Annotation of imach/src/imach.c, revision 1.285

1.285   ! brouard     1: /* $Id: imach.c,v 1.284 2018/04/20 05:22:13 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.285   ! brouard     4:   Revision 1.284  2018/04/20 05:22:13  brouard
        !             5:   Summary: Computing mean and stdeviation of fixed quantitative variables
        !             6: 
1.284     brouard     7:   Revision 1.283  2018/04/19 14:49:16  brouard
                      8:   Summary: Some minor bugs fixed
                      9: 
1.283     brouard    10:   Revision 1.282  2018/02/27 22:50:02  brouard
                     11:   *** empty log message ***
                     12: 
1.282     brouard    13:   Revision 1.281  2018/02/27 19:25:23  brouard
                     14:   Summary: Adding second argument for quitting
                     15: 
1.281     brouard    16:   Revision 1.280  2018/02/21 07:58:13  brouard
                     17:   Summary: 0.99r15
                     18: 
                     19:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     20: 
1.280     brouard    21:   Revision 1.279  2017/07/20 13:35:01  brouard
                     22:   Summary: temporary working
                     23: 
1.279     brouard    24:   Revision 1.278  2017/07/19 14:09:02  brouard
                     25:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     26: 
1.278     brouard    27:   Revision 1.277  2017/07/17 08:53:49  brouard
                     28:   Summary: BOM files can be read now
                     29: 
1.277     brouard    30:   Revision 1.276  2017/06/30 15:48:31  brouard
                     31:   Summary: Graphs improvements
                     32: 
1.276     brouard    33:   Revision 1.275  2017/06/30 13:39:33  brouard
                     34:   Summary: Saito's color
                     35: 
1.275     brouard    36:   Revision 1.274  2017/06/29 09:47:08  brouard
                     37:   Summary: Version 0.99r14
                     38: 
1.274     brouard    39:   Revision 1.273  2017/06/27 11:06:02  brouard
                     40:   Summary: More documentation on projections
                     41: 
1.273     brouard    42:   Revision 1.272  2017/06/27 10:22:40  brouard
                     43:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     44: 
1.272     brouard    45:   Revision 1.271  2017/06/27 10:17:50  brouard
                     46:   Summary: Some bug with rint
                     47: 
1.271     brouard    48:   Revision 1.270  2017/05/24 05:45:29  brouard
                     49:   *** empty log message ***
                     50: 
1.270     brouard    51:   Revision 1.269  2017/05/23 08:39:25  brouard
                     52:   Summary: Code into subroutine, cleanings
                     53: 
1.269     brouard    54:   Revision 1.268  2017/05/18 20:09:32  brouard
                     55:   Summary: backprojection and confidence intervals of backprevalence
                     56: 
1.268     brouard    57:   Revision 1.267  2017/05/13 10:25:05  brouard
                     58:   Summary: temporary save for backprojection
                     59: 
1.267     brouard    60:   Revision 1.266  2017/05/13 07:26:12  brouard
                     61:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     62: 
1.266     brouard    63:   Revision 1.265  2017/04/26 16:22:11  brouard
                     64:   Summary: imach 0.99r13 Some bugs fixed
                     65: 
1.265     brouard    66:   Revision 1.264  2017/04/26 06:01:29  brouard
                     67:   Summary: Labels in graphs
                     68: 
1.264     brouard    69:   Revision 1.263  2017/04/24 15:23:15  brouard
                     70:   Summary: to save
                     71: 
1.263     brouard    72:   Revision 1.262  2017/04/18 16:48:12  brouard
                     73:   *** empty log message ***
                     74: 
1.262     brouard    75:   Revision 1.261  2017/04/05 10:14:09  brouard
                     76:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     77: 
1.261     brouard    78:   Revision 1.260  2017/04/04 17:46:59  brouard
                     79:   Summary: Gnuplot indexations fixed (humm)
                     80: 
1.260     brouard    81:   Revision 1.259  2017/04/04 13:01:16  brouard
                     82:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     83: 
1.259     brouard    84:   Revision 1.258  2017/04/03 10:17:47  brouard
                     85:   Summary: Version 0.99r12
                     86: 
                     87:   Some cleanings, conformed with updated documentation.
                     88: 
1.258     brouard    89:   Revision 1.257  2017/03/29 16:53:30  brouard
                     90:   Summary: Temp
                     91: 
1.257     brouard    92:   Revision 1.256  2017/03/27 05:50:23  brouard
                     93:   Summary: Temporary
                     94: 
1.256     brouard    95:   Revision 1.255  2017/03/08 16:02:28  brouard
                     96:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     97: 
1.255     brouard    98:   Revision 1.254  2017/03/08 07:13:00  brouard
                     99:   Summary: Fixing data parameter line
                    100: 
1.254     brouard   101:   Revision 1.253  2016/12/15 11:59:41  brouard
                    102:   Summary: 0.99 in progress
                    103: 
1.253     brouard   104:   Revision 1.252  2016/09/15 21:15:37  brouard
                    105:   *** empty log message ***
                    106: 
1.252     brouard   107:   Revision 1.251  2016/09/15 15:01:13  brouard
                    108:   Summary: not working
                    109: 
1.251     brouard   110:   Revision 1.250  2016/09/08 16:07:27  brouard
                    111:   Summary: continue
                    112: 
1.250     brouard   113:   Revision 1.249  2016/09/07 17:14:18  brouard
                    114:   Summary: Starting values from frequencies
                    115: 
1.249     brouard   116:   Revision 1.248  2016/09/07 14:10:18  brouard
                    117:   *** empty log message ***
                    118: 
1.248     brouard   119:   Revision 1.247  2016/09/02 11:11:21  brouard
                    120:   *** empty log message ***
                    121: 
1.247     brouard   122:   Revision 1.246  2016/09/02 08:49:22  brouard
                    123:   *** empty log message ***
                    124: 
1.246     brouard   125:   Revision 1.245  2016/09/02 07:25:01  brouard
                    126:   *** empty log message ***
                    127: 
1.245     brouard   128:   Revision 1.244  2016/09/02 07:17:34  brouard
                    129:   *** empty log message ***
                    130: 
1.244     brouard   131:   Revision 1.243  2016/09/02 06:45:35  brouard
                    132:   *** empty log message ***
                    133: 
1.243     brouard   134:   Revision 1.242  2016/08/30 15:01:20  brouard
                    135:   Summary: Fixing a lots
                    136: 
1.242     brouard   137:   Revision 1.241  2016/08/29 17:17:25  brouard
                    138:   Summary: gnuplot problem in Back projection to fix
                    139: 
1.241     brouard   140:   Revision 1.240  2016/08/29 07:53:18  brouard
                    141:   Summary: Better
                    142: 
1.240     brouard   143:   Revision 1.239  2016/08/26 15:51:03  brouard
                    144:   Summary: Improvement in Powell output in order to copy and paste
                    145: 
                    146:   Author:
                    147: 
1.239     brouard   148:   Revision 1.238  2016/08/26 14:23:35  brouard
                    149:   Summary: Starting tests of 0.99
                    150: 
1.238     brouard   151:   Revision 1.237  2016/08/26 09:20:19  brouard
                    152:   Summary: to valgrind
                    153: 
1.237     brouard   154:   Revision 1.236  2016/08/25 10:50:18  brouard
                    155:   *** empty log message ***
                    156: 
1.236     brouard   157:   Revision 1.235  2016/08/25 06:59:23  brouard
                    158:   *** empty log message ***
                    159: 
1.235     brouard   160:   Revision 1.234  2016/08/23 16:51:20  brouard
                    161:   *** empty log message ***
                    162: 
1.234     brouard   163:   Revision 1.233  2016/08/23 07:40:50  brouard
                    164:   Summary: not working
                    165: 
1.233     brouard   166:   Revision 1.232  2016/08/22 14:20:21  brouard
                    167:   Summary: not working
                    168: 
1.232     brouard   169:   Revision 1.231  2016/08/22 07:17:15  brouard
                    170:   Summary: not working
                    171: 
1.231     brouard   172:   Revision 1.230  2016/08/22 06:55:53  brouard
                    173:   Summary: Not working
                    174: 
1.230     brouard   175:   Revision 1.229  2016/07/23 09:45:53  brouard
                    176:   Summary: Completing for func too
                    177: 
1.229     brouard   178:   Revision 1.228  2016/07/22 17:45:30  brouard
                    179:   Summary: Fixing some arrays, still debugging
                    180: 
1.227     brouard   181:   Revision 1.226  2016/07/12 18:42:34  brouard
                    182:   Summary: temp
                    183: 
1.226     brouard   184:   Revision 1.225  2016/07/12 08:40:03  brouard
                    185:   Summary: saving but not running
                    186: 
1.225     brouard   187:   Revision 1.224  2016/07/01 13:16:01  brouard
                    188:   Summary: Fixes
                    189: 
1.224     brouard   190:   Revision 1.223  2016/02/19 09:23:35  brouard
                    191:   Summary: temporary
                    192: 
1.223     brouard   193:   Revision 1.222  2016/02/17 08:14:50  brouard
                    194:   Summary: Probably last 0.98 stable version 0.98r6
                    195: 
1.222     brouard   196:   Revision 1.221  2016/02/15 23:35:36  brouard
                    197:   Summary: minor bug
                    198: 
1.220     brouard   199:   Revision 1.219  2016/02/15 00:48:12  brouard
                    200:   *** empty log message ***
                    201: 
1.219     brouard   202:   Revision 1.218  2016/02/12 11:29:23  brouard
                    203:   Summary: 0.99 Back projections
                    204: 
1.218     brouard   205:   Revision 1.217  2015/12/23 17:18:31  brouard
                    206:   Summary: Experimental backcast
                    207: 
1.217     brouard   208:   Revision 1.216  2015/12/18 17:32:11  brouard
                    209:   Summary: 0.98r4 Warning and status=-2
                    210: 
                    211:   Version 0.98r4 is now:
                    212:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    213:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    214:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    215: 
1.216     brouard   216:   Revision 1.215  2015/12/16 08:52:24  brouard
                    217:   Summary: 0.98r4 working
                    218: 
1.215     brouard   219:   Revision 1.214  2015/12/16 06:57:54  brouard
                    220:   Summary: temporary not working
                    221: 
1.214     brouard   222:   Revision 1.213  2015/12/11 18:22:17  brouard
                    223:   Summary: 0.98r4
                    224: 
1.213     brouard   225:   Revision 1.212  2015/11/21 12:47:24  brouard
                    226:   Summary: minor typo
                    227: 
1.212     brouard   228:   Revision 1.211  2015/11/21 12:41:11  brouard
                    229:   Summary: 0.98r3 with some graph of projected cross-sectional
                    230: 
                    231:   Author: Nicolas Brouard
                    232: 
1.211     brouard   233:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   234:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   235:   Summary: Adding ftolpl parameter
                    236:   Author: N Brouard
                    237: 
                    238:   We had difficulties to get smoothed confidence intervals. It was due
                    239:   to the period prevalence which wasn't computed accurately. The inner
                    240:   parameter ftolpl is now an outer parameter of the .imach parameter
                    241:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    242:   computation are long.
                    243: 
1.209     brouard   244:   Revision 1.208  2015/11/17 14:31:57  brouard
                    245:   Summary: temporary
                    246: 
1.208     brouard   247:   Revision 1.207  2015/10/27 17:36:57  brouard
                    248:   *** empty log message ***
                    249: 
1.207     brouard   250:   Revision 1.206  2015/10/24 07:14:11  brouard
                    251:   *** empty log message ***
                    252: 
1.206     brouard   253:   Revision 1.205  2015/10/23 15:50:53  brouard
                    254:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    255: 
1.205     brouard   256:   Revision 1.204  2015/10/01 16:20:26  brouard
                    257:   Summary: Some new graphs of contribution to likelihood
                    258: 
1.204     brouard   259:   Revision 1.203  2015/09/30 17:45:14  brouard
                    260:   Summary: looking at better estimation of the hessian
                    261: 
                    262:   Also a better criteria for convergence to the period prevalence And
                    263:   therefore adding the number of years needed to converge. (The
                    264:   prevalence in any alive state shold sum to one
                    265: 
1.203     brouard   266:   Revision 1.202  2015/09/22 19:45:16  brouard
                    267:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    268: 
1.202     brouard   269:   Revision 1.201  2015/09/15 17:34:58  brouard
                    270:   Summary: 0.98r0
                    271: 
                    272:   - Some new graphs like suvival functions
                    273:   - Some bugs fixed like model=1+age+V2.
                    274: 
1.201     brouard   275:   Revision 1.200  2015/09/09 16:53:55  brouard
                    276:   Summary: Big bug thanks to Flavia
                    277: 
                    278:   Even model=1+age+V2. did not work anymore
                    279: 
1.200     brouard   280:   Revision 1.199  2015/09/07 14:09:23  brouard
                    281:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    282: 
1.199     brouard   283:   Revision 1.198  2015/09/03 07:14:39  brouard
                    284:   Summary: 0.98q5 Flavia
                    285: 
1.198     brouard   286:   Revision 1.197  2015/09/01 18:24:39  brouard
                    287:   *** empty log message ***
                    288: 
1.197     brouard   289:   Revision 1.196  2015/08/18 23:17:52  brouard
                    290:   Summary: 0.98q5
                    291: 
1.196     brouard   292:   Revision 1.195  2015/08/18 16:28:39  brouard
                    293:   Summary: Adding a hack for testing purpose
                    294: 
                    295:   After reading the title, ftol and model lines, if the comment line has
                    296:   a q, starting with #q, the answer at the end of the run is quit. It
                    297:   permits to run test files in batch with ctest. The former workaround was
                    298:   $ echo q | imach foo.imach
                    299: 
1.195     brouard   300:   Revision 1.194  2015/08/18 13:32:00  brouard
                    301:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    302: 
1.194     brouard   303:   Revision 1.193  2015/08/04 07:17:42  brouard
                    304:   Summary: 0.98q4
                    305: 
1.193     brouard   306:   Revision 1.192  2015/07/16 16:49:02  brouard
                    307:   Summary: Fixing some outputs
                    308: 
1.192     brouard   309:   Revision 1.191  2015/07/14 10:00:33  brouard
                    310:   Summary: Some fixes
                    311: 
1.191     brouard   312:   Revision 1.190  2015/05/05 08:51:13  brouard
                    313:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    314: 
                    315:   Fix 1+age+.
                    316: 
1.190     brouard   317:   Revision 1.189  2015/04/30 14:45:16  brouard
                    318:   Summary: 0.98q2
                    319: 
1.189     brouard   320:   Revision 1.188  2015/04/30 08:27:53  brouard
                    321:   *** empty log message ***
                    322: 
1.188     brouard   323:   Revision 1.187  2015/04/29 09:11:15  brouard
                    324:   *** empty log message ***
                    325: 
1.187     brouard   326:   Revision 1.186  2015/04/23 12:01:52  brouard
                    327:   Summary: V1*age is working now, version 0.98q1
                    328: 
                    329:   Some codes had been disabled in order to simplify and Vn*age was
                    330:   working in the optimization phase, ie, giving correct MLE parameters,
                    331:   but, as usual, outputs were not correct and program core dumped.
                    332: 
1.186     brouard   333:   Revision 1.185  2015/03/11 13:26:42  brouard
                    334:   Summary: Inclusion of compile and links command line for Intel Compiler
                    335: 
1.185     brouard   336:   Revision 1.184  2015/03/11 11:52:39  brouard
                    337:   Summary: Back from Windows 8. Intel Compiler
                    338: 
1.184     brouard   339:   Revision 1.183  2015/03/10 20:34:32  brouard
                    340:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    341: 
                    342:   We use directest instead of original Powell test; probably no
                    343:   incidence on the results, but better justifications;
                    344:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    345:   wrong results.
                    346: 
1.183     brouard   347:   Revision 1.182  2015/02/12 08:19:57  brouard
                    348:   Summary: Trying to keep directest which seems simpler and more general
                    349:   Author: Nicolas Brouard
                    350: 
1.182     brouard   351:   Revision 1.181  2015/02/11 23:22:24  brouard
                    352:   Summary: Comments on Powell added
                    353: 
                    354:   Author:
                    355: 
1.181     brouard   356:   Revision 1.180  2015/02/11 17:33:45  brouard
                    357:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    358: 
1.180     brouard   359:   Revision 1.179  2015/01/04 09:57:06  brouard
                    360:   Summary: back to OS/X
                    361: 
1.179     brouard   362:   Revision 1.178  2015/01/04 09:35:48  brouard
                    363:   *** empty log message ***
                    364: 
1.178     brouard   365:   Revision 1.177  2015/01/03 18:40:56  brouard
                    366:   Summary: Still testing ilc32 on OSX
                    367: 
1.177     brouard   368:   Revision 1.176  2015/01/03 16:45:04  brouard
                    369:   *** empty log message ***
                    370: 
1.176     brouard   371:   Revision 1.175  2015/01/03 16:33:42  brouard
                    372:   *** empty log message ***
                    373: 
1.175     brouard   374:   Revision 1.174  2015/01/03 16:15:49  brouard
                    375:   Summary: Still in cross-compilation
                    376: 
1.174     brouard   377:   Revision 1.173  2015/01/03 12:06:26  brouard
                    378:   Summary: trying to detect cross-compilation
                    379: 
1.173     brouard   380:   Revision 1.172  2014/12/27 12:07:47  brouard
                    381:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    382: 
1.172     brouard   383:   Revision 1.171  2014/12/23 13:26:59  brouard
                    384:   Summary: Back from Visual C
                    385: 
                    386:   Still problem with utsname.h on Windows
                    387: 
1.171     brouard   388:   Revision 1.170  2014/12/23 11:17:12  brouard
                    389:   Summary: Cleaning some \%% back to %%
                    390: 
                    391:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    392: 
1.170     brouard   393:   Revision 1.169  2014/12/22 23:08:31  brouard
                    394:   Summary: 0.98p
                    395: 
                    396:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    397: 
1.169     brouard   398:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   399:   Summary: update
1.169     brouard   400: 
1.168     brouard   401:   Revision 1.167  2014/12/22 13:50:56  brouard
                    402:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    403: 
                    404:   Testing on Linux 64
                    405: 
1.167     brouard   406:   Revision 1.166  2014/12/22 11:40:47  brouard
                    407:   *** empty log message ***
                    408: 
1.166     brouard   409:   Revision 1.165  2014/12/16 11:20:36  brouard
                    410:   Summary: After compiling on Visual C
                    411: 
                    412:   * imach.c (Module): Merging 1.61 to 1.162
                    413: 
1.165     brouard   414:   Revision 1.164  2014/12/16 10:52:11  brouard
                    415:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    416: 
                    417:   * imach.c (Module): Merging 1.61 to 1.162
                    418: 
1.164     brouard   419:   Revision 1.163  2014/12/16 10:30:11  brouard
                    420:   * imach.c (Module): Merging 1.61 to 1.162
                    421: 
1.163     brouard   422:   Revision 1.162  2014/09/25 11:43:39  brouard
                    423:   Summary: temporary backup 0.99!
                    424: 
1.162     brouard   425:   Revision 1.1  2014/09/16 11:06:58  brouard
                    426:   Summary: With some code (wrong) for nlopt
                    427: 
                    428:   Author:
                    429: 
                    430:   Revision 1.161  2014/09/15 20:41:41  brouard
                    431:   Summary: Problem with macro SQR on Intel compiler
                    432: 
1.161     brouard   433:   Revision 1.160  2014/09/02 09:24:05  brouard
                    434:   *** empty log message ***
                    435: 
1.160     brouard   436:   Revision 1.159  2014/09/01 10:34:10  brouard
                    437:   Summary: WIN32
                    438:   Author: Brouard
                    439: 
1.159     brouard   440:   Revision 1.158  2014/08/27 17:11:51  brouard
                    441:   *** empty log message ***
                    442: 
1.158     brouard   443:   Revision 1.157  2014/08/27 16:26:55  brouard
                    444:   Summary: Preparing windows Visual studio version
                    445:   Author: Brouard
                    446: 
                    447:   In order to compile on Visual studio, time.h is now correct and time_t
                    448:   and tm struct should be used. difftime should be used but sometimes I
                    449:   just make the differences in raw time format (time(&now).
                    450:   Trying to suppress #ifdef LINUX
                    451:   Add xdg-open for __linux in order to open default browser.
