809:     }
1.223     brouard  7810:   }
1.187     brouard  7811:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7812:   
1.145     brouard  7813:   /*goto avoid;*/
1.238     brouard  7814:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7815:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7816:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7817:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7818:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7819:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7820:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7821:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7822:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7823:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7824:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7825:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7826:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7827:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7828:   fprintf(ficgp,"#\n");
1.223     brouard  7829:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7830:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7831:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7832:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7833:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7834:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7835:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7836:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7837:        continue;
1.264     brouard  7838:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7839:       strcpy(gplotlabel,"(");
1.276     brouard  7840:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7841:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7842:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7843:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7844:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7845:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7846:        vlv= nbcode[Tvaraff[k]][lv];
                   7847:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7848:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7849:       }
1.237     brouard  7850:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7851:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7852:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7853:       }        
1.264     brouard  7854:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7855:       fprintf(ficgp,"\n#\n");
1.264     brouard  7856:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7857:       fprintf(ficgp,"\nset key outside ");
                   7858:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7859:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7860:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7861:       if (ng==1){
                   7862:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7863:        fprintf(ficgp,"\nunset log y");
                   7864:       }else if (ng==2){
                   7865:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7866:        fprintf(ficgp,"\nset log y");
                   7867:       }else if (ng==3){
                   7868:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7869:        fprintf(ficgp,"\nset log y");
                   7870:       }else
                   7871:        fprintf(ficgp,"\nunset title ");
                   7872:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7873:       i=1;
                   7874:       for(k2=1; k2<=nlstate; k2++) {
                   7875:        k3=i;
                   7876:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7877:          if (k != k2){
                   7878:            switch( ng) {
                   7879:            case 1:
                   7880:              if(nagesqr==0)
                   7881:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7882:              else /* nagesqr =1 */
                   7883:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7884:              break;
                   7885:            case 2: /* ng=2 */
                   7886:              if(nagesqr==0)
                   7887:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7888:              else /* nagesqr =1 */
                   7889:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7890:              break;
                   7891:            case 3:
                   7892:              if(nagesqr==0)
                   7893:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7894:              else /* nagesqr =1 */
                   7895:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7896:              break;
                   7897:            }
                   7898:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7899:            ijp=1; /* product no age */
                   7900:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7901:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7902:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7903:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7904:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7905:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7906:                    if(DummyV[j]==0){
                   7907:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7908:                    }else{ /* quantitative */
                   7909:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7910:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7911:                    }
                   7912:                    ij++;
1.237     brouard  7913:                  }
1.268     brouard  7914:                } 
                   7915:              }else if(cptcovprod >0){
                   7916:                if(j==Tprod[ijp]) { /* */ 
                   7917:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7918:                  if(ijp <=cptcovprod) { /* Product */
                   7919:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7920:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7921:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7922:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7923:                      }else{ /* Vn is dummy and Vm is quanti */
                   7924:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7925:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7926:                      }
                   7927:                    }else{ /* Vn*Vm Vn is quanti */
                   7928:                      if(DummyV[Tvard[ijp][2]]==0){
                   7929:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7930:                      }else{ /* Both quanti */
                   7931:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7932:                      }
1.237     brouard  7933:                    }
1.268     brouard  7934:                    ijp++;
1.237     brouard  7935:                  }
1.268     brouard  7936:                } /* end Tprod */
1.237     brouard  7937:              } else{  /* simple covariate */
1.264     brouard  7938:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7939:                if(Dummy[j]==0){
                   7940:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7941:                }else{ /* quantitative */
                   7942:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7943:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7944:                }
1.237     brouard  7945:              } /* end simple */
                   7946:            } /* end j */
1.223     brouard  7947:          }else{
                   7948:            i=i-ncovmodel;
                   7949:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7950:              fprintf(ficgp," (1.");
                   7951:          }
1.227     brouard  7952:          
1.223     brouard  7953:          if(ng != 1){
                   7954:            fprintf(ficgp,")/(1");
1.227     brouard  7955:            
1.264     brouard  7956:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7957:              if(nagesqr==0)
1.264     brouard  7958:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7959:              else /* nagesqr =1 */
1.264     brouard  7960:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7961:               
1.223     brouard  7962:              ij=1;
                   7963:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7964:                 if(cptcovage >0){ 
                   7965:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7966:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7967:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7968:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7969:                       ij++;
                   7970:                     }
                   7971:                   }
                   7972:                 }else
                   7973:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7974:              }
                   7975:              fprintf(ficgp,")");
                   7976:            }
                   7977:            fprintf(ficgp,")");
                   7978:            if(ng ==2)
1.276     brouard  7979:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7980:            else /* ng= 3 */
1.276     brouard  7981:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7982:          }else{ /* end ng <> 1 */
                   7983:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  7984:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7985:          }
                   7986:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7987:            fprintf(ficgp,",");
                   7988:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7989:            fprintf(ficgp,",");
                   7990:          i=i+ncovmodel;
                   7991:        } /* end k */
                   7992:       } /* end k2 */
1.276     brouard  7993:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   7994:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  7995:     } /* end k1 */
1.223     brouard  7996:   } /* end ng */
                   7997:   /* avoid: */
                   7998:   fflush(ficgp); 
1.126     brouard  7999: }  /* end gnuplot */
                   8000: 
                   8001: 
                   8002: /*************** Moving average **************/
1.219     brouard  8003: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8004:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8005:    
1.222     brouard  8006:    int i, cpt, cptcod;
                   8007:    int modcovmax =1;
                   8008:    int mobilavrange, mob;
                   8009:    int iage=0;
                   8010: 
1.266     brouard  8011:    double sum=0., sumr=0.;
1.222     brouard  8012:    double age;
1.266     brouard  8013:    double *sumnewp, *sumnewm, *sumnewmr;
                   8014:    double *agemingood, *agemaxgood; 
                   8015:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8016:   
                   8017:   
1.278     brouard  8018:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8019:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8020: 
                   8021:    sumnewp = vector(1,ncovcombmax);
                   8022:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8023:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8024:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8025:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8026:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8027:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8028: 
                   8029:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8030:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8031:      sumnewp[cptcod]=0.;
1.266     brouard  8032:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8033:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8034:    }
                   8035:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8036:   
1.266     brouard  8037:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8038:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8039:      else mobilavrange=mobilav;
                   8040:      for (age=bage; age<=fage; age++)
                   8041:        for (i=1; i<=nlstate;i++)
                   8042:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8043:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8044:      /* We keep the original values on the extreme ages bage, fage and for 
                   8045:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8046:        we use a 5 terms etc. until the borders are no more concerned. 
                   8047:      */ 
                   8048:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8049:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8050:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8051:           sumnewm[cptcod]=0.;
                   8052:           for (i=1; i<=nlstate;i++){
1.222     brouard  8053:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8054:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8055:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8056:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8057:             }
                   8058:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8059:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8060:           } /* end i */
                   8061:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8062:         } /* end cptcod */
1.222     brouard  8063:        }/* end age */
                   8064:      }/* end mob */
1.266     brouard  8065:    }else{
                   8066:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8067:      return -1;
1.266     brouard  8068:    }
                   8069: 
                   8070:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8071:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8072:      if(invalidvarcomb[cptcod]){
                   8073:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8074:        continue;
                   8075:      }
1.219     brouard  8076: 
1.266     brouard  8077:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8078:        sumnewm[cptcod]=0.;
                   8079:        sumnewmr[cptcod]=0.;
                   8080:        for (i=1; i<=nlstate;i++){
                   8081:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8082:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8083:        }
                   8084:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8085:         agemingoodr[cptcod]=age;
                   8086:        }
                   8087:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8088:           agemingood[cptcod]=age;
                   8089:        }
                   8090:      } /* age */
                   8091:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8092:        sumnewm[cptcod]=0.;
1.266     brouard  8093:        sumnewmr[cptcod]=0.;
1.222     brouard  8094:        for (i=1; i<=nlstate;i++){
                   8095:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8096:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8097:        }
                   8098:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8099:         agemaxgoodr[cptcod]=age;
1.222     brouard  8100:        }
                   8101:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8102:         agemaxgood[cptcod]=age;
                   8103:        }
                   8104:      } /* age */
                   8105:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8106:      /* but they will change */
                   8107:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8108:        sumnewm[cptcod]=0.;
                   8109:        sumnewmr[cptcod]=0.;
                   8110:        for (i=1; i<=nlstate;i++){
                   8111:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8112:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8113:        }
                   8114:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8115:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8116:           agemaxgoodr[cptcod]=age;  /* age min */
                   8117:           for (i=1; i<=nlstate;i++)
                   8118:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8119:         }else{ /* bad we change the value with the values of good ages */
                   8120:           for (i=1; i<=nlstate;i++){
                   8121:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8122:           } /* i */
                   8123:         } /* end bad */
                   8124:        }else{
                   8125:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8126:           agemaxgood[cptcod]=age;
                   8127:         }else{ /* bad we change the value with the values of good ages */
                   8128:           for (i=1; i<=nlstate;i++){
                   8129:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8130:           } /* i */
                   8131:         } /* end bad */
                   8132:        }/* end else */
                   8133:        sum=0.;sumr=0.;
                   8134:        for (i=1; i<=nlstate;i++){
                   8135:         sum+=mobaverage[(int)age][i][cptcod];
                   8136:         sumr+=probs[(int)age][i][cptcod];
                   8137:        }
                   8138:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8139:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8140:        } /* end bad */
                   8141:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8142:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8143:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8144:        } /* end bad */
                   8145:      }/* age */
1.266     brouard  8146: 
                   8147:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8148:        sumnewm[cptcod]=0.;
1.266     brouard  8149:        sumnewmr[cptcod]=0.;
1.222     brouard  8150:        for (i=1; i<=nlstate;i++){
                   8151:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8152:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8153:        } 
                   8154:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8155:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8156:           agemingoodr[cptcod]=age;
                   8157:           for (i=1; i<=nlstate;i++)
                   8158:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8159:         }else{ /* bad we change the value with the values of good ages */
                   8160:           for (i=1; i<=nlstate;i++){
                   8161:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8162:           } /* i */
                   8163:         } /* end bad */
                   8164:        }else{
                   8165:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8166:           agemingood[cptcod]=age;
                   8167:         }else{ /* bad */
                   8168:           for (i=1; i<=nlstate;i++){
                   8169:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8170:           } /* i */
                   8171:         } /* end bad */
                   8172:        }/* end else */
                   8173:        sum=0.;sumr=0.;
                   8174:        for (i=1; i<=nlstate;i++){
                   8175:         sum+=mobaverage[(int)age][i][cptcod];
                   8176:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8177:        }
1.266     brouard  8178:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8179:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8180:        } /* end bad */
                   8181:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8182:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8183:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8184:        } /* end bad */
                   8185:      }/* age */
1.266     brouard  8186: 
1.222     brouard  8187:                
                   8188:      for (age=bage; age<=fage; age++){
1.235     brouard  8189:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8190:        sumnewp[cptcod]=0.;
                   8191:        sumnewm[cptcod]=0.;
                   8192:        for (i=1; i<=nlstate;i++){
                   8193:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8194:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8195:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8196:        }
                   8197:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8198:      }
                   8199:      /* printf("\n"); */
                   8200:      /* } */
1.266     brouard  8201: 
1.222     brouard  8202:      /* brutal averaging */
1.266     brouard  8203:      /* for (i=1; i<=nlstate;i++){ */
                   8204:      /*   for (age=1; age<=bage; age++){ */
                   8205:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8206:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8207:      /*   }     */
                   8208:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8209:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8210:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8211:      /*   } */
                   8212:      /* } /\* end i status *\/ */
                   8213:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8214:      /*   for (age=1; age<=AGESUP; age++){ */
                   8215:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8216:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8217:      /*   } */
                   8218:      /* } */
1.222     brouard  8219:    }/* end cptcod */
1.266     brouard  8220:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8221:    free_vector(agemaxgood,1, ncovcombmax);
                   8222:    free_vector(agemingood,1, ncovcombmax);
                   8223:    free_vector(agemingoodr,1, ncovcombmax);
                   8224:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8225:    free_vector(sumnewm,1, ncovcombmax);
                   8226:    free_vector(sumnewp,1, ncovcombmax);
                   8227:    return 0;
                   8228:  }/* End movingaverage */
1.218     brouard  8229:  
1.126     brouard  8230: 
                   8231: /************** Forecasting ******************/
1.269     brouard  8232:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8233:   /* proj1, year, month, day of starting projection 
                   8234:      agemin, agemax range of age
                   8235:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8236:      anproj2 year of en of projection (same day and month as proj1).
                   8237:   */
1.267     brouard  8238:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8239:   double agec; /* generic age */
                   8240:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8241:   double *popeffectif,*popcount;
                   8242:   double ***p3mat;
1.218     brouard  8243:   /* double ***mobaverage; */
1.126     brouard  8244:   char fileresf[FILENAMELENGTH];
                   8245: 
                   8246:   agelim=AGESUP;
1.211     brouard  8247:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8248:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8249:      We still use firstpass and lastpass as another selection.
                   8250:   */
1.214     brouard  8251:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8252:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8253:  
1.201     brouard  8254:   strcpy(fileresf,"F_"); 
                   8255:   strcat(fileresf,fileresu);
1.126     brouard  8256:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8257:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8258:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8259:   }
1.235     brouard  8260:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8261:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8262: 
1.225     brouard  8263:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8264: 
                   8265: 
                   8266:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8267:   if (stepm<=12) stepsize=1;
                   8268:   if(estepm < stepm){
                   8269:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8270:   }
1.270     brouard  8271:   else{
                   8272:     hstepm=estepm;   
                   8273:   }
                   8274:   if(estepm > stepm){ /* Yes every two year */
                   8275:     stepsize=2;
                   8276:   }
1.126     brouard  8277: 
                   8278:   hstepm=hstepm/stepm; 
                   8279:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8280:                                fractional in yp1 */
                   8281:   anprojmean=yp;
                   8282:   yp2=modf((yp1*12),&yp);
                   8283:   mprojmean=yp;
                   8284:   yp1=modf((yp2*30.5),&yp);
                   8285:   jprojmean=yp;
                   8286:   if(jprojmean==0) jprojmean=1;
                   8287:   if(mprojmean==0) jprojmean=1;
                   8288: 
1.227     brouard  8289:   i1=pow(2,cptcoveff);
1.126     brouard  8290:   if (cptcovn < 1){i1=1;}
                   8291:   
                   8292:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8293:   
                   8294:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8295:   
1.126     brouard  8296: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8297:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8298:   for(k=1; k<=i1;k++){
1.253     brouard  8299:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8300:       continue;
1.227     brouard  8301:     if(invalidvarcomb[k]){
                   8302:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8303:       continue;
                   8304:     }
                   8305:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8306:     for(j=1;j<=cptcoveff;j++) {
                   8307:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8308:     }
1.235     brouard  8309:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8310:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8311:     }
1.227     brouard  8312:     fprintf(ficresf," yearproj age");
                   8313:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8314:       for(i=1; i<=nlstate;i++)               
                   8315:        fprintf(ficresf," p%d%d",i,j);
                   8316:       fprintf(ficresf," wp.%d",j);
                   8317:     }
                   8318:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8319:       fprintf(ficresf,"\n");
                   8320:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8321:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8322:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8323:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8324:        nhstepm = nhstepm/hstepm; 
                   8325:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8326:        oldm=oldms;savm=savms;
1.268     brouard  8327:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8328:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8329:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8330:        for (h=0; h<=nhstepm; h++){
                   8331:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8332:            break;
                   8333:          }
                   8334:        }
                   8335:        fprintf(ficresf,"\n");
                   8336:        for(j=1;j<=cptcoveff;j++) 
                   8337:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8338:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8339:        
                   8340:        for(j=1; j<=nlstate+ndeath;j++) {
                   8341:          ppij=0.;
                   8342:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8343:            if (mobilav>=1)
                   8344:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8345:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8346:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8347:            }
1.268     brouard  8348:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8349:          } /* end i */
                   8350:          fprintf(ficresf," %.3f", ppij);
                   8351:        }/* end j */
1.227     brouard  8352:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8353:       } /* end agec */
1.266     brouard  8354:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8355:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8356:     } /* end yearp */
                   8357:   } /* end  k */
1.219     brouard  8358:        
1.126     brouard  8359:   fclose(ficresf);
1.215     brouard  8360:   printf("End of Computing forecasting \n");
                   8361:   fprintf(ficlog,"End of Computing forecasting\n");
                   8362: 
1.126     brouard  8363: }
                   8364: 
1.269     brouard  8365: /************** Back Forecasting ******************/
                   8366:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8367:   /* back1, year, month, day of starting backection
                   8368:      agemin, agemax range of age
                   8369:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8370:      anback2 year of end of backprojection (same day and month as back1).
                   8371:      prevacurrent and prev are prevalences.
1.267     brouard  8372:   */
                   8373:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8374:   double agec; /* generic age */
1.268     brouard  8375:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8376:   double *popeffectif,*popcount;
                   8377:   double ***p3mat;
                   8378:   /* double ***mobaverage; */
                   8379:   char fileresfb[FILENAMELENGTH];
                   8380:  
1.268     brouard  8381:   agelim=AGEINF;
1.267     brouard  8382:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8383:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8384:      We still use firstpass and lastpass as another selection.
