Annotation of imach/src/imach.c, revision 1.284

1.284   ! brouard     1: /* $Id: imach.c,v 1.283 2018/04/19 14:49:16 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.284   ! brouard     4:   Revision 1.283  2018/04/19 14:49:16  brouard
        !             5:   Summary: Some minor bugs fixed
        !             6: 
1.283     brouard     7:   Revision 1.282  2018/02/27 22:50:02  brouard
                      8:   *** empty log message ***
                      9: 
1.282     brouard    10:   Revision 1.281  2018/02/27 19:25:23  brouard
                     11:   Summary: Adding second argument for quitting
                     12: 
1.281     brouard    13:   Revision 1.280  2018/02/21 07:58:13  brouard
                     14:   Summary: 0.99r15
                     15: 
                     16:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     17: 
1.280     brouard    18:   Revision 1.279  2017/07/20 13:35:01  brouard
                     19:   Summary: temporary working
                     20: 
1.279     brouard    21:   Revision 1.278  2017/07/19 14:09:02  brouard
                     22:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     23: 
1.278     brouard    24:   Revision 1.277  2017/07/17 08:53:49  brouard
                     25:   Summary: BOM files can be read now
                     26: 
1.277     brouard    27:   Revision 1.276  2017/06/30 15:48:31  brouard
                     28:   Summary: Graphs improvements
                     29: 
1.276     brouard    30:   Revision 1.275  2017/06/30 13:39:33  brouard
                     31:   Summary: Saito's color
                     32: 
1.275     brouard    33:   Revision 1.274  2017/06/29 09:47:08  brouard
                     34:   Summary: Version 0.99r14
                     35: 
1.274     brouard    36:   Revision 1.273  2017/06/27 11:06:02  brouard
                     37:   Summary: More documentation on projections
                     38: 
1.273     brouard    39:   Revision 1.272  2017/06/27 10:22:40  brouard
                     40:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     41: 
1.272     brouard    42:   Revision 1.271  2017/06/27 10:17:50  brouard
                     43:   Summary: Some bug with rint
                     44: 
1.271     brouard    45:   Revision 1.270  2017/05/24 05:45:29  brouard
                     46:   *** empty log message ***
                     47: 
1.270     brouard    48:   Revision 1.269  2017/05/23 08:39:25  brouard
                     49:   Summary: Code into subroutine, cleanings
                     50: 
1.269     brouard    51:   Revision 1.268  2017/05/18 20:09:32  brouard
                     52:   Summary: backprojection and confidence intervals of backprevalence
                     53: 
1.268     brouard    54:   Revision 1.267  2017/05/13 10:25:05  brouard
                     55:   Summary: temporary save for backprojection
                     56: 
1.267     brouard    57:   Revision 1.266  2017/05/13 07:26:12  brouard
                     58:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     59: 
1.266     brouard    60:   Revision 1.265  2017/04/26 16:22:11  brouard
                     61:   Summary: imach 0.99r13 Some bugs fixed
                     62: 
1.265     brouard    63:   Revision 1.264  2017/04/26 06:01:29  brouard
                     64:   Summary: Labels in graphs
                     65: 
1.264     brouard    66:   Revision 1.263  2017/04/24 15:23:15  brouard
                     67:   Summary: to save
                     68: 
1.263     brouard    69:   Revision 1.262  2017/04/18 16:48:12  brouard
                     70:   *** empty log message ***
                     71: 
1.262     brouard    72:   Revision 1.261  2017/04/05 10:14:09  brouard
                     73:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     74: 
1.261     brouard    75:   Revision 1.260  2017/04/04 17:46:59  brouard
                     76:   Summary: Gnuplot indexations fixed (humm)
                     77: 
1.260     brouard    78:   Revision 1.259  2017/04/04 13:01:16  brouard
                     79:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     80: 
1.259     brouard    81:   Revision 1.258  2017/04/03 10:17:47  brouard
                     82:   Summary: Version 0.99r12
                     83: 
                     84:   Some cleanings, conformed with updated documentation.
                     85: 
1.258     brouard    86:   Revision 1.257  2017/03/29 16:53:30  brouard
                     87:   Summary: Temp
                     88: 
1.257     brouard    89:   Revision 1.256  2017/03/27 05:50:23  brouard
                     90:   Summary: Temporary
                     91: 
1.256     brouard    92:   Revision 1.255  2017/03/08 16:02:28  brouard
                     93:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     94: 
1.255     brouard    95:   Revision 1.254  2017/03/08 07:13:00  brouard
                     96:   Summary: Fixing data parameter line
                     97: 
1.254     brouard    98:   Revision 1.253  2016/12/15 11:59:41  brouard
                     99:   Summary: 0.99 in progress
                    100: 
1.253     brouard   101:   Revision 1.252  2016/09/15 21:15:37  brouard
                    102:   *** empty log message ***
                    103: 
1.252     brouard   104:   Revision 1.251  2016/09/15 15:01:13  brouard
                    105:   Summary: not working
                    106: 
1.251     brouard   107:   Revision 1.250  2016/09/08 16:07:27  brouard
                    108:   Summary: continue
                    109: 
1.250     brouard   110:   Revision 1.249  2016/09/07 17:14:18  brouard
                    111:   Summary: Starting values from frequencies
                    112: 
1.249     brouard   113:   Revision 1.248  2016/09/07 14:10:18  brouard
                    114:   *** empty log message ***
                    115: 
1.248     brouard   116:   Revision 1.247  2016/09/02 11:11:21  brouard
                    117:   *** empty log message ***
                    118: 
1.247     brouard   119:   Revision 1.246  2016/09/02 08:49:22  brouard
                    120:   *** empty log message ***
                    121: 
1.246     brouard   122:   Revision 1.245  2016/09/02 07:25:01  brouard
                    123:   *** empty log message ***
                    124: 
1.245     brouard   125:   Revision 1.244  2016/09/02 07:17:34  brouard
                    126:   *** empty log message ***
                    127: 
1.244     brouard   128:   Revision 1.243  2016/09/02 06:45:35  brouard
                    129:   *** empty log message ***
                    130: 
1.243     brouard   131:   Revision 1.242  2016/08/30 15:01:20  brouard
                    132:   Summary: Fixing a lots
                    133: 
1.242     brouard   134:   Revision 1.241  2016/08/29 17:17:25  brouard
                    135:   Summary: gnuplot problem in Back projection to fix
                    136: 
1.241     brouard   137:   Revision 1.240  2016/08/29 07:53:18  brouard
                    138:   Summary: Better
                    139: 
1.240     brouard   140:   Revision 1.239  2016/08/26 15:51:03  brouard
                    141:   Summary: Improvement in Powell output in order to copy and paste
                    142: 
                    143:   Author:
                    144: 
1.239     brouard   145:   Revision 1.238  2016/08/26 14:23:35  brouard
                    146:   Summary: Starting tests of 0.99
                    147: 
1.238     brouard   148:   Revision 1.237  2016/08/26 09:20:19  brouard
                    149:   Summary: to valgrind
                    150: 
1.237     brouard   151:   Revision 1.236  2016/08/25 10:50:18  brouard
                    152:   *** empty log message ***
                    153: 
1.236     brouard   154:   Revision 1.235  2016/08/25 06:59:23  brouard
                    155:   *** empty log message ***
                    156: 
1.235     brouard   157:   Revision 1.234  2016/08/23 16:51:20  brouard
                    158:   *** empty log message ***
                    159: 
1.234     brouard   160:   Revision 1.233  2016/08/23 07:40:50  brouard
                    161:   Summary: not working
                    162: 
1.233     brouard   163:   Revision 1.232  2016/08/22 14:20:21  brouard
                    164:   Summary: not working
                    165: 
1.232     brouard   166:   Revision 1.231  2016/08/22 07:17:15  brouard
                    167:   Summary: not working
                    168: 
1.231     brouard   169:   Revision 1.230  2016/08/22 06:55:53  brouard
                    170:   Summary: Not working
                    171: 
1.230     brouard   172:   Revision 1.229  2016/07/23 09:45:53  brouard
                    173:   Summary: Completing for func too
                    174: 
1.229     brouard   175:   Revision 1.228  2016/07/22 17:45:30  brouard
                    176:   Summary: Fixing some arrays, still debugging
                    177: 
1.227     brouard   178:   Revision 1.226  2016/07/12 18:42:34  brouard
                    179:   Summary: temp
                    180: 
1.226     brouard   181:   Revision 1.225  2016/07/12 08:40:03  brouard
                    182:   Summary: saving but not running
                    183: 
1.225     brouard   184:   Revision 1.224  2016/07/01 13:16:01  brouard
                    185:   Summary: Fixes
                    186: 
1.224     brouard   187:   Revision 1.223  2016/02/19 09:23:35  brouard
                    188:   Summary: temporary
                    189: 
1.223     brouard   190:   Revision 1.222  2016/02/17 08:14:50  brouard
                    191:   Summary: Probably last 0.98 stable version 0.98r6
                    192: 
1.222     brouard   193:   Revision 1.221  2016/02/15 23:35:36  brouard
                    194:   Summary: minor bug
                    195: 
1.220     brouard   196:   Revision 1.219  2016/02/15 00:48:12  brouard
                    197:   *** empty log message ***
                    198: 
1.219     brouard   199:   Revision 1.218  2016/02/12 11:29:23  brouard
                    200:   Summary: 0.99 Back projections
                    201: 
1.218     brouard   202:   Revision 1.217  2015/12/23 17:18:31  brouard
                    203:   Summary: Experimental backcast
                    204: 
1.217     brouard   205:   Revision 1.216  2015/12/18 17:32:11  brouard
                    206:   Summary: 0.98r4 Warning and status=-2
                    207: 
                    208:   Version 0.98r4 is now:
                    209:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    210:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    211:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    212: 
1.216     brouard   213:   Revision 1.215  2015/12/16 08:52:24  brouard
                    214:   Summary: 0.98r4 working
                    215: 
1.215     brouard   216:   Revision 1.214  2015/12/16 06:57:54  brouard
                    217:   Summary: temporary not working
                    218: 
1.214     brouard   219:   Revision 1.213  2015/12/11 18:22:17  brouard
                    220:   Summary: 0.98r4
                    221: 
1.213     brouard   222:   Revision 1.212  2015/11/21 12:47:24  brouard
                    223:   Summary: minor typo
                    224: 
1.212     brouard   225:   Revision 1.211  2015/11/21 12:41:11  brouard
                    226:   Summary: 0.98r3 with some graph of projected cross-sectional
                    227: 
                    228:   Author: Nicolas Brouard
                    229: 
1.211     brouard   230:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   231:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   232:   Summary: Adding ftolpl parameter
                    233:   Author: N Brouard
                    234: 
                    235:   We had difficulties to get smoothed confidence intervals. It was due
                    236:   to the period prevalence which wasn't computed accurately. The inner
                    237:   parameter ftolpl is now an outer parameter of the .imach parameter
                    238:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    239:   computation are long.
                    240: 
1.209     brouard   241:   Revision 1.208  2015/11/17 14:31:57  brouard
                    242:   Summary: temporary
                    243: 
1.208     brouard   244:   Revision 1.207  2015/10/27 17:36:57  brouard
                    245:   *** empty log message ***
                    246: 
1.207     brouard   247:   Revision 1.206  2015/10/24 07:14:11  brouard
                    248:   *** empty log message ***
                    249: 
1.206     brouard   250:   Revision 1.205  2015/10/23 15:50:53  brouard
                    251:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    252: 
1.205     brouard   253:   Revision 1.204  2015/10/01 16:20:26  brouard
                    254:   Summary: Some new graphs of contribution to likelihood
                    255: 
1.204     brouard   256:   Revision 1.203  2015/09/30 17:45:14  brouard
                    257:   Summary: looking at better estimation of the hessian
                    258: 
                    259:   Also a better criteria for convergence to the period prevalence And
                    260:   therefore adding the number of years needed to converge. (The
                    261:   prevalence in any alive state shold sum to one
                    262: 
1.203     brouard   263:   Revision 1.202  2015/09/22 19:45:16  brouard
                    264:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    265: 
1.202     brouard   266:   Revision 1.201  2015/09/15 17:34:58  brouard
                    267:   Summary: 0.98r0
                    268: 
                    269:   - Some new graphs like suvival functions
                    270:   - Some bugs fixed like model=1+age+V2.
                    271: 
1.201     brouard   272:   Revision 1.200  2015/09/09 16:53:55  brouard
                    273:   Summary: Big bug thanks to Flavia
                    274: 
                    275:   Even model=1+age+V2. did not work anymore
                    276: 
1.200     brouard   277:   Revision 1.199  2015/09/07 14:09:23  brouard
                    278:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    279: 
1.199     brouard   280:   Revision 1.198  2015/09/03 07:14:39  brouard
                    281:   Summary: 0.98q5 Flavia
                    282: 
1.198     brouard   283:   Revision 1.197  2015/09/01 18:24:39  brouard
                    284:   *** empty log message ***
                    285: 
1.197     brouard   286:   Revision 1.196  2015/08/18 23:17:52  brouard
                    287:   Summary: 0.98q5
                    288: 
1.196     brouard   289:   Revision 1.195  2015/08/18 16:28:39  brouard
                    290:   Summary: Adding a hack for testing purpose
                    291: 
                    292:   After reading the title, ftol and model lines, if the comment line has
                    293:   a q, starting with #q, the answer at the end of the run is quit. It
                    294:   permits to run test files in batch with ctest. The former workaround was
                    295:   $ echo q | imach foo.imach
                    296: 
1.195     brouard   297:   Revision 1.194  2015/08/18 13:32:00  brouard
                    298:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    299: 
1.194     brouard   300:   Revision 1.193  2015/08/04 07:17:42  brouard
                    301:   Summary: 0.98q4
                    302: 
1.193     brouard   303:   Revision 1.192  2015/07/16 16:49:02  brouard
                    304:   Summary: Fixing some outputs
                    305: 
1.192     brouard   306:   Revision 1.191  2015/07/14 10:00:33  brouard
                    307:   Summary: Some fixes
                    308: 
1.191     brouard   309:   Revision 1.190  2015/05/05 08:51:13  brouard
                    310:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    311: 
                    312:   Fix 1+age+.
                    313: 
1.190     brouard   314:   Revision 1.189  2015/04/30 14:45:16  brouard
                    315:   Summary: 0.98q2
                    316: 
1.189     brouard   317:   Revision 1.188  2015/04/30 08:27:53  brouard
                    318:   *** empty log message ***
                    319: 
1.188     brouard   320:   Revision 1.187  2015/04/29 09:11:15  brouard
                    321:   *** empty log message ***
                    322: 
1.187     brouard   323:   Revision 1.186  2015/04/23 12:01:52  brouard
                    324:   Summary: V1*age is working now, version 0.98q1
                    325: 
                    326:   Some codes had been disabled in order to simplify and Vn*age was
                    327:   working in the optimization phase, ie, giving correct MLE parameters,
                    328:   but, as usual, outputs were not correct and program core dumped.
                    329: 
1.186     brouard   330:   Revision 1.185  2015/03/11 13:26:42  brouard
                    331:   Summary: Inclusion of compile and links command line for Intel Compiler
                    332: 
1.185     brouard   333:   Revision 1.184  2015/03/11 11:52:39  brouard
                    334:   Summary: Back from Windows 8. Intel Compiler
                    335: 
1.184     brouard   336:   Revision 1.183  2015/03/10 20:34:32  brouard
                    337:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    338: 
                    339:   We use directest instead of original Powell test; probably no
                    340:   incidence on the results, but better justifications;
                    341:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    342:   wrong results.
                    343: 
1.183     brouard   344:   Revision 1.182  2015/02/12 08:19:57  brouard
                    345:   Summary: Trying to keep directest which seems simpler and more general
                    346:   Author: Nicolas Brouard
                    347: 
1.182     brouard   348:   Revision 1.181  2015/02/11 23:22:24  brouard
                    349:   Summary: Comments on Powell added
                    350: 
                    351:   Author:
                    352: 
1.181     brouard   353:   Revision 1.180  2015/02/11 17:33:45  brouard
                    354:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    355: 
1.180     brouard   356:   Revision 1.179  2015/01/04 09:57:06  brouard
                    357:   Summary: back to OS/X
                    358: 
1.179     brouard   359:   Revision 1.178  2015/01/04 09:35:48  brouard
                    360:   *** empty log message ***
                    361: 
1.178     brouard   362:   Revision 1.177  2015/01/03 18:40:56  brouard
                    363:   Summary: Still testing ilc32 on OSX
                    364: 
1.177     brouard   365:   Revision 1.176  2015/01/03 16:45:04  brouard
                    366:   *** empty log message ***
                    367: 
1.176     brouard   368:   Revision 1.175  2015/01/03 16:33:42  brouard
                    369:   *** empty log message ***
                    370: 
1.175     brouard   371:   Revision 1.174  2015/01/03 16:15:49  brouard
                    372:   Summary: Still in cross-compilation
                    373: 
1.174     brouard   374:   Revision 1.173  2015/01/03 12:06:26  brouard
                    375:   Summary: trying to detect cross-compilation
                    376: 
1.173     brouard   377:   Revision 1.172  2014/12/27 12:07:47  brouard
                    378:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    379: 
1.172     brouard   380:   Revision 1.171  2014/12/23 13:26:59  brouard
                    381:   Summary: Back from Visual C
                    382: 
                    383:   Still problem with utsname.h on Windows
                    384: 
1.171     brouard   385:   Revision 1.170  2014/12/23 11:17:12  brouard
                    386:   Summary: Cleaning some \%% back to %%
                    387: 
                    388:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    389: 
1.170     brouard   390:   Revision 1.169  2014/12/22 23:08:31  brouard
                    391:   Summary: 0.98p
                    392: 
                    393:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    394: 
1.169     brouard   395:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   396:   Summary: update
1.169     brouard   397: 
1.168     brouard   398:   Revision 1.167  2014/12/22 13:50:56  brouard
                    399:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    400: 
                    401:   Testing on Linux 64
                    402: 
1.167     brouard   403:   Revision 1.166  2014/12/22 11:40:47  brouard
                    404:   *** empty log message ***
                    405: 
1.166     brouard   406:   Revision 1.165  2014/12/16 11:20:36  brouard
                    407:   Summary: After compiling on Visual C
                    408: 
                    409:   * imach.c (Module): Merging 1.61 to 1.162
                    410: 
1.165     brouard   411:   Revision 1.164  2014/12/16 10:52:11  brouard
                    412:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    413: 
                    414:   * imach.c (Module): Merging 1.61 to 1.162
                    415: 
1.164     brouard   416:   Revision 1.163  2014/12/16 10:30:11  brouard
                    417:   * imach.c (Module): Merging 1.61 to 1.162
                    418: 
1.163     brouard   419:   Revision 1.162  2014/09/25 11:43:39  brouard
                    420:   Summary: temporary backup 0.99!
                    421: 
1.162     brouard   422:   Revision 1.1  2014/09/16 11:06:58  brouard
                    423:   Summary: With some code (wrong) for nlopt
                    424: 
                    425:   Author:
                    426: 
                    427:   Revision 1.161  2014/09/15 20:41:41  brouard
                    428:   Summary: Problem with macro SQR on Intel compiler
                    429: 
1.161     brouard   430:   Revision 1.160  2014/09/02 09:24:05  brouard
                    431:   *** empty log message ***
                    432: 
1.160     brouard   433:   Revision 1.159  2014/09/01 10:34:10  brouard
                    434:   Summary: WIN32
                    435:   Author: Brouard
                    436: 
1.159     brouard   437:   Revision 1.158  2014/08/27 17:11:51  brouard
                    438:   *** empty log message ***
                    439: 
1.158     brouard   440:   Revision 1.157  2014/08/27 16:26:55  brouard
                    441:   Summary: Preparing windows Visual studio version
                    442:   Author: Brouard
                    443: 
                    444:   In order to compile on Visual studio, time.h is now correct and time_t
                    445:   and tm struct should be used. difftime should be used but sometimes I
                    446:   just make the differences in raw time format (time(&now).
                    447:   Trying to suppress #ifdef LINUX
                    448:   Add xdg-open for __linux in order to open default browser.
                    449: 
1.157     brouard   450:   Revision 1.156  2014/08/25 20:10:10  brouard
                    451:   *** empty log message ***
                    452: 
1.156     brouard   453:   Revision 1.155  2014/08/25 18:32:34  brouard
                    454:   Summary: New compile, minor changes
                    455:   Author: Brouard
                    456: 
1.155     brouard   457:   Revision 1.154  2014/06/20 17:32:08  brouard
                    458:   Summary: Outputs now all graphs of convergence to period prevalence
                    459: 
1.154     brouard   460:   Revision 1.153  2014/06/20 16:45:46  brouard
                    461:   Summary: If 3 live state, convergence to period prevalence on same graph
                    462:   Author: Brouard
                    463: 
1.153     brouard   464:   Revision 1.152  2014/06/18 17:54:09  brouard
                    465:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    466: 
1.152     brouard   467:   Revision 1.151  2014/06/18 16:43:30  brouard
                    468:   *** empty log message ***
                    469: 
1.151     brouard   470:   Revision 1.150  2014/06/18 16:42:35  brouard
                    471:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    472:   Author: brouard
                    473: 
1.150     brouard   474:   Revision 1.149  2014/06/18 15:51:14  brouard
                    475:   Summary: Some fixes in parameter files errors
                    476:   Author: Nicolas Brouard
                    477: 
1.149     brouard   478:   Revision 1.148  2014/06/17 17:38:48  brouard
                    479:   Summary: Nothing new
                    480:   Author: Brouard
                    481: 
                    482:   Just a new packaging for OS/X version 0.98nS
                    483: 
1.148     brouard   484:   Revision 1.147  2014/06/16 10:33:11  brouard
                    485:   *** empty log message ***
                    486: 
1.147     brouard   487:   Revision 1.146  2014/06/16 10:20:28  brouard
                    488:   Summary: Merge
                    489:   Author: Brouard
                    490: 
                    491:   Merge, before building revised version.
                    492: 
1.146     brouard   493:   Revision 1.145  2014/06/10 21:23:15  brouard
                    494:   Summary: Debugging with valgrind
                    495:   Author: Nicolas Brouard
                    496: 
                    497:   Lot of changes in order to output the results with some covariates
                    498:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    499:   improve the code.
                    500:   No more memory valgrind error but a lot has to be done in order to
                    501:   continue the work of splitting the code into subroutines.
                    502:   Also, decodemodel has been improved. Tricode is still not
                    503:   optimal. nbcode should be improved. Documentation has been added in
                    504:   the source code.
                    505: 
1.144     brouard   506:   Revision 1.143  2014/01/26 09:45:38  brouard
                    507:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    508: 
                    509:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    510:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    511: 
1.143     brouard   512:   Revision 1.142  2014/01/26 03:57:36  brouard
                    513:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    514: 
                    515:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    516: 
1.142     brouard   517:   Revision 1.141  2014/01/26 02:42:01  brouard
                    518:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    519: 
1.141     brouard   520:   Revision 1.140  2011/09/02 10:37:54  brouard
                    521:   Summary: times.h is ok with mingw32 now.
                    522: 
1.140     brouard   523:   Revision 1.139  2010/06/14 07:50:17  brouard
                    524:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    525:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    526: 
1.139     brouard   527:   Revision 1.138  2010/04/30 18:19:40  brouard
                    528:   *** empty log message ***
                    529: 
1.138     brouard   530:   Revision 1.137  2010/04/29 18:11:38  brouard
                    531:   (Module): Checking covariates for more complex models
                    532:   than V1+V2. A lot of change to be done. Unstable.
                    533: 
1.137     brouard   534:   Revision 1.136  2010/04/26 20:30:53  brouard
                    535:   (Module): merging some libgsl code. Fixing computation
                    536:   of likelione (using inter/intrapolation if mle = 0) in order to
                    537:   get same likelihood as if mle=1.
                    538:   Some cleaning of code and comments added.
                    539: 
1.136     brouard   540:   Revision 1.135  2009/10/29 15:33:14  brouard
                    541:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    542: 
1.135     brouard   543:   Revision 1.134  2009/10/29 13:18:53  brouard
                    544:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    545: 
1.134     brouard   546:   Revision 1.133  2009/07/06 10:21:25  brouard
                    547:   just nforces
                    548: 
1.133     brouard   549:   Revision 1.132  2009/07/06 08:22:05  brouard
                    550:   Many tings
                    551: 
1.132     brouard   552:   Revision 1.131  2009/06/20 16:22:47  brouard
                    553:   Some dimensions resccaled
                    554: 
1.131     brouard   555:   Revision 1.130  2009/05/26 06:44:34  brouard
                    556:   (Module): Max Covariate is now set to 20 instead of 8. A
                    557:   lot of cleaning with variables initialized to 0. Trying to make
                    558:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    559: 
1.130     brouard   560:   Revision 1.129  2007/08/31 13:49:27  lievre
                    561:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    562: 
1.129     lievre    563:   Revision 1.128  2006/06/30 13:02:05  brouard
                    564:   (Module): Clarifications on computing e.j
                    565: 
1.128     brouard   566:   Revision 1.127  2006/04/28 18:11:50  brouard
                    567:   (Module): Yes the sum of survivors was wrong since
                    568:   imach-114 because nhstepm was no more computed in the age
                    569:   loop. Now we define nhstepma in the age loop.
                    570:   (Module): In order to speed up (in case of numerous covariates) we
                    571:   compute health expectancies (without variances) in a first step
                    572:   and then all the health expectancies with variances or standard
                    573:   deviation (needs data from the Hessian matrices) which slows the
                    574:   computation.
                    575:   In the future we should be able to stop the program is only health
                    576:   expectancies and graph are needed without standard deviations.
                    577: 
1.127     brouard   578:   Revision 1.126  2006/04/28 17:23:28  brouard
                    579:   (Module): Yes the sum of survivors was wrong since
                    580:   imach-114 because nhstepm was no more computed in the age
                    581:   loop. Now we define nhstepma in the age loop.
                    582:   Version 0.98h
                    583: 
1.126     brouard   584:   Revision 1.125  2006/04/04 15:20:31  lievre
                    585:   Errors in calculation of health expectancies. Age was not initialized.
                    586:   Forecasting file added.
                    587: 
                    588:   Revision 1.124  2006/03/22 17:13:53  lievre
                    589:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    590:   The log-likelihood is printed in the log file
                    591: 
                    592:   Revision 1.123  2006/03/20 10:52:43  brouard
                    593:   * imach.c (Module): <title> changed, corresponds to .htm file
                    594:   name. <head> headers where missing.
                    595: 
                    596:   * imach.c (Module): Weights can have a decimal point as for
                    597:   English (a comma might work with a correct LC_NUMERIC environment,
                    598:   otherwise the weight is truncated).
                    599:   Modification of warning when the covariates values are not 0 or
                    600:   1.
                    601:   Version 0.98g
                    602: 
                    603:   Revision 1.122  2006/03/20 09:45:41  brouard
                    604:   (Module): Weights can have a decimal point as for
                    605:   English (a comma might work with a correct LC_NUMERIC environment,
                    606:   otherwise the weight is truncated).
                    607:   Modification of warning when the covariates values are not 0 or
                    608:   1.
                    609:   Version 0.98g
                    610: 
                    611:   Revision 1.121  2006/03/16 17:45:01  lievre
                    612:   * imach.c (Module): Comments concerning covariates added
                    613: 
                    614:   * imach.c (Module): refinements in the computation of lli if
                    615:   status=-2 in order to have more reliable computation if stepm is
                    616:   not 1 month. Version 0.98f
                    617: 
                    618:   Revision 1.120  2006/03/16 15:10:38  lievre
                    619:   (Module): refinements in the computation of lli if
                    620:   status=-2 in order to have more reliable computation if stepm is
                    621:   not 1 month. Version 0.98f
                    622: 
                    623:   Revision 1.119  2006/03/15 17:42:26  brouard
                    624:   (Module): Bug if status = -2, the loglikelihood was
                    625:   computed as likelihood omitting the logarithm. Version O.98e
                    626: 
                    627:   Revision 1.118  2006/03/14 18:20:07  brouard
                    628:   (Module): varevsij Comments added explaining the second
                    629:   table of variances if popbased=1 .
                    630:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    631:   (Module): Function pstamp added
                    632:   (Module): Version 0.98d
                    633: 
                    634:   Revision 1.117  2006/03/14 17:16:22  brouard
                    635:   (Module): varevsij Comments added explaining the second
                    636:   table of variances if popbased=1 .
                    637:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    638:   (Module): Function pstamp added
                    639:   (Module): Version 0.98d
                    640: 
                    641:   Revision 1.116  2006/03/06 10:29:27  brouard
                    642:   (Module): Variance-covariance wrong links and
                    643:   varian-covariance of ej. is needed (Saito).
                    644: 
                    645:   Revision 1.115  2006/02/27 12:17:45  brouard
                    646:   (Module): One freematrix added in mlikeli! 0.98c
                    647: 
                    648:   Revision 1.114  2006/02/26 12:57:58  brouard
                    649:   (Module): Some improvements in processing parameter
                    650:   filename with strsep.
                    651: 
                    652:   Revision 1.113  2006/02/24 14:20:24  brouard
                    653:   (Module): Memory leaks checks with valgrind and:
                    654:   datafile was not closed, some imatrix were not freed and on matrix
                    655:   allocation too.
                    656: 
                    657:   Revision 1.112  2006/01/30 09:55:26  brouard
                    658:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    659: 
                    660:   Revision 1.111  2006/01/25 20:38:18  brouard
                    661:   (Module): Lots of cleaning and bugs added (Gompertz)
                    662:   (Module): Comments can be added in data file. Missing date values
                    663:   can be a simple dot '.'.
                    664: 
                    665:   Revision 1.110  2006/01/25 00:51:50  brouard
                    666:   (Module): Lots of cleaning and bugs added (Gompertz)
                    667: 
                    668:   Revision 1.109  2006/01/24 19:37:15  brouard
                    669:   (Module): Comments (lines starting with a #) are allowed in data.
                    670: 
                    671:   Revision 1.108  2006/01/19 18:05:42  lievre
                    672:   Gnuplot problem appeared...
                    673:   To be fixed
                    674: 
                    675:   Revision 1.107  2006/01/19 16:20:37  brouard
                    676:   Test existence of gnuplot in imach path
                    677: 
                    678:   Revision 1.106  2006/01/19 13:24:36  brouard
                    679:   Some cleaning and links added in html output
                    680: 
                    681:   Revision 1.105  2006/01/05 20:23:19  lievre
                    682:   *** empty log message ***
                    683: 
                    684:   Revision 1.104  2005/09/30 16:11:43  lievre
                    685:   (Module): sump fixed, loop imx fixed, and simplifications.
                    686:   (Module): If the status is missing at the last wave but we know
                    687:   that the person is alive, then we can code his/her status as -2
                    688:   (instead of missing=-1 in earlier versions) and his/her
                    689:   contributions to the likelihood is 1 - Prob of dying from last
                    690:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    691:   the healthy state at last known wave). Version is 0.98
                    692: 
                    693:   Revision 1.103  2005/09/30 15:54:49  lievre
                    694:   (Module): sump fixed, loop imx fixed, and simplifications.
                    695: 
                    696:   Revision 1.102  2004/09/15 17:31:30  brouard
                    697:   Add the possibility to read data file including tab characters.
                    698: 
                    699:   Revision 1.101  2004/09/15 10:38:38  brouard
                    700:   Fix on curr_time
                    701: 
                    702:   Revision 1.100  2004/07/12 18:29:06  brouard
                    703:   Add version for Mac OS X. Just define UNIX in Makefile
                    704: 
                    705:   Revision 1.99  2004/06/05 08:57:40  brouard
                    706:   *** empty log message ***
                    707: 
                    708:   Revision 1.98  2004/05/16 15:05:56  brouard
                    709:   New version 0.97 . First attempt to estimate force of mortality
                    710:   directly from the data i.e. without the need of knowing the health
                    711:   state at each age, but using a Gompertz model: log u =a + b*age .
                    712:   This is the basic analysis of mortality and should be done before any
                    713:   other analysis, in order to test if the mortality estimated from the
                    714:   cross-longitudinal survey is different from the mortality estimated
                    715:   from other sources like vital statistic data.
                    716: 
                    717:   The same imach parameter file can be used but the option for mle should be -3.
                    718: 
1.133     brouard   719:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   720:   former routines in order to include the new code within the former code.
                    721: 
                    722:   The output is very simple: only an estimate of the intercept and of
                    723:   the slope with 95% confident intervals.
                    724: 
                    725:   Current limitations:
                    726:   A) Even if you enter covariates, i.e. with the
                    727:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    728:   B) There is no computation of Life Expectancy nor Life Table.
                    729: 
                    730:   Revision 1.97  2004/02/20 13:25:42  lievre
                    731:   Version 0.96d. Population forecasting command line is (temporarily)
                    732:   suppressed.
                    733: 
                    734:   Revision 1.96  2003/07/15 15:38:55  brouard
                    735:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    736:   rewritten within the same printf. Workaround: many printfs.
                    737: 
                    738:   Revision 1.95  2003/07/08 07:54:34  brouard
                    739:   * imach.c (Repository):
                    740:   (Repository): Using imachwizard code to output a more meaningful covariance
                    741:   matrix (cov(a12,c31) instead of numbers.
                    742: 
                    743:   Revision 1.94  2003/06/27 13:00:02  brouard
                    744:   Just cleaning
                    745: 
                    746:   Revision 1.93  2003/06/25 16:33:55  brouard
                    747:   (Module): On windows (cygwin) function asctime_r doesn't
                    748:   exist so I changed back to asctime which exists.
                    749:   (Module): Version 0.96b
                    750: 
                    751:   Revision 1.92  2003/06/25 16:30:45  brouard
                    752:   (Module): On windows (cygwin) function asctime_r doesn't
                    753:   exist so I changed back to asctime which exists.
                    754: 
                    755:   Revision 1.91  2003/06/25 15:30:29  brouard
                    756:   * imach.c (Repository): Duplicated warning errors corrected.
                    757:   (Repository): Elapsed time after each iteration is now output. It
                    758:   helps to forecast when convergence will be reached. Elapsed time
                    759:   is stamped in powell.  We created a new html file for the graphs
                    760:   concerning matrix of covariance. It has extension -cov.htm.
                    761: 
                    762:   Revision 1.90  2003/06/24 12:34:15  brouard
                    763:   (Module): Some bugs corrected for windows. Also, when
                    764:   mle=-1 a template is output in file "or"mypar.txt with the design
                    765:   of the covariance matrix to be input.
                    766: 
                    767:   Revision 1.89  2003/06/24 12:30:52  brouard
                    768:   (Module): Some bugs corrected for windows. Also, when
                    769:   mle=-1 a template is output in file "or"mypar.txt with the design
                    770:   of the covariance matrix to be input.
                    771: 
                    772:   Revision 1.88  2003/06/23 17:54:56  brouard
                    773:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    774: 
                    775:   Revision 1.87  2003/06/18 12:26:01  brouard
                    776:   Version 0.96
                    777: 
                    778:   Revision 1.86  2003/06/17 20:04:08  brouard
                    779:   (Module): Change position of html and gnuplot routines and added
                    780:   routine fileappend.
                    781: 
                    782:   Revision 1.85  2003/06/17 13:12:43  brouard
                    783:   * imach.c (Repository): Check when date of death was earlier that
                    784:   current date of interview. It may happen when the death was just
                    785:   prior to the death. In this case, dh was negative and likelihood
                    786:   was wrong (infinity). We still send an "Error" but patch by
                    787:   assuming that the date of death was just one stepm after the
                    788:   interview.
                    789:   (Repository): Because some people have very long ID (first column)
                    790:   we changed int to long in num[] and we added a new lvector for
                    791:   memory allocation. But we also truncated to 8 characters (left
                    792:   truncation)
                    793:   (Repository): No more line truncation errors.
                    794: 
                    795:   Revision 1.84  2003/06/13 21:44:43  brouard
                    796:   * imach.c (Repository): Replace "freqsummary" at a correct
                    797:   place. It differs from routine "prevalence" which may be called
                    798:   many times. Probs is memory consuming and must be used with
                    799:   parcimony.
                    800:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    801: 
                    802:   Revision 1.83  2003/06/10 13:39:11  lievre
                    803:   *** empty log message ***
                    804: 
                    805:   Revision 1.82  2003/06/05 15:57:20  brouard
                    806:   Add log in  imach.c and  fullversion number is now printed.
                    807: 
                    808: */
                    809: /*
                    810:    Interpolated Markov Chain
                    811: 
                    812:   Short summary of the programme:
                    813:   
1.227     brouard   814:   This program computes Healthy Life Expectancies or State-specific
                    815:   (if states aren't health statuses) Expectancies from
                    816:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    817: 
                    818:   -1- a first survey ("cross") where individuals from different ages
                    819:   are interviewed on their health status or degree of disability (in
                    820:   the case of a health survey which is our main interest)
                    821: 
                    822:   -2- at least a second wave of interviews ("longitudinal") which
                    823:   measure each change (if any) in individual health status.  Health
                    824:   expectancies are computed from the time spent in each health state
                    825:   according to a model. More health states you consider, more time is
                    826:   necessary to reach the Maximum Likelihood of the parameters involved
                    827:   in the model.  The simplest model is the multinomial logistic model
                    828:   where pij is the probability to be observed in state j at the second
                    829:   wave conditional to be observed in state i at the first
                    830:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    831:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    832:   have a more complex model than "constant and age", you should modify
                    833:   the program where the markup *Covariates have to be included here
                    834:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   835:   convergence.
                    836: 
                    837:   The advantage of this computer programme, compared to a simple
                    838:   multinomial logistic model, is clear when the delay between waves is not
                    839:   identical for each individual. Also, if a individual missed an
                    840:   intermediate interview, the information is lost, but taken into
                    841:   account using an interpolation or extrapolation.  
                    842: 
                    843:   hPijx is the probability to be observed in state i at age x+h
                    844:   conditional to the observed state i at age x. The delay 'h' can be
                    845:   split into an exact number (nh*stepm) of unobserved intermediate
                    846:   states. This elementary transition (by month, quarter,
                    847:   semester or year) is modelled as a multinomial logistic.  The hPx
                    848:   matrix is simply the matrix product of nh*stepm elementary matrices
                    849:   and the contribution of each individual to the likelihood is simply
                    850:   hPijx.
                    851: 
                    852:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   853:   of the life expectancies. It also computes the period (stable) prevalence.
                    854: 
                    855: Back prevalence and projections:
1.227     brouard   856: 
                    857:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    858:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    859:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    860:    mobilavproj)
                    861: 
                    862:     Computes the back prevalence limit for any combination of
                    863:     covariate values k at any age between ageminpar and agemaxpar and
                    864:     returns it in **bprlim. In the loops,
                    865: 
                    866:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    867:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    868: 
                    869:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   870:    Computes for any combination of covariates k and any age between bage and fage 
                    871:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    872:                        oldm=oldms;savm=savms;
1.227     brouard   873: 
1.267     brouard   874:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   875:      Computes the transition matrix starting at age 'age' over
                    876:      'nhstepm*hstepm*stepm' months (i.e. until
                    877:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   878:      nhstepm*hstepm matrices. 
                    879: 
                    880:      Returns p3mat[i][j][h] after calling
                    881:      p3mat[i][j][h]=matprod2(newm,
                    882:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    883:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    884:      oldm);
1.226     brouard   885: 
                    886: Important routines
                    887: 
                    888: - func (or funcone), computes logit (pij) distinguishing
                    889:   o fixed variables (single or product dummies or quantitative);
                    890:   o varying variables by:
                    891:    (1) wave (single, product dummies, quantitative), 
                    892:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    893:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    894:        % varying dummy (not done) or quantitative (not done);
                    895: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    896:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    897: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    898:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    899:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   900: 
1.226     brouard   901: 
                    902:   
1.133     brouard   903:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    904:            Institut national d'études démographiques, Paris.
1.126     brouard   905:   This software have been partly granted by Euro-REVES, a concerted action
                    906:   from the European Union.
                    907:   It is copyrighted identically to a GNU software product, ie programme and
                    908:   software can be distributed freely for non commercial use. Latest version
                    909:   can be accessed at http://euroreves.ined.fr/imach .
                    910: 
                    911:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    912:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    913:   
                    914:   **********************************************************************/
                    915: /*
                    916:   main
                    917:   read parameterfile
                    918:   read datafile
                    919:   concatwav
                    920:   freqsummary
                    921:   if (mle >= 1)
                    922:     mlikeli
                    923:   print results files
                    924:   if mle==1 
                    925:      computes hessian
                    926:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    927:       begin-prev-date,...
                    928:   open gnuplot file
                    929:   open html file
1.145     brouard   930:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    931:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    932:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    933:     freexexit2 possible for memory heap.