                    452: 
1.157     brouard   453:   Revision 1.156  2014/08/25 20:10:10  brouard
                    454:   *** empty log message ***
                    455: 
1.156     brouard   456:   Revision 1.155  2014/08/25 18:32:34  brouard
                    457:   Summary: New compile, minor changes
                    458:   Author: Brouard
                    459: 
1.155     brouard   460:   Revision 1.154  2014/06/20 17:32:08  brouard
                    461:   Summary: Outputs now all graphs of convergence to period prevalence
                    462: 
1.154     brouard   463:   Revision 1.153  2014/06/20 16:45:46  brouard
                    464:   Summary: If 3 live state, convergence to period prevalence on same graph
                    465:   Author: Brouard
                    466: 
1.153     brouard   467:   Revision 1.152  2014/06/18 17:54:09  brouard
                    468:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    469: 
1.152     brouard   470:   Revision 1.151  2014/06/18 16:43:30  brouard
                    471:   *** empty log message ***
                    472: 
1.151     brouard   473:   Revision 1.150  2014/06/18 16:42:35  brouard
                    474:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    475:   Author: brouard
                    476: 
1.150     brouard   477:   Revision 1.149  2014/06/18 15:51:14  brouard
                    478:   Summary: Some fixes in parameter files errors
                    479:   Author: Nicolas Brouard
                    480: 
1.149     brouard   481:   Revision 1.148  2014/06/17 17:38:48  brouard
                    482:   Summary: Nothing new
                    483:   Author: Brouard
                    484: 
                    485:   Just a new packaging for OS/X version 0.98nS
                    486: 
1.148     brouard   487:   Revision 1.147  2014/06/16 10:33:11  brouard
                    488:   *** empty log message ***
                    489: 
1.147     brouard   490:   Revision 1.146  2014/06/16 10:20:28  brouard
                    491:   Summary: Merge
                    492:   Author: Brouard
                    493: 
                    494:   Merge, before building revised version.
                    495: 
1.146     brouard   496:   Revision 1.145  2014/06/10 21:23:15  brouard
                    497:   Summary: Debugging with valgrind
                    498:   Author: Nicolas Brouard
                    499: 
                    500:   Lot of changes in order to output the results with some covariates
                    501:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    502:   improve the code.
                    503:   No more memory valgrind error but a lot has to be done in order to
                    504:   continue the work of splitting the code into subroutines.
                    505:   Also, decodemodel has been improved. Tricode is still not
                    506:   optimal. nbcode should be improved. Documentation has been added in
                    507:   the source code.
                    508: 
1.144     brouard   509:   Revision 1.143  2014/01/26 09:45:38  brouard
                    510:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    511: 
                    512:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    513:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    514: 
1.143     brouard   515:   Revision 1.142  2014/01/26 03:57:36  brouard
                    516:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    517: 
                    518:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    519: 
1.142     brouard   520:   Revision 1.141  2014/01/26 02:42:01  brouard
                    521:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    522: 
1.141     brouard   523:   Revision 1.140  2011/09/02 10:37:54  brouard
                    524:   Summary: times.h is ok with mingw32 now.
                    525: 
1.140     brouard   526:   Revision 1.139  2010/06/14 07:50:17  brouard
                    527:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    528:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    529: 
1.139     brouard   530:   Revision 1.138  2010/04/30 18:19:40  brouard
                    531:   *** empty log message ***
                    532: 
1.138     brouard   533:   Revision 1.137  2010/04/29 18:11:38  brouard
                    534:   (Module): Checking covariates for more complex models
                    535:   than V1+V2. A lot of change to be done. Unstable.
                    536: 
1.137     brouard   537:   Revision 1.136  2010/04/26 20:30:53  brouard
                    538:   (Module): merging some libgsl code. Fixing computation
                    539:   of likelione (using inter/intrapolation if mle = 0) in order to
                    540:   get same likelihood as if mle=1.
                    541:   Some cleaning of code and comments added.
                    542: 
1.136     brouard   543:   Revision 1.135  2009/10/29 15:33:14  brouard
                    544:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    545: 
1.135     brouard   546:   Revision 1.134  2009/10/29 13:18:53  brouard
                    547:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    548: 
1.134     brouard   549:   Revision 1.133  2009/07/06 10:21:25  brouard
                    550:   just nforces
                    551: 
1.133     brouard   552:   Revision 1.132  2009/07/06 08:22:05  brouard
                    553:   Many tings
                    554: 
1.132     brouard   555:   Revision 1.131  2009/06/20 16:22:47  brouard
                    556:   Some dimensions resccaled
                    557: 
1.131     brouard   558:   Revision 1.130  2009/05/26 06:44:34  brouard
                    559:   (Module): Max Covariate is now set to 20 instead of 8. A
                    560:   lot of cleaning with variables initialized to 0. Trying to make
                    561:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    562: 
1.130     brouard   563:   Revision 1.129  2007/08/31 13:49:27  lievre
                    564:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    565: 
1.129     lievre    566:   Revision 1.128  2006/06/30 13:02:05  brouard
                    567:   (Module): Clarifications on computing e.j
                    568: 
1.128     brouard   569:   Revision 1.127  2006/04/28 18:11:50  brouard
                    570:   (Module): Yes the sum of survivors was wrong since
                    571:   imach-114 because nhstepm was no more computed in the age
                    572:   loop. Now we define nhstepma in the age loop.
                    573:   (Module): In order to speed up (in case of numerous covariates) we
                    574:   compute health expectancies (without variances) in a first step
                    575:   and then all the health expectancies with variances or standard
                    576:   deviation (needs data from the Hessian matrices) which slows the
                    577:   computation.
                    578:   In the future we should be able to stop the program is only health
                    579:   expectancies and graph are needed without standard deviations.
                    580: 
1.127     brouard   581:   Revision 1.126  2006/04/28 17:23:28  brouard
                    582:   (Module): Yes the sum of survivors was wrong since
                    583:   imach-114 because nhstepm was no more computed in the age
                    584:   loop. Now we define nhstepma in the age loop.
                    585:   Version 0.98h
                    586: 
1.126     brouard   587:   Revision 1.125  2006/04/04 15:20:31  lievre
                    588:   Errors in calculation of health expectancies. Age was not initialized.
                    589:   Forecasting file added.
                    590: 
                    591:   Revision 1.124  2006/03/22 17:13:53  lievre
                    592:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    593:   The log-likelihood is printed in the log file
                    594: 
                    595:   Revision 1.123  2006/03/20 10:52:43  brouard
                    596:   * imach.c (Module): <title> changed, corresponds to .htm file
                    597:   name. <head> headers where missing.
                    598: 
                    599:   * imach.c (Module): Weights can have a decimal point as for
                    600:   English (a comma might work with a correct LC_NUMERIC environment,
                    601:   otherwise the weight is truncated).
                    602:   Modification of warning when the covariates values are not 0 or
                    603:   1.
                    604:   Version 0.98g
                    605: 
                    606:   Revision 1.122  2006/03/20 09:45:41  brouard
                    607:   (Module): Weights can have a decimal point as for
                    608:   English (a comma might work with a correct LC_NUMERIC environment,
                    609:   otherwise the weight is truncated).
                    610:   Modification of warning when the covariates values are not 0 or
                    611:   1.
                    612:   Version 0.98g
                    613: 
                    614:   Revision 1.121  2006/03/16 17:45:01  lievre
                    615:   * imach.c (Module): Comments concerning covariates added
                    616: 
                    617:   * imach.c (Module): refinements in the computation of lli if
                    618:   status=-2 in order to have more reliable computation if stepm is
                    619:   not 1 month. Version 0.98f
                    620: 
                    621:   Revision 1.120  2006/03/16 15:10:38  lievre
                    622:   (Module): refinements in the computation of lli if
                    623:   status=-2 in order to have more reliable computation if stepm is
                    624:   not 1 month. Version 0.98f
                    625: 
                    626:   Revision 1.119  2006/03/15 17:42:26  brouard
                    627:   (Module): Bug if status = -2, the loglikelihood was
                    628:   computed as likelihood omitting the logarithm. Version O.98e
                    629: 
                    630:   Revision 1.118  2006/03/14 18:20:07  brouard
                    631:   (Module): varevsij Comments added explaining the second
                    632:   table of variances if popbased=1 .
                    633:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    634:   (Module): Function pstamp added
                    635:   (Module): Version 0.98d
                    636: 
                    637:   Revision 1.117  2006/03/14 17:16:22  brouard
                    638:   (Module): varevsij Comments added explaining the second
                    639:   table of variances if popbased=1 .
                    640:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    641:   (Module): Function pstamp added
                    642:   (Module): Version 0.98d
                    643: 
                    644:   Revision 1.116  2006/03/06 10:29:27  brouard
                    645:   (Module): Variance-covariance wrong links and
                    646:   varian-covariance of ej. is needed (Saito).
                    647: 
                    648:   Revision 1.115  2006/02/27 12:17:45  brouard
                    649:   (Module): One freematrix added in mlikeli! 0.98c
                    650: 
                    651:   Revision 1.114  2006/02/26 12:57:58  brouard
                    652:   (Module): Some improvements in processing parameter
                    653:   filename with strsep.
                    654: 
                    655:   Revision 1.113  2006/02/24 14:20:24  brouard
                    656:   (Module): Memory leaks checks with valgrind and:
                    657:   datafile was not closed, some imatrix were not freed and on matrix
                    658:   allocation too.
                    659: 
                    660:   Revision 1.112  2006/01/30 09:55:26  brouard
                    661:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    662: 
                    663:   Revision 1.111  2006/01/25 20:38:18  brouard
                    664:   (Module): Lots of cleaning and bugs added (Gompertz)
                    665:   (Module): Comments can be added in data file. Missing date values
                    666:   can be a simple dot '.'.
                    667: 
                    668:   Revision 1.110  2006/01/25 00:51:50  brouard
                    669:   (Module): Lots of cleaning and bugs added (Gompertz)
                    670: 
                    671:   Revision 1.109  2006/01/24 19:37:15  brouard
                    672:   (Module): Comments (lines starting with a #) are allowed in data.
                    673: 
                    674:   Revision 1.108  2006/01/19 18:05:42  lievre
                    675:   Gnuplot problem appeared...
                    676:   To be fixed
                    677: 
                    678:   Revision 1.107  2006/01/19 16:20:37  brouard
                    679:   Test existence of gnuplot in imach path
                    680: 
                    681:   Revision 1.106  2006/01/19 13:24:36  brouard
                    682:   Some cleaning and links added in html output
                    683: 
                    684:   Revision 1.105  2006/01/05 20:23:19  lievre
                    685:   *** empty log message ***
                    686: 
                    687:   Revision 1.104  2005/09/30 16:11:43  lievre
                    688:   (Module): sump fixed, loop imx fixed, and simplifications.
                    689:   (Module): If the status is missing at the last wave but we know
                    690:   that the person is alive, then we can code his/her status as -2
                    691:   (instead of missing=-1 in earlier versions) and his/her
                    692:   contributions to the likelihood is 1 - Prob of dying from last
                    693:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    694:   the healthy state at last known wave). Version is 0.98
                    695: 
                    696:   Revision 1.103  2005/09/30 15:54:49  lievre
                    697:   (Module): sump fixed, loop imx fixed, and simplifications.
                    698: 
                    699:   Revision 1.102  2004/09/15 17:31:30  brouard
                    700:   Add the possibility to read data file including tab characters.
                    701: 
                    702:   Revision 1.101  2004/09/15 10:38:38  brouard
                    703:   Fix on curr_time
                    704: 
                    705:   Revision 1.100  2004/07/12 18:29:06  brouard
                    706:   Add version for Mac OS X. Just define UNIX in Makefile
                    707: 
                    708:   Revision 1.99  2004/06/05 08:57:40  brouard
                    709:   *** empty log message ***
                    710: 
                    711:   Revision 1.98  2004/05/16 15:05:56  brouard
                    712:   New version 0.97 . First attempt to estimate force of mortality
                    713:   directly from the data i.e. without the need of knowing the health
                    714:   state at each age, but using a Gompertz model: log u =a + b*age .
                    715:   This is the basic analysis of mortality and should be done before any
                    716:   other analysis, in order to test if the mortality estimated from the
                    717:   cross-longitudinal survey is different from the mortality estimated
                    718:   from other sources like vital statistic data.
                    719: 
                    720:   The same imach parameter file can be used but the option for mle should be -3.
                    721: 
1.133     brouard   722:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   723:   former routines in order to include the new code within the former code.
                    724: 
                    725:   The output is very simple: only an estimate of the intercept and of
                    726:   the slope with 95% confident intervals.
                    727: 
                    728:   Current limitations:
                    729:   A) Even if you enter covariates, i.e. with the
                    730:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    731:   B) There is no computation of Life Expectancy nor Life Table.
                    732: 
                    733:   Revision 1.97  2004/02/20 13:25:42  lievre
                    734:   Version 0.96d. Population forecasting command line is (temporarily)
                    735:   suppressed.
                    736: 
                    737:   Revision 1.96  2003/07/15 15:38:55  brouard
                    738:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    739:   rewritten within the same printf. Workaround: many printfs.
                    740: 
                    741:   Revision 1.95  2003/07/08 07:54:34  brouard
                    742:   * imach.c (Repository):
                    743:   (Repository): Using imachwizard code to output a more meaningful covariance
                    744:   matrix (cov(a12,c31) instead of numbers.
                    745: 
                    746:   Revision 1.94  2003/06/27 13:00:02  brouard
                    747:   Just cleaning
                    748: 
                    749:   Revision 1.93  2003/06/25 16:33:55  brouard
                    750:   (Module): On windows (cygwin) function asctime_r doesn't
                    751:   exist so I changed back to asctime which exists.
                    752:   (Module): Version 0.96b
                    753: 
                    754:   Revision 1.92  2003/06/25 16:30:45  brouard
                    755:   (Module): On windows (cygwin) function asctime_r doesn't
                    756:   exist so I changed back to asctime which exists.
                    757: 
                    758:   Revision 1.91  2003/06/25 15:30:29  brouard
                    759:   * imach.c (Repository): Duplicated warning errors corrected.
                    760:   (Repository): Elapsed time after each iteration is now output. It
                    761:   helps to forecast when convergence will be reached. Elapsed time
                    762:   is stamped in powell.  We created a new html file for the graphs
                    763:   concerning matrix of covariance. It has extension -cov.htm.
                    764: 
                    765:   Revision 1.90  2003/06/24 12:34:15  brouard
                    766:   (Module): Some bugs corrected for windows. Also, when
                    767:   mle=-1 a template is output in file "or"mypar.txt with the design
                    768:   of the covariance matrix to be input.
                    769: 
                    770:   Revision 1.89  2003/06/24 12:30:52  brouard
                    771:   (Module): Some bugs corrected for windows. Also, when
                    772:   mle=-1 a template is output in file "or"mypar.txt with the design
                    773:   of the covariance matrix to be input.
                    774: 
                    775:   Revision 1.88  2003/06/23 17:54:56  brouard
                    776:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    777: 
                    778:   Revision 1.87  2003/06/18 12:26:01  brouard
                    779:   Version 0.96
                    780: 
                    781:   Revision 1.86  2003/06/17 20:04:08  brouard
                    782:   (Module): Change position of html and gnuplot routines and added
                    783:   routine fileappend.
                    784: 
                    785:   Revision 1.85  2003/06/17 13:12:43  brouard
                    786:   * imach.c (Repository): Check when date of death was earlier that
                    787:   current date of interview. It may happen when the death was just
                    788:   prior to the death. In this case, dh was negative and likelihood
                    789:   was wrong (infinity). We still send an "Error" but patch by
                    790:   assuming that the date of death was just one stepm after the
                    791:   interview.
                    792:   (Repository): Because some people have very long ID (first column)
                    793:   we changed int to long in num[] and we added a new lvector for
                    794:   memory allocation. But we also truncated to 8 characters (left
                    795:   truncation)
                    796:   (Repository): No more line truncation errors.
                    797: 
                    798:   Revision 1.84  2003/06/13 21:44:43  brouard
                    799:   * imach.c (Repository): Replace "freqsummary" at a correct
                    800:   place. It differs from routine "prevalence" which may be called
                    801:   many times. Probs is memory consuming and must be used with
                    802:   parcimony.
                    803:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    804: 
                    805:   Revision 1.83  2003/06/10 13:39:11  lievre
                    806:   *** empty log message ***
                    807: 
                    808:   Revision 1.82  2003/06/05 15:57:20  brouard
                    809:   Add log in  imach.c and  fullversion number is now printed.
                    810: 
                    811: */
                    812: /*
                    813:    Interpolated Markov Chain
                    814: 
                    815:   Short summary of the programme:
                    816:   
1.227     brouard   817:   This program computes Healthy Life Expectancies or State-specific
                    818:   (if states aren't health statuses) Expectancies from
                    819:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    820: 
                    821:   -1- a first survey ("cross") where individuals from different ages
                    822:   are interviewed on their health status or degree of disability (in
                    823:   the case of a health survey which is our main interest)
                    824: 
                    825:   -2- at least a second wave of interviews ("longitudinal") which
                    826:   measure each change (if any) in individual health status.  Health
                    827:   expectancies are computed from the time spent in each health state
                    828:   according to a model. More health states you consider, more time is
                    829:   necessary to reach the Maximum Likelihood of the parameters involved
                    830:   in the model.  The simplest model is the multinomial logistic model
                    831:   where pij is the probability to be observed in state j at the second
                    832:   wave conditional to be observed in state i at the first
                    833:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    834:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    835:   have a more complex model than "constant and age", you should modify
                    836:   the program where the markup *Covariates have to be included here
                    837:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   838:   convergence.
                    839: 
                    840:   The advantage of this computer programme, compared to a simple
                    841:   multinomial logistic model, is clear when the delay between waves is not
                    842:   identical for each individual. Also, if a individual missed an
                    843:   intermediate interview, the information is lost, but taken into
                    844:   account using an interpolation or extrapolation.  
                    845: 
                    846:   hPijx is the probability to be observed in state i at age x+h
                    847:   conditional to the observed state i at age x. The delay 'h' can be
                    848:   split into an exact number (nh*stepm) of unobserved intermediate
                    849:   states. This elementary transition (by month, quarter,
                    850:   semester or year) is modelled as a multinomial logistic.  The hPx
                    851:   matrix is simply the matrix product of nh*stepm elementary matrices
                    852:   and the contribution of each individual to the likelihood is simply
                    853:   hPijx.
                    854: 
                    855:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   856:   of the life expectancies. It also computes the period (stable) prevalence.
                    857: 
                    858: Back prevalence and projections:
1.227     brouard   859: 
                    860:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    861:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    862:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    863:    mobilavproj)
                    864: 
                    865:     Computes the back prevalence limit for any combination of
                    866:     covariate values k at any age between ageminpar and agemaxpar and
                    867:     returns it in **bprlim. In the loops,
                    868: 
                    869:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    870:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    871: 
                    872:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   873:    Computes for any combination of covariates k and any age between bage and fage 
                    874:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    875:                        oldm=oldms;savm=savms;
1.227     brouard   876: 
1.267     brouard   877:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   878:      Computes the transition matrix starting at age 'age' over
                    879:      'nhstepm*hstepm*stepm' months (i.e. until
                    880:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   881:      nhstepm*hstepm matrices. 
                    882: 
                    883:      Returns p3mat[i][j][h] after calling
                    884:      p3mat[i][j][h]=matprod2(newm,
                    885:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    886:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    887:      oldm);
1.226     brouard   888: 
                    889: Important routines
                    890: 
                    891: - func (or funcone), computes logit (pij) distinguishing
                    892:   o fixed variables (single or product dummies or quantitative);
                    893:   o varying variables by:
                    894:    (1) wave (single, product dummies, quantitative), 
                    895:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    896:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    897:        % varying dummy (not done) or quantitative (not done);
                    898: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    899:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    900: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    901:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    902:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   903: 
1.226     brouard   904: 
                    905:   
1.133     brouard   906:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    907:            Institut national d'études démographiques, Paris.
1.126     brouard   908:   This software have been partly granted by Euro-REVES, a concerted action
                    909:   from the European Union.
                    910:   It is copyrighted identically to a GNU software product, ie programme and
                    911:   software can be distributed freely for non commercial use. Latest version
                    912:   can be accessed at http://euroreves.ined.fr/imach .
                    913: 
                    914:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    915:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    916:   
                    917:   **********************************************************************/
                    918: /*
                    919:   main
                    920:   read parameterfile
                    921:   read datafile
                    922:   concatwav
                    923:   freqsummary
                    924:   if (mle >= 1)
                    925:     mlikeli
                    926:   print results files
                    927:   if mle==1 
                    928:      computes hessian
                    929:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    930:       begin-prev-date,...
                    931:   open gnuplot file
                    932:   open html file
1.145     brouard   933:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    934:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    935:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    936:     freexexit2 possible for memory heap.