                   8385:   */
                   8386:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8387:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8388: 
                   8389:   /*Do we need to compute prevalence again?*/
                   8390: 
                   8391:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8392:   
                   8393:   strcpy(fileresfb,"FB_");
                   8394:   strcat(fileresfb,fileresu);
                   8395:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8396:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8397:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8398:   }
                   8399:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8400:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8401:   
                   8402:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8403:   
                   8404:    
                   8405:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8406:   if (stepm<=12) stepsize=1;
                   8407:   if(estepm < stepm){
                   8408:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8409:   }
1.270     brouard  8410:   else{
                   8411:     hstepm=estepm;   
                   8412:   }
                   8413:   if(estepm >= stepm){ /* Yes every two year */
                   8414:     stepsize=2;
                   8415:   }
1.267     brouard  8416:   
                   8417:   hstepm=hstepm/stepm;
                   8418:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8419:                                fractional in yp1 */
                   8420:   anprojmean=yp;
                   8421:   yp2=modf((yp1*12),&yp);
                   8422:   mprojmean=yp;
                   8423:   yp1=modf((yp2*30.5),&yp);
                   8424:   jprojmean=yp;
                   8425:   if(jprojmean==0) jprojmean=1;
                   8426:   if(mprojmean==0) jprojmean=1;
                   8427:   
                   8428:   i1=pow(2,cptcoveff);
                   8429:   if (cptcovn < 1){i1=1;}
                   8430:   
                   8431:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8432:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8433:   
                   8434:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8435:   
                   8436:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8437:   for(k=1; k<=i1;k++){
                   8438:     if(i1 != 1 && TKresult[nres]!= k)
                   8439:       continue;
                   8440:     if(invalidvarcomb[k]){
                   8441:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8442:       continue;
                   8443:     }
1.268     brouard  8444:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8445:     for(j=1;j<=cptcoveff;j++) {
                   8446:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8447:     }
                   8448:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8449:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8450:     }
                   8451:     fprintf(ficresfb," yearbproj age");
                   8452:     for(j=1; j<=nlstate+ndeath;j++){
                   8453:       for(i=1; i<=nlstate;i++)
1.268     brouard  8454:        fprintf(ficresfb," b%d%d",i,j);
                   8455:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8456:     }
                   8457:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8458:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8459:       fprintf(ficresfb,"\n");
                   8460:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8461:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8462:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8463:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8464:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8465:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8466:        nhstepm = nhstepm/hstepm;
                   8467:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8468:        oldm=oldms;savm=savms;
1.268     brouard  8469:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8470:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8471:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8472:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8473:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8474:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8475:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8476:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8477:            break;
                   8478:          }
                   8479:        }
                   8480:        fprintf(ficresfb,"\n");
                   8481:        for(j=1;j<=cptcoveff;j++)
                   8482:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8483:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8484:        for(i=1; i<=nlstate+ndeath;i++) {
                   8485:          ppij=0.;ppi=0.;
                   8486:          for(j=1; j<=nlstate;j++) {
                   8487:            /* if (mobilav==1) */
1.269     brouard  8488:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8489:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8490:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8491:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8492:              /* else { */
                   8493:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8494:              /* } */
1.268     brouard  8495:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8496:          } /* end j */
                   8497:          if(ppi <0.99){
                   8498:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8499:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8500:          }
                   8501:          fprintf(ficresfb," %.3f", ppij);
                   8502:        }/* end j */
1.267     brouard  8503:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8504:       } /* end agec */
                   8505:     } /* end yearp */
                   8506:   } /* end k */
1.217     brouard  8507:   
1.267     brouard  8508:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8509:   
1.267     brouard  8510:   fclose(ficresfb);
                   8511:   printf("End of Computing Back forecasting \n");
                   8512:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8513:        
1.267     brouard  8514: }
1.217     brouard  8515: 
1.269     brouard  8516: /* Variance of prevalence limit: varprlim */
                   8517:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8518:     /*------- Variance of period (stable) prevalence------*/   
                   8519:  
                   8520:    char fileresvpl[FILENAMELENGTH];  
                   8521:    FILE *ficresvpl;
                   8522:    double **oldm, **savm;
                   8523:    double **varpl; /* Variances of prevalence limits by age */   
                   8524:    int i1, k, nres, j ;
                   8525:    
                   8526:     strcpy(fileresvpl,"VPL_");
                   8527:     strcat(fileresvpl,fileresu);
                   8528:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8529:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8530:       exit(0);
                   8531:     }
                   8532:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8533:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8534:     
                   8535:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8536:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8537:     
                   8538:     i1=pow(2,cptcoveff);
                   8539:     if (cptcovn < 1){i1=1;}
                   8540: 
                   8541:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8542:     for(k=1; k<=i1;k++){
                   8543:       if(i1 != 1 && TKresult[nres]!= k)
                   8544:        continue;
                   8545:       fprintf(ficresvpl,"\n#****** ");
                   8546:       printf("\n#****** ");
                   8547:       fprintf(ficlog,"\n#****** ");
                   8548:       for(j=1;j<=cptcoveff;j++) {
                   8549:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8550:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8551:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8552:       }
                   8553:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8554:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8555:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8556:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8557:       }        
                   8558:       fprintf(ficresvpl,"******\n");
                   8559:       printf("******\n");
                   8560:       fprintf(ficlog,"******\n");
                   8561:       
                   8562:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8563:       oldm=oldms;savm=savms;
                   8564:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8565:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8566:       /*}*/
                   8567:     }
                   8568:     
                   8569:     fclose(ficresvpl);
                   8570:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8571:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8572: 
                   8573:  }
                   8574: /* Variance of back prevalence: varbprlim */
                   8575:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8576:       /*------- Variance of back (stable) prevalence------*/
                   8577: 
                   8578:    char fileresvbl[FILENAMELENGTH];  
                   8579:    FILE  *ficresvbl;
                   8580: 
                   8581:    double **oldm, **savm;
                   8582:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8583:    int i1, k, nres, j ;
                   8584: 
                   8585:    strcpy(fileresvbl,"VBL_");
                   8586:    strcat(fileresvbl,fileresu);
                   8587:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8588:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8589:      exit(0);
                   8590:    }
                   8591:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8592:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8593:    
                   8594:    
                   8595:    i1=pow(2,cptcoveff);
                   8596:    if (cptcovn < 1){i1=1;}
                   8597:    
                   8598:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8599:      for(k=1; k<=i1;k++){
                   8600:        if(i1 != 1 && TKresult[nres]!= k)
                   8601:         continue;
                   8602:        fprintf(ficresvbl,"\n#****** ");
                   8603:        printf("\n#****** ");
                   8604:        fprintf(ficlog,"\n#****** ");
                   8605:        for(j=1;j<=cptcoveff;j++) {
                   8606:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8607:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8608:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8609:        }
                   8610:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8611:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8612:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8613:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8614:        }
                   8615:        fprintf(ficresvbl,"******\n");
                   8616:        printf("******\n");
                   8617:        fprintf(ficlog,"******\n");
                   8618:        
                   8619:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8620:        oldm=oldms;savm=savms;
                   8621:        
                   8622:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8623:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8624:        /*}*/
                   8625:      }
                   8626:    
                   8627:    fclose(ficresvbl);
                   8628:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8629:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8630: 
                   8631:  } /* End of varbprlim */
                   8632: 
1.126     brouard  8633: /************** Forecasting *****not tested NB*************/
1.227     brouard  8634: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8635:   
1.227     brouard  8636: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8637: /*   int *popage; */
                   8638: /*   double calagedatem, agelim, kk1, kk2; */
                   8639: /*   double *popeffectif,*popcount; */
                   8640: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8641: /*   /\* double ***mobaverage; *\/ */
                   8642: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8643: 
1.227     brouard  8644: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8645: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8646: /*   agelim=AGESUP; */
                   8647: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8648:   
1.227     brouard  8649: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8650:   
                   8651:   
1.227     brouard  8652: /*   strcpy(filerespop,"POP_");  */
                   8653: /*   strcat(filerespop,fileresu); */
                   8654: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8655: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8656: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8657: /*   } */
                   8658: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8659: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8660: 
1.227     brouard  8661: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8662: 
1.227     brouard  8663: /*   /\* if (mobilav!=0) { *\/ */
                   8664: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8665: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8666: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8667: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8668: /*   /\*   } *\/ */
                   8669: /*   /\* } *\/ */
1.126     brouard  8670: 
1.227     brouard  8671: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8672: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8673:   
1.227     brouard  8674: /*   agelim=AGESUP; */
1.126     brouard  8675:   
1.227     brouard  8676: /*   hstepm=1; */
                   8677: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8678:        
1.227     brouard  8679: /*   if (popforecast==1) { */
                   8680: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8681: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8682: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8683: /*     }  */
                   8684: /*     popage=ivector(0,AGESUP); */
                   8685: /*     popeffectif=vector(0,AGESUP); */
                   8686: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8687:     
1.227     brouard  8688: /*     i=1;    */
                   8689: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8690:     
1.227     brouard  8691: /*     imx=i; */
                   8692: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8693: /*   } */
1.218     brouard  8694:   
1.227     brouard  8695: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8696: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8697: /*       k=k+1; */
                   8698: /*       fprintf(ficrespop,"\n#******"); */
                   8699: /*       for(j=1;j<=cptcoveff;j++) { */
                   8700: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8701: /*       } */
                   8702: /*       fprintf(ficrespop,"******\n"); */
                   8703: /*       fprintf(ficrespop,"# Age"); */
                   8704: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8705: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8706:       
1.227     brouard  8707: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8708: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8709:        
1.227     brouard  8710: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8711: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8712: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8713:          
1.227     brouard  8714: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8715: /*       oldm=oldms;savm=savms; */
                   8716: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8717:          
1.227     brouard  8718: /*       for (h=0; h<=nhstepm; h++){ */
                   8719: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8720: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8721: /*         }  */
                   8722: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8723: /*           kk1=0.;kk2=0; */
                   8724: /*           for(i=1; i<=nlstate;i++) {               */
                   8725: /*             if (mobilav==1)  */
                   8726: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8727: /*             else { */
                   8728: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8729: /*             } */
                   8730: /*           } */
                   8731: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8732: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8733: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8734: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8735: /*           } */
                   8736: /*         } */
                   8737: /*         for(i=1; i<=nlstate;i++){ */
                   8738: /*           kk1=0.; */
                   8739: /*           for(j=1; j<=nlstate;j++){ */
                   8740: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8741: /*           } */
                   8742: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8743: /*         } */
1.218     brouard  8744:            
1.227     brouard  8745: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8746: /*           for(j=1; j<=nlstate;j++)  */
                   8747: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8748: /*       } */
                   8749: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8750: /*     } */
                   8751: /*       } */
1.218     brouard  8752:       
1.227     brouard  8753: /*       /\******\/ */
1.218     brouard  8754:       
1.227     brouard  8755: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8756: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8757: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8758: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8759: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8760:          
1.227     brouard  8761: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8762: /*       oldm=oldms;savm=savms; */
                   8763: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8764: /*       for (h=0; h<=nhstepm; h++){ */
                   8765: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8766: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8767: /*         }  */
                   8768: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8769: /*           kk1=0.;kk2=0; */
                   8770: /*           for(i=1; i<=nlstate;i++) {               */
                   8771: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8772: /*           } */
                   8773: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8774: /*         } */
                   8775: /*       } */
                   8776: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8777: /*     } */
                   8778: /*       } */
                   8779: /*     }  */
                   8780: /*   } */
1.218     brouard  8781:   
1.227     brouard  8782: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8783:   
1.227     brouard  8784: /*   if (popforecast==1) { */
                   8785: /*     free_ivector(popage,0,AGESUP); */
                   8786: /*     free_vector(popeffectif,0,AGESUP); */
                   8787: /*     free_vector(popcount,0,AGESUP); */
                   8788: /*   } */
                   8789: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8790: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8791: /*   fclose(ficrespop); */
                   8792: /* } /\* End of popforecast *\/ */
1.218     brouard  8793:  
1.126     brouard  8794: int fileappend(FILE *fichier, char *optionfich)
                   8795: {
                   8796:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8797:     printf("Problem with file: %s\n", optionfich);
                   8798:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8799:     return (0);
                   8800:   }
                   8801:   fflush(fichier);
                   8802:   return (1);
                   8803: }
                   8804: 
                   8805: 
                   8806: /**************** function prwizard **********************/
                   8807: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8808: {
                   8809: 
                   8810:   /* Wizard to print covariance matrix template */
                   8811: 
1.164     brouard  8812:   char ca[32], cb[32];
                   8813:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8814:   int numlinepar;
                   8815: 
                   8816:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8817:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8818:   for(i=1; i <=nlstate; i++){
                   8819:     jj=0;
                   8820:     for(j=1; j <=nlstate+ndeath; j++){
                   8821:       if(j==i) continue;
                   8822:       jj++;
                   8823:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8824:       printf("%1d%1d",i,j);
                   8825:       fprintf(ficparo,"%1d%1d",i,j);
                   8826:       for(k=1; k<=ncovmodel;k++){
                   8827:        /*        printf(" %lf",param[i][j][k]); */
                   8828:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8829:        printf(" 0.");
                   8830:        fprintf(ficparo," 0.");
                   8831:       }
                   8832:       printf("\n");
                   8833:       fprintf(ficparo,"\n");
                   8834:     }
                   8835:   }
                   8836:   printf("# Scales (for hessian or gradient estimation)\n");
                   8837:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8838:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8839:   for(i=1; i <=nlstate; i++){
                   8840:     jj=0;
                   8841:     for(j=1; j <=nlstate+ndeath; j++){
                   8842:       if(j==i) continue;
                   8843:       jj++;
                   8844:       fprintf(ficparo,"%1d%1d",i,j);
                   8845:       printf("%1d%1d",i,j);
                   8846:       fflush(stdout);
                   8847:       for(k=1; k<=ncovmodel;k++){
                   8848:        /*      printf(" %le",delti3[i][j][k]); */
                   8849:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8850:        printf(" 0.");
                   8851:        fprintf(ficparo," 0.");
                   8852:       }
                   8853:       numlinepar++;
                   8854:       printf("\n");
                   8855:       fprintf(ficparo,"\n");
                   8856:     }
                   8857:   }
                   8858:   printf("# Covariance matrix\n");
                   8859: /* # 121 Var(a12)\n\ */
                   8860: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8861: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8862: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8863: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8864: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8865: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8866: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8867:   fflush(stdout);
                   8868:   fprintf(ficparo,"# Covariance matrix\n");
                   8869:   /* # 121 Var(a12)\n\ */
                   8870:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8871:   /* #   ...\n\ */
                   8872:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8873:   
                   8874:   for(itimes=1;itimes<=2;itimes++){
                   8875:     jj=0;
                   8876:     for(i=1; i <=nlstate; i++){
                   8877:       for(j=1; j <=nlstate+ndeath; j++){
                   8878:        if(j==i) continue;
                   8879:        for(k=1; k<=ncovmodel;k++){
                   8880:          jj++;
                   8881:          ca[0]= k+'a'-1;ca[1]='\0';
                   8882:          if(itimes==1){
                   8883:            printf("#%1d%1d%d",i,j,k);
                   8884:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8885:          }else{
                   8886:            printf("%1d%1d%d",i,j,k);
                   8887:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8888:            /*  printf(" %.5le",matcov[i][j]); */
                   8889:          }
                   8890:          ll=0;
                   8891:          for(li=1;li <=nlstate; li++){
                   8892:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8893:              if(lj==li) continue;
                   8894:              for(lk=1;lk<=ncovmodel;lk++){
                   8895:                ll++;
                   8896:                if(ll<=jj){
                   8897:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8898:                  if(ll<jj){
                   8899:                    if(itimes==1){
                   8900:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8901:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8902:                    }else{
                   8903:                      printf(" 0.");
                   8904:                      fprintf(ficparo," 0.");
                   8905:                    }
                   8906:                  }else{
                   8907:                    if(itimes==1){
                   8908:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8909:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8910:                    }else{
                   8911:                      printf(" 0.");
                   8912:                      fprintf(ficparo," 0.");
                   8913:                    }
                   8914:                  }
                   8915:                }
                   8916:              } /* end lk */
                   8917:            } /* end lj */
                   8918:          } /* end li */
                   8919:          printf("\n");
                   8920:          fprintf(ficparo,"\n");
                   8921:          numlinepar++;
                   8922:        } /* end k*/
                   8923:       } /*end j */
                   8924:     } /* end i */
                   8925:   } /* end itimes */
                   8926: 
                   8927: } /* end of prwizard */
                   8928: /******************* Gompertz Likelihood ******************************/
                   8929: double gompertz(double x[])
                   8930: { 
                   8931:   double A,B,L=0.0,sump=0.,num=0.;
                   8932:   int i,n=0; /* n is the size of the sample */
                   8933: 
1.220     brouard  8934:   for (i=1;i<=imx ; i++) {
1.126     brouard  8935:     sump=sump+weight[i];
                   8936:     /*    sump=sump+1;*/
                   8937:     num=num+1;
                   8938:   }
                   8939:  
                   8940:  
                   8941:   /* for (i=0; i<=imx; i++) 
                   8942:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8943: 
                   8944:   for (i=1;i<=imx ; i++)
                   8945:     {
                   8946:       if (cens[i] == 1 && wav[i]>1)
                   8947:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8948:       
                   8949:       if (cens[i] == 0 && wav[i]>1)
                   8950:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8951:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8952:       
                   8953:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8954:       if (wav[i] > 1 ) { /* ??? */
                   8955:        L=L+A*weight[i];
                   8956:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8957:       }
                   8958:     }
                   8959: 
                   8960:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8961:  
                   8962:   return -2*L*num/sump;
                   8963: }
                   8964: 
1.136     brouard  8965: #ifdef GSL
                   8966: /******************* Gompertz_f Likelihood ******************************/
                   8967: double gompertz_f(const gsl_vector *v, void *params)
                   8968: { 
                   8969:   double A,B,LL=0.0,sump=0.,num=0.;
                   8970:   double *x= (double *) v->data;
                   8971:   int i,n=0; /* n is the size of the sample */
                   8972: 
                   8973:   for (i=0;i<=imx-1 ; i++) {
                   8974:     sump=sump+weight[i];
                   8975:     /*    sump=sump+1;*/
                   8976:     num=num+1;
                   8977:   }
                   8978:  
                   8979:  
                   8980:   /* for (i=0; i<=imx; i++) 
                   8981:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8982:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8983:   for (i=1;i<=imx ; i++)
                   8984:     {
                   8985:       if (cens[i] == 1 && wav[i]>1)