                    934: 
                    935:   h Pij x                         | pij_nom  ficrestpij
                    936:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    937:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    938:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    939: 
                    940:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    941:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    942:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    943:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    944:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    945: 
1.126     brouard   946:   forecasting if prevfcast==1 prevforecast call prevalence()
                    947:   health expectancies
                    948:   Variance-covariance of DFLE
                    949:   prevalence()
                    950:    movingaverage()
                    951:   varevsij() 
                    952:   if popbased==1 varevsij(,popbased)
                    953:   total life expectancies
                    954:   Variance of period (stable) prevalence
                    955:  end
                    956: */
                    957: 
1.187     brouard   958: /* #define DEBUG */
                    959: /* #define DEBUGBRENT */
1.203     brouard   960: /* #define DEBUGLINMIN */
                    961: /* #define DEBUGHESS */
                    962: #define DEBUGHESSIJ
1.224     brouard   963: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   964: #define POWELL /* Instead of NLOPT */
1.224     brouard   965: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   966: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    967: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   968: 
                    969: #include <math.h>
                    970: #include <stdio.h>
                    971: #include <stdlib.h>
                    972: #include <string.h>
1.226     brouard   973: #include <ctype.h>
1.159     brouard   974: 
                    975: #ifdef _WIN32
                    976: #include <io.h>
1.172     brouard   977: #include <windows.h>
                    978: #include <tchar.h>
1.159     brouard   979: #else
1.126     brouard   980: #include <unistd.h>
1.159     brouard   981: #endif
1.126     brouard   982: 
                    983: #include <limits.h>
                    984: #include <sys/types.h>
1.171     brouard   985: 
                    986: #if defined(__GNUC__)
                    987: #include <sys/utsname.h> /* Doesn't work on Windows */
                    988: #endif
                    989: 
1.126     brouard   990: #include <sys/stat.h>
                    991: #include <errno.h>
1.159     brouard   992: /* extern int errno; */
1.126     brouard   993: 
1.157     brouard   994: /* #ifdef LINUX */
                    995: /* #include <time.h> */
                    996: /* #include "timeval.h" */
                    997: /* #else */
                    998: /* #include <sys/time.h> */
                    999: /* #endif */
                   1000: 
1.126     brouard  1001: #include <time.h>
                   1002: 
1.136     brouard  1003: #ifdef GSL
                   1004: #include <gsl/gsl_errno.h>
                   1005: #include <gsl/gsl_multimin.h>
                   1006: #endif
                   1007: 
1.167     brouard  1008: 
1.162     brouard  1009: #ifdef NLOPT
                   1010: #include <nlopt.h>
                   1011: typedef struct {
                   1012:   double (* function)(double [] );
                   1013: } myfunc_data ;
                   1014: #endif
                   1015: 
1.126     brouard  1016: /* #include <libintl.h> */
                   1017: /* #define _(String) gettext (String) */
                   1018: 
1.251     brouard  1019: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1020: 
                   1021: #define GNUPLOTPROGRAM "gnuplot"
                   1022: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1023: #define FILENAMELENGTH 132
                   1024: 
                   1025: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1026: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1027: 
1.144     brouard  1028: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1029: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1030: 
                   1031: #define NINTERVMAX 8
1.144     brouard  1032: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1033: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1034: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1035: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1036: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1037: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1038: #define MAXN 20000
1.144     brouard  1039: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1040: /* #define AGESUP 130 */
                   1041: #define AGESUP 150
1.268     brouard  1042: #define AGEINF 0
1.218     brouard  1043: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1044: #define AGEBASE 40
1.194     brouard  1045: #define AGEOVERFLOW 1.e20
1.164     brouard  1046: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1047: #ifdef _WIN32
                   1048: #define DIRSEPARATOR '\\'
                   1049: #define CHARSEPARATOR "\\"
                   1050: #define ODIRSEPARATOR '/'
                   1051: #else
1.126     brouard  1052: #define DIRSEPARATOR '/'
                   1053: #define CHARSEPARATOR "/"
                   1054: #define ODIRSEPARATOR '\\'
                   1055: #endif
                   1056: 
1.284   ! brouard  1057: /* $Id: imach.c,v 1.283 2018/04/19 14:49:16 brouard Exp $ */
1.126     brouard  1058: /* $State: Exp $ */
1.196     brouard  1059: #include "version.h"
                   1060: char version[]=__IMACH_VERSION__;
1.283     brouard  1061: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.284   ! brouard  1062: char fullversion[]="$Revision: 1.283 $ $Date: 2018/04/19 14:49:16 $"; 
1.126     brouard  1063: char strstart[80];
                   1064: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1065: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1066: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1067: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1068: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1069: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1070: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1071: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1072: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1073: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1074: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1075: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1076: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1077: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1078: int nsd=0; /**< Total number of single dummy variables (output) */
                   1079: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1080: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1081: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1082: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1083: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1084: int cptcov=0; /* Working variable */
1.218     brouard  1085: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1086: int npar=NPARMAX;
                   1087: int nlstate=2; /* Number of live states */
                   1088: int ndeath=1; /* Number of dead states */
1.130     brouard  1089: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1090: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1091: int popbased=0;
                   1092: 
                   1093: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1094: int maxwav=0; /* Maxim number of waves */
                   1095: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1096: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1097: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1098:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1099: int mle=1, weightopt=0;
1.126     brouard  1100: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1101: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1102: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1103:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1104: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1105: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1106: 
1.130     brouard  1107: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1108: double **matprod2(); /* test */
1.126     brouard  1109: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1110: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1111: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1112: 
1.136     brouard  1113: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1114: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1115: FILE *ficlog, *ficrespow;
1.130     brouard  1116: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1117: double fretone; /* Only one call to likelihood */
1.130     brouard  1118: long ipmx=0; /* Number of contributions */
1.126     brouard  1119: double sw; /* Sum of weights */
                   1120: char filerespow[FILENAMELENGTH];
                   1121: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1122: FILE *ficresilk;
                   1123: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1124: FILE *ficresprobmorprev;
                   1125: FILE *fichtm, *fichtmcov; /* Html File */
                   1126: FILE *ficreseij;
                   1127: char filerese[FILENAMELENGTH];
                   1128: FILE *ficresstdeij;
                   1129: char fileresstde[FILENAMELENGTH];
                   1130: FILE *ficrescveij;
                   1131: char filerescve[FILENAMELENGTH];
                   1132: FILE  *ficresvij;
                   1133: char fileresv[FILENAMELENGTH];
1.269     brouard  1134: 
1.126     brouard  1135: char title[MAXLINE];
1.234     brouard  1136: char model[MAXLINE]; /**< The model line */
1.217     brouard  1137: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1138: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1139: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1140: char command[FILENAMELENGTH];
                   1141: int  outcmd=0;
                   1142: 
1.217     brouard  1143: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1144: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1145: char filelog[FILENAMELENGTH]; /* Log file */
                   1146: char filerest[FILENAMELENGTH];
                   1147: char fileregp[FILENAMELENGTH];
                   1148: char popfile[FILENAMELENGTH];
                   1149: 
                   1150: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1151: 
1.157     brouard  1152: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1153: /* struct timezone tzp; */
                   1154: /* extern int gettimeofday(); */
                   1155: struct tm tml, *gmtime(), *localtime();
                   1156: 
                   1157: extern time_t time();
                   1158: 
                   1159: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1160: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1161: struct tm tm;
                   1162: 
1.126     brouard  1163: char strcurr[80], strfor[80];
                   1164: 
                   1165: char *endptr;
                   1166: long lval;
                   1167: double dval;
                   1168: 
                   1169: #define NR_END 1
                   1170: #define FREE_ARG char*
                   1171: #define FTOL 1.0e-10
                   1172: 
                   1173: #define NRANSI 
1.240     brouard  1174: #define ITMAX 200
                   1175: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1176: 
                   1177: #define TOL 2.0e-4 
                   1178: 
                   1179: #define CGOLD 0.3819660 
                   1180: #define ZEPS 1.0e-10 
                   1181: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1182: 
                   1183: #define GOLD 1.618034 
                   1184: #define GLIMIT 100.0 
                   1185: #define TINY 1.0e-20 
                   1186: 
                   1187: static double maxarg1,maxarg2;
                   1188: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1189: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1190:   
                   1191: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1192: #define rint(a) floor(a+0.5)
1.166     brouard  1193: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1194: #define mytinydouble 1.0e-16
1.166     brouard  1195: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1196: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1197: /* static double dsqrarg; */
                   1198: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1199: static double sqrarg;
                   1200: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1201: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1202: int agegomp= AGEGOMP;
                   1203: 
                   1204: int imx; 
                   1205: int stepm=1;
                   1206: /* Stepm, step in month: minimum step interpolation*/
                   1207: 
                   1208: int estepm;
                   1209: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1210: 
                   1211: int m,nb;
                   1212: long *num;
1.197     brouard  1213: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1214: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1215:                   covariate for which somebody answered excluding 
                   1216:                   undefined. Usually 2: 0 and 1. */
                   1217: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1218:                             covariate for which somebody answered including 
                   1219:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1220: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1221: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1222: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1223: double *ageexmed,*agecens;
                   1224: double dateintmean=0;
                   1225: 
                   1226: double *weight;
                   1227: int **s; /* Status */
1.141     brouard  1228: double *agedc;
1.145     brouard  1229: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1230:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1231:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1232: double **coqvar; /* Fixed quantitative covariate nqv */
                   1233: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1234: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1235: double  idx; 
                   1236: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1237: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1238: /*k          1  2   3   4     5    6    7     8    9 */
                   1239: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1240: /* Tndvar[k]    1   2   3               4          5 */
                   1241: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1242: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1243: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1244: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1245: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1246: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1247: /* Tprod[i]=k           4               7            */
                   1248: /* Tage[i]=k                  5               8      */
                   1249: /* */
                   1250: /* Type                    */
                   1251: /* V         1  2  3  4  5 */
                   1252: /*           F  F  V  V  V */
                   1253: /*           D  Q  D  D  Q */
                   1254: /*                         */
                   1255: int *TvarsD;
                   1256: int *TvarsDind;
                   1257: int *TvarsQ;
                   1258: int *TvarsQind;
                   1259: 
1.235     brouard  1260: #define MAXRESULTLINES 10
                   1261: int nresult=0;
1.258     brouard  1262: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1263: int TKresult[MAXRESULTLINES];
1.237     brouard  1264: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1265: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1266: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1267: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1268: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1269: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1270: 
1.234     brouard  1271: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1272: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1273: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1274: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1275: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1276: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1277: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1278: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1279: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1280: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1281: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1282: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1283: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1284: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1285: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1286: 
1.230     brouard  1287: int *Tvarsel; /**< Selected covariates for output */
                   1288: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1289: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1290: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1291: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1292: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1293: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1294: int *Tage;
1.227     brouard  1295: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1296: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1297: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1298: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1299: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1300: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1301: int **Tvard;
                   1302: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1303: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1304: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1305:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1306:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1307: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1308: double *lsurv, *lpop, *tpop;
                   1309: 
1.231     brouard  1310: #define FD 1; /* Fixed dummy covariate */
                   1311: #define FQ 2; /* Fixed quantitative covariate */
                   1312: #define FP 3; /* Fixed product covariate */
                   1313: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1314: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1315: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1316: #define VD 10; /* Varying dummy covariate */
                   1317: #define VQ 11; /* Varying quantitative covariate */
                   1318: #define VP 12; /* Varying product covariate */
                   1319: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1320: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1321: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1322: #define APFD 16; /* Age product * fixed dummy covariate */
                   1323: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1324: #define APVD 18; /* Age product * varying dummy covariate */
                   1325: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1326: 
                   1327: #define FTYPE 1; /* Fixed covariate */
                   1328: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1329: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1330: 
                   1331: struct kmodel{
                   1332:        int maintype; /* main type */
                   1333:        int subtype; /* subtype */
                   1334: };
                   1335: struct kmodel modell[NCOVMAX];
                   1336: 
1.143     brouard  1337: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1338: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1339: 
                   1340: /**************** split *************************/
                   1341: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1342: {
                   1343:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1344:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1345:   */ 
                   1346:   char *ss;                            /* pointer */
1.186     brouard  1347:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1348: 
                   1349:   l1 = strlen(path );                  /* length of path */
                   1350:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1351:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1352:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1353:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1354:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1355:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1356:     /* get current working directory */
                   1357:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1358: #ifdef WIN32
                   1359:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1360: #else
                   1361:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1362: #endif
1.126     brouard  1363:       return( GLOCK_ERROR_GETCWD );
                   1364:     }
                   1365:     /* got dirc from getcwd*/
                   1366:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1367:   } else {                             /* strip directory from path */
1.126     brouard  1368:     ss++;                              /* after this, the filename */
                   1369:     l2 = strlen( ss );                 /* length of filename */
                   1370:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1371:     strcpy( name, ss );                /* save file name */
                   1372:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1373:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1374:     printf(" DIRC2 = %s \n",dirc);
                   1375:   }
                   1376:   /* We add a separator at the end of dirc if not exists */
                   1377:   l1 = strlen( dirc );                 /* length of directory */
                   1378:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1379:     dirc[l1] =  DIRSEPARATOR;
                   1380:     dirc[l1+1] = 0; 
                   1381:     printf(" DIRC3 = %s \n",dirc);
                   1382:   }
                   1383:   ss = strrchr( name, '.' );           /* find last / */
                   1384:   if (ss >0){
                   1385:     ss++;
                   1386:     strcpy(ext,ss);                    /* save extension */
                   1387:     l1= strlen( name);
                   1388:     l2= strlen(ss)+1;
                   1389:     strncpy( finame, name, l1-l2);
                   1390:     finame[l1-l2]= 0;
                   1391:   }
                   1392: 
                   1393:   return( 0 );                         /* we're done */
                   1394: }
                   1395: 
                   1396: 
                   1397: /******************************************/
                   1398: 
                   1399: void replace_back_to_slash(char *s, char*t)
                   1400: {
                   1401:   int i;
                   1402:   int lg=0;
                   1403:   i=0;
                   1404:   lg=strlen(t);
                   1405:   for(i=0; i<= lg; i++) {
                   1406:     (s[i] = t[i]);
                   1407:     if (t[i]== '\\') s[i]='/';
                   1408:   }
                   1409: }
                   1410: 
1.132     brouard  1411: char *trimbb(char *out, char *in)
1.137     brouard  1412: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1413:   char *s;
                   1414:   s=out;
                   1415:   while (*in != '\0'){
1.137     brouard  1416:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1417:       in++;
                   1418:     }
                   1419:     *out++ = *in++;
                   1420:   }
                   1421:   *out='\0';
                   1422:   return s;
                   1423: }
                   1424: 
1.187     brouard  1425: /* char *substrchaine(char *out, char *in, char *chain) */
                   1426: /* { */
                   1427: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1428: /*   char *s, *t; */
                   1429: /*   t=in;s=out; */
                   1430: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1431: /*     *out++ = *in++; */
                   1432: /*   } */
                   1433: 
                   1434: /*   /\* *in matches *chain *\/ */
                   1435: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1436: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1437: /*   } */
                   1438: /*   in--; chain--; */
                   1439: /*   while ( (*in != '\0')){ */
                   1440: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1441: /*     *out++ = *in++; */
                   1442: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1443: /*   } */
                   1444: /*   *out='\0'; */
                   1445: /*   out=s; */
                   1446: /*   return out; */
                   1447: /* } */
                   1448: char *substrchaine(char *out, char *in, char *chain)
                   1449: {
                   1450:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1451:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1452: 
                   1453:   char *strloc;
                   1454: 
                   1455:   strcpy (out, in); 
                   1456:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1457:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1458:   if(strloc != NULL){ 
                   1459:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1460:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1461:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1462:   }
                   1463:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1464:   return out;
                   1465: }
                   1466: 
                   1467: 
1.145     brouard  1468: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1469: {
1.187     brouard  1470:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1471:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1472:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1473:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1474:   */
1.160     brouard  1475:   char *s, *t;
1.145     brouard  1476:   t=in;s=in;
                   1477:   while ((*in != occ) && (*in != '\0')){
                   1478:     *alocc++ = *in++;
                   1479:   }
                   1480:   if( *in == occ){
                   1481:     *(alocc)='\0';
                   1482:     s=++in;
                   1483:   }
                   1484:  
                   1485:   if (s == t) {/* occ not found */
                   1486:     *(alocc-(in-s))='\0';
                   1487:     in=s;
                   1488:   }
                   1489:   while ( *in != '\0'){
                   1490:     *blocc++ = *in++;
                   1491:   }
                   1492: 
                   1493:   *blocc='\0';
                   1494:   return t;
                   1495: }
1.137     brouard  1496: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1497: {
1.187     brouard  1498:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1499:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1500:      gives blocc="abcdef2ghi" and alocc="j".
                   1501:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1502:   */
                   1503:   char *s, *t;
                   1504:   t=in;s=in;
                   1505:   while (*in != '\0'){
                   1506:     while( *in == occ){
                   1507:       *blocc++ = *in++;
                   1508:       s=in;
                   1509:     }
                   1510:     *blocc++ = *in++;
                   1511:   }
                   1512:   if (s == t) /* occ not found */
                   1513:     *(blocc-(in-s))='\0';
                   1514:   else
                   1515:     *(blocc-(in-s)-1)='\0';
                   1516:   in=s;
                   1517:   while ( *in != '\0'){
                   1518:     *alocc++ = *in++;
                   1519:   }
                   1520: 
                   1521:   *alocc='\0';
                   1522:   return s;
                   1523: }
                   1524: 
1.126     brouard  1525: int nbocc(char *s, char occ)
                   1526: {
                   1527:   int i,j=0;
                   1528:   int lg=20;
                   1529:   i=0;
                   1530:   lg=strlen(s);
                   1531:   for(i=0; i<= lg; i++) {
1.234     brouard  1532:     if  (s[i] == occ ) j++;
1.126     brouard  1533:   }
                   1534:   return j;
                   1535: }
                   1536: 
1.137     brouard  1537: /* void cutv(char *u,char *v, char*t, char occ) */
                   1538: /* { */
                   1539: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1540: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1541: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1542: /*   int i,lg,j,p=0; */
                   1543: /*   i=0; */
                   1544: /*   lg=strlen(t); */
                   1545: /*   for(j=0; j<=lg-1; j++) { */
                   1546: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1547: /*   } */
1.126     brouard  1548: 
1.137     brouard  1549: /*   for(j=0; j<p; j++) { */
                   1550: /*     (u[j] = t[j]); */
                   1551: /*   } */
                   1552: /*      u[p]='\0'; */
1.126     brouard  1553: 
1.137     brouard  1554: /*    for(j=0; j<= lg; j++) { */
                   1555: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1556: /*   } */
                   1557: /* } */
1.126     brouard  1558: 
1.160     brouard  1559: #ifdef _WIN32
                   1560: char * strsep(char **pp, const char *delim)
                   1561: {
                   1562:   char *p, *q;
                   1563:          
                   1564:   if ((p = *pp) == NULL)
                   1565:     return 0;
                   1566:   if ((q = strpbrk (p, delim)) != NULL)
                   1567:   {
                   1568:     *pp = q + 1;
                   1569:     *q = '\0';
                   1570:   }
                   1571:   else
                   1572:     *pp = 0;
                   1573:   return p;
                   1574: }
                   1575: #endif
                   1576: 
1.126     brouard  1577: /********************** nrerror ********************/
                   1578: 
                   1579: void nrerror(char error_text[])
                   1580: {
                   1581:   fprintf(stderr,"ERREUR ...\n");
                   1582:   fprintf(stderr,"%s\n",error_text);
                   1583:   exit(EXIT_FAILURE);
                   1584: }
                   1585: /*********************** vector *******************/
                   1586: double *vector(int nl, int nh)
                   1587: {
                   1588:   double *v;
                   1589:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1590:   if (!v) nrerror("allocation failure in vector");
                   1591:   return v-nl+NR_END;
                   1592: }
                   1593: 
                   1594: /************************ free vector ******************/
                   1595: void free_vector(double*v, int nl, int nh)
                   1596: {
                   1597:   free((FREE_ARG)(v+nl-NR_END));
                   1598: }
                   1599: 
                   1600: /************************ivector *******************************/
                   1601: int *ivector(long nl,long nh)
                   1602: {
                   1603:   int *v;
                   1604:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1605:   if (!v) nrerror("allocation failure in ivector");
                   1606:   return v-nl+NR_END;
                   1607: }
                   1608: 
                   1609: /******************free ivector **************************/
                   1610: void free_ivector(int *v, long nl, long nh)
                   1611: {
                   1612:   free((FREE_ARG)(v+nl-NR_END));
                   1613: }
                   1614: 
                   1615: /************************lvector *******************************/
                   1616: long *lvector(long nl,long nh)
                   1617: {
                   1618:   long *v;
                   1619:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1620:   if (!v) nrerror("allocation failure in ivector");
                   1621:   return v-nl+NR_END;
                   1622: }
                   1623: 
                   1624: /******************free lvector **************************/
                   1625: void free_lvector(long *v, long nl, long nh)
                   1626: {
                   1627:   free((FREE_ARG)(v+nl-NR_END));
                   1628: }
                   1629: 
                   1630: /******************* imatrix *******************************/
                   1631: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1632:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1633: { 
                   1634:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1635:   int **m; 
                   1636:   
                   1637:   /* allocate pointers to rows */ 
                   1638:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1639:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1640:   m += NR_END; 
                   1641:   m -= nrl; 
                   1642:   
                   1643:   
                   1644:   /* allocate rows and set pointers to them */ 
                   1645:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1646:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1647:   m[nrl] += NR_END; 
                   1648:   m[nrl] -= ncl; 
                   1649:   
                   1650:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1651:   
                   1652:   /* return pointer to array of pointers to rows */ 
                   1653:   return m; 
                   1654: } 
                   1655: 
                   1656: /****************** free_imatrix *************************/
                   1657: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1658:       int **m;
                   1659:       long nch,ncl,nrh,nrl; 
                   1660:      /* free an int matrix allocated by imatrix() */ 
                   1661: { 
                   1662:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1663:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1664: } 
                   1665: 
                   1666: /******************* matrix *******************************/
                   1667: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1668: {
                   1669:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1670:   double **m;
                   1671: 
                   1672:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1673:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1674:   m += NR_END;
                   1675:   m -= nrl;
                   1676: 
                   1677:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1678:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1679:   m[nrl] += NR_END;
                   1680:   m[nrl] -= ncl;
                   1681: 
                   1682:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1683:   return m;
1.145     brouard  1684:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1685: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1686: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1687:    */
                   1688: }
                   1689: 
                   1690: /*************************free matrix ************************/
                   1691: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1692: {
                   1693:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1694:   free((FREE_ARG)(m+nrl-NR_END));
                   1695: }
                   1696: 
                   1697: /******************* ma3x *******************************/
                   1698: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1699: {
                   1700:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1701:   double ***m;
                   1702: 
                   1703:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1704:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1705:   m += NR_END;
                   1706:   m -= nrl;
                   1707: 
                   1708:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1709:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1710:   m[nrl] += NR_END;
                   1711:   m[nrl] -= ncl;
                   1712: 
                   1713:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1714: 
                   1715:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1716:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1717:   m[nrl][ncl] += NR_END;
                   1718:   m[nrl][ncl] -= nll;
                   1719:   for (j=ncl+1; j<=nch; j++) 
                   1720:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1721:   
                   1722:   for (i=nrl+1; i<=nrh; i++) {
                   1723:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1724:     for (j=ncl+1; j<=nch; j++) 
                   1725:       m[i][j]=m[i][j-1]+nlay;
                   1726:   }
                   1727:   return m; 
                   1728:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1729:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1730:   */
                   1731: }
                   1732: 
                   1733: /*************************free ma3x ************************/
                   1734: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1735: {
                   1736:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1737:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1738:   free((FREE_ARG)(m+nrl-NR_END));
                   1739: }
                   1740: 
                   1741: /*************** function subdirf ***********/
                   1742: char *subdirf(char fileres[])
                   1743: {
                   1744:   /* Caution optionfilefiname is hidden */
                   1745:   strcpy(tmpout,optionfilefiname);
                   1746:   strcat(tmpout,"/"); /* Add to the right */
                   1747:   strcat(tmpout,fileres);
                   1748:   return tmpout;
                   1749: }
                   1750: 
                   1751: /*************** function subdirf2 ***********/
                   1752: char *subdirf2(char fileres[], char *preop)
                   1753: {
                   1754:   
                   1755:   /* Caution optionfilefiname is hidden */
                   1756:   strcpy(tmpout,optionfilefiname);
                   1757:   strcat(tmpout,"/");
                   1758:   strcat(tmpout,preop);
                   1759:   strcat(tmpout,fileres);
                   1760:   return tmpout;
                   1761: }
                   1762: 
                   1763: /*************** function subdirf3 ***********/
                   1764: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1765: {
                   1766:   
                   1767:   /* Caution optionfilefiname is hidden */
                   1768:   strcpy(tmpout,optionfilefiname);
                   1769:   strcat(tmpout,"/");
                   1770:   strcat(tmpout,preop);
                   1771:   strcat(tmpout,preop2);
                   1772:   strcat(tmpout,fileres);
                   1773:   return tmpout;
                   1774: }
1.213     brouard  1775:  
                   1776: /*************** function subdirfext ***********/
                   1777: char *subdirfext(char fileres[], char *preop, char *postop)
                   1778: {
                   1779:   
                   1780:   strcpy(tmpout,preop);
                   1781:   strcat(tmpout,fileres);
                   1782:   strcat(tmpout,postop);
                   1783:   return tmpout;
                   1784: }
1.126     brouard  1785: 
1.213     brouard  1786: /*************** function subdirfext3 ***********/
                   1787: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1788: {
                   1789:   
                   1790:   /* Caution optionfilefiname is hidden */
                   1791:   strcpy(tmpout,optionfilefiname);
                   1792:   strcat(tmpout,"/");
                   1793:   strcat(tmpout,preop);
                   1794:   strcat(tmpout,fileres);
                   1795:   strcat(tmpout,postop);
                   1796:   return tmpout;
                   1797: }
                   1798:  
1.162     brouard  1799: char *asc_diff_time(long time_sec, char ascdiff[])
                   1800: {
                   1801:   long sec_left, days, hours, minutes;
                   1802:   days = (time_sec) / (60*60*24);
                   1803:   sec_left = (time_sec) % (60*60*24);
                   1804:   hours = (sec_left) / (60*60) ;
                   1805:   sec_left = (sec_left) %(60*60);
                   1806:   minutes = (sec_left) /60;
                   1807:   sec_left = (sec_left) % (60);
                   1808:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1809:   return ascdiff;
                   1810: }
                   1811: 
1.126     brouard  1812: /***************** f1dim *************************/
                   1813: extern int ncom; 
                   1814: extern double *pcom,*xicom;
                   1815: extern double (*nrfunc)(double []); 
                   1816:  
                   1817: double f1dim(double x) 
                   1818: { 
                   1819:   int j; 
                   1820:   double f;
                   1821:   double *xt; 
                   1822:  
                   1823:   xt=vector(1,ncom); 
                   1824:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1825:   f=(*nrfunc)(xt); 
                   1826:   free_vector(xt,1,ncom); 
                   1827:   return f; 
                   1828: } 
                   1829: 
                   1830: /*****************brent *************************/
                   1831: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1832: {
                   1833:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1834:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1835:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1836:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1837:    * returned function value. 
                   1838:   */
1.126     brouard  1839:   int iter; 
                   1840:   double a,b,d,etemp;
1.159     brouard  1841:   double fu=0,fv,fw,fx;
1.164     brouard  1842:   double ftemp=0.;
1.126     brouard  1843:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1844:   double e=0.0; 
                   1845:  
                   1846:   a=(ax < cx ? ax : cx); 
                   1847:   b=(ax > cx ? ax : cx); 
                   1848:   x=w=v=bx; 
                   1849:   fw=fv=fx=(*f)(x); 
                   1850:   for (iter=1;iter<=ITMAX;iter++) { 
                   1851:     xm=0.5*(a+b); 
                   1852:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1853:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1854:     printf(".");fflush(stdout);
                   1855:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1856: #ifdef DEBUGBRENT
1.126     brouard  1857:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1858:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1859:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1860: #endif
                   1861:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1862:       *xmin=x; 
                   1863:       return fx; 
                   1864:     } 
                   1865:     ftemp=fu;
                   1866:     if (fabs(e) > tol1) { 
                   1867:       r=(x-w)*(fx-fv); 
                   1868:       q=(x-v)*(fx-fw); 
                   1869:       p=(x-v)*q-(x-w)*r; 
                   1870:       q=2.0*(q-r); 
                   1871:       if (q > 0.0) p = -p; 
                   1872:       q=fabs(q); 
                   1873:       etemp=e; 
                   1874:       e=d; 
                   1875:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1876:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1877:       else { 
1.224     brouard  1878:                                d=p/q; 
                   1879:                                u=x+d; 
                   1880:                                if (u-a < tol2 || b-u < tol2) 
                   1881:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1882:       } 
                   1883:     } else { 
                   1884:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1885:     } 
                   1886:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1887:     fu=(*f)(u); 
                   1888:     if (fu <= fx) { 
                   1889:       if (u >= x) a=x; else b=x; 
                   1890:       SHFT(v,w,x,u) 
1.183     brouard  1891:       SHFT(fv,fw,fx,fu) 
                   1892:     } else { 
                   1893:       if (u < x) a=u; else b=u; 
                   1894:       if (fu <= fw || w == x) { 
1.224     brouard  1895:                                v=w; 
                   1896:                                w=u; 
                   1897:                                fv=fw; 
                   1898:                                fw=fu; 
1.183     brouard  1899:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1900:                                v=u; 
                   1901:                                fv=fu; 
1.183     brouard  1902:       } 
                   1903:     } 
1.126     brouard  1904:   } 
                   1905:   nrerror("Too many iterations in brent"); 
                   1906:   *xmin=x; 
                   1907:   return fx; 
                   1908: } 
                   1909: 
                   1910: /****************** mnbrak ***********************/
                   1911: 
                   1912: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1913:            double (*func)(double)) 
1.183     brouard  1914: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1915: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1916: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1917: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1918:    */
1.126     brouard  1919:   double ulim,u,r,q, dum;
                   1920:   double fu; 
1.187     brouard  1921: 
                   1922:   double scale=10.;
                   1923:   int iterscale=0;
                   1924: 
                   1925:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1926:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1927: 
                   1928: 
                   1929:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1930:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1931:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1932:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1933:   /* } */
                   1934: 
1.126     brouard  1935:   if (*fb > *fa) { 
                   1936:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1937:     SHFT(dum,*fb,*fa,dum) 
                   1938:   } 
1.126     brouard  1939:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1940:   *fc=(*func)(*cx); 
1.183     brouard  1941: #ifdef DEBUG
1.224     brouard  1942:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1943:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1944: #endif
1.224     brouard  1945:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1946:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1947:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1948:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1949:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1950:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1951:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1952:       fu=(*func)(u); 
1.163     brouard  1953: #ifdef DEBUG
                   1954:       /* f(x)=A(x-u)**2+f(u) */
                   1955:       double A, fparabu; 
                   1956:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1957:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1958:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1959:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1960:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1961:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1962:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1963:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1964: #endif 
1.184     brouard  1965: #ifdef MNBRAKORIGINAL
1.183     brouard  1966: #else
1.191     brouard  1967: /*       if (fu > *fc) { */
                   1968: /* #ifdef DEBUG */
                   1969: /*       printf("mnbrak4  fu > fc \n"); */
                   1970: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1971: /* #endif */
                   1972: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1973: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1974: /*     dum=u; /\* Shifting c and u *\/ */
                   1975: /*     u = *cx; */
                   1976: /*     *cx = dum; */
                   1977: /*     dum = fu; */
                   1978: /*     fu = *fc; */
                   1979: /*     *fc =dum; */
                   1980: /*       } else { /\* end *\/ */
                   1981: /* #ifdef DEBUG */
                   1982: /*       printf("mnbrak3  fu < fc \n"); */
                   1983: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1984: /* #endif */
                   1985: /*     dum=u; /\* Shifting c and u *\/ */
                   1986: /*     u = *cx; */
                   1987: /*     *cx = dum; */
                   1988: /*     dum = fu; */
                   1989: /*     fu = *fc; */
                   1990: /*     *fc =dum; */
                   1991: /*       } */
1.224     brouard  1992: #ifdef DEBUGMNBRAK
                   1993:                 double A, fparabu; 
                   1994:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1995:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1996:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1997:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1998: #endif
1.191     brouard  1999:       dum=u; /* Shifting c and u */
                   2000:       u = *cx;
                   2001:       *cx = dum;
                   2002:       dum = fu;
                   2003:       fu = *fc;
                   2004:       *fc =dum;
1.183     brouard  2005: #endif
1.162     brouard  2006:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2007: #ifdef DEBUG
1.224     brouard  2008:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2009:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2010: #endif
1.126     brouard  2011:       fu=(*func)(u); 
                   2012:       if (fu < *fc) { 
1.183     brouard  2013: #ifdef DEBUG
1.224     brouard  2014:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2015:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2016: #endif
                   2017:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2018:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2019: #ifdef DEBUG
                   2020:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2021: #endif
                   2022:       } 
1.162     brouard  2023:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2024: #ifdef DEBUG
1.224     brouard  2025:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2026:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2027: #endif
1.126     brouard  2028:       u=ulim; 
                   2029:       fu=(*func)(u); 
1.183     brouard  2030:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2031: #ifdef DEBUG
1.224     brouard  2032:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2033:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2034: #endif
1.126     brouard  2035:       u=(*cx)+GOLD*(*cx-*bx); 
                   2036:       fu=(*func)(u); 
1.224     brouard  2037: #ifdef DEBUG
                   2038:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2039:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2040: #endif
1.183     brouard  2041:     } /* end tests */
1.126     brouard  2042:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2043:     SHFT(*fa,*fb,*fc,fu) 
                   2044: #ifdef DEBUG
1.224     brouard  2045:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2046:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2047: #endif
                   2048:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2049: } 
                   2050: 
                   2051: /*************** linmin ************************/
1.162     brouard  2052: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2053: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2054: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2055: the value of func at the returned location p . This is actually all accomplished by calling the
                   2056: routines mnbrak and brent .*/
1.126     brouard  2057: int ncom; 
                   2058: double *pcom,*xicom;
                   2059: double (*nrfunc)(double []); 
                   2060:  
1.224     brouard  2061: #ifdef LINMINORIGINAL
1.126     brouard  2062: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2063: #else
                   2064: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2065: #endif
1.126     brouard  2066: { 
                   2067:   double brent(double ax, double bx, double cx, 
                   2068:               double (*f)(double), double tol, double *xmin); 
                   2069:   double f1dim(double x); 
                   2070:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2071:              double *fc, double (*func)(double)); 
                   2072:   int j; 
                   2073:   double xx,xmin,bx,ax; 
                   2074:   double fx,fb,fa;
1.187     brouard  2075: 
1.203     brouard  2076: #ifdef LINMINORIGINAL
                   2077: #else
                   2078:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2079: #endif
                   2080:   
1.126     brouard  2081:   ncom=n; 
                   2082:   pcom=vector(1,n); 
                   2083:   xicom=vector(1,n); 
                   2084:   nrfunc=func; 
                   2085:   for (j=1;j<=n;j++) { 
                   2086:     pcom[j]=p[j]; 
1.202     brouard  2087:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2088:   } 
1.187     brouard  2089: 
1.203     brouard  2090: #ifdef LINMINORIGINAL
                   2091:   xx=1.;
                   2092: #else
                   2093:   axs=0.0;
                   2094:   xxs=1.;
                   2095:   do{
                   2096:     xx= xxs;
                   2097: #endif
1.187     brouard  2098:     ax=0.;
                   2099:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2100:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2101:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2102:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2103:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2104:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2105:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2106: #ifdef LINMINORIGINAL
                   2107: #else
                   2108:     if (fx != fx){
1.224     brouard  2109:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2110:                        printf("|");
                   2111:                        fprintf(ficlog,"|");
1.203     brouard  2112: #ifdef DEBUGLINMIN
1.224     brouard  2113:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2114: #endif
                   2115:     }
1.224     brouard  2116:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2117: #endif
                   2118:   
1.191     brouard  2119: #ifdef DEBUGLINMIN
                   2120:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2121:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2122: #endif
1.224     brouard  2123: #ifdef LINMINORIGINAL
                   2124: #else
                   2125:        if(fb == fx){ /* Flat function in the direction */
                   2126:                xmin=xx;
                   2127:     *flat=1;
                   2128:        }else{
                   2129:     *flat=0;
                   2130: #endif
                   2131:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2132:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2133:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2134:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2135:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2136:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2137: #ifdef DEBUG
1.224     brouard  2138:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2139:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2140: #endif
                   2141: #ifdef LINMINORIGINAL
                   2142: #else
                   2143:                        }
1.126     brouard  2144: #endif
1.191     brouard  2145: #ifdef DEBUGLINMIN
                   2146:   printf("linmin end ");
1.202     brouard  2147:   fprintf(ficlog,"linmin end ");
1.191     brouard  2148: #endif
1.126     brouard  2149:   for (j=1;j<=n;j++) { 
1.203     brouard  2150: #ifdef LINMINORIGINAL
                   2151:     xi[j] *= xmin; 
                   2152: #else
                   2153: #ifdef DEBUGLINMIN
                   2154:     if(xxs <1.0)
                   2155:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2156: #endif
                   2157:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2158: #ifdef DEBUGLINMIN
                   2159:     if(xxs <1.0)
                   2160:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2161: #endif
                   2162: #endif
1.187     brouard  2163:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2164:   } 
1.191     brouard  2165: #ifdef DEBUGLINMIN
1.203     brouard  2166:   printf("\n");
1.191     brouard  2167:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2168:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2169:   for (j=1;j<=n;j++) { 
1.202     brouard  2170:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2171:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2172:     if(j % ncovmodel == 0){
1.191     brouard  2173:       printf("\n");
1.202     brouard  2174:       fprintf(ficlog,"\n");
                   2175:     }
1.191     brouard  2176:   }
1.203     brouard  2177: #else
1.191     brouard  2178: #endif
1.126     brouard  2179:   free_vector(xicom,1,n); 
                   2180:   free_vector(pcom,1,n); 
                   2181: } 
                   2182: 
                   2183: 
                   2184: /*************** powell ************************/
1.162     brouard  2185: /*
                   2186: Minimization of a function func of n variables. Input consists of an initial starting point
                   2187: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2188: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2189: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2190: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2191: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2192:  */
1.224     brouard  2193: #ifdef LINMINORIGINAL
                   2194: #else
                   2195:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2196:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2197: #endif
1.126     brouard  2198: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2199:            double (*func)(double [])) 
                   2200: { 
1.224     brouard  2201: #ifdef LINMINORIGINAL
                   2202:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2203:              double (*func)(double [])); 
1.224     brouard  2204: #else 
1.241     brouard  2205:  void linmin(double p[], double xi[], int n, double *fret,
                   2206:             double (*func)(double []),int *flat); 
1.224     brouard  2207: #endif
1.239     brouard  2208:  int i,ibig,j,jk,k; 
1.126     brouard  2209:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2210:   double directest;
1.126     brouard  2211:   double fp,fptt;
                   2212:   double *xits;
                   2213:   int niterf, itmp;
1.224     brouard  2214: #ifdef LINMINORIGINAL
                   2215: #else
                   2216: 
                   2217:   flatdir=ivector(1,n); 
                   2218:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2219: #endif
1.126     brouard  2220: 
                   2221:   pt=vector(1,n); 
                   2222:   ptt=vector(1,n); 
                   2223:   xit=vector(1,n); 
                   2224:   xits=vector(1,n); 
                   2225:   *fret=(*func)(p); 
                   2226:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2227:   rcurr_time = time(NULL);  
1.126     brouard  2228:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2229:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2230:     ibig=0; 
                   2231:     del=0.0; 
1.157     brouard  2232:     rlast_time=rcurr_time;
                   2233:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2234:     rcurr_time = time(NULL);  
                   2235:     curr_time = *localtime(&rcurr_time);
                   2236:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2237:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2238: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2239:     for (i=1;i<=n;i++) {
1.126     brouard  2240:       fprintf(ficrespow," %.12lf", p[i]);
                   2241:     }
1.239     brouard  2242:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2243:     printf("\n#model=  1      +     age ");
                   2244:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2245:     if(nagesqr==1){
1.241     brouard  2246:        printf("  + age*age  ");
                   2247:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2248:     }
                   2249:     for(j=1;j <=ncovmodel-2;j++){
                   2250:       if(Typevar[j]==0) {
                   2251:        printf("  +      V%d  ",Tvar[j]);
                   2252:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2253:       }else if(Typevar[j]==1) {
                   2254:        printf("  +    V%d*age ",Tvar[j]);
                   2255:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2256:       }else if(Typevar[j]==2) {
                   2257:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2258:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2259:       }
                   2260:     }
1.126     brouard  2261:     printf("\n");
1.239     brouard  2262: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2263: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2264:     fprintf(ficlog,"\n");
1.239     brouard  2265:     for(i=1,jk=1; i <=nlstate; i++){
                   2266:       for(k=1; k <=(nlstate+ndeath); k++){
                   2267:        if (k != i) {
                   2268:          printf("%d%d ",i,k);
                   2269:          fprintf(ficlog,"%d%d ",i,k);
                   2270:          for(j=1; j <=ncovmodel; j++){
                   2271:            printf("%12.7f ",p[jk]);
                   2272:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2273:            jk++; 
                   2274:          }
                   2275:          printf("\n");
                   2276:          fprintf(ficlog,"\n");
                   2277:        }
                   2278:       }
                   2279:     }
1.241     brouard  2280:     if(*iter <=3 && *iter >1){
1.157     brouard  2281:       tml = *localtime(&rcurr_time);
                   2282:       strcpy(strcurr,asctime(&tml));
                   2283:       rforecast_time=rcurr_time; 
1.126     brouard  2284:       itmp = strlen(strcurr);
                   2285:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2286:        strcurr[itmp-1]='\0';
1.162     brouard  2287:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2288:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2289:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2290:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2291:        forecast_time = *localtime(&rforecast_time);
                   2292:        strcpy(strfor,asctime(&forecast_time));
                   2293:        itmp = strlen(strfor);
                   2294:        if(strfor[itmp-1]=='\n')
                   2295:          strfor[itmp-1]='\0';
                   2296:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2297:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2298:       }
                   2299:     }
1.187     brouard  2300:     for (i=1;i<=n;i++) { /* For each direction i */
                   2301:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2302:       fptt=(*fret); 
                   2303: #ifdef DEBUG
1.203     brouard  2304:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2305:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2306: #endif
1.203     brouard  2307:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2308:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2309: #ifdef LINMINORIGINAL
1.188     brouard  2310:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2311: #else
                   2312:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2313:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2314: #endif
                   2315:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2316:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2317:                                /* because that direction will be replaced unless the gain del is small */
                   2318:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2319:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2320:                                /* with the new direction. */
                   2321:                                del=fabs(fptt-(*fret)); 
                   2322:                                ibig=i; 
1.126     brouard  2323:       } 
                   2324: #ifdef DEBUG
                   2325:       printf("%d %.12e",i,(*fret));
                   2326:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2327:       for (j=1;j<=n;j++) {
1.224     brouard  2328:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2329:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2330:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2331:       }
                   2332:       for(j=1;j<=n;j++) {
1.225     brouard  2333:                                printf(" p(%d)=%.12e",j,p[j]);
                   2334:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2335:       }
                   2336:       printf("\n");
                   2337:       fprintf(ficlog,"\n");
                   2338: #endif
1.187     brouard  2339:     } /* end loop on each direction i */
                   2340:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2341:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2342:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2343:       for(j=1;j<=n;j++) {
1.225     brouard  2344:                                if(flatdir[j] >0){
                   2345:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2346:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2347:                                }
                   2348:                                /* printf("\n"); */
                   2349:                                /* fprintf(ficlog,"\n"); */
                   2350:                        }
1.243     brouard  2351:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2352:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2353:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2354:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2355:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2356:       /* decreased of more than 3.84  */
                   2357:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2358:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2359:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2360:                        
1.188     brouard  2361:       /* Starting the program with initial values given by a former maximization will simply change */
                   2362:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2363:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2364:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2365: #ifdef DEBUG
                   2366:       int k[2],l;
                   2367:       k[0]=1;
                   2368:       k[1]=-1;
                   2369:       printf("Max: %.12e",(*func)(p));
                   2370:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2371:       for (j=1;j<=n;j++) {
                   2372:        printf(" %.12e",p[j]);
                   2373:        fprintf(ficlog," %.12e",p[j]);
                   2374:       }
                   2375:       printf("\n");
                   2376:       fprintf(ficlog,"\n");
                   2377:       for(l=0;l<=1;l++) {
                   2378:        for (j=1;j<=n;j++) {
                   2379:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2380:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2381:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2382:        }
                   2383:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2384:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2385:       }
                   2386: #endif
                   2387: 
1.224     brouard  2388: #ifdef LINMINORIGINAL
                   2389: #else
                   2390:       free_ivector(flatdir,1,n); 
                   2391: #endif
1.126     brouard  2392:       free_vector(xit,1,n); 
                   2393:       free_vector(xits,1,n); 
                   2394:       free_vector(ptt,1,n); 
                   2395:       free_vector(pt,1,n); 
                   2396:       return; 
1.192     brouard  2397:     } /* enough precision */ 
1.240     brouard  2398:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2399:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2400:       ptt[j]=2.0*p[j]-pt[j]; 
                   2401:       xit[j]=p[j]-pt[j]; 
                   2402:       pt[j]=p[j]; 
                   2403:     } 
1.181     brouard  2404:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2405: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2406:                if (*iter <=4) {
1.225     brouard  2407: #else
                   2408: #endif
1.224     brouard  2409: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2410: #else
1.161     brouard  2411:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2412: #endif
1.162     brouard  2413:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2414:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2415:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2416:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2417:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2418:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2419:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2420:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2421:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2422:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2423:       /* mu² and del² are equal when f3=f1 */
                   2424:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2425:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2426:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2427:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2428: #ifdef NRCORIGINAL
                   2429:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2430: #else
                   2431:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2432:       t= t- del*SQR(fp-fptt);
1.183     brouard  2433: #endif
1.202     brouard  2434:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2435: #ifdef DEBUG
1.181     brouard  2436:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2437:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2438:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2439:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2440:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2441:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2442:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2443:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2444: #endif
1.183     brouard  2445: #ifdef POWELLORIGINAL
                   2446:       if (t < 0.0) { /* Then we use it for new direction */
                   2447: #else
1.182     brouard  2448:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2449:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2450:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2451:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2452:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2453:       } 
1.181     brouard  2454:       if (directest < 0.0) { /* Then we use it for new direction */
                   2455: #endif
1.191     brouard  2456: #ifdef DEBUGLINMIN
1.234     brouard  2457:        printf("Before linmin in direction P%d-P0\n",n);
                   2458:        for (j=1;j<=n;j++) {
                   2459:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2460:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2461:          if(j % ncovmodel == 0){
                   2462:            printf("\n");
                   2463:            fprintf(ficlog,"\n");
                   2464:          }
                   2465:        }
1.224     brouard  2466: #endif
                   2467: #ifdef LINMINORIGINAL
1.234     brouard  2468:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2469: #else
1.234     brouard  2470:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2471:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2472: #endif
1.234     brouard  2473:        
1.191     brouard  2474: #ifdef DEBUGLINMIN
1.234     brouard  2475:        for (j=1;j<=n;j++) { 
                   2476:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2477:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2478:          if(j % ncovmodel == 0){
                   2479:            printf("\n");
                   2480:            fprintf(ficlog,"\n");
                   2481:          }
                   2482:        }
1.224     brouard  2483: #endif
1.234     brouard  2484:        for (j=1;j<=n;j++) { 
                   2485:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2486:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2487:        }
1.224     brouard  2488: #ifdef LINMINORIGINAL
                   2489: #else
1.234     brouard  2490:        for (j=1, flatd=0;j<=n;j++) {
                   2491:          if(flatdir[j]>0)
                   2492:            flatd++;
                   2493:        }
                   2494:        if(flatd >0){
1.255     brouard  2495:          printf("%d flat directions: ",flatd);
                   2496:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2497:          for (j=1;j<=n;j++) { 
                   2498:            if(flatdir[j]>0){
                   2499:              printf("%d ",j);
                   2500:              fprintf(ficlog,"%d ",j);
                   2501:            }
                   2502:          }
                   2503:          printf("\n");
                   2504:          fprintf(ficlog,"\n");
                   2505:        }
1.191     brouard  2506: #endif
1.234     brouard  2507:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2508:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2509:        
1.126     brouard  2510: #ifdef DEBUG
1.234     brouard  2511:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2512:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2513:        for(j=1;j<=n;j++){
                   2514:          printf(" %lf",xit[j]);
                   2515:          fprintf(ficlog," %lf",xit[j]);
                   2516:        }
                   2517:        printf("\n");
                   2518:        fprintf(ficlog,"\n");
1.126     brouard  2519: #endif
1.192     brouard  2520:       } /* end of t or directest negative */
1.224     brouard  2521: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2522: #else
1.234     brouard  2523:       } /* end if (fptt < fp)  */
1.192     brouard  2524: #endif
1.225     brouard  2525: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2526:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2527: #else
1.224     brouard  2528: #endif
1.234     brouard  2529:                } /* loop iteration */ 
1.126     brouard  2530: } 
1.234     brouard  2531:   
1.126     brouard  2532: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2533:   
1.235     brouard  2534:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2535:   {
1.279     brouard  2536:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2537:      *   (and selected quantitative values in nres)
                   2538:      *  by left multiplying the unit
                   2539:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2540:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2541:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2542:      * or prevalence in state 1, prevalence in state 2, 0
                   2543:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2544:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2545:      * Output is prlim.
                   2546:      * Initial matrix pimij 
                   2547:      */
1.206     brouard  2548:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2549:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2550:   /*  0,                   0                  , 1} */
                   2551:   /*
                   2552:    * and after some iteration: */
                   2553:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2554:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2555:   /*  0,                   0                  , 1} */
                   2556:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2557:   /* {0.51571254859325999, 0.4842874514067399, */
                   2558:   /*  0.51326036147820708, 0.48673963852179264} */
                   2559:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2560:     
1.126     brouard  2561:   int i, ii,j,k;
1.209     brouard  2562:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2563:   /* double **matprod2(); */ /* test */
1.218     brouard  2564:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2565:   double **newm;
1.209     brouard  2566:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2567:   int ncvloop=0;
1.169     brouard  2568:   
1.209     brouard  2569:   min=vector(1,nlstate);
                   2570:   max=vector(1,nlstate);
                   2571:   meandiff=vector(1,nlstate);
                   2572: 
1.218     brouard  2573:        /* Starting with matrix unity */
1.126     brouard  2574:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2575:     for (j=1;j<=nlstate+ndeath;j++){
                   2576:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2577:     }
1.169     brouard  2578:   
                   2579:   cov[1]=1.;
                   2580:   
                   2581:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2582:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2583:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2584:     ncvloop++;
1.126     brouard  2585:     newm=savm;
                   2586:     /* Covariates have to be included here again */
1.138     brouard  2587:     cov[2]=agefin;
1.187     brouard  2588:     if(nagesqr==1)
                   2589:       cov[3]= agefin*agefin;;
1.234     brouard  2590:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2591:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2592:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2593:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2594:     }
                   2595:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2596:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2597:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2598:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2599:     }
1.237     brouard  2600:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2601:       if(Dummy[Tvar[Tage[k]]]){
                   2602:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2603:       } else{
1.235     brouard  2604:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2605:       }
1.235     brouard  2606:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2607:     }
1.237     brouard  2608:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2609:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2610:       if(Dummy[Tvard[k][1]==0]){
                   2611:        if(Dummy[Tvard[k][2]==0]){
                   2612:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2613:        }else{
                   2614:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2615:        }
                   2616:       }else{
                   2617:        if(Dummy[Tvard[k][2]==0]){
                   2618:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2619:        }else{
                   2620:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2621:        }
                   2622:       }
1.234     brouard  2623:     }
1.138     brouard  2624:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2625:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2626:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2627:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2628:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2629:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2630:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2631:     
1.126     brouard  2632:     savm=oldm;
                   2633:     oldm=newm;
1.209     brouard  2634: 
                   2635:     for(j=1; j<=nlstate; j++){
                   2636:       max[j]=0.;
                   2637:       min[j]=1.;
                   2638:     }
                   2639:     for(i=1;i<=nlstate;i++){
                   2640:       sumnew=0;
                   2641:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2642:       for(j=1; j<=nlstate; j++){ 
                   2643:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2644:        max[j]=FMAX(max[j],prlim[i][j]);
                   2645:        min[j]=FMIN(min[j],prlim[i][j]);
                   2646:       }
                   2647:     }
                   2648: 
1.126     brouard  2649:     maxmax=0.;
1.209     brouard  2650:     for(j=1; j<=nlstate; j++){
                   2651:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2652:       maxmax=FMAX(maxmax,meandiff[j]);
                   2653:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2654:     } /* j loop */
1.203     brouard  2655:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2656:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2657:     if(maxmax < ftolpl){
1.209     brouard  2658:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2659:       free_vector(min,1,nlstate);
                   2660:       free_vector(max,1,nlstate);
                   2661:       free_vector(meandiff,1,nlstate);
1.126     brouard  2662:       return prlim;
                   2663:     }
1.169     brouard  2664:   } /* age loop */
1.208     brouard  2665:     /* After some age loop it doesn't converge */
1.209     brouard  2666:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2667: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2668:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2669:   free_vector(min,1,nlstate);
                   2670:   free_vector(max,1,nlstate);
                   2671:   free_vector(meandiff,1,nlstate);
1.208     brouard  2672:   
1.169     brouard  2673:   return prlim; /* should not reach here */
1.126     brouard  2674: }
                   2675: 
1.217     brouard  2676: 
                   2677:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2678: 
1.218     brouard  2679:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2680:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2681:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2682: {
1.264     brouard  2683:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2684:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2685:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2686:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2687:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2688:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2689:   /* Initial matrix pimij */
                   2690:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2691:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2692:   /*  0,                   0                  , 1} */
                   2693:   /*
                   2694:    * and after some iteration: */
                   2695:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2696:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2697:   /*  0,                   0                  , 1} */
                   2698:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2699:   /* {0.51571254859325999, 0.4842874514067399, */
                   2700:   /*  0.51326036147820708, 0.48673963852179264} */
                   2701:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2702: 
                   2703:   int i, ii,j,k;
1.247     brouard  2704:   int first=0;
1.217     brouard  2705:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2706:   /* double **matprod2(); */ /* test */
                   2707:   double **out, cov[NCOVMAX+1], **bmij();
                   2708:   double **newm;
1.218     brouard  2709:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2710:   double        **oldm, **savm;  /* for use */
                   2711: 
1.217     brouard  2712:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2713:   int ncvloop=0;
                   2714:   
                   2715:   min=vector(1,nlstate);
                   2716:   max=vector(1,nlstate);
                   2717:   meandiff=vector(1,nlstate);
                   2718: 
1.266     brouard  2719:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2720:   oldm=oldms; savm=savms;
                   2721:   
                   2722:   /* Starting with matrix unity */
                   2723:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2724:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2725:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2726:     }
                   2727:   
                   2728:   cov[1]=1.;
                   2729:   
                   2730:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2731:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2732:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2733:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2734:     ncvloop++;
1.218     brouard  2735:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2736:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2737:     /* Covariates have to be included here again */
                   2738:     cov[2]=agefin;
                   2739:     if(nagesqr==1)
                   2740:       cov[3]= agefin*agefin;;
1.242     brouard  2741:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2742:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2743:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2744:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2745:     }
                   2746:     /* for (k=1; k<=cptcovn;k++) { */
                   2747:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2748:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2749:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2750:     /* } */
                   2751:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2752:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2753:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2754:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2755:     }
                   2756:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2757:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2758:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2759:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2760:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2761:       if(Dummy[Tvar[Tage[k]]]){
                   2762:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2763:       } else{
                   2764:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2765:       }
                   2766:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2767:     }
                   2768:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2769:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2770:       if(Dummy[Tvard[k][1]==0]){
                   2771:        if(Dummy[Tvard[k][2]==0]){
                   2772:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2773:        }else{
                   2774:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2775:        }
                   2776:       }else{
                   2777:        if(Dummy[Tvard[k][2]==0]){
                   2778:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2779:        }else{
                   2780:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2781:        }
                   2782:       }
1.217     brouard  2783:     }
                   2784:     
                   2785:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2786:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2787:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2788:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2789:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2790:                /* ij should be linked to the correct index of cov */
                   2791:                /* age and covariate values ij are in 'cov', but we need to pass
                   2792:                 * ij for the observed prevalence at age and status and covariate
                   2793:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2794:                 */
                   2795:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2796:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2797:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2798:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2799:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2800:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2801:     /*         printf("%d newm= ",i); */
                   2802:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2803:     /*           printf("%f ",newm[i][j]); */
                   2804:     /*         } */
                   2805:     /*         printf("oldm * "); */
                   2806:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2807:     /*           printf("%f ",oldm[i][j]); */
                   2808:     /*         } */
1.268     brouard  2809:     /*         printf(" bmmij "); */
1.266     brouard  2810:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2811:     /*           printf("%f ",pmmij[i][j]); */
                   2812:     /*         } */
                   2813:     /*         printf("\n"); */
                   2814:     /*   } */
                   2815:     /* } */
1.217     brouard  2816:     savm=oldm;
                   2817:     oldm=newm;
1.266     brouard  2818: 
1.217     brouard  2819:     for(j=1; j<=nlstate; j++){
                   2820:       max[j]=0.;
                   2821:       min[j]=1.;
                   2822:     }
                   2823:     for(j=1; j<=nlstate; j++){ 
                   2824:       for(i=1;i<=nlstate;i++){
1.234     brouard  2825:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2826:        bprlim[i][j]= newm[i][j];
                   2827:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2828:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2829:       }
                   2830:     }
1.218     brouard  2831:                
1.217     brouard  2832:     maxmax=0.;
                   2833:     for(i=1; i<=nlstate; i++){
                   2834:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2835:       maxmax=FMAX(maxmax,meandiff[i]);
                   2836:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2837:     } /* i loop */
1.217     brouard  2838:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2839:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2840:     if(maxmax < ftolpl){
1.220     brouard  2841:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2842:       free_vector(min,1,nlstate);
                   2843:       free_vector(max,1,nlstate);
                   2844:       free_vector(meandiff,1,nlstate);
                   2845:       return bprlim;
                   2846:     }
                   2847:   } /* age loop */
                   2848:     /* After some age loop it doesn't converge */
1.247     brouard  2849:   if(first){
                   2850:     first=1;
                   2851:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2852: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2853:   }
                   2854:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2855: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2856:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2857:   free_vector(min,1,nlstate);
                   2858:   free_vector(max,1,nlstate);
                   2859:   free_vector(meandiff,1,nlstate);
                   2860:   
                   2861:   return bprlim; /* should not reach here */
                   2862: }
                   2863: 
1.126     brouard  2864: /*************** transition probabilities ***************/ 
                   2865: 
                   2866: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2867: {
1.138     brouard  2868:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2869:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2870:      model to the ncovmodel covariates (including constant and age).