                    937: 
                    938:   h Pij x                         | pij_nom  ficrestpij
                    939:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    940:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    941:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    942: 
                    943:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    944:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    945:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    946:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    947:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    948: 
1.126     brouard   949:   forecasting if prevfcast==1 prevforecast call prevalence()
                    950:   health expectancies
                    951:   Variance-covariance of DFLE
                    952:   prevalence()
                    953:    movingaverage()
                    954:   varevsij() 
                    955:   if popbased==1 varevsij(,popbased)
                    956:   total life expectancies
                    957:   Variance of period (stable) prevalence
                    958:  end
                    959: */
                    960: 
1.187     brouard   961: /* #define DEBUG */
                    962: /* #define DEBUGBRENT */
1.203     brouard   963: /* #define DEBUGLINMIN */
                    964: /* #define DEBUGHESS */
                    965: #define DEBUGHESSIJ
1.224     brouard   966: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   967: #define POWELL /* Instead of NLOPT */
1.224     brouard   968: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   969: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    970: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   971: 
                    972: #include <math.h>
                    973: #include <stdio.h>
                    974: #include <stdlib.h>
                    975: #include <string.h>
1.226     brouard   976: #include <ctype.h>
1.159     brouard   977: 
                    978: #ifdef _WIN32
                    979: #include <io.h>
1.172     brouard   980: #include <windows.h>
                    981: #include <tchar.h>
1.159     brouard   982: #else
1.126     brouard   983: #include <unistd.h>
1.159     brouard   984: #endif
1.126     brouard   985: 
                    986: #include <limits.h>
                    987: #include <sys/types.h>
1.171     brouard   988: 
                    989: #if defined(__GNUC__)
                    990: #include <sys/utsname.h> /* Doesn't work on Windows */
                    991: #endif
                    992: 
1.126     brouard   993: #include <sys/stat.h>
                    994: #include <errno.h>
1.159     brouard   995: /* extern int errno; */
1.126     brouard   996: 
1.157     brouard   997: /* #ifdef LINUX */
                    998: /* #include <time.h> */
                    999: /* #include "timeval.h" */
                   1000: /* #else */
                   1001: /* #include <sys/time.h> */
                   1002: /* #endif */
                   1003: 
1.126     brouard  1004: #include <time.h>
                   1005: 
1.136     brouard  1006: #ifdef GSL
                   1007: #include <gsl/gsl_errno.h>
                   1008: #include <gsl/gsl_multimin.h>
                   1009: #endif
                   1010: 
1.167     brouard  1011: 
1.162     brouard  1012: #ifdef NLOPT
                   1013: #include <nlopt.h>
                   1014: typedef struct {
                   1015:   double (* function)(double [] );
                   1016: } myfunc_data ;
                   1017: #endif
                   1018: 
1.126     brouard  1019: /* #include <libintl.h> */
                   1020: /* #define _(String) gettext (String) */
                   1021: 
1.251     brouard  1022: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1023: 
                   1024: #define GNUPLOTPROGRAM "gnuplot"
                   1025: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1026: #define FILENAMELENGTH 132
                   1027: 
                   1028: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1029: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1030: 
1.144     brouard  1031: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1032: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1033: 
                   1034: #define NINTERVMAX 8
1.144     brouard  1035: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1036: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1037: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1038: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1039: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1040: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1041: #define MAXN 20000
1.144     brouard  1042: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1043: /* #define AGESUP 130 */
                   1044: #define AGESUP 150
1.268     brouard  1045: #define AGEINF 0
1.218     brouard  1046: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1047: #define AGEBASE 40
1.194     brouard  1048: #define AGEOVERFLOW 1.e20
1.164     brouard  1049: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1050: #ifdef _WIN32
                   1051: #define DIRSEPARATOR '\\'
                   1052: #define CHARSEPARATOR "\\"
                   1053: #define ODIRSEPARATOR '/'
                   1054: #else
1.126     brouard  1055: #define DIRSEPARATOR '/'
                   1056: #define CHARSEPARATOR "/"
                   1057: #define ODIRSEPARATOR '\\'
                   1058: #endif
                   1059: 
1.285   ! brouard  1060: /* $Id: imach.c,v 1.284 2018/04/20 05:22:13 brouard Exp $ */
1.126     brouard  1061: /* $State: Exp $ */
1.196     brouard  1062: #include "version.h"
                   1063: char version[]=__IMACH_VERSION__;
1.283     brouard  1064: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.285   ! brouard  1065: char fullversion[]="$Revision: 1.284 $ $Date: 2018/04/20 05:22:13 $"; 
1.126     brouard  1066: char strstart[80];
                   1067: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1068: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1069: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1070: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1071: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1072: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1073: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1074: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1075: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1076: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1077: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1078: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1079: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1080: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1081: int nsd=0; /**< Total number of single dummy variables (output) */
                   1082: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1083: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1084: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1085: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1086: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1087: int cptcov=0; /* Working variable */
1.218     brouard  1088: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1089: int npar=NPARMAX;
                   1090: int nlstate=2; /* Number of live states */
                   1091: int ndeath=1; /* Number of dead states */
1.130     brouard  1092: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1093: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1094: int popbased=0;
                   1095: 
                   1096: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1097: int maxwav=0; /* Maxim number of waves */
                   1098: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1099: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1100: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1101:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1102: int mle=1, weightopt=0;
1.126     brouard  1103: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1104: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1105: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1106:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1107: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1108: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1109: 
1.130     brouard  1110: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1111: double **matprod2(); /* test */
1.126     brouard  1112: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1113: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1114: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1115: 
1.136     brouard  1116: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1117: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1118: FILE *ficlog, *ficrespow;
1.130     brouard  1119: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1120: double fretone; /* Only one call to likelihood */
1.130     brouard  1121: long ipmx=0; /* Number of contributions */
1.126     brouard  1122: double sw; /* Sum of weights */
                   1123: char filerespow[FILENAMELENGTH];
                   1124: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1125: FILE *ficresilk;
                   1126: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1127: FILE *ficresprobmorprev;
                   1128: FILE *fichtm, *fichtmcov; /* Html File */
                   1129: FILE *ficreseij;
                   1130: char filerese[FILENAMELENGTH];
                   1131: FILE *ficresstdeij;
                   1132: char fileresstde[FILENAMELENGTH];
                   1133: FILE *ficrescveij;
                   1134: char filerescve[FILENAMELENGTH];
                   1135: FILE  *ficresvij;
                   1136: char fileresv[FILENAMELENGTH];
1.269     brouard  1137: 
1.126     brouard  1138: char title[MAXLINE];
1.234     brouard  1139: char model[MAXLINE]; /**< The model line */
1.217     brouard  1140: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1141: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1142: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1143: char command[FILENAMELENGTH];
                   1144: int  outcmd=0;
                   1145: 
1.217     brouard  1146: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1147: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1148: char filelog[FILENAMELENGTH]; /* Log file */
                   1149: char filerest[FILENAMELENGTH];
                   1150: char fileregp[FILENAMELENGTH];
                   1151: char popfile[FILENAMELENGTH];
                   1152: 
                   1153: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1154: 
1.157     brouard  1155: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1156: /* struct timezone tzp; */
                   1157: /* extern int gettimeofday(); */
                   1158: struct tm tml, *gmtime(), *localtime();
                   1159: 
                   1160: extern time_t time();
                   1161: 
                   1162: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1163: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1164: struct tm tm;
                   1165: 
1.126     brouard  1166: char strcurr[80], strfor[80];
                   1167: 
                   1168: char *endptr;
                   1169: long lval;
                   1170: double dval;
                   1171: 
                   1172: #define NR_END 1
                   1173: #define FREE_ARG char*
                   1174: #define FTOL 1.0e-10
                   1175: 
                   1176: #define NRANSI 
1.240     brouard  1177: #define ITMAX 200
                   1178: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1179: 
                   1180: #define TOL 2.0e-4 
                   1181: 
                   1182: #define CGOLD 0.3819660 
                   1183: #define ZEPS 1.0e-10 
                   1184: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1185: 
                   1186: #define GOLD 1.618034 
                   1187: #define GLIMIT 100.0 
                   1188: #define TINY 1.0e-20 
                   1189: 
                   1190: static double maxarg1,maxarg2;
                   1191: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1192: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1193:   
                   1194: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1195: #define rint(a) floor(a+0.5)
1.166     brouard  1196: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1197: #define mytinydouble 1.0e-16
1.166     brouard  1198: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1199: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1200: /* static double dsqrarg; */
                   1201: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1202: static double sqrarg;
                   1203: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1204: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1205: int agegomp= AGEGOMP;
                   1206: 
                   1207: int imx; 
                   1208: int stepm=1;
                   1209: /* Stepm, step in month: minimum step interpolation*/
                   1210: 
                   1211: int estepm;
                   1212: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1213: 
                   1214: int m,nb;
                   1215: long *num;
1.197     brouard  1216: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1217: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1218:                   covariate for which somebody answered excluding 
                   1219:                   undefined. Usually 2: 0 and 1. */
                   1220: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1221:                             covariate for which somebody answered including 
                   1222:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1223: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1224: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1225: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1226: double *ageexmed,*agecens;
                   1227: double dateintmean=0;
                   1228: 
                   1229: double *weight;
                   1230: int **s; /* Status */
1.141     brouard  1231: double *agedc;
1.145     brouard  1232: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1233:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1234:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1235: double **coqvar; /* Fixed quantitative covariate nqv */
                   1236: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1237: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1238: double  idx; 
                   1239: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1240: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1241: /*k          1  2   3   4     5    6    7     8    9 */
                   1242: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1243: /* Tndvar[k]    1   2   3               4          5 */
                   1244: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1245: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1246: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1247: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1248: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1249: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1250: /* Tprod[i]=k           4               7            */
                   1251: /* Tage[i]=k                  5               8      */
                   1252: /* */
                   1253: /* Type                    */
                   1254: /* V         1  2  3  4  5 */
                   1255: /*           F  F  V  V  V */
                   1256: /*           D  Q  D  D  Q */
                   1257: /*                         */
                   1258: int *TvarsD;
                   1259: int *TvarsDind;
                   1260: int *TvarsQ;
                   1261: int *TvarsQind;
                   1262: 
1.235     brouard  1263: #define MAXRESULTLINES 10
                   1264: int nresult=0;
1.258     brouard  1265: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1266: int TKresult[MAXRESULTLINES];
1.237     brouard  1267: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1268: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1269: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1270: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1271: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1272: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1273: 
1.234     brouard  1274: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1275: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1276: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1277: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1278: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1279: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1280: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1281: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1282: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1283: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1284: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1285: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1286: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1287: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1288: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1289: 
1.230     brouard  1290: int *Tvarsel; /**< Selected covariates for output */
                   1291: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1292: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1293: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1294: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1295: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1296: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1297: int *Tage;
1.227     brouard  1298: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1299: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1300: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1301: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1302: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1303: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1304: int **Tvard;
                   1305: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1306: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1307: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1308:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1309:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1310: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1311: double *lsurv, *lpop, *tpop;
                   1312: 
1.231     brouard  1313: #define FD 1; /* Fixed dummy covariate */
                   1314: #define FQ 2; /* Fixed quantitative covariate */
                   1315: #define FP 3; /* Fixed product covariate */
                   1316: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1317: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1318: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1319: #define VD 10; /* Varying dummy covariate */
                   1320: #define VQ 11; /* Varying quantitative covariate */
                   1321: #define VP 12; /* Varying product covariate */
                   1322: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1323: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1324: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1325: #define APFD 16; /* Age product * fixed dummy covariate */
                   1326: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1327: #define APVD 18; /* Age product * varying dummy covariate */
                   1328: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1329: 
                   1330: #define FTYPE 1; /* Fixed covariate */
                   1331: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1332: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1333: 
                   1334: struct kmodel{
                   1335:        int maintype; /* main type */
                   1336:        int subtype; /* subtype */
                   1337: };
                   1338: struct kmodel modell[NCOVMAX];
                   1339: 
1.143     brouard  1340: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1341: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1342: 
                   1343: /**************** split *************************/
                   1344: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1345: {
                   1346:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1347:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1348:   */ 
                   1349:   char *ss;                            /* pointer */
1.186     brouard  1350:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1351: 
                   1352:   l1 = strlen(path );                  /* length of path */
                   1353:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1354:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1355:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1356:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1357:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1358:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1359:     /* get current working directory */
                   1360:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1361: #ifdef WIN32
                   1362:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1363: #else
                   1364:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1365: #endif
1.126     brouard  1366:       return( GLOCK_ERROR_GETCWD );
                   1367:     }
                   1368:     /* got dirc from getcwd*/
                   1369:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1370:   } else {                             /* strip directory from path */
1.126     brouard  1371:     ss++;                              /* after this, the filename */
                   1372:     l2 = strlen( ss );                 /* length of filename */
                   1373:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1374:     strcpy( name, ss );                /* save file name */
                   1375:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1376:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1377:     printf(" DIRC2 = %s \n",dirc);
                   1378:   }
                   1379:   /* We add a separator at the end of dirc if not exists */
                   1380:   l1 = strlen( dirc );                 /* length of directory */
                   1381:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1382:     dirc[l1] =  DIRSEPARATOR;
                   1383:     dirc[l1+1] = 0; 
                   1384:     printf(" DIRC3 = %s \n",dirc);
                   1385:   }
                   1386:   ss = strrchr( name, '.' );           /* find last / */
                   1387:   if (ss >0){
                   1388:     ss++;
                   1389:     strcpy(ext,ss);                    /* save extension */
                   1390:     l1= strlen( name);
                   1391:     l2= strlen(ss)+1;
                   1392:     strncpy( finame, name, l1-l2);
                   1393:     finame[l1-l2]= 0;
                   1394:   }
                   1395: 
                   1396:   return( 0 );                         /* we're done */
                   1397: }
                   1398: 
                   1399: 
                   1400: /******************************************/
                   1401: 
                   1402: void replace_back_to_slash(char *s, char*t)
                   1403: {
                   1404:   int i;
                   1405:   int lg=0;
                   1406:   i=0;
                   1407:   lg=strlen(t);
                   1408:   for(i=0; i<= lg; i++) {
                   1409:     (s[i] = t[i]);
                   1410:     if (t[i]== '\\') s[i]='/';
                   1411:   }
                   1412: }
                   1413: 
1.132     brouard  1414: char *trimbb(char *out, char *in)
1.137     brouard  1415: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1416:   char *s;
                   1417:   s=out;
                   1418:   while (*in != '\0'){
1.137     brouard  1419:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1420:       in++;
                   1421:     }
                   1422:     *out++ = *in++;
                   1423:   }
                   1424:   *out='\0';
                   1425:   return s;
                   1426: }
                   1427: 
1.187     brouard  1428: /* char *substrchaine(char *out, char *in, char *chain) */
                   1429: /* { */
                   1430: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1431: /*   char *s, *t; */
                   1432: /*   t=in;s=out; */
                   1433: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1434: /*     *out++ = *in++; */
                   1435: /*   } */
                   1436: 
                   1437: /*   /\* *in matches *chain *\/ */
                   1438: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1439: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1440: /*   } */
                   1441: /*   in--; chain--; */
                   1442: /*   while ( (*in != '\0')){ */
                   1443: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1444: /*     *out++ = *in++; */
                   1445: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1446: /*   } */
                   1447: /*   *out='\0'; */
                   1448: /*   out=s; */
                   1449: /*   return out; */
                   1450: /* } */
                   1451: char *substrchaine(char *out, char *in, char *chain)
                   1452: {
                   1453:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1454:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1455: 
                   1456:   char *strloc;
                   1457: 
                   1458:   strcpy (out, in); 
                   1459:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1460:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1461:   if(strloc != NULL){ 
                   1462:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1463:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1464:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1465:   }
                   1466:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1467:   return out;
                   1468: }
                   1469: 
                   1470: 
1.145     brouard  1471: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1472: {
1.187     brouard  1473:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1474:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1475:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1476:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1477:   */
1.160     brouard  1478:   char *s, *t;
1.145     brouard  1479:   t=in;s=in;
                   1480:   while ((*in != occ) && (*in != '\0')){
                   1481:     *alocc++ = *in++;
                   1482:   }
                   1483:   if( *in == occ){
                   1484:     *(alocc)='\0';
                   1485:     s=++in;
                   1486:   }
                   1487:  
                   1488:   if (s == t) {/* occ not found */
                   1489:     *(alocc-(in-s))='\0';
                   1490:     in=s;
                   1491:   }
                   1492:   while ( *in != '\0'){
                   1493:     *blocc++ = *in++;
                   1494:   }
                   1495: 
                   1496:   *blocc='\0';
                   1497:   return t;
                   1498: }
1.137     brouard  1499: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1500: {
1.187     brouard  1501:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1502:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1503:      gives blocc="abcdef2ghi" and alocc="j".