                   8986:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8987:       
                   8988:       if (cens[i] == 0 && wav[i]>1)
                   8989:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8990:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8991:       
                   8992:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8993:       if (wav[i] > 1 ) { /* ??? */
                   8994:        LL=LL+A*weight[i];
                   8995:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8996:       }
                   8997:     }
                   8998: 
                   8999:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9000:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9001:  
                   9002:   return -2*LL*num/sump;
                   9003: }
                   9004: #endif
                   9005: 
1.126     brouard  9006: /******************* Printing html file ***********/
1.201     brouard  9007: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9008:                  int lastpass, int stepm, int weightopt, char model[],\
                   9009:                  int imx,  double p[],double **matcov,double agemortsup){
                   9010:   int i,k;
                   9011: 
                   9012:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9013:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9014:   for (i=1;i<=2;i++) 
                   9015:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9016:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9017:   fprintf(fichtm,"</ul>");
                   9018: 
                   9019: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9020: 
                   9021:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9022: 
                   9023:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9024:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9025: 
                   9026:  
                   9027:   fflush(fichtm);
                   9028: }
                   9029: 
                   9030: /******************* Gnuplot file **************/
1.201     brouard  9031: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9032: 
                   9033:   char dirfileres[132],optfileres[132];
1.164     brouard  9034: 
1.126     brouard  9035:   int ng;
                   9036: 
                   9037: 
                   9038:   /*#ifdef windows */
                   9039:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9040:     /*#endif */
                   9041: 
                   9042: 
                   9043:   strcpy(dirfileres,optionfilefiname);
                   9044:   strcpy(optfileres,"vpl");
1.199     brouard  9045:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9046:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9047:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9048:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9049:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9050: 
                   9051: } 
                   9052: 
1.136     brouard  9053: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9054: {
1.126     brouard  9055: 
1.136     brouard  9056:   /*-------- data file ----------*/
                   9057:   FILE *fic;
                   9058:   char dummy[]="                         ";
1.240     brouard  9059:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9060:   int lstra;
1.136     brouard  9061:   int linei, month, year,iout;
                   9062:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9063:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9064:   char *stratrunc;
1.223     brouard  9065: 
1.240     brouard  9066:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9067:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9068: 
1.240     brouard  9069:   for(v=1; v <=ncovcol;v++){
                   9070:     DummyV[v]=0;
                   9071:     FixedV[v]=0;
                   9072:   }
                   9073:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9074:     DummyV[v]=1;
                   9075:     FixedV[v]=0;
                   9076:   }
                   9077:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9078:     DummyV[v]=0;
                   9079:     FixedV[v]=1;
                   9080:   }
                   9081:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9082:     DummyV[v]=1;
                   9083:     FixedV[v]=1;
                   9084:   }
                   9085:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9086:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9087:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9088:   }
1.126     brouard  9089: 
1.136     brouard  9090:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9091:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9092:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9093:   }
1.126     brouard  9094: 
1.136     brouard  9095:   i=1;
                   9096:   linei=0;
                   9097:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9098:     linei=linei+1;
                   9099:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9100:       if(line[j] == '\t')
                   9101:        line[j] = ' ';
                   9102:     }
                   9103:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9104:       ;
                   9105:     };
                   9106:     line[j+1]=0;  /* Trims blanks at end of line */
                   9107:     if(line[0]=='#'){
                   9108:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9109:       printf("Comment line\n%s\n",line);
                   9110:       continue;
                   9111:     }
                   9112:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9113:     strcpy(line, linetmp);
1.223     brouard  9114:     
                   9115:     /* Loops on waves */
                   9116:     for (j=maxwav;j>=1;j--){
                   9117:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9118:        cutv(stra, strb, line, ' '); 
                   9119:        if(strb[0]=='.') { /* Missing value */
                   9120:          lval=-1;
                   9121:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9122:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9123:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9124:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9125:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9126:            return 1;
                   9127:          }
                   9128:        }else{
                   9129:          errno=0;
                   9130:          /* what_kind_of_number(strb); */
                   9131:          dval=strtod(strb,&endptr); 
                   9132:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9133:          /* if(strb != endptr && *endptr == '\0') */
                   9134:          /*    dval=dlval; */
                   9135:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9136:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9137:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9138:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9139:            return 1;
                   9140:          }
                   9141:          cotqvar[j][iv][i]=dval; 
                   9142:          cotvar[j][ntv+iv][i]=dval; 
                   9143:        }
                   9144:        strcpy(line,stra);
1.223     brouard  9145:       }/* end loop ntqv */
1.225     brouard  9146:       
1.223     brouard  9147:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9148:        cutv(stra, strb, line, ' '); 
                   9149:        if(strb[0]=='.') { /* Missing value */
                   9150:          lval=-1;
                   9151:        }else{
                   9152:          errno=0;
                   9153:          lval=strtol(strb,&endptr,10); 
                   9154:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9155:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9156:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9157:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9158:            return 1;
                   9159:          }
                   9160:        }
                   9161:        if(lval <-1 || lval >1){
                   9162:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9163:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9164:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9165:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9166:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9167:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9168:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9169:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9170:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9171:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9172:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9173:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9174:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9175:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9176:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9177:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9178:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9179:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9180:          return 1;
                   9181:        }
                   9182:        cotvar[j][iv][i]=(double)(lval);
                   9183:        strcpy(line,stra);
1.223     brouard  9184:       }/* end loop ntv */
1.225     brouard  9185:       
1.223     brouard  9186:       /* Statuses  at wave */
1.137     brouard  9187:       cutv(stra, strb, line, ' '); 
1.223     brouard  9188:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9189:        lval=-1;
1.136     brouard  9190:       }else{
1.238     brouard  9191:        errno=0;
                   9192:        lval=strtol(strb,&endptr,10); 
                   9193:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9194:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9195:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9196:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9197:          return 1;
                   9198:        }
1.136     brouard  9199:       }
1.225     brouard  9200:       
1.136     brouard  9201:       s[j][i]=lval;
1.225     brouard  9202:       
1.223     brouard  9203:       /* Date of Interview */
1.136     brouard  9204:       strcpy(line,stra);
                   9205:       cutv(stra, strb,line,' ');
1.169     brouard  9206:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9207:       }
1.169     brouard  9208:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9209:        month=99;
                   9210:        year=9999;
1.136     brouard  9211:       }else{
1.225     brouard  9212:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9213:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9214:        return 1;
1.136     brouard  9215:       }
                   9216:       anint[j][i]= (double) year; 
                   9217:       mint[j][i]= (double)month; 
                   9218:       strcpy(line,stra);
1.223     brouard  9219:     } /* End loop on waves */
1.225     brouard  9220:     
1.223     brouard  9221:     /* Date of death */
1.136     brouard  9222:     cutv(stra, strb,line,' '); 
1.169     brouard  9223:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9224:     }
1.169     brouard  9225:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9226:       month=99;
                   9227:       year=9999;
                   9228:     }else{
1.141     brouard  9229:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9230:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9231:       return 1;
1.136     brouard  9232:     }
                   9233:     andc[i]=(double) year; 
                   9234:     moisdc[i]=(double) month; 
                   9235:     strcpy(line,stra);
                   9236:     
1.223     brouard  9237:     /* Date of birth */
1.136     brouard  9238:     cutv(stra, strb,line,' '); 
1.169     brouard  9239:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9240:     }
1.169     brouard  9241:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9242:       month=99;
                   9243:       year=9999;
                   9244:     }else{
1.141     brouard  9245:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9246:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9247:       return 1;
1.136     brouard  9248:     }
                   9249:     if (year==9999) {
1.141     brouard  9250:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9251:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9252:       return 1;
                   9253:       
1.136     brouard  9254:     }
                   9255:     annais[i]=(double)(year);
                   9256:     moisnais[i]=(double)(month); 
                   9257:     strcpy(line,stra);
1.225     brouard  9258:     
1.223     brouard  9259:     /* Sample weight */
1.136     brouard  9260:     cutv(stra, strb,line,' '); 
                   9261:     errno=0;
                   9262:     dval=strtod(strb,&endptr); 
                   9263:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9264:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9265:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9266:       fflush(ficlog);
                   9267:       return 1;
                   9268:     }
                   9269:     weight[i]=dval; 
                   9270:     strcpy(line,stra);
1.225     brouard  9271:     
1.223     brouard  9272:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9273:       cutv(stra, strb, line, ' '); 
                   9274:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9275:        lval=-1;
1.223     brouard  9276:       }else{
1.225     brouard  9277:        errno=0;
                   9278:        /* what_kind_of_number(strb); */
                   9279:        dval=strtod(strb,&endptr);
                   9280:        /* if(strb != endptr && *endptr == '\0') */
                   9281:        /*   dval=dlval; */
                   9282:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9283:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9284:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9285:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9286:          return 1;
                   9287:        }
                   9288:        coqvar[iv][i]=dval; 
1.226     brouard  9289:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9290:       }
                   9291:       strcpy(line,stra);
                   9292:     }/* end loop nqv */
1.136     brouard  9293:     
1.223     brouard  9294:     /* Covariate values */
1.136     brouard  9295:     for (j=ncovcol;j>=1;j--){
                   9296:       cutv(stra, strb,line,' '); 
1.223     brouard  9297:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9298:        lval=-1;
1.136     brouard  9299:       }else{
1.225     brouard  9300:        errno=0;
                   9301:        lval=strtol(strb,&endptr,10); 
                   9302:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9303:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9304:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9305:          return 1;
                   9306:        }
1.136     brouard  9307:       }
                   9308:       if(lval <-1 || lval >1){
1.225     brouard  9309:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9310:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9311:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9312:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9313:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9314:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9315:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9316:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9317:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9318:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9319:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9320:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9321:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9322:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9323:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9324:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9325:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9326:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9327:        return 1;
1.136     brouard  9328:       }
                   9329:       covar[j][i]=(double)(lval);
                   9330:       strcpy(line,stra);
                   9331:     }  
                   9332:     lstra=strlen(stra);
1.225     brouard  9333:     
1.136     brouard  9334:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9335:       stratrunc = &(stra[lstra-9]);
                   9336:       num[i]=atol(stratrunc);
                   9337:     }
                   9338:     else
                   9339:       num[i]=atol(stra);
                   9340:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9341:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9342:     
                   9343:     i=i+1;
                   9344:   } /* End loop reading  data */
1.225     brouard  9345:   
1.136     brouard  9346:   *imax=i-1; /* Number of individuals */
                   9347:   fclose(fic);
1.225     brouard  9348:   
1.136     brouard  9349:   return (0);
1.164     brouard  9350:   /* endread: */
1.225     brouard  9351:   printf("Exiting readdata: ");
                   9352:   fclose(fic);
                   9353:   return (1);
1.223     brouard  9354: }
1.126     brouard  9355: 
1.234     brouard  9356: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9357:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9358:   while (*p2 == ' ')
1.234     brouard  9359:     p2++; 
                   9360:   /* while ((*p1++ = *p2++) !=0) */
                   9361:   /*   ; */
                   9362:   /* do */
                   9363:   /*   while (*p2 == ' ') */
                   9364:   /*     p2++; */
                   9365:   /* while (*p1++ == *p2++); */
                   9366:   *stri=p2; 
1.145     brouard  9367: }
                   9368: 
1.235     brouard  9369: int decoderesult ( char resultline[], int nres)
1.230     brouard  9370: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9371: {
1.235     brouard  9372:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9373:   char resultsav[MAXLINE];
1.234     brouard  9374:   int resultmodel[MAXLINE];
                   9375:   int modelresult[MAXLINE];
1.230     brouard  9376:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9377: 
1.234     brouard  9378:   removefirstspace(&resultline);
1.233     brouard  9379:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9380: 
                   9381:   if (strstr(resultline,"v") !=0){
                   9382:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9383:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9384:     return 1;
                   9385:   }
                   9386:   trimbb(resultsav, resultline);
                   9387:   if (strlen(resultsav) >1){
                   9388:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9389:   }
1.253     brouard  9390:   if(j == 0){ /* Resultline but no = */
                   9391:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9392:     return (0);
                   9393:   }
                   9394:     
1.234     brouard  9395:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9396:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9397:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9398:   }
                   9399:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9400:     if(nbocc(resultsav,'=') >1){
                   9401:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9402:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9403:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9404:     }else
                   9405:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9406:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9407:     
1.230     brouard  9408:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9409:     Tvarsel[k]=atoi(strc);
                   9410:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9411:     /* cptcovsel++;     */
                   9412:     if (nbocc(stra,'=') >0)
                   9413:       strcpy(resultsav,stra); /* and analyzes it */
                   9414:   }
1.235     brouard  9415:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9416:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9417:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9418:       match=0;
1.236     brouard  9419:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9420:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9421:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9422:          match=1;
                   9423:          break;
                   9424:        }
                   9425:       }
                   9426:       if(match == 0){
                   9427:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9428:       }
                   9429:     }
                   9430:   }
1.235     brouard  9431:   /* Checking for missing or useless values in comparison of current model needs */
                   9432:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9433:     match=0;
1.235     brouard  9434:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9435:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9436:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9437:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9438:          ++match;
                   9439:        }
                   9440:       }
                   9441:     }
                   9442:     if(match == 0){
                   9443:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9444:     }else if(match > 1){
                   9445:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9446:     }
                   9447:   }
1.235     brouard  9448:       
1.234     brouard  9449:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9450:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9451:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9452:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9453:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9454:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9455:   /*    1 0 0 0 */
                   9456:   /*    2 1 0 0 */
                   9457:   /*    3 0 1 0 */ 
                   9458:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9459:   /*    5 0 0 1 */
                   9460:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9461:   /*    7 0 1 1 */
                   9462:   /*    8 1 1 1 */
1.237     brouard  9463:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9464:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9465:   /* V5*age V5 known which value for nres?  */
                   9466:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9467:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9468:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9469:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9470:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9471:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9472:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9473:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9474:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9475:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9476:       k4++;;
                   9477:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9478:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9479:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9480:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9481:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9482:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9483:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9484:       k4q++;;
                   9485:     }
                   9486:   }
1.234     brouard  9487:   
1.235     brouard  9488:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9489:   return (0);
                   9490: }
1.235     brouard  9491: 
1.230     brouard  9492: int decodemodel( char model[], int lastobs)
                   9493:  /**< This routine decodes the model and returns:
1.224     brouard  9494:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9495:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9496:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9497:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9498:        * - cptcovage number of covariates with age*products =2
                   9499:        * - cptcovs number of simple covariates
                   9500:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9501:        *     which is a new column after the 9 (ncovcol) variables. 
                   9502:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9503:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9504:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9505:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9506:        */
1.136     brouard  9507: {
1.238     brouard  9508:   int i, j, k, ks, v;
1.227     brouard  9509:   int  j1, k1, k2, k3, k4;
1.136     brouard  9510:   char modelsav[80];
1.145     brouard  9511:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9512:   char *strpt;
1.136     brouard  9513: 
1.145     brouard  9514:   /*removespace(model);*/
1.136     brouard  9515:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9516:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9517:     if (strstr(model,"AGE") !=0){
1.192     brouard  9518:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9519:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9520:       return 1;
                   9521:     }
1.141     brouard  9522:     if (strstr(model,"v") !=0){
                   9523:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9524:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9525:       return 1;
                   9526:     }
1.187     brouard  9527:     strcpy(modelsav,model); 
                   9528:     if ((strpt=strstr(model,"age*age")) !=0){
                   9529:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9530:       if(strpt != model){
1.234     brouard  9531:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9532:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9533:  corresponding column of parameters.\n",model);
1.234     brouard  9534:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9535:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9536:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9537:        return 1;
1.225     brouard  9538:       }
1.187     brouard  9539:       nagesqr=1;
                   9540:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9541:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9542:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9543:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9544:       else 
1.234     brouard  9545:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9546:     }else
                   9547:       nagesqr=0;
                   9548:     if (strlen(modelsav) >1){
                   9549:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9550:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9551:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9552:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9553:                     * cst, age and age*age 
                   9554:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9555:       /* including age products which are counted in cptcovage.
                   9556:        * but the covariates which are products must be treated 
                   9557:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9558:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9559:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9560:       
                   9561:       
1.187     brouard  9562:       /*   Design
                   9563:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9564:        *  <          ncovcol=8                >
                   9565:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9566:        *   k=  1    2      3       4     5       6      7        8
                   9567:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9568:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9569:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9570:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9571:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9572:        *  Tage[++cptcovage]=k
                   9573:        *       if products, new covar are created after ncovcol with k1
                   9574:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9575:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9576:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9577:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9578:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9579:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9580:        *  <          ncovcol=8                >
                   9581:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9582:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9583:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9584:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9585:        * p Tprod[1]@2={                         6, 5}
                   9586:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9587:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9588:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9589:        *How to reorganize?