                   2871:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2872:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2873:      ncth covariate in the global vector x is given by the formula:
                   2874:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2875:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2876:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2877:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2878:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2879:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2880:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2881:   */
                   2882:   double s1, lnpijopii;
1.126     brouard  2883:   /*double t34;*/
1.164     brouard  2884:   int i,j, nc, ii, jj;
1.126     brouard  2885: 
1.223     brouard  2886:   for(i=1; i<= nlstate; i++){
                   2887:     for(j=1; j<i;j++){
                   2888:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2889:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2890:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2891:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2892:       }
                   2893:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2894:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2895:     }
                   2896:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2897:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2898:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2899:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2900:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2901:       }
                   2902:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2903:     }
                   2904:   }
1.218     brouard  2905:   
1.223     brouard  2906:   for(i=1; i<= nlstate; i++){
                   2907:     s1=0;
                   2908:     for(j=1; j<i; j++){
                   2909:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2910:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2911:     }
                   2912:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2913:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2914:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2915:     }
                   2916:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2917:     ps[i][i]=1./(s1+1.);
                   2918:     /* Computing other pijs */
                   2919:     for(j=1; j<i; j++)
                   2920:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2921:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2922:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2923:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2924:   } /* end i */
1.218     brouard  2925:   
1.223     brouard  2926:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2927:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2928:       ps[ii][jj]=0;
                   2929:       ps[ii][ii]=1;
                   2930:     }
                   2931:   }
1.218     brouard  2932:   
                   2933:   
1.223     brouard  2934:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2935:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2936:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2937:   /*   } */
                   2938:   /*   printf("\n "); */
                   2939:   /* } */
                   2940:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2941:   /*
                   2942:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2943:                goto end;*/
1.266     brouard  2944:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2945: }
                   2946: 
1.218     brouard  2947: /*************** backward transition probabilities ***************/ 
                   2948: 
                   2949:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2950: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2951:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2952: {
1.266     brouard  2953:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2954:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2955:    */
1.218     brouard  2956:   int i, ii, j,k;
1.222     brouard  2957:   
                   2958:   double **out, **pmij();
                   2959:   double sumnew=0.;
1.218     brouard  2960:   double agefin;
1.268     brouard  2961:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2962:   double **dnewm, **dsavm, **doldm;
                   2963:   double **bbmij;
                   2964:   
1.218     brouard  2965:   doldm=ddoldms; /* global pointers */
1.222     brouard  2966:   dnewm=ddnewms;
                   2967:   dsavm=ddsavms;
                   2968:   
                   2969:   agefin=cov[2];
1.268     brouard  2970:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2971:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2972:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2973:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2974: 
                   2975:   /* P_x */
1.266     brouard  2976:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2977:   /* outputs pmmij which is a stochastic matrix in row */
                   2978: 
                   2979:   /* Diag(w_x) */
                   2980:   /* Problem with prevacurrent which can be zero */
                   2981:   sumnew=0.;
1.269     brouard  2982:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2983:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2984:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2985:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2986:   }
                   2987:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2988:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2989:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2990:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2991:     }
                   2992:   }else{
                   2993:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2994:       for (j=1;j<=nlstate+ndeath;j++)
                   2995:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2996:     }
                   2997:     /* if(sumnew <0.9){ */
                   2998:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2999:     /* } */
                   3000:   }
                   3001:   k3=0.0;  /* We put the last diagonal to 0 */
                   3002:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3003:       doldm[ii][ii]= k3;
                   3004:   }
                   3005:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3006:   
                   3007:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3008:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3009: 
                   3010:   /* Diag(Sum_i w^i_x p^ij_x */
                   3011:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3012:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3013:     sumnew=0.;
1.222     brouard  3014:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3015:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3016:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3017:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3018:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3019:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3020:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3021:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3022:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3023:        /* }else */
1.268     brouard  3024:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3025:     } /*End ii */
                   3026:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3027: 
                   3028:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3029:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3030:   /* end bmij */
1.266     brouard  3031:   return ps; /*pointer is unchanged */
1.218     brouard  3032: }
1.217     brouard  3033: /*************** transition probabilities ***************/ 
                   3034: 
1.218     brouard  3035: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3036: {
                   3037:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3038:      computes the probability to be observed in state j being in state i by appying the
                   3039:      model to the ncovmodel covariates (including constant and age).
                   3040:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3041:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3042:      ncth covariate in the global vector x is given by the formula:
                   3043:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3044:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3045:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3046:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3047:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3048:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3049:   */
                   3050:   double s1, lnpijopii;
                   3051:   /*double t34;*/
                   3052:   int i,j, nc, ii, jj;
                   3053: 
1.234     brouard  3054:   for(i=1; i<= nlstate; i++){
                   3055:     for(j=1; j<i;j++){
                   3056:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3057:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3058:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3059:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3060:       }
                   3061:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3062:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3063:     }
                   3064:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3065:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3066:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3067:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3068:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3069:       }
                   3070:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3071:     }
                   3072:   }
                   3073:   
                   3074:   for(i=1; i<= nlstate; i++){
                   3075:     s1=0;
                   3076:     for(j=1; j<i; j++){
                   3077:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3078:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3079:     }
                   3080:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3081:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3082:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3083:     }
                   3084:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3085:     ps[i][i]=1./(s1+1.);
                   3086:     /* Computing other pijs */
                   3087:     for(j=1; j<i; j++)
                   3088:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3089:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3090:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3091:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3092:   } /* end i */
                   3093:   
                   3094:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3095:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3096:       ps[ii][jj]=0;
                   3097:       ps[ii][ii]=1;
                   3098:     }
                   3099:   }
                   3100:   /* Added for backcast */ /* Transposed matrix too */
                   3101:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3102:     s1=0.;
                   3103:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3104:       s1+=ps[ii][jj];
                   3105:     }
                   3106:     for(ii=1; ii<= nlstate; ii++){
                   3107:       ps[ii][jj]=ps[ii][jj]/s1;
                   3108:     }
                   3109:   }
                   3110:   /* Transposition */
                   3111:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3112:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3113:       s1=ps[ii][jj];
                   3114:       ps[ii][jj]=ps[jj][ii];
                   3115:       ps[jj][ii]=s1;
                   3116:     }
                   3117:   }
                   3118:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3119:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3120:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3121:   /*   } */
                   3122:   /*   printf("\n "); */
                   3123:   /* } */
                   3124:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3125:   /*
                   3126:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3127:     goto end;*/
                   3128:   return ps;
1.217     brouard  3129: }
                   3130: 
                   3131: 
1.126     brouard  3132: /**************** Product of 2 matrices ******************/
                   3133: 
1.145     brouard  3134: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3135: {
                   3136:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3137:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3138:   /* in, b, out are matrice of pointers which should have been initialized 
                   3139:      before: only the contents of out is modified. The function returns
                   3140:      a pointer to pointers identical to out */
1.145     brouard  3141:   int i, j, k;
1.126     brouard  3142:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3143:     for(k=ncolol; k<=ncoloh; k++){
                   3144:       out[i][k]=0.;
                   3145:       for(j=ncl; j<=nch; j++)
                   3146:        out[i][k] +=in[i][j]*b[j][k];
                   3147:     }
1.126     brouard  3148:   return out;
                   3149: }
                   3150: 
                   3151: 
                   3152: /************* Higher Matrix Product ***************/
                   3153: 
1.235     brouard  3154: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3155: {
1.218     brouard  3156:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3157:      'nhstepm*hstepm*stepm' months (i.e. until
                   3158:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3159:      nhstepm*hstepm matrices. 
                   3160:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3161:      (typically every 2 years instead of every month which is too big 
                   3162:      for the memory).
                   3163:      Model is determined by parameters x and covariates have to be 
                   3164:      included manually here. 
                   3165: 
                   3166:      */
                   3167: 
                   3168:   int i, j, d, h, k;
1.131     brouard  3169:   double **out, cov[NCOVMAX+1];
1.126     brouard  3170:   double **newm;
1.187     brouard  3171:   double agexact;
1.214     brouard  3172:   double agebegin, ageend;
1.126     brouard  3173: 
                   3174:   /* Hstepm could be zero and should return the unit matrix */
                   3175:   for (i=1;i<=nlstate+ndeath;i++)
                   3176:     for (j=1;j<=nlstate+ndeath;j++){
                   3177:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3178:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3179:     }
                   3180:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3181:   for(h=1; h <=nhstepm; h++){
                   3182:     for(d=1; d <=hstepm; d++){
                   3183:       newm=savm;
                   3184:       /* Covariates have to be included here again */
                   3185:       cov[1]=1.;
1.214     brouard  3186:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3187:       cov[2]=agexact;
                   3188:       if(nagesqr==1)
1.227     brouard  3189:        cov[3]= agexact*agexact;
1.235     brouard  3190:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3191:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3192:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3193:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3194:       }
                   3195:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3196:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3197:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3198:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3199:       }
                   3200:       for (k=1; k<=cptcovage;k++){
                   3201:        if(Dummy[Tvar[Tage[k]]]){
                   3202:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3203:        } else{
                   3204:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3205:        }
                   3206:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3207:       }
                   3208:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3209:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3210:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3211:       }
                   3212:       /* for (k=1; k<=cptcovn;k++)  */
                   3213:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3214:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3215:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3216:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3217:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3218:       
                   3219:       
1.126     brouard  3220:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3221:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3222:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3223:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3224:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3225:       /* if((int)age == 70){ */
                   3226:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3227:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3228:       /*         printf("%d pmmij ",i); */
                   3229:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3230:       /*           printf("%f ",pmmij[i][j]); */
                   3231:       /*         } */
                   3232:       /*         printf(" oldm "); */
                   3233:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3234:       /*           printf("%f ",oldm[i][j]); */
                   3235:       /*         } */
                   3236:       /*         printf("\n"); */
                   3237:       /*       } */
                   3238:       /* } */
1.126     brouard  3239:       savm=oldm;
                   3240:       oldm=newm;
                   3241:     }
                   3242:     for(i=1; i<=nlstate+ndeath; i++)
                   3243:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3244:        po[i][j][h]=newm[i][j];
                   3245:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3246:       }
1.128     brouard  3247:     /*printf("h=%d ",h);*/
1.126     brouard  3248:   } /* end h */
1.267     brouard  3249:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3250:   return po;
                   3251: }
                   3252: 
1.217     brouard  3253: /************* Higher Back Matrix Product ***************/
1.218     brouard  3254: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3255: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3256: {
1.266     brouard  3257:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3258:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3259:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3260:      nhstepm*hstepm matrices.
                   3261:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3262:      (typically every 2 years instead of every month which is too big
1.217     brouard  3263:      for the memory).
1.218     brouard  3264:      Model is determined by parameters x and covariates have to be
1.266     brouard  3265:      included manually here. Then we use a call to bmij(x and cov)
                   3266:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3267:   */
1.217     brouard  3268: 
                   3269:   int i, j, d, h, k;
1.266     brouard  3270:   double **out, cov[NCOVMAX+1], **bmij();
                   3271:   double **newm, ***newmm;
1.217     brouard  3272:   double agexact;
                   3273:   double agebegin, ageend;
1.222     brouard  3274:   double **oldm, **savm;
1.217     brouard  3275: 
1.266     brouard  3276:   newmm=po; /* To be saved */
                   3277:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3278:   /* Hstepm could be zero and should return the unit matrix */
                   3279:   for (i=1;i<=nlstate+ndeath;i++)
                   3280:     for (j=1;j<=nlstate+ndeath;j++){
                   3281:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3282:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3283:     }
                   3284:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3285:   for(h=1; h <=nhstepm; h++){
                   3286:     for(d=1; d <=hstepm; d++){
                   3287:       newm=savm;
                   3288:       /* Covariates have to be included here again */
                   3289:       cov[1]=1.;
1.271     brouard  3290:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3291:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3292:       cov[2]=agexact;
                   3293:       if(nagesqr==1)
1.222     brouard  3294:        cov[3]= agexact*agexact;
1.266     brouard  3295:       for (k=1; k<=cptcovn;k++){
                   3296:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3297:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3298:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3299:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3300:       }
1.267     brouard  3301:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3302:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3303:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3304:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3305:       }
                   3306:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3307:        if(Dummy[Tvar[Tage[k]]]){
                   3308:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3309:        } else{
                   3310:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3311:        }
                   3312:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3313:       }
                   3314:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3315:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3316:       }                        
1.217     brouard  3317:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3318:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3319: 
1.218     brouard  3320:       /* Careful transposed matrix */
1.266     brouard  3321:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3322:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3323:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3324:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3325:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3326:       /* if((int)age == 70){ */
                   3327:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3328:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3329:       /*         printf("%d pmmij ",i); */
                   3330:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3331:       /*           printf("%f ",pmmij[i][j]); */
                   3332:       /*         } */
                   3333:       /*         printf(" oldm "); */
                   3334:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3335:       /*           printf("%f ",oldm[i][j]); */
                   3336:       /*         } */
                   3337:       /*         printf("\n"); */
                   3338:       /*       } */
                   3339:       /* } */
                   3340:       savm=oldm;
                   3341:       oldm=newm;
                   3342:     }
                   3343:     for(i=1; i<=nlstate+ndeath; i++)
                   3344:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3345:        po[i][j][h]=newm[i][j];
1.268     brouard  3346:        /* if(h==nhstepm) */
                   3347:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3348:       }
1.268     brouard  3349:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3350:   } /* end h */
1.268     brouard  3351:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3352:   return po;
                   3353: }
                   3354: 
                   3355: 
1.162     brouard  3356: #ifdef NLOPT
                   3357:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3358:   double fret;
                   3359:   double *xt;
                   3360:   int j;
                   3361:   myfunc_data *d2 = (myfunc_data *) pd;
                   3362: /* xt = (p1-1); */
                   3363:   xt=vector(1,n); 
                   3364:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3365: 
                   3366:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3367:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3368:   printf("Function = %.12lf ",fret);
                   3369:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3370:   printf("\n");
                   3371:  free_vector(xt,1,n);
                   3372:   return fret;
                   3373: }
                   3374: #endif
1.126     brouard  3375: 
                   3376: /*************** log-likelihood *************/
                   3377: double func( double *x)
                   3378: {
1.226     brouard  3379:   int i, ii, j, k, mi, d, kk;
                   3380:   int ioffset=0;
                   3381:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3382:   double **out;
                   3383:   double lli; /* Individual log likelihood */
                   3384:   int s1, s2;
1.228     brouard  3385:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3386:   double bbh, survp;
                   3387:   long ipmx;
                   3388:   double agexact;
                   3389:   /*extern weight */
                   3390:   /* We are differentiating ll according to initial status */
                   3391:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3392:   /*for(i=1;i<imx;i++) 
                   3393:     printf(" %d\n",s[4][i]);
                   3394:   */
1.162     brouard  3395: 
1.226     brouard  3396:   ++countcallfunc;
1.162     brouard  3397: 
1.226     brouard  3398:   cov[1]=1.;
1.126     brouard  3399: 
1.226     brouard  3400:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3401:   ioffset=0;
1.226     brouard  3402:   if(mle==1){
                   3403:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3404:       /* Computes the values of the ncovmodel covariates of the model
                   3405:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3406:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3407:         to be observed in j being in i according to the model.
                   3408:       */
1.243     brouard  3409:       ioffset=2+nagesqr ;
1.233     brouard  3410:    /* Fixed */
1.234     brouard  3411:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3412:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3413:       }
1.226     brouard  3414:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3415:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3416:         has been calculated etc */
                   3417:       /* For an individual i, wav[i] gives the number of effective waves */
                   3418:       /* We compute the contribution to Likelihood of each effective transition
                   3419:         mw[mi][i] is real wave of the mi th effectve wave */
                   3420:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3421:         s2=s[mw[mi+1][i]][i];
                   3422:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3423:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3424:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3425:       */
                   3426:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3427:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3428:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3429:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3430:        }
                   3431:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3432:          for (j=1;j<=nlstate+ndeath;j++){
                   3433:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3434:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3435:          }
                   3436:        for(d=0; d<dh[mi][i]; d++){
                   3437:          newm=savm;
                   3438:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3439:          cov[2]=agexact;
                   3440:          if(nagesqr==1)
                   3441:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3442:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3443:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3444:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3445:          else
                   3446:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3447:          }
                   3448:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3449:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3450:          savm=oldm;
                   3451:          oldm=newm;
                   3452:        } /* end mult */
                   3453:        
                   3454:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3455:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3456:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3457:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3458:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3459:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3460:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3461:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3462:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3463:                                 * -stepm/2 to stepm/2 .
                   3464:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3465:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3466:                                 */
1.234     brouard  3467:        s1=s[mw[mi][i]][i];
                   3468:        s2=s[mw[mi+1][i]][i];
                   3469:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3470:        /* bias bh is positive if real duration
                   3471:         * is higher than the multiple of stepm and negative otherwise.
                   3472:         */
                   3473:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3474:        if( s2 > nlstate){ 
                   3475:          /* i.e. if s2 is a death state and if the date of death is known 
                   3476:             then the contribution to the likelihood is the probability to 
                   3477:             die between last step unit time and current  step unit time, 
                   3478:             which is also equal to probability to die before dh 
                   3479:             minus probability to die before dh-stepm . 
                   3480:             In version up to 0.92 likelihood was computed
                   3481:             as if date of death was unknown. Death was treated as any other
                   3482:             health state: the date of the interview describes the actual state
                   3483:             and not the date of a change in health state. The former idea was
                   3484:             to consider that at each interview the state was recorded
                   3485:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3486:             introduced the exact date of death then we should have modified
                   3487:             the contribution of an exact death to the likelihood. This new
                   3488:             contribution is smaller and very dependent of the step unit
                   3489:             stepm. It is no more the probability to die between last interview
                   3490:             and month of death but the probability to survive from last
                   3491:             interview up to one month before death multiplied by the
                   3492:             probability to die within a month. Thanks to Chris
                   3493:             Jackson for correcting this bug.  Former versions increased
                   3494:             mortality artificially. The bad side is that we add another loop
                   3495:             which slows down the processing. The difference can be up to 10%
                   3496:             lower mortality.
                   3497:          */
                   3498:          /* If, at the beginning of the maximization mostly, the
                   3499:             cumulative probability or probability to be dead is
                   3500:             constant (ie = 1) over time d, the difference is equal to
                   3501:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3502:             s1 at precedent wave, to be dead a month before current
                   3503:             wave is equal to probability, being at state s1 at
                   3504:             precedent wave, to be dead at mont of the current
                   3505:             wave. Then the observed probability (that this person died)
                   3506:             is null according to current estimated parameter. In fact,
                   3507:             it should be very low but not zero otherwise the log go to
                   3508:             infinity.
                   3509:          */
1.183     brouard  3510: /* #ifdef INFINITYORIGINAL */
                   3511: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3512: /* #else */
                   3513: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3514: /*         lli=log(mytinydouble); */
                   3515: /*       else */
                   3516: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3517: /* #endif */
1.226     brouard  3518:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3519:          
1.226     brouard  3520:        } else if  ( s2==-1 ) { /* alive */
                   3521:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3522:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3523:          /*survp += out[s1][j]; */
                   3524:          lli= log(survp);
                   3525:        }
                   3526:        else if  (s2==-4) { 
                   3527:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3528:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3529:          lli= log(survp); 
                   3530:        } 
                   3531:        else if  (s2==-5) { 
                   3532:          for (j=1,survp=0. ; j<=2; j++)  
                   3533:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3534:          lli= log(survp); 
                   3535:        } 
                   3536:        else{
                   3537:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3538:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3539:        } 
                   3540:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3541:        /*if(lli ==000.0)*/
                   3542:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3543:        ipmx +=1;
                   3544:        sw += weight[i];
                   3545:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3546:        /* if (lli < log(mytinydouble)){ */
                   3547:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3548:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3549:        /* } */
                   3550:       } /* end of wave */
                   3551:     } /* end of individual */
                   3552:   }  else if(mle==2){
                   3553:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3554:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3555:       for(mi=1; mi<= wav[i]-1; mi++){
                   3556:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3557:          for (j=1;j<=nlstate+ndeath;j++){
                   3558:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3559:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3560:          }
                   3561:        for(d=0; d<=dh[mi][i]; d++){
                   3562:          newm=savm;
                   3563:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3564:          cov[2]=agexact;
                   3565:          if(nagesqr==1)
                   3566:            cov[3]= agexact*agexact;
                   3567:          for (kk=1; kk<=cptcovage;kk++) {
                   3568:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3569:          }
                   3570:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3571:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3572:          savm=oldm;
                   3573:          oldm=newm;
                   3574:        } /* end mult */
                   3575:       
                   3576:        s1=s[mw[mi][i]][i];
                   3577:        s2=s[mw[mi+1][i]][i];
                   3578:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3579:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3580:        ipmx +=1;
                   3581:        sw += weight[i];
                   3582:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3583:       } /* end of wave */
                   3584:     } /* end of individual */
                   3585:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3586:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3587:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3588:       for(mi=1; mi<= wav[i]-1; mi++){
                   3589:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3590:          for (j=1;j<=nlstate+ndeath;j++){
                   3591:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3592:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3593:          }
                   3594:        for(d=0; d<dh[mi][i]; d++){
                   3595:          newm=savm;
                   3596:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3597:          cov[2]=agexact;
                   3598:          if(nagesqr==1)
                   3599:            cov[3]= agexact*agexact;
                   3600:          for (kk=1; kk<=cptcovage;kk++) {
                   3601:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3602:          }
                   3603:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3604:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3605:          savm=oldm;
                   3606:          oldm=newm;
                   3607:        } /* end mult */
                   3608:       
                   3609:        s1=s[mw[mi][i]][i];
                   3610:        s2=s[mw[mi+1][i]][i];
                   3611:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3612:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3613:        ipmx +=1;
                   3614:        sw += weight[i];
                   3615:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3616:       } /* end of wave */
                   3617:     } /* end of individual */
                   3618:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3619:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3620:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3621:       for(mi=1; mi<= wav[i]-1; mi++){
                   3622:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3623:          for (j=1;j<=nlstate+ndeath;j++){
                   3624:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3625:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3626:          }
                   3627:        for(d=0; d<dh[mi][i]; d++){
                   3628:          newm=savm;
                   3629:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3630:          cov[2]=agexact;
                   3631:          if(nagesqr==1)
                   3632:            cov[3]= agexact*agexact;
                   3633:          for (kk=1; kk<=cptcovage;kk++) {
                   3634:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3635:          }
1.126     brouard  3636:        
1.226     brouard  3637:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3638:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3639:          savm=oldm;
                   3640:          oldm=newm;
                   3641:        } /* end mult */
                   3642:       
                   3643:        s1=s[mw[mi][i]][i];
                   3644:        s2=s[mw[mi+1][i]][i];
                   3645:        if( s2 > nlstate){ 
                   3646:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3647:        } else if  ( s2==-1 ) { /* alive */
                   3648:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3649:            survp += out[s1][j];
                   3650:          lli= log(survp);
                   3651:        }else{
                   3652:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3653:        }
                   3654:        ipmx +=1;
                   3655:        sw += weight[i];
                   3656:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3657: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3658:       } /* end of wave */
                   3659:     } /* end of individual */
                   3660:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3661:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3662:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3663:       for(mi=1; mi<= wav[i]-1; mi++){
                   3664:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3665:          for (j=1;j<=nlstate+ndeath;j++){
                   3666:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3667:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3668:          }
                   3669:        for(d=0; d<dh[mi][i]; d++){
                   3670:          newm=savm;
                   3671:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3672:          cov[2]=agexact;
                   3673:          if(nagesqr==1)
                   3674:            cov[3]= agexact*agexact;
                   3675:          for (kk=1; kk<=cptcovage;kk++) {
                   3676:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3677:          }
1.126     brouard  3678:        
1.226     brouard  3679:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3680:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3681:          savm=oldm;
                   3682:          oldm=newm;
                   3683:        } /* end mult */
                   3684:       
                   3685:        s1=s[mw[mi][i]][i];
                   3686:        s2=s[mw[mi+1][i]][i];
                   3687:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3688:        ipmx +=1;
                   3689:        sw += weight[i];
                   3690:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3691:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3692:       } /* end of wave */
                   3693:     } /* end of individual */
                   3694:   } /* End of if */
                   3695:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3696:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3697:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3698:   return -l;
1.126     brouard  3699: }
                   3700: 
                   3701: /*************** log-likelihood *************/
                   3702: double funcone( double *x)
                   3703: {
1.228     brouard  3704:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3705:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3706:   int ioffset=0;
1.131     brouard  3707:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3708:   double **out;
                   3709:   double lli; /* Individual log likelihood */
                   3710:   double llt;
                   3711:   int s1, s2;
1.228     brouard  3712:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3713: 
1.126     brouard  3714:   double bbh, survp;
1.187     brouard  3715:   double agexact;
1.214     brouard  3716:   double agebegin, ageend;
1.126     brouard  3717:   /*extern weight */
                   3718:   /* We are differentiating ll according to initial status */
                   3719:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3720:   /*for(i=1;i<imx;i++) 
                   3721:     printf(" %d\n",s[4][i]);
                   3722:   */
                   3723:   cov[1]=1.;
                   3724: 
                   3725:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3726:   ioffset=0;
                   3727:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3728:     /* ioffset=2+nagesqr+cptcovage; */
                   3729:     ioffset=2+nagesqr;
1.232     brouard  3730:     /* Fixed */
1.224     brouard  3731:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3732:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3733:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3734:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3735: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3736: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3737: /*    cov[2+6]=covar[2][i]; V2  */
                   3738: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3739: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3740: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3741: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3742: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3743: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3744:     }
1.232     brouard  3745:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3746:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3747:     /* } */
1.231     brouard  3748:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3749:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3750:     /* } */
1.225     brouard  3751:     
1.233     brouard  3752: 
                   3753:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3754:     /* Wave varying (but not age varying) */
                   3755:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3756:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3757:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3758:       }
1.232     brouard  3759:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3760:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3761:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3762:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3763:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3764:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3765:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3766:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3767:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3768:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3769:       /* } */
1.126     brouard  3770:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3771:        for (j=1;j<=nlstate+ndeath;j++){
                   3772:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3773:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3774:        }
1.214     brouard  3775:       
                   3776:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3777:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3778:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3779:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3780:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3781:          and mw[mi+1][i]. dh depends on stepm.*/
                   3782:        newm=savm;
1.247     brouard  3783:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3784:        cov[2]=agexact;
                   3785:        if(nagesqr==1)
                   3786:          cov[3]= agexact*agexact;
                   3787:        for (kk=1; kk<=cptcovage;kk++) {
                   3788:          if(!FixedV[Tvar[Tage[kk]]])
                   3789:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3790:          else
                   3791:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3792:        }
                   3793:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3794:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3795:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3796:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3797:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3798:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3799:        savm=oldm;
                   3800:        oldm=newm;
1.126     brouard  3801:       } /* end mult */
                   3802:       
                   3803:       s1=s[mw[mi][i]][i];
                   3804:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3805:       /* if(s2==-1){ */
1.268     brouard  3806:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3807:       /*       /\* exit(1); *\/ */
                   3808:       /* } */
1.126     brouard  3809:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3810:       /* bias is positive if real duration
                   3811:        * is higher than the multiple of stepm and negative otherwise.
                   3812:        */
                   3813:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3814:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3815:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3816:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3817:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3818:        lli= log(survp);
1.126     brouard  3819:       }else if (mle==1){
1.242     brouard  3820:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3821:       } else if(mle==2){
1.242     brouard  3822:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3823:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3824:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3825:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3826:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3827:       } else{  /* mle=0 back to 1 */
1.242     brouard  3828:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3829:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3830:       } /* End of if */
                   3831:       ipmx +=1;
                   3832:       sw += weight[i];
                   3833:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3834:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3835:       if(globpr){
1.246     brouard  3836:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3837:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3838:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3839:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3840:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3841:          llt +=ll[k]*gipmx/gsw;
                   3842:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3843:        }
                   3844:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3845:       }
1.232     brouard  3846:        } /* end of wave */
                   3847: } /* end of individual */
                   3848: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3849: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3850: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3851: if(globpr==0){ /* First time we count the contributions and weights */
                   3852:        gipmx=ipmx;
                   3853:        gsw=sw;
                   3854: }
                   3855: return -l;
1.126     brouard  3856: }
                   3857: 
                   3858: 
                   3859: /*************** function likelione ***********/
                   3860: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3861: {
                   3862:   /* This routine should help understanding what is done with 
                   3863:      the selection of individuals/waves and
                   3864:      to check the exact contribution to the likelihood.
                   3865:      Plotting could be done.
                   3866:    */
                   3867:   int k;
                   3868: 
                   3869:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3870:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3871:     strcat(fileresilk,fileresu);
1.126     brouard  3872:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3873:       printf("Problem with resultfile: %s\n", fileresilk);
                   3874:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3875:     }
1.214     brouard  3876:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3877:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3878:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3879:     for(k=1; k<=nlstate; k++) 
                   3880:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3881:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3882:   }
                   3883: 
                   3884:   *fretone=(*funcone)(p);
                   3885:   if(*globpri !=0){
                   3886:     fclose(ficresilk);
1.205     brouard  3887:     if (mle ==0)
                   3888:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3889:     else if(mle >=1)
                   3890:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3891:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3892:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3893:       
                   3894:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3895:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3896: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3897:     }
1.207     brouard  3898:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3899: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3900:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3901: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3902:     fflush(fichtm);
1.205     brouard  3903:   }
1.126     brouard  3904:   return;
                   3905: }
                   3906: 
                   3907: 
                   3908: /*********** Maximum Likelihood Estimation ***************/
                   3909: 
                   3910: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3911: {
1.165     brouard  3912:   int i,j, iter=0;
1.126     brouard  3913:   double **xi;
                   3914:   double fret;
                   3915:   double fretone; /* Only one call to likelihood */
                   3916:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3917: 
                   3918: #ifdef NLOPT
                   3919:   int creturn;
                   3920:   nlopt_opt opt;
                   3921:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3922:   double *lb;
                   3923:   double minf; /* the minimum objective value, upon return */
                   3924:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3925:   myfunc_data dinst, *d = &dinst;
                   3926: #endif
                   3927: 
                   3928: 
1.126     brouard  3929:   xi=matrix(1,npar,1,npar);
                   3930:   for (i=1;i<=npar;i++)
                   3931:     for (j=1;j<=npar;j++)
                   3932:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3933:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3934:   strcpy(filerespow,"POW_"); 
1.126     brouard  3935:   strcat(filerespow,fileres);
                   3936:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3937:     printf("Problem with resultfile: %s\n", filerespow);
                   3938:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3939:   }
                   3940:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3941:   for (i=1;i<=nlstate;i++)
                   3942:     for(j=1;j<=nlstate+ndeath;j++)
                   3943:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3944:   fprintf(ficrespow,"\n");
1.162     brouard  3945: #ifdef POWELL
1.126     brouard  3946:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3947: #endif
1.126     brouard  3948: 
1.162     brouard  3949: #ifdef NLOPT
                   3950: #ifdef NEWUOA
                   3951:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3952: #else
                   3953:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3954: #endif
                   3955:   lb=vector(0,npar-1);
                   3956:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3957:   nlopt_set_lower_bounds(opt, lb);
                   3958:   nlopt_set_initial_step1(opt, 0.1);
                   3959:   
                   3960:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3961:   d->function = func;
                   3962:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3963:   nlopt_set_min_objective(opt, myfunc, d);
                   3964:   nlopt_set_xtol_rel(opt, ftol);
                   3965:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3966:     printf("nlopt failed! %d\n",creturn); 
                   3967:   }
                   3968:   else {
                   3969:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3970:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3971:     iter=1; /* not equal */
                   3972:   }
                   3973:   nlopt_destroy(opt);
                   3974: #endif
1.126     brouard  3975:   free_matrix(xi,1,npar,1,npar);
                   3976:   fclose(ficrespow);
1.203     brouard  3977:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3978:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3979:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3980: 
                   3981: }
                   3982: 
                   3983: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3984: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3985: {
                   3986:   double  **a,**y,*x,pd;
1.203     brouard  3987:   /* double **hess; */
1.164     brouard  3988:   int i, j;
1.126     brouard  3989:   int *indx;
                   3990: 
                   3991:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3992:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3993:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3994:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3995:   double gompertz(double p[]);
1.203     brouard  3996:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3997: 
                   3998:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3999:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4000:   for (i=1;i<=npar;i++){
1.203     brouard  4001:     printf("%d-",i);fflush(stdout);
                   4002:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4003:    
                   4004:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4005:     
                   4006:     /*  printf(" %f ",p[i]);
                   4007:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4008:   }
                   4009:   
                   4010:   for (i=1;i<=npar;i++) {
                   4011:     for (j=1;j<=npar;j++)  {
                   4012:       if (j>i) { 
1.203     brouard  4013:        printf(".%d-%d",i,j);fflush(stdout);
                   4014:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4015:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4016:        
                   4017:        hess[j][i]=hess[i][j];    
                   4018:        /*printf(" %lf ",hess[i][j]);*/
                   4019:       }
                   4020:     }
                   4021:   }
                   4022:   printf("\n");
                   4023:   fprintf(ficlog,"\n");
                   4024: 
                   4025:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4026:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4027:   
                   4028:   a=matrix(1,npar,1,npar);
                   4029:   y=matrix(1,npar,1,npar);
                   4030:   x=vector(1,npar);
                   4031:   indx=ivector(1,npar);
                   4032:   for (i=1;i<=npar;i++)
                   4033:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4034:   ludcmp(a,npar,indx,&pd);
                   4035: 
                   4036:   for (j=1;j<=npar;j++) {
                   4037:     for (i=1;i<=npar;i++) x[i]=0;
                   4038:     x[j]=1;
                   4039:     lubksb(a,npar,indx,x);
                   4040:     for (i=1;i<=npar;i++){ 
                   4041:       matcov[i][j]=x[i];
                   4042:     }
                   4043:   }
                   4044: 
                   4045:   printf("\n#Hessian matrix#\n");
                   4046:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4047:   for (i=1;i<=npar;i++) { 
                   4048:     for (j=1;j<=npar;j++) { 
1.203     brouard  4049:       printf("%.6e ",hess[i][j]);
                   4050:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4051:     }
                   4052:     printf("\n");
                   4053:     fprintf(ficlog,"\n");
                   4054:   }
                   4055: 
1.203     brouard  4056:   /* printf("\n#Covariance matrix#\n"); */
                   4057:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4058:   /* for (i=1;i<=npar;i++) {  */
                   4059:   /*   for (j=1;j<=npar;j++) {  */
                   4060:   /*     printf("%.6e ",matcov[i][j]); */
                   4061:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4062:   /*   } */
                   4063:   /*   printf("\n"); */
                   4064:   /*   fprintf(ficlog,"\n"); */
                   4065:   /* } */
                   4066: 
1.126     brouard  4067:   /* Recompute Inverse */
1.203     brouard  4068:   /* for (i=1;i<=npar;i++) */
                   4069:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4070:   /* ludcmp(a,npar,indx,&pd); */
                   4071: 
                   4072:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4073: 
                   4074:   /* for (j=1;j<=npar;j++) { */
                   4075:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4076:   /*   x[j]=1; */
                   4077:   /*   lubksb(a,npar,indx,x); */
                   4078:   /*   for (i=1;i<=npar;i++){  */
                   4079:   /*     y[i][j]=x[i]; */
                   4080:   /*     printf("%.3e ",y[i][j]); */
                   4081:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4082:   /*   } */
                   4083:   /*   printf("\n"); */
                   4084:   /*   fprintf(ficlog,"\n"); */
                   4085:   /* } */
                   4086: 
                   4087:   /* Verifying the inverse matrix */
                   4088: #ifdef DEBUGHESS
                   4089:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4090: 
1.203     brouard  4091:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4092:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4093: 
                   4094:   for (j=1;j<=npar;j++) {
                   4095:     for (i=1;i<=npar;i++){ 
1.203     brouard  4096:       printf("%.2f ",y[i][j]);
                   4097:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4098:     }
                   4099:     printf("\n");
                   4100:     fprintf(ficlog,"\n");
                   4101:   }
1.203     brouard  4102: #endif
1.126     brouard  4103: 
                   4104:   free_matrix(a,1,npar,1,npar);
                   4105:   free_matrix(y,1,npar,1,npar);
                   4106:   free_vector(x,1,npar);
                   4107:   free_ivector(indx,1,npar);
1.203     brouard  4108:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4109: 
                   4110: 
                   4111: }
                   4112: 
                   4113: /*************** hessian matrix ****************/
                   4114: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4115: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4116:   int i;
                   4117:   int l=1, lmax=20;
1.203     brouard  4118:   double k1,k2, res, fx;
1.132     brouard  4119:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4120:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4121:   int k=0,kmax=10;
                   4122:   double l1;
                   4123: 
                   4124:   fx=func(x);
                   4125:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4126:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4127:     l1=pow(10,l);
                   4128:     delts=delt;
                   4129:     for(k=1 ; k <kmax; k=k+1){
                   4130:       delt = delta*(l1*k);
                   4131:       p2[theta]=x[theta] +delt;
1.145     brouard  4132:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4133:       p2[theta]=x[theta]-delt;
                   4134:       k2=func(p2)-fx;
                   4135:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4136:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4137:       
1.203     brouard  4138: #ifdef DEBUGHESSII
1.126     brouard  4139:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4140:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4141: #endif
                   4142:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4143:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4144:        k=kmax;
                   4145:       }
                   4146:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4147:        k=kmax; l=lmax*10;
1.126     brouard  4148:       }
                   4149:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4150:        delts=delt;
                   4151:       }
1.203     brouard  4152:     } /* End loop k */
1.126     brouard  4153:   }
                   4154:   delti[theta]=delts;
                   4155:   return res; 
                   4156:   
                   4157: }
                   4158: 
1.203     brouard  4159: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4160: {
                   4161:   int i;
1.164     brouard  4162:   int l=1, lmax=20;
1.126     brouard  4163:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4164:   double p2[MAXPARM+1];
1.203     brouard  4165:   int k, kmax=1;
                   4166:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4167: 
                   4168:   int firstime=0;
1.203     brouard  4169:   
1.126     brouard  4170:   fx=func(x);
1.203     brouard  4171:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4172:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4173:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4174:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4175:     k1=func(p2)-fx;
                   4176:   
1.203     brouard  4177:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4178:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4179:     k2=func(p2)-fx;
                   4180:   
1.203     brouard  4181:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4182:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4183:     k3=func(p2)-fx;
                   4184:   
1.203     brouard  4185:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4186:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4187:     k4=func(p2)-fx;
1.203     brouard  4188:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4189:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4190:       firstime=1;
1.203     brouard  4191:       kmax=kmax+10;
1.208     brouard  4192:     }
                   4193:     if(kmax >=10 || firstime ==1){
1.246     brouard  4194:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4195:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4196:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4197:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4198:     }
                   4199: #ifdef DEBUGHESSIJ
                   4200:     v1=hess[thetai][thetai];
                   4201:     v2=hess[thetaj][thetaj];
                   4202:     cv12=res;
                   4203:     /* Computing eigen value of Hessian matrix */
                   4204:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4205:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4206:     if ((lc2 <0) || (lc1 <0) ){
                   4207:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4208:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4209:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4210:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4211:     }
1.126     brouard  4212: #endif
                   4213:   }
                   4214:   return res;
                   4215: }
                   4216: 
1.203     brouard  4217:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4218: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4219: /* { */
                   4220: /*   int i; */
                   4221: /*   int l=1, lmax=20; */
                   4222: /*   double k1,k2,k3,k4,res,fx; */
                   4223: /*   double p2[MAXPARM+1]; */
                   4224: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4225: /*   int k=0,kmax=10; */
                   4226: /*   double l1; */
                   4227:   
                   4228: /*   fx=func(x); */
                   4229: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4230: /*     l1=pow(10,l); */
                   4231: /*     delts=delt; */
                   4232: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4233: /*       delt = delti*(l1*k); */
                   4234: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4235: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4236: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4237: /*       k1=func(p2)-fx; */
                   4238:       
                   4239: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4240: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4241: /*       k2=func(p2)-fx; */
                   4242:       
                   4243: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4244: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4245: /*       k3=func(p2)-fx; */
                   4246:       
                   4247: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4248: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4249: /*       k4=func(p2)-fx; */
                   4250: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4251: /* #ifdef DEBUGHESSIJ */
                   4252: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4253: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4254: /* #endif */
                   4255: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4256: /*     k=kmax; */
                   4257: /*       } */
                   4258: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4259: /*     k=kmax; l=lmax*10; */
                   4260: /*       } */
                   4261: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4262: /*     delts=delt; */
                   4263: /*       } */
                   4264: /*     } /\* End loop k *\/ */
                   4265: /*   } */
                   4266: /*   delti[theta]=delts; */
                   4267: /*   return res;  */
                   4268: /* } */
                   4269: 
                   4270: 
1.126     brouard  4271: /************** Inverse of matrix **************/
                   4272: void ludcmp(double **a, int n, int *indx, double *d) 
                   4273: { 
                   4274:   int i,imax,j,k; 
                   4275:   double big,dum,sum,temp; 
                   4276:   double *vv; 
                   4277:  
                   4278:   vv=vector(1,n); 
                   4279:   *d=1.0; 
                   4280:   for (i=1;i<=n;i++) { 
                   4281:     big=0.0; 
                   4282:     for (j=1;j<=n;j++) 
                   4283:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4284:     if (big == 0.0){
                   4285:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4286:       for (j=1;j<=n;j++) {
                   4287:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4288:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4289:       }
                   4290:       fflush(ficlog);
                   4291:       fclose(ficlog);
                   4292:       nrerror("Singular matrix in routine ludcmp"); 
                   4293:     }
1.126     brouard  4294:     vv[i]=1.0/big; 
                   4295:   } 
                   4296:   for (j=1;j<=n;j++) { 
                   4297:     for (i=1;i<j;i++) { 
                   4298:       sum=a[i][j]; 
                   4299:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4300:       a[i][j]=sum; 
                   4301:     } 
                   4302:     big=0.0; 
                   4303:     for (i=j;i<=n;i++) { 
                   4304:       sum=a[i][j]; 
                   4305:       for (k=1;k<j;k++) 
                   4306:        sum -= a[i][k]*a[k][j]; 
                   4307:       a[i][j]=sum; 
                   4308:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4309:        big=dum; 
                   4310:        imax=i; 
                   4311:       } 
                   4312:     } 
                   4313:     if (j != imax) { 
                   4314:       for (k=1;k<=n;k++) { 
                   4315:        dum=a[imax][k]; 
                   4316:        a[imax][k]=a[j][k]; 
                   4317:        a[j][k]=dum; 
                   4318:       } 
                   4319:       *d = -(*d); 
                   4320:       vv[imax]=vv[j]; 
                   4321:     } 
                   4322:     indx[j]=imax; 
                   4323:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4324:     if (j != n) { 
                   4325:       dum=1.0/(a[j][j]); 
                   4326:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4327:     } 
                   4328:   } 
                   4329:   free_vector(vv,1,n);  /* Doesn't work */
                   4330: ;
                   4331: } 
                   4332: 
                   4333: void lubksb(double **a, int n, int *indx, double b[]) 
                   4334: { 
                   4335:   int i,ii=0,ip,j; 
                   4336:   double sum; 
                   4337:  
                   4338:   for (i=1;i<=n;i++) { 
                   4339:     ip=indx[i]; 
                   4340:     sum=b[ip]; 
                   4341:     b[ip]=b[i]; 
                   4342:     if (ii) 
                   4343:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4344:     else if (sum) ii=i; 
                   4345:     b[i]=sum; 
                   4346:   } 
                   4347:   for (i=n;i>=1;i--) { 
                   4348:     sum=b[i]; 
                   4349:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4350:     b[i]=sum/a[i][i]; 
                   4351:   } 
                   4352: } 
                   4353: 
                   4354: void pstamp(FILE *fichier)
                   4355: {
1.196     brouard  4356:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4357: }
                   4358: 
1.253     brouard  4359: 
                   4360: 
1.126     brouard  4361: /************ Frequencies ********************/
1.251     brouard  4362: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4363:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4364:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4365: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4366:   
1.265     brouard  4367:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4368:   int iind=0, iage=0;
                   4369:   int mi; /* Effective wave */
                   4370:   int first;
                   4371:   double ***freq; /* Frequencies */
1.268     brouard  4372:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4373:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284   ! brouard  4374:   double *meanq, *stdq, *idq;
1.226     brouard  4375:   double **meanqt;
                   4376:   double *pp, **prop, *posprop, *pospropt;
                   4377:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4378:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4379:   double agebegin, ageend;
                   4380:     
                   4381:   pp=vector(1,nlstate);
1.251     brouard  4382:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4383:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4384:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4385:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4386:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284   ! brouard  4387:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4388:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4389:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4390:   strcpy(fileresp,"P_");
                   4391:   strcat(fileresp,fileresu);
                   4392:   /*strcat(fileresphtm,fileresu);*/
                   4393:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4394:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4395:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4396:     exit(0);
                   4397:   }
1.240     brouard  4398:   
1.226     brouard  4399:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4400:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4401:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4402:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4403:     fflush(ficlog);
                   4404:     exit(70); 
                   4405:   }
                   4406:   else{
                   4407:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4408: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4409: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4410:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4411:   }
1.237     brouard  4412:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4413:   
1.226     brouard  4414:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4415:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4416:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4417:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4418:     fflush(ficlog);
                   4419:     exit(70); 
1.240     brouard  4420:   } else{
1.226     brouard  4421:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4422: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4423: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4424:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4425:   }
1.240     brouard  4426:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4427:   
1.253     brouard  4428:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4429:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4430:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4431:   j1=0;
1.126     brouard  4432:   
1.227     brouard  4433:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4434:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4435:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4436:   
                   4437:   
1.226     brouard  4438:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4439:      reference=low_education V1=0,V2=0
                   4440:      med_educ                V1=1 V2=0, 
                   4441:      high_educ               V1=0 V2=1
                   4442:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4443:   */
1.249     brouard  4444:   dateintsum=0;
                   4445:   k2cpt=0;
                   4446: 
1.253     brouard  4447:   if(cptcoveff == 0 )
1.265     brouard  4448:     nl=1;  /* Constant and age model only */
1.253     brouard  4449:   else
                   4450:     nl=2;
1.265     brouard  4451: 
                   4452:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4453:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4454:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4455:    *     freq[s1][s2][iage] =0.