                   1504:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1505:   */
                   1506:   char *s, *t;
                   1507:   t=in;s=in;
                   1508:   while (*in != '\0'){
                   1509:     while( *in == occ){
                   1510:       *blocc++ = *in++;
                   1511:       s=in;
                   1512:     }
                   1513:     *blocc++ = *in++;
                   1514:   }
                   1515:   if (s == t) /* occ not found */
                   1516:     *(blocc-(in-s))='\0';
                   1517:   else
                   1518:     *(blocc-(in-s)-1)='\0';
                   1519:   in=s;
                   1520:   while ( *in != '\0'){
                   1521:     *alocc++ = *in++;
                   1522:   }
                   1523: 
                   1524:   *alocc='\0';
                   1525:   return s;
                   1526: }
                   1527: 
1.126     brouard  1528: int nbocc(char *s, char occ)
                   1529: {
                   1530:   int i,j=0;
                   1531:   int lg=20;
                   1532:   i=0;
                   1533:   lg=strlen(s);
                   1534:   for(i=0; i<= lg; i++) {
1.234     brouard  1535:     if  (s[i] == occ ) j++;
1.126     brouard  1536:   }
                   1537:   return j;
                   1538: }
                   1539: 
1.137     brouard  1540: /* void cutv(char *u,char *v, char*t, char occ) */
                   1541: /* { */
                   1542: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1543: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1544: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1545: /*   int i,lg,j,p=0; */
                   1546: /*   i=0; */
                   1547: /*   lg=strlen(t); */
                   1548: /*   for(j=0; j<=lg-1; j++) { */
                   1549: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1550: /*   } */
1.126     brouard  1551: 
1.137     brouard  1552: /*   for(j=0; j<p; j++) { */
                   1553: /*     (u[j] = t[j]); */
                   1554: /*   } */
                   1555: /*      u[p]='\0'; */
1.126     brouard  1556: 
1.137     brouard  1557: /*    for(j=0; j<= lg; j++) { */
                   1558: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1559: /*   } */
                   1560: /* } */
1.126     brouard  1561: 
1.160     brouard  1562: #ifdef _WIN32
                   1563: char * strsep(char **pp, const char *delim)
                   1564: {
                   1565:   char *p, *q;
                   1566:          
                   1567:   if ((p = *pp) == NULL)
                   1568:     return 0;
                   1569:   if ((q = strpbrk (p, delim)) != NULL)
                   1570:   {
                   1571:     *pp = q + 1;
                   1572:     *q = '\0';
                   1573:   }
                   1574:   else
                   1575:     *pp = 0;
                   1576:   return p;
                   1577: }
                   1578: #endif
                   1579: 
1.126     brouard  1580: /********************** nrerror ********************/
                   1581: 
                   1582: void nrerror(char error_text[])
                   1583: {
                   1584:   fprintf(stderr,"ERREUR ...\n");
                   1585:   fprintf(stderr,"%s\n",error_text);
                   1586:   exit(EXIT_FAILURE);
                   1587: }
                   1588: /*********************** vector *******************/
                   1589: double *vector(int nl, int nh)
                   1590: {
                   1591:   double *v;
                   1592:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1593:   if (!v) nrerror("allocation failure in vector");
                   1594:   return v-nl+NR_END;
                   1595: }
                   1596: 
                   1597: /************************ free vector ******************/
                   1598: void free_vector(double*v, int nl, int nh)
                   1599: {
                   1600:   free((FREE_ARG)(v+nl-NR_END));
                   1601: }
                   1602: 
                   1603: /************************ivector *******************************/
                   1604: int *ivector(long nl,long nh)
                   1605: {
                   1606:   int *v;
                   1607:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1608:   if (!v) nrerror("allocation failure in ivector");
                   1609:   return v-nl+NR_END;
                   1610: }
                   1611: 
                   1612: /******************free ivector **************************/
                   1613: void free_ivector(int *v, long nl, long nh)
                   1614: {
                   1615:   free((FREE_ARG)(v+nl-NR_END));
                   1616: }
                   1617: 
                   1618: /************************lvector *******************************/
                   1619: long *lvector(long nl,long nh)
                   1620: {
                   1621:   long *v;
                   1622:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1623:   if (!v) nrerror("allocation failure in ivector");
                   1624:   return v-nl+NR_END;
                   1625: }
                   1626: 
                   1627: /******************free lvector **************************/
                   1628: void free_lvector(long *v, long nl, long nh)
                   1629: {
                   1630:   free((FREE_ARG)(v+nl-NR_END));
                   1631: }
                   1632: 
                   1633: /******************* imatrix *******************************/
                   1634: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1635:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1636: { 
                   1637:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1638:   int **m; 
                   1639:   
                   1640:   /* allocate pointers to rows */ 
                   1641:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1642:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1643:   m += NR_END; 
                   1644:   m -= nrl; 
                   1645:   
                   1646:   
                   1647:   /* allocate rows and set pointers to them */ 
                   1648:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1649:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1650:   m[nrl] += NR_END; 
                   1651:   m[nrl] -= ncl; 
                   1652:   
                   1653:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1654:   
                   1655:   /* return pointer to array of pointers to rows */ 
                   1656:   return m; 
                   1657: } 
                   1658: 
                   1659: /****************** free_imatrix *************************/
                   1660: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1661:       int **m;
                   1662:       long nch,ncl,nrh,nrl; 
                   1663:      /* free an int matrix allocated by imatrix() */ 
                   1664: { 
                   1665:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1666:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1667: } 
                   1668: 
                   1669: /******************* matrix *******************************/
                   1670: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1671: {
                   1672:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1673:   double **m;
                   1674: 
                   1675:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1676:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1677:   m += NR_END;
                   1678:   m -= nrl;
                   1679: 
                   1680:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1681:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1682:   m[nrl] += NR_END;
                   1683:   m[nrl] -= ncl;
                   1684: 
                   1685:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1686:   return m;
1.145     brouard  1687:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1688: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1689: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1690:    */
                   1691: }
                   1692: 
                   1693: /*************************free matrix ************************/
                   1694: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1695: {
                   1696:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1697:   free((FREE_ARG)(m+nrl-NR_END));
                   1698: }
                   1699: 
                   1700: /******************* ma3x *******************************/
                   1701: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1702: {
                   1703:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1704:   double ***m;
                   1705: 
                   1706:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1707:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1708:   m += NR_END;
                   1709:   m -= nrl;
                   1710: 
                   1711:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1712:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1713:   m[nrl] += NR_END;
                   1714:   m[nrl] -= ncl;
                   1715: 
                   1716:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1717: 
                   1718:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1719:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1720:   m[nrl][ncl] += NR_END;
                   1721:   m[nrl][ncl] -= nll;
                   1722:   for (j=ncl+1; j<=nch; j++) 
                   1723:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1724:   
                   1725:   for (i=nrl+1; i<=nrh; i++) {
                   1726:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1727:     for (j=ncl+1; j<=nch; j++) 
                   1728:       m[i][j]=m[i][j-1]+nlay;
                   1729:   }
                   1730:   return m; 
                   1731:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1732:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1733:   */
                   1734: }
                   1735: 
                   1736: /*************************free ma3x ************************/
                   1737: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1738: {
                   1739:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1740:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1741:   free((FREE_ARG)(m+nrl-NR_END));
                   1742: }
                   1743: 
                   1744: /*************** function subdirf ***********/
                   1745: char *subdirf(char fileres[])
                   1746: {
                   1747:   /* Caution optionfilefiname is hidden */
                   1748:   strcpy(tmpout,optionfilefiname);
                   1749:   strcat(tmpout,"/"); /* Add to the right */
                   1750:   strcat(tmpout,fileres);
                   1751:   return tmpout;
                   1752: }
                   1753: 
                   1754: /*************** function subdirf2 ***********/
                   1755: char *subdirf2(char fileres[], char *preop)
                   1756: {
                   1757:   
                   1758:   /* Caution optionfilefiname is hidden */
                   1759:   strcpy(tmpout,optionfilefiname);
                   1760:   strcat(tmpout,"/");
                   1761:   strcat(tmpout,preop);
                   1762:   strcat(tmpout,fileres);
                   1763:   return tmpout;
                   1764: }
                   1765: 
                   1766: /*************** function subdirf3 ***********/
                   1767: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1768: {
                   1769:   
                   1770:   /* Caution optionfilefiname is hidden */
                   1771:   strcpy(tmpout,optionfilefiname);
                   1772:   strcat(tmpout,"/");
                   1773:   strcat(tmpout,preop);
                   1774:   strcat(tmpout,preop2);
                   1775:   strcat(tmpout,fileres);
                   1776:   return tmpout;
                   1777: }
1.213     brouard  1778:  
                   1779: /*************** function subdirfext ***********/
                   1780: char *subdirfext(char fileres[], char *preop, char *postop)
                   1781: {
                   1782:   
                   1783:   strcpy(tmpout,preop);
                   1784:   strcat(tmpout,fileres);
                   1785:   strcat(tmpout,postop);
                   1786:   return tmpout;
                   1787: }
1.126     brouard  1788: 
1.213     brouard  1789: /*************** function subdirfext3 ***********/
                   1790: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1791: {
                   1792:   
                   1793:   /* Caution optionfilefiname is hidden */
                   1794:   strcpy(tmpout,optionfilefiname);
                   1795:   strcat(tmpout,"/");
                   1796:   strcat(tmpout,preop);
                   1797:   strcat(tmpout,fileres);
                   1798:   strcat(tmpout,postop);
                   1799:   return tmpout;
                   1800: }
                   1801:  
1.162     brouard  1802: char *asc_diff_time(long time_sec, char ascdiff[])
                   1803: {
                   1804:   long sec_left, days, hours, minutes;
                   1805:   days = (time_sec) / (60*60*24);
                   1806:   sec_left = (time_sec) % (60*60*24);
                   1807:   hours = (sec_left) / (60*60) ;
                   1808:   sec_left = (sec_left) %(60*60);
                   1809:   minutes = (sec_left) /60;
                   1810:   sec_left = (sec_left) % (60);
                   1811:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1812:   return ascdiff;
                   1813: }
                   1814: 
1.126     brouard  1815: /***************** f1dim *************************/
                   1816: extern int ncom; 
                   1817: extern double *pcom,*xicom;
                   1818: extern double (*nrfunc)(double []); 
                   1819:  
                   1820: double f1dim(double x) 
                   1821: { 
                   1822:   int j; 
                   1823:   double f;
                   1824:   double *xt; 
                   1825:  
                   1826:   xt=vector(1,ncom); 
                   1827:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1828:   f=(*nrfunc)(xt); 
                   1829:   free_vector(xt,1,ncom); 
                   1830:   return f; 
                   1831: } 
                   1832: 
                   1833: /*****************brent *************************/
                   1834: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1835: {
                   1836:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1837:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1838:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1839:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1840:    * returned function value. 
                   1841:   */
1.126     brouard  1842:   int iter; 
                   1843:   double a,b,d,etemp;
1.159     brouard  1844:   double fu=0,fv,fw,fx;
1.164     brouard  1845:   double ftemp=0.;
1.126     brouard  1846:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1847:   double e=0.0; 
                   1848:  
                   1849:   a=(ax < cx ? ax : cx); 
                   1850:   b=(ax > cx ? ax : cx); 
                   1851:   x=w=v=bx; 
                   1852:   fw=fv=fx=(*f)(x); 
                   1853:   for (iter=1;iter<=ITMAX;iter++) { 
                   1854:     xm=0.5*(a+b); 
                   1855:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1856:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1857:     printf(".");fflush(stdout);
                   1858:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1859: #ifdef DEBUGBRENT
1.126     brouard  1860:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1861:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1862:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1863: #endif
                   1864:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1865:       *xmin=x; 
                   1866:       return fx; 
                   1867:     } 
                   1868:     ftemp=fu;
                   1869:     if (fabs(e) > tol1) { 
                   1870:       r=(x-w)*(fx-fv); 
                   1871:       q=(x-v)*(fx-fw); 
                   1872:       p=(x-v)*q-(x-w)*r; 
                   1873:       q=2.0*(q-r); 
                   1874:       if (q > 0.0) p = -p; 
                   1875:       q=fabs(q); 
                   1876:       etemp=e; 
                   1877:       e=d; 
                   1878:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1879:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1880:       else { 
1.224     brouard  1881:                                d=p/q; 
                   1882:                                u=x+d; 
                   1883:                                if (u-a < tol2 || b-u < tol2) 
                   1884:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1885:       } 
                   1886:     } else { 
                   1887:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1888:     } 
                   1889:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1890:     fu=(*f)(u); 
                   1891:     if (fu <= fx) { 
                   1892:       if (u >= x) a=x; else b=x; 
                   1893:       SHFT(v,w,x,u) 
1.183     brouard  1894:       SHFT(fv,fw,fx,fu) 
                   1895:     } else { 
                   1896:       if (u < x) a=u; else b=u; 
                   1897:       if (fu <= fw || w == x) { 
1.224     brouard  1898:                                v=w; 
                   1899:                                w=u; 
                   1900:                                fv=fw; 
                   1901:                                fw=fu; 
1.183     brouard  1902:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1903:                                v=u; 
                   1904:                                fv=fu; 
1.183     brouard  1905:       } 
                   1906:     } 
1.126     brouard  1907:   } 
                   1908:   nrerror("Too many iterations in brent"); 
                   1909:   *xmin=x; 
                   1910:   return fx; 
                   1911: } 
                   1912: 
                   1913: /****************** mnbrak ***********************/
                   1914: 
                   1915: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1916:            double (*func)(double)) 
1.183     brouard  1917: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1918: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1919: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1920: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1921:    */
1.126     brouard  1922:   double ulim,u,r,q, dum;
                   1923:   double fu; 
1.187     brouard  1924: 
                   1925:   double scale=10.;
                   1926:   int iterscale=0;
                   1927: 
                   1928:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1929:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1930: 
                   1931: 
                   1932:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1933:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1934:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1935:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1936:   /* } */
                   1937: 
1.126     brouard  1938:   if (*fb > *fa) { 
                   1939:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1940:     SHFT(dum,*fb,*fa,dum) 
                   1941:   } 
1.126     brouard  1942:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1943:   *fc=(*func)(*cx); 
1.183     brouard  1944: #ifdef DEBUG
1.224     brouard  1945:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1946:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1947: #endif
1.224     brouard  1948:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1949:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1950:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1951:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1952:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1953:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1954:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1955:       fu=(*func)(u); 
1.163     brouard  1956: #ifdef DEBUG
                   1957:       /* f(x)=A(x-u)**2+f(u) */
                   1958:       double A, fparabu; 
                   1959:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1960:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1961:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1962:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1963:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1964:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1965:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1966:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1967: #endif 
1.184     brouard  1968: #ifdef MNBRAKORIGINAL
1.183     brouard  1969: #else
1.191     brouard  1970: /*       if (fu > *fc) { */
                   1971: /* #ifdef DEBUG */
                   1972: /*       printf("mnbrak4  fu > fc \n"); */
                   1973: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1974: /* #endif */
                   1975: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1976: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1977: /*     dum=u; /\* Shifting c and u *\/ */
                   1978: /*     u = *cx; */
                   1979: /*     *cx = dum; */
                   1980: /*     dum = fu; */
                   1981: /*     fu = *fc; */
                   1982: /*     *fc =dum; */
                   1983: /*       } else { /\* end *\/ */
                   1984: /* #ifdef DEBUG */
                   1985: /*       printf("mnbrak3  fu < fc \n"); */
                   1986: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1987: /* #endif */
                   1988: /*     dum=u; /\* Shifting c and u *\/ */
                   1989: /*     u = *cx; */
                   1990: /*     *cx = dum; */
                   1991: /*     dum = fu; */
                   1992: /*     fu = *fc; */
                   1993: /*     *fc =dum; */
                   1994: /*       } */
1.224     brouard  1995: #ifdef DEBUGMNBRAK
                   1996:                 double A, fparabu; 
                   1997:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1998:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1999:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2000:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2001: #endif
1.191     brouard  2002:       dum=u; /* Shifting c and u */
                   2003:       u = *cx;
                   2004:       *cx = dum;
                   2005:       dum = fu;
                   2006:       fu = *fc;
                   2007:       *fc =dum;
1.183     brouard  2008: #endif
1.162     brouard  2009:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2010: #ifdef DEBUG
1.224     brouard  2011:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2012:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2013: #endif
1.126     brouard  2014:       fu=(*func)(u); 
                   2015:       if (fu < *fc) { 
1.183     brouard  2016: #ifdef DEBUG
1.224     brouard  2017:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2018:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2019: #endif
                   2020:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2021:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2022: #ifdef DEBUG
                   2023:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2024: #endif
                   2025:       } 
1.162     brouard  2026:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2027: #ifdef DEBUG
1.224     brouard  2028:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2029:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2030: #endif
1.126     brouard  2031:       u=ulim; 
                   2032:       fu=(*func)(u); 
1.183     brouard  2033:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2034: #ifdef DEBUG
1.224     brouard  2035:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2036:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2037: #endif
1.126     brouard  2038:       u=(*cx)+GOLD*(*cx-*bx); 
                   2039:       fu=(*func)(u); 
1.224     brouard  2040: #ifdef DEBUG
                   2041:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2042:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2043: #endif
1.183     brouard  2044:     } /* end tests */
1.126     brouard  2045:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2046:     SHFT(*fa,*fb,*fc,fu) 
                   2047: #ifdef DEBUG
1.224     brouard  2048:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2049:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2050: #endif
                   2051:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2052: } 
                   2053: 
                   2054: /*************** linmin ************************/
1.162     brouard  2055: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2056: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2057: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2058: the value of func at the returned location p . This is actually all accomplished by calling the
                   2059: routines mnbrak and brent .*/
1.126     brouard  2060: int ncom; 
                   2061: double *pcom,*xicom;
                   2062: double (*nrfunc)(double []); 
                   2063:  
1.224     brouard  2064: #ifdef LINMINORIGINAL
1.126     brouard  2065: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2066: #else
                   2067: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2068: #endif
1.126     brouard  2069: { 
                   2070:   double brent(double ax, double bx, double cx, 
                   2071:               double (*f)(double), double tol, double *xmin); 
                   2072:   double f1dim(double x); 
                   2073:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2074:              double *fc, double (*func)(double)); 
                   2075:   int j; 
                   2076:   double xx,xmin,bx,ax; 
                   2077:   double fx,fb,fa;
1.187     brouard  2078: 
1.203     brouard  2079: #ifdef LINMINORIGINAL
                   2080: #else
                   2081:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2082: #endif
                   2083:   
1.126     brouard  2084:   ncom=n; 
                   2085:   pcom=vector(1,n); 
                   2086:   xicom=vector(1,n); 
                   2087:   nrfunc=func; 
                   2088:   for (j=1;j<=n;j++) { 
                   2089:     pcom[j]=p[j]; 
1.202     brouard  2090:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2091:   } 
1.187     brouard  2092: 
1.203     brouard  2093: #ifdef LINMINORIGINAL
                   2094:   xx=1.;
                   2095: #else
                   2096:   axs=0.0;
                   2097:   xxs=1.;
                   2098:   do{
                   2099:     xx= xxs;
                   2100: #endif
1.187     brouard  2101:     ax=0.;
                   2102:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2103:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2104:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2105:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2106:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2107:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2108:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2109: #ifdef LINMINORIGINAL
                   2110: #else
                   2111:     if (fx != fx){
1.224     brouard  2112:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2113:                        printf("|");
                   2114:                        fprintf(ficlog,"|");
1.203     brouard  2115: #ifdef DEBUGLINMIN
1.224     brouard  2116:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2117: #endif
                   2118:     }
1.224     brouard  2119:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2120: #endif
                   2121:   
1.191     brouard  2122: #ifdef DEBUGLINMIN
                   2123:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2124:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2125: #endif
1.224     brouard  2126: #ifdef LINMINORIGINAL
                   2127: #else
                   2128:        if(fb == fx){ /* Flat function in the direction */
                   2129:                xmin=xx;
                   2130:     *flat=1;
                   2131:        }else{
                   2132:     *flat=0;
                   2133: #endif
                   2134:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2135:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2136:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2137:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2138:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2139:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2140: #ifdef DEBUG
1.224     brouard  2141:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2142:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2143: #endif
                   2144: #ifdef LINMINORIGINAL
                   2145: #else
                   2146:                        }
1.126     brouard  2147: #endif
1.191     brouard  2148: #ifdef DEBUGLINMIN
                   2149:   printf("linmin end ");
1.202     brouard  2150:   fprintf(ficlog,"linmin end ");
1.191     brouard  2151: #endif
1.126     brouard  2152:   for (j=1;j<=n;j++) { 
1.203     brouard  2153: #ifdef LINMINORIGINAL
                   2154:     xi[j] *= xmin; 
                   2155: #else
                   2156: #ifdef DEBUGLINMIN
                   2157:     if(xxs <1.0)
                   2158:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2159: #endif
                   2160:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2161: #ifdef DEBUGLINMIN
                   2162:     if(xxs <1.0)
                   2163:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2164: #endif
                   2165: #endif
1.187     brouard  2166:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2167:   } 
1.191     brouard  2168: #ifdef DEBUGLINMIN
1.203     brouard  2169:   printf("\n");
1.191     brouard  2170:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2171:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2172:   for (j=1;j<=n;j++) { 
1.202     brouard  2173:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2174:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2175:     if(j % ncovmodel == 0){
1.191     brouard  2176:       printf("\n");
1.202     brouard  2177:       fprintf(ficlog,"\n");
                   2178:     }
1.191     brouard  2179:   }
1.203     brouard  2180: #else
1.191     brouard  2181: #endif
1.126     brouard  2182:   free_vector(xicom,1,n); 
                   2183:   free_vector(pcom,1,n); 
                   2184: } 
                   2185: 
                   2186: 
                   2187: /*************** powell ************************/
1.162     brouard  2188: /*
                   2189: Minimization of a function func of n variables. Input consists of an initial starting point
                   2190: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2191: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2192: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2193: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2194: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2195:  */
1.224     brouard  2196: #ifdef LINMINORIGINAL
                   2197: #else
                   2198:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2199:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2200: #endif
1.126     brouard  2201: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2202:            double (*func)(double [])) 
                   2203: { 
1.224     brouard  2204: #ifdef LINMINORIGINAL
                   2205:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2206:              double (*func)(double [])); 
1.224     brouard  2207: #else 
1.241     brouard  2208:  void linmin(double p[], double xi[], int n, double *fret,
                   2209:             double (*func)(double []),int *flat); 
1.224     brouard  2210: #endif
1.239     brouard  2211:  int i,ibig,j,jk,k; 
1.126     brouard  2212:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2213:   double directest;
1.126     brouard  2214:   double fp,fptt;
                   2215:   double *xits;
                   2216:   int niterf, itmp;
1.224     brouard  2217: #ifdef LINMINORIGINAL
                   2218: #else
                   2219: 
                   2220:   flatdir=ivector(1,n); 
                   2221:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2222: #endif
1.126     brouard  2223: 
                   2224:   pt=vector(1,n); 
                   2225:   ptt=vector(1,n); 
                   2226:   xit=vector(1,n); 
                   2227:   xits=vector(1,n); 
                   2228:   *fret=(*func)(p); 
                   2229:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2230:   rcurr_time = time(NULL);  
1.126     brouard  2231:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2232:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2233:     ibig=0; 
                   2234:     del=0.0; 
1.157     brouard  2235:     rlast_time=rcurr_time;
                   2236:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2237:     rcurr_time = time(NULL);  
                   2238:     curr_time = *localtime(&rcurr_time);
                   2239:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2240:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2241: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2242:     for (i=1;i<=n;i++) {
1.126     brouard  2243:       fprintf(ficrespow," %.12lf", p[i]);
                   2244:     }
1.239     brouard  2245:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2246:     printf("\n#model=  1      +     age ");
                   2247:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2248:     if(nagesqr==1){
1.241     brouard  2249:        printf("  + age*age  ");
                   2250:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2251:     }
                   2252:     for(j=1;j <=ncovmodel-2;j++){
                   2253:       if(Typevar[j]==0) {
                   2254:        printf("  +      V%d  ",Tvar[j]);
                   2255:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2256:       }else if(Typevar[j]==1) {
                   2257:        printf("  +    V%d*age ",Tvar[j]);
                   2258:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2259:       }else if(Typevar[j]==2) {
                   2260:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2261:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2262:       }
                   2263:     }
1.126     brouard  2264:     printf("\n");
1.239     brouard  2265: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2266: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2267:     fprintf(ficlog,"\n");
1.239     brouard  2268:     for(i=1,jk=1; i <=nlstate; i++){
                   2269:       for(k=1; k <=(nlstate+ndeath); k++){
                   2270:        if (k != i) {
                   2271:          printf("%d%d ",i,k);
                   2272:          fprintf(ficlog,"%d%d ",i,k);
                   2273:          for(j=1; j <=ncovmodel; j++){
                   2274:            printf("%12.7f ",p[jk]);
                   2275:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2276:            jk++; 
                   2277:          }
                   2278:          printf("\n");
                   2279:          fprintf(ficlog,"\n");
                   2280:        }
                   2281:       }
                   2282:     }
1.241     brouard  2283:     if(*iter <=3 && *iter >1){
1.157     brouard  2284:       tml = *localtime(&rcurr_time);
                   2285:       strcpy(strcurr,asctime(&tml));
                   2286:       rforecast_time=rcurr_time; 
1.126     brouard  2287:       itmp = strlen(strcurr);
                   2288:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2289:        strcurr[itmp-1]='\0';
1.162     brouard  2290:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2291:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2292:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2293:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2294:        forecast_time = *localtime(&rforecast_time);
                   2295:        strcpy(strfor,asctime(&forecast_time));
                   2296:        itmp = strlen(strfor);
                   2297:        if(strfor[itmp-1]=='\n')
                   2298:          strfor[itmp-1]='\0';
                   2299:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2300:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2301:       }
                   2302:     }