                   9590:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9591:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9592:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9593:        * Struct []
                   9594:        */
1.225     brouard  9595:       
1.187     brouard  9596:       /* This loop fills the array Tvar from the string 'model'.*/
                   9597:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9598:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9599:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9600:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9601:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9602:       /*       k=1 Tvar[1]=2 (from V2) */
                   9603:       /*       k=5 Tvar[5] */
                   9604:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9605:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9606:       /*       } */
1.198     brouard  9607:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9608:       /*
                   9609:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9610:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9611:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9612:       }
1.187     brouard  9613:       cptcovage=0;
                   9614:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9615:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9616:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9617:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9618:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9619:        /*scanf("%d",i);*/
                   9620:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9621:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9622:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9623:            /* covar is not filled and then is empty */
                   9624:            cptcovprod--;
                   9625:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9626:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9627:            Typevar[k]=1;  /* 1 for age product */
                   9628:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9629:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9630:            /*printf("stre=%s ", stre);*/
                   9631:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9632:            cptcovprod--;
                   9633:            cutl(stre,strb,strc,'V');
                   9634:            Tvar[k]=atoi(stre);
                   9635:            Typevar[k]=1;  /* 1 for age product */
                   9636:            cptcovage++;
                   9637:            Tage[cptcovage]=k;
                   9638:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9639:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9640:            cptcovn++;
                   9641:            cptcovprodnoage++;k1++;
                   9642:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9643:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9644:                                                because this model-covariate is a construction we invent a new column
                   9645:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9646:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9647:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9648:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9649:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9650:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9651:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9652:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9653:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9654:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9655:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9656:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9657:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9658:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9659:            for (i=1; i<=lastobs;i++){
                   9660:              /* Computes the new covariate which is a product of
                   9661:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9662:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9663:            }
                   9664:          } /* End age is not in the model */
                   9665:        } /* End if model includes a product */
                   9666:        else { /* no more sum */
                   9667:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9668:          /*  scanf("%d",i);*/
                   9669:          cutl(strd,strc,strb,'V');
                   9670:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9671:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9672:          Tvar[k]=atoi(strd);
                   9673:          Typevar[k]=0;  /* 0 for simple covariates */
                   9674:        }
                   9675:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9676:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9677:                                  scanf("%d",i);*/
1.187     brouard  9678:       } /* end of loop + on total covariates */
                   9679:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9680:   } /* end if strlen(model == 0) */
1.136     brouard  9681:   
                   9682:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9683:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9684:   
1.136     brouard  9685:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9686:      printf("cptcovprod=%d ", cptcovprod);
                   9687:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9688:      scanf("%d ",i);*/
                   9689: 
                   9690: 
1.230     brouard  9691: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9692:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9693: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9694:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9695:    k =           1    2   3     4       5       6      7      8        9
                   9696:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9697:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9698:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9699:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9700:          Tmodelind[combination of covar]=k;
1.225     brouard  9701: */  
                   9702: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9703:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9704:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9705:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9706:   printf("Model=%s\n\
                   9707: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9708: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9709: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9710:   fprintf(ficlog,"Model=%s\n\
                   9711: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9712: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9713: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9714:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9715:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9716:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9717:       Fixed[k]= 0;
                   9718:       Dummy[k]= 0;
1.225     brouard  9719:       ncoveff++;
1.232     brouard  9720:       ncovf++;
1.234     brouard  9721:       nsd++;
                   9722:       modell[k].maintype= FTYPE;
                   9723:       TvarsD[nsd]=Tvar[k];
                   9724:       TvarsDind[nsd]=k;
                   9725:       TvarF[ncovf]=Tvar[k];
                   9726:       TvarFind[ncovf]=k;
                   9727:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9728:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9729:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9730:       Fixed[k]= 0;
                   9731:       Dummy[k]= 0;
                   9732:       ncoveff++;
                   9733:       ncovf++;
                   9734:       modell[k].maintype= FTYPE;
                   9735:       TvarF[ncovf]=Tvar[k];
                   9736:       TvarFind[ncovf]=k;
1.230     brouard  9737:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9738:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9739:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9740:       Fixed[k]= 0;
                   9741:       Dummy[k]= 1;
1.230     brouard  9742:       nqfveff++;
1.234     brouard  9743:       modell[k].maintype= FTYPE;
                   9744:       modell[k].subtype= FQ;
                   9745:       nsq++;
                   9746:       TvarsQ[nsq]=Tvar[k];
                   9747:       TvarsQind[nsq]=k;
1.232     brouard  9748:       ncovf++;
1.234     brouard  9749:       TvarF[ncovf]=Tvar[k];
                   9750:       TvarFind[ncovf]=k;
1.231     brouard  9751:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9752:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9753:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9754:       Fixed[k]= 1;
                   9755:       Dummy[k]= 0;
1.225     brouard  9756:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9757:       modell[k].maintype= VTYPE;
                   9758:       modell[k].subtype= VD;
                   9759:       nsd++;
                   9760:       TvarsD[nsd]=Tvar[k];
                   9761:       TvarsDind[nsd]=k;
                   9762:       ncovv++; /* Only simple time varying variables */
                   9763:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9764:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9765:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9766:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9767:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9768:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9769:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9770:       Fixed[k]= 1;
                   9771:       Dummy[k]= 1;
                   9772:       nqtveff++;
                   9773:       modell[k].maintype= VTYPE;
                   9774:       modell[k].subtype= VQ;
                   9775:       ncovv++; /* Only simple time varying variables */
                   9776:       nsq++;
                   9777:       TvarsQ[nsq]=Tvar[k];
                   9778:       TvarsQind[nsq]=k;
                   9779:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9780:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9781:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9782:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9783:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9784:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9785:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9786:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9787:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9788:       ncova++;
                   9789:       TvarA[ncova]=Tvar[k];
                   9790:       TvarAind[ncova]=k;
1.231     brouard  9791:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9792:        Fixed[k]= 2;
                   9793:        Dummy[k]= 2;
                   9794:        modell[k].maintype= ATYPE;
                   9795:        modell[k].subtype= APFD;
                   9796:        /* ncoveff++; */
1.227     brouard  9797:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9798:        Fixed[k]= 2;
                   9799:        Dummy[k]= 3;
                   9800:        modell[k].maintype= ATYPE;
                   9801:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9802:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9803:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9804:        Fixed[k]= 3;
                   9805:        Dummy[k]= 2;
                   9806:        modell[k].maintype= ATYPE;
                   9807:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9808:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9809:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9810:        Fixed[k]= 3;
                   9811:        Dummy[k]= 3;
                   9812:        modell[k].maintype= ATYPE;
                   9813:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9814:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9815:       }
                   9816:     }else if (Typevar[k] == 2) {  /* product without age */
                   9817:       k1=Tposprod[k];
                   9818:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9819:        if(Tvard[k1][2] <=ncovcol){
                   9820:          Fixed[k]= 1;
                   9821:          Dummy[k]= 0;
                   9822:          modell[k].maintype= FTYPE;
                   9823:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9824:          ncovf++; /* Fixed variables without age */
                   9825:          TvarF[ncovf]=Tvar[k];
                   9826:          TvarFind[ncovf]=k;
                   9827:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9828:          Fixed[k]= 0;  /* or 2 ?*/
                   9829:          Dummy[k]= 1;
                   9830:          modell[k].maintype= FTYPE;
                   9831:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9832:          ncovf++; /* Varying variables without age */
                   9833:          TvarF[ncovf]=Tvar[k];
                   9834:          TvarFind[ncovf]=k;
                   9835:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9836:          Fixed[k]= 1;
                   9837:          Dummy[k]= 0;
                   9838:          modell[k].maintype= VTYPE;
                   9839:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9840:          ncovv++; /* Varying variables without age */
                   9841:          TvarV[ncovv]=Tvar[k];
                   9842:          TvarVind[ncovv]=k;
                   9843:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9844:          Fixed[k]= 1;
                   9845:          Dummy[k]= 1;
                   9846:          modell[k].maintype= VTYPE;
                   9847:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9848:          ncovv++; /* Varying variables without age */
                   9849:          TvarV[ncovv]=Tvar[k];
                   9850:          TvarVind[ncovv]=k;
                   9851:        }
1.227     brouard  9852:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9853:        if(Tvard[k1][2] <=ncovcol){
                   9854:          Fixed[k]= 0;  /* or 2 ?*/
                   9855:          Dummy[k]= 1;
                   9856:          modell[k].maintype= FTYPE;
                   9857:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9858:          ncovf++; /* Fixed variables without age */
                   9859:          TvarF[ncovf]=Tvar[k];
                   9860:          TvarFind[ncovf]=k;
                   9861:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9862:          Fixed[k]= 1;
                   9863:          Dummy[k]= 1;
                   9864:          modell[k].maintype= VTYPE;
                   9865:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9866:          ncovv++; /* Varying variables without age */
                   9867:          TvarV[ncovv]=Tvar[k];
                   9868:          TvarVind[ncovv]=k;
                   9869:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9870:          Fixed[k]= 1;
                   9871:          Dummy[k]= 1;
                   9872:          modell[k].maintype= VTYPE;
                   9873:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9874:          ncovv++; /* Varying variables without age */
                   9875:          TvarV[ncovv]=Tvar[k];
                   9876:          TvarVind[ncovv]=k;
                   9877:          ncovv++; /* Varying variables without age */
                   9878:          TvarV[ncovv]=Tvar[k];
                   9879:          TvarVind[ncovv]=k;
                   9880:        }
1.227     brouard  9881:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9882:        if(Tvard[k1][2] <=ncovcol){
                   9883:          Fixed[k]= 1;
                   9884:          Dummy[k]= 1;
                   9885:          modell[k].maintype= VTYPE;
                   9886:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9887:          ncovv++; /* Varying variables without age */
                   9888:          TvarV[ncovv]=Tvar[k];
                   9889:          TvarVind[ncovv]=k;
                   9890:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9891:          Fixed[k]= 1;
                   9892:          Dummy[k]= 1;
                   9893:          modell[k].maintype= VTYPE;
                   9894:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9895:          ncovv++; /* Varying variables without age */
                   9896:          TvarV[ncovv]=Tvar[k];
                   9897:          TvarVind[ncovv]=k;
                   9898:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9899:          Fixed[k]= 1;
                   9900:          Dummy[k]= 0;
                   9901:          modell[k].maintype= VTYPE;
                   9902:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9903:          ncovv++; /* Varying variables without age */
                   9904:          TvarV[ncovv]=Tvar[k];
                   9905:          TvarVind[ncovv]=k;
                   9906:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9907:          Fixed[k]= 1;
                   9908:          Dummy[k]= 1;
                   9909:          modell[k].maintype= VTYPE;
                   9910:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9911:          ncovv++; /* Varying variables without age */
                   9912:          TvarV[ncovv]=Tvar[k];
                   9913:          TvarVind[ncovv]=k;
                   9914:        }
1.227     brouard  9915:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9916:        if(Tvard[k1][2] <=ncovcol){
                   9917:          Fixed[k]= 1;
                   9918:          Dummy[k]= 1;
                   9919:          modell[k].maintype= VTYPE;
                   9920:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9921:          ncovv++; /* Varying variables without age */
                   9922:          TvarV[ncovv]=Tvar[k];
                   9923:          TvarVind[ncovv]=k;
                   9924:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9925:          Fixed[k]= 1;
                   9926:          Dummy[k]= 1;
                   9927:          modell[k].maintype= VTYPE;
                   9928:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9929:          ncovv++; /* Varying variables without age */
                   9930:          TvarV[ncovv]=Tvar[k];
                   9931:          TvarVind[ncovv]=k;
                   9932:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9933:          Fixed[k]= 1;
                   9934:          Dummy[k]= 1;
                   9935:          modell[k].maintype= VTYPE;
                   9936:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9937:          ncovv++; /* Varying variables without age */
                   9938:          TvarV[ncovv]=Tvar[k];
                   9939:          TvarVind[ncovv]=k;
                   9940:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9941:          Fixed[k]= 1;
                   9942:          Dummy[k]= 1;
                   9943:          modell[k].maintype= VTYPE;
                   9944:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9945:          ncovv++; /* Varying variables without age */
                   9946:          TvarV[ncovv]=Tvar[k];
                   9947:          TvarVind[ncovv]=k;
                   9948:        }
1.227     brouard  9949:       }else{
1.240     brouard  9950:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9951:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9952:       } /*end k1*/
1.225     brouard  9953:     }else{
1.226     brouard  9954:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9955:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9956:     }
1.227     brouard  9957:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9958:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9959:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9960:   }
                   9961:   /* Searching for doublons in the model */
                   9962:   for(k1=1; k1<= cptcovt;k1++){
                   9963:     for(k2=1; k2 <k1;k2++){
                   9964:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9965:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9966:          if(Tvar[k1]==Tvar[k2]){
                   9967:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9968:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9969:            return(1);
                   9970:          }
                   9971:        }else if (Typevar[k1] ==2){
                   9972:          k3=Tposprod[k1];
                   9973:          k4=Tposprod[k2];
                   9974:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9975:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9976:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9977:            return(1);
                   9978:          }
                   9979:        }
1.227     brouard  9980:       }
                   9981:     }
1.225     brouard  9982:   }
                   9983:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9984:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9985:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9986:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9987:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9988:   /*endread:*/
1.225     brouard  9989:   printf("Exiting decodemodel: ");
                   9990:   return (1);
1.136     brouard  9991: }
                   9992: 
1.169     brouard  9993: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9994: {/* Check ages at death */
1.136     brouard  9995:   int i, m;
1.218     brouard  9996:   int firstone=0;
                   9997:   
1.136     brouard  9998:   for (i=1; i<=imx; i++) {
                   9999:     for(m=2; (m<= maxwav); m++) {
                   10000:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10001:        anint[m][i]=9999;
1.216     brouard  10002:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10003:          s[m][i]=-1;
1.136     brouard  10004:       }
                   10005:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10006:        *nberr = *nberr + 1;
1.218     brouard  10007:        if(firstone == 0){
                   10008:          firstone=1;
1.260     brouard  10009:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10010:        }
1.262     brouard  10011:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10012:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10013:       }
                   10014:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10015:        (*nberr)++;
1.259     brouard  10016:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10017:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10018:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10019:       }
                   10020:     }
                   10021:   }
                   10022: 
                   10023:   for (i=1; i<=imx; i++)  {
                   10024:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10025:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10026:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10027:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10028:          if(agedc[i]>0){
                   10029:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10030:              agev[m][i]=agedc[i];
1.214     brouard  10031:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10032:            }else {
1.136     brouard  10033:              if ((int)andc[i]!=9999){
                   10034:                nbwarn++;
                   10035:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10036:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10037:                agev[m][i]=-1;
                   10038:              }
                   10039:            }
1.169     brouard  10040:          } /* agedc > 0 */
1.214     brouard  10041:        } /* end if */
1.136     brouard  10042:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10043:                                 years but with the precision of a month */
                   10044:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10045:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10046:            agev[m][i]=1;
                   10047:          else if(agev[m][i] < *agemin){ 
                   10048:            *agemin=agev[m][i];
                   10049:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10050:          }
                   10051:          else if(agev[m][i] >*agemax){
                   10052:            *agemax=agev[m][i];
1.156     brouard  10053:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10054:          }
                   10055:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10056:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10057:        } /* en if 9*/
1.136     brouard  10058:        else { /* =9 */
1.214     brouard  10059:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10060:          agev[m][i]=1;
                   10061:          s[m][i]=-1;
                   10062:        }
                   10063:       }
1.214     brouard  10064:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10065:        agev[m][i]=1;
1.214     brouard  10066:       else{
                   10067:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10068:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10069:        agev[m][i]=0;
                   10070:       }
                   10071:     } /* End for lastpass */
                   10072:   }
1.136     brouard  10073:     
                   10074:   for (i=1; i<=imx; i++)  {
                   10075:     for(m=firstpass; (m<=lastpass); m++){
                   10076:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10077:        (*nberr)++;
1.136     brouard  10078:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10079:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10080:        return 1;
                   10081:       }
                   10082:     }
                   10083:   }
                   10084: 
                   10085:   /*for (i=1; i<=imx; i++){
                   10086:   for (m=firstpass; (m<lastpass); m++){
                   10087:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10088: }
                   10089: 
                   10090: }*/
                   10091: 
                   10092: 
1.139     brouard  10093:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10094:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10095: 
                   10096:   return (0);
1.164     brouard  10097:  /* endread:*/
1.136     brouard  10098:     printf("Exiting calandcheckages: ");
                   10099:     return (1);
                   10100: }
                   10101: 
1.172     brouard  10102: #if defined(_MSC_VER)
                   10103: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10104: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10105: //#include "stdafx.h"
                   10106: //#include <stdio.h>
                   10107: //#include <tchar.h>
                   10108: //#include <windows.h>
                   10109: //#include <iostream>
                   10110: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10111: 
                   10112: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10113: 
                   10114: BOOL IsWow64()
                   10115: {
                   10116:        BOOL bIsWow64 = FALSE;
                   10117: 
                   10118:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10119:        //  (HANDLE, PBOOL);
                   10120: 
                   10121:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10122: 
                   10123:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10124:        const char funcName[] = "IsWow64Process";
                   10125:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10126:                GetProcAddress(module, funcName);
                   10127: 
                   10128:        if (NULL != fnIsWow64Process)
                   10129:        {
                   10130:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10131:                        &bIsWow64))
                   10132:                        //throw std::exception("Unknown error");
                   10133:                        printf("Unknown error\n");
                   10134:        }
                   10135:        return bIsWow64 != FALSE;
                   10136: }
                   10137: #endif
1.177     brouard  10138: 
1.191     brouard  10139: void syscompilerinfo(int logged)
1.167     brouard  10140:  {
                   10141:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10142:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10143:    /* /GS /W3 /Gy
                   10144:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10145:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10146:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10147:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10148:    */ 
                   10149:    /* 64 bits */
1.185     brouard  10150:    /*
                   10151:      /GS /W3 /Gy
                   10152:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10153:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10154:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10155:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10156:    /* Optimization are useless and O3 is slower than O2 */
                   10157:    /*
                   10158:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10159:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10160:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10161:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10162:    */
1.186     brouard  10163:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10164:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10165:       /PDB:"visual studio
                   10166:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10167:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10168:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10169:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10170:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10171:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10172:       uiAccess='false'"
                   10173:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10174:       /NOLOGO /TLBID:1
                   10175:    */
1.177     brouard  10176: #if defined __INTEL_COMPILER
1.178     brouard  10177: #if defined(__GNUC__)
                   10178:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10179: #endif
1.177     brouard  10180: #elif defined(__GNUC__) 
1.179     brouard  10181: #ifndef  __APPLE__
1.174     brouard  10182: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10183: #endif
1.177     brouard  10184:    struct utsname sysInfo;
1.178     brouard  10185:    int cross = CROSS;
                   10186:    if (cross){
                   10187:           printf("Cross-");
1.191     brouard  10188:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10189:    }
1.174     brouard  10190: #endif
                   10191: 
1.171     brouard  10192: #include <stdint.h>
1.178     brouard  10193: 
1.191     brouard  10194:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10195: #if defined(__clang__)
1.191     brouard  10196:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10197: #endif
                   10198: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10199:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10200: #endif
                   10201: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10202:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10203: #endif
                   10204: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10205:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10206: #endif
                   10207: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10208:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10209: #endif
                   10210: #if defined(_MSC_VER)
1.191     brouard  10211:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10212: #endif
                   10213: #if defined(__PGI)
1.191     brouard  10214:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10215: #endif
                   10216: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10217:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10218: #endif
1.191     brouard  10219:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10220:    
1.167     brouard  10221: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10222: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10223:     // Windows (x64 and x86)