                   4456:    *     Loop on iind
                   4457:    *       ++freq[s1][s2][iage] weighted
                   4458:    *     end iind
                   4459:    *     if covariate and j!0
                   4460:    *       headers Variable on one line
                   4461:    *     endif cov j!=0
                   4462:    *     header of frequency table by age
                   4463:    *     Loop on age
                   4464:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4465:    *       pos+=freq[s1][s2][iage] weighted
                   4466:    *       Loop on s1 initial state
                   4467:    *         fprintf(ficresp
                   4468:    *       end s1
                   4469:    *     end age
                   4470:    *     if j!=0 computes starting values
                   4471:    *     end compute starting values
                   4472:    *   end j1
                   4473:    * end nl 
                   4474:    */
1.253     brouard  4475:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4476:     if(nj==1)
                   4477:       j=0;  /* First pass for the constant */
1.265     brouard  4478:     else{
1.253     brouard  4479:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4480:     }
1.251     brouard  4481:     first=1;
1.265     brouard  4482:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4483:       posproptt=0.;
                   4484:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4485:        scanf("%d", i);*/
                   4486:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4487:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4488:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4489:            freq[i][s2][m]=0;
1.251     brouard  4490:       
                   4491:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4492:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4493:          prop[i][m]=0;
                   4494:        posprop[i]=0;
                   4495:        pospropt[i]=0;
                   4496:       }
1.283     brouard  4497:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284   ! brouard  4498:         idq[z1]=0.;
        !          4499:         meanq[z1]=0.;
        !          4500:         stdq[z1]=0.;
1.283     brouard  4501:       }
                   4502:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4503:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4504:       /*         meanqt[m][z1]=0.; */
                   4505:       /*       } */
                   4506:       /* }       */
1.251     brouard  4507:       /* dateintsum=0; */
                   4508:       /* k2cpt=0; */
                   4509:       
1.265     brouard  4510:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4511:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4512:        bool=1;
                   4513:        if(j !=0){
                   4514:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4515:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4516:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4517:                /* if(Tvaraff[z1] ==-20){ */
                   4518:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4519:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4520:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4521:                /* }else  */
                   4522:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4523:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4524:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4525:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4526:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4527:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4528:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4529:                } /* Onlyf fixed */
                   4530:              } /* end z1 */
                   4531:            } /* cptcovn > 0 */
                   4532:          } /* end any */
                   4533:        }/* end j==0 */
1.265     brouard  4534:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4535:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284   ! brouard  4536:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4537:            m=mw[mi][iind];
                   4538:            if(j!=0){
                   4539:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4540:                for (z1=1; z1<=cptcoveff; z1++) {
                   4541:                  if( Fixed[Tmodelind[z1]]==1){
                   4542:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4543:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4544:                                                                                      value is -1, we don't select. It differs from the 
                   4545:                                                                                      constant and age model which counts them. */
                   4546:                      bool=0; /* not selected */
                   4547:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4548:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4549:                      bool=0;
                   4550:                    }
                   4551:                  }
                   4552:                }
                   4553:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4554:            } /* end j==0 */
                   4555:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284   ! brouard  4556:            if(bool==1){ /*Selected */
1.251     brouard  4557:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4558:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4559:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4560:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4561:              if(m >=firstpass && m <=lastpass){
                   4562:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4563:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4564:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4565:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4566:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4567:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4568:                if (m<lastpass) {
                   4569:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4570:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4571:                  if(s[m][iind]==-1)
                   4572:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4573:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284   ! brouard  4574:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
        !          4575:                    idq[z1]=idq[z1]+weight[iind];
        !          4576:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
        !          4577:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
        !          4578:                  }
1.251     brouard  4579:                  /* if((int)agev[m][iind] == 55) */
                   4580:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4581:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4582:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4583:                }
1.251     brouard  4584:              } /* end if between passes */  
                   4585:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4586:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4587:                k2cpt++;
                   4588:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4589:              }
1.251     brouard  4590:            }else{
                   4591:              bool=1;
                   4592:            }/* end bool 2 */
                   4593:          } /* end m */
1.284   ! brouard  4594:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
        !          4595:          /*   idq[z1]=idq[z1]+weight[iind]; */
        !          4596:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
        !          4597:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
        !          4598:          /* } */
1.251     brouard  4599:        } /* end bool */
                   4600:       } /* end iind = 1 to imx */
                   4601:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4602:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4603:       
                   4604:       
                   4605:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4606:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4607:         pstamp(ficresp);
1.251     brouard  4608:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4609:         pstamp(ficresp);
1.251     brouard  4610:        printf( "\n#********** Variable "); 
                   4611:        fprintf(ficresp, "\n#********** Variable "); 
                   4612:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4613:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4614:        fprintf(ficlog, "\n#********** Variable "); 
                   4615:        for (z1=1; z1<=cptcoveff; z1++){
                   4616:          if(!FixedV[Tvaraff[z1]]){
                   4617:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4618:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4619:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4620:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4621:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4622:          }else{
1.251     brouard  4623:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4624:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4625:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4626:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4627:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4628:          }
                   4629:        }
                   4630:        printf( "**********\n#");
                   4631:        fprintf(ficresp, "**********\n#");
                   4632:        fprintf(ficresphtm, "**********</h3>\n");
                   4633:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4634:        fprintf(ficlog, "**********\n");
                   4635:       }
1.284   ! brouard  4636:       /*
        !          4637:        Printing means of quantitative variables if any
        !          4638:       */
        !          4639:       for (z1=1; z1<= nqfveff; z1++) {
        !          4640:        fprintf(ficlog,"Mean of quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
        !          4641:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
        !          4642:        if(weightopt==1){
        !          4643:          printf(" Weighted mean and standard deviation of");
        !          4644:          fprintf(ficlog," Weighted mean and standard deviation of");
        !          4645:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
        !          4646:        }
        !          4647:        printf(" quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
        !          4648:        fprintf(ficlog," quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
        !          4649:        fprintf(ficresphtmfr," quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
        !          4650:       }
        !          4651:       /* for (z1=1; z1<= nqtveff; z1++) { */
        !          4652:       /*       for(m=1;m<=lastpass;m++){ */
        !          4653:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
        !          4654:       /*   } */
        !          4655:       /* } */
1.283     brouard  4656: 
1.251     brouard  4657:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4658:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4659:         fprintf(ficresp, " Age");
                   4660:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4661:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4662:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4663:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4664:       }
1.265     brouard  4665:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4666:       fprintf(ficresphtm, "\n");
                   4667:       
                   4668:       /* Header of frequency table by age */
                   4669:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4670:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4671:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4672:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4673:          if(s2!=0 && m!=0)
                   4674:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4675:        }
1.226     brouard  4676:       }
1.251     brouard  4677:       fprintf(ficresphtmfr, "\n");
                   4678:     
                   4679:       /* For each age */
                   4680:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4681:        fprintf(ficresphtm,"<tr>");
                   4682:        if(iage==iagemax+1){
                   4683:          fprintf(ficlog,"1");
                   4684:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4685:        }else if(iage==iagemax+2){
                   4686:          fprintf(ficlog,"0");
                   4687:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4688:        }else if(iage==iagemax+3){
                   4689:          fprintf(ficlog,"Total");
                   4690:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4691:        }else{
1.240     brouard  4692:          if(first==1){
1.251     brouard  4693:            first=0;
                   4694:            printf("See log file for details...\n");
                   4695:          }
                   4696:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4697:          fprintf(ficlog,"Age %d", iage);
                   4698:        }
1.265     brouard  4699:        for(s1=1; s1 <=nlstate ; s1++){
                   4700:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4701:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4702:        }
1.265     brouard  4703:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4704:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4705:            pos += freq[s1][m][iage];
                   4706:          if(pp[s1]>=1.e-10){
1.251     brouard  4707:            if(first==1){
1.265     brouard  4708:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4709:            }
1.265     brouard  4710:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4711:          }else{
                   4712:            if(first==1)
1.265     brouard  4713:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4714:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4715:          }
                   4716:        }
                   4717:       
1.265     brouard  4718:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4719:          /* posprop[s1]=0; */
                   4720:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4721:            pp[s1] += freq[s1][m][iage];
                   4722:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4723:       
                   4724:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4725:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4726:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4727:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4728:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4729:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4730:        }
                   4731:        
                   4732:        /* Writing ficresp */
                   4733:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4734:           if( iage <= iagemax){
                   4735:            fprintf(ficresp," %d",iage);
                   4736:           }
                   4737:         }else if( nj==2){
                   4738:           if( iage <= iagemax){
                   4739:            fprintf(ficresp," %d",iage);
                   4740:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4741:           }
1.240     brouard  4742:        }
1.265     brouard  4743:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4744:          if(pos>=1.e-5){
1.251     brouard  4745:            if(first==1)
1.265     brouard  4746:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4747:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4748:          }else{
                   4749:            if(first==1)
1.265     brouard  4750:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4751:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4752:          }
                   4753:          if( iage <= iagemax){
                   4754:            if(pos>=1.e-5){
1.265     brouard  4755:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4756:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4757:               }else if( nj==2){
                   4758:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4759:               }
                   4760:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4761:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4762:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4763:            } else{
                   4764:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4765:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4766:            }
1.240     brouard  4767:          }
1.265     brouard  4768:          pospropt[s1] +=posprop[s1];
                   4769:        } /* end loop s1 */
1.251     brouard  4770:        /* pospropt=0.; */
1.265     brouard  4771:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4772:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4773:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4774:              if(first==1){
1.265     brouard  4775:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4776:              }
1.265     brouard  4777:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4778:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4779:            }
1.265     brouard  4780:            if(s1!=0 && m!=0)
                   4781:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4782:          }
1.265     brouard  4783:        } /* end loop s1 */
1.251     brouard  4784:        posproptt=0.; 
1.265     brouard  4785:        for(s1=1; s1 <=nlstate; s1++){
                   4786:          posproptt += pospropt[s1];
1.251     brouard  4787:        }
                   4788:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4789:        fprintf(ficresphtm,"</tr>\n");
                   4790:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4791:          if(iage <= iagemax)
                   4792:            fprintf(ficresp,"\n");
1.240     brouard  4793:        }
1.251     brouard  4794:        if(first==1)
                   4795:          printf("Others in log...\n");
                   4796:        fprintf(ficlog,"\n");
                   4797:       } /* end loop age iage */
1.265     brouard  4798:       
1.251     brouard  4799:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4800:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4801:        if(posproptt < 1.e-5){
1.265     brouard  4802:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4803:        }else{
1.265     brouard  4804:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4805:        }
1.226     brouard  4806:       }
1.251     brouard  4807:       fprintf(ficresphtm,"</tr>\n");
                   4808:       fprintf(ficresphtm,"</table>\n");
                   4809:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4810:       if(posproptt < 1.e-5){
1.251     brouard  4811:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4812:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4813:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4814:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4815:        invalidvarcomb[j1]=1;
1.226     brouard  4816:       }else{
1.251     brouard  4817:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4818:        invalidvarcomb[j1]=0;
1.226     brouard  4819:       }
1.251     brouard  4820:       fprintf(ficresphtmfr,"</table>\n");
                   4821:       fprintf(ficlog,"\n");
                   4822:       if(j!=0){
                   4823:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4824:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4825:          for(k=1; k <=(nlstate+ndeath); k++){
                   4826:            if (k != i) {
1.265     brouard  4827:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4828:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4829:                  if(j1==1){ /* All dummy covariates to zero */
                   4830:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4831:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4832:                    printf("%d%d ",i,k);
                   4833:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4834:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4835:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4836:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4837:                  }
1.253     brouard  4838:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4839:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4840:                    x[iage]= (double)iage;
                   4841:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4842:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4843:                  }
1.268     brouard  4844:                  /* Some are not finite, but linreg will ignore these ages */
                   4845:                  no=0;
1.253     brouard  4846:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4847:                  pstart[s1]=b;
                   4848:                  pstart[s1-1]=a;
1.252     brouard  4849:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4850:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4851:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4852:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4853:                  printf("%d%d ",i,k);
                   4854:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4855:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4856:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4857:                  ;
                   4858:                }
                   4859:                /* printf("%12.7f )", param[i][jj][k]); */
                   4860:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4861:                s1++; 
1.251     brouard  4862:              } /* end jj */
                   4863:            } /* end k!= i */
                   4864:          } /* end k */
1.265     brouard  4865:        } /* end i, s1 */
1.251     brouard  4866:       } /* end j !=0 */
                   4867:     } /* end selected combination of covariate j1 */
                   4868:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4869:       printf("#Freqsummary: Starting values for the constants:\n");
                   4870:       fprintf(ficlog,"\n");
1.265     brouard  4871:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4872:        for(k=1; k <=(nlstate+ndeath); k++){
                   4873:          if (k != i) {
                   4874:            printf("%d%d ",i,k);
                   4875:            fprintf(ficlog,"%d%d ",i,k);
                   4876:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4877:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4878:              if(jj==1){ /* Age has to be done */
1.265     brouard  4879:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4880:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4881:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4882:              }
                   4883:              /* printf("%12.7f )", param[i][jj][k]); */
                   4884:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4885:              s1++; 
1.250     brouard  4886:            }
1.251     brouard  4887:            printf("\n");
                   4888:            fprintf(ficlog,"\n");
1.250     brouard  4889:          }
                   4890:        }
1.284   ! brouard  4891:       } /* end of state i */
1.251     brouard  4892:       printf("#Freqsummary\n");
                   4893:       fprintf(ficlog,"\n");
1.265     brouard  4894:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4895:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4896:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4897:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4898:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4899:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4900:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4901:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4902:          /* } */
                   4903:        }
1.265     brouard  4904:       } /* end loop s1 */
1.251     brouard  4905:       
                   4906:       printf("\n");
                   4907:       fprintf(ficlog,"\n");
                   4908:     } /* end j=0 */
1.249     brouard  4909:   } /* end j */
1.252     brouard  4910: 
1.253     brouard  4911:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4912:     for(i=1, jk=1; i <=nlstate; i++){
                   4913:       for(j=1; j <=nlstate+ndeath; j++){
                   4914:        if(j!=i){
                   4915:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4916:          printf("%1d%1d",i,j);
                   4917:          fprintf(ficparo,"%1d%1d",i,j);
                   4918:          for(k=1; k<=ncovmodel;k++){
                   4919:            /*    printf(" %lf",param[i][j][k]); */
                   4920:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4921:            p[jk]=pstart[jk];
                   4922:            printf(" %f ",pstart[jk]);
                   4923:            fprintf(ficparo," %f ",pstart[jk]);
                   4924:            jk++;
                   4925:          }
                   4926:          printf("\n");
                   4927:          fprintf(ficparo,"\n");
                   4928:        }
                   4929:       }
                   4930:     }
                   4931:   } /* end mle=-2 */
1.226     brouard  4932:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4933:   
1.226     brouard  4934:   fclose(ficresp);
                   4935:   fclose(ficresphtm);
                   4936:   fclose(ficresphtmfr);
1.283     brouard  4937:   free_vector(idq,1,nqfveff);
1.226     brouard  4938:   free_vector(meanq,1,nqfveff);
1.284   ! brouard  4939:   free_vector(stdq,1,nqfveff);
1.226     brouard  4940:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4941:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4942:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4943:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4944:   free_vector(pospropt,1,nlstate);
                   4945:   free_vector(posprop,1,nlstate);
1.251     brouard  4946:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4947:   free_vector(pp,1,nlstate);
                   4948:   /* End of freqsummary */
                   4949: }
1.126     brouard  4950: 
1.268     brouard  4951: /* Simple linear regression */
                   4952: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4953: 
                   4954:   /* y=a+bx regression */
                   4955:   double   sumx = 0.0;                        /* sum of x                      */
                   4956:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4957:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4958:   double   sumy = 0.0;                        /* sum of y                      */
                   4959:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4960:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4961:   double yhat;
                   4962:   
                   4963:   double denom=0;
                   4964:   int i;
                   4965:   int ne=*no;
                   4966:   
                   4967:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4968:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4969:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4970:       continue;
                   4971:     }
                   4972:     ne=ne+1;
                   4973:     sumx  += x[i];       
                   4974:     sumx2 += x[i]*x[i];  
                   4975:     sumxy += x[i] * y[i];
                   4976:     sumy  += y[i];      
                   4977:     sumy2 += y[i]*y[i]; 
                   4978:     denom = (ne * sumx2 - sumx*sumx);
                   4979:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4980:   } 
                   4981:   
                   4982:   denom = (ne * sumx2 - sumx*sumx);
                   4983:   if (denom == 0) {
                   4984:     // vertical, slope m is infinity
                   4985:     *b = INFINITY;
                   4986:     *a = 0;
                   4987:     if (r) *r = 0;
                   4988:     return 1;
                   4989:   }
                   4990:   
                   4991:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4992:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4993:   if (r!=NULL) {
                   4994:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4995:       sqrt((sumx2 - sumx*sumx/ne) *
                   4996:           (sumy2 - sumy*sumy/ne));
                   4997:   }
                   4998:   *no=ne;
                   4999:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5000:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5001:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5002:       continue;
                   5003:     }
                   5004:     ne=ne+1;
                   5005:     yhat = y[i] - *a -*b* x[i];
                   5006:     sume2  += yhat * yhat ;       
                   5007:     
                   5008:     denom = (ne * sumx2 - sumx*sumx);
                   5009:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5010:   } 
                   5011:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5012:   *sa= *sb * sqrt(sumx2/ne);
                   5013:   
                   5014:   return 0; 
                   5015: }
                   5016: 
1.126     brouard  5017: /************ Prevalence ********************/
1.227     brouard  5018: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5019: {  
                   5020:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5021:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5022:      We still use firstpass and lastpass as another selection.
                   5023:   */
1.126     brouard  5024:  
1.227     brouard  5025:   int i, m, jk, j1, bool, z1,j, iv;
                   5026:   int mi; /* Effective wave */
                   5027:   int iage;
                   5028:   double agebegin, ageend;
                   5029: 
                   5030:   double **prop;
                   5031:   double posprop; 
                   5032:   double  y2; /* in fractional years */
                   5033:   int iagemin, iagemax;
                   5034:   int first; /** to stop verbosity which is redirected to log file */
                   5035: 
                   5036:   iagemin= (int) agemin;
                   5037:   iagemax= (int) agemax;
                   5038:   /*pp=vector(1,nlstate);*/
1.251     brouard  5039:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5040:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5041:   j1=0;
1.222     brouard  5042:   
1.227     brouard  5043:   /*j=cptcoveff;*/
                   5044:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5045:   
1.227     brouard  5046:   first=1;
                   5047:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5048:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5049:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5050:        prop[i][iage]=0.0;
                   5051:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5052:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5053:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5054:     
                   5055:     for (i=1; i<=imx; i++) { /* Each individual */
                   5056:       bool=1;
                   5057:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5058:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5059:        m=mw[mi][i];
                   5060:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5061:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5062:        for (z1=1; z1<=cptcoveff; z1++){
                   5063:          if( Fixed[Tmodelind[z1]]==1){
                   5064:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5065:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5066:              bool=0;
                   5067:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5068:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5069:              bool=0;
                   5070:            }
                   5071:        }
                   5072:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5073:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5074:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5075:          if(m >=firstpass && m <=lastpass){
                   5076:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5077:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5078:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5079:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5080:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5081:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5082:                exit(1);
                   5083:              }
                   5084:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5085:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5086:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5087:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5088:              } /* end valid statuses */ 
                   5089:            } /* end selection of dates */
                   5090:          } /* end selection of waves */
                   5091:        } /* end bool */
                   5092:       } /* end wave */
                   5093:     } /* end individual */
                   5094:     for(i=iagemin; i <= iagemax+3; i++){  
                   5095:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5096:        posprop += prop[jk][i]; 
                   5097:       } 
                   5098:       
                   5099:       for(jk=1; jk <=nlstate ; jk++){      
                   5100:        if( i <=  iagemax){ 
                   5101:          if(posprop>=1.e-5){ 
                   5102:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5103:          } else{
                   5104:            if(first==1){
                   5105:              first=0;
1.266     brouard  5106:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5107:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5108:            }else{
                   5109:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5110:            }
                   5111:          }
                   5112:        } 
                   5113:       }/* end jk */ 
                   5114:     }/* end i */ 
1.222     brouard  5115:      /*} *//* end i1 */
1.227     brouard  5116:   } /* end j1 */
1.222     brouard  5117:   
1.227     brouard  5118:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5119:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5120:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5121: }  /* End of prevalence */
1.126     brouard  5122: 
                   5123: /************* Waves Concatenation ***************/
                   5124: 
                   5125: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5126: {
                   5127:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5128:      Death is a valid wave (if date is known).
                   5129:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5130:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5131:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5132:   */
1.126     brouard  5133: 
1.224     brouard  5134:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5135:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5136:      double sum=0., jmean=0.;*/
1.224     brouard  5137:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5138:   int j, k=0,jk, ju, jl;
                   5139:   double sum=0.;
                   5140:   first=0;
1.214     brouard  5141:   firstwo=0;
1.217     brouard  5142:   firsthree=0;
1.218     brouard  5143:   firstfour=0;
1.164     brouard  5144:   jmin=100000;
1.126     brouard  5145:   jmax=-1;
                   5146:   jmean=0.;
1.224     brouard  5147: 
                   5148: /* Treating live states */
1.214     brouard  5149:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5150:     mi=0;  /* First valid wave */
1.227     brouard  5151:     mli=0; /* Last valid wave */
1.126     brouard  5152:     m=firstpass;
1.214     brouard  5153:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5154:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5155:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5156:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5157:        mw[++mi][i]=m;
                   5158:        mli=m;
1.224     brouard  5159:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5160:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5161:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5162:       }
1.227     brouard  5163:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5164: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5165:        break;
1.224     brouard  5166: #else
1.227     brouard  5167:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5168:          if(firsthree == 0){
1.262     brouard  5169:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5170:            firsthree=1;
                   5171:          }
1.262     brouard  5172:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5173:          mw[++mi][i]=m;
                   5174:          mli=m;
                   5175:        }
                   5176:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5177:          nbwarn++;
                   5178:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5179:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5180:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5181:          }
                   5182:          break;
                   5183:        }
                   5184:        break;
1.224     brouard  5185: #endif
1.227     brouard  5186:       }/* End m >= lastpass */
1.126     brouard  5187:     }/* end while */
1.224     brouard  5188: 
1.227     brouard  5189:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5190:     /* After last pass */
1.224     brouard  5191: /* Treating death states */
1.214     brouard  5192:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5193:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5194:       /* } */
1.126     brouard  5195:       mi++;    /* Death is another wave */
                   5196:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5197:       /* Only death is a correct wave */
1.126     brouard  5198:       mw[mi][i]=m;
1.257     brouard  5199:     } /* else not in a death state */
1.224     brouard  5200: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5201:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5202:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5203:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5204:          nbwarn++;
                   5205:          if(firstfiv==0){
                   5206:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5207:            firstfiv=1;
                   5208:          }else{
                   5209:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5210:          }
                   5211:        }else{ /* Death occured afer last wave potential bias */
                   5212:          nberr++;
                   5213:          if(firstwo==0){
1.257     brouard  5214:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5215:            firstwo=1;
                   5216:          }
1.257     brouard  5217:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5218:        }
1.257     brouard  5219:       }else{ /* if date of interview is unknown */
1.227     brouard  5220:        /* death is known but not confirmed by death status at any wave */
                   5221:        if(firstfour==0){
                   5222:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5223:          firstfour=1;
                   5224:        }
                   5225:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5226:       }
1.224     brouard  5227:     } /* end if date of death is known */
                   5228: #endif
                   5229:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5230:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5231:     if(mi==0){
                   5232:       nbwarn++;
                   5233:       if(first==0){
1.227     brouard  5234:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5235:        first=1;
1.126     brouard  5236:       }
                   5237:       if(first==1){
1.227     brouard  5238:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5239:       }
                   5240:     } /* end mi==0 */
                   5241:   } /* End individuals */
1.214     brouard  5242:   /* wav and mw are no more changed */
1.223     brouard  5243:        
1.214     brouard  5244:   
1.126     brouard  5245:   for(i=1; i<=imx; i++){
                   5246:     for(mi=1; mi<wav[i];mi++){
                   5247:       if (stepm <=0)
1.227     brouard  5248:        dh[mi][i]=1;
1.126     brouard  5249:       else{
1.260     brouard  5250:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5251:          if (agedc[i] < 2*AGESUP) {
                   5252:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5253:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5254:            else if(j<0){
                   5255:              nberr++;
                   5256:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5257:              j=1; /* Temporary Dangerous patch */
                   5258:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5259:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5260:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5261:            }
                   5262:            k=k+1;
                   5263:            if (j >= jmax){
                   5264:              jmax=j;
                   5265:              ijmax=i;
                   5266:            }
                   5267:            if (j <= jmin){
                   5268:              jmin=j;
                   5269:              ijmin=i;
                   5270:            }
                   5271:            sum=sum+j;
                   5272:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5273:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5274:          }
                   5275:        }
                   5276:        else{
                   5277:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5278: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5279:                                        
1.227     brouard  5280:          k=k+1;
                   5281:          if (j >= jmax) {
                   5282:            jmax=j;
                   5283:            ijmax=i;
                   5284:          }
                   5285:          else if (j <= jmin){
                   5286:            jmin=j;
                   5287:            ijmin=i;
                   5288:          }
                   5289:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5290:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5291:          if(j<0){
                   5292:            nberr++;
                   5293:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5294:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5295:          }
                   5296:          sum=sum+j;
                   5297:        }
                   5298:        jk= j/stepm;
                   5299:        jl= j -jk*stepm;
                   5300:        ju= j -(jk+1)*stepm;
                   5301:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5302:          if(jl==0){
                   5303:            dh[mi][i]=jk;
                   5304:            bh[mi][i]=0;
                   5305:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5306:                  * to avoid the price of an extra matrix product in likelihood */
                   5307:            dh[mi][i]=jk+1;
                   5308:            bh[mi][i]=ju;
                   5309:          }
                   5310:        }else{
                   5311:          if(jl <= -ju){
                   5312:            dh[mi][i]=jk;
                   5313:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5314:                                 * is higher than the multiple of stepm and negative otherwise.
                   5315:                                 */
                   5316:          }
                   5317:          else{
                   5318:            dh[mi][i]=jk+1;
                   5319:            bh[mi][i]=ju;
                   5320:          }
                   5321:          if(dh[mi][i]==0){
                   5322:            dh[mi][i]=1; /* At least one step */
                   5323:            bh[mi][i]=ju; /* At least one step */
                   5324:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5325:          }
                   5326:        } /* end if mle */
1.126     brouard  5327:       }
                   5328:     } /* end wave */
                   5329:   }
                   5330:   jmean=sum/k;
                   5331:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5332:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5333: }
1.126     brouard  5334: 
                   5335: /*********** Tricode ****************************/
1.220     brouard  5336:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5337:  {
                   5338:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5339:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5340:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5341:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5342:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5343:     */
1.130     brouard  5344: 
1.242     brouard  5345:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5346:    int modmaxcovj=0; /* Modality max of covariates j */
                   5347:    int cptcode=0; /* Modality max of covariates j */
                   5348:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5349: 
                   5350: 
1.242     brouard  5351:    /* cptcoveff=0;  */
                   5352:    /* *cptcov=0; */
1.126     brouard  5353:  
1.242     brouard  5354:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5355: 
1.242     brouard  5356:    /* Loop on covariates without age and products and no quantitative variable */
                   5357:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5358:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5359:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5360:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5361:        switch(Fixed[k]) {
                   5362:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5363:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5364:           ij=(int)(covar[Tvar[k]][i]);
                   5365:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5366:            * If product of Vn*Vm, still boolean *:
                   5367:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5368:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5369:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5370:              modality of the nth covariate of individual i. */
                   5371:           if (ij > modmaxcovj)
                   5372:             modmaxcovj=ij; 
                   5373:           else if (ij < modmincovj) 
                   5374:             modmincovj=ij; 
                   5375:           if ((ij < -1) && (ij > NCOVMAX)){
                   5376:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5377:             exit(1);
                   5378:           }else
                   5379:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5380:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5381:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5382:           /* getting the maximum value of the modality of the covariate
                   5383:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5384:              female ies 1, then modmaxcovj=1.
                   5385:           */
                   5386:         } /* end for loop on individuals i */
                   5387:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5388:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5389:         cptcode=modmaxcovj;
                   5390:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5391:         /*for (i=0; i<=cptcode; i++) {*/
                   5392:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5393:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5394:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5395:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5396:             if( j != -1){
                   5397:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5398:                                  covariate for which somebody answered excluding 
                   5399:                                  undefined. Usually 2: 0 and 1. */
                   5400:             }
                   5401:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5402:                                     covariate for which somebody answered including 
                   5403:                                     undefined. Usually 3: -1, 0 and 1. */
                   5404:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5405:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5406:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5407:                        
1.242     brouard  5408:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5409:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5410:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5411:         /* modmincovj=3; modmaxcovj = 7; */
                   5412:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5413:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5414:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5415:         /* nbcode[Tvar[j]][ij]=k; */
                   5416:         /* nbcode[Tvar[j]][1]=0; */
                   5417:         /* nbcode[Tvar[j]][2]=1; */
                   5418:         /* nbcode[Tvar[j]][3]=2; */
                   5419:         /* To be continued (not working yet). */
                   5420:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5421:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5422:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5423:             break;
                   5424:           }
                   5425:           ij++;
                   5426:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5427:           cptcode = ij; /* New max modality for covar j */
                   5428:         } /* end of loop on modality i=-1 to 1 or more */
                   5429:         break;
                   5430:        case 1: /* Testing on varying covariate, could be simple and
                   5431:                * should look at waves or product of fixed *
                   5432:                * varying. No time to test -1, assuming 0 and 1 only */
                   5433:         ij=0;
                   5434:         for(i=0; i<=1;i++){
                   5435:           nbcode[Tvar[k]][++ij]=i;
                   5436:         }
                   5437:         break;
                   5438:        default:
                   5439:         break;
                   5440:        } /* end switch */
                   5441:      } /* end dummy test */
                   5442:     
                   5443:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5444:      /*        /\*recode from 0 *\/ */
                   5445:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5446:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5447:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5448:      /*        } */
                   5449:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5450:      /*        if (ij > ncodemax[j]) { */
                   5451:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5452:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5453:      /*          break; */
                   5454:      /*        } */
                   5455:      /*   }  /\* end of loop on modality k *\/ */
                   5456:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5457:   
                   5458:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5459:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5460:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5461:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5462:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5463:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5464:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5465:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5466:   
                   5467:    ij=0;
                   5468:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5469:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5470:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5471:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5472:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5473:        /* If product not in single variable we don't print results */
                   5474:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5475:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5476:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5477:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5478:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5479:        if(Fixed[k]!=0)
                   5480:         anyvaryingduminmodel=1;
                   5481:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5482:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5483:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5484:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5485:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5486:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5487:      } 
                   5488:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5489:    /* ij--; */
                   5490:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5491:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5492:                * because they can be excluded from the model and real
                   5493:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5494:    for(j=ij+1; j<= cptcovt; j++){
                   5495:      Tvaraff[j]=0;
                   5496:      Tmodelind[j]=0;
                   5497:    }
                   5498:    for(j=ntveff+1; j<= cptcovt; j++){
                   5499:      TmodelInvind[j]=0;
                   5500:    }
                   5501:    /* To be sorted */
                   5502:    ;
                   5503:  }
1.126     brouard  5504: 
1.145     brouard  5505: 
1.126     brouard  5506: /*********** Health Expectancies ****************/
                   5507: 
1.235     brouard  5508:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5509: 
                   5510: {
                   5511:   /* Health expectancies, no variances */
1.164     brouard  5512:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5513:   int nhstepma, nstepma; /* Decreasing with age */
                   5514:   double age, agelim, hf;
                   5515:   double ***p3mat;
                   5516:   double eip;
                   5517: 
1.238     brouard  5518:   /* pstamp(ficreseij); */
1.126     brouard  5519:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5520:   fprintf(ficreseij,"# Age");
                   5521:   for(i=1; i<=nlstate;i++){
                   5522:     for(j=1; j<=nlstate;j++){
                   5523:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5524:     }
                   5525:     fprintf(ficreseij," e%1d. ",i);
                   5526:   }
                   5527:   fprintf(ficreseij,"\n");
                   5528: 
                   5529:   
                   5530:   if(estepm < stepm){
                   5531:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5532:   }
                   5533:   else  hstepm=estepm;   
                   5534:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5535:    * This is mainly to measure the difference between two models: for example
                   5536:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5537:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5538:    * progression in between and thus overestimating or underestimating according
                   5539:    * to the curvature of the survival function. If, for the same date, we 
                   5540:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5541:    * to compare the new estimate of Life expectancy with the same linear 
                   5542:    * hypothesis. A more precise result, taking into account a more precise
                   5543:    * curvature will be obtained if estepm is as small as stepm. */
                   5544: 
                   5545:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5546:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5547:      nhstepm is the number of hstepm from age to agelim 
                   5548:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5549:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5550:      and note for a fixed period like estepm months */
                   5551:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5552:      survival function given by stepm (the optimization length). Unfortunately it
                   5553:      means that if the survival funtion is printed only each two years of age and if
                   5554:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5555:      results. So we changed our mind and took the option of the best precision.
                   5556:   */
                   5557:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5558: 
                   5559:   agelim=AGESUP;
                   5560:   /* If stepm=6 months */
                   5561:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5562:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5563:     
                   5564: /* nhstepm age range expressed in number of stepm */
                   5565:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5566:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5567:   /* if (stepm >= YEARM) hstepm=1;*/
                   5568:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5569:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5570: 
                   5571:   for (age=bage; age<=fage; age ++){ 
                   5572:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5573:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5574:     /* if (stepm >= YEARM) hstepm=1;*/
                   5575:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5576: 
                   5577:     /* If stepm=6 months */
                   5578:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5579:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5580:     
1.235     brouard  5581:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5582:     
                   5583:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5584:     
                   5585:     printf("%d|",(int)age);fflush(stdout);
                   5586:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5587:     
                   5588:     /* Computing expectancies */
                   5589:     for(i=1; i<=nlstate;i++)
                   5590:       for(j=1; j<=nlstate;j++)
                   5591:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5592:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5593:          
                   5594:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5595: 
                   5596:        }
                   5597: 
                   5598:     fprintf(ficreseij,"%3.0f",age );
                   5599:     for(i=1; i<=nlstate;i++){
                   5600:       eip=0;
                   5601:       for(j=1; j<=nlstate;j++){
                   5602:        eip +=eij[i][j][(int)age];
                   5603:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5604:       }
                   5605:       fprintf(ficreseij,"%9.4f", eip );
                   5606:     }
                   5607:     fprintf(ficreseij,"\n");
                   5608:     
                   5609:   }
                   5610:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5611:   printf("\n");
                   5612:   fprintf(ficlog,"\n");
                   5613:   
                   5614: }
                   5615: 
1.235     brouard  5616:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5617: 
                   5618: {
                   5619:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5620:      to initial status i, ei. .
1.126     brouard  5621:   */
                   5622:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5623:   int nhstepma, nstepma; /* Decreasing with age */
                   5624:   double age, agelim, hf;
                   5625:   double ***p3matp, ***p3matm, ***varhe;
                   5626:   double **dnewm,**doldm;
                   5627:   double *xp, *xm;
                   5628:   double **gp, **gm;
                   5629:   double ***gradg, ***trgradg;
                   5630:   int theta;
                   5631: 
                   5632:   double eip, vip;
                   5633: 
                   5634:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5635:   xp=vector(1,npar);
                   5636:   xm=vector(1,npar);
                   5637:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5638:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5639:   
                   5640:   pstamp(ficresstdeij);
                   5641:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5642:   fprintf(ficresstdeij,"# Age");
                   5643:   for(i=1; i<=nlstate;i++){
                   5644:     for(j=1; j<=nlstate;j++)
                   5645:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5646:     fprintf(ficresstdeij," e%1d. ",i);
                   5647:   }
                   5648:   fprintf(ficresstdeij,"\n");
                   5649: 
                   5650:   pstamp(ficrescveij);
                   5651:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5652:   fprintf(ficrescveij,"# Age");
                   5653:   for(i=1; i<=nlstate;i++)
                   5654:     for(j=1; j<=nlstate;j++){
                   5655:       cptj= (j-1)*nlstate+i;
                   5656:       for(i2=1; i2<=nlstate;i2++)
                   5657:        for(j2=1; j2<=nlstate;j2++){
                   5658:          cptj2= (j2-1)*nlstate+i2;
                   5659:          if(cptj2 <= cptj)
                   5660:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5661:        }
                   5662:     }
                   5663:   fprintf(ficrescveij,"\n");
                   5664:   
                   5665:   if(estepm < stepm){
                   5666:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5667:   }
                   5668:   else  hstepm=estepm;   
                   5669:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5670:    * This is mainly to measure the difference between two models: for example
                   5671:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5672:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5673:    * progression in between and thus overestimating or underestimating according
                   5674:    * to the curvature of the survival function. If, for the same date, we 
                   5675:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5676:    * to compare the new estimate of Life expectancy with the same linear 
                   5677:    * hypothesis. A more precise result, taking into account a more precise
                   5678:    * curvature will be obtained if estepm is as small as stepm. */
                   5679: 
                   5680:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5681:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5682:      nhstepm is the number of hstepm from age to agelim 
                   5683:      nstepm is the number of stepm from age to agelin. 
                   5684:      Look at hpijx to understand the reason of that which relies in memory size
                   5685:      and note for a fixed period like estepm months */
                   5686:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5687:      survival function given by stepm (the optimization length). Unfortunately it
                   5688:      means that if the survival funtion is printed only each two years of age and if
                   5689:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5690:      results. So we changed our mind and took the option of the best precision.
                   5691:   */
                   5692:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5693: 
                   5694:   /* If stepm=6 months */
                   5695:   /* nhstepm age range expressed in number of stepm */
                   5696:   agelim=AGESUP;
                   5697:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5698:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5699:   /* if (stepm >= YEARM) hstepm=1;*/
                   5700:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5701:   
                   5702:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5703:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5704:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5705:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5706:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5707:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5708: 
                   5709:   for (age=bage; age<=fage; age ++){ 
                   5710:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5711:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5712:     /* if (stepm >= YEARM) hstepm=1;*/
                   5713:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5714:                
1.126     brouard  5715:     /* If stepm=6 months */
                   5716:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5717:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5718:     
                   5719:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5720:                
1.126     brouard  5721:     /* Computing  Variances of health expectancies */
                   5722:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5723:        decrease memory allocation */
                   5724:     for(theta=1; theta <=npar; theta++){
                   5725:       for(i=1; i<=npar; i++){ 
1.222     brouard  5726:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5727:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5728:       }
1.235     brouard  5729:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5730:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5731:                        
1.126     brouard  5732:       for(j=1; j<= nlstate; j++){
1.222     brouard  5733:        for(i=1; i<=nlstate; i++){
                   5734:          for(h=0; h<=nhstepm-1; h++){
                   5735:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5736:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5737:          }
                   5738:        }
1.126     brouard  5739:       }
1.218     brouard  5740:                        
1.126     brouard  5741:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5742:        for(h=0; h<=nhstepm-1; h++){
                   5743:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5744:        }
1.126     brouard  5745:     }/* End theta */
                   5746:     
                   5747:     
                   5748:     for(h=0; h<=nhstepm-1; h++)
                   5749:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5750:        for(theta=1; theta <=npar; theta++)
                   5751:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5752:     
1.218     brouard  5753:                
1.222     brouard  5754:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5755:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5756:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5757:                
1.222     brouard  5758:     printf("%d|",(int)age);fflush(stdout);
                   5759:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5760:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5761:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5762:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5763:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5764:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5765:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5766:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5767:       }
                   5768:     }
1.218     brouard  5769:                
1.126     brouard  5770:     /* Computing expectancies */
1.235     brouard  5771:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5772:     for(i=1; i<=nlstate;i++)
                   5773:       for(j=1; j<=nlstate;j++)
1.222     brouard  5774:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5775:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5776:                                        
1.222     brouard  5777:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5778:                                        
1.222     brouard  5779:        }
1.269     brouard  5780: 
                   5781:     /* Standard deviation of expectancies ij */                
1.126     brouard  5782:     fprintf(ficresstdeij,"%3.0f",age );
                   5783:     for(i=1; i<=nlstate;i++){
                   5784:       eip=0.;
                   5785:       vip=0.;
                   5786:       for(j=1; j<=nlstate;j++){
1.222     brouard  5787:        eip += eij[i][j][(int)age];
                   5788:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5789:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5790:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5791:       }
                   5792:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5793:     }
                   5794:     fprintf(ficresstdeij,"\n");
1.218     brouard  5795:                
1.269     brouard  5796:     /* Variance of expectancies ij */          
1.126     brouard  5797:     fprintf(ficrescveij,"%3.0f",age );
                   5798:     for(i=1; i<=nlstate;i++)
                   5799:       for(j=1; j<=nlstate;j++){
1.222     brouard  5800:        cptj= (j-1)*nlstate+i;
                   5801:        for(i2=1; i2<=nlstate;i2++)
                   5802:          for(j2=1; j2<=nlstate;j2++){
                   5803:            cptj2= (j2-1)*nlstate+i2;
                   5804:            if(cptj2 <= cptj)
                   5805:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5806:          }
1.126     brouard  5807:       }
                   5808:     fprintf(ficrescveij,"\n");
1.218     brouard  5809:                
1.126     brouard  5810:   }
                   5811:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5812:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5813:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5814:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5815:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5816:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5817:   printf("\n");
                   5818:   fprintf(ficlog,"\n");
1.218     brouard  5819:        
1.126     brouard  5820:   free_vector(xm,1,npar);
                   5821:   free_vector(xp,1,npar);
                   5822:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5823:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5824:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5825: }
1.218     brouard  5826:  
1.126     brouard  5827: /************ Variance ******************/
1.235     brouard  5828:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5829:  {
1.279     brouard  5830:    /** Variance of health expectancies 
                   5831:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5832:     * double **newm;
                   5833:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5834:     */
1.218     brouard  5835:   
                   5836:    /* int movingaverage(); */
                   5837:    double **dnewm,**doldm;
                   5838:    double **dnewmp,**doldmp;
                   5839:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5840:    int k;
                   5841:    double *xp;
1.279     brouard  5842:    double **gp, **gm;  /**< for var eij */
                   5843:    double ***gradg, ***trgradg; /**< for var eij */
                   5844:    double **gradgp, **trgradgp; /**< for var p point j */
                   5845:    double *gpp, *gmp; /**< for var p point j */
                   5846:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5847:    double ***p3mat;
                   5848:    double age,agelim, hf;
                   5849:    /* double ***mobaverage; */
                   5850:    int theta;
                   5851:    char digit[4];
                   5852:    char digitp[25];
                   5853: 
                   5854:    char fileresprobmorprev[FILENAMELENGTH];
                   5855: 
                   5856:    if(popbased==1){
                   5857:      if(mobilav!=0)
                   5858:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5859:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5860:    }
                   5861:    else 
                   5862:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5863: 
1.218     brouard  5864:    /* if (mobilav!=0) { */
                   5865:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5866:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5867:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5868:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5869:    /*   } */
                   5870:    /* } */
                   5871: 
                   5872:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5873:    sprintf(digit,"%-d",ij);
                   5874:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5875:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5876:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5877:    strcat(fileresprobmorprev,fileresu);
                   5878:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5879:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5880:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5881:    }
                   5882:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5883:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5884:    pstamp(ficresprobmorprev);
                   5885:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5886:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5887:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5888:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5889:    }
                   5890:    for(j=1;j<=cptcoveff;j++) 
                   5891:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5892:    fprintf(ficresprobmorprev,"\n");
                   5893: 
1.218     brouard  5894:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5895:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5896:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5897:      for(i=1; i<=nlstate;i++)
                   5898:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5899:    }  
                   5900:    fprintf(ficresprobmorprev,"\n");
                   5901:   
                   5902:    fprintf(ficgp,"\n# Routine varevsij");
                   5903:    fprintf(ficgp,"\nunset title \n");
                   5904:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5905:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5906:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5907: 
1.218     brouard  5908:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5909:    pstamp(ficresvij);
                   5910:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5911:    if(popbased==1)
                   5912:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5913:    else
                   5914:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5915:    fprintf(ficresvij,"# Age");
                   5916:    for(i=1; i<=nlstate;i++)
                   5917:      for(j=1; j<=nlstate;j++)
                   5918:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5919:    fprintf(ficresvij,"\n");
                   5920: 
                   5921:    xp=vector(1,npar);
                   5922:    dnewm=matrix(1,nlstate,1,npar);
                   5923:    doldm=matrix(1,nlstate,1,nlstate);
                   5924:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5925:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5926: 
                   5927:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5928:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5929:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5930:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5931:   
1.218     brouard  5932:    if(estepm < stepm){
                   5933:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5934:    }
                   5935:    else  hstepm=estepm;   
                   5936:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5937:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5938:       nhstepm is the number of hstepm from age to agelim 
                   5939:       nstepm is the number of stepm from age to agelim. 
                   5940:       Look at function hpijx to understand why because of memory size limitations, 
                   5941:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5942:       survival function given by stepm (the optimization length). Unfortunately it
                   5943:       means that if the survival funtion is printed every two years of age and if
                   5944:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5945:       results. So we changed our mind and took the option of the best precision.
                   5946:    */
                   5947:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5948:    agelim = AGESUP;
                   5949:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5950:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5951:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5952:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5953:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5954:      gp=matrix(0,nhstepm,1,nlstate);
                   5955:      gm=matrix(0,nhstepm,1,nlstate);
                   5956:                
                   5957:                
                   5958:      for(theta=1; theta <=npar; theta++){
                   5959:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5960:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5961:        }
1.279     brouard  5962:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5963:        * returns into prlim .
                   5964:        */              
1.242     brouard  5965:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5966: 
                   5967:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5968:        if (popbased==1) {
                   5969:         if(mobilav ==0){
                   5970:           for(i=1; i<=nlstate;i++)
                   5971:             prlim[i][i]=probs[(int)age][i][ij];
                   5972:         }else{ /* mobilav */ 
                   5973:           for(i=1; i<=nlstate;i++)
                   5974:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5975:         }
                   5976:        }
1.279     brouard  5977:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5978:        */                      
                   5979:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   5980:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   5981:        * at horizon h in state j including mortality.
                   5982:        */
1.218     brouard  5983:        for(j=1; j<= nlstate; j++){
                   5984:         for(h=0; h<=nhstepm; h++){
                   5985:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5986:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5987:         }
                   5988:        }
1.279     brouard  5989:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  5990:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  5991:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  5992:        */
                   5993:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5994:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5995:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  5996:        }
                   5997:        
                   5998:        /* Again with minus shift */
1.218     brouard  5999:                        
                   6000:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6001:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6002:                        
1.242     brouard  6003:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6004:                        
                   6005:        if (popbased==1) {
                   6006:         if(mobilav ==0){
                   6007:           for(i=1; i<=nlstate;i++)
                   6008:             prlim[i][i]=probs[(int)age][i][ij];
                   6009:         }else{ /* mobilav */ 
                   6010:           for(i=1; i<=nlstate;i++)
                   6011:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6012:         }
                   6013:        }
                   6014:                        
1.235     brouard  6015:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6016:                        
                   6017:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6018:         for(h=0; h<=nhstepm; h++){
                   6019:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6020:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6021:         }
                   6022:        }
                   6023:        /* This for computing probability of death (h=1 means
                   6024:          computed over hstepm matrices product = hstepm*stepm months) 
                   6025:          as a weighted average of prlim.
                   6026:        */
                   6027:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6028:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6029:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6030:        }    
1.279     brouard  6031:        /* end shifting computations */
                   6032: 
                   6033:        /**< Computing gradient matrix at horizon h 
                   6034:        */
1.218     brouard  6035:        for(j=1; j<= nlstate; j++) /* vareij */
                   6036:         for(h=0; h<=nhstepm; h++){
                   6037:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6038:         }
1.279     brouard  6039:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6040:        */
                   6041:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6042:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6043:        }
                   6044:                        
                   6045:      } /* End theta */
1.279     brouard  6046:      
                   6047:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6048:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6049:                
                   6050:      for(h=0; h<=nhstepm; h++) /* veij */
                   6051:        for(j=1; j<=nlstate;j++)
                   6052:         for(theta=1; theta <=npar; theta++)
                   6053:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6054:                
                   6055:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6056:        for(theta=1; theta <=npar; theta++)
                   6057:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6058:      /**< as well as its transposed matrix 
                   6059:       */               
1.218     brouard  6060:                
                   6061:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6062:      for(i=1;i<=nlstate;i++)
                   6063:        for(j=1;j<=nlstate;j++)
                   6064:         vareij[i][j][(int)age] =0.;
1.279     brouard  6065: 
                   6066:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6067:       * and k (nhstepm) formula 15 of article
                   6068:       * Lievre-Brouard-Heathcote
                   6069:       */
                   6070:      
1.218     brouard  6071:      for(h=0;h<=nhstepm;h++){
                   6072:        for(k=0;k<=nhstepm;k++){
                   6073:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6074:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6075:         for(i=1;i<=nlstate;i++)
                   6076:           for(j=1;j<=nlstate;j++)
                   6077:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6078:        }
                   6079:      }
                   6080:                
1.279     brouard  6081:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6082:       * p.j overall mortality formula 49 but computed directly because
                   6083:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6084:       * wix is independent of theta.