1.187     brouard  2303:     for (i=1;i<=n;i++) { /* For each direction i */
                   2304:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2305:       fptt=(*fret); 
                   2306: #ifdef DEBUG
1.203     brouard  2307:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2308:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2309: #endif
1.203     brouard  2310:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2311:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2312: #ifdef LINMINORIGINAL
1.188     brouard  2313:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2314: #else
                   2315:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2316:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2317: #endif
                   2318:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2319:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2320:                                /* because that direction will be replaced unless the gain del is small */
                   2321:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2322:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2323:                                /* with the new direction. */
                   2324:                                del=fabs(fptt-(*fret)); 
                   2325:                                ibig=i; 
1.126     brouard  2326:       } 
                   2327: #ifdef DEBUG
                   2328:       printf("%d %.12e",i,(*fret));
                   2329:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2330:       for (j=1;j<=n;j++) {
1.224     brouard  2331:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2332:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2333:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2334:       }
                   2335:       for(j=1;j<=n;j++) {
1.225     brouard  2336:                                printf(" p(%d)=%.12e",j,p[j]);
                   2337:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2338:       }
                   2339:       printf("\n");
                   2340:       fprintf(ficlog,"\n");
                   2341: #endif
1.187     brouard  2342:     } /* end loop on each direction i */
                   2343:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2344:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2345:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2346:       for(j=1;j<=n;j++) {
1.225     brouard  2347:                                if(flatdir[j] >0){
                   2348:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2349:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2350:                                }
                   2351:                                /* printf("\n"); */
                   2352:                                /* fprintf(ficlog,"\n"); */
                   2353:                        }
1.243     brouard  2354:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2355:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2356:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2357:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2358:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2359:       /* decreased of more than 3.84  */
                   2360:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2361:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2362:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2363:                        
1.188     brouard  2364:       /* Starting the program with initial values given by a former maximization will simply change */
                   2365:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2366:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2367:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2368: #ifdef DEBUG
                   2369:       int k[2],l;
                   2370:       k[0]=1;
                   2371:       k[1]=-1;
                   2372:       printf("Max: %.12e",(*func)(p));
                   2373:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2374:       for (j=1;j<=n;j++) {
                   2375:        printf(" %.12e",p[j]);
                   2376:        fprintf(ficlog," %.12e",p[j]);
                   2377:       }
                   2378:       printf("\n");
                   2379:       fprintf(ficlog,"\n");
                   2380:       for(l=0;l<=1;l++) {
                   2381:        for (j=1;j<=n;j++) {
                   2382:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2383:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2384:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2385:        }
                   2386:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2387:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2388:       }
                   2389: #endif
                   2390: 
1.224     brouard  2391: #ifdef LINMINORIGINAL
                   2392: #else
                   2393:       free_ivector(flatdir,1,n); 
                   2394: #endif
1.126     brouard  2395:       free_vector(xit,1,n); 
                   2396:       free_vector(xits,1,n); 
                   2397:       free_vector(ptt,1,n); 
                   2398:       free_vector(pt,1,n); 
                   2399:       return; 
1.192     brouard  2400:     } /* enough precision */ 
1.240     brouard  2401:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2402:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2403:       ptt[j]=2.0*p[j]-pt[j]; 
                   2404:       xit[j]=p[j]-pt[j]; 
                   2405:       pt[j]=p[j]; 
                   2406:     } 
1.181     brouard  2407:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2408: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2409:                if (*iter <=4) {
1.225     brouard  2410: #else
                   2411: #endif
1.224     brouard  2412: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2413: #else
1.161     brouard  2414:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2415: #endif
1.162     brouard  2416:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2417:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2418:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2419:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2420:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2421:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2422:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2423:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2424:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2425:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2426:       /* mu² and del² are equal when f3=f1 */
                   2427:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2428:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2429:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2430:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2431: #ifdef NRCORIGINAL
                   2432:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2433: #else
                   2434:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2435:       t= t- del*SQR(fp-fptt);
1.183     brouard  2436: #endif
1.202     brouard  2437:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2438: #ifdef DEBUG
1.181     brouard  2439:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2440:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2441:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2442:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2443:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2444:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2445:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2446:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2447: #endif
1.183     brouard  2448: #ifdef POWELLORIGINAL
                   2449:       if (t < 0.0) { /* Then we use it for new direction */
                   2450: #else
1.182     brouard  2451:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2452:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2453:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2454:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2455:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2456:       } 
1.181     brouard  2457:       if (directest < 0.0) { /* Then we use it for new direction */
                   2458: #endif
1.191     brouard  2459: #ifdef DEBUGLINMIN
1.234     brouard  2460:        printf("Before linmin in direction P%d-P0\n",n);
                   2461:        for (j=1;j<=n;j++) {
                   2462:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2463:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2464:          if(j % ncovmodel == 0){
                   2465:            printf("\n");
                   2466:            fprintf(ficlog,"\n");
                   2467:          }
                   2468:        }
1.224     brouard  2469: #endif
                   2470: #ifdef LINMINORIGINAL
1.234     brouard  2471:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2472: #else
1.234     brouard  2473:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2474:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2475: #endif
1.234     brouard  2476:        
1.191     brouard  2477: #ifdef DEBUGLINMIN
1.234     brouard  2478:        for (j=1;j<=n;j++) { 
                   2479:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2480:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2481:          if(j % ncovmodel == 0){
                   2482:            printf("\n");
                   2483:            fprintf(ficlog,"\n");
                   2484:          }
                   2485:        }
1.224     brouard  2486: #endif
1.234     brouard  2487:        for (j=1;j<=n;j++) { 
                   2488:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2489:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2490:        }
1.224     brouard  2491: #ifdef LINMINORIGINAL
                   2492: #else
1.234     brouard  2493:        for (j=1, flatd=0;j<=n;j++) {
                   2494:          if(flatdir[j]>0)
                   2495:            flatd++;
                   2496:        }
                   2497:        if(flatd >0){
1.255     brouard  2498:          printf("%d flat directions: ",flatd);
                   2499:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2500:          for (j=1;j<=n;j++) { 
                   2501:            if(flatdir[j]>0){
                   2502:              printf("%d ",j);
                   2503:              fprintf(ficlog,"%d ",j);
                   2504:            }
                   2505:          }
                   2506:          printf("\n");
                   2507:          fprintf(ficlog,"\n");
                   2508:        }
1.191     brouard  2509: #endif
1.234     brouard  2510:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2511:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2512:        
1.126     brouard  2513: #ifdef DEBUG
1.234     brouard  2514:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2515:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2516:        for(j=1;j<=n;j++){
                   2517:          printf(" %lf",xit[j]);
                   2518:          fprintf(ficlog," %lf",xit[j]);
                   2519:        }
                   2520:        printf("\n");
                   2521:        fprintf(ficlog,"\n");
1.126     brouard  2522: #endif
1.192     brouard  2523:       } /* end of t or directest negative */
1.224     brouard  2524: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2525: #else
1.234     brouard  2526:       } /* end if (fptt < fp)  */
1.192     brouard  2527: #endif
1.225     brouard  2528: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2529:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2530: #else
1.224     brouard  2531: #endif
1.234     brouard  2532:                } /* loop iteration */ 
1.126     brouard  2533: } 
1.234     brouard  2534:   
1.126     brouard  2535: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2536:   
1.235     brouard  2537:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2538:   {
1.279     brouard  2539:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2540:      *   (and selected quantitative values in nres)
                   2541:      *  by left multiplying the unit
                   2542:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2543:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2544:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2545:      * or prevalence in state 1, prevalence in state 2, 0
                   2546:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2547:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2548:      * Output is prlim.
                   2549:      * Initial matrix pimij 
                   2550:      */
1.206     brouard  2551:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2552:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2553:   /*  0,                   0                  , 1} */
                   2554:   /*
                   2555:    * and after some iteration: */
                   2556:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2557:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2558:   /*  0,                   0                  , 1} */
                   2559:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2560:   /* {0.51571254859325999, 0.4842874514067399, */
                   2561:   /*  0.51326036147820708, 0.48673963852179264} */
                   2562:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2563:     
1.126     brouard  2564:   int i, ii,j,k;
1.209     brouard  2565:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2566:   /* double **matprod2(); */ /* test */
1.218     brouard  2567:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2568:   double **newm;
1.209     brouard  2569:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2570:   int ncvloop=0;
1.169     brouard  2571:   
1.209     brouard  2572:   min=vector(1,nlstate);
                   2573:   max=vector(1,nlstate);
                   2574:   meandiff=vector(1,nlstate);
                   2575: 
1.218     brouard  2576:        /* Starting with matrix unity */
1.126     brouard  2577:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2578:     for (j=1;j<=nlstate+ndeath;j++){
                   2579:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2580:     }
1.169     brouard  2581:   
                   2582:   cov[1]=1.;
                   2583:   
                   2584:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2585:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2586:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2587:     ncvloop++;
1.126     brouard  2588:     newm=savm;
                   2589:     /* Covariates have to be included here again */
1.138     brouard  2590:     cov[2]=agefin;
1.187     brouard  2591:     if(nagesqr==1)
                   2592:       cov[3]= agefin*agefin;;
1.234     brouard  2593:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2594:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2595:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2596:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2597:     }
                   2598:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2599:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2600:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2601:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2602:     }
1.237     brouard  2603:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2604:       if(Dummy[Tvar[Tage[k]]]){
                   2605:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2606:       } else{
1.235     brouard  2607:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2608:       }
1.235     brouard  2609:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2610:     }
1.237     brouard  2611:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2612:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2613:       if(Dummy[Tvard[k][1]==0]){
                   2614:        if(Dummy[Tvard[k][2]==0]){
                   2615:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2616:        }else{
                   2617:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2618:        }
                   2619:       }else{
                   2620:        if(Dummy[Tvard[k][2]==0]){
                   2621:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2622:        }else{
                   2623:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2624:        }
                   2625:       }
1.234     brouard  2626:     }
1.138     brouard  2627:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2628:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2629:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2630:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2631:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2632:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2633:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2634:     
1.126     brouard  2635:     savm=oldm;
                   2636:     oldm=newm;
1.209     brouard  2637: 
                   2638:     for(j=1; j<=nlstate; j++){
                   2639:       max[j]=0.;
                   2640:       min[j]=1.;
                   2641:     }
                   2642:     for(i=1;i<=nlstate;i++){
                   2643:       sumnew=0;
                   2644:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2645:       for(j=1; j<=nlstate; j++){ 
                   2646:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2647:        max[j]=FMAX(max[j],prlim[i][j]);
                   2648:        min[j]=FMIN(min[j],prlim[i][j]);
                   2649:       }
                   2650:     }
                   2651: 
1.126     brouard  2652:     maxmax=0.;
1.209     brouard  2653:     for(j=1; j<=nlstate; j++){
                   2654:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2655:       maxmax=FMAX(maxmax,meandiff[j]);
                   2656:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2657:     } /* j loop */
1.203     brouard  2658:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2659:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2660:     if(maxmax < ftolpl){
1.209     brouard  2661:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2662:       free_vector(min,1,nlstate);
                   2663:       free_vector(max,1,nlstate);
                   2664:       free_vector(meandiff,1,nlstate);
1.126     brouard  2665:       return prlim;
                   2666:     }
1.169     brouard  2667:   } /* age loop */
1.208     brouard  2668:     /* After some age loop it doesn't converge */
1.209     brouard  2669:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2670: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2671:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2672:   free_vector(min,1,nlstate);
                   2673:   free_vector(max,1,nlstate);
                   2674:   free_vector(meandiff,1,nlstate);
1.208     brouard  2675:   
1.169     brouard  2676:   return prlim; /* should not reach here */
1.126     brouard  2677: }
                   2678: 
1.217     brouard  2679: 
                   2680:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2681: 
1.218     brouard  2682:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2683:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2684:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2685: {
1.264     brouard  2686:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2687:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2688:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2689:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2690:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2691:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2692:   /* Initial matrix pimij */
                   2693:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2694:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2695:   /*  0,                   0                  , 1} */
                   2696:   /*
                   2697:    * and after some iteration: */
                   2698:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2699:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2700:   /*  0,                   0                  , 1} */
                   2701:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2702:   /* {0.51571254859325999, 0.4842874514067399, */
                   2703:   /*  0.51326036147820708, 0.48673963852179264} */
                   2704:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2705: 
                   2706:   int i, ii,j,k;
1.247     brouard  2707:   int first=0;
1.217     brouard  2708:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2709:   /* double **matprod2(); */ /* test */
                   2710:   double **out, cov[NCOVMAX+1], **bmij();
                   2711:   double **newm;
1.218     brouard  2712:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2713:   double        **oldm, **savm;  /* for use */
                   2714: 
1.217     brouard  2715:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2716:   int ncvloop=0;
                   2717:   
                   2718:   min=vector(1,nlstate);
                   2719:   max=vector(1,nlstate);
                   2720:   meandiff=vector(1,nlstate);
                   2721: 
1.266     brouard  2722:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2723:   oldm=oldms; savm=savms;
                   2724:   
                   2725:   /* Starting with matrix unity */
                   2726:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2727:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2728:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2729:     }
                   2730:   
                   2731:   cov[1]=1.;
                   2732:   
                   2733:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2734:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2735:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2736:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2737:     ncvloop++;
1.218     brouard  2738:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2739:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2740:     /* Covariates have to be included here again */
                   2741:     cov[2]=agefin;
                   2742:     if(nagesqr==1)
                   2743:       cov[3]= agefin*agefin;;
1.242     brouard  2744:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2745:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2746:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2747:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2748:     }
                   2749:     /* for (k=1; k<=cptcovn;k++) { */
                   2750:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2751:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2752:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2753:     /* } */
                   2754:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2755:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2756:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2757:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2758:     }
                   2759:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2760:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2761:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2762:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2763:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2764:       if(Dummy[Tvar[Tage[k]]]){
                   2765:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2766:       } else{
                   2767:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2768:       }
                   2769:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2770:     }
                   2771:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2772:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2773:       if(Dummy[Tvard[k][1]==0]){
                   2774:        if(Dummy[Tvard[k][2]==0]){
                   2775:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2776:        }else{
                   2777:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2778:        }
                   2779:       }else{
                   2780:        if(Dummy[Tvard[k][2]==0]){
                   2781:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2782:        }else{
                   2783:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2784:        }
                   2785:       }
1.217     brouard  2786:     }
                   2787:     
                   2788:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2789:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2790:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2791:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2792:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2793:                /* ij should be linked to the correct index of cov */
                   2794:                /* age and covariate values ij are in 'cov', but we need to pass
                   2795:                 * ij for the observed prevalence at age and status and covariate
                   2796:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2797:                 */
                   2798:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2799:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2800:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2801:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2802:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2803:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2804:     /*         printf("%d newm= ",i); */
                   2805:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2806:     /*           printf("%f ",newm[i][j]); */
                   2807:     /*         } */
                   2808:     /*         printf("oldm * "); */
                   2809:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2810:     /*           printf("%f ",oldm[i][j]); */
                   2811:     /*         } */
1.268     brouard  2812:     /*         printf(" bmmij "); */
1.266     brouard  2813:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2814:     /*           printf("%f ",pmmij[i][j]); */
                   2815:     /*         } */
                   2816:     /*         printf("\n"); */
                   2817:     /*   } */
                   2818:     /* } */
1.217     brouard  2819:     savm=oldm;
                   2820:     oldm=newm;
1.266     brouard  2821: 
1.217     brouard  2822:     for(j=1; j<=nlstate; j++){
                   2823:       max[j]=0.;
                   2824:       min[j]=1.;
                   2825:     }
                   2826:     for(j=1; j<=nlstate; j++){ 
                   2827:       for(i=1;i<=nlstate;i++){
1.234     brouard  2828:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2829:        bprlim[i][j]= newm[i][j];
                   2830:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2831:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2832:       }
                   2833:     }
1.218     brouard  2834:                
1.217     brouard  2835:     maxmax=0.;
                   2836:     for(i=1; i<=nlstate; i++){
                   2837:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2838:       maxmax=FMAX(maxmax,meandiff[i]);
                   2839:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2840:     } /* i loop */
1.217     brouard  2841:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2842:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2843:     if(maxmax < ftolpl){
1.220     brouard  2844:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2845:       free_vector(min,1,nlstate);
                   2846:       free_vector(max,1,nlstate);
                   2847:       free_vector(meandiff,1,nlstate);
                   2848:       return bprlim;
                   2849:     }
                   2850:   } /* age loop */
                   2851:     /* After some age loop it doesn't converge */
1.247     brouard  2852:   if(first){
                   2853:     first=1;
                   2854:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2855: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2856:   }
                   2857:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2858: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2859:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2860:   free_vector(min,1,nlstate);
                   2861:   free_vector(max,1,nlstate);
                   2862:   free_vector(meandiff,1,nlstate);
                   2863:   
                   2864:   return bprlim; /* should not reach here */
                   2865: }
                   2866: 
1.126     brouard  2867: /*************** transition probabilities ***************/ 
                   2868: 
                   2869: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2870: {
1.138     brouard  2871:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2872:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2873:      model to the ncovmodel covariates (including constant and age).
                   2874:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2875:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2876:      ncth covariate in the global vector x is given by the formula:
                   2877:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2878:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2879:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2880:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2881:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2882:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2883:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2884:   */
                   2885:   double s1, lnpijopii;
1.126     brouard  2886:   /*double t34;*/
1.164     brouard  2887:   int i,j, nc, ii, jj;
1.126     brouard  2888: 
1.223     brouard  2889:   for(i=1; i<= nlstate; i++){
                   2890:     for(j=1; j<i;j++){
                   2891:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2892:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2893:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2894:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2895:       }
                   2896:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2897:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2898:     }
                   2899:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2900:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2901:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2902:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2903:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2904:       }
                   2905:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2906:     }
                   2907:   }
1.218     brouard  2908:   
1.223     brouard  2909:   for(i=1; i<= nlstate; i++){
                   2910:     s1=0;
                   2911:     for(j=1; j<i; j++){
                   2912:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2913:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2914:     }
                   2915:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2916:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2917:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2918:     }
                   2919:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2920:     ps[i][i]=1./(s1+1.);
                   2921:     /* Computing other pijs */
                   2922:     for(j=1; j<i; j++)
                   2923:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2924:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2925:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2926:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2927:   } /* end i */
1.218     brouard  2928:   
1.223     brouard  2929:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2930:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2931:       ps[ii][jj]=0;
                   2932:       ps[ii][ii]=1;
                   2933:     }
                   2934:   }
1.218     brouard  2935:   
                   2936:   
1.223     brouard  2937:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2938:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2939:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2940:   /*   } */
                   2941:   /*   printf("\n "); */
                   2942:   /* } */
                   2943:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2944:   /*
                   2945:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2946:                goto end;*/
1.266     brouard  2947:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2948: }
                   2949: 
1.218     brouard  2950: /*************** backward transition probabilities ***************/ 
                   2951: 
                   2952:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2953: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2954:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2955: {
1.266     brouard  2956:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2957:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2958:    */
1.218     brouard  2959:   int i, ii, j,k;
1.222     brouard  2960:   
                   2961:   double **out, **pmij();
                   2962:   double sumnew=0.;
1.218     brouard  2963:   double agefin;
1.268     brouard  2964:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2965:   double **dnewm, **dsavm, **doldm;
                   2966:   double **bbmij;
                   2967:   
1.218     brouard  2968:   doldm=ddoldms; /* global pointers */
1.222     brouard  2969:   dnewm=ddnewms;
                   2970:   dsavm=ddsavms;
                   2971:   
                   2972:   agefin=cov[2];
1.268     brouard  2973:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2974:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2975:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2976:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2977: 
                   2978:   /* P_x */
1.266     brouard  2979:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2980:   /* outputs pmmij which is a stochastic matrix in row */
                   2981: 
                   2982:   /* Diag(w_x) */
                   2983:   /* Problem with prevacurrent which can be zero */
                   2984:   sumnew=0.;
1.269     brouard  2985:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2986:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2987:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2988:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2989:   }
                   2990:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2991:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2992:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2993:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2994:     }
                   2995:   }else{
                   2996:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2997:       for (j=1;j<=nlstate+ndeath;j++)
                   2998:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2999:     }
                   3000:     /* if(sumnew <0.9){ */
                   3001:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3002:     /* } */
                   3003:   }
                   3004:   k3=0.0;  /* We put the last diagonal to 0 */
                   3005:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3006:       doldm[ii][ii]= k3;
                   3007:   }
                   3008:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3009:   
                   3010:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3011:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3012: 
                   3013:   /* Diag(Sum_i w^i_x p^ij_x */
                   3014:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3015:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3016:     sumnew=0.;
1.222     brouard  3017:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3018:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3019:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3020:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3021:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3022:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3023:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3024:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3025:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3026:        /* }else */
1.268     brouard  3027:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3028:     } /*End ii */
                   3029:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3030: 
                   3031:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3032:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3033:   /* end bmij */
1.266     brouard  3034:   return ps; /*pointer is unchanged */
1.218     brouard  3035: }
1.217     brouard  3036: /*************** transition probabilities ***************/ 
                   3037: 
1.218     brouard  3038: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3039: {
                   3040:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3041:      computes the probability to be observed in state j being in state i by appying the
                   3042:      model to the ncovmodel covariates (including constant and age).