1.191     brouard  10224:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10225: #elif __unix__ // all unices, not all compilers
                   10226:     // Unix
1.191     brouard  10227:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10228: #elif __linux__
                   10229:     // linux
1.191     brouard  10230:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10231: #elif __APPLE__
1.174     brouard  10232:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10233:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10234: #endif
                   10235: 
                   10236: /*  __MINGW32__          */
                   10237: /*  __CYGWIN__  */
                   10238: /* __MINGW64__  */
                   10239: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10240: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10241: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10242: /* _WIN64  // Defined for applications for Win64. */
                   10243: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10244: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10245: 
1.167     brouard  10246: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10247:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10248: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10249:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10250: #else
1.191     brouard  10251:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10252: #endif
                   10253: 
1.169     brouard  10254: #if defined(__GNUC__)
                   10255: # if defined(__GNUC_PATCHLEVEL__)
                   10256: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10257:                             + __GNUC_MINOR__ * 100 \
                   10258:                             + __GNUC_PATCHLEVEL__)
                   10259: # else
                   10260: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10261:                             + __GNUC_MINOR__ * 100)
                   10262: # endif
1.174     brouard  10263:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10264:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10265: 
                   10266:    if (uname(&sysInfo) != -1) {
                   10267:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10268:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10269:    }
                   10270:    else
                   10271:       perror("uname() error");
1.179     brouard  10272:    //#ifndef __INTEL_COMPILER 
                   10273: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10274:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10275:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10276: #endif
1.169     brouard  10277: #endif
1.172     brouard  10278: 
                   10279:    //   void main()
                   10280:    //   {
1.169     brouard  10281: #if defined(_MSC_VER)
1.174     brouard  10282:    if (IsWow64()){
1.191     brouard  10283:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10284:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10285:    }
                   10286:    else{
1.191     brouard  10287:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10288:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10289:    }
1.172     brouard  10290:    //     printf("\nPress Enter to continue...");
                   10291:    //     getchar();
                   10292:    //   }
                   10293: 
1.169     brouard  10294: #endif
                   10295:    
1.167     brouard  10296: 
1.219     brouard  10297: }
1.136     brouard  10298: 
1.219     brouard  10299: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10300:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10301:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10302:   /* double ftolpl = 1.e-10; */
1.180     brouard  10303:   double age, agebase, agelim;
1.203     brouard  10304:   double tot;
1.180     brouard  10305: 
1.202     brouard  10306:   strcpy(filerespl,"PL_");
                   10307:   strcat(filerespl,fileresu);
                   10308:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10309:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10310:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10311:   }
1.227     brouard  10312:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10313:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10314:   pstamp(ficrespl);
1.203     brouard  10315:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10316:   fprintf(ficrespl,"#Age ");
                   10317:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10318:   fprintf(ficrespl,"\n");
1.180     brouard  10319:   
1.219     brouard  10320:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10321: 
1.219     brouard  10322:   agebase=ageminpar;
                   10323:   agelim=agemaxpar;
1.180     brouard  10324: 
1.227     brouard  10325:   /* i1=pow(2,ncoveff); */
1.234     brouard  10326:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10327:   if (cptcovn < 1){i1=1;}
1.180     brouard  10328: 
1.238     brouard  10329:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10330:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10331:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10332:        continue;
1.235     brouard  10333: 
1.238     brouard  10334:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10335:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10336:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10337:       /* k=k+1; */
                   10338:       /* to clean */
                   10339:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10340:       fprintf(ficrespl,"#******");
                   10341:       printf("#******");
                   10342:       fprintf(ficlog,"#******");
                   10343:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10344:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10345:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10346:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10347:       }
                   10348:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10349:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10350:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10351:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10352:       }
                   10353:       fprintf(ficrespl,"******\n");
                   10354:       printf("******\n");
                   10355:       fprintf(ficlog,"******\n");
                   10356:       if(invalidvarcomb[k]){
                   10357:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10358:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10359:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10360:        continue;
                   10361:       }
1.219     brouard  10362: 
1.238     brouard  10363:       fprintf(ficrespl,"#Age ");
                   10364:       for(j=1;j<=cptcoveff;j++) {
                   10365:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10366:       }
                   10367:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10368:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10369:     
1.238     brouard  10370:       for (age=agebase; age<=agelim; age++){
                   10371:        /* for (age=agebase; age<=agebase; age++){ */
                   10372:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10373:        fprintf(ficrespl,"%.0f ",age );
                   10374:        for(j=1;j<=cptcoveff;j++)
                   10375:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10376:        tot=0.;
                   10377:        for(i=1; i<=nlstate;i++){
                   10378:          tot +=  prlim[i][i];
                   10379:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10380:        }
                   10381:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10382:       } /* Age */
                   10383:       /* was end of cptcod */
                   10384:     } /* cptcov */
                   10385:   } /* nres */
1.219     brouard  10386:   return 0;
1.180     brouard  10387: }
                   10388: 
1.218     brouard  10389: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10390:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10391:        
                   10392:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10393:    * at any age between ageminpar and agemaxpar
                   10394:         */
1.235     brouard  10395:   int i, j, k, i1, nres=0 ;
1.217     brouard  10396:   /* double ftolpl = 1.e-10; */
                   10397:   double age, agebase, agelim;
                   10398:   double tot;
1.218     brouard  10399:   /* double ***mobaverage; */
                   10400:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10401: 
                   10402:   strcpy(fileresplb,"PLB_");
                   10403:   strcat(fileresplb,fileresu);
                   10404:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10405:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10406:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10407:   }
                   10408:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10409:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10410:   pstamp(ficresplb);
                   10411:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10412:   fprintf(ficresplb,"#Age ");
                   10413:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10414:   fprintf(ficresplb,"\n");
                   10415:   
1.218     brouard  10416:   
                   10417:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10418:   
                   10419:   agebase=ageminpar;
                   10420:   agelim=agemaxpar;
                   10421:   
                   10422:   
1.227     brouard  10423:   i1=pow(2,cptcoveff);
1.218     brouard  10424:   if (cptcovn < 1){i1=1;}
1.227     brouard  10425:   
1.238     brouard  10426:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10427:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10428:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10429:        continue;
                   10430:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10431:       fprintf(ficresplb,"#******");
                   10432:       printf("#******");
                   10433:       fprintf(ficlog,"#******");
                   10434:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10435:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10436:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10437:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10438:       }
                   10439:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10440:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10441:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10442:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10443:       }
                   10444:       fprintf(ficresplb,"******\n");
                   10445:       printf("******\n");
                   10446:       fprintf(ficlog,"******\n");
                   10447:       if(invalidvarcomb[k]){
                   10448:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10449:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10450:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10451:        continue;
                   10452:       }
1.218     brouard  10453:     
1.238     brouard  10454:       fprintf(ficresplb,"#Age ");
                   10455:       for(j=1;j<=cptcoveff;j++) {
                   10456:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10457:       }
                   10458:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10459:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10460:     
                   10461:     
1.238     brouard  10462:       for (age=agebase; age<=agelim; age++){
                   10463:        /* for (age=agebase; age<=agebase; age++){ */
                   10464:        if(mobilavproj > 0){
                   10465:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10466:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10467:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10468:        }else if (mobilavproj == 0){
                   10469:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10470:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10471:          exit(1);
                   10472:        }else{
                   10473:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10474:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10475:          /* printf("TOTOT\n"); */
                   10476:           /* exit(1); */
1.238     brouard  10477:        }
                   10478:        fprintf(ficresplb,"%.0f ",age );
                   10479:        for(j=1;j<=cptcoveff;j++)
                   10480:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10481:        tot=0.;
                   10482:        for(i=1; i<=nlstate;i++){
                   10483:          tot +=  bprlim[i][i];
                   10484:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10485:        }
                   10486:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10487:       } /* Age */
                   10488:       /* was end of cptcod */
1.255     brouard  10489:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10490:     } /* end of any combination */
                   10491:   } /* end of nres */  
1.218     brouard  10492:   /* hBijx(p, bage, fage); */
                   10493:   /* fclose(ficrespijb); */
                   10494:   
                   10495:   return 0;
1.217     brouard  10496: }
1.218     brouard  10497:  
1.180     brouard  10498: int hPijx(double *p, int bage, int fage){
                   10499:     /*------------- h Pij x at various ages ------------*/
                   10500: 
                   10501:   int stepsize;
                   10502:   int agelim;
                   10503:   int hstepm;
                   10504:   int nhstepm;
1.235     brouard  10505:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10506: 
                   10507:   double agedeb;
                   10508:   double ***p3mat;
                   10509: 
1.201     brouard  10510:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10511:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10512:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10513:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10514:     }
                   10515:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10516:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10517:   
                   10518:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10519:     /*if (stepm<=24) stepsize=2;*/
                   10520: 
                   10521:     agelim=AGESUP;
                   10522:     hstepm=stepsize*YEARM; /* Every year of age */
                   10523:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10524:                
1.180     brouard  10525:     /* hstepm=1;   aff par mois*/
                   10526:     pstamp(ficrespij);
                   10527:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10528:     i1= pow(2,cptcoveff);
1.218     brouard  10529:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10530:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10531:                /*      k=k+1;  */
1.235     brouard  10532:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10533:     for(k=1; k<=i1;k++){
1.253     brouard  10534:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10535:        continue;
1.183     brouard  10536:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10537:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10538:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10539:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10540:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10541:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10542:       }
1.183     brouard  10543:       fprintf(ficrespij,"******\n");
                   10544:       
                   10545:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10546:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10547:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10548:        
                   10549:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10550:        
1.183     brouard  10551:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10552:        oldm=oldms;savm=savms;
1.235     brouard  10553:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10554:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10555:        for(i=1; i<=nlstate;i++)
                   10556:          for(j=1; j<=nlstate+ndeath;j++)
                   10557:            fprintf(ficrespij," %1d-%1d",i,j);
                   10558:        fprintf(ficrespij,"\n");
                   10559:        for (h=0; h<=nhstepm; h++){
                   10560:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10561:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10562:          for(i=1; i<=nlstate;i++)
                   10563:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10564:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10565:          fprintf(ficrespij,"\n");
                   10566:        }
1.183     brouard  10567:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10568:        fprintf(ficrespij,"\n");
                   10569:       }
1.180     brouard  10570:       /*}*/
                   10571:     }
1.218     brouard  10572:     return 0;
1.180     brouard  10573: }
1.218     brouard  10574:  
                   10575:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10576:     /*------------- h Bij x at various ages ------------*/
                   10577: 
                   10578:   int stepsize;
1.218     brouard  10579:   /* int agelim; */
                   10580:        int ageminl;
1.217     brouard  10581:   int hstepm;
                   10582:   int nhstepm;
1.238     brouard  10583:   int h, i, i1, j, k, nres;
1.218     brouard  10584:        
1.217     brouard  10585:   double agedeb;
                   10586:   double ***p3mat;
1.218     brouard  10587:        
                   10588:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10589:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10590:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10591:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10592:   }
                   10593:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10594:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10595:   
                   10596:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10597:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10598:   
1.218     brouard  10599:   /* agelim=AGESUP; */
                   10600:   ageminl=30;
                   10601:   hstepm=stepsize*YEARM; /* Every year of age */
                   10602:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10603:   
                   10604:   /* hstepm=1;   aff par mois*/
                   10605:   pstamp(ficrespijb);
1.255     brouard  10606:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10607:   i1= pow(2,cptcoveff);
1.218     brouard  10608:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10609:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10610:   /*   k=k+1;  */
1.238     brouard  10611:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10612:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10613:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10614:        continue;
                   10615:       fprintf(ficrespijb,"\n#****** ");
                   10616:       for(j=1;j<=cptcoveff;j++)
                   10617:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10618:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10619:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10620:       }
                   10621:       fprintf(ficrespijb,"******\n");
1.264     brouard  10622:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10623:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10624:        continue;
                   10625:       }
                   10626:       
                   10627:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10628:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10629:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10630:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10631:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10632:        
                   10633:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10634:        
1.266     brouard  10635:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10636:        /* and memory limitations if stepm is small */
                   10637: 
1.238     brouard  10638:        /* oldm=oldms;savm=savms; */
                   10639:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10640:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10641:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10642:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10643:        for(i=1; i<=nlstate;i++)
                   10644:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10645:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10646:        fprintf(ficrespijb,"\n");
1.238     brouard  10647:        for (h=0; h<=nhstepm; h++){
                   10648:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10649:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10650:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10651:          for(i=1; i<=nlstate;i++)
                   10652:            for(j=1; j<=nlstate+ndeath;j++)
                   10653:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10654:          fprintf(ficrespijb,"\n");
                   10655:        }
                   10656:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10657:        fprintf(ficrespijb,"\n");
                   10658:       } /* end age deb */
                   10659:     } /* end combination */
                   10660:   } /* end nres */
1.218     brouard  10661:   return 0;
                   10662:  } /*  hBijx */
1.217     brouard  10663: 
1.180     brouard  10664: 
1.136     brouard  10665: /***********************************************/
                   10666: /**************** Main Program *****************/
                   10667: /***********************************************/
                   10668: 
                   10669: int main(int argc, char *argv[])
                   10670: {
                   10671: #ifdef GSL
                   10672:   const gsl_multimin_fminimizer_type *T;
                   10673:   size_t iteri = 0, it;
                   10674:   int rval = GSL_CONTINUE;
                   10675:   int status = GSL_SUCCESS;
                   10676:   double ssval;
                   10677: #endif
                   10678:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10679:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10680:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10681:   int jj, ll, li, lj, lk;
1.136     brouard  10682:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10683:   int num_filled;
1.136     brouard  10684:   int itimes;
                   10685:   int NDIM=2;
                   10686:   int vpopbased=0;
1.235     brouard  10687:   int nres=0;
1.258     brouard  10688:   int endishere=0;
1.277     brouard  10689:   int noffset=0;
1.274     brouard  10690:   int ncurrv=0; /* Temporary variable */
                   10691:   
1.164     brouard  10692:   char ca[32], cb[32];
1.136     brouard  10693:   /*  FILE *fichtm; *//* Html File */
                   10694:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10695:   struct stat info;
1.191     brouard  10696:   double agedeb=0.;
1.194     brouard  10697: 
                   10698:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10699:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10700: 
1.165     brouard  10701:   double fret;
1.191     brouard  10702:   double dum=0.; /* Dummy variable */
1.136     brouard  10703:   double ***p3mat;
1.218     brouard  10704:   /* double ***mobaverage; */
1.164     brouard  10705: 
                   10706:   char line[MAXLINE];
1.197     brouard  10707:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10708: 
1.234     brouard  10709:   char  modeltemp[MAXLINE];
1.230     brouard  10710:   char resultline[MAXLINE];
                   10711:   
1.136     brouard  10712:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10713:   char *tok, *val; /* pathtot */
1.136     brouard  10714:   int firstobs=1, lastobs=10;
1.195     brouard  10715:   int c,  h , cpt, c2;
1.191     brouard  10716:   int jl=0;
                   10717:   int i1, j1, jk, stepsize=0;
1.194     brouard  10718:   int count=0;
                   10719: 
1.164     brouard  10720:   int *tab; 
1.136     brouard  10721:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10722:   int backcast=0;
1.136     brouard  10723:   int mobilav=0,popforecast=0;
1.191     brouard  10724:   int hstepm=0, nhstepm=0;
1.136     brouard  10725:   int agemortsup;
                   10726:   float  sumlpop=0.;
                   10727:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10728:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10729: 
1.191     brouard  10730:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10731:   double ftolpl=FTOL;
                   10732:   double **prlim;
1.217     brouard  10733:   double **bprlim;
1.136     brouard  10734:   double ***param; /* Matrix of parameters */
1.251     brouard  10735:   double ***paramstart; /* Matrix of starting parameter values */
                   10736:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10737:   double **matcov; /* Matrix of covariance */
1.203     brouard  10738:   double **hess; /* Hessian matrix */
1.136     brouard  10739:   double ***delti3; /* Scale */
                   10740:   double *delti; /* Scale */
                   10741:   double ***eij, ***vareij;
                   10742:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10743: 
1.136     brouard  10744:   double *epj, vepp;
1.164     brouard  10745: 
1.273     brouard  10746:   double dateprev1, dateprev2;
                   10747:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10748:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10749: 
1.136     brouard  10750:   double **ximort;
1.145     brouard  10751:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10752:   int *dcwave;
                   10753: 
1.164     brouard  10754:   char z[1]="c";
1.136     brouard  10755: 
                   10756:   /*char  *strt;*/
                   10757:   char strtend[80];
1.126     brouard  10758: 
1.164     brouard  10759: 
1.126     brouard  10760: /*   setlocale (LC_ALL, ""); */
                   10761: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10762: /*   textdomain (PACKAGE); */
                   10763: /*   setlocale (LC_CTYPE, ""); */
                   10764: /*   setlocale (LC_MESSAGES, ""); */
                   10765: 
                   10766:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10767:   rstart_time = time(NULL);  
                   10768:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10769:   start_time = *localtime(&rstart_time);
1.126     brouard  10770:   curr_time=start_time;
1.157     brouard  10771:   /*tml = *localtime(&start_time.tm_sec);*/
                   10772:   /* strcpy(strstart,asctime(&tml)); */
                   10773:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10774: 
                   10775: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10776: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10777: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10778: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10779: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10780: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10781: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10782: /*   strt=asctime(&tmg); */
                   10783: /*   printf("Time(after) =%s",strstart);  */
                   10784: /*  (void) time (&time_value);
                   10785: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10786: *  tm = *localtime(&time_value);
                   10787: *  strstart=asctime(&tm);
                   10788: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10789: */
                   10790: 
                   10791:   nberr=0; /* Number of errors and warnings */
                   10792:   nbwarn=0;
1.184     brouard  10793: #ifdef WIN32
                   10794:   _getcwd(pathcd, size);
                   10795: #else
1.126     brouard  10796:   getcwd(pathcd, size);
1.184     brouard  10797: #endif
1.191     brouard  10798:   syscompilerinfo(0);
1.196     brouard  10799:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10800:   if(argc <=1){
                   10801:     printf("\nEnter the parameter file name: ");
1.205     brouard  10802:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10803:       printf("ERROR Empty parameter file name\n");
                   10804:       goto end;
                   10805:     }
1.126     brouard  10806:     i=strlen(pathr);
                   10807:     if(pathr[i-1]=='\n')
                   10808:       pathr[i-1]='\0';
1.156     brouard  10809:     i=strlen(pathr);
1.205     brouard  10810:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10811:       pathr[i-1]='\0';
1.205     brouard  10812:     }
                   10813:     i=strlen(pathr);
                   10814:     if( i==0 ){
                   10815:       printf("ERROR Empty parameter file name\n");
                   10816:       goto end;
                   10817:     }
                   10818:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10819:       printf("Pathr |%s|\n",pathr);
                   10820:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10821:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10822:       strcpy (pathtot, val);
                   10823:       if(pathr[0] == '\0') break; /* Dirty */
                   10824:     }
                   10825:   }
1.281     brouard  10826:   else if (argc<=2){
                   10827:     strcpy(pathtot,argv[1]);
                   10828:   }
1.126     brouard  10829:   else{
                   10830:     strcpy(pathtot,argv[1]);
1.281     brouard  10831:     strcpy(z,argv[2]);
                   10832:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10833:   }
                   10834:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10835:   /*cygwin_split_path(pathtot,path,optionfile);
                   10836:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10837:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10838: 
                   10839:   /* Split argv[0], imach program to get pathimach */
                   10840:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10841:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10842:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10843:  /*   strcpy(pathimach,argv[0]); */
                   10844:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10845:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10846:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10847: #ifdef WIN32
                   10848:   _chdir(path); /* Can be a relative path */
                   10849:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10850: #else
1.126     brouard  10851:   chdir(path); /* Can be a relative path */
1.184     brouard  10852:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10853: #endif
                   10854:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10855:   strcpy(command,"mkdir ");
                   10856:   strcat(command,optionfilefiname);
                   10857:   if((outcmd=system(command)) != 0){
1.169     brouard  10858:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10859:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10860:     /* fclose(ficlog); */
                   10861: /*     exit(1); */
                   10862:   }
                   10863: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10864: /*     perror("mkdir"); */
                   10865: /*   } */
                   10866: 
                   10867:   /*-------- arguments in the command line --------*/
                   10868: 
1.186     brouard  10869:   /* Main Log file */
1.126     brouard  10870:   strcat(filelog, optionfilefiname);
                   10871:   strcat(filelog,".log");    /* */
                   10872:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10873:     printf("Problem with logfile %s\n",filelog);
                   10874:     goto end;
                   10875:   }
                   10876:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10877:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10878:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10879:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10880:  path=%s \n\
                   10881:  optionfile=%s\n\
                   10882:  optionfilext=%s\n\
1.156     brouard  10883:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10884: 