                   6085:       */
1.218     brouard  6086:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6087:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6088:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6089:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6090:         varppt[j][i]=doldmp[j][i];
                   6091:      /* end ppptj */
                   6092:      /*  x centered again */
                   6093:                
1.242     brouard  6094:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6095:                
                   6096:      if (popbased==1) {
                   6097:        if(mobilav ==0){
                   6098:         for(i=1; i<=nlstate;i++)
                   6099:           prlim[i][i]=probs[(int)age][i][ij];
                   6100:        }else{ /* mobilav */ 
                   6101:         for(i=1; i<=nlstate;i++)
                   6102:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6103:        }
                   6104:      }
                   6105:                
                   6106:      /* This for computing probability of death (h=1 means
                   6107:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6108:        as a weighted average of prlim.
                   6109:      */
1.235     brouard  6110:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6111:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6112:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6113:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6114:      }    
                   6115:      /* end probability of death */
                   6116:                
                   6117:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6118:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6119:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6120:        for(i=1; i<=nlstate;i++){
                   6121:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6122:        }
                   6123:      } 
                   6124:      fprintf(ficresprobmorprev,"\n");
                   6125:                
                   6126:      fprintf(ficresvij,"%.0f ",age );
                   6127:      for(i=1; i<=nlstate;i++)
                   6128:        for(j=1; j<=nlstate;j++){
                   6129:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6130:        }
                   6131:      fprintf(ficresvij,"\n");
                   6132:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6133:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6134:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6135:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6136:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6137:    } /* End age */
                   6138:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6139:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6140:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6141:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6142:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6143:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6144:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6145:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6146:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6147:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6148:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6149:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6150:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6151:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6152:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6153:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6154:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6155:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6156:     */
1.218     brouard  6157:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6158:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6159: 
1.218     brouard  6160:    free_vector(xp,1,npar);
                   6161:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6162:    free_matrix(dnewm,1,nlstate,1,npar);
                   6163:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6164:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6165:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6166:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6167:    fclose(ficresprobmorprev);
                   6168:    fflush(ficgp);
                   6169:    fflush(fichtm); 
                   6170:  }  /* end varevsij */
1.126     brouard  6171: 
                   6172: /************ Variance of prevlim ******************/
1.269     brouard  6173:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6174: {
1.205     brouard  6175:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6176:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6177: 
1.268     brouard  6178:   double **dnewmpar,**doldm;
1.126     brouard  6179:   int i, j, nhstepm, hstepm;
                   6180:   double *xp;
                   6181:   double *gp, *gm;
                   6182:   double **gradg, **trgradg;
1.208     brouard  6183:   double **mgm, **mgp;
1.126     brouard  6184:   double age,agelim;
                   6185:   int theta;
                   6186:   
                   6187:   pstamp(ficresvpl);
                   6188:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6189:   fprintf(ficresvpl,"# Age ");
                   6190:   if(nresult >=1)
                   6191:     fprintf(ficresvpl," Result# ");
1.126     brouard  6192:   for(i=1; i<=nlstate;i++)
                   6193:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6194:   fprintf(ficresvpl,"\n");
                   6195: 
                   6196:   xp=vector(1,npar);
1.268     brouard  6197:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6198:   doldm=matrix(1,nlstate,1,nlstate);
                   6199:   
                   6200:   hstepm=1*YEARM; /* Every year of age */
                   6201:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6202:   agelim = AGESUP;
                   6203:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6204:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6205:     if (stepm >= YEARM) hstepm=1;
                   6206:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6207:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6208:     mgp=matrix(1,npar,1,nlstate);
                   6209:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6210:     gp=vector(1,nlstate);
                   6211:     gm=vector(1,nlstate);
                   6212: 
                   6213:     for(theta=1; theta <=npar; theta++){
                   6214:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6215:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6216:       }
1.209     brouard  6217:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6218:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6219:       else
1.235     brouard  6220:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6221:       for(i=1;i<=nlstate;i++){
1.126     brouard  6222:        gp[i] = prlim[i][i];
1.208     brouard  6223:        mgp[theta][i] = prlim[i][i];
                   6224:       }
1.126     brouard  6225:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6226:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6227:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6228:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6229:       else
1.235     brouard  6230:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6231:       for(i=1;i<=nlstate;i++){
1.126     brouard  6232:        gm[i] = prlim[i][i];
1.208     brouard  6233:        mgm[theta][i] = prlim[i][i];
                   6234:       }
1.126     brouard  6235:       for(i=1;i<=nlstate;i++)
                   6236:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6237:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6238:     } /* End theta */
                   6239: 
                   6240:     trgradg =matrix(1,nlstate,1,npar);
                   6241: 
                   6242:     for(j=1; j<=nlstate;j++)
                   6243:       for(theta=1; theta <=npar; theta++)
                   6244:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6245:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6246:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6247:     /*   for(j=1; j<=nlstate;j++){ */
                   6248:     /*         printf(" %d ",j); */
                   6249:     /*         for(theta=1; theta <=npar; theta++) */
                   6250:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6251:     /*         printf("\n "); */
                   6252:     /*   } */
                   6253:     /* } */
                   6254:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6255:     /*   printf("\n gradg %d ",(int)age); */
                   6256:     /*   for(j=1; j<=nlstate;j++){ */
                   6257:     /*         printf("%d ",j); */
                   6258:     /*         for(theta=1; theta <=npar; theta++) */
                   6259:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6260:     /*         printf("\n "); */
                   6261:     /*   } */
                   6262:     /* } */
1.126     brouard  6263: 
                   6264:     for(i=1;i<=nlstate;i++)
                   6265:       varpl[i][(int)age] =0.;
1.209     brouard  6266:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6267:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6268:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6269:     }else{
1.268     brouard  6270:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6271:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6272:     }
1.126     brouard  6273:     for(i=1;i<=nlstate;i++)
                   6274:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6275: 
                   6276:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6277:     if(nresult >=1)
                   6278:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6279:     for(i=1; i<=nlstate;i++)
                   6280:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6281:     fprintf(ficresvpl,"\n");
                   6282:     free_vector(gp,1,nlstate);
                   6283:     free_vector(gm,1,nlstate);
1.208     brouard  6284:     free_matrix(mgm,1,npar,1,nlstate);
                   6285:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6286:     free_matrix(gradg,1,npar,1,nlstate);
                   6287:     free_matrix(trgradg,1,nlstate,1,npar);
                   6288:   } /* End age */
                   6289: 
                   6290:   free_vector(xp,1,npar);
                   6291:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6292:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6293: 
                   6294: }
                   6295: 
                   6296: 
                   6297: /************ Variance of backprevalence limit ******************/
1.269     brouard  6298:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6299: {
                   6300:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6301:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6302: 
                   6303:   double **dnewmpar,**doldm;
                   6304:   int i, j, nhstepm, hstepm;
                   6305:   double *xp;
                   6306:   double *gp, *gm;
                   6307:   double **gradg, **trgradg;
                   6308:   double **mgm, **mgp;
                   6309:   double age,agelim;
                   6310:   int theta;
                   6311:   
                   6312:   pstamp(ficresvbl);
                   6313:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6314:   fprintf(ficresvbl,"# Age ");
                   6315:   if(nresult >=1)
                   6316:     fprintf(ficresvbl," Result# ");
                   6317:   for(i=1; i<=nlstate;i++)
                   6318:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6319:   fprintf(ficresvbl,"\n");
                   6320: 
                   6321:   xp=vector(1,npar);
                   6322:   dnewmpar=matrix(1,nlstate,1,npar);
                   6323:   doldm=matrix(1,nlstate,1,nlstate);
                   6324:   
                   6325:   hstepm=1*YEARM; /* Every year of age */
                   6326:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6327:   agelim = AGEINF;
                   6328:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6329:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6330:     if (stepm >= YEARM) hstepm=1;
                   6331:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6332:     gradg=matrix(1,npar,1,nlstate);
                   6333:     mgp=matrix(1,npar,1,nlstate);
                   6334:     mgm=matrix(1,npar,1,nlstate);
                   6335:     gp=vector(1,nlstate);
                   6336:     gm=vector(1,nlstate);
                   6337: 
                   6338:     for(theta=1; theta <=npar; theta++){
                   6339:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6340:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6341:       }
                   6342:       if(mobilavproj > 0 )
                   6343:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6344:       else
                   6345:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6346:       for(i=1;i<=nlstate;i++){
                   6347:        gp[i] = bprlim[i][i];
                   6348:        mgp[theta][i] = bprlim[i][i];
                   6349:       }
                   6350:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6351:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6352:        if(mobilavproj > 0 )
                   6353:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6354:        else
                   6355:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6356:       for(i=1;i<=nlstate;i++){
                   6357:        gm[i] = bprlim[i][i];
                   6358:        mgm[theta][i] = bprlim[i][i];
                   6359:       }
                   6360:       for(i=1;i<=nlstate;i++)
                   6361:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6362:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6363:     } /* End theta */
                   6364: 
                   6365:     trgradg =matrix(1,nlstate,1,npar);
                   6366: 
                   6367:     for(j=1; j<=nlstate;j++)
                   6368:       for(theta=1; theta <=npar; theta++)
                   6369:        trgradg[j][theta]=gradg[theta][j];
                   6370:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6371:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6372:     /*   for(j=1; j<=nlstate;j++){ */
                   6373:     /*         printf(" %d ",j); */
                   6374:     /*         for(theta=1; theta <=npar; theta++) */
                   6375:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6376:     /*         printf("\n "); */
                   6377:     /*   } */
                   6378:     /* } */
                   6379:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6380:     /*   printf("\n gradg %d ",(int)age); */
                   6381:     /*   for(j=1; j<=nlstate;j++){ */
                   6382:     /*         printf("%d ",j); */
                   6383:     /*         for(theta=1; theta <=npar; theta++) */
                   6384:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6385:     /*         printf("\n "); */
                   6386:     /*   } */
                   6387:     /* } */
                   6388: 
                   6389:     for(i=1;i<=nlstate;i++)
                   6390:       varbpl[i][(int)age] =0.;
                   6391:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6392:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6393:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6394:     }else{
                   6395:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6396:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6397:     }
                   6398:     for(i=1;i<=nlstate;i++)
                   6399:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6400: 
                   6401:     fprintf(ficresvbl,"%.0f ",age );
                   6402:     if(nresult >=1)
                   6403:       fprintf(ficresvbl,"%d ",nres );
                   6404:     for(i=1; i<=nlstate;i++)
                   6405:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6406:     fprintf(ficresvbl,"\n");
                   6407:     free_vector(gp,1,nlstate);
                   6408:     free_vector(gm,1,nlstate);
                   6409:     free_matrix(mgm,1,npar,1,nlstate);
                   6410:     free_matrix(mgp,1,npar,1,nlstate);
                   6411:     free_matrix(gradg,1,npar,1,nlstate);
                   6412:     free_matrix(trgradg,1,nlstate,1,npar);
                   6413:   } /* End age */
                   6414: 
                   6415:   free_vector(xp,1,npar);
                   6416:   free_matrix(doldm,1,nlstate,1,npar);
                   6417:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6418: 
                   6419: }
                   6420: 
                   6421: /************ Variance of one-step probabilities  ******************/
                   6422: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6423:  {
                   6424:    int i, j=0,  k1, l1, tj;
                   6425:    int k2, l2, j1,  z1;
                   6426:    int k=0, l;
                   6427:    int first=1, first1, first2;
                   6428:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6429:    double **dnewm,**doldm;
                   6430:    double *xp;
                   6431:    double *gp, *gm;
                   6432:    double **gradg, **trgradg;
                   6433:    double **mu;
                   6434:    double age, cov[NCOVMAX+1];
                   6435:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6436:    int theta;
                   6437:    char fileresprob[FILENAMELENGTH];
                   6438:    char fileresprobcov[FILENAMELENGTH];
                   6439:    char fileresprobcor[FILENAMELENGTH];
                   6440:    double ***varpij;
                   6441: 
                   6442:    strcpy(fileresprob,"PROB_"); 
                   6443:    strcat(fileresprob,fileres);
                   6444:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6445:      printf("Problem with resultfile: %s\n", fileresprob);
                   6446:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6447:    }
                   6448:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6449:    strcat(fileresprobcov,fileresu);
                   6450:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6451:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6452:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6453:    }
                   6454:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6455:    strcat(fileresprobcor,fileresu);
                   6456:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6457:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6458:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6459:    }
                   6460:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6461:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6462:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6463:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6464:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6465:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6466:    pstamp(ficresprob);
                   6467:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6468:    fprintf(ficresprob,"# Age");
                   6469:    pstamp(ficresprobcov);
                   6470:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6471:    fprintf(ficresprobcov,"# Age");
                   6472:    pstamp(ficresprobcor);
                   6473:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6474:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6475: 
                   6476: 
1.222     brouard  6477:    for(i=1; i<=nlstate;i++)
                   6478:      for(j=1; j<=(nlstate+ndeath);j++){
                   6479:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6480:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6481:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6482:      }  
                   6483:    /* fprintf(ficresprob,"\n");
                   6484:       fprintf(ficresprobcov,"\n");
                   6485:       fprintf(ficresprobcor,"\n");
                   6486:    */
                   6487:    xp=vector(1,npar);
                   6488:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6489:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6490:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6491:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6492:    first=1;
                   6493:    fprintf(ficgp,"\n# Routine varprob");
                   6494:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6495:    fprintf(fichtm,"\n");
                   6496: 
1.266     brouard  6497:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6498:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6499:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6500: and drawn. It helps understanding how is the covariance between two incidences.\
                   6501:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6502:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6503: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6504: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6505: standard deviations wide on each axis. <br>\
                   6506:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6507:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6508: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6509: 
1.222     brouard  6510:    cov[1]=1;
                   6511:    /* tj=cptcoveff; */
1.225     brouard  6512:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6513:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6514:    j1=0;
1.224     brouard  6515:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6516:      if  (cptcovn>0) {
                   6517:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6518:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6519:        fprintf(ficresprob, "**********\n#\n");
                   6520:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6521:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6522:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6523:                        
1.222     brouard  6524:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6525:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6526:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6527:                        
                   6528:                        
1.222     brouard  6529:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6530:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6531:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6532:                        
1.222     brouard  6533:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6534:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6535:        fprintf(ficresprobcor, "**********\n#");    
                   6536:        if(invalidvarcomb[j1]){
                   6537:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6538:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6539:         continue;
                   6540:        }
                   6541:      }
                   6542:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6543:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6544:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6545:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6546:      for (age=bage; age<=fage; age ++){ 
                   6547:        cov[2]=age;
                   6548:        if(nagesqr==1)
                   6549:         cov[3]= age*age;
                   6550:        for (k=1; k<=cptcovn;k++) {
                   6551:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6552:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6553:                                                                    * 1  1 1 1 1
                   6554:                                                                    * 2  2 1 1 1
                   6555:                                                                    * 3  1 2 1 1
                   6556:                                                                    */
                   6557:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6558:        }
                   6559:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6560:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6561:        for (k=1; k<=cptcovprod;k++)
                   6562:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6563:                        
                   6564:                        
1.222     brouard  6565:        for(theta=1; theta <=npar; theta++){
                   6566:         for(i=1; i<=npar; i++)
                   6567:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6568:                                
1.222     brouard  6569:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6570:                                
1.222     brouard  6571:         k=0;
                   6572:         for(i=1; i<= (nlstate); i++){
                   6573:           for(j=1; j<=(nlstate+ndeath);j++){
                   6574:             k=k+1;
                   6575:             gp[k]=pmmij[i][j];
                   6576:           }
                   6577:         }
1.220     brouard  6578:                                
1.222     brouard  6579:         for(i=1; i<=npar; i++)
                   6580:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6581:                                
1.222     brouard  6582:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6583:         k=0;
                   6584:         for(i=1; i<=(nlstate); i++){
                   6585:           for(j=1; j<=(nlstate+ndeath);j++){
                   6586:             k=k+1;
                   6587:             gm[k]=pmmij[i][j];
                   6588:           }
                   6589:         }
1.220     brouard  6590:                                
1.222     brouard  6591:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6592:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6593:        }
1.126     brouard  6594: 
1.222     brouard  6595:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6596:         for(theta=1; theta <=npar; theta++)
                   6597:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6598:                        
1.222     brouard  6599:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6600:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6601:                        
1.222     brouard  6602:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6603:                        
1.222     brouard  6604:        k=0;
                   6605:        for(i=1; i<=(nlstate); i++){
                   6606:         for(j=1; j<=(nlstate+ndeath);j++){
                   6607:           k=k+1;
                   6608:           mu[k][(int) age]=pmmij[i][j];
                   6609:         }
                   6610:        }
                   6611:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6612:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6613:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6614:                        
1.222     brouard  6615:        /*printf("\n%d ",(int)age);
                   6616:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6617:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6618:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6619:         }*/
1.220     brouard  6620:                        
1.222     brouard  6621:        fprintf(ficresprob,"\n%d ",(int)age);
                   6622:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6623:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6624:                        
1.222     brouard  6625:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6626:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6627:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6628:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6629:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6630:        }
                   6631:        i=0;
                   6632:        for (k=1; k<=(nlstate);k++){
                   6633:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6634:           i++;
                   6635:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6636:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6637:           for (j=1; j<=i;j++){
                   6638:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6639:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6640:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6641:           }
                   6642:         }
                   6643:        }/* end of loop for state */
                   6644:      } /* end of loop for age */
                   6645:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6646:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6647:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6648:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6649:     
                   6650:      /* Confidence intervalle of pij  */
                   6651:      /*
                   6652:        fprintf(ficgp,"\nunset parametric;unset label");
                   6653:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6654:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6655:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6656:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6657:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6658:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6659:      */
                   6660:                
                   6661:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6662:      first1=1;first2=2;
                   6663:      for (k2=1; k2<=(nlstate);k2++){
                   6664:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6665:         if(l2==k2) continue;
                   6666:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6667:         for (k1=1; k1<=(nlstate);k1++){
                   6668:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6669:             if(l1==k1) continue;
                   6670:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6671:             if(i<=j) continue;
                   6672:             for (age=bage; age<=fage; age ++){ 
                   6673:               if ((int)age %5==0){
                   6674:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6675:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6676:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6677:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6678:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6679:                 c12=cv12/sqrt(v1*v2);
                   6680:                 /* Computing eigen value of matrix of covariance */
                   6681:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6682:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6683:                 if ((lc2 <0) || (lc1 <0) ){
                   6684:                   if(first2==1){
                   6685:                     first1=0;
                   6686:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6687:                   }
                   6688:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6689:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6690:                   /* lc2=fabs(lc2); */
                   6691:                 }
1.220     brouard  6692:                                                                
1.222     brouard  6693:                 /* Eigen vectors */
1.280     brouard  6694:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6695:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6696:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6697:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6698:                 }else
                   6699:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6700:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6701:                 v21=(lc1-v1)/cv12*v11;
                   6702:                 v12=-v21;
                   6703:                 v22=v11;
                   6704:                 tnalp=v21/v11;
                   6705:                 if(first1==1){
                   6706:                   first1=0;
                   6707:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6708:                 }
                   6709:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6710:                 /*printf(fignu*/
                   6711:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6712:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6713:                 if(first==1){
                   6714:                   first=0;
                   6715:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6716:                   fprintf(ficgp,"\nset parametric;unset label");
                   6717:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6718:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6719:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6720:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6721: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6722:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6723:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6724:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6725:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6726:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6727:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6728:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6729:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6730:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6731:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6732:                 }else{
                   6733:                   first=0;
                   6734:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6735:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6736:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6737:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6738:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6739:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6740:                 }/* if first */
                   6741:               } /* age mod 5 */
                   6742:             } /* end loop age */
                   6743:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6744:             first=1;
                   6745:           } /*l12 */
                   6746:         } /* k12 */
                   6747:        } /*l1 */
                   6748:      }/* k1 */
                   6749:    }  /* loop on combination of covariates j1 */
                   6750:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6751:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6752:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6753:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6754:    free_vector(xp,1,npar);
                   6755:    fclose(ficresprob);
                   6756:    fclose(ficresprobcov);
                   6757:    fclose(ficresprobcor);
                   6758:    fflush(ficgp);
                   6759:    fflush(fichtmcov);
                   6760:  }
1.126     brouard  6761: 
                   6762: 
                   6763: /******************* Printing html file ***********/
1.201     brouard  6764: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6765:                  int lastpass, int stepm, int weightopt, char model[],\
                   6766:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6767:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6768:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6769:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6770:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6771: 
                   6772:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6773:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6774: </ul>");
1.237     brouard  6775:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6776: </ul>", model);
1.214     brouard  6777:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6778:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6779:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6780:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6781:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6782:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6783:    fprintf(fichtm,"\
                   6784:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6785:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6786:    fprintf(fichtm,"\
1.217     brouard  6787:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6788:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6789:    fprintf(fichtm,"\
1.126     brouard  6790:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6791:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6792:    fprintf(fichtm,"\
1.217     brouard  6793:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6794:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6795:    fprintf(fichtm,"\
1.211     brouard  6796:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6797:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6798:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6799:    if(prevfcast==1){
                   6800:      fprintf(fichtm,"\
                   6801:  - Prevalence projections by age and states:                           \
1.201     brouard  6802:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6803:    }
1.126     brouard  6804: 
                   6805: 
1.225     brouard  6806:    m=pow(2,cptcoveff);
1.222     brouard  6807:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6808: 
1.264     brouard  6809:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6810: 
                   6811:    jj1=0;
                   6812: 
                   6813:    fprintf(fichtm," \n<ul>");
                   6814:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6815:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6816:      if(m != 1 && TKresult[nres]!= k1)
                   6817:        continue;
                   6818:      jj1++;
                   6819:      if (cptcovn > 0) {
                   6820:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6821:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6822:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6823:        }
                   6824:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6825:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6826:        }
                   6827:        fprintf(fichtm,"\">");
                   6828:        
                   6829:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6830:        fprintf(fichtm,"************ Results for covariates");
                   6831:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6832:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6833:        }
                   6834:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6835:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6836:        }
                   6837:        if(invalidvarcomb[k1]){
                   6838:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6839:         continue;
                   6840:        }
                   6841:        fprintf(fichtm,"</a></li>");
                   6842:      } /* cptcovn >0 */
                   6843:    }
                   6844:      fprintf(fichtm," \n</ul>");
                   6845: 
1.222     brouard  6846:    jj1=0;
1.237     brouard  6847: 
                   6848:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6849:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6850:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6851:        continue;
1.220     brouard  6852: 
1.222     brouard  6853:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6854:      jj1++;
                   6855:      if (cptcovn > 0) {
1.264     brouard  6856:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6857:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6858:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6859:        }
                   6860:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6861:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6862:        }
                   6863:        fprintf(fichtm,"\"</a>");
                   6864:  
1.222     brouard  6865:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6866:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6867:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6868:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6869:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6870:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6871:        }
1.237     brouard  6872:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6873:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6874:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6875:       }
                   6876:        
1.230     brouard  6877:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6878:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6879:        if(invalidvarcomb[k1]){
                   6880:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6881:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6882:         continue;
                   6883:        }
                   6884:      }
                   6885:      /* aij, bij */
1.259     brouard  6886:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6887: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6888:      /* Pij */
1.241     brouard  6889:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6890: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6891:      /* Quasi-incidences */
                   6892:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6893:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6894:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6895: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6896: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6897:      /* Survival functions (period) in state j */
                   6898:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6899:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6900: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6901:      }
                   6902:      /* State specific survival functions (period) */
                   6903:      for(cpt=1; cpt<=nlstate;cpt++){
                   6904:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6905:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6906:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6907:      }
                   6908:      /* Period (stable) prevalence in each health state */
                   6909:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6910:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6911: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6912:      }
                   6913:      if(backcast==1){
                   6914:        /* Period (stable) back prevalence in each health state */
                   6915:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6916:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6917: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6918:        }
1.217     brouard  6919:      }
1.222     brouard  6920:      if(prevfcast==1){
                   6921:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6922:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6923:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6924: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6925:        }
                   6926:      }
1.268     brouard  6927:      if(backcast==1){
                   6928:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6929:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6930:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6931:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6932:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6933: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6934:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6935:        }
                   6936:      }
1.220     brouard  6937:         
1.222     brouard  6938:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6939:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6940: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6941:      }
                   6942:      /* } /\* end i1 *\/ */
                   6943:    }/* End k1 */
                   6944:    fprintf(fichtm,"</ul>");
1.126     brouard  6945: 
1.222     brouard  6946:    fprintf(fichtm,"\
1.126     brouard  6947: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6948:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6949:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6950: But because parameters are usually highly correlated (a higher incidence of disability \
                   6951: and a higher incidence of recovery can give very close observed transition) it might \
                   6952: be very useful to look not only at linear confidence intervals estimated from the \
                   6953: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6954: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6955: covariance matrix of the one-step probabilities. \
                   6956: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6957: 
1.222     brouard  6958:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6959:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6960:    fprintf(fichtm,"\
1.126     brouard  6961:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6962:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6963: 
1.222     brouard  6964:    fprintf(fichtm,"\
1.126     brouard  6965:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6966:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6967:    fprintf(fichtm,"\
1.126     brouard  6968:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6969:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6970:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6971:    fprintf(fichtm,"\
1.126     brouard  6972:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6973:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6974:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6975:    fprintf(fichtm,"\
1.128     brouard  6976:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6977:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6978:    fprintf(fichtm,"\
1.128     brouard  6979:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6980:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6981:    fprintf(fichtm,"\
1.126     brouard  6982:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6983:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6984: 
                   6985: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6986: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6987: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6988: /*     <br>",fileres,fileres,fileres,fileres); */
                   6989: /*  else  */
                   6990: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6991:    fflush(fichtm);
                   6992:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6993: 
1.225     brouard  6994:    m=pow(2,cptcoveff);
1.222     brouard  6995:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6996: 
1.222     brouard  6997:    jj1=0;
1.237     brouard  6998: 
1.241     brouard  6999:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7000:    for(k1=1; k1<=m;k1++){
1.253     brouard  7001:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7002:        continue;
1.222     brouard  7003:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7004:      jj1++;
1.126     brouard  7005:      if (cptcovn > 0) {
                   7006:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7007:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7008:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7009:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7010:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7011:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7012:       }
                   7013: 
1.126     brouard  7014:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7015: 
1.222     brouard  7016:        if(invalidvarcomb[k1]){
                   7017:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7018:         continue;
                   7019:        }
1.126     brouard  7020:      }
                   7021:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7022:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7023: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7024: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7025:      }
                   7026:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7027: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7028: true period expectancies (those weighted with period prevalences are also\
                   7029:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7030:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7031: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7032:      /* } /\* end i1 *\/ */
                   7033:    }/* End k1 */
1.241     brouard  7034:   }/* End nres */
1.222     brouard  7035:    fprintf(fichtm,"</ul>");
                   7036:    fflush(fichtm);
1.126     brouard  7037: }
                   7038: 
                   7039: /******************* Gnuplot file **************/
1.270     brouard  7040: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7041: 
                   7042:   char dirfileres[132],optfileres[132];
1.264     brouard  7043:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7044:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7045:   int lv=0, vlv=0, kl=0;
1.130     brouard  7046:   int ng=0;
1.201     brouard  7047:   int vpopbased;
1.223     brouard  7048:   int ioffset; /* variable offset for columns */
1.270     brouard  7049:   int iyearc=1; /* variable column for year of projection  */
                   7050:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7051:   int nres=0; /* Index of resultline */
1.266     brouard  7052:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7053: 
1.126     brouard  7054: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7055: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7056: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7057: /*   } */
                   7058: 
                   7059:   /*#ifdef windows */
                   7060:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7061:   /*#endif */
1.225     brouard  7062:   m=pow(2,cptcoveff);
1.126     brouard  7063: 
1.274     brouard  7064:   /* diagram of the model */
                   7065:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7066:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7067:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7068:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7069: 
                   7070:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7071:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7072:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7073:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7074:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7075:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7076:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7077: 
1.202     brouard  7078:   /* Contribution to likelihood */
                   7079:   /* Plot the probability implied in the likelihood */
1.223     brouard  7080:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7081:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7082:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7083:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7084: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7085:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7086: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7087:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7088:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7089:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7090:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7091:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7092:   for (i=1; i<= nlstate ; i ++) {
                   7093:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7094:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7095:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7096:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7097:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7098:     }
                   7099:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7100:   }
                   7101:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7102:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7103:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7104:   fprintf(ficgp,"\nset out;unset log\n");
                   7105:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7106: 
1.126     brouard  7107:   strcpy(dirfileres,optionfilefiname);
                   7108:   strcpy(optfileres,"vpl");
1.223     brouard  7109:   /* 1eme*/
1.238     brouard  7110:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7111:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7112:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7113:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7114:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7115:          continue;
                   7116:        /* We are interested in selected combination by the resultline */
1.246     brouard  7117:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7118:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7119:        strcpy(gplotlabel,"(");
1.238     brouard  7120:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7121:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7122:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7123:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7124:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7125:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7126:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7127:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7128:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7129:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7130:        }
                   7131:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7132:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7133:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7134:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7135:        }
                   7136:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7137:        /* printf("\n#\n"); */
1.238     brouard  7138:        fprintf(ficgp,"\n#\n");
                   7139:        if(invalidvarcomb[k1]){
1.260     brouard  7140:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7141:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7142:          continue;
                   7143:        }
1.235     brouard  7144:       
1.241     brouard  7145:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7146:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7147:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7148:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7149:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7150:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7151:       /* k1-1 error should be nres-1*/
1.238     brouard  7152:        for (i=1; i<= nlstate ; i ++) {
                   7153:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7154:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7155:        }
1.260     brouard  7156:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7157:        for (i=1; i<= nlstate ; i ++) {
                   7158:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7159:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7160:        } 
1.260     brouard  7161:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7162:        for (i=1; i<= nlstate ; i ++) {
                   7163:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7164:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7165:        }  
1.265     brouard  7166:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7167:        
                   7168:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7169:         if(cptcoveff ==0){
1.271     brouard  7170:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7171:        }else{
                   7172:          kl=0;
                   7173:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7174:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7175:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7176:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7177:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7178:            vlv= nbcode[Tvaraff[k]][lv];
                   7179:            kl++;
                   7180:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7181:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7182:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7183:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7184:            if(k==cptcoveff){
                   7185:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7186:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7187:            }else{
                   7188:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7189:              kl++;
                   7190:            }
                   7191:          } /* end covariate */
                   7192:        } /* end if no covariate */
                   7193: 
1.238     brouard  7194:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7195:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7196:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7197:          if(cptcoveff ==0){
1.245     brouard  7198:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7199:          }else{
                   7200:            kl=0;
                   7201:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7202:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7203:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7204:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7205:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7206:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7207:              kl++;
1.238     brouard  7208:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7209:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7210:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7211:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7212:              if(k==cptcoveff){
1.245     brouard  7213:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7214:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7215:              }else{
                   7216:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7217:                kl++;
                   7218:              }
                   7219:            } /* end covariate */
                   7220:          } /* end if no covariate */
1.268     brouard  7221:          if(backcast == 1){
                   7222:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7223:            /* k1-1 error should be nres-1*/
                   7224:            for (i=1; i<= nlstate ; i ++) {
                   7225:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7226:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7227:            }
1.271     brouard  7228:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7229:            for (i=1; i<= nlstate ; i ++) {
                   7230:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7231:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7232:            } 
1.276     brouard  7233:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7234:            for (i=1; i<= nlstate ; i ++) {
                   7235:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7236:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7237:            } 
1.274     brouard  7238:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7239:          } /* end if backprojcast */
1.238     brouard  7240:        } /* end if backcast */
1.276     brouard  7241:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7242:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7243:       } /* nres */
1.201     brouard  7244:     } /* k1 */
                   7245:   } /* cpt */
1.235     brouard  7246: 
                   7247:   
1.126     brouard  7248:   /*2 eme*/
1.238     brouard  7249:   for (k1=1; k1<= m ; k1 ++){  
                   7250:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7251:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7252:        continue;
                   7253:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7254:       strcpy(gplotlabel,"(");
1.238     brouard  7255:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7256:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7257:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7258:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7259:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7260:        vlv= nbcode[Tvaraff[k]][lv];
                   7261:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7262:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7263:       }
1.237     brouard  7264:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7265:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7266:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7267:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7268:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7269:       }
1.264     brouard  7270:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7271:       fprintf(ficgp,"\n#\n");
1.223     brouard  7272:       if(invalidvarcomb[k1]){
                   7273:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7274:        continue;
                   7275:       }
1.219     brouard  7276:                        
1.241     brouard  7277:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7278:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7279:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7280:        if(vpopbased==0){
1.238     brouard  7281:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7282:        }else
1.238     brouard  7283:          fprintf(ficgp,"\nreplot ");
                   7284:        for (i=1; i<= nlstate+1 ; i ++) {
                   7285:          k=2*i;
1.261     brouard  7286:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7287:          for (j=1; j<= nlstate+1 ; j ++) {
                   7288:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7289:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7290:          }   
                   7291:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7292:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7293:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7294:          for (j=1; j<= nlstate+1 ; j ++) {
                   7295:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7296:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7297:          }   
                   7298:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7299:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7300:          for (j=1; j<= nlstate+1 ; j ++) {
                   7301:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7302:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7303:          }   
                   7304:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7305:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7306:        } /* state */
                   7307:       } /* vpopbased */
1.264     brouard  7308:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7309:     } /* end nres */
                   7310:   } /* k1 end 2 eme*/
                   7311:        
                   7312:        
                   7313:   /*3eme*/
                   7314:   for (k1=1; k1<= m ; k1 ++){
                   7315:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7316:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7317:        continue;
                   7318: 
                   7319:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7320:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7321:        strcpy(gplotlabel,"(");
1.238     brouard  7322:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7323:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7324:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7325:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7326:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7327:          vlv= nbcode[Tvaraff[k]][lv];
                   7328:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7329:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7330:        }
                   7331:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7332:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7333:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7334:        }       
1.264     brouard  7335:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7336:        fprintf(ficgp,"\n#\n");
                   7337:        if(invalidvarcomb[k1]){
                   7338:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7339:          continue;
                   7340:        }
                   7341:                        
                   7342:        /*       k=2+nlstate*(2*cpt-2); */
                   7343:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7344:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7345:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7346:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7347: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7348:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7349:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7350:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7351:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7352:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7353:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7354:                                
1.238     brouard  7355:        */
                   7356:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7357:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7358:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7359:                                
1.238     brouard  7360:        } 
1.261     brouard  7361:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7362:       }
1.264     brouard  7363:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7364:     } /* end nres */
                   7365:   } /* end kl 3eme */
1.126     brouard  7366:   
1.223     brouard  7367:   /* 4eme */
1.201     brouard  7368:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7369:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7370:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7371:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7372:        continue;
1.238     brouard  7373:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7374:        strcpy(gplotlabel,"(");
1.238     brouard  7375:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7376:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7377:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7378:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7379:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7380:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7381:          vlv= nbcode[Tvaraff[k]][lv];
                   7382:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7383:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7384:        }
                   7385:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7386:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7387:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7388:        }       
1.264     brouard  7389:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7390:        fprintf(ficgp,"\n#\n");
                   7391:        if(invalidvarcomb[k1]){
                   7392:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7393:          continue;
1.223     brouard  7394:        }
1.238     brouard  7395:       
1.241     brouard  7396:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7397:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7398:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7399: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7400:        k=3;
                   7401:        for (i=1; i<= nlstate ; i ++){
                   7402:          if(i==1){
                   7403:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7404:          }else{
                   7405:            fprintf(ficgp,", '' ");
                   7406:          }
                   7407:          l=(nlstate+ndeath)*(i-1)+1;
                   7408:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7409:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7410:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7411:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7412:        } /* nlstate */
1.264     brouard  7413:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7414:       } /* end cpt state*/ 
                   7415:     } /* end nres */
                   7416:   } /* end covariate k1 */  
                   7417: 
1.220     brouard  7418: /* 5eme */
1.201     brouard  7419:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7420:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7421:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7422:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7423:        continue;
1.238     brouard  7424:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7425:        strcpy(gplotlabel,"(");
1.238     brouard  7426:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7427:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7428:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7429:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7430:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7431:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7432:          vlv= nbcode[Tvaraff[k]][lv];
                   7433:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7434:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7435:        }
                   7436:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7437:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7438:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7439:        }       
1.264     brouard  7440:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7441:        fprintf(ficgp,"\n#\n");
                   7442:        if(invalidvarcomb[k1]){
                   7443:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7444:          continue;
                   7445:        }
1.227     brouard  7446:       
1.241     brouard  7447:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7448:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7449:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7450: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7451:        k=3;
                   7452:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7453:          if(j==1)
                   7454:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7455:          else
                   7456:            fprintf(ficgp,", '' ");
                   7457:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7458:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7459:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7460:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7461:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7462:        } /* nlstate */
                   7463:        fprintf(ficgp,", '' ");
                   7464:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7465:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7466:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7467:          if(j < nlstate)
                   7468:            fprintf(ficgp,"$%d +",k+l);
                   7469:          else
                   7470:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7471:        }
1.264     brouard  7472:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7473:       } /* end cpt state*/ 
                   7474:     } /* end covariate */  
                   7475:   } /* end nres */
1.227     brouard  7476:   
1.220     brouard  7477: /* 6eme */
1.202     brouard  7478:   /* CV preval stable (period) for each covariate */
1.237     brouard  7479:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7480:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7481:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7482:       continue;
1.255     brouard  7483:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7484:       strcpy(gplotlabel,"(");      
1.211     brouard  7485:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7486:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7487:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7488:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7489:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7490:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7491:        vlv= nbcode[Tvaraff[k]][lv];
                   7492:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7493:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7494:       }
1.237     brouard  7495:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7496:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7497:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7498:       }        
1.264     brouard  7499:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7500:       fprintf(ficgp,"\n#\n");
1.223     brouard  7501:       if(invalidvarcomb[k1]){
1.227     brouard  7502:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7503:        continue;
1.223     brouard  7504:       }
1.227     brouard  7505:       
1.241     brouard  7506:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7507:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7508:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7509: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7510:       k=3; /* Offset */
1.255     brouard  7511:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7512:        if(i==1)
                   7513:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7514:        else
                   7515:          fprintf(ficgp,", '' ");
1.255     brouard  7516:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7517:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7518:        for (j=2; j<= nlstate ; j ++)
                   7519:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7520:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7521:       } /* nlstate */
1.264     brouard  7522:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7523:     } /* end cpt state*/ 
                   7524:   } /* end covariate */  
1.227     brouard  7525:   
                   7526:   
1.220     brouard  7527: /* 7eme */
1.218     brouard  7528:   if(backcast == 1){
1.217     brouard  7529:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7530:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7531:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7532:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7533:        continue;
1.268     brouard  7534:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7535:        strcpy(gplotlabel,"(");      
                   7536:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7537:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7538:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7539:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7540:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7541:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7542:          vlv= nbcode[Tvaraff[k]][lv];
                   7543:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7544:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7545:        }
1.237     brouard  7546:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7547:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7548:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7549:        }       
1.264     brouard  7550:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7551:        fprintf(ficgp,"\n#\n");
                   7552:        if(invalidvarcomb[k1]){
                   7553:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7554:          continue;
                   7555:        }
                   7556:        
1.241     brouard  7557:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7558:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7559:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7560: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7561:        k=3; /* Offset */
1.268     brouard  7562:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7563:          if(i==1)
                   7564:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7565:          else
                   7566:            fprintf(ficgp,", '' ");
                   7567:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7568:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7569:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7570:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7571:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7572:          /* for (j=2; j<= nlstate ; j ++) */
                   7573:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7574:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7575:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7576:        } /* nlstate */
1.264     brouard  7577:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7578:       } /* end cpt state*/ 
                   7579:     } /* end covariate */  
                   7580:   } /* End if backcast */
                   7581:   
1.223     brouard  7582:   /* 8eme */
1.218     brouard  7583:   if(prevfcast==1){
                   7584:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7585:     
1.237     brouard  7586:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7587:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7588:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7589:        continue;
1.211     brouard  7590:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7591:        strcpy(gplotlabel,"(");      
1.227     brouard  7592:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7593:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7594:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7595:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7596:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7597:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7598:          vlv= nbcode[Tvaraff[k]][lv];
                   7599:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7600:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7601:        }
1.237     brouard  7602:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7603:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7604:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7605:        }       
1.264     brouard  7606:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7607:        fprintf(ficgp,"\n#\n");
                   7608:        if(invalidvarcomb[k1]){
                   7609:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7610:          continue;
                   7611:        }
                   7612:        
                   7613:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7614:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7615:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7616:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7617: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7618: 
                   7619:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7620:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7621:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7622:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7623:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7624:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7625:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7626:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7627:          if(i==istart){
1.227     brouard  7628:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7629:          }else{
                   7630:            fprintf(ficgp,",\\\n '' ");
                   7631:          }
                   7632:          if(cptcoveff ==0){ /* No covariate */
                   7633:            ioffset=2; /* Age is in 2 */
                   7634:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7635:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7636:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7637:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7638:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7639:            if(i==nlstate+1){
1.270     brouard  7640:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7641:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7642:              fprintf(ficgp,",\\\n '' ");
                   7643:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7644:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7645:                     offyear,                           \
1.268     brouard  7646:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7647:            }else
1.227     brouard  7648:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7649:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7650:          }else{ /* more than 2 covariates */
1.270     brouard  7651:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7652:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7653:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7654:            iyearc=ioffset-1;
                   7655:            iagec=ioffset;
1.227     brouard  7656:            fprintf(ficgp," u %d:(",ioffset); 
                   7657:            kl=0;
                   7658:            strcpy(gplotcondition,"(");
                   7659:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7660:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7661:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7662:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7663:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7664:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7665:              kl++;
                   7666:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7667:              kl++;
                   7668:              if(k <cptcoveff && cptcoveff>1)
                   7669:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7670:            }
                   7671:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7672:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7673:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7674:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7675:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7676:            if(i==nlstate+1){
1.270     brouard  7677:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7678:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7679:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7680:              fprintf(ficgp," u %d:(",iagec); 
                   7681:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7682:                      iyearc, iagec, offyear,                           \
                   7683:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7684: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7685:            }else{
                   7686:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7687:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7688:            }
                   7689:          } /* end if covariate */
                   7690:        } /* nlstate */
1.264     brouard  7691:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7692:       } /* end cpt state*/
                   7693:     } /* end covariate */
                   7694:   } /* End if prevfcast */
1.227     brouard  7695:   
1.268     brouard  7696:   if(backcast==1){
                   7697:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7698:     
                   7699:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7700:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7701:       if(m != 1 && TKresult[nres]!= k1)
                   7702:        continue;
                   7703:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7704:        strcpy(gplotlabel,"(");      
                   7705:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7706:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7707:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7708:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7709:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7710:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7711:          vlv= nbcode[Tvaraff[k]][lv];
                   7712:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7713:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7714:        }
                   7715:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7716:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7717:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7718:        }       
                   7719:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7720:        fprintf(ficgp,"\n#\n");
                   7721:        if(invalidvarcomb[k1]){
                   7722:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7723:          continue;
                   7724:        }
                   7725:        
                   7726:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7727:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7728:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7729:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7730: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7731: 
                   7732:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7733:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7734:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7735:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7736:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7737:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7738:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7739:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7740:          if(i==istart){
                   7741:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7742:          }else{
                   7743:            fprintf(ficgp,",\\\n '' ");
                   7744:          }
                   7745:          if(cptcoveff ==0){ /* No covariate */
                   7746:            ioffset=2; /* Age is in 2 */
                   7747:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7748:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7749:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7750:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7751:            fprintf(ficgp," u %d:(", ioffset); 
                   7752:            if(i==nlstate+1){
1.270     brouard  7753:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7754:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7755:              fprintf(ficgp,",\\\n '' ");
                   7756:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7757:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7758:                     offbyear,                          \
                   7759:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7760:            }else
                   7761:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7762:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7763:          }else{ /* more than 2 covariates */
1.270     brouard  7764:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7765:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7766:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7767:            iyearc=ioffset-1;
                   7768:            iagec=ioffset;
1.268     brouard  7769:            fprintf(ficgp," u %d:(",ioffset); 
                   7770:            kl=0;
                   7771:            strcpy(gplotcondition,"(");
                   7772:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7773:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7774:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7775:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7776:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7777:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7778:              kl++;
                   7779:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7780:              kl++;
                   7781:              if(k <cptcoveff && cptcoveff>1)
                   7782:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7783:            }
                   7784:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7785:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7786:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7787:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7788:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7789:            if(i==nlstate+1){
1.270     brouard  7790:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7791:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7792:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7793:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7794:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7795:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7796:                      iyearc,iagec,offbyear,                            \
                   7797:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7798: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7799:            }else{
                   7800:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7801:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7802:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7803:            }
                   7804:          } /* end if covariate */
                   7805:        } /* nlstate */
                   7806:        fprintf(ficgp,"\nset out; unset label;\n");
                   7807:       } /* end cpt state*/
                   7808:     } /* end covariate */
                   7809:   } /* End if backcast */
                   7810:   
1.227     brouard  7811:   
1.238     brouard  7812:   /* 9eme writing MLE parameters */
                   7813:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7814:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7815:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7816:     for(k=1; k <=(nlstate+ndeath); k++){
                   7817:       if (k != i) {
1.227     brouard  7818:        fprintf(ficgp,"#   current state %d\n",k);
                   7819:        for(j=1; j <=ncovmodel; j++){
                   7820:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7821:          jk++; 
                   7822:        }
                   7823:        fprintf(ficgp,"\n");
1.126     brouard  7824:       }
                   7825:     }
1.223     brouard  7826:   }
1.187     brouard  7827:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7828:   
1.145     brouard  7829:   /*goto avoid;*/
1.238     brouard  7830:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7831:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7832:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7833:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7834:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7835:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7836:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7837:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7838:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7839:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7840:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7841:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7842:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7843:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7844:   fprintf(ficgp,"#\n");
1.223     brouard  7845:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7846:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7847:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7848:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7849:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7850:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7851:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7852:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7853:        continue;
1.264     brouard  7854:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7855:       strcpy(gplotlabel,"(");
1.276     brouard  7856:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7857:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7858:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7859:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7860:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7861:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7862:        vlv= nbcode[Tvaraff[k]][lv];
                   7863:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7864:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7865:       }
1.237     brouard  7866:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7867:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7868:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7869:       }        
1.264     brouard  7870:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7871:       fprintf(ficgp,"\n#\n");
1.264     brouard  7872:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7873:       fprintf(ficgp,"\nset key outside ");
                   7874:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7875:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7876:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7877:       if (ng==1){
                   7878:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7879:        fprintf(ficgp,"\nunset log y");
                   7880:       }else if (ng==2){
                   7881:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7882:        fprintf(ficgp,"\nset log y");
                   7883:       }else if (ng==3){
                   7884:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7885:        fprintf(ficgp,"\nset log y");
                   7886:       }else
                   7887:        fprintf(ficgp,"\nunset title ");
                   7888:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7889:       i=1;
                   7890:       for(k2=1; k2<=nlstate; k2++) {
                   7891:        k3=i;
                   7892:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7893:          if (k != k2){
                   7894:            switch( ng) {
                   7895:            case 1:
                   7896:              if(nagesqr==0)
                   7897:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7898:              else /* nagesqr =1 */
                   7899:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7900:              break;
                   7901:            case 2: /* ng=2 */
                   7902:              if(nagesqr==0)
                   7903:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7904:              else /* nagesqr =1 */
                   7905:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7906:              break;
                   7907:            case 3:
                   7908:              if(nagesqr==0)
                   7909:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7910:              else /* nagesqr =1 */
                   7911:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7912:              break;
                   7913:            }
                   7914:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7915:            ijp=1; /* product no age */
                   7916:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7917:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7918:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7919:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7920:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7921:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7922:                    if(DummyV[j]==0){
                   7923:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7924:                    }else{ /* quantitative */
                   7925:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7926:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7927:                    }
                   7928:                    ij++;
1.237     brouard  7929:                  }
1.268     brouard  7930:                } 
                   7931:              }else if(cptcovprod >0){
                   7932:                if(j==Tprod[ijp]) { /* */ 
                   7933:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7934:                  if(ijp <=cptcovprod) { /* Product */
                   7935:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7936:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7937:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7938:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7939:                      }else{ /* Vn is dummy and Vm is quanti */
                   7940:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7941:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7942:                      }
                   7943:                    }else{ /* Vn*Vm Vn is quanti */
                   7944:                      if(DummyV[Tvard[ijp][2]]==0){
                   7945:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7946:                      }else{ /* Both quanti */
                   7947:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7948:                      }
1.237     brouard  7949:                    }
1.268     brouard  7950:                    ijp++;
1.237     brouard  7951:                  }
1.268     brouard  7952:                } /* end Tprod */
1.237     brouard  7953:              } else{  /* simple covariate */
1.264     brouard  7954:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7955:                if(Dummy[j]==0){
                   7956:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7957:                }else{ /* quantitative */
                   7958:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7959:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7960:                }
1.237     brouard  7961:              } /* end simple */
                   7962:            } /* end j */
1.223     brouard  7963:          }else{
                   7964:            i=i-ncovmodel;
                   7965:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7966:              fprintf(ficgp," (1.");
                   7967:          }
1.227     brouard  7968:          
1.223     brouard  7969:          if(ng != 1){
                   7970:            fprintf(ficgp,")/(1");
1.227     brouard  7971:            
1.264     brouard  7972:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7973:              if(nagesqr==0)
1.264     brouard  7974:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7975:              else /* nagesqr =1 */
1.264     brouard  7976:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7977:               
1.223     brouard  7978:              ij=1;
                   7979:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7980:                 if(cptcovage >0){ 
                   7981:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7982:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7983:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7984:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7985:                       ij++;
                   7986:                     }
                   7987:                   }
                   7988:                 }else
                   7989:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7990:              }
                   7991:              fprintf(ficgp,")");
                   7992:            }
                   7993:            fprintf(ficgp,")");
                   7994:            if(ng ==2)
1.276     brouard  7995:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7996:            else /* ng= 3 */
1.276     brouard  7997:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  7998:          }else{ /* end ng <> 1 */
                   7999:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8000:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8001:          }
                   8002:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8003:            fprintf(ficgp,",");
                   8004:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8005:            fprintf(ficgp,",");
                   8006:          i=i+ncovmodel;
                   8007:        } /* end k */
                   8008:       } /* end k2 */
1.276     brouard  8009:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8010:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8011:     } /* end k1 */
1.223     brouard  8012:   } /* end ng */
                   8013:   /* avoid: */
                   8014:   fflush(ficgp); 
1.126     brouard  8015: }  /* end gnuplot */
                   8016: 
                   8017: 
                   8018: /*************** Moving average **************/
1.219     brouard  8019: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8020:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8021:    
1.222     brouard  8022:    int i, cpt, cptcod;
                   8023:    int modcovmax =1;
                   8024:    int mobilavrange, mob;
                   8025:    int iage=0;
                   8026: 
1.266     brouard  8027:    double sum=0., sumr=0.;
1.222     brouard  8028:    double age;
1.266     brouard  8029:    double *sumnewp, *sumnewm, *sumnewmr;
                   8030:    double *agemingood, *agemaxgood; 
                   8031:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8032:   
                   8033:   
1.278     brouard  8034:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8035:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8036: 
                   8037:    sumnewp = vector(1,ncovcombmax);
                   8038:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8039:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8040:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8041:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8042:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8043:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8044: 
                   8045:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8046:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8047:      sumnewp[cptcod]=0.;
1.266     brouard  8048:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8049:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8050:    }
                   8051:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8052:   
1.266     brouard  8053:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8054:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8055:      else mobilavrange=mobilav;
                   8056:      for (age=bage; age<=fage; age++)
                   8057:        for (i=1; i<=nlstate;i++)
                   8058:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8059:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8060:      /* We keep the original values on the extreme ages bage, fage and for 
                   8061:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8062:        we use a 5 terms etc. until the borders are no more concerned. 