                   3043:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3044:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3045:      ncth covariate in the global vector x is given by the formula:
                   3046:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3047:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3048:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3049:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3050:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3051:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3052:   */
                   3053:   double s1, lnpijopii;
                   3054:   /*double t34;*/
                   3055:   int i,j, nc, ii, jj;
                   3056: 
1.234     brouard  3057:   for(i=1; i<= nlstate; i++){
                   3058:     for(j=1; j<i;j++){
                   3059:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3060:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3061:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3062:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3063:       }
                   3064:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3065:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3066:     }
                   3067:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3068:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3069:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3070:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3071:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3072:       }
                   3073:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3074:     }
                   3075:   }
                   3076:   
                   3077:   for(i=1; i<= nlstate; i++){
                   3078:     s1=0;
                   3079:     for(j=1; j<i; j++){
                   3080:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3081:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3082:     }
                   3083:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3084:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3085:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3086:     }
                   3087:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3088:     ps[i][i]=1./(s1+1.);
                   3089:     /* Computing other pijs */
                   3090:     for(j=1; j<i; j++)
                   3091:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3092:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3093:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3094:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3095:   } /* end i */
                   3096:   
                   3097:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3098:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3099:       ps[ii][jj]=0;
                   3100:       ps[ii][ii]=1;
                   3101:     }
                   3102:   }
                   3103:   /* Added for backcast */ /* Transposed matrix too */
                   3104:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3105:     s1=0.;
                   3106:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3107:       s1+=ps[ii][jj];
                   3108:     }
                   3109:     for(ii=1; ii<= nlstate; ii++){
                   3110:       ps[ii][jj]=ps[ii][jj]/s1;
                   3111:     }
                   3112:   }
                   3113:   /* Transposition */
                   3114:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3115:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3116:       s1=ps[ii][jj];
                   3117:       ps[ii][jj]=ps[jj][ii];
                   3118:       ps[jj][ii]=s1;
                   3119:     }
                   3120:   }
                   3121:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3122:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3123:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3124:   /*   } */
                   3125:   /*   printf("\n "); */
                   3126:   /* } */
                   3127:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3128:   /*
                   3129:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3130:     goto end;*/
                   3131:   return ps;
1.217     brouard  3132: }
                   3133: 
                   3134: 
1.126     brouard  3135: /**************** Product of 2 matrices ******************/
                   3136: 
1.145     brouard  3137: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3138: {
                   3139:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3140:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3141:   /* in, b, out are matrice of pointers which should have been initialized 
                   3142:      before: only the contents of out is modified. The function returns
                   3143:      a pointer to pointers identical to out */
1.145     brouard  3144:   int i, j, k;
1.126     brouard  3145:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3146:     for(k=ncolol; k<=ncoloh; k++){
                   3147:       out[i][k]=0.;
                   3148:       for(j=ncl; j<=nch; j++)
                   3149:        out[i][k] +=in[i][j]*b[j][k];
                   3150:     }
1.126     brouard  3151:   return out;
                   3152: }
                   3153: 
                   3154: 
                   3155: /************* Higher Matrix Product ***************/
                   3156: 
1.235     brouard  3157: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3158: {
1.218     brouard  3159:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3160:      'nhstepm*hstepm*stepm' months (i.e. until
                   3161:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3162:      nhstepm*hstepm matrices. 
                   3163:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3164:      (typically every 2 years instead of every month which is too big 
                   3165:      for the memory).
                   3166:      Model is determined by parameters x and covariates have to be 
                   3167:      included manually here. 
                   3168: 
                   3169:      */
                   3170: 
                   3171:   int i, j, d, h, k;
1.131     brouard  3172:   double **out, cov[NCOVMAX+1];
1.126     brouard  3173:   double **newm;
1.187     brouard  3174:   double agexact;
1.214     brouard  3175:   double agebegin, ageend;
1.126     brouard  3176: 
                   3177:   /* Hstepm could be zero and should return the unit matrix */
                   3178:   for (i=1;i<=nlstate+ndeath;i++)
                   3179:     for (j=1;j<=nlstate+ndeath;j++){
                   3180:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3181:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3182:     }
                   3183:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3184:   for(h=1; h <=nhstepm; h++){
                   3185:     for(d=1; d <=hstepm; d++){
                   3186:       newm=savm;
                   3187:       /* Covariates have to be included here again */
                   3188:       cov[1]=1.;
1.214     brouard  3189:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3190:       cov[2]=agexact;
                   3191:       if(nagesqr==1)
1.227     brouard  3192:        cov[3]= agexact*agexact;
1.235     brouard  3193:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3194:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3195:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3196:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3197:       }
                   3198:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3199:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3200:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3201:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3202:       }
                   3203:       for (k=1; k<=cptcovage;k++){
                   3204:        if(Dummy[Tvar[Tage[k]]]){
                   3205:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3206:        } else{
                   3207:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3208:        }
                   3209:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3210:       }
                   3211:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3212:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3213:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3214:       }
                   3215:       /* for (k=1; k<=cptcovn;k++)  */
                   3216:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3217:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3218:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3219:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3220:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3221:       
                   3222:       
1.126     brouard  3223:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3224:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3225:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3226:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3227:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3228:       /* if((int)age == 70){ */
                   3229:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3230:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3231:       /*         printf("%d pmmij ",i); */
                   3232:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3233:       /*           printf("%f ",pmmij[i][j]); */
                   3234:       /*         } */
                   3235:       /*         printf(" oldm "); */
                   3236:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3237:       /*           printf("%f ",oldm[i][j]); */
                   3238:       /*         } */
                   3239:       /*         printf("\n"); */
                   3240:       /*       } */
                   3241:       /* } */
1.126     brouard  3242:       savm=oldm;
                   3243:       oldm=newm;
                   3244:     }
                   3245:     for(i=1; i<=nlstate+ndeath; i++)
                   3246:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3247:        po[i][j][h]=newm[i][j];
                   3248:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3249:       }
1.128     brouard  3250:     /*printf("h=%d ",h);*/
1.126     brouard  3251:   } /* end h */
1.267     brouard  3252:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3253:   return po;
                   3254: }
                   3255: 
1.217     brouard  3256: /************* Higher Back Matrix Product ***************/
1.218     brouard  3257: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3258: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3259: {
1.266     brouard  3260:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3261:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3262:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3263:      nhstepm*hstepm matrices.
                   3264:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3265:      (typically every 2 years instead of every month which is too big
1.217     brouard  3266:      for the memory).
1.218     brouard  3267:      Model is determined by parameters x and covariates have to be
1.266     brouard  3268:      included manually here. Then we use a call to bmij(x and cov)
                   3269:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3270:   */
1.217     brouard  3271: 
                   3272:   int i, j, d, h, k;
1.266     brouard  3273:   double **out, cov[NCOVMAX+1], **bmij();
                   3274:   double **newm, ***newmm;
1.217     brouard  3275:   double agexact;
                   3276:   double agebegin, ageend;
1.222     brouard  3277:   double **oldm, **savm;
1.217     brouard  3278: 
1.266     brouard  3279:   newmm=po; /* To be saved */
                   3280:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3281:   /* Hstepm could be zero and should return the unit matrix */
                   3282:   for (i=1;i<=nlstate+ndeath;i++)
                   3283:     for (j=1;j<=nlstate+ndeath;j++){
                   3284:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3285:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3286:     }
                   3287:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3288:   for(h=1; h <=nhstepm; h++){
                   3289:     for(d=1; d <=hstepm; d++){
                   3290:       newm=savm;
                   3291:       /* Covariates have to be included here again */
                   3292:       cov[1]=1.;
1.271     brouard  3293:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3294:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3295:       cov[2]=agexact;
                   3296:       if(nagesqr==1)
1.222     brouard  3297:        cov[3]= agexact*agexact;
1.266     brouard  3298:       for (k=1; k<=cptcovn;k++){
                   3299:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3300:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3301:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3302:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3303:       }
1.267     brouard  3304:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3305:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3306:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3307:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3308:       }
                   3309:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3310:        if(Dummy[Tvar[Tage[k]]]){
                   3311:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3312:        } else{
                   3313:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3314:        }
                   3315:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3316:       }
                   3317:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3318:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3319:       }                        
1.217     brouard  3320:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3321:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3322: 
1.218     brouard  3323:       /* Careful transposed matrix */
1.266     brouard  3324:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3325:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3326:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3327:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3328:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3329:       /* if((int)age == 70){ */
                   3330:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3331:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3332:       /*         printf("%d pmmij ",i); */
                   3333:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3334:       /*           printf("%f ",pmmij[i][j]); */
                   3335:       /*         } */
                   3336:       /*         printf(" oldm "); */
                   3337:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3338:       /*           printf("%f ",oldm[i][j]); */
                   3339:       /*         } */
                   3340:       /*         printf("\n"); */
                   3341:       /*       } */
                   3342:       /* } */
                   3343:       savm=oldm;
                   3344:       oldm=newm;
                   3345:     }
                   3346:     for(i=1; i<=nlstate+ndeath; i++)
                   3347:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3348:        po[i][j][h]=newm[i][j];
1.268     brouard  3349:        /* if(h==nhstepm) */
                   3350:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3351:       }
1.268     brouard  3352:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3353:   } /* end h */
1.268     brouard  3354:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3355:   return po;
                   3356: }
                   3357: 
                   3358: 
1.162     brouard  3359: #ifdef NLOPT
                   3360:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3361:   double fret;
                   3362:   double *xt;
                   3363:   int j;
                   3364:   myfunc_data *d2 = (myfunc_data *) pd;
                   3365: /* xt = (p1-1); */
                   3366:   xt=vector(1,n); 
                   3367:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3368: 
                   3369:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3370:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3371:   printf("Function = %.12lf ",fret);
                   3372:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3373:   printf("\n");
                   3374:  free_vector(xt,1,n);
                   3375:   return fret;
                   3376: }
                   3377: #endif
1.126     brouard  3378: 
                   3379: /*************** log-likelihood *************/
                   3380: double func( double *x)
                   3381: {
1.226     brouard  3382:   int i, ii, j, k, mi, d, kk;
                   3383:   int ioffset=0;
                   3384:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3385:   double **out;
                   3386:   double lli; /* Individual log likelihood */
                   3387:   int s1, s2;
1.228     brouard  3388:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3389:   double bbh, survp;
                   3390:   long ipmx;
                   3391:   double agexact;
                   3392:   /*extern weight */
                   3393:   /* We are differentiating ll according to initial status */
                   3394:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3395:   /*for(i=1;i<imx;i++) 
                   3396:     printf(" %d\n",s[4][i]);
                   3397:   */
1.162     brouard  3398: 
1.226     brouard  3399:   ++countcallfunc;
1.162     brouard  3400: 
1.226     brouard  3401:   cov[1]=1.;
1.126     brouard  3402: 
1.226     brouard  3403:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3404:   ioffset=0;
1.226     brouard  3405:   if(mle==1){
                   3406:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3407:       /* Computes the values of the ncovmodel covariates of the model
                   3408:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3409:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3410:         to be observed in j being in i according to the model.
                   3411:       */
1.243     brouard  3412:       ioffset=2+nagesqr ;
1.233     brouard  3413:    /* Fixed */
1.234     brouard  3414:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3415:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3416:       }
1.226     brouard  3417:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3418:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3419:         has been calculated etc */
                   3420:       /* For an individual i, wav[i] gives the number of effective waves */
                   3421:       /* We compute the contribution to Likelihood of each effective transition
                   3422:         mw[mi][i] is real wave of the mi th effectve wave */
                   3423:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3424:         s2=s[mw[mi+1][i]][i];
                   3425:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3426:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3427:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3428:       */
                   3429:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3430:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3431:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3432:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3433:        }
                   3434:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3435:          for (j=1;j<=nlstate+ndeath;j++){
                   3436:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3437:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3438:          }
                   3439:        for(d=0; d<dh[mi][i]; d++){
                   3440:          newm=savm;
                   3441:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3442:          cov[2]=agexact;
                   3443:          if(nagesqr==1)
                   3444:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3445:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3446:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3447:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3448:          else
                   3449:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3450:          }
                   3451:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3452:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3453:          savm=oldm;
                   3454:          oldm=newm;
                   3455:        } /* end mult */
                   3456:        
                   3457:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3458:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3459:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3460:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3461:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3462:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3463:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3464:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3465:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3466:                                 * -stepm/2 to stepm/2 .
                   3467:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3468:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3469:                                 */
1.234     brouard  3470:        s1=s[mw[mi][i]][i];
                   3471:        s2=s[mw[mi+1][i]][i];
                   3472:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3473:        /* bias bh is positive if real duration
                   3474:         * is higher than the multiple of stepm and negative otherwise.
                   3475:         */
                   3476:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3477:        if( s2 > nlstate){ 
                   3478:          /* i.e. if s2 is a death state and if the date of death is known 
                   3479:             then the contribution to the likelihood is the probability to 
                   3480:             die between last step unit time and current  step unit time, 
                   3481:             which is also equal to probability to die before dh 
                   3482:             minus probability to die before dh-stepm . 
                   3483:             In version up to 0.92 likelihood was computed
                   3484:             as if date of death was unknown. Death was treated as any other
                   3485:             health state: the date of the interview describes the actual state
                   3486:             and not the date of a change in health state. The former idea was
                   3487:             to consider that at each interview the state was recorded
                   3488:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3489:             introduced the exact date of death then we should have modified
                   3490:             the contribution of an exact death to the likelihood. This new
                   3491:             contribution is smaller and very dependent of the step unit
                   3492:             stepm. It is no more the probability to die between last interview
                   3493:             and month of death but the probability to survive from last
                   3494:             interview up to one month before death multiplied by the
                   3495:             probability to die within a month. Thanks to Chris
                   3496:             Jackson for correcting this bug.  Former versions increased
                   3497:             mortality artificially. The bad side is that we add another loop
                   3498:             which slows down the processing. The difference can be up to 10%
                   3499:             lower mortality.
                   3500:          */
                   3501:          /* If, at the beginning of the maximization mostly, the
                   3502:             cumulative probability or probability to be dead is
                   3503:             constant (ie = 1) over time d, the difference is equal to
                   3504:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3505:             s1 at precedent wave, to be dead a month before current
                   3506:             wave is equal to probability, being at state s1 at
                   3507:             precedent wave, to be dead at mont of the current
                   3508:             wave. Then the observed probability (that this person died)
                   3509:             is null according to current estimated parameter. In fact,
                   3510:             it should be very low but not zero otherwise the log go to
                   3511:             infinity.
                   3512:          */
1.183     brouard  3513: /* #ifdef INFINITYORIGINAL */
                   3514: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3515: /* #else */
                   3516: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3517: /*         lli=log(mytinydouble); */
                   3518: /*       else */
                   3519: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3520: /* #endif */
1.226     brouard  3521:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3522:          
1.226     brouard  3523:        } else if  ( s2==-1 ) { /* alive */
                   3524:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3525:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3526:          /*survp += out[s1][j]; */
                   3527:          lli= log(survp);
                   3528:        }
                   3529:        else if  (s2==-4) { 
                   3530:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3531:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3532:          lli= log(survp); 
                   3533:        } 
                   3534:        else if  (s2==-5) { 
                   3535:          for (j=1,survp=0. ; j<=2; j++)  
                   3536:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3537:          lli= log(survp); 
                   3538:        } 
                   3539:        else{
                   3540:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3541:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3542:        } 
                   3543:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3544:        /*if(lli ==000.0)*/
                   3545:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3546:        ipmx +=1;
                   3547:        sw += weight[i];
                   3548:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3549:        /* if (lli < log(mytinydouble)){ */
                   3550:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3551:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3552:        /* } */
                   3553:       } /* end of wave */
                   3554:     } /* end of individual */
                   3555:   }  else if(mle==2){
                   3556:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3557:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3558:       for(mi=1; mi<= wav[i]-1; mi++){
                   3559:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3560:          for (j=1;j<=nlstate+ndeath;j++){
                   3561:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3562:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3563:          }
                   3564:        for(d=0; d<=dh[mi][i]; d++){
                   3565:          newm=savm;
                   3566:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3567:          cov[2]=agexact;
                   3568:          if(nagesqr==1)
                   3569:            cov[3]= agexact*agexact;
                   3570:          for (kk=1; kk<=cptcovage;kk++) {
                   3571:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3572:          }
                   3573:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3574:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3575:          savm=oldm;
                   3576:          oldm=newm;
                   3577:        } /* end mult */
                   3578:       
                   3579:        s1=s[mw[mi][i]][i];
                   3580:        s2=s[mw[mi+1][i]][i];
                   3581:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3582:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3583:        ipmx +=1;
                   3584:        sw += weight[i];
                   3585:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3586:       } /* end of wave */
                   3587:     } /* end of individual */
                   3588:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3589:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3590:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3591:       for(mi=1; mi<= wav[i]-1; mi++){
                   3592:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3593:          for (j=1;j<=nlstate+ndeath;j++){
                   3594:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3595:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3596:          }
                   3597:        for(d=0; d<dh[mi][i]; d++){
                   3598:          newm=savm;
                   3599:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3600:          cov[2]=agexact;
                   3601:          if(nagesqr==1)
                   3602:            cov[3]= agexact*agexact;
                   3603:          for (kk=1; kk<=cptcovage;kk++) {
                   3604:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3605:          }
                   3606:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3607:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3608:          savm=oldm;
                   3609:          oldm=newm;
                   3610:        } /* end mult */
                   3611:       
                   3612:        s1=s[mw[mi][i]][i];
                   3613:        s2=s[mw[mi+1][i]][i];
                   3614:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3615:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3616:        ipmx +=1;
                   3617:        sw += weight[i];
                   3618:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3619:       } /* end of wave */
                   3620:     } /* end of individual */
                   3621:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3622:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3623:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3624:       for(mi=1; mi<= wav[i]-1; mi++){
                   3625:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3626:          for (j=1;j<=nlstate+ndeath;j++){
                   3627:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3628:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3629:          }
                   3630:        for(d=0; d<dh[mi][i]; d++){
                   3631:          newm=savm;
                   3632:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3633:          cov[2]=agexact;
                   3634:          if(nagesqr==1)
                   3635:            cov[3]= agexact*agexact;
                   3636:          for (kk=1; kk<=cptcovage;kk++) {
                   3637:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3638:          }
1.126     brouard  3639:        
1.226     brouard  3640:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3641:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3642:          savm=oldm;
                   3643:          oldm=newm;
                   3644:        } /* end mult */
                   3645:       
                   3646:        s1=s[mw[mi][i]][i];
                   3647:        s2=s[mw[mi+1][i]][i];
                   3648:        if( s2 > nlstate){ 
                   3649:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3650:        } else if  ( s2==-1 ) { /* alive */
                   3651:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3652:            survp += out[s1][j];
                   3653:          lli= log(survp);
                   3654:        }else{
                   3655:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3656:        }
                   3657:        ipmx +=1;
                   3658:        sw += weight[i];
                   3659:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3660: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3661:       } /* end of wave */
                   3662:     } /* end of individual */
                   3663:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3664:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3665:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3666:       for(mi=1; mi<= wav[i]-1; mi++){
                   3667:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3668:          for (j=1;j<=nlstate+ndeath;j++){
                   3669:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3670:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3671:          }
                   3672:        for(d=0; d<dh[mi][i]; d++){
                   3673:          newm=savm;
                   3674:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3675:          cov[2]=agexact;
                   3676:          if(nagesqr==1)
                   3677:            cov[3]= agexact*agexact;
                   3678:          for (kk=1; kk<=cptcovage;kk++) {
                   3679:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3680:          }
1.126     brouard  3681:        
1.226     brouard  3682:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3683:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3684:          savm=oldm;
                   3685:          oldm=newm;
                   3686:        } /* end mult */
                   3687:       
                   3688:        s1=s[mw[mi][i]][i];
                   3689:        s2=s[mw[mi+1][i]][i];
                   3690:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3691:        ipmx +=1;
                   3692:        sw += weight[i];
                   3693:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3694:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3695:       } /* end of wave */
                   3696:     } /* end of individual */
                   3697:   } /* End of if */
                   3698:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3699:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3700:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3701:   return -l;
1.126     brouard  3702: }
                   3703: 
                   3704: /*************** log-likelihood *************/
                   3705: double funcone( double *x)
                   3706: {
1.228     brouard  3707:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3708:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3709:   int ioffset=0;
1.131     brouard  3710:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3711:   double **out;
                   3712:   double lli; /* Individual log likelihood */
                   3713:   double llt;
                   3714:   int s1, s2;
1.228     brouard  3715:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3716: 
1.126     brouard  3717:   double bbh, survp;
1.187     brouard  3718:   double agexact;
1.214     brouard  3719:   double agebegin, ageend;
1.126     brouard  3720:   /*extern weight */
                   3721:   /* We are differentiating ll according to initial status */
                   3722:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3723:   /*for(i=1;i<imx;i++) 
                   3724:     printf(" %d\n",s[4][i]);
                   3725:   */
                   3726:   cov[1]=1.;
                   3727: 
                   3728:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3729:   ioffset=0;
                   3730:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3731:     /* ioffset=2+nagesqr+cptcovage; */
                   3732:     ioffset=2+nagesqr;
1.232     brouard  3733:     /* Fixed */
1.224     brouard  3734:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3735:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3736:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3737:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3738: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3739: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3740: /*    cov[2+6]=covar[2][i]; V2  */
                   3741: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3742: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3743: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3744: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3745: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3746: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3747:     }
1.232     brouard  3748:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3749:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3750:     /* } */
1.231     brouard  3751:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3752:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3753:     /* } */
1.225     brouard  3754:     
1.233     brouard  3755: 
                   3756:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3757:     /* Wave varying (but not age varying) */
                   3758:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3759:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3760:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3761:       }
1.232     brouard  3762:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3763:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3764:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3765:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3766:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3767:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3768:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3769:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3770:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3771:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3772:       /* } */
1.126     brouard  3773:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3774:        for (j=1;j<=nlstate+ndeath;j++){
                   3775:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3776:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3777:        }
1.214     brouard  3778:       
                   3779:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3780:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3781:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3782:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3783:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3784:          and mw[mi+1][i]. dh depends on stepm.*/
                   3785:        newm=savm;
1.247     brouard  3786:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3787:        cov[2]=agexact;
                   3788:        if(nagesqr==1)
                   3789:          cov[3]= agexact*agexact;
                   3790:        for (kk=1; kk<=cptcovage;kk++) {
                   3791:          if(!FixedV[Tvar[Tage[kk]]])
                   3792:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3793:          else
                   3794:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3795:        }
                   3796:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3797:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3798:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3799:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3800:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3801:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3802:        savm=oldm;
                   3803:        oldm=newm;
1.126     brouard  3804:       } /* end mult */
                   3805:       
                   3806:       s1=s[mw[mi][i]][i];
                   3807:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3808:       /* if(s2==-1){ */
1.268     brouard  3809:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3810:       /*       /\* exit(1); *\/ */
                   3811:       /* } */
1.126     brouard  3812:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3813:       /* bias is positive if real duration
                   3814:        * is higher than the multiple of stepm and negative otherwise.