1.197     brouard  10885:   syscompilerinfo(1);
1.167     brouard  10886: 
1.126     brouard  10887:   printf("Local time (at start):%s",strstart);
                   10888:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10889:   fflush(ficlog);
                   10890: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10891: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10892: 
                   10893:   /* */
                   10894:   strcpy(fileres,"r");
                   10895:   strcat(fileres, optionfilefiname);
1.201     brouard  10896:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10897:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10898:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10899: 
1.186     brouard  10900:   /* Main ---------arguments file --------*/
1.126     brouard  10901: 
                   10902:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10903:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10904:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10905:     fflush(ficlog);
1.149     brouard  10906:     /* goto end; */
                   10907:     exit(70); 
1.126     brouard  10908:   }
                   10909: 
                   10910:   strcpy(filereso,"o");
1.201     brouard  10911:   strcat(filereso,fileresu);
1.126     brouard  10912:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10913:     printf("Problem with Output resultfile: %s\n", filereso);
                   10914:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10915:     fflush(ficlog);
                   10916:     goto end;
                   10917:   }
1.278     brouard  10918:       /*-------- Rewriting parameter file ----------*/
                   10919:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10920:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10921:   strcat(rfileres,".");    /* */
                   10922:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10923:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10924:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10925:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10926:     fflush(ficlog);
                   10927:     goto end;
                   10928:   }
                   10929:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10930: 
1.278     brouard  10931:                                      
1.126     brouard  10932:   /* Reads comments: lines beginning with '#' */
                   10933:   numlinepar=0;
1.277     brouard  10934:   /* Is it a BOM UTF-8 Windows file? */
                   10935:   /* First parameter line */
1.197     brouard  10936:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10937:     noffset=0;
                   10938:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10939:     {
                   10940:       noffset=noffset+3;
                   10941:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10942:     }
                   10943:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10944:     {
                   10945:       noffset=noffset+2;
                   10946:       printf("# File is an UTF16BE BOM file\n");
                   10947:     }
                   10948:     else if( line[0] == 0 && line[1] == 0)
                   10949:     {
                   10950:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   10951:        noffset=noffset+4;
                   10952:        printf("# File is an UTF16BE BOM file\n");
                   10953:       }
                   10954:     } else{
                   10955:       ;/*printf(" Not a BOM file\n");*/
                   10956:     }
                   10957:   
1.197     brouard  10958:     /* If line starts with a # it is a comment */
1.277     brouard  10959:     if (line[noffset] == '#') {
1.197     brouard  10960:       numlinepar++;
                   10961:       fputs(line,stdout);
                   10962:       fputs(line,ficparo);
1.278     brouard  10963:       fputs(line,ficres);
1.197     brouard  10964:       fputs(line,ficlog);
                   10965:       continue;
                   10966:     }else
                   10967:       break;
                   10968:   }
                   10969:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10970:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10971:     if (num_filled != 5) {
                   10972:       printf("Should be 5 parameters\n");
1.283   ! brouard  10973:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  10974:     }
1.126     brouard  10975:     numlinepar++;
1.197     brouard  10976:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283   ! brouard  10977:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
        !          10978:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
        !          10979:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  10980:   }
                   10981:   /* Second parameter line */
                   10982:   while(fgets(line, MAXLINE, ficpar)) {
1.283   ! brouard  10983:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
        !          10984:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  10985:     if (line[0] == '#') {
                   10986:       numlinepar++;
1.283   ! brouard  10987:       printf("%s",line);
        !          10988:       fprintf(ficres,"%s",line);
        !          10989:       fprintf(ficparo,"%s",line);
        !          10990:       fprintf(ficlog,"%s",line);
1.197     brouard  10991:       continue;
                   10992:     }else
                   10993:       break;
                   10994:   }
1.223     brouard  10995:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10996:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10997:     if (num_filled != 11) {
                   10998:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10999:       printf("but line=%s\n",line);
1.283   ! brouard  11000:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
        !          11001:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11002:     }
1.223     brouard  11003:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283   ! brouard  11004:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
        !          11005:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
        !          11006:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11007:   }
1.203     brouard  11008:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11009:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11010:   /* Third parameter line */
                   11011:   while(fgets(line, MAXLINE, ficpar)) {
                   11012:     /* If line starts with a # it is a comment */
                   11013:     if (line[0] == '#') {
                   11014:       numlinepar++;
1.283   ! brouard  11015:       printf("%s",line);
        !          11016:       fprintf(ficres,"%s",line);
        !          11017:       fprintf(ficparo,"%s",line);
        !          11018:       fprintf(ficlog,"%s",line);
1.197     brouard  11019:       continue;
                   11020:     }else
                   11021:       break;
                   11022:   }
1.201     brouard  11023:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11024:     if (num_filled != 1){
                   11025:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11026:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11027:       model[0]='\0';
                   11028:       goto end;
                   11029:     }
                   11030:     else{
                   11031:       if (model[0]=='+'){
                   11032:        for(i=1; i<=strlen(model);i++)
                   11033:          modeltemp[i-1]=model[i];
1.201     brouard  11034:        strcpy(model,modeltemp); 
1.197     brouard  11035:       }
                   11036:     }
1.199     brouard  11037:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11038:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283   ! brouard  11039:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
        !          11040:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
        !          11041:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11042:   }
                   11043:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11044:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11045:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283   ! brouard  11046:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
        !          11047:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11048:   fflush(ficlog);
1.190     brouard  11049:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11050:   if(model[0]=='#'){
1.279     brouard  11051:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11052:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11053:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11054:     if(mle != -1){
1.279     brouard  11055:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11056:       exit(1);
                   11057:     }
                   11058:   }
1.126     brouard  11059:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11060:     ungetc(c,ficpar);
                   11061:     fgets(line, MAXLINE, ficpar);
                   11062:     numlinepar++;
1.195     brouard  11063:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11064:       z[0]=line[1];
                   11065:     }
                   11066:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11067:     fputs(line, stdout);
                   11068:     //puts(line);
1.126     brouard  11069:     fputs(line,ficparo);
                   11070:     fputs(line,ficlog);
                   11071:   }
                   11072:   ungetc(c,ficpar);
                   11073: 
                   11074:    
1.145     brouard  11075:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11076:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11077:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11078:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11079:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11080:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11081:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11082:   */
                   11083:   if (strlen(model)>1) 
1.187     brouard  11084:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11085:   else
1.187     brouard  11086:     ncovmodel=2; /* Constant and age */
1.133     brouard  11087:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11088:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11089:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11090:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11091:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11092:     fflush(stdout);
                   11093:     fclose (ficlog);
                   11094:     goto end;
                   11095:   }
1.126     brouard  11096:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11097:   delti=delti3[1][1];
                   11098:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11099:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11100: /* We could also provide initial parameters values giving by simple logistic regression 
                   11101:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11102:       /* for(i=1;i<nlstate;i++){ */
                   11103:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11104:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11105:       /* } */
1.126     brouard  11106:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11107:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11108:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11109:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11110:     fclose (ficparo);
                   11111:     fclose (ficlog);
                   11112:     goto end;
                   11113:     exit(0);
1.220     brouard  11114:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11115:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11116:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11117:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11118:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11119:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11120:     hess=matrix(1,npar,1,npar);
1.220     brouard  11121:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11122:     /* Read guessed parameters */
1.126     brouard  11123:     /* Reads comments: lines beginning with '#' */
                   11124:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11125:       ungetc(c,ficpar);
                   11126:       fgets(line, MAXLINE, ficpar);
                   11127:       numlinepar++;
1.141     brouard  11128:       fputs(line,stdout);
1.126     brouard  11129:       fputs(line,ficparo);
                   11130:       fputs(line,ficlog);
                   11131:     }
                   11132:     ungetc(c,ficpar);
                   11133:     
                   11134:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11135:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11136:     for(i=1; i <=nlstate; i++){
1.234     brouard  11137:       j=0;
1.126     brouard  11138:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11139:        if(jj==i) continue;
                   11140:        j++;
                   11141:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11142:        if ((i1 != i) || (j1 != jj)){
                   11143:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11144: It might be a problem of design; if ncovcol and the model are correct\n \
                   11145: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11146:          exit(1);
                   11147:        }
                   11148:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11149:        if(mle==1)
                   11150:          printf("%1d%1d",i,jj);
                   11151:        fprintf(ficlog,"%1d%1d",i,jj);
                   11152:        for(k=1; k<=ncovmodel;k++){
                   11153:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11154:          if(mle==1){
                   11155:            printf(" %lf",param[i][j][k]);
                   11156:            fprintf(ficlog," %lf",param[i][j][k]);
                   11157:          }
                   11158:          else
                   11159:            fprintf(ficlog," %lf",param[i][j][k]);
                   11160:          fprintf(ficparo," %lf",param[i][j][k]);
                   11161:        }
                   11162:        fscanf(ficpar,"\n");
                   11163:        numlinepar++;
                   11164:        if(mle==1)
                   11165:          printf("\n");
                   11166:        fprintf(ficlog,"\n");
                   11167:        fprintf(ficparo,"\n");
1.126     brouard  11168:       }
                   11169:     }  
                   11170:     fflush(ficlog);
1.234     brouard  11171:     
1.251     brouard  11172:     /* Reads parameters values */
1.126     brouard  11173:     p=param[1][1];
1.251     brouard  11174:     pstart=paramstart[1][1];
1.126     brouard  11175:     
                   11176:     /* Reads comments: lines beginning with '#' */
                   11177:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11178:       ungetc(c,ficpar);
                   11179:       fgets(line, MAXLINE, ficpar);
                   11180:       numlinepar++;
1.141     brouard  11181:       fputs(line,stdout);
1.126     brouard  11182:       fputs(line,ficparo);
                   11183:       fputs(line,ficlog);
                   11184:     }
                   11185:     ungetc(c,ficpar);
                   11186: 
                   11187:     for(i=1; i <=nlstate; i++){
                   11188:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11189:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11190:        if ( (i1-i) * (j1-j) != 0){
                   11191:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11192:          exit(1);
                   11193:        }
                   11194:        printf("%1d%1d",i,j);
                   11195:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11196:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11197:        for(k=1; k<=ncovmodel;k++){
                   11198:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11199:          printf(" %le",delti3[i][j][k]);
                   11200:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11201:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11202:        }
                   11203:        fscanf(ficpar,"\n");
                   11204:        numlinepar++;
                   11205:        printf("\n");
                   11206:        fprintf(ficparo,"\n");
                   11207:        fprintf(ficlog,"\n");
1.126     brouard  11208:       }
                   11209:     }
                   11210:     fflush(ficlog);
1.234     brouard  11211:     
1.145     brouard  11212:     /* Reads covariance matrix */
1.126     brouard  11213:     delti=delti3[1][1];
1.220     brouard  11214:                
                   11215:                
1.126     brouard  11216:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11217:                
1.126     brouard  11218:     /* Reads comments: lines beginning with '#' */
                   11219:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11220:       ungetc(c,ficpar);
                   11221:       fgets(line, MAXLINE, ficpar);
                   11222:       numlinepar++;
1.141     brouard  11223:       fputs(line,stdout);
1.126     brouard  11224:       fputs(line,ficparo);
                   11225:       fputs(line,ficlog);
                   11226:     }
                   11227:     ungetc(c,ficpar);
1.220     brouard  11228:                
1.126     brouard  11229:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11230:     hess=matrix(1,npar,1,npar);
1.131     brouard  11231:     for(i=1; i <=npar; i++)
                   11232:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11233:                
1.194     brouard  11234:     /* Scans npar lines */
1.126     brouard  11235:     for(i=1; i <=npar; i++){
1.226     brouard  11236:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11237:       if(count != 3){
1.226     brouard  11238:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11239: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11240: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11241:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11242: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11243: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11244:        exit(1);
1.220     brouard  11245:       }else{
1.226     brouard  11246:        if(mle==1)
                   11247:          printf("%1d%1d%d",i1,j1,jk);
                   11248:       }
                   11249:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11250:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11251:       for(j=1; j <=i; j++){
1.226     brouard  11252:        fscanf(ficpar," %le",&matcov[i][j]);
                   11253:        if(mle==1){
                   11254:          printf(" %.5le",matcov[i][j]);
                   11255:        }
                   11256:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11257:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11258:       }
                   11259:       fscanf(ficpar,"\n");
                   11260:       numlinepar++;
                   11261:       if(mle==1)
1.220     brouard  11262:                                printf("\n");
1.126     brouard  11263:       fprintf(ficlog,"\n");
                   11264:       fprintf(ficparo,"\n");
                   11265:     }
1.194     brouard  11266:     /* End of read covariance matrix npar lines */
1.126     brouard  11267:     for(i=1; i <=npar; i++)
                   11268:       for(j=i+1;j<=npar;j++)
1.226     brouard  11269:        matcov[i][j]=matcov[j][i];
1.126     brouard  11270:     
                   11271:     if(mle==1)
                   11272:       printf("\n");
                   11273:     fprintf(ficlog,"\n");
                   11274:     
                   11275:     fflush(ficlog);
                   11276:     
                   11277:   }    /* End of mle != -3 */
1.218     brouard  11278:   
1.186     brouard  11279:   /*  Main data
                   11280:    */
1.126     brouard  11281:   n= lastobs;
                   11282:   num=lvector(1,n);
                   11283:   moisnais=vector(1,n);
                   11284:   annais=vector(1,n);
                   11285:   moisdc=vector(1,n);
                   11286:   andc=vector(1,n);
1.220     brouard  11287:   weight=vector(1,n);
1.126     brouard  11288:   agedc=vector(1,n);
                   11289:   cod=ivector(1,n);
1.220     brouard  11290:   for(i=1;i<=n;i++){
1.234     brouard  11291:     num[i]=0;
                   11292:     moisnais[i]=0;
                   11293:     annais[i]=0;
                   11294:     moisdc[i]=0;
                   11295:     andc[i]=0;
                   11296:     agedc[i]=0;
                   11297:     cod[i]=0;
                   11298:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11299:   }
1.126     brouard  11300:   mint=matrix(1,maxwav,1,n);
                   11301:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11302:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11303:   tab=ivector(1,NCOVMAX);
1.144     brouard  11304:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11305:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11306: 
1.136     brouard  11307:   /* Reads data from file datafile */
                   11308:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11309:     goto end;
                   11310: 
                   11311:   /* Calculation of the number of parameters from char model */
1.234     brouard  11312:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11313:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11314:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11315:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11316:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11317:   */
                   11318:   
                   11319:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11320:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11321:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11322:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11323:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11324:   TvarF=ivector(1,NCOVMAX); /*  */
                   11325:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11326:   TvarV=ivector(1,NCOVMAX); /*  */
                   11327:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11328:   TvarA=ivector(1,NCOVMAX); /*  */
                   11329:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11330:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11331:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11332:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11333:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11334:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11335:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11336:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11337:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11338: 
1.230     brouard  11339:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11340:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11341:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11342:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11343:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11344:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11345:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11346:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11347:   */
                   11348:   /* For model-covariate k tells which data-covariate to use but
                   11349:     because this model-covariate is a construction we invent a new column
                   11350:     ncovcol + k1
                   11351:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11352:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11353:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11354:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11355:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11356:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11357:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11358:   */
1.145     brouard  11359:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11360:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11361:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11362:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11363:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11364:                         4 covariates (3 plus signs)
                   11365:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11366:                      */  
1.230     brouard  11367:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11368:                                * individual dummy, fixed or varying:
                   11369:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11370:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11371:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11372:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11373:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11374:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11375:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11376:                                * individual quantitative, fixed or varying:
                   11377:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11378:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11379:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11380: /* Main decodemodel */
                   11381: 
1.187     brouard  11382: 
1.223     brouard  11383:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11384:     goto end;
                   11385: 
1.137     brouard  11386:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11387:     nbwarn++;
                   11388:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11389:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11390:   }
1.136     brouard  11391:     /*  if(mle==1){*/
1.137     brouard  11392:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11393:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11394:   }
                   11395: 
                   11396:     /*-calculation of age at interview from date of interview and age at death -*/
                   11397:   agev=matrix(1,maxwav,1,imx);
                   11398: 
                   11399:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11400:     goto end;
                   11401: 
1.126     brouard  11402: 
1.136     brouard  11403:   agegomp=(int)agemin;
                   11404:   free_vector(moisnais,1,n);
                   11405:   free_vector(annais,1,n);
1.126     brouard  11406:   /* free_matrix(mint,1,maxwav,1,n);
                   11407:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11408:   /* free_vector(moisdc,1,n); */
                   11409:   /* free_vector(andc,1,n); */
1.145     brouard  11410:   /* */
                   11411:   
1.126     brouard  11412:   wav=ivector(1,imx);
1.214     brouard  11413:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11414:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11415:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11416:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11417:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11418:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11419:    
                   11420:   /* Concatenates waves */
1.214     brouard  11421:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11422:      Death is a valid wave (if date is known).
                   11423:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11424:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11425:      and mw[mi+1][i]. dh depends on stepm.
                   11426:   */
                   11427: 
1.126     brouard  11428:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11429:   /* Concatenates waves */
1.145     brouard  11430:  
1.215     brouard  11431:   free_vector(moisdc,1,n);
                   11432:   free_vector(andc,1,n);
                   11433: 
1.126     brouard  11434:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11435:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11436:   ncodemax[1]=1;
1.145     brouard  11437:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11438:   cptcoveff=0;
1.220     brouard  11439:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11440:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11441:   }
                   11442:   
                   11443:   ncovcombmax=pow(2,cptcoveff);
                   11444:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11445:   for(i=1;i<ncovcombmax;i++)
                   11446:     invalidvarcomb[i]=0;
                   11447:   
1.211     brouard  11448:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11449:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11450:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11451:   
1.200     brouard  11452:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11453:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11454:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11455:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11456:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11457:    * (currently 0 or 1) in the data.
                   11458:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11459:    * corresponding modality (h,j).
                   11460:    */
                   11461: 
1.145     brouard  11462:   h=0;
                   11463:   /*if (cptcovn > 0) */
1.126     brouard  11464:   m=pow(2,cptcoveff);
                   11465:  
1.144     brouard  11466:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11467:           * For k=4 covariates, h goes from 1 to m=2**k
                   11468:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11469:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11470:           *     h\k   1     2     3     4
1.143     brouard  11471:           *______________________________  
                   11472:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11473:           *     2     2     1     1     1
                   11474:           *     3 i=2 1     2     1     1
                   11475:           *     4     2     2     1     1
                   11476:           *     5 i=3 1 i=2 1     2     1
                   11477:           *     6     2     1     2     1
                   11478:           *     7 i=4 1     2     2     1
                   11479:           *     8     2     2     2     1
1.197     brouard  11480:           *     9 i=5 1 i=3 1 i=2 1     2
                   11481:           *    10     2     1     1     2
                   11482:           *    11 i=6 1     2     1     2
                   11483:           *    12     2     2     1     2
                   11484:           *    13 i=7 1 i=4 1     2     2    
                   11485:           *    14     2     1     2     2
                   11486:           *    15 i=8 1     2     2     2
                   11487:           *    16     2     2     2     2
1.143     brouard  11488:           */
1.212     brouard  11489:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11490:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11491:      * and the value of each covariate?
                   11492:      * V1=1, V2=1, V3=2, V4=1 ?
                   11493:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11494:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11495:      * In order to get the real value in the data, we use nbcode
                   11496:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11497:      * We are keeping this crazy system in order to be able (in the future?) 
                   11498:      * to have more than 2 values (0 or 1) for a covariate.
                   11499:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11500:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11501:      *              bbbbbbbb
                   11502:      *              76543210     
                   11503:      *   h-1        00000101 (6-1=5)
1.219     brouard  11504:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11505:      *           &
                   11506:      *     1        00000001 (1)
1.219     brouard  11507:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11508:      *          +1= 00000001 =1 
1.211     brouard  11509:      *
                   11510:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11511:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11512:      *    >>k'            11
                   11513:      *          &   00000001
                   11514:      *            = 00000001
                   11515:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11516:      * Reverse h=6 and m=16?