                   8063:      */ 
                   8064:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8065:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8066:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8067:           sumnewm[cptcod]=0.;
                   8068:           for (i=1; i<=nlstate;i++){
1.222     brouard  8069:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8070:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8071:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8072:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8073:             }
                   8074:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8075:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8076:           } /* end i */
                   8077:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8078:         } /* end cptcod */
1.222     brouard  8079:        }/* end age */
                   8080:      }/* end mob */
1.266     brouard  8081:    }else{
                   8082:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8083:      return -1;
1.266     brouard  8084:    }
                   8085: 
                   8086:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8087:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8088:      if(invalidvarcomb[cptcod]){
                   8089:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8090:        continue;
                   8091:      }
1.219     brouard  8092: 
1.266     brouard  8093:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8094:        sumnewm[cptcod]=0.;
                   8095:        sumnewmr[cptcod]=0.;
                   8096:        for (i=1; i<=nlstate;i++){
                   8097:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8098:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8099:        }
                   8100:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8101:         agemingoodr[cptcod]=age;
                   8102:        }
                   8103:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8104:           agemingood[cptcod]=age;
                   8105:        }
                   8106:      } /* age */
                   8107:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8108:        sumnewm[cptcod]=0.;
1.266     brouard  8109:        sumnewmr[cptcod]=0.;
1.222     brouard  8110:        for (i=1; i<=nlstate;i++){
                   8111:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8112:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8113:        }
                   8114:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8115:         agemaxgoodr[cptcod]=age;
1.222     brouard  8116:        }
                   8117:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8118:         agemaxgood[cptcod]=age;
                   8119:        }
                   8120:      } /* age */
                   8121:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8122:      /* but they will change */
                   8123:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8124:        sumnewm[cptcod]=0.;
                   8125:        sumnewmr[cptcod]=0.;
                   8126:        for (i=1; i<=nlstate;i++){
                   8127:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8128:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8129:        }
                   8130:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8131:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8132:           agemaxgoodr[cptcod]=age;  /* age min */
                   8133:           for (i=1; i<=nlstate;i++)
                   8134:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8135:         }else{ /* bad we change the value with the values of good ages */
                   8136:           for (i=1; i<=nlstate;i++){
                   8137:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8138:           } /* i */
                   8139:         } /* end bad */
                   8140:        }else{
                   8141:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8142:           agemaxgood[cptcod]=age;
                   8143:         }else{ /* bad we change the value with the values of good ages */
                   8144:           for (i=1; i<=nlstate;i++){
                   8145:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8146:           } /* i */
                   8147:         } /* end bad */
                   8148:        }/* end else */
                   8149:        sum=0.;sumr=0.;
                   8150:        for (i=1; i<=nlstate;i++){
                   8151:         sum+=mobaverage[(int)age][i][cptcod];
                   8152:         sumr+=probs[(int)age][i][cptcod];
                   8153:        }
                   8154:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8155:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8156:        } /* end bad */
                   8157:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8158:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8159:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8160:        } /* end bad */
                   8161:      }/* age */
1.266     brouard  8162: 
                   8163:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8164:        sumnewm[cptcod]=0.;
1.266     brouard  8165:        sumnewmr[cptcod]=0.;
1.222     brouard  8166:        for (i=1; i<=nlstate;i++){
                   8167:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8168:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8169:        } 
                   8170:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8171:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8172:           agemingoodr[cptcod]=age;
                   8173:           for (i=1; i<=nlstate;i++)
                   8174:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8175:         }else{ /* bad we change the value with the values of good ages */
                   8176:           for (i=1; i<=nlstate;i++){
                   8177:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8178:           } /* i */
                   8179:         } /* end bad */
                   8180:        }else{
                   8181:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8182:           agemingood[cptcod]=age;
                   8183:         }else{ /* bad */
                   8184:           for (i=1; i<=nlstate;i++){
                   8185:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8186:           } /* i */
                   8187:         } /* end bad */
                   8188:        }/* end else */
                   8189:        sum=0.;sumr=0.;
                   8190:        for (i=1; i<=nlstate;i++){
                   8191:         sum+=mobaverage[(int)age][i][cptcod];
                   8192:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8193:        }
1.266     brouard  8194:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8195:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8196:        } /* end bad */
                   8197:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8198:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8199:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8200:        } /* end bad */
                   8201:      }/* age */
1.266     brouard  8202: 
1.222     brouard  8203:                
                   8204:      for (age=bage; age<=fage; age++){
1.235     brouard  8205:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8206:        sumnewp[cptcod]=0.;
                   8207:        sumnewm[cptcod]=0.;
                   8208:        for (i=1; i<=nlstate;i++){
                   8209:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8210:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8211:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8212:        }
                   8213:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8214:      }
                   8215:      /* printf("\n"); */
                   8216:      /* } */
1.266     brouard  8217: 
1.222     brouard  8218:      /* brutal averaging */
1.266     brouard  8219:      /* for (i=1; i<=nlstate;i++){ */
                   8220:      /*   for (age=1; age<=bage; age++){ */
                   8221:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8222:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8223:      /*   }     */
                   8224:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8225:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8226:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8227:      /*   } */
                   8228:      /* } /\* end i status *\/ */
                   8229:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8230:      /*   for (age=1; age<=AGESUP; age++){ */
                   8231:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8232:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8233:      /*   } */
                   8234:      /* } */
1.222     brouard  8235:    }/* end cptcod */
1.266     brouard  8236:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8237:    free_vector(agemaxgood,1, ncovcombmax);
                   8238:    free_vector(agemingood,1, ncovcombmax);
                   8239:    free_vector(agemingoodr,1, ncovcombmax);
                   8240:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8241:    free_vector(sumnewm,1, ncovcombmax);
                   8242:    free_vector(sumnewp,1, ncovcombmax);
                   8243:    return 0;
                   8244:  }/* End movingaverage */
1.218     brouard  8245:  
1.126     brouard  8246: 
                   8247: /************** Forecasting ******************/
1.269     brouard  8248:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8249:   /* proj1, year, month, day of starting projection 
                   8250:      agemin, agemax range of age
                   8251:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8252:      anproj2 year of en of projection (same day and month as proj1).
                   8253:   */
1.267     brouard  8254:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8255:   double agec; /* generic age */
                   8256:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8257:   double *popeffectif,*popcount;
                   8258:   double ***p3mat;
1.218     brouard  8259:   /* double ***mobaverage; */
1.126     brouard  8260:   char fileresf[FILENAMELENGTH];
                   8261: 
                   8262:   agelim=AGESUP;
1.211     brouard  8263:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8264:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8265:      We still use firstpass and lastpass as another selection.
                   8266:   */
1.214     brouard  8267:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8268:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8269:  
1.201     brouard  8270:   strcpy(fileresf,"F_"); 
                   8271:   strcat(fileresf,fileresu);
1.126     brouard  8272:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8273:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8274:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8275:   }
1.235     brouard  8276:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8277:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8278: 
1.225     brouard  8279:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8280: 
                   8281: 
                   8282:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8283:   if (stepm<=12) stepsize=1;
                   8284:   if(estepm < stepm){
                   8285:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8286:   }
1.270     brouard  8287:   else{
                   8288:     hstepm=estepm;   
                   8289:   }
                   8290:   if(estepm > stepm){ /* Yes every two year */
                   8291:     stepsize=2;
                   8292:   }
1.126     brouard  8293: 
                   8294:   hstepm=hstepm/stepm; 
                   8295:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8296:                                fractional in yp1 */
                   8297:   anprojmean=yp;
                   8298:   yp2=modf((yp1*12),&yp);
                   8299:   mprojmean=yp;
                   8300:   yp1=modf((yp2*30.5),&yp);
                   8301:   jprojmean=yp;
                   8302:   if(jprojmean==0) jprojmean=1;
                   8303:   if(mprojmean==0) jprojmean=1;
                   8304: 
1.227     brouard  8305:   i1=pow(2,cptcoveff);
1.126     brouard  8306:   if (cptcovn < 1){i1=1;}
                   8307:   
                   8308:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8309:   
                   8310:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8311:   
1.126     brouard  8312: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8313:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8314:   for(k=1; k<=i1;k++){
1.253     brouard  8315:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8316:       continue;
1.227     brouard  8317:     if(invalidvarcomb[k]){
                   8318:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8319:       continue;
                   8320:     }
                   8321:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8322:     for(j=1;j<=cptcoveff;j++) {
                   8323:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8324:     }
1.235     brouard  8325:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8326:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8327:     }
1.227     brouard  8328:     fprintf(ficresf," yearproj age");
                   8329:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8330:       for(i=1; i<=nlstate;i++)               
                   8331:        fprintf(ficresf," p%d%d",i,j);
                   8332:       fprintf(ficresf," wp.%d",j);
                   8333:     }
                   8334:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8335:       fprintf(ficresf,"\n");
                   8336:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8337:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8338:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8339:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8340:        nhstepm = nhstepm/hstepm; 
                   8341:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8342:        oldm=oldms;savm=savms;
1.268     brouard  8343:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8344:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8345:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8346:        for (h=0; h<=nhstepm; h++){
                   8347:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8348:            break;
                   8349:          }
                   8350:        }
                   8351:        fprintf(ficresf,"\n");
                   8352:        for(j=1;j<=cptcoveff;j++) 
                   8353:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8354:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8355:        
                   8356:        for(j=1; j<=nlstate+ndeath;j++) {
                   8357:          ppij=0.;
                   8358:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8359:            if (mobilav>=1)
                   8360:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8361:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8362:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8363:            }
1.268     brouard  8364:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8365:          } /* end i */
                   8366:          fprintf(ficresf," %.3f", ppij);
                   8367:        }/* end j */
1.227     brouard  8368:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8369:       } /* end agec */
1.266     brouard  8370:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8371:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8372:     } /* end yearp */
                   8373:   } /* end  k */
1.219     brouard  8374:        
1.126     brouard  8375:   fclose(ficresf);
1.215     brouard  8376:   printf("End of Computing forecasting \n");
                   8377:   fprintf(ficlog,"End of Computing forecasting\n");
                   8378: 
1.126     brouard  8379: }
                   8380: 
1.269     brouard  8381: /************** Back Forecasting ******************/
                   8382:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8383:   /* back1, year, month, day of starting backection
                   8384:      agemin, agemax range of age
                   8385:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8386:      anback2 year of end of backprojection (same day and month as back1).
                   8387:      prevacurrent and prev are prevalences.
1.267     brouard  8388:   */
                   8389:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8390:   double agec; /* generic age */
1.268     brouard  8391:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8392:   double *popeffectif,*popcount;
                   8393:   double ***p3mat;
                   8394:   /* double ***mobaverage; */
                   8395:   char fileresfb[FILENAMELENGTH];
                   8396:  
1.268     brouard  8397:   agelim=AGEINF;
1.267     brouard  8398:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8399:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8400:      We still use firstpass and lastpass as another selection.
                   8401:   */
                   8402:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8403:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8404: 
                   8405:   /*Do we need to compute prevalence again?*/
                   8406: 
                   8407:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8408:   
                   8409:   strcpy(fileresfb,"FB_");
                   8410:   strcat(fileresfb,fileresu);
                   8411:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8412:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8413:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8414:   }
                   8415:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8416:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8417:   
                   8418:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8419:   
                   8420:    
                   8421:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8422:   if (stepm<=12) stepsize=1;
                   8423:   if(estepm < stepm){
                   8424:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8425:   }
1.270     brouard  8426:   else{
                   8427:     hstepm=estepm;   
                   8428:   }
                   8429:   if(estepm >= stepm){ /* Yes every two year */
                   8430:     stepsize=2;
                   8431:   }
1.267     brouard  8432:   
                   8433:   hstepm=hstepm/stepm;
                   8434:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8435:                                fractional in yp1 */
                   8436:   anprojmean=yp;
                   8437:   yp2=modf((yp1*12),&yp);
                   8438:   mprojmean=yp;
                   8439:   yp1=modf((yp2*30.5),&yp);
                   8440:   jprojmean=yp;
                   8441:   if(jprojmean==0) jprojmean=1;
                   8442:   if(mprojmean==0) jprojmean=1;
                   8443:   
                   8444:   i1=pow(2,cptcoveff);
                   8445:   if (cptcovn < 1){i1=1;}
                   8446:   
                   8447:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8448:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8449:   
                   8450:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8451:   
                   8452:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8453:   for(k=1; k<=i1;k++){
                   8454:     if(i1 != 1 && TKresult[nres]!= k)
                   8455:       continue;
                   8456:     if(invalidvarcomb[k]){
                   8457:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8458:       continue;
                   8459:     }
1.268     brouard  8460:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8461:     for(j=1;j<=cptcoveff;j++) {
                   8462:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8463:     }
                   8464:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8465:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8466:     }
                   8467:     fprintf(ficresfb," yearbproj age");
                   8468:     for(j=1; j<=nlstate+ndeath;j++){
                   8469:       for(i=1; i<=nlstate;i++)
1.268     brouard  8470:        fprintf(ficresfb," b%d%d",i,j);
                   8471:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8472:     }
                   8473:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8474:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8475:       fprintf(ficresfb,"\n");
                   8476:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8477:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8478:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8479:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8480:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8481:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8482:        nhstepm = nhstepm/hstepm;
                   8483:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8484:        oldm=oldms;savm=savms;
1.268     brouard  8485:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8486:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8487:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8488:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8489:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8490:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8491:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8492:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8493:            break;
                   8494:          }
                   8495:        }
                   8496:        fprintf(ficresfb,"\n");
                   8497:        for(j=1;j<=cptcoveff;j++)
                   8498:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8499:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8500:        for(i=1; i<=nlstate+ndeath;i++) {
                   8501:          ppij=0.;ppi=0.;
                   8502:          for(j=1; j<=nlstate;j++) {
                   8503:            /* if (mobilav==1) */
1.269     brouard  8504:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8505:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8506:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8507:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8508:              /* else { */
                   8509:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8510:              /* } */
1.268     brouard  8511:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8512:          } /* end j */
                   8513:          if(ppi <0.99){
                   8514:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8515:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8516:          }
                   8517:          fprintf(ficresfb," %.3f", ppij);
                   8518:        }/* end j */
1.267     brouard  8519:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8520:       } /* end agec */
                   8521:     } /* end yearp */
                   8522:   } /* end k */
1.217     brouard  8523:   
1.267     brouard  8524:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8525:   
1.267     brouard  8526:   fclose(ficresfb);
                   8527:   printf("End of Computing Back forecasting \n");
                   8528:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8529:        
1.267     brouard  8530: }
1.217     brouard  8531: 
1.269     brouard  8532: /* Variance of prevalence limit: varprlim */
                   8533:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8534:     /*------- Variance of period (stable) prevalence------*/   
                   8535:  
                   8536:    char fileresvpl[FILENAMELENGTH];  
                   8537:    FILE *ficresvpl;
                   8538:    double **oldm, **savm;
                   8539:    double **varpl; /* Variances of prevalence limits by age */   
                   8540:    int i1, k, nres, j ;
                   8541:    
                   8542:     strcpy(fileresvpl,"VPL_");
                   8543:     strcat(fileresvpl,fileresu);
                   8544:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8545:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8546:       exit(0);
                   8547:     }
                   8548:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8549:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8550:     
                   8551:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8552:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8553:     
                   8554:     i1=pow(2,cptcoveff);
                   8555:     if (cptcovn < 1){i1=1;}
                   8556: 
                   8557:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8558:     for(k=1; k<=i1;k++){
                   8559:       if(i1 != 1 && TKresult[nres]!= k)
                   8560:        continue;
                   8561:       fprintf(ficresvpl,"\n#****** ");
                   8562:       printf("\n#****** ");
                   8563:       fprintf(ficlog,"\n#****** ");
                   8564:       for(j=1;j<=cptcoveff;j++) {
                   8565:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8566:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8567:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8568:       }
                   8569:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8570:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8571:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8572:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8573:       }        
                   8574:       fprintf(ficresvpl,"******\n");
                   8575:       printf("******\n");
                   8576:       fprintf(ficlog,"******\n");
                   8577:       
                   8578:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8579:       oldm=oldms;savm=savms;
                   8580:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8581:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8582:       /*}*/
                   8583:     }
                   8584:     
                   8585:     fclose(ficresvpl);
                   8586:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8587:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8588: 
                   8589:  }
                   8590: /* Variance of back prevalence: varbprlim */
                   8591:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8592:       /*------- Variance of back (stable) prevalence------*/
                   8593: 
                   8594:    char fileresvbl[FILENAMELENGTH];  
                   8595:    FILE  *ficresvbl;
                   8596: 
                   8597:    double **oldm, **savm;
                   8598:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8599:    int i1, k, nres, j ;
                   8600: 
                   8601:    strcpy(fileresvbl,"VBL_");
                   8602:    strcat(fileresvbl,fileresu);
                   8603:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8604:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8605:      exit(0);
                   8606:    }
                   8607:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8608:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8609:    
                   8610:    
                   8611:    i1=pow(2,cptcoveff);
                   8612:    if (cptcovn < 1){i1=1;}
                   8613:    
                   8614:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8615:      for(k=1; k<=i1;k++){
                   8616:        if(i1 != 1 && TKresult[nres]!= k)
                   8617:         continue;
                   8618:        fprintf(ficresvbl,"\n#****** ");
                   8619:        printf("\n#****** ");
                   8620:        fprintf(ficlog,"\n#****** ");
                   8621:        for(j=1;j<=cptcoveff;j++) {
                   8622:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8623:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8624:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8625:        }
                   8626:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8627:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8628:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8629:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8630:        }
                   8631:        fprintf(ficresvbl,"******\n");
                   8632:        printf("******\n");
                   8633:        fprintf(ficlog,"******\n");
                   8634:        
                   8635:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8636:        oldm=oldms;savm=savms;
                   8637:        
                   8638:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8639:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8640:        /*}*/
                   8641:      }
                   8642:    
                   8643:    fclose(ficresvbl);
                   8644:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8645:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8646: 
                   8647:  } /* End of varbprlim */
                   8648: 
1.126     brouard  8649: /************** Forecasting *****not tested NB*************/
1.227     brouard  8650: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8651:   
1.227     brouard  8652: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8653: /*   int *popage; */
                   8654: /*   double calagedatem, agelim, kk1, kk2; */
                   8655: /*   double *popeffectif,*popcount; */
                   8656: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8657: /*   /\* double ***mobaverage; *\/ */
                   8658: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8659: 
1.227     brouard  8660: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8661: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8662: /*   agelim=AGESUP; */
                   8663: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8664:   
1.227     brouard  8665: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8666:   
                   8667:   
1.227     brouard  8668: /*   strcpy(filerespop,"POP_");  */
                   8669: /*   strcat(filerespop,fileresu); */
                   8670: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8671: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8672: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8673: /*   } */
                   8674: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8675: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8676: 
1.227     brouard  8677: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8678: 
1.227     brouard  8679: /*   /\* if (mobilav!=0) { *\/ */
                   8680: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8681: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8682: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8683: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8684: /*   /\*   } *\/ */
                   8685: /*   /\* } *\/ */
1.126     brouard  8686: 
1.227     brouard  8687: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8688: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8689:   
1.227     brouard  8690: /*   agelim=AGESUP; */
1.126     brouard  8691:   
1.227     brouard  8692: /*   hstepm=1; */
                   8693: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8694:        
1.227     brouard  8695: /*   if (popforecast==1) { */
                   8696: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8697: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8698: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8699: /*     }  */
                   8700: /*     popage=ivector(0,AGESUP); */
                   8701: /*     popeffectif=vector(0,AGESUP); */
                   8702: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8703:     
1.227     brouard  8704: /*     i=1;    */
                   8705: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8706:     
1.227     brouard  8707: /*     imx=i; */
                   8708: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8709: /*   } */
1.218     brouard  8710:   
1.227     brouard  8711: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8712: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8713: /*       k=k+1; */
                   8714: /*       fprintf(ficrespop,"\n#******"); */
                   8715: /*       for(j=1;j<=cptcoveff;j++) { */
                   8716: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8717: /*       } */
                   8718: /*       fprintf(ficrespop,"******\n"); */
                   8719: /*       fprintf(ficrespop,"# Age"); */
                   8720: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8721: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8722:       
1.227     brouard  8723: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8724: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8725:        
1.227     brouard  8726: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8727: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8728: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8729:          
1.227     brouard  8730: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8731: /*       oldm=oldms;savm=savms; */
                   8732: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8733:          
1.227     brouard  8734: /*       for (h=0; h<=nhstepm; h++){ */
                   8735: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8736: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8737: /*         }  */
                   8738: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8739: /*           kk1=0.;kk2=0; */
                   8740: /*           for(i=1; i<=nlstate;i++) {               */
                   8741: /*             if (mobilav==1)  */
                   8742: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8743: /*             else { */
                   8744: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8745: /*             } */
                   8746: /*           } */
                   8747: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8748: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8749: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8750: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8751: /*           } */
                   8752: /*         } */
                   8753: /*         for(i=1; i<=nlstate;i++){ */
                   8754: /*           kk1=0.; */
                   8755: /*           for(j=1; j<=nlstate;j++){ */
                   8756: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8757: /*           } */
                   8758: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8759: /*         } */
1.218     brouard  8760:            
1.227     brouard  8761: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8762: /*           for(j=1; j<=nlstate;j++)  */
                   8763: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8764: /*       } */
                   8765: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8766: /*     } */
                   8767: /*       } */
1.218     brouard  8768:       
1.227     brouard  8769: /*       /\******\/ */
1.218     brouard  8770:       
1.227     brouard  8771: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8772: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8773: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8774: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8775: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8776:          
1.227     brouard  8777: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8778: /*       oldm=oldms;savm=savms; */
                   8779: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8780: /*       for (h=0; h<=nhstepm; h++){ */
                   8781: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8782: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8783: /*         }  */
                   8784: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8785: /*           kk1=0.;kk2=0; */
                   8786: /*           for(i=1; i<=nlstate;i++) {               */
                   8787: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8788: /*           } */
                   8789: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8790: /*         } */
                   8791: /*       } */
                   8792: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8793: /*     } */
                   8794: /*       } */
                   8795: /*     }  */
                   8796: /*   } */
1.218     brouard  8797:   
1.227     brouard  8798: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8799:   
1.227     brouard  8800: /*   if (popforecast==1) { */
                   8801: /*     free_ivector(popage,0,AGESUP); */
                   8802: /*     free_vector(popeffectif,0,AGESUP); */
                   8803: /*     free_vector(popcount,0,AGESUP); */
                   8804: /*   } */
                   8805: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8806: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8807: /*   fclose(ficrespop); */
                   8808: /* } /\* End of popforecast *\/ */
1.218     brouard  8809:  
1.126     brouard  8810: int fileappend(FILE *fichier, char *optionfich)
                   8811: {
                   8812:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8813:     printf("Problem with file: %s\n", optionfich);
                   8814:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8815:     return (0);
                   8816:   }
                   8817:   fflush(fichier);
                   8818:   return (1);
                   8819: }
                   8820: 
                   8821: 
                   8822: /**************** function prwizard **********************/
                   8823: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8824: {
                   8825: 
                   8826:   /* Wizard to print covariance matrix template */
                   8827: 
1.164     brouard  8828:   char ca[32], cb[32];
                   8829:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8830:   int numlinepar;
                   8831: 
                   8832:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8833:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8834:   for(i=1; i <=nlstate; i++){
                   8835:     jj=0;
                   8836:     for(j=1; j <=nlstate+ndeath; j++){
                   8837:       if(j==i) continue;
                   8838:       jj++;
                   8839:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8840:       printf("%1d%1d",i,j);
                   8841:       fprintf(ficparo,"%1d%1d",i,j);
                   8842:       for(k=1; k<=ncovmodel;k++){
                   8843:        /*        printf(" %lf",param[i][j][k]); */
                   8844:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8845:        printf(" 0.");
                   8846:        fprintf(ficparo," 0.");
                   8847:       }
                   8848:       printf("\n");
                   8849:       fprintf(ficparo,"\n");
                   8850:     }
                   8851:   }
                   8852:   printf("# Scales (for hessian or gradient estimation)\n");
                   8853:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8854:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8855:   for(i=1; i <=nlstate; i++){
                   8856:     jj=0;
                   8857:     for(j=1; j <=nlstate+ndeath; j++){
                   8858:       if(j==i) continue;
                   8859:       jj++;
                   8860:       fprintf(ficparo,"%1d%1d",i,j);
                   8861:       printf("%1d%1d",i,j);
                   8862:       fflush(stdout);
                   8863:       for(k=1; k<=ncovmodel;k++){
                   8864:        /*      printf(" %le",delti3[i][j][k]); */
                   8865:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8866:        printf(" 0.");
                   8867:        fprintf(ficparo," 0.");
                   8868:       }
                   8869:       numlinepar++;
                   8870:       printf("\n");
                   8871:       fprintf(ficparo,"\n");
                   8872:     }
                   8873:   }
                   8874:   printf("# Covariance matrix\n");
                   8875: /* # 121 Var(a12)\n\ */
                   8876: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8877: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8878: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8879: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8880: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8881: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8882: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8883:   fflush(stdout);
                   8884:   fprintf(ficparo,"# Covariance matrix\n");
                   8885:   /* # 121 Var(a12)\n\ */
                   8886:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8887:   /* #   ...\n\ */
                   8888:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8889:   
                   8890:   for(itimes=1;itimes<=2;itimes++){
                   8891:     jj=0;
                   8892:     for(i=1; i <=nlstate; i++){
                   8893:       for(j=1; j <=nlstate+ndeath; j++){
                   8894:        if(j==i) continue;
                   8895:        for(k=1; k<=ncovmodel;k++){
                   8896:          jj++;
                   8897:          ca[0]= k+'a'-1;ca[1]='\0';
                   8898:          if(itimes==1){
                   8899:            printf("#%1d%1d%d",i,j,k);
                   8900:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8901:          }else{
                   8902:            printf("%1d%1d%d",i,j,k);
                   8903:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8904:            /*  printf(" %.5le",matcov[i][j]); */
                   8905:          }
                   8906:          ll=0;
                   8907:          for(li=1;li <=nlstate; li++){
                   8908:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8909:              if(lj==li) continue;
                   8910:              for(lk=1;lk<=ncovmodel;lk++){
                   8911:                ll++;
                   8912:                if(ll<=jj){
                   8913:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8914:                  if(ll<jj){
                   8915:                    if(itimes==1){
                   8916:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8917:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8918:                    }else{
                   8919:                      printf(" 0.");
                   8920:                      fprintf(ficparo," 0.");
                   8921:                    }
                   8922:                  }else{
                   8923:                    if(itimes==1){
                   8924:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8925:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8926:                    }else{
                   8927:                      printf(" 0.");
                   8928:                      fprintf(ficparo," 0.");
                   8929:                    }
                   8930:                  }
                   8931:                }
                   8932:              } /* end lk */
                   8933:            } /* end lj */
                   8934:          } /* end li */
                   8935:          printf("\n");
                   8936:          fprintf(ficparo,"\n");
                   8937:          numlinepar++;
                   8938:        } /* end k*/
                   8939:       } /*end j */
                   8940:     } /* end i */
                   8941:   } /* end itimes */
                   8942: 
                   8943: } /* end of prwizard */
                   8944: /******************* Gompertz Likelihood ******************************/
                   8945: double gompertz(double x[])
                   8946: { 
                   8947:   double A,B,L=0.0,sump=0.,num=0.;
                   8948:   int i,n=0; /* n is the size of the sample */
                   8949: 
1.220     brouard  8950:   for (i=1;i<=imx ; i++) {
1.126     brouard  8951:     sump=sump+weight[i];
                   8952:     /*    sump=sump+1;*/
                   8953:     num=num+1;
                   8954:   }
                   8955:  
                   8956:  
                   8957:   /* for (i=0; i<=imx; i++) 
                   8958:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8959: 
                   8960:   for (i=1;i<=imx ; i++)
                   8961:     {
                   8962:       if (cens[i] == 1 && wav[i]>1)
                   8963:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8964:       
                   8965:       if (cens[i] == 0 && wav[i]>1)
                   8966:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8967:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8968:       
                   8969:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8970:       if (wav[i] > 1 ) { /* ??? */
                   8971:        L=L+A*weight[i];
                   8972:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8973:       }
                   8974:     }
                   8975: 
                   8976:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8977:  
                   8978:   return -2*L*num/sump;
                   8979: }
                   8980: 
1.136     brouard  8981: #ifdef GSL
                   8982: /******************* Gompertz_f Likelihood ******************************/
                   8983: double gompertz_f(const gsl_vector *v, void *params)
                   8984: { 
                   8985:   double A,B,LL=0.0,sump=0.,num=0.;
                   8986:   double *x= (double *) v->data;
                   8987:   int i,n=0; /* n is the size of the sample */
                   8988: 
                   8989:   for (i=0;i<=imx-1 ; i++) {
                   8990:     sump=sump+weight[i];
                   8991:     /*    sump=sump+1;*/
                   8992:     num=num+1;
                   8993:   }
                   8994:  
                   8995:  
                   8996:   /* for (i=0; i<=imx; i++) 
                   8997:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8998:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8999:   for (i=1;i<=imx ; i++)
                   9000:     {
                   9001:       if (cens[i] == 1 && wav[i]>1)
                   9002:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9003:       
                   9004:       if (cens[i] == 0 && wav[i]>1)
                   9005:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9006:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9007:       
                   9008:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9009:       if (wav[i] > 1 ) { /* ??? */
                   9010:        LL=LL+A*weight[i];
                   9011:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9012:       }
                   9013:     }
                   9014: 
                   9015:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9016:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9017:  
                   9018:   return -2*LL*num/sump;
                   9019: }
                   9020: #endif
                   9021: 
1.126     brouard  9022: /******************* Printing html file ***********/
1.201     brouard  9023: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9024:                  int lastpass, int stepm, int weightopt, char model[],\
                   9025:                  int imx,  double p[],double **matcov,double agemortsup){
                   9026:   int i,k;
                   9027: 
                   9028:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9029:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9030:   for (i=1;i<=2;i++) 
                   9031:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9032:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9033:   fprintf(fichtm,"</ul>");
                   9034: 
                   9035: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9036: 
                   9037:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9038: 
                   9039:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9040:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9041: 
                   9042:  
                   9043:   fflush(fichtm);
                   9044: }
                   9045: 
                   9046: /******************* Gnuplot file **************/
1.201     brouard  9047: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9048: 
                   9049:   char dirfileres[132],optfileres[132];
1.164     brouard  9050: 
1.126     brouard  9051:   int ng;
                   9052: 
                   9053: 
                   9054:   /*#ifdef windows */
                   9055:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9056:     /*#endif */
                   9057: 
                   9058: 
                   9059:   strcpy(dirfileres,optionfilefiname);
                   9060:   strcpy(optfileres,"vpl");
1.199     brouard  9061:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9062:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9063:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9064:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9065:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9066: 
                   9067: } 
                   9068: 
1.136     brouard  9069: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9070: {
1.126     brouard  9071: 
1.136     brouard  9072:   /*-------- data file ----------*/
                   9073:   FILE *fic;
                   9074:   char dummy[]="                         ";
1.240     brouard  9075:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9076:   int lstra;
1.136     brouard  9077:   int linei, month, year,iout;
                   9078:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9079:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9080:   char *stratrunc;
1.223     brouard  9081: 
1.240     brouard  9082:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9083:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9084: 
1.240     brouard  9085:   for(v=1; v <=ncovcol;v++){
                   9086:     DummyV[v]=0;
                   9087:     FixedV[v]=0;
                   9088:   }
                   9089:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9090:     DummyV[v]=1;
                   9091:     FixedV[v]=0;
                   9092:   }
                   9093:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9094:     DummyV[v]=0;
                   9095:     FixedV[v]=1;
                   9096:   }
                   9097:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9098:     DummyV[v]=1;
                   9099:     FixedV[v]=1;
                   9100:   }
                   9101:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9102:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9103:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9104:   }
1.126     brouard  9105: 
1.136     brouard  9106:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9107:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9108:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9109:   }
1.126     brouard  9110: 
1.136     brouard  9111:   i=1;
                   9112:   linei=0;
                   9113:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9114:     linei=linei+1;
                   9115:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9116:       if(line[j] == '\t')
                   9117:        line[j] = ' ';
                   9118:     }
                   9119:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9120:       ;
                   9121:     };
                   9122:     line[j+1]=0;  /* Trims blanks at end of line */
                   9123:     if(line[0]=='#'){
                   9124:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9125:       printf("Comment line\n%s\n",line);
                   9126:       continue;
                   9127:     }
                   9128:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9129:     strcpy(line, linetmp);
1.223     brouard  9130:     
                   9131:     /* Loops on waves */
                   9132:     for (j=maxwav;j>=1;j--){
                   9133:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9134:        cutv(stra, strb, line, ' '); 
                   9135:        if(strb[0]=='.') { /* Missing value */
                   9136:          lval=-1;
                   9137:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9138:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9139:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9140:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9141:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9142:            return 1;
                   9143:          }
                   9144:        }else{
                   9145:          errno=0;
                   9146:          /* what_kind_of_number(strb); */
                   9147:          dval=strtod(strb,&endptr); 
                   9148:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9149:          /* if(strb != endptr && *endptr == '\0') */
                   9150:          /*    dval=dlval; */
                   9151:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9152:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9153:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9154:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9155:            return 1;
                   9156:          }
                   9157:          cotqvar[j][iv][i]=dval; 
                   9158:          cotvar[j][ntv+iv][i]=dval; 
                   9159:        }
                   9160:        strcpy(line,stra);
1.223     brouard  9161:       }/* end loop ntqv */
1.225     brouard  9162:       
1.223     brouard  9163:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9164:        cutv(stra, strb, line, ' '); 
                   9165:        if(strb[0]=='.') { /* Missing value */
                   9166:          lval=-1;
                   9167:        }else{
                   9168:          errno=0;
                   9169:          lval=strtol(strb,&endptr,10); 
                   9170:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9171:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9172:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9173:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9174:            return 1;
                   9175:          }
                   9176:        }
                   9177:        if(lval <-1 || lval >1){
                   9178:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9179:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9180:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9181:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9182:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9183:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9184:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9185:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9186:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9187:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9188:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9189:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9190:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9191:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9192:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9193:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9194:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9195:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9196:          return 1;
                   9197:        }
                   9198:        cotvar[j][iv][i]=(double)(lval);
                   9199:        strcpy(line,stra);
1.223     brouard  9200:       }/* end loop ntv */
1.225     brouard  9201:       
1.223     brouard  9202:       /* Statuses  at wave */
1.137     brouard  9203:       cutv(stra, strb, line, ' '); 
1.223     brouard  9204:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9205:        lval=-1;
1.136     brouard  9206:       }else{
1.238     brouard  9207:        errno=0;
                   9208:        lval=strtol(strb,&endptr,10); 
                   9209:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9210:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9211:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9212:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9213:          return 1;
                   9214:        }
1.136     brouard  9215:       }
1.225     brouard  9216:       
1.136     brouard  9217:       s[j][i]=lval;
1.225     brouard  9218:       
1.223     brouard  9219:       /* Date of Interview */
1.136     brouard  9220:       strcpy(line,stra);
                   9221:       cutv(stra, strb,line,' ');
1.169     brouard  9222:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9223:       }
1.169     brouard  9224:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9225:        month=99;
                   9226:        year=9999;
1.136     brouard  9227:       }else{
1.225     brouard  9228:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9229:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9230:        return 1;
1.136     brouard  9231:       }
                   9232:       anint[j][i]= (double) year; 
                   9233:       mint[j][i]= (double)month; 
                   9234:       strcpy(line,stra);
1.223     brouard  9235:     } /* End loop on waves */
1.225     brouard  9236:     
1.223     brouard  9237:     /* Date of death */
1.136     brouard  9238:     cutv(stra, strb,line,' '); 
1.169     brouard  9239:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9240:     }
1.169     brouard  9241:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9242:       month=99;
                   9243:       year=9999;
                   9244:     }else{
1.141     brouard  9245:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9246:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9247:       return 1;
1.136     brouard  9248:     }
                   9249:     andc[i]=(double) year; 
                   9250:     moisdc[i]=(double) month; 
                   9251:     strcpy(line,stra);
                   9252:     
1.223     brouard  9253:     /* Date of birth */
1.136     brouard  9254:     cutv(stra, strb,line,' '); 
1.169     brouard  9255:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9256:     }
1.169     brouard  9257:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9258:       month=99;
                   9259:       year=9999;
                   9260:     }else{
1.141     brouard  9261:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9262:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9263:       return 1;
1.136     brouard  9264:     }
                   9265:     if (year==9999) {
1.141     brouard  9266:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9267:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9268:       return 1;
                   9269:       
1.136     brouard  9270:     }
                   9271:     annais[i]=(double)(year);
                   9272:     moisnais[i]=(double)(month); 
                   9273:     strcpy(line,stra);
1.225     brouard  9274:     
1.223     brouard  9275:     /* Sample weight */
1.136     brouard  9276:     cutv(stra, strb,line,' '); 
                   9277:     errno=0;
                   9278:     dval=strtod(strb,&endptr); 
                   9279:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9280:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9281:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9282:       fflush(ficlog);
                   9283:       return 1;
                   9284:     }
                   9285:     weight[i]=dval; 
                   9286:     strcpy(line,stra);
1.225     brouard  9287:     
1.223     brouard  9288:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9289:       cutv(stra, strb, line, ' '); 
                   9290:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9291:        lval=-1;
1.223     brouard  9292:       }else{
1.225     brouard  9293:        errno=0;
                   9294:        /* what_kind_of_number(strb); */
                   9295:        dval=strtod(strb,&endptr);
                   9296:        /* if(strb != endptr && *endptr == '\0') */
                   9297:        /*   dval=dlval; */
                   9298:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9299:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9300:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9301:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9302:          return 1;
                   9303:        }
                   9304:        coqvar[iv][i]=dval; 
1.226     brouard  9305:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9306:       }
                   9307:       strcpy(line,stra);
                   9308:     }/* end loop nqv */
1.136     brouard  9309:     
1.223     brouard  9310:     /* Covariate values */
1.136     brouard  9311:     for (j=ncovcol;j>=1;j--){
                   9312:       cutv(stra, strb,line,' '); 
1.223     brouard  9313:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9314:        lval=-1;
1.136     brouard  9315:       }else{
1.225     brouard  9316:        errno=0;
                   9317:        lval=strtol(strb,&endptr,10); 
                   9318:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9319:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9320:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9321:          return 1;
                   9322:        }
1.136     brouard  9323:       }
                   9324:       if(lval <-1 || lval >1){
1.225     brouard  9325:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9326:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9327:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9328:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9329:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9330:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9331:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9332:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9333:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9334:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9335:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9336:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9337:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9338:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9339:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9340:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9341:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9342:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9343:        return 1;
1.136     brouard  9344:       }
                   9345:       covar[j][i]=(double)(lval);
                   9346:       strcpy(line,stra);
                   9347:     }  
                   9348:     lstra=strlen(stra);
1.225     brouard  9349:     
1.136     brouard  9350:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9351:       stratrunc = &(stra[lstra-9]);
                   9352:       num[i]=atol(stratrunc);
                   9353:     }
                   9354:     else
                   9355:       num[i]=atol(stra);
                   9356:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9357:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9358:     
                   9359:     i=i+1;
                   9360:   } /* End loop reading  data */
1.225     brouard  9361:   
1.136     brouard  9362:   *imax=i-1; /* Number of individuals */
                   9363:   fclose(fic);
1.225     brouard  9364:   
1.136     brouard  9365:   return (0);
1.164     brouard  9366:   /* endread: */
1.225     brouard  9367:   printf("Exiting readdata: ");
                   9368:   fclose(fic);
                   9369:   return (1);
1.223     brouard  9370: }
1.126     brouard  9371: 
1.234     brouard  9372: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9373:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9374:   while (*p2 == ' ')
1.234     brouard  9375:     p2++; 
                   9376:   /* while ((*p1++ = *p2++) !=0) */
                   9377:   /*   ; */
                   9378:   /* do */
                   9379:   /*   while (*p2 == ' ') */
                   9380:   /*     p2++; */
                   9381:   /* while (*p1++ == *p2++); */
                   9382:   *stri=p2; 
1.145     brouard  9383: }
                   9384: 
1.235     brouard  9385: int decoderesult ( char resultline[], int nres)
1.230     brouard  9386: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9387: {
1.235     brouard  9388:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9389:   char resultsav[MAXLINE];
1.234     brouard  9390:   int resultmodel[MAXLINE];
                   9391:   int modelresult[MAXLINE];
1.230     brouard  9392:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9393: 
1.234     brouard  9394:   removefirstspace(&resultline);
1.233     brouard  9395:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9396: 
                   9397:   if (strstr(resultline,"v") !=0){
                   9398:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9399:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9400:     return 1;
                   9401:   }
                   9402:   trimbb(resultsav, resultline);
                   9403:   if (strlen(resultsav) >1){
                   9404:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9405:   }
1.253     brouard  9406:   if(j == 0){ /* Resultline but no = */
                   9407:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9408:     return (0);
                   9409:   }
                   9410:     
1.234     brouard  9411:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9412:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9413:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9414:   }
                   9415:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9416:     if(nbocc(resultsav,'=') >1){
                   9417:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9418:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9419:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9420:     }else
                   9421:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9422:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9423:     
1.230     brouard  9424:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9425:     Tvarsel[k]=atoi(strc);
                   9426:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9427:     /* cptcovsel++;     */
                   9428:     if (nbocc(stra,'=') >0)
                   9429:       strcpy(resultsav,stra); /* and analyzes it */
                   9430:   }
1.235     brouard  9431:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9432:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9433:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9434:       match=0;
1.236     brouard  9435:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9436:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9437:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9438:          match=1;
                   9439:          break;
                   9440:        }
                   9441:       }
                   9442:       if(match == 0){
                   9443:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9444:       }
                   9445:     }
                   9446:   }
1.235     brouard  9447:   /* Checking for missing or useless values in comparison of current model needs */
                   9448:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9449:     match=0;
1.235     brouard  9450:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9451:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9452:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9453:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9454:          ++match;
                   9455:        }
                   9456:       }
                   9457:     }
                   9458:     if(match == 0){
                   9459:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9460:     }else if(match > 1){
                   9461:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9462:     }
                   9463:   }
1.235     brouard  9464:       
1.234     brouard  9465:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9466:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9467:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9468:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9469:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9470:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9471:   /*    1 0 0 0 */
                   9472:   /*    2 1 0 0 */
                   9473:   /*    3 0 1 0 */ 
                   9474:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9475:   /*    5 0 0 1 */
                   9476:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9477:   /*    7 0 1 1 */
                   9478:   /*    8 1 1 1 */
1.237     brouard  9479:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9480:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9481:   /* V5*age V5 known which value for nres?  */
                   9482:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9483:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9484:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9485:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9486:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9487:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9488:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9489:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9490:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9491:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9492:       k4++;;
                   9493:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9494:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9495:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9496:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9497:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9498:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9499:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9500:       k4q++;;
                   9501:     }
                   9502:   }
1.234     brouard  9503:   
1.235     brouard  9504:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9505:   return (0);
                   9506: }
1.235     brouard  9507: 
1.230     brouard  9508: int decodemodel( char model[], int lastobs)
                   9509:  /**< This routine decodes the model and returns:
1.224     brouard  9510:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9511:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9512:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9513:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9514:        * - cptcovage number of covariates with age*products =2
                   9515:        * - cptcovs number of simple covariates
                   9516:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9517:        *     which is a new column after the 9 (ncovcol) variables. 
                   9518:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9519:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9520:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9521:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9522:        */
1.136     brouard  9523: {
1.238     brouard  9524:   int i, j, k, ks, v;
1.227     brouard  9525:   int  j1, k1, k2, k3, k4;
1.136     brouard  9526:   char modelsav[80];
1.145     brouard  9527:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9528:   char *strpt;
1.136     brouard  9529: 
1.145     brouard  9530:   /*removespace(model);*/
1.136     brouard  9531:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9532:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9533:     if (strstr(model,"AGE") !=0){
1.192     brouard  9534:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9535:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9536:       return 1;
                   9537:     }
1.141     brouard  9538:     if (strstr(model,"v") !=0){
                   9539:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9540:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9541:       return 1;
                   9542:     }
1.187     brouard  9543:     strcpy(modelsav,model); 
                   9544:     if ((strpt=strstr(model,"age*age")) !=0){
                   9545:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9546:       if(strpt != model){
1.234     brouard  9547:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9548:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9549:  corresponding column of parameters.\n",model);
1.234     brouard  9550:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9551:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9552:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9553:        return 1;
1.225     brouard  9554:       }
1.187     brouard  9555:       nagesqr=1;
                   9556:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9557:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9558:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9559:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9560:       else 
1.234     brouard  9561:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9562:     }else
                   9563:       nagesqr=0;
                   9564:     if (strlen(modelsav) >1){
                   9565:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9566:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9567:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9568:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9569:                     * cst, age and age*age 
                   9570:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9571:       /* including age products which are counted in cptcovage.