                   3815:        */
                   3816:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3817:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3818:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3819:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3820:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3821:        lli= log(survp);
1.126     brouard  3822:       }else if (mle==1){
1.242     brouard  3823:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3824:       } else if(mle==2){
1.242     brouard  3825:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3826:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3827:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3828:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3829:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3830:       } else{  /* mle=0 back to 1 */
1.242     brouard  3831:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3832:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3833:       } /* End of if */
                   3834:       ipmx +=1;
                   3835:       sw += weight[i];
                   3836:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3837:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3838:       if(globpr){
1.246     brouard  3839:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3840:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3841:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3842:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3843:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3844:          llt +=ll[k]*gipmx/gsw;
                   3845:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3846:        }
                   3847:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3848:       }
1.232     brouard  3849:        } /* end of wave */
                   3850: } /* end of individual */
                   3851: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3852: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3853: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3854: if(globpr==0){ /* First time we count the contributions and weights */
                   3855:        gipmx=ipmx;
                   3856:        gsw=sw;
                   3857: }
                   3858: return -l;
1.126     brouard  3859: }
                   3860: 
                   3861: 
                   3862: /*************** function likelione ***********/
                   3863: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3864: {
                   3865:   /* This routine should help understanding what is done with 
                   3866:      the selection of individuals/waves and
                   3867:      to check the exact contribution to the likelihood.
                   3868:      Plotting could be done.
                   3869:    */
                   3870:   int k;
                   3871: 
                   3872:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3873:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3874:     strcat(fileresilk,fileresu);
1.126     brouard  3875:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3876:       printf("Problem with resultfile: %s\n", fileresilk);
                   3877:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3878:     }
1.214     brouard  3879:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3880:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3881:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3882:     for(k=1; k<=nlstate; k++) 
                   3883:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3884:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3885:   }
                   3886: 
                   3887:   *fretone=(*funcone)(p);
                   3888:   if(*globpri !=0){
                   3889:     fclose(ficresilk);
1.205     brouard  3890:     if (mle ==0)
                   3891:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3892:     else if(mle >=1)
                   3893:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3894:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3895:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3896:       
                   3897:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3898:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3899: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3900:     }
1.207     brouard  3901:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3902: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3903:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3904: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3905:     fflush(fichtm);
1.205     brouard  3906:   }
1.126     brouard  3907:   return;
                   3908: }
                   3909: 
                   3910: 
                   3911: /*********** Maximum Likelihood Estimation ***************/
                   3912: 
                   3913: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3914: {
1.165     brouard  3915:   int i,j, iter=0;
1.126     brouard  3916:   double **xi;
                   3917:   double fret;
                   3918:   double fretone; /* Only one call to likelihood */
                   3919:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3920: 
                   3921: #ifdef NLOPT
                   3922:   int creturn;
                   3923:   nlopt_opt opt;
                   3924:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3925:   double *lb;
                   3926:   double minf; /* the minimum objective value, upon return */
                   3927:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3928:   myfunc_data dinst, *d = &dinst;
                   3929: #endif
                   3930: 
                   3931: 
1.126     brouard  3932:   xi=matrix(1,npar,1,npar);
                   3933:   for (i=1;i<=npar;i++)
                   3934:     for (j=1;j<=npar;j++)
                   3935:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3936:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3937:   strcpy(filerespow,"POW_"); 
1.126     brouard  3938:   strcat(filerespow,fileres);
                   3939:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3940:     printf("Problem with resultfile: %s\n", filerespow);
                   3941:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3942:   }
                   3943:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3944:   for (i=1;i<=nlstate;i++)
                   3945:     for(j=1;j<=nlstate+ndeath;j++)
                   3946:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3947:   fprintf(ficrespow,"\n");
1.162     brouard  3948: #ifdef POWELL
1.126     brouard  3949:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3950: #endif
1.126     brouard  3951: 
1.162     brouard  3952: #ifdef NLOPT
                   3953: #ifdef NEWUOA
                   3954:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3955: #else
                   3956:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3957: #endif
                   3958:   lb=vector(0,npar-1);
                   3959:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3960:   nlopt_set_lower_bounds(opt, lb);
                   3961:   nlopt_set_initial_step1(opt, 0.1);
                   3962:   
                   3963:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3964:   d->function = func;
                   3965:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3966:   nlopt_set_min_objective(opt, myfunc, d);
                   3967:   nlopt_set_xtol_rel(opt, ftol);
                   3968:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3969:     printf("nlopt failed! %d\n",creturn); 
                   3970:   }
                   3971:   else {
                   3972:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3973:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3974:     iter=1; /* not equal */
                   3975:   }
                   3976:   nlopt_destroy(opt);
                   3977: #endif
1.126     brouard  3978:   free_matrix(xi,1,npar,1,npar);
                   3979:   fclose(ficrespow);
1.203     brouard  3980:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3981:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3982:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3983: 
                   3984: }
                   3985: 
                   3986: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3987: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3988: {
                   3989:   double  **a,**y,*x,pd;
1.203     brouard  3990:   /* double **hess; */
1.164     brouard  3991:   int i, j;
1.126     brouard  3992:   int *indx;
                   3993: 
                   3994:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3995:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3996:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3997:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3998:   double gompertz(double p[]);
1.203     brouard  3999:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4000: 
                   4001:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4002:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4003:   for (i=1;i<=npar;i++){
1.203     brouard  4004:     printf("%d-",i);fflush(stdout);
                   4005:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4006:    
                   4007:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4008:     
                   4009:     /*  printf(" %f ",p[i]);
                   4010:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4011:   }
                   4012:   
                   4013:   for (i=1;i<=npar;i++) {
                   4014:     for (j=1;j<=npar;j++)  {
                   4015:       if (j>i) { 
1.203     brouard  4016:        printf(".%d-%d",i,j);fflush(stdout);
                   4017:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4018:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4019:        
                   4020:        hess[j][i]=hess[i][j];    
                   4021:        /*printf(" %lf ",hess[i][j]);*/
                   4022:       }
                   4023:     }
                   4024:   }
                   4025:   printf("\n");
                   4026:   fprintf(ficlog,"\n");
                   4027: 
                   4028:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4029:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4030:   
                   4031:   a=matrix(1,npar,1,npar);
                   4032:   y=matrix(1,npar,1,npar);
                   4033:   x=vector(1,npar);
                   4034:   indx=ivector(1,npar);
                   4035:   for (i=1;i<=npar;i++)
                   4036:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4037:   ludcmp(a,npar,indx,&pd);
                   4038: 
                   4039:   for (j=1;j<=npar;j++) {
                   4040:     for (i=1;i<=npar;i++) x[i]=0;
                   4041:     x[j]=1;
                   4042:     lubksb(a,npar,indx,x);
                   4043:     for (i=1;i<=npar;i++){ 
                   4044:       matcov[i][j]=x[i];
                   4045:     }
                   4046:   }
                   4047: 
                   4048:   printf("\n#Hessian matrix#\n");
                   4049:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4050:   for (i=1;i<=npar;i++) { 
                   4051:     for (j=1;j<=npar;j++) { 
1.203     brouard  4052:       printf("%.6e ",hess[i][j]);
                   4053:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4054:     }
                   4055:     printf("\n");
                   4056:     fprintf(ficlog,"\n");
                   4057:   }
                   4058: 
1.203     brouard  4059:   /* printf("\n#Covariance matrix#\n"); */
                   4060:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4061:   /* for (i=1;i<=npar;i++) {  */
                   4062:   /*   for (j=1;j<=npar;j++) {  */
                   4063:   /*     printf("%.6e ",matcov[i][j]); */
                   4064:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4065:   /*   } */
                   4066:   /*   printf("\n"); */
                   4067:   /*   fprintf(ficlog,"\n"); */
                   4068:   /* } */
                   4069: 
1.126     brouard  4070:   /* Recompute Inverse */
1.203     brouard  4071:   /* for (i=1;i<=npar;i++) */
                   4072:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4073:   /* ludcmp(a,npar,indx,&pd); */
                   4074: 
                   4075:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4076: 
                   4077:   /* for (j=1;j<=npar;j++) { */
                   4078:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4079:   /*   x[j]=1; */
                   4080:   /*   lubksb(a,npar,indx,x); */
                   4081:   /*   for (i=1;i<=npar;i++){  */
                   4082:   /*     y[i][j]=x[i]; */
                   4083:   /*     printf("%.3e ",y[i][j]); */
                   4084:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4085:   /*   } */
                   4086:   /*   printf("\n"); */
                   4087:   /*   fprintf(ficlog,"\n"); */
                   4088:   /* } */
                   4089: 
                   4090:   /* Verifying the inverse matrix */
                   4091: #ifdef DEBUGHESS
                   4092:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4093: 
1.203     brouard  4094:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4095:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4096: 
                   4097:   for (j=1;j<=npar;j++) {
                   4098:     for (i=1;i<=npar;i++){ 
1.203     brouard  4099:       printf("%.2f ",y[i][j]);
                   4100:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4101:     }
                   4102:     printf("\n");
                   4103:     fprintf(ficlog,"\n");
                   4104:   }
1.203     brouard  4105: #endif
1.126     brouard  4106: 
                   4107:   free_matrix(a,1,npar,1,npar);
                   4108:   free_matrix(y,1,npar,1,npar);
                   4109:   free_vector(x,1,npar);
                   4110:   free_ivector(indx,1,npar);
1.203     brouard  4111:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4112: 
                   4113: 
                   4114: }
                   4115: 
                   4116: /*************** hessian matrix ****************/
                   4117: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4118: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4119:   int i;
                   4120:   int l=1, lmax=20;
1.203     brouard  4121:   double k1,k2, res, fx;
1.132     brouard  4122:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4123:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4124:   int k=0,kmax=10;
                   4125:   double l1;
                   4126: 
                   4127:   fx=func(x);
                   4128:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4129:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4130:     l1=pow(10,l);
                   4131:     delts=delt;
                   4132:     for(k=1 ; k <kmax; k=k+1){
                   4133:       delt = delta*(l1*k);
                   4134:       p2[theta]=x[theta] +delt;
1.145     brouard  4135:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4136:       p2[theta]=x[theta]-delt;
                   4137:       k2=func(p2)-fx;
                   4138:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4139:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4140:       
1.203     brouard  4141: #ifdef DEBUGHESSII
1.126     brouard  4142:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4143:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4144: #endif
                   4145:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4146:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4147:        k=kmax;
                   4148:       }
                   4149:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4150:        k=kmax; l=lmax*10;
1.126     brouard  4151:       }
                   4152:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4153:        delts=delt;
                   4154:       }
1.203     brouard  4155:     } /* End loop k */
1.126     brouard  4156:   }
                   4157:   delti[theta]=delts;
                   4158:   return res; 
                   4159:   
                   4160: }
                   4161: 
1.203     brouard  4162: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4163: {
                   4164:   int i;
1.164     brouard  4165:   int l=1, lmax=20;
1.126     brouard  4166:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4167:   double p2[MAXPARM+1];
1.203     brouard  4168:   int k, kmax=1;
                   4169:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4170: 
                   4171:   int firstime=0;
1.203     brouard  4172:   
1.126     brouard  4173:   fx=func(x);
1.203     brouard  4174:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4175:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4176:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4177:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4178:     k1=func(p2)-fx;
                   4179:   
1.203     brouard  4180:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4181:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4182:     k2=func(p2)-fx;
                   4183:   
1.203     brouard  4184:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4185:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4186:     k3=func(p2)-fx;
                   4187:   
1.203     brouard  4188:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4189:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4190:     k4=func(p2)-fx;
1.203     brouard  4191:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4192:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4193:       firstime=1;
1.203     brouard  4194:       kmax=kmax+10;
1.208     brouard  4195:     }
                   4196:     if(kmax >=10 || firstime ==1){
1.246     brouard  4197:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4198:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4199:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4200:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4201:     }
                   4202: #ifdef DEBUGHESSIJ
                   4203:     v1=hess[thetai][thetai];
                   4204:     v2=hess[thetaj][thetaj];
                   4205:     cv12=res;
                   4206:     /* Computing eigen value of Hessian matrix */
                   4207:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4208:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4209:     if ((lc2 <0) || (lc1 <0) ){
                   4210:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4211:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4212:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4213:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4214:     }
1.126     brouard  4215: #endif
                   4216:   }
                   4217:   return res;
                   4218: }
                   4219: 
1.203     brouard  4220:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4221: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4222: /* { */
                   4223: /*   int i; */
                   4224: /*   int l=1, lmax=20; */
                   4225: /*   double k1,k2,k3,k4,res,fx; */
                   4226: /*   double p2[MAXPARM+1]; */
                   4227: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4228: /*   int k=0,kmax=10; */
                   4229: /*   double l1; */
                   4230:   
                   4231: /*   fx=func(x); */
                   4232: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4233: /*     l1=pow(10,l); */
                   4234: /*     delts=delt; */
                   4235: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4236: /*       delt = delti*(l1*k); */
                   4237: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4238: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4239: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4240: /*       k1=func(p2)-fx; */
                   4241:       
                   4242: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4243: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4244: /*       k2=func(p2)-fx; */
                   4245:       
                   4246: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4247: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4248: /*       k3=func(p2)-fx; */
                   4249:       
                   4250: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4251: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4252: /*       k4=func(p2)-fx; */
                   4253: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4254: /* #ifdef DEBUGHESSIJ */
                   4255: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4256: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4257: /* #endif */
                   4258: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4259: /*     k=kmax; */
                   4260: /*       } */
                   4261: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4262: /*     k=kmax; l=lmax*10; */
                   4263: /*       } */
                   4264: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4265: /*     delts=delt; */
                   4266: /*       } */
                   4267: /*     } /\* End loop k *\/ */
                   4268: /*   } */
                   4269: /*   delti[theta]=delts; */
                   4270: /*   return res;  */
                   4271: /* } */
                   4272: 
                   4273: 
1.126     brouard  4274: /************** Inverse of matrix **************/
                   4275: void ludcmp(double **a, int n, int *indx, double *d) 
                   4276: { 
                   4277:   int i,imax,j,k; 
                   4278:   double big,dum,sum,temp; 
                   4279:   double *vv; 
                   4280:  
                   4281:   vv=vector(1,n); 
                   4282:   *d=1.0; 
                   4283:   for (i=1;i<=n;i++) { 
                   4284:     big=0.0; 
                   4285:     for (j=1;j<=n;j++) 
                   4286:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4287:     if (big == 0.0){
                   4288:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4289:       for (j=1;j<=n;j++) {
                   4290:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4291:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4292:       }
                   4293:       fflush(ficlog);
                   4294:       fclose(ficlog);
                   4295:       nrerror("Singular matrix in routine ludcmp"); 
                   4296:     }
1.126     brouard  4297:     vv[i]=1.0/big; 
                   4298:   } 
                   4299:   for (j=1;j<=n;j++) { 
                   4300:     for (i=1;i<j;i++) { 
                   4301:       sum=a[i][j]; 
                   4302:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4303:       a[i][j]=sum; 
                   4304:     } 
                   4305:     big=0.0; 
                   4306:     for (i=j;i<=n;i++) { 
                   4307:       sum=a[i][j]; 
                   4308:       for (k=1;k<j;k++) 
                   4309:        sum -= a[i][k]*a[k][j]; 
                   4310:       a[i][j]=sum; 
                   4311:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4312:        big=dum; 
                   4313:        imax=i; 
                   4314:       } 
                   4315:     } 
                   4316:     if (j != imax) { 
                   4317:       for (k=1;k<=n;k++) { 
                   4318:        dum=a[imax][k]; 
                   4319:        a[imax][k]=a[j][k]; 
                   4320:        a[j][k]=dum; 
                   4321:       } 
                   4322:       *d = -(*d); 
                   4323:       vv[imax]=vv[j]; 
                   4324:     } 
                   4325:     indx[j]=imax; 
                   4326:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4327:     if (j != n) { 
                   4328:       dum=1.0/(a[j][j]); 
                   4329:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4330:     } 
                   4331:   } 
                   4332:   free_vector(vv,1,n);  /* Doesn't work */
                   4333: ;
                   4334: } 
                   4335: 
                   4336: void lubksb(double **a, int n, int *indx, double b[]) 
                   4337: { 
                   4338:   int i,ii=0,ip,j; 
                   4339:   double sum; 
                   4340:  
                   4341:   for (i=1;i<=n;i++) { 
                   4342:     ip=indx[i]; 
                   4343:     sum=b[ip]; 
                   4344:     b[ip]=b[i]; 
                   4345:     if (ii) 
                   4346:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4347:     else if (sum) ii=i; 
                   4348:     b[i]=sum; 
                   4349:   } 
                   4350:   for (i=n;i>=1;i--) { 
                   4351:     sum=b[i]; 
                   4352:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4353:     b[i]=sum/a[i][i]; 
                   4354:   } 
                   4355: } 
                   4356: 
                   4357: void pstamp(FILE *fichier)
                   4358: {
1.196     brouard  4359:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4360: }
                   4361: 
1.253     brouard  4362: 
                   4363: 
1.126     brouard  4364: /************ Frequencies ********************/
1.251     brouard  4365: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4366:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4367:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4368: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4369:   
1.265     brouard  4370:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4371:   int iind=0, iage=0;
                   4372:   int mi; /* Effective wave */
                   4373:   int first;
                   4374:   double ***freq; /* Frequencies */
1.268     brouard  4375:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4376:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4377:   double *meanq, *stdq, *idq;
1.226     brouard  4378:   double **meanqt;
                   4379:   double *pp, **prop, *posprop, *pospropt;
                   4380:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4381:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4382:   double agebegin, ageend;
                   4383:     
                   4384:   pp=vector(1,nlstate);
1.251     brouard  4385:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4386:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4387:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4388:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4389:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4390:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4391:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4392:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4393:   strcpy(fileresp,"P_");
                   4394:   strcat(fileresp,fileresu);
                   4395:   /*strcat(fileresphtm,fileresu);*/
                   4396:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4397:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4398:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4399:     exit(0);
                   4400:   }
1.240     brouard  4401:   
1.226     brouard  4402:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4403:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4404:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4405:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4406:     fflush(ficlog);
                   4407:     exit(70); 
                   4408:   }
                   4409:   else{
                   4410:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4411: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4412: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4413:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4414:   }
1.237     brouard  4415:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4416:   
1.226     brouard  4417:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4418:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4419:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4420:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4421:     fflush(ficlog);
                   4422:     exit(70); 
1.240     brouard  4423:   } else{
1.226     brouard  4424:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4425: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4426: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4427:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4428:   }
1.240     brouard  4429:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4430:   
1.253     brouard  4431:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4432:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4433:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4434:   j1=0;
1.126     brouard  4435:   
1.227     brouard  4436:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4437:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4438:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4439:   
                   4440:   
1.226     brouard  4441:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4442:      reference=low_education V1=0,V2=0
                   4443:      med_educ                V1=1 V2=0, 
                   4444:      high_educ               V1=0 V2=1
                   4445:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4446:   */
1.249     brouard  4447:   dateintsum=0;
                   4448:   k2cpt=0;
                   4449: 
1.253     brouard  4450:   if(cptcoveff == 0 )
1.265     brouard  4451:     nl=1;  /* Constant and age model only */
1.253     brouard  4452:   else
                   4453:     nl=2;
1.265     brouard  4454: 
                   4455:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4456:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4457:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4458:    *     freq[s1][s2][iage] =0.