                   11517:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11518:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11519:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11520:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11521:      * V3=decodtabm(14,3,2**4)=2
                   11522:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11523:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11524:      *          &1 000000001
                   11525:      *           = 000000001
                   11526:      *         +1= 000000010 =2
                   11527:      *                  2211
                   11528:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11529:      *                  V3=2
1.220     brouard  11530:                 * codtabm and decodtabm are identical
1.211     brouard  11531:      */
                   11532: 
1.145     brouard  11533: 
                   11534:  free_ivector(Ndum,-1,NCOVMAX);
                   11535: 
                   11536: 
1.126     brouard  11537:     
1.186     brouard  11538:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11539:   strcpy(optionfilegnuplot,optionfilefiname);
                   11540:   if(mle==-3)
1.201     brouard  11541:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11542:   strcat(optionfilegnuplot,".gp");
                   11543: 
                   11544:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11545:     printf("Problem with file %s",optionfilegnuplot);
                   11546:   }
                   11547:   else{
1.204     brouard  11548:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11549:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11550:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11551:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11552:   }
                   11553:   /*  fclose(ficgp);*/
1.186     brouard  11554: 
                   11555: 
                   11556:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11557: 
                   11558:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11559:   if(mle==-3)
1.201     brouard  11560:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11561:   strcat(optionfilehtm,".htm");
                   11562:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11563:     printf("Problem with %s \n",optionfilehtm);
                   11564:     exit(0);
1.126     brouard  11565:   }
                   11566: 
                   11567:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11568:   strcat(optionfilehtmcov,"-cov.htm");
                   11569:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11570:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11571:   }
                   11572:   else{
                   11573:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11574: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11575: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11576:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11577:   }
                   11578: 
1.213     brouard  11579:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11580: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11581: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11582: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11583: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11584: \n\
                   11585: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11586:  <ul><li><h4>Parameter files</h4>\n\
                   11587:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11588:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11589:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11590:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11591:  - Date and time at start: %s</ul>\n",\
                   11592:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11593:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11594:          fileres,fileres,\
                   11595:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11596:   fflush(fichtm);
                   11597: 
                   11598:   strcpy(pathr,path);
                   11599:   strcat(pathr,optionfilefiname);
1.184     brouard  11600: #ifdef WIN32
                   11601:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11602: #else
1.126     brouard  11603:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11604: #endif
                   11605:          
1.126     brouard  11606:   
1.220     brouard  11607:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11608:                 and for any valid combination of covariates
1.126     brouard  11609:      and prints on file fileres'p'. */
1.251     brouard  11610:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11611:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11612: 
                   11613:   fprintf(fichtm,"\n");
1.274     brouard  11614:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%f \n<li>Interval for the elementary matrix (in month): stepm=%d",\
                   11615:          ftol, stepm);
                   11616:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11617:   ncurrv=1;
                   11618:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11619:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11620:   ncurrv=i;
                   11621:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11622:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11623:   ncurrv=i;
                   11624:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11625:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11626:   ncurrv=i;
                   11627:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11628:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11629:           nlstate, ndeath, maxwav, mle, weightopt);
                   11630: 
                   11631:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11632: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11633: 
                   11634:   
                   11635:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11636: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11637: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11638:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11639:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11640:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11641:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11642:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11643:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11644: 
1.126     brouard  11645:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11646:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11647:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11648: 
                   11649:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11650:   /* For mortality only */
1.126     brouard  11651:   if (mle==-3){
1.136     brouard  11652:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11653:     for(i=1;i<=NDIM;i++)
                   11654:       for(j=1;j<=NDIM;j++)
                   11655:        ximort[i][j]=0.;
1.186     brouard  11656:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11657:     cens=ivector(1,n);
                   11658:     ageexmed=vector(1,n);
                   11659:     agecens=vector(1,n);
                   11660:     dcwave=ivector(1,n);
1.223     brouard  11661:                
1.126     brouard  11662:     for (i=1; i<=imx; i++){
                   11663:       dcwave[i]=-1;
                   11664:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11665:        if (s[m][i]>nlstate) {
                   11666:          dcwave[i]=m;
                   11667:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11668:          break;
                   11669:        }
1.126     brouard  11670:     }
1.226     brouard  11671:     
1.126     brouard  11672:     for (i=1; i<=imx; i++) {
                   11673:       if (wav[i]>0){
1.226     brouard  11674:        ageexmed[i]=agev[mw[1][i]][i];
                   11675:        j=wav[i];
                   11676:        agecens[i]=1.; 
                   11677:        
                   11678:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11679:          agecens[i]=agev[mw[j][i]][i];
                   11680:          cens[i]= 1;
                   11681:        }else if (ageexmed[i]< 1) 
                   11682:          cens[i]= -1;
                   11683:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11684:          cens[i]=0 ;
1.126     brouard  11685:       }
                   11686:       else cens[i]=-1;
                   11687:     }
                   11688:     
                   11689:     for (i=1;i<=NDIM;i++) {
                   11690:       for (j=1;j<=NDIM;j++)
1.226     brouard  11691:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11692:     }
                   11693:     
1.145     brouard  11694:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11695:     /*printf("%lf %lf", p[1], p[2]);*/
                   11696:     
                   11697:     
1.136     brouard  11698: #ifdef GSL
                   11699:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11700: #else
1.126     brouard  11701:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11702: #endif
1.201     brouard  11703:     strcpy(filerespow,"POW-MORT_"); 
                   11704:     strcat(filerespow,fileresu);
1.126     brouard  11705:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11706:       printf("Problem with resultfile: %s\n", filerespow);
                   11707:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11708:     }
1.136     brouard  11709: #ifdef GSL
                   11710:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11711: #else
1.126     brouard  11712:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11713: #endif
1.126     brouard  11714:     /*  for (i=1;i<=nlstate;i++)
                   11715:        for(j=1;j<=nlstate+ndeath;j++)
                   11716:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11717:     */
                   11718:     fprintf(ficrespow,"\n");
1.136     brouard  11719: #ifdef GSL
                   11720:     /* gsl starts here */ 
                   11721:     T = gsl_multimin_fminimizer_nmsimplex;
                   11722:     gsl_multimin_fminimizer *sfm = NULL;
                   11723:     gsl_vector *ss, *x;
                   11724:     gsl_multimin_function minex_func;
                   11725: 
                   11726:     /* Initial vertex size vector */
                   11727:     ss = gsl_vector_alloc (NDIM);
                   11728:     
                   11729:     if (ss == NULL){
                   11730:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11731:     }
                   11732:     /* Set all step sizes to 1 */
                   11733:     gsl_vector_set_all (ss, 0.001);
                   11734: 
                   11735:     /* Starting point */
1.126     brouard  11736:     
1.136     brouard  11737:     x = gsl_vector_alloc (NDIM);
                   11738:     
                   11739:     if (x == NULL){
                   11740:       gsl_vector_free(ss);
                   11741:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11742:     }
                   11743:   
                   11744:     /* Initialize method and iterate */
                   11745:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11746:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11747:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11748:     gsl_vector_set(x, 0, p[1]);
                   11749:     gsl_vector_set(x, 1, p[2]);
                   11750: 
                   11751:     minex_func.f = &gompertz_f;
                   11752:     minex_func.n = NDIM;
                   11753:     minex_func.params = (void *)&p; /* ??? */
                   11754:     
                   11755:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11756:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11757:     
                   11758:     printf("Iterations beginning .....\n\n");
                   11759:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11760: 
                   11761:     iteri=0;
                   11762:     while (rval == GSL_CONTINUE){
                   11763:       iteri++;
                   11764:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11765:       
                   11766:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11767:       fflush(0);
                   11768:       
                   11769:       if (status) 
                   11770:         break;
                   11771:       
                   11772:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11773:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11774:       
                   11775:       if (rval == GSL_SUCCESS)
                   11776:         printf ("converged to a local maximum at\n");
                   11777:       
                   11778:       printf("%5d ", iteri);
                   11779:       for (it = 0; it < NDIM; it++){
                   11780:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11781:       }
                   11782:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11783:     }
                   11784:     
                   11785:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11786:     
                   11787:     gsl_vector_free(x); /* initial values */
                   11788:     gsl_vector_free(ss); /* inital step size */
                   11789:     for (it=0; it<NDIM; it++){
                   11790:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11791:       fprintf(ficrespow," %.12lf", p[it]);
                   11792:     }
                   11793:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11794: #endif
                   11795: #ifdef POWELL
                   11796:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11797: #endif  
1.126     brouard  11798:     fclose(ficrespow);
                   11799:     
1.203     brouard  11800:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11801: 
                   11802:     for(i=1; i <=NDIM; i++)
                   11803:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11804:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11805:     
                   11806:     printf("\nCovariance matrix\n ");
1.203     brouard  11807:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11808:     for(i=1; i <=NDIM; i++) {
                   11809:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11810:                                printf("%f ",matcov[i][j]);
                   11811:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11812:       }
1.203     brouard  11813:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11814:     }
                   11815:     
                   11816:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11817:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11818:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11819:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11820:     }
1.126     brouard  11821:     lsurv=vector(1,AGESUP);
                   11822:     lpop=vector(1,AGESUP);
                   11823:     tpop=vector(1,AGESUP);
                   11824:     lsurv[agegomp]=100000;
                   11825:     
                   11826:     for (k=agegomp;k<=AGESUP;k++) {
                   11827:       agemortsup=k;
                   11828:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11829:     }
                   11830:     
                   11831:     for (k=agegomp;k<agemortsup;k++)
                   11832:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11833:     
                   11834:     for (k=agegomp;k<agemortsup;k++){
                   11835:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11836:       sumlpop=sumlpop+lpop[k];
                   11837:     }
                   11838:     
                   11839:     tpop[agegomp]=sumlpop;
                   11840:     for (k=agegomp;k<(agemortsup-3);k++){
                   11841:       /*  tpop[k+1]=2;*/
                   11842:       tpop[k+1]=tpop[k]-lpop[k];
                   11843:     }
                   11844:     
                   11845:     
                   11846:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11847:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11848:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11849:     
                   11850:     
                   11851:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11852:                ageminpar=50;
                   11853:                agemaxpar=100;
1.194     brouard  11854:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11855:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11856: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11857: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11858:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11859: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11860: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11861:     }else{
                   11862:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11863:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11864:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11865:                }
1.201     brouard  11866:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11867:                     stepm, weightopt,\
                   11868:                     model,imx,p,matcov,agemortsup);
                   11869:     
                   11870:     free_vector(lsurv,1,AGESUP);
                   11871:     free_vector(lpop,1,AGESUP);
                   11872:     free_vector(tpop,1,AGESUP);
1.220     brouard  11873:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11874:     free_ivector(cens,1,n);
                   11875:     free_vector(agecens,1,n);
                   11876:     free_ivector(dcwave,1,n);
1.220     brouard  11877: #ifdef GSL
1.136     brouard  11878: #endif
1.186     brouard  11879:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11880:   /* Standard  */
                   11881:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11882:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11883:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11884:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11885:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11886:     for (k=1; k<=npar;k++)
                   11887:       printf(" %d %8.5f",k,p[k]);
                   11888:     printf("\n");
1.205     brouard  11889:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11890:       /* mlikeli uses func not funcone */
1.247     brouard  11891:       /* for(i=1;i<nlstate;i++){ */
                   11892:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11893:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11894:       /* } */
1.205     brouard  11895:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11896:     }
                   11897:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11898:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11899:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11900:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11901:     }
                   11902:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11903:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11904:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11905:     for (k=1; k<=npar;k++)
                   11906:       printf(" %d %8.5f",k,p[k]);
                   11907:     printf("\n");
                   11908:     
                   11909:     /*--------- results files --------------*/
1.283   ! brouard  11910:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11911:     
                   11912:     
                   11913:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11914:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11915:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11916:     for(i=1,jk=1; i <=nlstate; i++){
                   11917:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11918:        if (k != i) {
                   11919:          printf("%d%d ",i,k);
                   11920:          fprintf(ficlog,"%d%d ",i,k);
                   11921:          fprintf(ficres,"%1d%1d ",i,k);
                   11922:          for(j=1; j <=ncovmodel; j++){
                   11923:            printf("%12.7f ",p[jk]);
                   11924:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11925:            fprintf(ficres,"%12.7f ",p[jk]);
                   11926:            jk++; 
                   11927:          }
                   11928:          printf("\n");
                   11929:          fprintf(ficlog,"\n");
                   11930:          fprintf(ficres,"\n");
                   11931:        }
1.126     brouard  11932:       }
                   11933:     }
1.203     brouard  11934:     if(mle != 0){
                   11935:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11936:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11937:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11938:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11939:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11940:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11941:        for(k=1; k <=(nlstate+ndeath); k++){
                   11942:          if (k != i) {
                   11943:            printf("%d%d ",i,k);
                   11944:            fprintf(ficlog,"%d%d ",i,k);
                   11945:            for(j=1; j <=ncovmodel; j++){
                   11946:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11947:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11948:              jk++; 
                   11949:            }
                   11950:            printf("\n");
                   11951:            fprintf(ficlog,"\n");
                   11952:          }
                   11953:        }
1.193     brouard  11954:       }
1.203     brouard  11955:     } /* end of hesscov and Wald tests */
1.225     brouard  11956:     
1.203     brouard  11957:     /*  */
1.126     brouard  11958:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11959:     printf("# Scales (for hessian or gradient estimation)\n");
                   11960:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11961:     for(i=1,jk=1; i <=nlstate; i++){
                   11962:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11963:        if (j!=i) {
                   11964:          fprintf(ficres,"%1d%1d",i,j);
                   11965:          printf("%1d%1d",i,j);
                   11966:          fprintf(ficlog,"%1d%1d",i,j);
                   11967:          for(k=1; k<=ncovmodel;k++){
                   11968:            printf(" %.5e",delti[jk]);
                   11969:            fprintf(ficlog," %.5e",delti[jk]);
                   11970:            fprintf(ficres," %.5e",delti[jk]);
                   11971:            jk++;
                   11972:          }
                   11973:          printf("\n");
                   11974:          fprintf(ficlog,"\n");
                   11975:          fprintf(ficres,"\n");
                   11976:        }
1.126     brouard  11977:       }
                   11978:     }
                   11979:     
                   11980:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11981:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11982:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11983:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11984:     /* # 121 Var(a12)\n\ */
                   11985:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11986:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11987:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11988:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11989:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11990:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11991:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11992:     
                   11993:     
                   11994:     /* Just to have a covariance matrix which will be more understandable
                   11995:        even is we still don't want to manage dictionary of variables
                   11996:     */
                   11997:     for(itimes=1;itimes<=2;itimes++){
                   11998:       jj=0;
                   11999:       for(i=1; i <=nlstate; i++){
1.225     brouard  12000:        for(j=1; j <=nlstate+ndeath; j++){
                   12001:          if(j==i) continue;
                   12002:          for(k=1; k<=ncovmodel;k++){
                   12003:            jj++;
                   12004:            ca[0]= k+'a'-1;ca[1]='\0';
                   12005:            if(itimes==1){
                   12006:              if(mle>=1)
                   12007:                printf("#%1d%1d%d",i,j,k);
                   12008:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12009:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12010:            }else{
                   12011:              if(mle>=1)
                   12012:                printf("%1d%1d%d",i,j,k);
                   12013:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12014:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12015:            }
                   12016:            ll=0;
                   12017:            for(li=1;li <=nlstate; li++){
                   12018:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12019:                if(lj==li) continue;
                   12020:                for(lk=1;lk<=ncovmodel;lk++){
                   12021:                  ll++;
                   12022:                  if(ll<=jj){
                   12023:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12024:                    if(ll<jj){
                   12025:                      if(itimes==1){
                   12026:                        if(mle>=1)
                   12027:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12028:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12029:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12030:                      }else{
                   12031:                        if(mle>=1)
                   12032:                          printf(" %.5e",matcov[jj][ll]); 
                   12033:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12034:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12035:                      }
                   12036:                    }else{
                   12037:                      if(itimes==1){
                   12038:                        if(mle>=1)
                   12039:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12040:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12041:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12042:                      }else{
                   12043:                        if(mle>=1)
                   12044:                          printf(" %.7e",matcov[jj][ll]); 
                   12045:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12046:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12047:                      }
                   12048:                    }
                   12049:                  }
                   12050:                } /* end lk */
                   12051:              } /* end lj */
                   12052:            } /* end li */
                   12053:            if(mle>=1)
                   12054:              printf("\n");
                   12055:            fprintf(ficlog,"\n");
                   12056:            fprintf(ficres,"\n");
                   12057:            numlinepar++;
                   12058:          } /* end k*/
                   12059:        } /*end j */
1.126     brouard  12060:       } /* end i */
                   12061:     } /* end itimes */
                   12062:     
                   12063:     fflush(ficlog);
                   12064:     fflush(ficres);
1.225     brouard  12065:     while(fgets(line, MAXLINE, ficpar)) {
                   12066:       /* If line starts with a # it is a comment */
                   12067:       if (line[0] == '#') {
                   12068:        numlinepar++;
                   12069:        fputs(line,stdout);
                   12070:        fputs(line,ficparo);
                   12071:        fputs(line,ficlog);
                   12072:        continue;
                   12073:       }else
                   12074:        break;
                   12075:     }
                   12076:     
1.209     brouard  12077:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12078:     /*   ungetc(c,ficpar); */
                   12079:     /*   fgets(line, MAXLINE, ficpar); */
                   12080:     /*   fputs(line,stdout); */
                   12081:     /*   fputs(line,ficparo); */
                   12082:     /* } */
                   12083:     /* ungetc(c,ficpar); */
1.126     brouard  12084:     
                   12085:     estepm=0;
1.209     brouard  12086:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12087:       
                   12088:       if (num_filled != 6) {
                   12089:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12090:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12091:        goto end;
                   12092:       }
                   12093:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12094:     }
                   12095:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12096:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12097:     
1.209     brouard  12098:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12099:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12100:     if (fage <= 2) {
                   12101:       bage = ageminpar;
                   12102:       fage = agemaxpar;
                   12103:     }
                   12104:     
                   12105:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12106:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12107:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12108:                
1.186     brouard  12109:     /* Other stuffs, more or less useful */    
1.254     brouard  12110:     while(fgets(line, MAXLINE, ficpar)) {
                   12111:       /* If line starts with a # it is a comment */
                   12112:       if (line[0] == '#') {
                   12113:        numlinepar++;
                   12114:        fputs(line,stdout);
                   12115:        fputs(line,ficparo);
                   12116:        fputs(line,ficlog);
                   12117:        continue;
                   12118:       }else
                   12119:        break;
                   12120:     }
                   12121: 
                   12122:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12123:       
                   12124:       if (num_filled != 7) {
                   12125:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12126:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12127:        goto end;
                   12128:       }
                   12129:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12130:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12131:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12132:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12133:     }
1.254     brouard  12134: 
                   12135:     while(fgets(line, MAXLINE, ficpar)) {
                   12136:       /* If line starts with a # it is a comment */
                   12137:       if (line[0] == '#') {
                   12138:        numlinepar++;
                   12139:        fputs(line,stdout);
                   12140:        fputs(line,ficparo);
                   12141:        fputs(line,ficlog);
                   12142:        continue;
                   12143:       }else
                   12144:        break;
1.126     brouard  12145:     }
                   12146:     
                   12147:     
                   12148:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12149:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12150:     
1.254     brouard  12151:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12152:       if (num_filled != 1) {
                   12153:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12154:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12155:        goto end;
                   12156:       }