                   9572:        * but the covariates which are products must be treated 
                   9573:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9574:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9575:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9576:       
                   9577:       
1.187     brouard  9578:       /*   Design
                   9579:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9580:        *  <          ncovcol=8                >
                   9581:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9582:        *   k=  1    2      3       4     5       6      7        8
                   9583:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9584:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9585:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9586:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9587:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9588:        *  Tage[++cptcovage]=k
                   9589:        *       if products, new covar are created after ncovcol with k1
                   9590:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9591:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9592:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9593:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9594:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9595:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9596:        *  <          ncovcol=8                >
                   9597:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9598:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9599:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9600:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9601:        * p Tprod[1]@2={                         6, 5}
                   9602:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9603:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9604:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9605:        *How to reorganize?
                   9606:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9607:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9608:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9609:        * Struct []
                   9610:        */
1.225     brouard  9611:       
1.187     brouard  9612:       /* This loop fills the array Tvar from the string 'model'.*/
                   9613:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9614:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9615:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9616:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9617:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9618:       /*       k=1 Tvar[1]=2 (from V2) */
                   9619:       /*       k=5 Tvar[5] */
                   9620:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9621:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9622:       /*       } */
1.198     brouard  9623:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9624:       /*
                   9625:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9626:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9627:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9628:       }
1.187     brouard  9629:       cptcovage=0;
                   9630:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9631:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9632:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9633:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9634:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9635:        /*scanf("%d",i);*/
                   9636:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9637:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9638:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9639:            /* covar is not filled and then is empty */
                   9640:            cptcovprod--;
                   9641:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9642:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9643:            Typevar[k]=1;  /* 1 for age product */
                   9644:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9645:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9646:            /*printf("stre=%s ", stre);*/
                   9647:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9648:            cptcovprod--;
                   9649:            cutl(stre,strb,strc,'V');
                   9650:            Tvar[k]=atoi(stre);
                   9651:            Typevar[k]=1;  /* 1 for age product */
                   9652:            cptcovage++;
                   9653:            Tage[cptcovage]=k;
                   9654:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9655:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9656:            cptcovn++;
                   9657:            cptcovprodnoage++;k1++;
                   9658:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9659:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9660:                                                because this model-covariate is a construction we invent a new column
                   9661:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9662:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9663:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9664:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9665:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9666:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9667:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9668:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9669:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9670:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9671:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9672:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9673:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9674:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9675:            for (i=1; i<=lastobs;i++){
                   9676:              /* Computes the new covariate which is a product of
                   9677:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9678:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9679:            }
                   9680:          } /* End age is not in the model */
                   9681:        } /* End if model includes a product */
                   9682:        else { /* no more sum */
                   9683:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9684:          /*  scanf("%d",i);*/
                   9685:          cutl(strd,strc,strb,'V');
                   9686:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9687:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9688:          Tvar[k]=atoi(strd);
                   9689:          Typevar[k]=0;  /* 0 for simple covariates */
                   9690:        }
                   9691:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9692:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9693:                                  scanf("%d",i);*/
1.187     brouard  9694:       } /* end of loop + on total covariates */
                   9695:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9696:   } /* end if strlen(model == 0) */
1.136     brouard  9697:   
                   9698:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9699:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9700:   
1.136     brouard  9701:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9702:      printf("cptcovprod=%d ", cptcovprod);
                   9703:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9704:      scanf("%d ",i);*/
                   9705: 
                   9706: 
1.230     brouard  9707: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9708:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9709: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9710:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9711:    k =           1    2   3     4       5       6      7      8        9
                   9712:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9713:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9714:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9715:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9716:          Tmodelind[combination of covar]=k;
1.225     brouard  9717: */  
                   9718: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9719:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9720:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9721:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9722:   printf("Model=%s\n\
                   9723: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9724: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9725: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9726:   fprintf(ficlog,"Model=%s\n\
                   9727: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9728: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9729: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9730:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9731:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9732:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9733:       Fixed[k]= 0;
                   9734:       Dummy[k]= 0;
1.225     brouard  9735:       ncoveff++;
1.232     brouard  9736:       ncovf++;
1.234     brouard  9737:       nsd++;
                   9738:       modell[k].maintype= FTYPE;
                   9739:       TvarsD[nsd]=Tvar[k];
                   9740:       TvarsDind[nsd]=k;
                   9741:       TvarF[ncovf]=Tvar[k];
                   9742:       TvarFind[ncovf]=k;
                   9743:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9744:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9745:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9746:       Fixed[k]= 0;
                   9747:       Dummy[k]= 0;
                   9748:       ncoveff++;
                   9749:       ncovf++;
                   9750:       modell[k].maintype= FTYPE;
                   9751:       TvarF[ncovf]=Tvar[k];
                   9752:       TvarFind[ncovf]=k;
1.230     brouard  9753:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9754:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9755:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9756:       Fixed[k]= 0;
                   9757:       Dummy[k]= 1;
1.230     brouard  9758:       nqfveff++;
1.234     brouard  9759:       modell[k].maintype= FTYPE;
                   9760:       modell[k].subtype= FQ;
                   9761:       nsq++;
                   9762:       TvarsQ[nsq]=Tvar[k];
                   9763:       TvarsQind[nsq]=k;
1.232     brouard  9764:       ncovf++;
1.234     brouard  9765:       TvarF[ncovf]=Tvar[k];
                   9766:       TvarFind[ncovf]=k;
1.231     brouard  9767:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9768:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9769:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9770:       Fixed[k]= 1;
                   9771:       Dummy[k]= 0;
1.225     brouard  9772:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9773:       modell[k].maintype= VTYPE;
                   9774:       modell[k].subtype= VD;
                   9775:       nsd++;
                   9776:       TvarsD[nsd]=Tvar[k];
                   9777:       TvarsDind[nsd]=k;
                   9778:       ncovv++; /* Only simple time varying variables */
                   9779:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9780:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9781:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9782:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9783:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9784:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9785:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9786:       Fixed[k]= 1;
                   9787:       Dummy[k]= 1;
                   9788:       nqtveff++;
                   9789:       modell[k].maintype= VTYPE;
                   9790:       modell[k].subtype= VQ;
                   9791:       ncovv++; /* Only simple time varying variables */
                   9792:       nsq++;
                   9793:       TvarsQ[nsq]=Tvar[k];
                   9794:       TvarsQind[nsq]=k;
                   9795:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9796:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9797:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9798:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9799:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9800:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9801:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9802:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9803:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9804:       ncova++;
                   9805:       TvarA[ncova]=Tvar[k];
                   9806:       TvarAind[ncova]=k;
1.231     brouard  9807:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9808:        Fixed[k]= 2;
                   9809:        Dummy[k]= 2;
                   9810:        modell[k].maintype= ATYPE;
                   9811:        modell[k].subtype= APFD;
                   9812:        /* ncoveff++; */
1.227     brouard  9813:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9814:        Fixed[k]= 2;
                   9815:        Dummy[k]= 3;
                   9816:        modell[k].maintype= ATYPE;
                   9817:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9818:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9819:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9820:        Fixed[k]= 3;
                   9821:        Dummy[k]= 2;
                   9822:        modell[k].maintype= ATYPE;
                   9823:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9824:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9825:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9826:        Fixed[k]= 3;
                   9827:        Dummy[k]= 3;
                   9828:        modell[k].maintype= ATYPE;
                   9829:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9830:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9831:       }
                   9832:     }else if (Typevar[k] == 2) {  /* product without age */
                   9833:       k1=Tposprod[k];
                   9834:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9835:        if(Tvard[k1][2] <=ncovcol){
                   9836:          Fixed[k]= 1;
                   9837:          Dummy[k]= 0;
                   9838:          modell[k].maintype= FTYPE;
                   9839:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9840:          ncovf++; /* Fixed variables without age */
                   9841:          TvarF[ncovf]=Tvar[k];
                   9842:          TvarFind[ncovf]=k;
                   9843:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9844:          Fixed[k]= 0;  /* or 2 ?*/
                   9845:          Dummy[k]= 1;
                   9846:          modell[k].maintype= FTYPE;
                   9847:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9848:          ncovf++; /* Varying variables without age */
                   9849:          TvarF[ncovf]=Tvar[k];
                   9850:          TvarFind[ncovf]=k;
                   9851:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9852:          Fixed[k]= 1;
                   9853:          Dummy[k]= 0;
                   9854:          modell[k].maintype= VTYPE;
                   9855:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9856:          ncovv++; /* Varying variables without age */
                   9857:          TvarV[ncovv]=Tvar[k];
                   9858:          TvarVind[ncovv]=k;
                   9859:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9860:          Fixed[k]= 1;
                   9861:          Dummy[k]= 1;
                   9862:          modell[k].maintype= VTYPE;
                   9863:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9864:          ncovv++; /* Varying variables without age */
                   9865:          TvarV[ncovv]=Tvar[k];
                   9866:          TvarVind[ncovv]=k;
                   9867:        }
1.227     brouard  9868:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9869:        if(Tvard[k1][2] <=ncovcol){
                   9870:          Fixed[k]= 0;  /* or 2 ?*/
                   9871:          Dummy[k]= 1;
                   9872:          modell[k].maintype= FTYPE;
                   9873:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9874:          ncovf++; /* Fixed variables without age */
                   9875:          TvarF[ncovf]=Tvar[k];
                   9876:          TvarFind[ncovf]=k;
                   9877:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9878:          Fixed[k]= 1;
                   9879:          Dummy[k]= 1;
                   9880:          modell[k].maintype= VTYPE;
                   9881:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9882:          ncovv++; /* Varying variables without age */
                   9883:          TvarV[ncovv]=Tvar[k];
                   9884:          TvarVind[ncovv]=k;
                   9885:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9886:          Fixed[k]= 1;
                   9887:          Dummy[k]= 1;
                   9888:          modell[k].maintype= VTYPE;
                   9889:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9890:          ncovv++; /* Varying variables without age */
                   9891:          TvarV[ncovv]=Tvar[k];
                   9892:          TvarVind[ncovv]=k;
                   9893:          ncovv++; /* Varying variables without age */
                   9894:          TvarV[ncovv]=Tvar[k];
                   9895:          TvarVind[ncovv]=k;
                   9896:        }
1.227     brouard  9897:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9898:        if(Tvard[k1][2] <=ncovcol){
                   9899:          Fixed[k]= 1;
                   9900:          Dummy[k]= 1;
                   9901:          modell[k].maintype= VTYPE;
                   9902:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9903:          ncovv++; /* Varying variables without age */
                   9904:          TvarV[ncovv]=Tvar[k];
                   9905:          TvarVind[ncovv]=k;
                   9906:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9907:          Fixed[k]= 1;
                   9908:          Dummy[k]= 1;
                   9909:          modell[k].maintype= VTYPE;
                   9910:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9911:          ncovv++; /* Varying variables without age */
                   9912:          TvarV[ncovv]=Tvar[k];
                   9913:          TvarVind[ncovv]=k;
                   9914:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9915:          Fixed[k]= 1;
                   9916:          Dummy[k]= 0;
                   9917:          modell[k].maintype= VTYPE;
                   9918:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9919:          ncovv++; /* Varying variables without age */
                   9920:          TvarV[ncovv]=Tvar[k];
                   9921:          TvarVind[ncovv]=k;
                   9922:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9923:          Fixed[k]= 1;
                   9924:          Dummy[k]= 1;
                   9925:          modell[k].maintype= VTYPE;
                   9926:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9927:          ncovv++; /* Varying variables without age */
                   9928:          TvarV[ncovv]=Tvar[k];
                   9929:          TvarVind[ncovv]=k;
                   9930:        }
1.227     brouard  9931:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9932:        if(Tvard[k1][2] <=ncovcol){
                   9933:          Fixed[k]= 1;
                   9934:          Dummy[k]= 1;
                   9935:          modell[k].maintype= VTYPE;
                   9936:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9937:          ncovv++; /* Varying variables without age */
                   9938:          TvarV[ncovv]=Tvar[k];
                   9939:          TvarVind[ncovv]=k;
                   9940:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9941:          Fixed[k]= 1;
                   9942:          Dummy[k]= 1;
                   9943:          modell[k].maintype= VTYPE;
                   9944:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9945:          ncovv++; /* Varying variables without age */
                   9946:          TvarV[ncovv]=Tvar[k];
                   9947:          TvarVind[ncovv]=k;
                   9948:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9949:          Fixed[k]= 1;
                   9950:          Dummy[k]= 1;
                   9951:          modell[k].maintype= VTYPE;
                   9952:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9953:          ncovv++; /* Varying variables without age */
                   9954:          TvarV[ncovv]=Tvar[k];
                   9955:          TvarVind[ncovv]=k;
                   9956:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9957:          Fixed[k]= 1;
                   9958:          Dummy[k]= 1;
                   9959:          modell[k].maintype= VTYPE;
                   9960:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9961:          ncovv++; /* Varying variables without age */
                   9962:          TvarV[ncovv]=Tvar[k];
                   9963:          TvarVind[ncovv]=k;
                   9964:        }
1.227     brouard  9965:       }else{
1.240     brouard  9966:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9967:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9968:       } /*end k1*/
1.225     brouard  9969:     }else{
1.226     brouard  9970:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9971:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9972:     }
1.227     brouard  9973:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9974:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9975:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9976:   }
                   9977:   /* Searching for doublons in the model */
                   9978:   for(k1=1; k1<= cptcovt;k1++){
                   9979:     for(k2=1; k2 <k1;k2++){
                   9980:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9981:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9982:          if(Tvar[k1]==Tvar[k2]){
                   9983:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9984:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9985:            return(1);
                   9986:          }
                   9987:        }else if (Typevar[k1] ==2){
                   9988:          k3=Tposprod[k1];
                   9989:          k4=Tposprod[k2];
                   9990:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9991:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9992:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9993:            return(1);
                   9994:          }
                   9995:        }
1.227     brouard  9996:       }
                   9997:     }
1.225     brouard  9998:   }
                   9999:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10000:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10001:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10002:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10003:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10004:   /*endread:*/
1.225     brouard  10005:   printf("Exiting decodemodel: ");
                   10006:   return (1);
1.136     brouard  10007: }
                   10008: 
1.169     brouard  10009: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10010: {/* Check ages at death */
1.136     brouard  10011:   int i, m;
1.218     brouard  10012:   int firstone=0;
                   10013:   
1.136     brouard  10014:   for (i=1; i<=imx; i++) {
                   10015:     for(m=2; (m<= maxwav); m++) {
                   10016:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10017:        anint[m][i]=9999;
1.216     brouard  10018:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10019:          s[m][i]=-1;
1.136     brouard  10020:       }
                   10021:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10022:        *nberr = *nberr + 1;
1.218     brouard  10023:        if(firstone == 0){
                   10024:          firstone=1;
1.260     brouard  10025:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10026:        }
1.262     brouard  10027:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10028:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10029:       }
                   10030:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10031:        (*nberr)++;
1.259     brouard  10032:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10033:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10034:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10035:       }
                   10036:     }
                   10037:   }
                   10038: 
                   10039:   for (i=1; i<=imx; i++)  {
                   10040:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10041:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10042:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10043:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10044:          if(agedc[i]>0){
                   10045:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10046:              agev[m][i]=agedc[i];
1.214     brouard  10047:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10048:            }else {
1.136     brouard  10049:              if ((int)andc[i]!=9999){
                   10050:                nbwarn++;
                   10051:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10052:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10053:                agev[m][i]=-1;
                   10054:              }
                   10055:            }
1.169     brouard  10056:          } /* agedc > 0 */
1.214     brouard  10057:        } /* end if */
1.136     brouard  10058:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10059:                                 years but with the precision of a month */
                   10060:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10061:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10062:            agev[m][i]=1;
                   10063:          else if(agev[m][i] < *agemin){ 
                   10064:            *agemin=agev[m][i];
                   10065:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10066:          }
                   10067:          else if(agev[m][i] >*agemax){
                   10068:            *agemax=agev[m][i];
1.156     brouard  10069:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10070:          }
                   10071:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10072:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10073:        } /* en if 9*/
1.136     brouard  10074:        else { /* =9 */
1.214     brouard  10075:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10076:          agev[m][i]=1;
                   10077:          s[m][i]=-1;
                   10078:        }
                   10079:       }
1.214     brouard  10080:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10081:        agev[m][i]=1;
1.214     brouard  10082:       else{
                   10083:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10084:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10085:        agev[m][i]=0;
                   10086:       }
                   10087:     } /* End for lastpass */
                   10088:   }
1.136     brouard  10089:     
                   10090:   for (i=1; i<=imx; i++)  {
                   10091:     for(m=firstpass; (m<=lastpass); m++){
                   10092:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10093:        (*nberr)++;
1.136     brouard  10094:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10095:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10096:        return 1;
                   10097:       }
                   10098:     }
                   10099:   }
                   10100: 
                   10101:   /*for (i=1; i<=imx; i++){
                   10102:   for (m=firstpass; (m<lastpass); m++){
                   10103:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10104: }
                   10105: 
                   10106: }*/
                   10107: 
                   10108: 
1.139     brouard  10109:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10110:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10111: 
                   10112:   return (0);
1.164     brouard  10113:  /* endread:*/
1.136     brouard  10114:     printf("Exiting calandcheckages: ");
                   10115:     return (1);
                   10116: }
                   10117: 
1.172     brouard  10118: #if defined(_MSC_VER)
                   10119: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10120: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10121: //#include "stdafx.h"
                   10122: //#include <stdio.h>
                   10123: //#include <tchar.h>
                   10124: //#include <windows.h>
                   10125: //#include <iostream>
                   10126: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10127: 
                   10128: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10129: 
                   10130: BOOL IsWow64()
                   10131: {
                   10132:        BOOL bIsWow64 = FALSE;
                   10133: 
                   10134:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10135:        //  (HANDLE, PBOOL);
                   10136: 
                   10137:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10138: 
                   10139:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10140:        const char funcName[] = "IsWow64Process";
                   10141:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10142:                GetProcAddress(module, funcName);
                   10143: 
                   10144:        if (NULL != fnIsWow64Process)
                   10145:        {
                   10146:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10147:                        &bIsWow64))
                   10148:                        //throw std::exception("Unknown error");
                   10149:                        printf("Unknown error\n");
                   10150:        }
                   10151:        return bIsWow64 != FALSE;
                   10152: }
                   10153: #endif
1.177     brouard  10154: 
1.191     brouard  10155: void syscompilerinfo(int logged)
1.167     brouard  10156:  {
                   10157:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10158:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10159:    /* /GS /W3 /Gy
                   10160:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10161:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10162:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10163:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10164:    */ 
                   10165:    /* 64 bits */
1.185     brouard  10166:    /*
                   10167:      /GS /W3 /Gy
                   10168:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10169:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10170:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10171:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10172:    /* Optimization are useless and O3 is slower than O2 */
                   10173:    /*
                   10174:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10175:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10176:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10177:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10178:    */
1.186     brouard  10179:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10180:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10181:       /PDB:"visual studio
                   10182:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10183:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10184:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10185:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10186:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10187:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10188:       uiAccess='false'"
                   10189:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10190:       /NOLOGO /TLBID:1
                   10191:    */
1.177     brouard  10192: #if defined __INTEL_COMPILER
1.178     brouard  10193: #if defined(__GNUC__)
                   10194:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10195: #endif
1.177     brouard  10196: #elif defined(__GNUC__) 
1.179     brouard  10197: #ifndef  __APPLE__
1.174     brouard  10198: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10199: #endif
1.177     brouard  10200:    struct utsname sysInfo;
1.178     brouard  10201:    int cross = CROSS;
                   10202:    if (cross){
                   10203:           printf("Cross-");
1.191     brouard  10204:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10205:    }
1.174     brouard  10206: #endif
                   10207: 
1.171     brouard  10208: #include <stdint.h>
1.178     brouard  10209: 
1.191     brouard  10210:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10211: #if defined(__clang__)
1.191     brouard  10212:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10213: #endif
                   10214: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10215:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10216: #endif
                   10217: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10218:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10219: #endif
                   10220: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10221:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10222: #endif
                   10223: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10224:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10225: #endif
                   10226: #if defined(_MSC_VER)
1.191     brouard  10227:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10228: #endif
                   10229: #if defined(__PGI)
1.191     brouard  10230:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10231: #endif
                   10232: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10233:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10234: #endif
1.191     brouard  10235:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10236:    
1.167     brouard  10237: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10238: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10239:     // Windows (x64 and x86)
1.191     brouard  10240:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10241: #elif __unix__ // all unices, not all compilers
                   10242:     // Unix
1.191     brouard  10243:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10244: #elif __linux__
                   10245:     // linux
1.191     brouard  10246:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10247: #elif __APPLE__
1.174     brouard  10248:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10249:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10250: #endif
                   10251: 
                   10252: /*  __MINGW32__          */
                   10253: /*  __CYGWIN__  */
                   10254: /* __MINGW64__  */
                   10255: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10256: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10257: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10258: /* _WIN64  // Defined for applications for Win64. */
                   10259: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10260: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10261: 
1.167     brouard  10262: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10263:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10264: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10265:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10266: #else
1.191     brouard  10267:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10268: #endif
                   10269: 
1.169     brouard  10270: #if defined(__GNUC__)
                   10271: # if defined(__GNUC_PATCHLEVEL__)
                   10272: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10273:                             + __GNUC_MINOR__ * 100 \
                   10274:                             + __GNUC_PATCHLEVEL__)
                   10275: # else
                   10276: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10277:                             + __GNUC_MINOR__ * 100)
                   10278: # endif
1.174     brouard  10279:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10280:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10281: 
                   10282:    if (uname(&sysInfo) != -1) {
                   10283:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10284:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10285:    }
                   10286:    else
                   10287:       perror("uname() error");
1.179     brouard  10288:    //#ifndef __INTEL_COMPILER 
                   10289: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10290:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10291:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10292: #endif
1.169     brouard  10293: #endif
1.172     brouard  10294: 
                   10295:    //   void main()
                   10296:    //   {
1.169     brouard  10297: #if defined(_MSC_VER)
1.174     brouard  10298:    if (IsWow64()){
1.191     brouard  10299:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10300:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10301:    }
                   10302:    else{
1.191     brouard  10303:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10304:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10305:    }
1.172     brouard  10306:    //     printf("\nPress Enter to continue...");
                   10307:    //     getchar();
                   10308:    //   }
                   10309: 
1.169     brouard  10310: #endif
                   10311:    
1.167     brouard  10312: 
1.219     brouard  10313: }
1.136     brouard  10314: 
1.219     brouard  10315: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10316:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10317:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10318:   /* double ftolpl = 1.e-10; */
1.180     brouard  10319:   double age, agebase, agelim;
1.203     brouard  10320:   double tot;
1.180     brouard  10321: 
1.202     brouard  10322:   strcpy(filerespl,"PL_");
                   10323:   strcat(filerespl,fileresu);
                   10324:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10325:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10326:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10327:   }
1.227     brouard  10328:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10329:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10330:   pstamp(ficrespl);
1.203     brouard  10331:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10332:   fprintf(ficrespl,"#Age ");
                   10333:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10334:   fprintf(ficrespl,"\n");
1.180     brouard  10335:   
1.219     brouard  10336:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10337: 
1.219     brouard  10338:   agebase=ageminpar;
                   10339:   agelim=agemaxpar;
1.180     brouard  10340: 
1.227     brouard  10341:   /* i1=pow(2,ncoveff); */
1.234     brouard  10342:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10343:   if (cptcovn < 1){i1=1;}
1.180     brouard  10344: 
1.238     brouard  10345:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10346:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10347:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10348:        continue;
1.235     brouard  10349: 
1.238     brouard  10350:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10351:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10352:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10353:       /* k=k+1; */
                   10354:       /* to clean */
                   10355:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10356:       fprintf(ficrespl,"#******");
                   10357:       printf("#******");
                   10358:       fprintf(ficlog,"#******");
                   10359:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10360:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10361:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10362:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10363:       }
                   10364:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10365:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10366:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10367:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10368:       }
                   10369:       fprintf(ficrespl,"******\n");
                   10370:       printf("******\n");
                   10371:       fprintf(ficlog,"******\n");
                   10372:       if(invalidvarcomb[k]){
                   10373:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10374:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10375:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10376:        continue;
                   10377:       }
1.219     brouard  10378: 
1.238     brouard  10379:       fprintf(ficrespl,"#Age ");
                   10380:       for(j=1;j<=cptcoveff;j++) {
                   10381:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10382:       }
                   10383:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10384:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10385:     
1.238     brouard  10386:       for (age=agebase; age<=agelim; age++){
                   10387:        /* for (age=agebase; age<=agebase; age++){ */
                   10388:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10389:        fprintf(ficrespl,"%.0f ",age );
                   10390:        for(j=1;j<=cptcoveff;j++)
                   10391:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10392:        tot=0.;
                   10393:        for(i=1; i<=nlstate;i++){
                   10394:          tot +=  prlim[i][i];
                   10395:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10396:        }
                   10397:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10398:       } /* Age */
                   10399:       /* was end of cptcod */
                   10400:     } /* cptcov */
                   10401:   } /* nres */
1.219     brouard  10402:   return 0;
1.180     brouard  10403: }
                   10404: 
1.218     brouard  10405: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10406:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10407:        
                   10408:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10409:    * at any age between ageminpar and agemaxpar
                   10410:         */
1.235     brouard  10411:   int i, j, k, i1, nres=0 ;
1.217     brouard  10412:   /* double ftolpl = 1.e-10; */
                   10413:   double age, agebase, agelim;
                   10414:   double tot;
1.218     brouard  10415:   /* double ***mobaverage; */
                   10416:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10417: 
                   10418:   strcpy(fileresplb,"PLB_");
                   10419:   strcat(fileresplb,fileresu);
                   10420:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10421:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10422:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10423:   }
                   10424:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10425:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10426:   pstamp(ficresplb);
                   10427:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10428:   fprintf(ficresplb,"#Age ");
                   10429:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10430:   fprintf(ficresplb,"\n");
                   10431:   
1.218     brouard  10432:   
                   10433:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10434:   
                   10435:   agebase=ageminpar;
                   10436:   agelim=agemaxpar;
                   10437:   
                   10438:   
1.227     brouard  10439:   i1=pow(2,cptcoveff);
1.218     brouard  10440:   if (cptcovn < 1){i1=1;}
1.227     brouard  10441:   
1.238     brouard  10442:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10443:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10444:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10445:        continue;
                   10446:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10447:       fprintf(ficresplb,"#******");
                   10448:       printf("#******");
                   10449:       fprintf(ficlog,"#******");
                   10450:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10451:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10452:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10453:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10454:       }
                   10455:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10456:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10457:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10458:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10459:       }
                   10460:       fprintf(ficresplb,"******\n");
                   10461:       printf("******\n");
                   10462:       fprintf(ficlog,"******\n");
                   10463:       if(invalidvarcomb[k]){
                   10464:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10465:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10466:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10467:        continue;
                   10468:       }
1.218     brouard  10469:     
1.238     brouard  10470:       fprintf(ficresplb,"#Age ");
                   10471:       for(j=1;j<=cptcoveff;j++) {
                   10472:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10473:       }
                   10474:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10475:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10476:     
                   10477:     
1.238     brouard  10478:       for (age=agebase; age<=agelim; age++){
                   10479:        /* for (age=agebase; age<=agebase; age++){ */
                   10480:        if(mobilavproj > 0){
                   10481:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10482:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10483:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10484:        }else if (mobilavproj == 0){
                   10485:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10486:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10487:          exit(1);
                   10488:        }else{
                   10489:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10490:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10491:          /* printf("TOTOT\n"); */
                   10492:           /* exit(1); */
1.238     brouard  10493:        }
                   10494:        fprintf(ficresplb,"%.0f ",age );
                   10495:        for(j=1;j<=cptcoveff;j++)
                   10496:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10497:        tot=0.;
                   10498:        for(i=1; i<=nlstate;i++){
                   10499:          tot +=  bprlim[i][i];
                   10500:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10501:        }
                   10502:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10503:       } /* Age */
                   10504:       /* was end of cptcod */
1.255     brouard  10505:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10506:     } /* end of any combination */
                   10507:   } /* end of nres */  
1.218     brouard  10508:   /* hBijx(p, bage, fage); */
                   10509:   /* fclose(ficrespijb); */
                   10510:   
                   10511:   return 0;
1.217     brouard  10512: }
1.218     brouard  10513:  
1.180     brouard  10514: int hPijx(double *p, int bage, int fage){
                   10515:     /*------------- h Pij x at various ages ------------*/
                   10516: 
                   10517:   int stepsize;
                   10518:   int agelim;
                   10519:   int hstepm;
                   10520:   int nhstepm;
1.235     brouard  10521:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10522: 
                   10523:   double agedeb;
                   10524:   double ***p3mat;
                   10525: 
1.201     brouard  10526:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10527:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10528:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10529:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10530:     }
                   10531:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10532:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10533:   
                   10534:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10535:     /*if (stepm<=24) stepsize=2;*/
                   10536: 
                   10537:     agelim=AGESUP;
                   10538:     hstepm=stepsize*YEARM; /* Every year of age */
                   10539:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10540:                
1.180     brouard  10541:     /* hstepm=1;   aff par mois*/
                   10542:     pstamp(ficrespij);
                   10543:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10544:     i1= pow(2,cptcoveff);
1.218     brouard  10545:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10546:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10547:                /*      k=k+1;  */
1.235     brouard  10548:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10549:     for(k=1; k<=i1;k++){
1.253     brouard  10550:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10551:        continue;
1.183     brouard  10552:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10553:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10554:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10555:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10556:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10557:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10558:       }
1.183     brouard  10559:       fprintf(ficrespij,"******\n");
                   10560:       
                   10561:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10562:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10563:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10564:        
                   10565:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10566:        
1.183     brouard  10567:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10568:        oldm=oldms;savm=savms;
1.235     brouard  10569:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10570:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10571:        for(i=1; i<=nlstate;i++)
                   10572:          for(j=1; j<=nlstate+ndeath;j++)
                   10573:            fprintf(ficrespij," %1d-%1d",i,j);
                   10574:        fprintf(ficrespij,"\n");
                   10575:        for (h=0; h<=nhstepm; h++){
                   10576:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10577:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10578:          for(i=1; i<=nlstate;i++)
                   10579:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10580:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10581:          fprintf(ficrespij,"\n");
                   10582:        }
1.183     brouard  10583:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10584:        fprintf(ficrespij,"\n");
                   10585:       }
1.180     brouard  10586:       /*}*/
                   10587:     }
1.218     brouard  10588:     return 0;
1.180     brouard  10589: }
1.218     brouard  10590:  
                   10591:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10592:     /*------------- h Bij x at various ages ------------*/
                   10593: 
                   10594:   int stepsize;
1.218     brouard  10595:   /* int agelim; */
                   10596:        int ageminl;
1.217     brouard  10597:   int hstepm;
                   10598:   int nhstepm;
1.238     brouard  10599:   int h, i, i1, j, k, nres;
1.218     brouard  10600:        
1.217     brouard  10601:   double agedeb;
                   10602:   double ***p3mat;
1.218     brouard  10603:        
                   10604:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10605:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10606:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10607:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10608:   }
                   10609:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10610:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10611:   
                   10612:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10613:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10614:   
1.218     brouard  10615:   /* agelim=AGESUP; */
                   10616:   ageminl=30;
                   10617:   hstepm=stepsize*YEARM; /* Every year of age */
                   10618:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10619:   
                   10620:   /* hstepm=1;   aff par mois*/
                   10621:   pstamp(ficrespijb);
1.255     brouard  10622:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10623:   i1= pow(2,cptcoveff);
1.218     brouard  10624:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10625:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10626:   /*   k=k+1;  */
1.238     brouard  10627:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10628:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10629:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10630:        continue;
                   10631:       fprintf(ficrespijb,"\n#****** ");
                   10632:       for(j=1;j<=cptcoveff;j++)
                   10633:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10634:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10635:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10636:       }
                   10637:       fprintf(ficrespijb,"******\n");
1.264     brouard  10638:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10639:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10640:        continue;
                   10641:       }
                   10642:       
                   10643:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10644:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10645:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10646:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10647:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10648:        
                   10649:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10650:        
1.266     brouard  10651:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10652:        /* and memory limitations if stepm is small */
                   10653: 
1.238     brouard  10654:        /* oldm=oldms;savm=savms; */
                   10655:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10656:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10657:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10658:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10659:        for(i=1; i<=nlstate;i++)
                   10660:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10661:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10662:        fprintf(ficrespijb,"\n");
1.238     brouard  10663:        for (h=0; h<=nhstepm; h++){
                   10664:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10665:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10666:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10667:          for(i=1; i<=nlstate;i++)
                   10668:            for(j=1; j<=nlstate+ndeath;j++)
                   10669:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10670:          fprintf(ficrespijb,"\n");
                   10671:        }
                   10672:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10673:        fprintf(ficrespijb,"\n");
                   10674:       } /* end age deb */
                   10675:     } /* end combination */
                   10676:   } /* end nres */
1.218     brouard  10677:   return 0;
                   10678:  } /*  hBijx */
1.217     brouard  10679: 
1.180     brouard  10680: 
1.136     brouard  10681: /***********************************************/
                   10682: /**************** Main Program *****************/
                   10683: /***********************************************/
                   10684: 
                   10685: int main(int argc, char *argv[])
                   10686: {
                   10687: #ifdef GSL
                   10688:   const gsl_multimin_fminimizer_type *T;
                   10689:   size_t iteri = 0, it;
                   10690:   int rval = GSL_CONTINUE;
                   10691:   int status = GSL_SUCCESS;
                   10692:   double ssval;
                   10693: #endif
                   10694:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10695:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10696:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10697:   int jj, ll, li, lj, lk;
1.136     brouard  10698:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10699:   int num_filled;
1.136     brouard  10700:   int itimes;
                   10701:   int NDIM=2;
                   10702:   int vpopbased=0;
1.235     brouard  10703:   int nres=0;
1.258     brouard  10704:   int endishere=0;
1.277     brouard  10705:   int noffset=0;
1.274     brouard  10706:   int ncurrv=0; /* Temporary variable */
                   10707:   
1.164     brouard  10708:   char ca[32], cb[32];
1.136     brouard  10709:   /*  FILE *fichtm; *//* Html File */
                   10710:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10711:   struct stat info;
1.191     brouard  10712:   double agedeb=0.;
1.194     brouard  10713: 
                   10714:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10715:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10716: 
1.165     brouard  10717:   double fret;
1.191     brouard  10718:   double dum=0.; /* Dummy variable */
1.136     brouard  10719:   double ***p3mat;
1.218     brouard  10720:   /* double ***mobaverage; */
1.164     brouard  10721: 
                   10722:   char line[MAXLINE];
1.197     brouard  10723:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10724: 
1.234     brouard  10725:   char  modeltemp[MAXLINE];
1.230     brouard  10726:   char resultline[MAXLINE];
                   10727:   
1.136     brouard  10728:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10729:   char *tok, *val; /* pathtot */
1.136     brouard  10730:   int firstobs=1, lastobs=10;
1.195     brouard  10731:   int c,  h , cpt, c2;
1.191     brouard  10732:   int jl=0;
                   10733:   int i1, j1, jk, stepsize=0;
1.194     brouard  10734:   int count=0;
                   10735: 
1.164     brouard  10736:   int *tab; 
1.136     brouard  10737:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10738:   int backcast=0;
1.136     brouard  10739:   int mobilav=0,popforecast=0;
1.191     brouard  10740:   int hstepm=0, nhstepm=0;
1.136     brouard  10741:   int agemortsup;
                   10742:   float  sumlpop=0.;
                   10743:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10744:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10745: 
1.191     brouard  10746:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10747:   double ftolpl=FTOL;
                   10748:   double **prlim;
1.217     brouard  10749:   double **bprlim;
1.136     brouard  10750:   double ***param; /* Matrix of parameters */
1.251     brouard  10751:   double ***paramstart; /* Matrix of starting parameter values */
                   10752:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10753:   double **matcov; /* Matrix of covariance */
1.203     brouard  10754:   double **hess; /* Hessian matrix */
1.136     brouard  10755:   double ***delti3; /* Scale */
                   10756:   double *delti; /* Scale */
                   10757:   double ***eij, ***vareij;
                   10758:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10759: 
1.136     brouard  10760:   double *epj, vepp;
1.164     brouard  10761: 
1.273     brouard  10762:   double dateprev1, dateprev2;
                   10763:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10764:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10765: 
1.136     brouard  10766:   double **ximort;
1.145     brouard  10767:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10768:   int *dcwave;
                   10769: 
1.164     brouard  10770:   char z[1]="c";
1.136     brouard  10771: 
                   10772:   /*char  *strt;*/
                   10773:   char strtend[80];
1.126     brouard  10774: 
1.164     brouard  10775: 
1.126     brouard  10776: /*   setlocale (LC_ALL, ""); */
                   10777: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10778: /*   textdomain (PACKAGE); */
                   10779: /*   setlocale (LC_CTYPE, ""); */
                   10780: /*   setlocale (LC_MESSAGES, ""); */
                   10781: 
                   10782:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10783:   rstart_time = time(NULL);  
                   10784:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10785:   start_time = *localtime(&rstart_time);
1.126     brouard  10786:   curr_time=start_time;
1.157     brouard  10787:   /*tml = *localtime(&start_time.tm_sec);*/
                   10788:   /* strcpy(strstart,asctime(&tml)); */
                   10789:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10790: 
                   10791: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10792: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10793: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10794: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10795: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10796: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10797: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10798: /*   strt=asctime(&tmg); */
                   10799: /*   printf("Time(after) =%s",strstart);  */
                   10800: /*  (void) time (&time_value);
                   10801: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10802: *  tm = *localtime(&time_value);
                   10803: *  strstart=asctime(&tm);
                   10804: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10805: */
                   10806: 
                   10807:   nberr=0; /* Number of errors and warnings */
                   10808:   nbwarn=0;
1.184     brouard  10809: #ifdef WIN32
                   10810:   _getcwd(pathcd, size);
                   10811: #else
1.126     brouard  10812:   getcwd(pathcd, size);
1.184     brouard  10813: #endif
1.191     brouard  10814:   syscompilerinfo(0);
1.196     brouard  10815:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10816:   if(argc <=1){
                   10817:     printf("\nEnter the parameter file name: ");
1.205     brouard  10818:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10819:       printf("ERROR Empty parameter file name\n");
                   10820:       goto end;
                   10821:     }
1.126     brouard  10822:     i=strlen(pathr);
                   10823:     if(pathr[i-1]=='\n')
                   10824:       pathr[i-1]='\0';
1.156     brouard  10825:     i=strlen(pathr);
1.205     brouard  10826:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10827:       pathr[i-1]='\0';
1.205     brouard  10828:     }
                   10829:     i=strlen(pathr);
                   10830:     if( i==0 ){
                   10831:       printf("ERROR Empty parameter file name\n");
                   10832:       goto end;
                   10833:     }
                   10834:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10835:       printf("Pathr |%s|\n",pathr);
                   10836:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10837:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10838:       strcpy (pathtot, val);
                   10839:       if(pathr[0] == '\0') break; /* Dirty */
                   10840:     }
                   10841:   }
1.281     brouard  10842:   else if (argc<=2){
                   10843:     strcpy(pathtot,argv[1]);
                   10844:   }
1.126     brouard  10845:   else{
                   10846:     strcpy(pathtot,argv[1]);
1.281     brouard  10847:     strcpy(z,argv[2]);
                   10848:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10849:   }
                   10850:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10851:   /*cygwin_split_path(pathtot,path,optionfile);
                   10852:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10853:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10854: 
                   10855:   /* Split argv[0], imach program to get pathimach */
                   10856:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10857:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10858:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10859:  /*   strcpy(pathimach,argv[0]); */
                   10860:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10861:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10862:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10863: #ifdef WIN32
                   10864:   _chdir(path); /* Can be a relative path */
                   10865:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10866: #else
1.126     brouard  10867:   chdir(path); /* Can be a relative path */
1.184     brouard  10868:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10869: #endif
                   10870:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10871:   strcpy(command,"mkdir ");
                   10872:   strcat(command,optionfilefiname);
                   10873:   if((outcmd=system(command)) != 0){
1.169     brouard  10874:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10875:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10876:     /* fclose(ficlog); */
                   10877: /*     exit(1); */
                   10878:   }
                   10879: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10880: /*     perror("mkdir"); */
                   10881: /*   } */
                   10882: 
                   10883:   /*-------- arguments in the command line --------*/
                   10884: 
1.186     brouard  10885:   /* Main Log file */
1.126     brouard  10886:   strcat(filelog, optionfilefiname);
                   10887:   strcat(filelog,".log");    /* */
                   10888:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10889:     printf("Problem with logfile %s\n",filelog);
                   10890:     goto end;
                   10891:   }
                   10892:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10893:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10894:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10895:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10896:  path=%s \n\
                   10897:  optionfile=%s\n\
                   10898:  optionfilext=%s\n\
1.156     brouard  10899:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10900: 
1.197     brouard  10901:   syscompilerinfo(1);
1.167     brouard  10902: 
1.126     brouard  10903:   printf("Local time (at start):%s",strstart);
                   10904:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10905:   fflush(ficlog);
                   10906: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10907: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10908: 
                   10909:   /* */
                   10910:   strcpy(fileres,"r");
                   10911:   strcat(fileres, optionfilefiname);
1.201     brouard  10912:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10913:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10914:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10915: 
1.186     brouard  10916:   /* Main ---------arguments file --------*/
1.126     brouard  10917: 
                   10918:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10919:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10920:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10921:     fflush(ficlog);
1.149     brouard  10922:     /* goto end; */
                   10923:     exit(70); 
1.126     brouard  10924:   }
                   10925: 
                   10926:   strcpy(filereso,"o");
1.201     brouard  10927:   strcat(filereso,fileresu);
1.126     brouard  10928:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10929:     printf("Problem with Output resultfile: %s\n", filereso);
                   10930:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10931:     fflush(ficlog);
                   10932:     goto end;
                   10933:   }
1.278     brouard  10934:       /*-------- Rewriting parameter file ----------*/
                   10935:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10936:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10937:   strcat(rfileres,".");    /* */
                   10938:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10939:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10940:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10941:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10942:     fflush(ficlog);
                   10943:     goto end;
                   10944:   }
                   10945:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10946: 
1.278     brouard  10947:                                      
1.126     brouard  10948:   /* Reads comments: lines beginning with '#' */
                   10949:   numlinepar=0;
1.277     brouard  10950:   /* Is it a BOM UTF-8 Windows file? */
                   10951:   /* First parameter line */
1.197     brouard  10952:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10953:     noffset=0;
                   10954:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10955:     {
                   10956:       noffset=noffset+3;
                   10957:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10958:     }
                   10959:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10960:     {
                   10961:       noffset=noffset+2;
                   10962:       printf("# File is an UTF16BE BOM file\n");
                   10963:     }
                   10964:     else if( line[0] == 0 && line[1] == 0)
                   10965:     {
                   10966:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   10967:        noffset=noffset+4;
                   10968:        printf("# File is an UTF16BE BOM file\n");
                   10969:       }
                   10970:     } else{
                   10971:       ;/*printf(" Not a BOM file\n");*/
                   10972:     }
                   10973:   
1.197     brouard  10974:     /* If line starts with a # it is a comment */
1.277     brouard  10975:     if (line[noffset] == '#') {
1.197     brouard  10976:       numlinepar++;
                   10977:       fputs(line,stdout);
                   10978:       fputs(line,ficparo);
1.278     brouard  10979:       fputs(line,ficres);
1.197     brouard  10980:       fputs(line,ficlog);
                   10981:       continue;
                   10982:     }else
                   10983:       break;
                   10984:   }
                   10985:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10986:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10987:     if (num_filled != 5) {
                   10988:       printf("Should be 5 parameters\n");
1.283     brouard  10989:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  10990:     }
1.126     brouard  10991:     numlinepar++;
1.197     brouard  10992:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  10993:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10994:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10995:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  10996:   }
                   10997:   /* Second parameter line */
                   10998:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  10999:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11000:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11001:     if (line[0] == '#') {
                   11002:       numlinepar++;
1.283     brouard  11003:       printf("%s",line);
                   11004:       fprintf(ficres,"%s",line);
                   11005:       fprintf(ficparo,"%s",line);
                   11006:       fprintf(ficlog,"%s",line);
1.197     brouard  11007:       continue;
                   11008:     }else
                   11009:       break;
                   11010:   }
1.223     brouard  11011:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11012:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11013:     if (num_filled != 11) {
                   11014:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11015:       printf("but line=%s\n",line);
1.283     brouard  11016:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11017:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11018:     }
1.223     brouard  11019:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11020:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
                   11021:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
                   11022:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11023:   }
1.203     brouard  11024:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11025:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11026:   /* Third parameter line */
                   11027:   while(fgets(line, MAXLINE, ficpar)) {
                   11028:     /* If line starts with a # it is a comment */
                   11029:     if (line[0] == '#') {
                   11030:       numlinepar++;
1.283     brouard  11031:       printf("%s",line);
                   11032:       fprintf(ficres,"%s",line);
                   11033:       fprintf(ficparo,"%s",line);
                   11034:       fprintf(ficlog,"%s",line);
1.197     brouard  11035:       continue;
                   11036:     }else
                   11037:       break;
                   11038:   }
1.201     brouard  11039:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11040:     if (num_filled != 1){
                   11041:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11042:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11043:       model[0]='\0';
                   11044:       goto end;
                   11045:     }
                   11046:     else{
                   11047:       if (model[0]=='+'){
                   11048:        for(i=1; i<=strlen(model);i++)
                   11049:          modeltemp[i-1]=model[i];
1.201     brouard  11050:        strcpy(model,modeltemp); 
1.197     brouard  11051:       }
                   11052:     }
1.199     brouard  11053:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11054:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11055:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11056:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11057:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11058:   }
                   11059:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11060:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11061:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11062:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11063:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11064:   fflush(ficlog);
1.190     brouard  11065:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11066:   if(model[0]=='#'){
1.279     brouard  11067:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11068:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11069:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11070:     if(mle != -1){
1.279     brouard  11071:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11072:       exit(1);
                   11073:     }
                   11074:   }
1.126     brouard  11075:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11076:     ungetc(c,ficpar);
                   11077:     fgets(line, MAXLINE, ficpar);
                   11078:     numlinepar++;
1.195     brouard  11079:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11080:       z[0]=line[1];
                   11081:     }
                   11082:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11083:     fputs(line, stdout);
                   11084:     //puts(line);
1.126     brouard  11085:     fputs(line,ficparo);
                   11086:     fputs(line,ficlog);
                   11087:   }
                   11088:   ungetc(c,ficpar);
                   11089: 
                   11090:    
1.145     brouard  11091:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11092:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11093:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11094:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11095:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11096:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11097:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11098:   */
                   11099:   if (strlen(model)>1) 
1.187     brouard  11100:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11101:   else
1.187     brouard  11102:     ncovmodel=2; /* Constant and age */
1.133     brouard  11103:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11104:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11105:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11106:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11107:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11108:     fflush(stdout);
                   11109:     fclose (ficlog);
                   11110:     goto end;
                   11111:   }
1.126     brouard  11112:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11113:   delti=delti3[1][1];
                   11114:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11115:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11116: /* We could also provide initial parameters values giving by simple logistic regression 
                   11117:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11118:       /* for(i=1;i<nlstate;i++){ */
                   11119:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11120:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11121:       /* } */
1.126     brouard  11122:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11123:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11124:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11125:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11126:     fclose (ficparo);
                   11127:     fclose (ficlog);
                   11128:     goto end;
                   11129:     exit(0);
1.220     brouard  11130:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11131:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11132:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11133:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11134:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11135:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11136:     hess=matrix(1,npar,1,npar);
1.220     brouard  11137:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11138:     /* Read guessed parameters */
1.126     brouard  11139:     /* Reads comments: lines beginning with '#' */
                   11140:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11141:       ungetc(c,ficpar);
                   11142:       fgets(line, MAXLINE, ficpar);
                   11143:       numlinepar++;
1.141     brouard  11144:       fputs(line,stdout);
1.126     brouard  11145:       fputs(line,ficparo);
                   11146:       fputs(line,ficlog);
                   11147:     }
                   11148:     ungetc(c,ficpar);
                   11149:     
                   11150:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11151:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11152:     for(i=1; i <=nlstate; i++){
1.234     brouard  11153:       j=0;
1.126     brouard  11154:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11155:        if(jj==i) continue;
                   11156:        j++;
                   11157:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11158:        if ((i1 != i) || (j1 != jj)){
                   11159:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11160: It might be a problem of design; if ncovcol and the model are correct\n \
                   11161: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11162:          exit(1);
                   11163:        }
                   11164:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11165:        if(mle==1)
                   11166:          printf("%1d%1d",i,jj);
                   11167:        fprintf(ficlog,"%1d%1d",i,jj);
                   11168:        for(k=1; k<=ncovmodel;k++){
                   11169:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11170:          if(mle==1){
                   11171:            printf(" %lf",param[i][j][k]);
                   11172:            fprintf(ficlog," %lf",param[i][j][k]);
                   11173:          }
                   11174:          else
                   11175:            fprintf(ficlog," %lf",param[i][j][k]);
                   11176:          fprintf(ficparo," %lf",param[i][j][k]);
                   11177:        }
                   11178:        fscanf(ficpar,"\n");
                   11179:        numlinepar++;
                   11180:        if(mle==1)
                   11181:          printf("\n");
                   11182:        fprintf(ficlog,"\n");
                   11183:        fprintf(ficparo,"\n");
1.126     brouard  11184:       }
                   11185:     }  
                   11186:     fflush(ficlog);
1.234     brouard  11187:     
1.251     brouard  11188:     /* Reads parameters values */
1.126     brouard  11189:     p=param[1][1];
1.251     brouard  11190:     pstart=paramstart[1][1];
1.126     brouard  11191:     
                   11192:     /* Reads comments: lines beginning with '#' */
                   11193:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11194:       ungetc(c,ficpar);
                   11195:       fgets(line, MAXLINE, ficpar);
                   11196:       numlinepar++;
1.141     brouard  11197:       fputs(line,stdout);
1.126     brouard  11198:       fputs(line,ficparo);
                   11199:       fputs(line,ficlog);
                   11200:     }
                   11201:     ungetc(c,ficpar);
                   11202: 
                   11203:     for(i=1; i <=nlstate; i++){
                   11204:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11205:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11206:        if ( (i1-i) * (j1-j) != 0){
                   11207:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11208:          exit(1);
                   11209:        }
                   11210:        printf("%1d%1d",i,j);
                   11211:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11212:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11213:        for(k=1; k<=ncovmodel;k++){
                   11214:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11215:          printf(" %le",delti3[i][j][k]);
                   11216:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11217:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11218:        }
                   11219:        fscanf(ficpar,"\n");
                   11220:        numlinepar++;
                   11221:        printf("\n");
                   11222:        fprintf(ficparo,"\n");
                   11223:        fprintf(ficlog,"\n");
1.126     brouard  11224:       }
                   11225:     }
                   11226:     fflush(ficlog);
1.234     brouard  11227:     
1.145     brouard  11228:     /* Reads covariance matrix */
1.126     brouard  11229:     delti=delti3[1][1];
1.220     brouard  11230:                
                   11231:                
1.126     brouard  11232:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11233:                
1.126     brouard  11234:     /* Reads comments: lines beginning with '#' */
                   11235:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11236:       ungetc(c,ficpar);
                   11237:       fgets(line, MAXLINE, ficpar);
                   11238:       numlinepar++;
1.141     brouard  11239:       fputs(line,stdout);
1.126     brouard  11240:       fputs(line,ficparo);
                   11241:       fputs(line,ficlog);
                   11242:     }
                   11243:     ungetc(c,ficpar);
1.220     brouard  11244:                
1.126     brouard  11245:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11246:     hess=matrix(1,npar,1,npar);
1.131     brouard  11247:     for(i=1; i <=npar; i++)
                   11248:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11249:                
1.194     brouard  11250:     /* Scans npar lines */
1.126     brouard  11251:     for(i=1; i <=npar; i++){
1.226     brouard  11252:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11253:       if(count != 3){
1.226     brouard  11254:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11255: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11256: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11257:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11258: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11259: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11260:        exit(1);
1.220     brouard  11261:       }else{
1.226     brouard  11262:        if(mle==1)
                   11263:          printf("%1d%1d%d",i1,j1,jk);
                   11264:       }
                   11265:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11266:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11267:       for(j=1; j <=i; j++){
1.226     brouard  11268:        fscanf(ficpar," %le",&matcov[i][j]);
                   11269:        if(mle==1){
                   11270:          printf(" %.5le",matcov[i][j]);
                   11271:        }
                   11272:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11273:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11274:       }
                   11275:       fscanf(ficpar,"\n");
                   11276:       numlinepar++;
                   11277:       if(mle==1)
1.220     brouard  11278:                                printf("\n");
1.126     brouard  11279:       fprintf(ficlog,"\n");
                   11280:       fprintf(ficparo,"\n");
                   11281:     }
1.194     brouard  11282:     /* End of read covariance matrix npar lines */
1.126     brouard  11283:     for(i=1; i <=npar; i++)
                   11284:       for(j=i+1;j<=npar;j++)
1.226     brouard  11285:        matcov[i][j]=matcov[j][i];
1.126     brouard  11286:     
                   11287:     if(mle==1)
                   11288:       printf("\n");
                   11289:     fprintf(ficlog,"\n");
                   11290:     
                   11291:     fflush(ficlog);
                   11292:     
                   11293:   }    /* End of mle != -3 */
1.218     brouard  11294:   
1.186     brouard  11295:   /*  Main data
                   11296:    */
1.126     brouard  11297:   n= lastobs;
                   11298:   num=lvector(1,n);
                   11299:   moisnais=vector(1,n);
                   11300:   annais=vector(1,n);
                   11301:   moisdc=vector(1,n);
                   11302:   andc=vector(1,n);
1.220     brouard  11303:   weight=vector(1,n);
1.126     brouard  11304:   agedc=vector(1,n);
                   11305:   cod=ivector(1,n);
1.220     brouard  11306:   for(i=1;i<=n;i++){
1.234     brouard  11307:     num[i]=0;
                   11308:     moisnais[i]=0;
                   11309:     annais[i]=0;
                   11310:     moisdc[i]=0;
                   11311:     andc[i]=0;
                   11312:     agedc[i]=0;
                   11313:     cod[i]=0;
                   11314:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11315:   }
1.126     brouard  11316:   mint=matrix(1,maxwav,1,n);
                   11317:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11318:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11319:   tab=ivector(1,NCOVMAX);
1.144     brouard  11320:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11321:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11322: 
1.136     brouard  11323:   /* Reads data from file datafile */
                   11324:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11325:     goto end;
                   11326: 
                   11327:   /* Calculation of the number of parameters from char model */
1.234     brouard  11328:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11329:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11330:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11331:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11332:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11333:   */
                   11334:   
                   11335:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11336:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11337:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11338:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11339:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11340:   TvarF=ivector(1,NCOVMAX); /*  */
                   11341:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11342:   TvarV=ivector(1,NCOVMAX); /*  */
                   11343:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11344:   TvarA=ivector(1,NCOVMAX); /*  */
                   11345:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11346:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11347:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11348:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11349:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11350:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11351:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11352:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11353:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11354: 
1.230     brouard  11355:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11356:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11357:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11358:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11359:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11360:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11361:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11362:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11363:   */
                   11364:   /* For model-covariate k tells which data-covariate to use but
                   11365:     because this model-covariate is a construction we invent a new column
                   11366:     ncovcol + k1
                   11367:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11368:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11369:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11370:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11371:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11372:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11373:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11374:   */
1.145     brouard  11375:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11376:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11377:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11378:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11379:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11380:                         4 covariates (3 plus signs)
                   11381:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11382:                      */  
1.230     brouard  11383:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11384:                                * individual dummy, fixed or varying:
                   11385:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11386:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11387:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11388:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11389:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11390:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11391:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11392:                                * individual quantitative, fixed or varying:
                   11393:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11394:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11395:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11396: /* Main decodemodel */
                   11397: 
1.187     brouard  11398: 
1.223     brouard  11399:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11400:     goto end;
                   11401: 
1.137     brouard  11402:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11403:     nbwarn++;
                   11404:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11405:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11406:   }
1.136     brouard  11407:     /*  if(mle==1){*/
1.137     brouard  11408:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11409:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11410:   }
                   11411: 
                   11412:     /*-calculation of age at interview from date of interview and age at death -*/
                   11413:   agev=matrix(1,maxwav,1,imx);
                   11414: 
                   11415:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11416:     goto end;
                   11417: 
1.126     brouard  11418: 
1.136     brouard  11419:   agegomp=(int)agemin;
                   11420:   free_vector(moisnais,1,n);
                   11421:   free_vector(annais,1,n);
1.126     brouard  11422:   /* free_matrix(mint,1,maxwav,1,n);
                   11423:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11424:   /* free_vector(moisdc,1,n); */
                   11425:   /* free_vector(andc,1,n); */
1.145     brouard  11426:   /* */
                   11427:   
1.126     brouard  11428:   wav=ivector(1,imx);
1.214     brouard  11429:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11430:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11431:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11432:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11433:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11434:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11435:    
                   11436:   /* Concatenates waves */
1.214     brouard  11437:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11438:      Death is a valid wave (if date is known).
                   11439:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11440:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11441:      and mw[mi+1][i]. dh depends on stepm.
                   11442:   */
                   11443: 
1.126     brouard  11444:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11445:   /* Concatenates waves */
1.145     brouard  11446:  
1.215     brouard  11447:   free_vector(moisdc,1,n);
                   11448:   free_vector(andc,1,n);
                   11449: 
1.126     brouard  11450:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11451:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11452:   ncodemax[1]=1;
1.145     brouard  11453:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11454:   cptcoveff=0;
1.220     brouard  11455:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11456:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11457:   }
                   11458:   
                   11459:   ncovcombmax=pow(2,cptcoveff);
                   11460:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11461:   for(i=1;i<ncovcombmax;i++)
                   11462:     invalidvarcomb[i]=0;
                   11463:   
1.211     brouard  11464:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11465:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11466:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11467:   
1.200     brouard  11468:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11469:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11470:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11471:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11472:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11473:    * (currently 0 or 1) in the data.
                   11474:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11475:    * corresponding modality (h,j).
                   11476:    */
                   11477: 
1.145     brouard  11478:   h=0;
                   11479:   /*if (cptcovn > 0) */
1.126     brouard  11480:   m=pow(2,cptcoveff);
                   11481:  
1.144     brouard  11482:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11483:           * For k=4 covariates, h goes from 1 to m=2**k
                   11484:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11485:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11486:           *     h\k   1     2     3     4
1.143     brouard  11487:           *______________________________  
                   11488:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11489:           *     2     2     1     1     1
                   11490:           *     3 i=2 1     2     1     1
                   11491:           *     4     2     2     1     1
                   11492:           *     5 i=3 1 i=2 1     2     1
                   11493:           *     6     2     1     2     1
                   11494:           *     7 i=4 1     2     2     1
                   11495:           *     8     2     2     2     1
1.197     brouard  11496:           *     9 i=5 1 i=3 1 i=2 1     2
                   11497:           *    10     2     1     1     2
                   11498:           *    11 i=6 1     2     1     2
                   11499:           *    12     2     2     1     2
                   11500:           *    13 i=7 1 i=4 1     2     2    
                   11501:           *    14     2     1     2     2
                   11502:           *    15 i=8 1     2     2     2
                   11503:           *    16     2     2     2     2
1.143     brouard  11504:           */
1.212     brouard  11505:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11506:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11507:      * and the value of each covariate?
                   11508:      * V1=1, V2=1, V3=2, V4=1 ?
                   11509:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11510:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11511:      * In order to get the real value in the data, we use nbcode
                   11512:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11513:      * We are keeping this crazy system in order to be able (in the future?) 
                   11514:      * to have more than 2 values (0 or 1) for a covariate.
                   11515:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11516:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11517:      *              bbbbbbbb
                   11518:      *              76543210     
                   11519:      *   h-1        00000101 (6-1=5)
1.219     brouard  11520:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11521:      *           &
                   11522:      *     1        00000001 (1)
1.219     brouard  11523:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11524:      *          +1= 00000001 =1 
1.211     brouard  11525:      *
                   11526:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11527:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11528:      *    >>k'            11
                   11529:      *          &   00000001
                   11530:      *            = 00000001
                   11531:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11532:      * Reverse h=6 and m=16?
                   11533:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11534:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11535:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11536:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11537:      * V3=decodtabm(14,3,2**4)=2
                   11538:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11539:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11540:      *          &1 000000001
                   11541:      *           = 000000001
                   11542:      *         +1= 000000010 =2
                   11543:      *                  2211
                   11544:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11545:      *                  V3=2
1.220     brouard  11546:                 * codtabm and decodtabm are identical
1.211     brouard  11547:      */
                   11548: 
1.145     brouard  11549: 
                   11550:  free_ivector(Ndum,-1,NCOVMAX);
                   11551: 
                   11552: 
1.126     brouard  11553:     
1.186     brouard  11554:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11555:   strcpy(optionfilegnuplot,optionfilefiname);
                   11556:   if(mle==-3)
1.201     brouard  11557:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11558:   strcat(optionfilegnuplot,".gp");
                   11559: 
                   11560:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11561:     printf("Problem with file %s",optionfilegnuplot);
                   11562:   }
                   11563:   else{
1.204     brouard  11564:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11565:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11566:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11567:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11568:   }
                   11569:   /*  fclose(ficgp);*/
1.186     brouard  11570: 
                   11571: 
                   11572:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11573: 
                   11574:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11575:   if(mle==-3)
1.201     brouard  11576:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11577:   strcat(optionfilehtm,".htm");
                   11578:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11579:     printf("Problem with %s \n",optionfilehtm);
                   11580:     exit(0);
1.126     brouard  11581:   }
                   11582: 
                   11583:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11584:   strcat(optionfilehtmcov,"-cov.htm");
                   11585:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11586:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11587:   }
                   11588:   else{
                   11589:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11590: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11591: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11592:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11593:   }
                   11594: 
1.213     brouard  11595:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11596: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11597: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11598: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11599: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11600: \n\
                   11601: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11602:  <ul><li><h4>Parameter files</h4>\n\
                   11603:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11604:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11605:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11606:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11607:  - Date and time at start: %s</ul>\n",\
                   11608:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11609:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11610:          fileres,fileres,\
                   11611:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11612:   fflush(fichtm);
                   11613: 
                   11614:   strcpy(pathr,path);
                   11615:   strcat(pathr,optionfilefiname);
1.184     brouard  11616: #ifdef WIN32
                   11617:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11618: #else
1.126     brouard  11619:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11620: #endif
                   11621:          
1.126     brouard  11622:   
1.220     brouard  11623:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11624:                 and for any valid combination of covariates
1.126     brouard  11625:      and prints on file fileres'p'. */
1.251     brouard  11626:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11627:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11628: 
                   11629:   fprintf(fichtm,"\n");
1.274     brouard  11630:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%f \n<li>Interval for the elementary matrix (in month): stepm=%d",\
                   11631:          ftol, stepm);
                   11632:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11633:   ncurrv=1;
                   11634:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11635:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11636:   ncurrv=i;
                   11637:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11638:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11639:   ncurrv=i;
                   11640:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11641:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11642:   ncurrv=i;
                   11643:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11644:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11645:           nlstate, ndeath, maxwav, mle, weightopt);
                   11646: 
                   11647:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11648: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11649: 
                   11650:   
                   11651:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11652: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11653: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11654:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11655:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11656:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11657:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11658:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11659:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11660: 
1.126     brouard  11661:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11662:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11663:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11664: 
                   11665:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11666:   /* For mortality only */
1.126     brouard  11667:   if (mle==-3){
1.136     brouard  11668:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11669:     for(i=1;i<=NDIM;i++)
                   11670:       for(j=1;j<=NDIM;j++)
                   11671:        ximort[i][j]=0.;
1.186     brouard  11672:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11673:     cens=ivector(1,n);
                   11674:     ageexmed=vector(1,n);
                   11675:     agecens=vector(1,n);
                   11676:     dcwave=ivector(1,n);
1.223     brouard  11677:                
1.126     brouard  11678:     for (i=1; i<=imx; i++){
                   11679:       dcwave[i]=-1;
                   11680:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11681:        if (s[m][i]>nlstate) {
                   11682:          dcwave[i]=m;
                   11683:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11684:          break;
                   11685:        }
1.126     brouard  11686:     }
1.226     brouard  11687:     
1.126     brouard  11688:     for (i=1; i<=imx; i++) {
                   11689:       if (wav[i]>0){
1.226     brouard  11690:        ageexmed[i]=agev[mw[1][i]][i];
                   11691:        j=wav[i];
                   11692:        agecens[i]=1.; 
                   11693:        
                   11694:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11695:          agecens[i]=agev[mw[j][i]][i];
                   11696:          cens[i]= 1;
                   11697:        }else if (ageexmed[i]< 1) 
                   11698:          cens[i]= -1;
                   11699:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11700:          cens[i]=0 ;
1.126     brouard  11701:       }
                   11702:       else cens[i]=-1;
                   11703:     }
                   11704:     
                   11705:     for (i=1;i<=NDIM;i++) {
                   11706:       for (j=1;j<=NDIM;j++)
1.226     brouard  11707:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11708:     }
                   11709:     
1.145     brouard  11710:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11711:     /*printf("%lf %lf", p[1], p[2]);*/
                   11712:     
                   11713:     
1.136     brouard  11714: #ifdef GSL
                   11715:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11716: #else
1.126     brouard  11717:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11718: #endif
1.201     brouard  11719:     strcpy(filerespow,"POW-MORT_"); 
                   11720:     strcat(filerespow,fileresu);
1.126     brouard  11721:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11722:       printf("Problem with resultfile: %s\n", filerespow);
                   11723:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11724:     }
1.136     brouard  11725: #ifdef GSL
                   11726:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11727: #else
1.126     brouard  11728:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11729: #endif
1.126     brouard  11730:     /*  for (i=1;i<=nlstate;i++)
                   11731:        for(j=1;j<=nlstate+ndeath;j++)
                   11732:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11733:     */
                   11734:     fprintf(ficrespow,"\n");
1.136     brouard  11735: #ifdef GSL
                   11736:     /* gsl starts here */ 
                   11737:     T = gsl_multimin_fminimizer_nmsimplex;
                   11738:     gsl_multimin_fminimizer *sfm = NULL;
                   11739:     gsl_vector *ss, *x;
                   11740:     gsl_multimin_function minex_func;
                   11741: 
                   11742:     /* Initial vertex size vector */
                   11743:     ss = gsl_vector_alloc (NDIM);
                   11744:     
                   11745:     if (ss == NULL){
                   11746:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11747:     }
                   11748:     /* Set all step sizes to 1 */
                   11749:     gsl_vector_set_all (ss, 0.001);
                   11750: 
                   11751:     /* Starting point */
1.126     brouard  11752:     
1.136     brouard  11753:     x = gsl_vector_alloc (NDIM);
                   11754:     
                   11755:     if (x == NULL){
                   11756:       gsl_vector_free(ss);
                   11757:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11758:     }
                   11759:   
                   11760:     /* Initialize method and iterate */
                   11761:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11762:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11763:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11764:     gsl_vector_set(x, 0, p[1]);
                   11765:     gsl_vector_set(x, 1, p[2]);
                   11766: 
                   11767:     minex_func.f = &gompertz_f;
                   11768:     minex_func.n = NDIM;
                   11769:     minex_func.params = (void *)&p; /* ??? */
                   11770:     
                   11771:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11772:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11773:     
                   11774:     printf("Iterations beginning .....\n\n");
                   11775:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11776: 
                   11777:     iteri=0;
                   11778:     while (rval == GSL_CONTINUE){
                   11779:       iteri++;
                   11780:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11781:       
                   11782:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11783:       fflush(0);
                   11784:       
                   11785:       if (status) 
                   11786:         break;
                   11787:       
                   11788:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11789:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11790:       
                   11791:       if (rval == GSL_SUCCESS)
                   11792:         printf ("converged to a local maximum at\n");
                   11793:       
                   11794:       printf("%5d ", iteri);
                   11795:       for (it = 0; it < NDIM; it++){
                   11796:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11797:       }
                   11798:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11799:     }
                   11800:     
                   11801:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11802:     
                   11803:     gsl_vector_free(x); /* initial values */
                   11804:     gsl_vector_free(ss); /* inital step size */
                   11805:     for (it=0; it<NDIM; it++){
                   11806:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11807:       fprintf(ficrespow," %.12lf", p[it]);
                   11808:     }
                   11809:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11810: #endif
                   11811: #ifdef POWELL
                   11812:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11813: #endif  
1.126     brouard  11814:     fclose(ficrespow);
                   11815:     
1.203     brouard  11816:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11817: 
                   11818:     for(i=1; i <=NDIM; i++)
                   11819:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11820:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11821:     
                   11822:     printf("\nCovariance matrix\n ");
1.203     brouard  11823:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11824:     for(i=1; i <=NDIM; i++) {
                   11825:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11826:                                printf("%f ",matcov[i][j]);
                   11827:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11828:       }
1.203     brouard  11829:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11830:     }
                   11831:     
                   11832:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11833:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11834:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11835:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11836:     }
1.126     brouard  11837:     lsurv=vector(1,AGESUP);
                   11838:     lpop=vector(1,AGESUP);
                   11839:     tpop=vector(1,AGESUP);
                   11840:     lsurv[agegomp]=100000;
                   11841:     
                   11842:     for (k=agegomp;k<=AGESUP;k++) {
                   11843:       agemortsup=k;
                   11844:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11845:     }
                   11846:     
                   11847:     for (k=agegomp;k<agemortsup;k++)
                   11848:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11849:     
                   11850:     for (k=agegomp;k<agemortsup;k++){
                   11851:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11852:       sumlpop=sumlpop+lpop[k];
                   11853:     }
                   11854:     
                   11855:     tpop[agegomp]=sumlpop;
                   11856:     for (k=agegomp;k<(agemortsup-3);k++){
                   11857:       /*  tpop[k+1]=2;*/
                   11858:       tpop[k+1]=tpop[k]-lpop[k];
                   11859:     }
                   11860:     
                   11861:     
                   11862:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11863:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11864:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11865:     
                   11866:     
                   11867:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11868:                ageminpar=50;
                   11869:                agemaxpar=100;
1.194     brouard  11870:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11871:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11872: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11873: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11874:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11875: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11876: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11877:     }else{
                   11878:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11879:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11880:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11881:                }
1.201     brouard  11882:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11883:                     stepm, weightopt,\
                   11884:                     model,imx,p,matcov,agemortsup);
                   11885:     
                   11886:     free_vector(lsurv,1,AGESUP);
                   11887:     free_vector(lpop,1,AGESUP);
                   11888:     free_vector(tpop,1,AGESUP);
1.220     brouard  11889:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11890:     free_ivector(cens,1,n);
                   11891:     free_vector(agecens,1,n);
                   11892:     free_ivector(dcwave,1,n);
1.220     brouard  11893: #ifdef GSL
1.136     brouard  11894: #endif
1.186     brouard  11895:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11896:   /* Standard  */
                   11897:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11898:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11899:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11900:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11901:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11902:     for (k=1; k<=npar;k++)
                   11903:       printf(" %d %8.5f",k,p[k]);
                   11904:     printf("\n");
1.205     brouard  11905:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11906:       /* mlikeli uses func not funcone */
1.247     brouard  11907:       /* for(i=1;i<nlstate;i++){ */
                   11908:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11909:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11910:       /* } */
1.205     brouard  11911:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11912:     }
                   11913:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11914:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11915:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11916:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11917:     }
                   11918:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11919:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11920:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11921:     for (k=1; k<=npar;k++)
                   11922:       printf(" %d %8.5f",k,p[k]);
                   11923:     printf("\n");
                   11924:     
                   11925:     /*--------- results files --------------*/
1.283     brouard  11926:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11927:     
                   11928:     
                   11929:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11930:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11931:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11932:     for(i=1,jk=1; i <=nlstate; i++){
                   11933:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11934:        if (k != i) {
                   11935:          printf("%d%d ",i,k);
                   11936:          fprintf(ficlog,"%d%d ",i,k);
                   11937:          fprintf(ficres,"%1d%1d ",i,k);
                   11938:          for(j=1; j <=ncovmodel; j++){
                   11939:            printf("%12.7f ",p[jk]);
                   11940:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11941:            fprintf(ficres,"%12.7f ",p[jk]);
                   11942:            jk++; 
                   11943:          }
                   11944:          printf("\n");
                   11945:          fprintf(ficlog,"\n");
                   11946:          fprintf(ficres,"\n");
                   11947:        }
1.126     brouard  11948:       }
                   11949:     }
1.203     brouard  11950:     if(mle != 0){
                   11951:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11952:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11953:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11954:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11955:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11956:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11957:        for(k=1; k <=(nlstate+ndeath); k++){
                   11958:          if (k != i) {
                   11959:            printf("%d%d ",i,k);
                   11960:            fprintf(ficlog,"%d%d ",i,k);
                   11961:            for(j=1; j <=ncovmodel; j++){
                   11962:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11963:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11964:              jk++; 
                   11965:            }
                   11966:            printf("\n");
                   11967:            fprintf(ficlog,"\n");
                   11968:          }
                   11969:        }
1.193     brouard  11970:       }
1.203     brouard  11971:     } /* end of hesscov and Wald tests */
1.225     brouard  11972:     
1.203     brouard  11973:     /*  */
1.126     brouard  11974:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11975:     printf("# Scales (for hessian or gradient estimation)\n");
                   11976:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11977:     for(i=1,jk=1; i <=nlstate; i++){
                   11978:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11979:        if (j!=i) {
                   11980:          fprintf(ficres,"%1d%1d",i,j);
                   11981:          printf("%1d%1d",i,j);
                   11982:          fprintf(ficlog,"%1d%1d",i,j);
                   11983:          for(k=1; k<=ncovmodel;k++){
                   11984:            printf(" %.5e",delti[jk]);
                   11985:            fprintf(ficlog," %.5e",delti[jk]);
                   11986:            fprintf(ficres," %.5e",delti[jk]);
                   11987:            jk++;
                   11988:          }
                   11989:          printf("\n");
                   11990:          fprintf(ficlog,"\n");
                   11991:          fprintf(ficres,"\n");
                   11992:        }
1.126     brouard  11993:       }
                   11994:     }
                   11995:     
                   11996:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11997:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11998:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11999:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12000:     /* # 121 Var(a12)\n\ */
                   12001:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12002:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12003:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12004:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12005:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12006:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12007:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12008:     
                   12009:     
                   12010:     /* Just to have a covariance matrix which will be more understandable
                   12011:        even is we still don't want to manage dictionary of variables
                   12012:     */
                   12013:     for(itimes=1;itimes<=2;itimes++){
                   12014:       jj=0;
                   12015:       for(i=1; i <=nlstate; i++){
1.225     brouard  12016:        for(j=1; j <=nlstate+ndeath; j++){
                   12017:          if(j==i) continue;
                   12018:          for(k=1; k<=ncovmodel;k++){
                   12019:            jj++;
                   12020:            ca[0]= k+'a'-1;ca[1]='\0';
                   12021:            if(itimes==1){
                   12022:              if(mle>=1)
                   12023:                printf("#%1d%1d%d",i,j,k);
                   12024:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12025:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12026:            }else{
                   12027:              if(mle>=1)
                   12028:                printf("%1d%1d%d",i,j,k);
                   12029:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12030:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12031:            }
                   12032:            ll=0;
                   12033:            for(li=1;li <=nlstate; li++){
                   12034:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12035:                if(lj==li) continue;
                   12036:                for(lk=1;lk<=ncovmodel;lk++){
                   12037:                  ll++;
                   12038:                  if(ll<=jj){
                   12039:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12040:                    if(ll<jj){
                   12041:                      if(itimes==1){
                   12042:                        if(mle>=1)
                   12043:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12044:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12045:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12046:                      }else{
                   12047:                        if(mle>=1)
                   12048:                          printf(" %.5e",matcov[jj][ll]); 
                   12049:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12050:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12051:                      }
                   12052:                    }else{
                   12053:                      if(itimes==1){
                   12054:                        if(mle>=1)
                   12055:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12056:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12057:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12058:                      }else{
                   12059:                        if(mle>=1)
                   12060:                          printf(" %.7e",matcov[jj][ll]); 
                   12061:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12062:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12063:                      }
                   12064:                    }
                   12065:                  }
                   12066:                } /* end lk */
                   12067:              } /* end lj */
                   12068:            } /* end li */
                   12069:            if(mle>=1)
                   12070:              printf("\n");
                   12071:            fprintf(ficlog,"\n");
                   12072:            fprintf(ficres,"\n");
                   12073:            numlinepar++;
                   12074:          } /* end k*/
                   12075:        } /*end j */
1.126     brouard  12076:       } /* end i */
                   12077:     } /* end itimes */
                   12078:     
                   12079:     fflush(ficlog);
                   12080:     fflush(ficres);
1.225     brouard  12081:     while(fgets(line, MAXLINE, ficpar)) {
                   12082:       /* If line starts with a # it is a comment */
                   12083:       if (line[0] == '#') {
                   12084:        numlinepar++;
                   12085:        fputs(line,stdout);
                   12086:        fputs(line,ficparo);
                   12087:        fputs(line,ficlog);
                   12088:        continue;
                   12089:       }else
                   12090:        break;
                   12091:     }
                   12092:     
1.209     brouard  12093:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12094:     /*   ungetc(c,ficpar); */
                   12095:     /*   fgets(line, MAXLINE, ficpar); */
                   12096:     /*   fputs(line,stdout); */
                   12097:     /*   fputs(line,ficparo); */
                   12098:     /* } */
                   12099:     /* ungetc(c,ficpar); */
1.126     brouard  12100:     
                   12101:     estepm=0;
1.209     brouard  12102:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12103:       
                   12104:       if (num_filled != 6) {
                   12105:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12106:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12107:        goto end;
                   12108:       }
                   12109:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12110:     }
                   12111:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12112:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12113:     
1.209     brouard  12114:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12115:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12116:     if (fage <= 2) {
                   12117:       bage = ageminpar;
                   12118:       fage = agemaxpar;
                   12119:     }
                   12120:     
                   12121:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12122:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12123:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12124:                
1.186     brouard  12125:     /* Other stuffs, more or less useful */    
1.254     brouard  12126:     while(fgets(line, MAXLINE, ficpar)) {
                   12127:       /* If line starts with a # it is a comment */
                   12128:       if (line[0] == '#') {
                   12129:        numlinepar++;
                   12130:        fputs(line,stdout);
                   12131:        fputs(line,ficparo);
                   12132:        fputs(line,ficlog);
                   12133:        continue;
                   12134:       }else
                   12135:        break;
                   12136:     }
                   12137: 
                   12138:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12139:       
                   12140:       if (num_filled != 7) {
                   12141:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12142:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12143:        goto end;
                   12144:       }
                   12145:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12146:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12147:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12148:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12149:     }
1.254     brouard  12150: 
                   12151:     while(fgets(line, MAXLINE, ficpar)) {
                   12152:       /* If line starts with a # it is a comment */
                   12153:       if (line[0] == '#') {
                   12154:        numlinepar++;
                   12155:        fputs(line,stdout);
                   12156:        fputs(line,ficparo);
                   12157:        fputs(line,ficlog);
                   12158:        continue;
                   12159:       }else
                   12160:        break;
1.126     brouard  12161:     }
                   12162:     
                   12163:     
                   12164:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12165:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12166:     
1.254     brouard  12167:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12168:       if (num_filled != 1) {
                   12169:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12170:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12171:        goto end;
                   12172:       }
                   12173:       printf("pop_based=%d\n",popbased);
                   12174:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12175:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12176:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12177:     }
                   12178:      
1.258     brouard  12179:     /* Results */
                   12180:     nresult=0;
                   12181:     do{
                   12182:       if(!fgets(line, MAXLINE, ficpar)){
                   12183:        endishere=1;
                   12184:        parameterline=14;
                   12185:       }else if (line[0] == '#') {
                   12186:        /* If line starts with a # it is a comment */
1.254     brouard  12187:        numlinepar++;
                   12188:        fputs(line,stdout);
                   12189:        fputs(line,ficparo);
                   12190:        fputs(line,ficlog);
                   12191:        continue;
1.258     brouard  12192:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12193:        parameterline=11;
                   12194:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12195:        parameterline=12;
                   12196:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12197:        parameterline=13;
                   12198:       else{
                   12199:        parameterline=14;
1.254     brouard  12200:       }
1.258     brouard  12201:       switch (parameterline){ 
                   12202:       case 11:
                   12203:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12204:          if (num_filled != 8) {
                   12205:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12206:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12207:            goto end;
                   12208:          }
                   12209:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12210:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12211:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12212:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12213:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12214:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12215:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12216: 
1.258     brouard  12217:        }
1.254     brouard  12218:        break;
1.258     brouard  12219:       case 12:
                   12220:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12221:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12222:          if (num_filled != 8) {
1.262     brouard  12223:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12224:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12225:            goto end;
                   12226:          }
                   12227:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12228:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12229:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12230:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12231:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12232:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12233:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12234:        }
1.230     brouard  12235:        break;
1.258     brouard  12236:       case 13:
                   12237:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12238:          if (num_filled == 0){
                   12239:            resultline[0]='\0';
                   12240:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12241:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12242:            break;
                   12243:          } else if (num_filled != 1){
                   12244:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12245:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12246:          }
                   12247:          nresult++; /* Sum of resultlines */
                   12248:          printf("Result %d: result=%s\n",nresult, resultline);
                   12249:          if(nresult > MAXRESULTLINES){
                   12250:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12251:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12252:            goto end;
                   12253:          }
                   12254:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12255:          fprintf(ficparo,"result: %s\n",resultline);
                   12256:          fprintf(ficres,"result: %s\n",resultline);
                   12257:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12258:          break;
1.258     brouard  12259:        case 14: 
1.259     brouard  12260:          if(ncovmodel >2 && nresult==0 ){
                   12261:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12262:            goto end;
                   12263:          }
1.259     brouard  12264:          break;
1.258     brouard  12265:        default:
                   12266:          nresult=1;
                   12267:          decoderesult(".",nresult ); /* No covariate */
                   12268:        }
                   12269:       } /* End switch parameterline */
                   12270:     }while(endishere==0); /* End do */
1.126     brouard  12271:     
1.230     brouard  12272:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12273:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12274:     
                   12275:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12276:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12277:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12278: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12279: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12280:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12281: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12282: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12283:     }else{
1.270     brouard  12284:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12285:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12286:     }
                   12287:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12288:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12289:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12290:                
1.225     brouard  12291:     /*------------ free_vector  -------------*/
                   12292:     /*  chdir(path); */
1.220     brouard  12293:                
1.215     brouard  12294:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12295:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12296:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12297:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12298:     free_lvector(num,1,n);
                   12299:     free_vector(agedc,1,n);
                   12300:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12301:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12302:     fclose(ficparo);
                   12303:     fclose(ficres);
1.220     brouard  12304:                
                   12305:                
1.186     brouard  12306:     /* Other results (useful)*/
1.220     brouard  12307:                
                   12308:                
1.126     brouard  12309:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12310:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12311:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12312:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12313:     fclose(ficrespl);
                   12314: 
                   12315:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12316:     /*#include "hpijx.h"*/
                   12317:     hPijx(p, bage, fage);
1.145     brouard  12318:     fclose(ficrespij);
1.227     brouard  12319:     
1.220     brouard  12320:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12321:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12322:     k=1;
1.126     brouard  12323:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12324:     
1.269     brouard  12325:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12326:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12327:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12328:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12329:        for(k=1;k<=ncovcombmax;k++)
                   12330:          probs[i][j][k]=0.;
1.269     brouard  12331:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12332:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12333:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12334:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12335:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12336:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12337:          for(k=1;k<=ncovcombmax;k++)
                   12338:            mobaverages[i][j][k]=0.;
1.219     brouard  12339:       mobaverage=mobaverages;
                   12340:       if (mobilav!=0) {
1.235     brouard  12341:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12342:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12343:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12344:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12345:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12346:        }
1.269     brouard  12347:       } else if (mobilavproj !=0) {
1.235     brouard  12348:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12349:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12350:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12351:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12352:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12353:        }
1.269     brouard  12354:       }else{
                   12355:        printf("Internal error moving average\n");
                   12356:        fflush(stdout);
                   12357:        exit(1);
1.219     brouard  12358:       }
                   12359:     }/* end if moving average */
1.227     brouard  12360:     
1.126     brouard  12361:     /*---------- Forecasting ------------------*/
                   12362:     if(prevfcast==1){
                   12363:       /*    if(stepm ==1){*/
1.269     brouard  12364:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12365:     }
1.269     brouard  12366: 
                   12367:     /* Backcasting */
1.217     brouard  12368:     if(backcast==1){
1.219     brouard  12369:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12370:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12371:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12372: 
                   12373:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12374: 
                   12375:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12376: 
1.219     brouard  12377:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12378:       fclose(ficresplb);
                   12379: 
1.222     brouard  12380:       hBijx(p, bage, fage, mobaverage);
                   12381:       fclose(ficrespijb);
1.219     brouard  12382: 
1.269     brouard  12383:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12384:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12385:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12386: 
                   12387:       
1.269     brouard  12388:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12389:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12390:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12391:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12392:     }    /* end  Backcasting */
1.268     brouard  12393:  
1.186     brouard  12394:  
                   12395:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12396: 
1.215     brouard  12397:     free_ivector(wav,1,imx);
                   12398:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12399:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12400:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12401:                
                   12402:                
1.127     brouard  12403:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12404:                
1.201     brouard  12405:     strcpy(filerese,"E_");
                   12406:     strcat(filerese,fileresu);
1.126     brouard  12407:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12408:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12409:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12410:     }
1.208     brouard  12411:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12412:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12413: 
                   12414:     pstamp(ficreseij);
1.219     brouard  12415:                
1.235     brouard  12416:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12417:     if (cptcovn < 1){i1=1;}
                   12418:     
                   12419:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12420:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12421:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12422:        continue;
1.219     brouard  12423:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12424:       printf("\n#****** ");
1.225     brouard  12425:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12426:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12427:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12428:       }
                   12429:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12430:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12431:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12432:       }
                   12433:       fprintf(ficreseij,"******\n");
1.235     brouard  12434:       printf("******\n");
1.219     brouard  12435:       
                   12436:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12437:       oldm=oldms;savm=savms;
1.235     brouard  12438:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12439:       
1.219     brouard  12440:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12441:     }
                   12442:     fclose(ficreseij);
1.208     brouard  12443:     printf("done evsij\n");fflush(stdout);
                   12444:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12445: 
1.218     brouard  12446:                
1.227     brouard  12447:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12448:                
1.201     brouard  12449:     strcpy(filerest,"T_");
                   12450:     strcat(filerest,fileresu);
1.127     brouard  12451:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12452:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12453:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12454:     }
1.208     brouard  12455:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12456:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12457:     strcpy(fileresstde,"STDE_");
                   12458:     strcat(fileresstde,fileresu);
1.126     brouard  12459:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12460:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12461:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12462:     }
1.227     brouard  12463:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12464:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12465: 
1.201     brouard  12466:     strcpy(filerescve,"CVE_");
                   12467:     strcat(filerescve,fileresu);
1.126     brouard  12468:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12469:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12470:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12471:     }
1.227     brouard  12472:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12473:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12474: 
1.201     brouard  12475:     strcpy(fileresv,"V_");
                   12476:     strcat(fileresv,fileresu);
1.126     brouard  12477:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12478:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12479:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12480:     }
1.227     brouard  12481:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12482:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12483: 
1.235     brouard  12484:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12485:     if (cptcovn < 1){i1=1;}
                   12486:     
                   12487:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12488:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12489:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12490:        continue;
1.242     brouard  12491:       printf("\n#****** Result for:");
                   12492:       fprintf(ficrest,"\n#****** Result for:");
                   12493:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12494:       for(j=1;j<=cptcoveff;j++){ 
                   12495:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12496:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12497:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12498:       }
1.235     brouard  12499:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12500:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12501:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12502:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12503:       }        
1.208     brouard  12504:       fprintf(ficrest,"******\n");
1.227     brouard  12505:       fprintf(ficlog,"******\n");
                   12506:       printf("******\n");
1.208     brouard  12507:       
                   12508:       fprintf(ficresstdeij,"\n#****** ");
                   12509:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12510:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12511:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12512:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12513:       }
1.235     brouard  12514:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12515:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12516:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12517:       }        
1.208     brouard  12518:       fprintf(ficresstdeij,"******\n");
                   12519:       fprintf(ficrescveij,"******\n");
                   12520:       
                   12521:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12522:       /* pstamp(ficresvij); */
1.225     brouard  12523:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12524:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12525:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12526:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12527:       }        
1.208     brouard  12528:       fprintf(ficresvij,"******\n");
                   12529:       
                   12530:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12531:       oldm=oldms;savm=savms;
1.235     brouard  12532:       printf(" cvevsij ");
                   12533:       fprintf(ficlog, " cvevsij ");
                   12534:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12535:       printf(" end cvevsij \n ");
                   12536:       fprintf(ficlog, " end cvevsij \n ");
                   12537:       
                   12538:       /*
                   12539:        */
                   12540:       /* goto endfree; */
                   12541:       
                   12542:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12543:       pstamp(ficrest);
                   12544:       
1.269     brouard  12545:       epj=vector(1,nlstate+1);
1.208     brouard  12546:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12547:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12548:        cptcod= 0; /* To be deleted */
                   12549:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12550:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12551:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12552:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12553:        if(vpopbased==1)
                   12554:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12555:        else
                   12556:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12557:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12558:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12559:        fprintf(ficrest,"\n");
                   12560:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12561:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12562:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12563:        for(age=bage; age <=fage ;age++){
1.235     brouard  12564:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12565:          if (vpopbased==1) {
                   12566:            if(mobilav ==0){
                   12567:              for(i=1; i<=nlstate;i++)
                   12568:                prlim[i][i]=probs[(int)age][i][k];
                   12569:            }else{ /* mobilav */ 
                   12570:              for(i=1; i<=nlstate;i++)
                   12571:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12572:            }
                   12573:          }
1.219     brouard  12574:          
1.227     brouard  12575:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12576:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12577:          /* printf(" age %4.0f ",age); */
                   12578:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12579:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12580:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12581:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12582:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12583:            }
                   12584:            epj[nlstate+1] +=epj[j];
                   12585:          }
                   12586:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12587:          
1.227     brouard  12588:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12589:            for(j=1;j <=nlstate;j++)
                   12590:              vepp += vareij[i][j][(int)age];
                   12591:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12592:          for(j=1;j <=nlstate;j++){
                   12593:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12594:          }
                   12595:          fprintf(ficrest,"\n");
                   12596:        }
1.208     brouard  12597:       } /* End vpopbased */
1.269     brouard  12598:       free_vector(epj,1,nlstate+1);
1.208     brouard  12599:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12600:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12601:       printf("done selection\n");fflush(stdout);
                   12602:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12603:       
1.235     brouard  12604:     } /* End k selection */
1.227     brouard  12605: 
                   12606:     printf("done State-specific expectancies\n");fflush(stdout);
                   12607:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12608: 
1.269     brouard  12609:     /* variance-covariance of period prevalence*/
                   12610:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12611: 
1.227     brouard  12612:     
                   12613:     free_vector(weight,1,n);
                   12614:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12615:     free_imatrix(s,1,maxwav+1,1,n);
                   12616:     free_matrix(anint,1,maxwav,1,n); 
                   12617:     free_matrix(mint,1,maxwav,1,n);
                   12618:     free_ivector(cod,1,n);
                   12619:     free_ivector(tab,1,NCOVMAX);
                   12620:     fclose(ficresstdeij);
                   12621:     fclose(ficrescveij);
                   12622:     fclose(ficresvij);
                   12623:     fclose(ficrest);
                   12624:     fclose(ficpar);
                   12625:     
                   12626:     
1.126     brouard  12627:     /*---------- End : free ----------------*/
1.219     brouard  12628:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12629:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12630:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12631:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12632:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12633:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12634:   /* endfree:*/
                   12635:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12636:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12637:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12638:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12639:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12640:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12641:   free_matrix(covar,0,NCOVMAX,1,n);
                   12642:   free_matrix(matcov,1,npar,1,npar);
                   12643:   free_matrix(hess,1,npar,1,npar);
                   12644:   /*free_vector(delti,1,npar);*/
                   12645:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12646:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12647:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12648:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12649:   
                   12650:   free_ivector(ncodemax,1,NCOVMAX);
                   12651:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12652:   free_ivector(Dummy,-1,NCOVMAX);
                   12653:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12654:   free_ivector(DummyV,1,NCOVMAX);
                   12655:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12656:   free_ivector(Typevar,-1,NCOVMAX);
                   12657:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12658:   free_ivector(TvarsQ,1,NCOVMAX);
                   12659:   free_ivector(TvarsQind,1,NCOVMAX);
                   12660:   free_ivector(TvarsD,1,NCOVMAX);
                   12661:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12662:   free_ivector(TvarFD,1,NCOVMAX);
                   12663:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12664:   free_ivector(TvarF,1,NCOVMAX);
                   12665:   free_ivector(TvarFind,1,NCOVMAX);
                   12666:   free_ivector(TvarV,1,NCOVMAX);
                   12667:   free_ivector(TvarVind,1,NCOVMAX);
                   12668:   free_ivector(TvarA,1,NCOVMAX);
                   12669:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12670:   free_ivector(TvarFQ,1,NCOVMAX);
                   12671:   free_ivector(TvarFQind,1,NCOVMAX);
                   12672:   free_ivector(TvarVD,1,NCOVMAX);
                   12673:   free_ivector(TvarVDind,1,NCOVMAX);
                   12674:   free_ivector(TvarVQ,1,NCOVMAX);
                   12675:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12676:   free_ivector(Tvarsel,1,NCOVMAX);
                   12677:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12678:   free_ivector(Tposprod,1,NCOVMAX);
                   12679:   free_ivector(Tprod,1,NCOVMAX);
                   12680:   free_ivector(Tvaraff,1,NCOVMAX);
                   12681:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12682:   free_ivector(Tage,1,NCOVMAX);
                   12683:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12684:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12685:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12686:   
                   12687:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12688:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12689:   fflush(fichtm);
                   12690:   fflush(ficgp);
                   12691:   
1.227     brouard  12692:   
1.126     brouard  12693:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12694:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12695:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12696:   }else{
                   12697:     printf("End of Imach\n");
                   12698:     fprintf(ficlog,"End of Imach\n");
                   12699:   }
                   12700:   printf("See log file on %s\n",filelog);
                   12701:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12702:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12703:   rend_time = time(NULL);  
                   12704:   end_time = *localtime(&rend_time);
                   12705:   /* tml = *localtime(&end_time.tm_sec); */
                   12706:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12707:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12708:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12709:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12710:   
1.157     brouard  12711:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12712:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12713:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12714:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12715: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12716:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12717:   fclose(fichtm);
                   12718:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12719:   fclose(fichtmcov);
                   12720:   fclose(ficgp);
                   12721:   fclose(ficlog);
                   12722:   /*------ End -----------*/
1.227     brouard  12723:   
1.281     brouard  12724: 
                   12725: /* Executes gnuplot */
1.227     brouard  12726:   
                   12727:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12728: #ifdef WIN32
1.227     brouard  12729:   if (_chdir(pathcd) != 0)
                   12730:     printf("Can't move to directory %s!\n",path);
                   12731:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12732: #else
1.227     brouard  12733:     if(chdir(pathcd) != 0)
                   12734:       printf("Can't move to directory %s!\n", path);
                   12735:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12736: #endif 
1.126     brouard  12737:     printf("Current directory %s!\n",pathcd);
                   12738:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12739:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12740: #ifdef _WIN32
1.126     brouard  12741:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12742: #endif
                   12743:   if(!stat(plotcmd,&info)){
1.158     brouard  12744:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12745:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12746:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12747:     }else
                   12748:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12749: #ifdef __unix
1.126     brouard  12750:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12751:     if(!stat(plotcmd,&info)){
1.158     brouard  12752:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12753:     }else
                   12754:       strcpy(pplotcmd,plotcmd);
                   12755: #endif
                   12756:   }else
                   12757:     strcpy(pplotcmd,plotcmd);
                   12758:   
                   12759:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12760:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12761:   
1.126     brouard  12762:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12763:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12764:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12765:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12766:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12767:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12768:   }
1.158     brouard  12769:   printf(" Successful, please wait...");
1.126     brouard  12770:   while (z[0] != 'q') {
                   12771:     /* chdir(path); */
1.154     brouard  12772:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12773:     scanf("%s",z);
                   12774: /*     if (z[0] == 'c') system("./imach"); */
                   12775:     if (z[0] == 'e') {
1.158     brouard  12776: #ifdef __APPLE__
1.152     brouard  12777:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12778: #elif __linux
                   12779:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12780: #else
1.152     brouard  12781:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12782: #endif
                   12783:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12784:       system(pplotcmd);
1.126     brouard  12785:     }
                   12786:     else if (z[0] == 'g') system(plotcmd);
                   12787:     else if (z[0] == 'q') exit(0);
                   12788:   }
1.227     brouard  12789: end:
1.126     brouard  12790:   while (z[0] != 'q') {
1.195     brouard  12791:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12792:     scanf("%s",z);
                   12793:   }
1.283     brouard  12794:   printf("End\n");
1.282     brouard  12795:   exit(0);
1.126     brouard  12796: }

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