                   12157:       printf("pop_based=%d\n",popbased);
                   12158:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12159:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12160:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12161:     }
                   12162:      
1.258     brouard  12163:     /* Results */
                   12164:     nresult=0;
                   12165:     do{
                   12166:       if(!fgets(line, MAXLINE, ficpar)){
                   12167:        endishere=1;
                   12168:        parameterline=14;
                   12169:       }else if (line[0] == '#') {
                   12170:        /* If line starts with a # it is a comment */
1.254     brouard  12171:        numlinepar++;
                   12172:        fputs(line,stdout);
                   12173:        fputs(line,ficparo);
                   12174:        fputs(line,ficlog);
                   12175:        continue;
1.258     brouard  12176:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12177:        parameterline=11;
                   12178:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12179:        parameterline=12;
                   12180:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12181:        parameterline=13;
                   12182:       else{
                   12183:        parameterline=14;
1.254     brouard  12184:       }
1.258     brouard  12185:       switch (parameterline){ 
                   12186:       case 11:
                   12187:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12188:          if (num_filled != 8) {
                   12189:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12190:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12191:            goto end;
                   12192:          }
                   12193:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12194:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12195:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12196:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12197:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12198:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12199:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12200: 
1.258     brouard  12201:        }
1.254     brouard  12202:        break;
1.258     brouard  12203:       case 12:
                   12204:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12205:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12206:          if (num_filled != 8) {
1.262     brouard  12207:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12208:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12209:            goto end;
                   12210:          }
                   12211:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12212:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12213:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12214:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12215:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12216:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12217:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12218:        }
1.230     brouard  12219:        break;
1.258     brouard  12220:       case 13:
                   12221:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12222:          if (num_filled == 0){
                   12223:            resultline[0]='\0';
                   12224:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12225:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12226:            break;
                   12227:          } else if (num_filled != 1){
                   12228:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12229:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12230:          }
                   12231:          nresult++; /* Sum of resultlines */
                   12232:          printf("Result %d: result=%s\n",nresult, resultline);
                   12233:          if(nresult > MAXRESULTLINES){
                   12234:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12235:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12236:            goto end;
                   12237:          }
                   12238:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12239:          fprintf(ficparo,"result: %s\n",resultline);
                   12240:          fprintf(ficres,"result: %s\n",resultline);
                   12241:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12242:          break;
1.258     brouard  12243:        case 14: 
1.259     brouard  12244:          if(ncovmodel >2 && nresult==0 ){
                   12245:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12246:            goto end;
                   12247:          }
1.259     brouard  12248:          break;
1.258     brouard  12249:        default:
                   12250:          nresult=1;
                   12251:          decoderesult(".",nresult ); /* No covariate */
                   12252:        }
                   12253:       } /* End switch parameterline */
                   12254:     }while(endishere==0); /* End do */
1.126     brouard  12255:     
1.230     brouard  12256:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12257:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12258:     
                   12259:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12260:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12261:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12262: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12263: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12264:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12265: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12266: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12267:     }else{
1.270     brouard  12268:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12269:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12270:     }
                   12271:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12272:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12273:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12274:                
1.225     brouard  12275:     /*------------ free_vector  -------------*/
                   12276:     /*  chdir(path); */
1.220     brouard  12277:                
1.215     brouard  12278:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12279:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12280:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12281:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12282:     free_lvector(num,1,n);
                   12283:     free_vector(agedc,1,n);
                   12284:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12285:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12286:     fclose(ficparo);
                   12287:     fclose(ficres);
1.220     brouard  12288:                
                   12289:                
1.186     brouard  12290:     /* Other results (useful)*/
1.220     brouard  12291:                
                   12292:                
1.126     brouard  12293:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12294:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12295:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12296:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12297:     fclose(ficrespl);
                   12298: 
                   12299:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12300:     /*#include "hpijx.h"*/
                   12301:     hPijx(p, bage, fage);
1.145     brouard  12302:     fclose(ficrespij);
1.227     brouard  12303:     
1.220     brouard  12304:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12305:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12306:     k=1;
1.126     brouard  12307:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12308:     
1.269     brouard  12309:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12310:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12311:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12312:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12313:        for(k=1;k<=ncovcombmax;k++)
                   12314:          probs[i][j][k]=0.;
1.269     brouard  12315:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12316:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12317:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12318:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12319:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12320:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12321:          for(k=1;k<=ncovcombmax;k++)
                   12322:            mobaverages[i][j][k]=0.;
1.219     brouard  12323:       mobaverage=mobaverages;
                   12324:       if (mobilav!=0) {
1.235     brouard  12325:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12326:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12327:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12328:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12329:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12330:        }
1.269     brouard  12331:       } else if (mobilavproj !=0) {
1.235     brouard  12332:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12333:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12334:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12335:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12336:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12337:        }
1.269     brouard  12338:       }else{
                   12339:        printf("Internal error moving average\n");
                   12340:        fflush(stdout);
                   12341:        exit(1);
1.219     brouard  12342:       }
                   12343:     }/* end if moving average */
1.227     brouard  12344:     
1.126     brouard  12345:     /*---------- Forecasting ------------------*/
                   12346:     if(prevfcast==1){
                   12347:       /*    if(stepm ==1){*/
1.269     brouard  12348:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12349:     }
1.269     brouard  12350: 
                   12351:     /* Backcasting */
1.217     brouard  12352:     if(backcast==1){
1.219     brouard  12353:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12354:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12355:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12356: 
                   12357:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12358: 
                   12359:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12360: 
1.219     brouard  12361:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12362:       fclose(ficresplb);
                   12363: 
1.222     brouard  12364:       hBijx(p, bage, fage, mobaverage);
                   12365:       fclose(ficrespijb);
1.219     brouard  12366: 
1.269     brouard  12367:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12368:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12369:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12370: 
                   12371:       
1.269     brouard  12372:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12373:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12374:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12375:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12376:     }    /* end  Backcasting */
1.268     brouard  12377:  
1.186     brouard  12378:  
                   12379:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12380: 
1.215     brouard  12381:     free_ivector(wav,1,imx);
                   12382:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12383:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12384:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12385:                
                   12386:                
1.127     brouard  12387:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12388:                
1.201     brouard  12389:     strcpy(filerese,"E_");
                   12390:     strcat(filerese,fileresu);
1.126     brouard  12391:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12392:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12393:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12394:     }
1.208     brouard  12395:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12396:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12397: 
                   12398:     pstamp(ficreseij);
1.219     brouard  12399:                
1.235     brouard  12400:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12401:     if (cptcovn < 1){i1=1;}
                   12402:     
                   12403:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12404:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12405:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12406:        continue;
1.219     brouard  12407:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12408:       printf("\n#****** ");
1.225     brouard  12409:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12410:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12411:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12412:       }
                   12413:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12414:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12415:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12416:       }
                   12417:       fprintf(ficreseij,"******\n");
1.235     brouard  12418:       printf("******\n");
1.219     brouard  12419:       
                   12420:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12421:       oldm=oldms;savm=savms;
1.235     brouard  12422:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12423:       
1.219     brouard  12424:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12425:     }
                   12426:     fclose(ficreseij);
1.208     brouard  12427:     printf("done evsij\n");fflush(stdout);
                   12428:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12429: 
1.218     brouard  12430:                
1.227     brouard  12431:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12432:                
1.201     brouard  12433:     strcpy(filerest,"T_");
                   12434:     strcat(filerest,fileresu);
1.127     brouard  12435:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12436:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12437:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12438:     }
1.208     brouard  12439:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12440:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12441:     strcpy(fileresstde,"STDE_");
                   12442:     strcat(fileresstde,fileresu);
1.126     brouard  12443:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12444:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12445:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12446:     }
1.227     brouard  12447:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12448:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12449: 
1.201     brouard  12450:     strcpy(filerescve,"CVE_");
                   12451:     strcat(filerescve,fileresu);
1.126     brouard  12452:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12453:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12454:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12455:     }
1.227     brouard  12456:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12457:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12458: 
1.201     brouard  12459:     strcpy(fileresv,"V_");
                   12460:     strcat(fileresv,fileresu);
1.126     brouard  12461:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12462:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12463:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12464:     }
1.227     brouard  12465:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12466:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12467: 
1.235     brouard  12468:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12469:     if (cptcovn < 1){i1=1;}
                   12470:     
                   12471:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12472:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12473:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12474:        continue;
1.242     brouard  12475:       printf("\n#****** Result for:");
                   12476:       fprintf(ficrest,"\n#****** Result for:");
                   12477:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12478:       for(j=1;j<=cptcoveff;j++){ 
                   12479:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12480:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12481:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12482:       }
1.235     brouard  12483:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12484:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12485:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12486:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12487:       }        
1.208     brouard  12488:       fprintf(ficrest,"******\n");
1.227     brouard  12489:       fprintf(ficlog,"******\n");
                   12490:       printf("******\n");
1.208     brouard  12491:       
                   12492:       fprintf(ficresstdeij,"\n#****** ");
                   12493:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12494:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12495:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12496:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12497:       }
1.235     brouard  12498:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12499:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12500:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12501:       }        
1.208     brouard  12502:       fprintf(ficresstdeij,"******\n");
                   12503:       fprintf(ficrescveij,"******\n");
                   12504:       
                   12505:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12506:       /* pstamp(ficresvij); */
1.225     brouard  12507:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12508:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12509:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12510:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12511:       }        
1.208     brouard  12512:       fprintf(ficresvij,"******\n");
                   12513:       
                   12514:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12515:       oldm=oldms;savm=savms;
1.235     brouard  12516:       printf(" cvevsij ");
                   12517:       fprintf(ficlog, " cvevsij ");
                   12518:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12519:       printf(" end cvevsij \n ");
                   12520:       fprintf(ficlog, " end cvevsij \n ");
                   12521:       
                   12522:       /*
                   12523:        */
                   12524:       /* goto endfree; */
                   12525:       
                   12526:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12527:       pstamp(ficrest);
                   12528:       
1.269     brouard  12529:       epj=vector(1,nlstate+1);
1.208     brouard  12530:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12531:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12532:        cptcod= 0; /* To be deleted */
                   12533:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12534:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12535:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12536:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12537:        if(vpopbased==1)
                   12538:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12539:        else
                   12540:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12541:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12542:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12543:        fprintf(ficrest,"\n");
                   12544:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12545:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12546:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12547:        for(age=bage; age <=fage ;age++){
1.235     brouard  12548:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12549:          if (vpopbased==1) {
                   12550:            if(mobilav ==0){
                   12551:              for(i=1; i<=nlstate;i++)
                   12552:                prlim[i][i]=probs[(int)age][i][k];
                   12553:            }else{ /* mobilav */ 
                   12554:              for(i=1; i<=nlstate;i++)
                   12555:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12556:            }
                   12557:          }
1.219     brouard  12558:          
1.227     brouard  12559:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12560:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12561:          /* printf(" age %4.0f ",age); */
                   12562:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12563:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12564:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12565:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12566:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12567:            }
                   12568:            epj[nlstate+1] +=epj[j];
                   12569:          }
                   12570:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12571:          
1.227     brouard  12572:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12573:            for(j=1;j <=nlstate;j++)
                   12574:              vepp += vareij[i][j][(int)age];
                   12575:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12576:          for(j=1;j <=nlstate;j++){
                   12577:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12578:          }
                   12579:          fprintf(ficrest,"\n");
                   12580:        }
1.208     brouard  12581:       } /* End vpopbased */
1.269     brouard  12582:       free_vector(epj,1,nlstate+1);
1.208     brouard  12583:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12584:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12585:       printf("done selection\n");fflush(stdout);
                   12586:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12587:       
1.235     brouard  12588:     } /* End k selection */
1.227     brouard  12589: 
                   12590:     printf("done State-specific expectancies\n");fflush(stdout);
                   12591:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12592: 
1.269     brouard  12593:     /* variance-covariance of period prevalence*/
                   12594:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12595: 
1.227     brouard  12596:     
                   12597:     free_vector(weight,1,n);
                   12598:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12599:     free_imatrix(s,1,maxwav+1,1,n);
                   12600:     free_matrix(anint,1,maxwav,1,n); 
                   12601:     free_matrix(mint,1,maxwav,1,n);
                   12602:     free_ivector(cod,1,n);
                   12603:     free_ivector(tab,1,NCOVMAX);
                   12604:     fclose(ficresstdeij);
                   12605:     fclose(ficrescveij);
                   12606:     fclose(ficresvij);
                   12607:     fclose(ficrest);
                   12608:     fclose(ficpar);
                   12609:     
                   12610:     
1.126     brouard  12611:     /*---------- End : free ----------------*/
1.219     brouard  12612:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12613:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12614:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12615:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12616:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12617:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12618:   /* endfree:*/
                   12619:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12620:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12621:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12622:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12623:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12624:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12625:   free_matrix(covar,0,NCOVMAX,1,n);
                   12626:   free_matrix(matcov,1,npar,1,npar);
                   12627:   free_matrix(hess,1,npar,1,npar);
                   12628:   /*free_vector(delti,1,npar);*/
                   12629:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12630:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12631:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12632:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12633:   
                   12634:   free_ivector(ncodemax,1,NCOVMAX);
                   12635:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12636:   free_ivector(Dummy,-1,NCOVMAX);
                   12637:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12638:   free_ivector(DummyV,1,NCOVMAX);
                   12639:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12640:   free_ivector(Typevar,-1,NCOVMAX);
                   12641:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12642:   free_ivector(TvarsQ,1,NCOVMAX);
                   12643:   free_ivector(TvarsQind,1,NCOVMAX);
                   12644:   free_ivector(TvarsD,1,NCOVMAX);
                   12645:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12646:   free_ivector(TvarFD,1,NCOVMAX);
                   12647:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12648:   free_ivector(TvarF,1,NCOVMAX);
                   12649:   free_ivector(TvarFind,1,NCOVMAX);
                   12650:   free_ivector(TvarV,1,NCOVMAX);
                   12651:   free_ivector(TvarVind,1,NCOVMAX);
                   12652:   free_ivector(TvarA,1,NCOVMAX);
                   12653:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12654:   free_ivector(TvarFQ,1,NCOVMAX);
                   12655:   free_ivector(TvarFQind,1,NCOVMAX);
                   12656:   free_ivector(TvarVD,1,NCOVMAX);
                   12657:   free_ivector(TvarVDind,1,NCOVMAX);
                   12658:   free_ivector(TvarVQ,1,NCOVMAX);
                   12659:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12660:   free_ivector(Tvarsel,1,NCOVMAX);
                   12661:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12662:   free_ivector(Tposprod,1,NCOVMAX);
                   12663:   free_ivector(Tprod,1,NCOVMAX);
                   12664:   free_ivector(Tvaraff,1,NCOVMAX);
                   12665:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12666:   free_ivector(Tage,1,NCOVMAX);
                   12667:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12668:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12669:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12670:   
                   12671:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12672:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12673:   fflush(fichtm);
                   12674:   fflush(ficgp);
                   12675:   
1.227     brouard  12676:   
1.126     brouard  12677:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12678:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12679:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12680:   }else{
                   12681:     printf("End of Imach\n");
                   12682:     fprintf(ficlog,"End of Imach\n");
                   12683:   }
                   12684:   printf("See log file on %s\n",filelog);
                   12685:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12686:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12687:   rend_time = time(NULL);  
                   12688:   end_time = *localtime(&rend_time);
                   12689:   /* tml = *localtime(&end_time.tm_sec); */
                   12690:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12691:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12692:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12693:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12694:   
1.157     brouard  12695:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12696:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12697:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12698:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12699: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12700:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12701:   fclose(fichtm);
                   12702:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12703:   fclose(fichtmcov);
                   12704:   fclose(ficgp);
                   12705:   fclose(ficlog);
                   12706:   /*------ End -----------*/
1.227     brouard  12707:   
1.281     brouard  12708: 
                   12709: /* Executes gnuplot */
1.227     brouard  12710:   
                   12711:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12712: #ifdef WIN32
1.227     brouard  12713:   if (_chdir(pathcd) != 0)
                   12714:     printf("Can't move to directory %s!\n",path);
                   12715:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12716: #else
1.227     brouard  12717:     if(chdir(pathcd) != 0)
                   12718:       printf("Can't move to directory %s!\n", path);
                   12719:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12720: #endif 
1.126     brouard  12721:     printf("Current directory %s!\n",pathcd);
                   12722:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12723:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12724: #ifdef _WIN32
1.126     brouard  12725:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12726: #endif
                   12727:   if(!stat(plotcmd,&info)){
1.158     brouard  12728:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12729:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12730:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12731:     }else
                   12732:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12733: #ifdef __unix
1.126     brouard  12734:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12735:     if(!stat(plotcmd,&info)){
1.158     brouard  12736:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12737:     }else
                   12738:       strcpy(pplotcmd,plotcmd);
                   12739: #endif
                   12740:   }else
                   12741:     strcpy(pplotcmd,plotcmd);
                   12742:   
                   12743:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12744:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12745:   
1.126     brouard  12746:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12747:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12748:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12749:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12750:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12751:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12752:   }
1.158     brouard  12753:   printf(" Successful, please wait...");
1.126     brouard  12754:   while (z[0] != 'q') {
                   12755:     /* chdir(path); */
1.154     brouard  12756:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12757:     scanf("%s",z);
                   12758: /*     if (z[0] == 'c') system("./imach"); */
                   12759:     if (z[0] == 'e') {
1.158     brouard  12760: #ifdef __APPLE__
1.152     brouard  12761:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12762: #elif __linux
                   12763:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12764: #else
1.152     brouard  12765:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12766: #endif
                   12767:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12768:       system(pplotcmd);
1.126     brouard  12769:     }
                   12770:     else if (z[0] == 'g') system(plotcmd);
                   12771:     else if (z[0] == 'q') exit(0);
                   12772:   }
1.227     brouard  12773: end:
1.126     brouard  12774:   while (z[0] != 'q') {
1.195     brouard  12775:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12776:     scanf("%s",z);
                   12777:   }
1.283   ! brouard  12778:   printf("End\n");
1.282     brouard  12779:   exit(0);
1.126     brouard  12780: }

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