                   4459:    *     Loop on iind
                   4460:    *       ++freq[s1][s2][iage] weighted
                   4461:    *     end iind
                   4462:    *     if covariate and j!0
                   4463:    *       headers Variable on one line
                   4464:    *     endif cov j!=0
                   4465:    *     header of frequency table by age
                   4466:    *     Loop on age
                   4467:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4468:    *       pos+=freq[s1][s2][iage] weighted
                   4469:    *       Loop on s1 initial state
                   4470:    *         fprintf(ficresp
                   4471:    *       end s1
                   4472:    *     end age
                   4473:    *     if j!=0 computes starting values
                   4474:    *     end compute starting values
                   4475:    *   end j1
                   4476:    * end nl 
                   4477:    */
1.253     brouard  4478:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4479:     if(nj==1)
                   4480:       j=0;  /* First pass for the constant */
1.265     brouard  4481:     else{
1.253     brouard  4482:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4483:     }
1.251     brouard  4484:     first=1;
1.265     brouard  4485:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4486:       posproptt=0.;
                   4487:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4488:        scanf("%d", i);*/
                   4489:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4490:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4491:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4492:            freq[i][s2][m]=0;
1.251     brouard  4493:       
                   4494:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4495:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4496:          prop[i][m]=0;
                   4497:        posprop[i]=0;
                   4498:        pospropt[i]=0;
                   4499:       }
1.283     brouard  4500:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4501:         idq[z1]=0.;
                   4502:         meanq[z1]=0.;
                   4503:         stdq[z1]=0.;
1.283     brouard  4504:       }
                   4505:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4506:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4507:       /*         meanqt[m][z1]=0.; */
                   4508:       /*       } */
                   4509:       /* }       */
1.251     brouard  4510:       /* dateintsum=0; */
                   4511:       /* k2cpt=0; */
                   4512:       
1.265     brouard  4513:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4514:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4515:        bool=1;
                   4516:        if(j !=0){
                   4517:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4518:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4519:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4520:                /* if(Tvaraff[z1] ==-20){ */
                   4521:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4522:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4523:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4524:                /* }else  */
                   4525:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4526:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4527:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4528:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4529:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4530:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4531:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4532:                } /* Onlyf fixed */
                   4533:              } /* end z1 */
                   4534:            } /* cptcovn > 0 */
                   4535:          } /* end any */
                   4536:        }/* end j==0 */
1.265     brouard  4537:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4538:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4539:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4540:            m=mw[mi][iind];
                   4541:            if(j!=0){
                   4542:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4543:                for (z1=1; z1<=cptcoveff; z1++) {
                   4544:                  if( Fixed[Tmodelind[z1]]==1){
                   4545:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4546:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4547:                                                                                      value is -1, we don't select. It differs from the 
                   4548:                                                                                      constant and age model which counts them. */
                   4549:                      bool=0; /* not selected */
                   4550:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4551:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4552:                      bool=0;
                   4553:                    }
                   4554:                  }
                   4555:                }
                   4556:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4557:            } /* end j==0 */
                   4558:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4559:            if(bool==1){ /*Selected */
1.251     brouard  4560:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4561:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4562:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4563:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4564:              if(m >=firstpass && m <=lastpass){
                   4565:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4566:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4567:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4568:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4569:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4570:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4571:                if (m<lastpass) {
                   4572:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4573:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4574:                  if(s[m][iind]==-1)
                   4575:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4576:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4577:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4578:                    idq[z1]=idq[z1]+weight[iind];
                   4579:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4580:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4581:                  }
1.251     brouard  4582:                  /* if((int)agev[m][iind] == 55) */
                   4583:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4584:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4585:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4586:                }
1.251     brouard  4587:              } /* end if between passes */  
                   4588:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4589:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4590:                k2cpt++;
                   4591:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4592:              }
1.251     brouard  4593:            }else{
                   4594:              bool=1;
                   4595:            }/* end bool 2 */
                   4596:          } /* end m */
1.284     brouard  4597:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4598:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4599:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4600:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4601:          /* } */
1.251     brouard  4602:        } /* end bool */
                   4603:       } /* end iind = 1 to imx */
                   4604:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4605:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4606:       
                   4607:       
                   4608:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4609:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4610:         pstamp(ficresp);
1.251     brouard  4611:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4612:         pstamp(ficresp);
1.251     brouard  4613:        printf( "\n#********** Variable "); 
                   4614:        fprintf(ficresp, "\n#********** Variable "); 
                   4615:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4616:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4617:        fprintf(ficlog, "\n#********** Variable "); 
                   4618:        for (z1=1; z1<=cptcoveff; z1++){
                   4619:          if(!FixedV[Tvaraff[z1]]){
                   4620:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4621:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4622:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4623:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4624:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4625:          }else{
1.251     brouard  4626:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4627:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4628:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4629:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4630:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4631:          }
                   4632:        }
                   4633:        printf( "**********\n#");
                   4634:        fprintf(ficresp, "**********\n#");
                   4635:        fprintf(ficresphtm, "**********</h3>\n");
                   4636:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4637:        fprintf(ficlog, "**********\n");
                   4638:       }
1.284     brouard  4639:       /*
                   4640:        Printing means of quantitative variables if any
                   4641:       */
                   4642:       for (z1=1; z1<= nqfveff; z1++) {
1.285   ! brouard  4643:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4644:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4645:        if(weightopt==1){
                   4646:          printf(" Weighted mean and standard deviation of");
                   4647:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4648:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4649:        }
1.285   ! brouard  4650:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
        !          4651:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
        !          4652:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4653:       }
                   4654:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4655:       /*       for(m=1;m<=lastpass;m++){ */
                   4656:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4657:       /*   } */
                   4658:       /* } */
1.283     brouard  4659: 
1.251     brouard  4660:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4661:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4662:         fprintf(ficresp, " Age");
                   4663:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4664:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4665:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4666:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4667:       }
1.265     brouard  4668:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4669:       fprintf(ficresphtm, "\n");
                   4670:       
                   4671:       /* Header of frequency table by age */
                   4672:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4673:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4674:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4675:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4676:          if(s2!=0 && m!=0)
                   4677:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4678:        }
1.226     brouard  4679:       }
1.251     brouard  4680:       fprintf(ficresphtmfr, "\n");
                   4681:     
                   4682:       /* For each age */
                   4683:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4684:        fprintf(ficresphtm,"<tr>");
                   4685:        if(iage==iagemax+1){
                   4686:          fprintf(ficlog,"1");
                   4687:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4688:        }else if(iage==iagemax+2){
                   4689:          fprintf(ficlog,"0");
                   4690:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4691:        }else if(iage==iagemax+3){
                   4692:          fprintf(ficlog,"Total");
                   4693:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4694:        }else{
1.240     brouard  4695:          if(first==1){
1.251     brouard  4696:            first=0;
                   4697:            printf("See log file for details...\n");
                   4698:          }
                   4699:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4700:          fprintf(ficlog,"Age %d", iage);
                   4701:        }
1.265     brouard  4702:        for(s1=1; s1 <=nlstate ; s1++){
                   4703:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4704:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4705:        }
1.265     brouard  4706:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4707:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4708:            pos += freq[s1][m][iage];
                   4709:          if(pp[s1]>=1.e-10){
1.251     brouard  4710:            if(first==1){
1.265     brouard  4711:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4712:            }
1.265     brouard  4713:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4714:          }else{
                   4715:            if(first==1)
1.265     brouard  4716:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4717:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4718:          }
                   4719:        }
                   4720:       
1.265     brouard  4721:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4722:          /* posprop[s1]=0; */
                   4723:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4724:            pp[s1] += freq[s1][m][iage];
                   4725:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4726:       
                   4727:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4728:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4729:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4730:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4731:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4732:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4733:        }
                   4734:        
                   4735:        /* Writing ficresp */
                   4736:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4737:           if( iage <= iagemax){
                   4738:            fprintf(ficresp," %d",iage);
                   4739:           }
                   4740:         }else if( nj==2){
                   4741:           if( iage <= iagemax){
                   4742:            fprintf(ficresp," %d",iage);
                   4743:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4744:           }
1.240     brouard  4745:        }
1.265     brouard  4746:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4747:          if(pos>=1.e-5){
1.251     brouard  4748:            if(first==1)
1.265     brouard  4749:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4750:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4751:          }else{
                   4752:            if(first==1)
1.265     brouard  4753:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4754:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4755:          }
                   4756:          if( iage <= iagemax){
                   4757:            if(pos>=1.e-5){
1.265     brouard  4758:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4759:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4760:               }else if( nj==2){
                   4761:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4762:               }
                   4763:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4764:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4765:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4766:            } else{
                   4767:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4768:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4769:            }
1.240     brouard  4770:          }
1.265     brouard  4771:          pospropt[s1] +=posprop[s1];
                   4772:        } /* end loop s1 */
1.251     brouard  4773:        /* pospropt=0.; */
1.265     brouard  4774:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4775:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4776:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4777:              if(first==1){
1.265     brouard  4778:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4779:              }
1.265     brouard  4780:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4781:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4782:            }
1.265     brouard  4783:            if(s1!=0 && m!=0)
                   4784:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4785:          }
1.265     brouard  4786:        } /* end loop s1 */
1.251     brouard  4787:        posproptt=0.; 
1.265     brouard  4788:        for(s1=1; s1 <=nlstate; s1++){
                   4789:          posproptt += pospropt[s1];
1.251     brouard  4790:        }
                   4791:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4792:        fprintf(ficresphtm,"</tr>\n");
                   4793:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4794:          if(iage <= iagemax)
                   4795:            fprintf(ficresp,"\n");
1.240     brouard  4796:        }
1.251     brouard  4797:        if(first==1)
                   4798:          printf("Others in log...\n");
                   4799:        fprintf(ficlog,"\n");
                   4800:       } /* end loop age iage */
1.265     brouard  4801:       
1.251     brouard  4802:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4803:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4804:        if(posproptt < 1.e-5){
1.265     brouard  4805:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4806:        }else{
1.265     brouard  4807:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4808:        }
1.226     brouard  4809:       }
1.251     brouard  4810:       fprintf(ficresphtm,"</tr>\n");
                   4811:       fprintf(ficresphtm,"</table>\n");
                   4812:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4813:       if(posproptt < 1.e-5){
1.251     brouard  4814:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4815:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4816:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4817:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4818:        invalidvarcomb[j1]=1;
1.226     brouard  4819:       }else{
1.251     brouard  4820:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4821:        invalidvarcomb[j1]=0;
1.226     brouard  4822:       }
1.251     brouard  4823:       fprintf(ficresphtmfr,"</table>\n");
                   4824:       fprintf(ficlog,"\n");
                   4825:       if(j!=0){
                   4826:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4827:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4828:          for(k=1; k <=(nlstate+ndeath); k++){
                   4829:            if (k != i) {
1.265     brouard  4830:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4831:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4832:                  if(j1==1){ /* All dummy covariates to zero */
                   4833:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4834:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4835:                    printf("%d%d ",i,k);
                   4836:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4837:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4838:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4839:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4840:                  }
1.253     brouard  4841:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4842:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4843:                    x[iage]= (double)iage;
                   4844:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4845:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4846:                  }
1.268     brouard  4847:                  /* Some are not finite, but linreg will ignore these ages */
                   4848:                  no=0;
1.253     brouard  4849:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4850:                  pstart[s1]=b;
                   4851:                  pstart[s1-1]=a;
1.252     brouard  4852:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4853:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4854:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4855:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4856:                  printf("%d%d ",i,k);
                   4857:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4858:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4859:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4860:                  ;
                   4861:                }
                   4862:                /* printf("%12.7f )", param[i][jj][k]); */
                   4863:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4864:                s1++; 
1.251     brouard  4865:              } /* end jj */
                   4866:            } /* end k!= i */
                   4867:          } /* end k */
1.265     brouard  4868:        } /* end i, s1 */
1.251     brouard  4869:       } /* end j !=0 */
                   4870:     } /* end selected combination of covariate j1 */
                   4871:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4872:       printf("#Freqsummary: Starting values for the constants:\n");
                   4873:       fprintf(ficlog,"\n");
1.265     brouard  4874:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4875:        for(k=1; k <=(nlstate+ndeath); k++){
                   4876:          if (k != i) {
                   4877:            printf("%d%d ",i,k);
                   4878:            fprintf(ficlog,"%d%d ",i,k);
                   4879:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4880:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4881:              if(jj==1){ /* Age has to be done */
1.265     brouard  4882:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4883:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4884:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4885:              }
                   4886:              /* printf("%12.7f )", param[i][jj][k]); */
                   4887:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4888:              s1++; 
1.250     brouard  4889:            }
1.251     brouard  4890:            printf("\n");
                   4891:            fprintf(ficlog,"\n");
1.250     brouard  4892:          }
                   4893:        }
1.284     brouard  4894:       } /* end of state i */
1.251     brouard  4895:       printf("#Freqsummary\n");
                   4896:       fprintf(ficlog,"\n");
1.265     brouard  4897:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4898:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4899:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4900:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4901:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4902:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4903:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4904:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4905:          /* } */
                   4906:        }
1.265     brouard  4907:       } /* end loop s1 */
1.251     brouard  4908:       
                   4909:       printf("\n");
                   4910:       fprintf(ficlog,"\n");
                   4911:     } /* end j=0 */
1.249     brouard  4912:   } /* end j */
1.252     brouard  4913: 
1.253     brouard  4914:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4915:     for(i=1, jk=1; i <=nlstate; i++){
                   4916:       for(j=1; j <=nlstate+ndeath; j++){
                   4917:        if(j!=i){
                   4918:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4919:          printf("%1d%1d",i,j);
                   4920:          fprintf(ficparo,"%1d%1d",i,j);
                   4921:          for(k=1; k<=ncovmodel;k++){
                   4922:            /*    printf(" %lf",param[i][j][k]); */
                   4923:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4924:            p[jk]=pstart[jk];
                   4925:            printf(" %f ",pstart[jk]);
                   4926:            fprintf(ficparo," %f ",pstart[jk]);
                   4927:            jk++;
                   4928:          }
                   4929:          printf("\n");
                   4930:          fprintf(ficparo,"\n");
                   4931:        }
                   4932:       }
                   4933:     }
                   4934:   } /* end mle=-2 */
1.226     brouard  4935:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4936:   
1.226     brouard  4937:   fclose(ficresp);
                   4938:   fclose(ficresphtm);
                   4939:   fclose(ficresphtmfr);
1.283     brouard  4940:   free_vector(idq,1,nqfveff);
1.226     brouard  4941:   free_vector(meanq,1,nqfveff);
1.284     brouard  4942:   free_vector(stdq,1,nqfveff);
1.226     brouard  4943:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4944:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4945:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4946:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4947:   free_vector(pospropt,1,nlstate);
                   4948:   free_vector(posprop,1,nlstate);
1.251     brouard  4949:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4950:   free_vector(pp,1,nlstate);
                   4951:   /* End of freqsummary */
                   4952: }
1.126     brouard  4953: 
1.268     brouard  4954: /* Simple linear regression */
                   4955: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4956: 
                   4957:   /* y=a+bx regression */
                   4958:   double   sumx = 0.0;                        /* sum of x                      */
                   4959:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4960:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4961:   double   sumy = 0.0;                        /* sum of y                      */
                   4962:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4963:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4964:   double yhat;
                   4965:   
                   4966:   double denom=0;
                   4967:   int i;
                   4968:   int ne=*no;
                   4969:   
                   4970:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4971:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4972:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4973:       continue;
                   4974:     }
                   4975:     ne=ne+1;
                   4976:     sumx  += x[i];       
                   4977:     sumx2 += x[i]*x[i];  
                   4978:     sumxy += x[i] * y[i];
                   4979:     sumy  += y[i];      
                   4980:     sumy2 += y[i]*y[i]; 
                   4981:     denom = (ne * sumx2 - sumx*sumx);
                   4982:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4983:   } 
                   4984:   
                   4985:   denom = (ne * sumx2 - sumx*sumx);
                   4986:   if (denom == 0) {
                   4987:     // vertical, slope m is infinity
                   4988:     *b = INFINITY;
                   4989:     *a = 0;
                   4990:     if (r) *r = 0;
                   4991:     return 1;
                   4992:   }
                   4993:   
                   4994:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4995:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4996:   if (r!=NULL) {
                   4997:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4998:       sqrt((sumx2 - sumx*sumx/ne) *
                   4999:           (sumy2 - sumy*sumy/ne));
                   5000:   }
                   5001:   *no=ne;
                   5002:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5003:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5004:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5005:       continue;
                   5006:     }
                   5007:     ne=ne+1;
                   5008:     yhat = y[i] - *a -*b* x[i];
                   5009:     sume2  += yhat * yhat ;       
                   5010:     
                   5011:     denom = (ne * sumx2 - sumx*sumx);
                   5012:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5013:   } 
                   5014:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5015:   *sa= *sb * sqrt(sumx2/ne);
                   5016:   
                   5017:   return 0; 
                   5018: }
                   5019: 
1.126     brouard  5020: /************ Prevalence ********************/
1.227     brouard  5021: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5022: {  
                   5023:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5024:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5025:      We still use firstpass and lastpass as another selection.
                   5026:   */
1.126     brouard  5027:  
1.227     brouard  5028:   int i, m, jk, j1, bool, z1,j, iv;
                   5029:   int mi; /* Effective wave */
                   5030:   int iage;
                   5031:   double agebegin, ageend;
                   5032: 
                   5033:   double **prop;
                   5034:   double posprop; 
                   5035:   double  y2; /* in fractional years */
                   5036:   int iagemin, iagemax;
                   5037:   int first; /** to stop verbosity which is redirected to log file */
                   5038: 
                   5039:   iagemin= (int) agemin;
                   5040:   iagemax= (int) agemax;
                   5041:   /*pp=vector(1,nlstate);*/
1.251     brouard  5042:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5043:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5044:   j1=0;
1.222     brouard  5045:   
1.227     brouard  5046:   /*j=cptcoveff;*/
                   5047:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5048:   
1.227     brouard  5049:   first=1;
                   5050:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5051:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5052:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5053:        prop[i][iage]=0.0;
                   5054:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5055:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5056:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5057:     
                   5058:     for (i=1; i<=imx; i++) { /* Each individual */
                   5059:       bool=1;
                   5060:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5061:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5062:        m=mw[mi][i];
                   5063:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5064:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5065:        for (z1=1; z1<=cptcoveff; z1++){
                   5066:          if( Fixed[Tmodelind[z1]]==1){
                   5067:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5068:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5069:              bool=0;
                   5070:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5071:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5072:              bool=0;
                   5073:            }
                   5074:        }
                   5075:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5076:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5077:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5078:          if(m >=firstpass && m <=lastpass){
                   5079:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5080:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5081:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5082:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5083:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5084:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5085:                exit(1);
                   5086:              }
                   5087:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5088:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5089:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5090:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5091:              } /* end valid statuses */ 
                   5092:            } /* end selection of dates */
                   5093:          } /* end selection of waves */
                   5094:        } /* end bool */
                   5095:       } /* end wave */
                   5096:     } /* end individual */
                   5097:     for(i=iagemin; i <= iagemax+3; i++){  
                   5098:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5099:        posprop += prop[jk][i]; 
                   5100:       } 
                   5101:       
                   5102:       for(jk=1; jk <=nlstate ; jk++){      
                   5103:        if( i <=  iagemax){ 
                   5104:          if(posprop>=1.e-5){ 
                   5105:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5106:          } else{
                   5107:            if(first==1){
                   5108:              first=0;
1.266     brouard  5109:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5110:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5111:            }else{
                   5112:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5113:            }
                   5114:          }
                   5115:        } 
                   5116:       }/* end jk */ 
                   5117:     }/* end i */ 
1.222     brouard  5118:      /*} *//* end i1 */
1.227     brouard  5119:   } /* end j1 */
1.222     brouard  5120:   
1.227     brouard  5121:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5122:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5123:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5124: }  /* End of prevalence */
1.126     brouard  5125: 
                   5126: /************* Waves Concatenation ***************/
                   5127: 
                   5128: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5129: {
                   5130:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5131:      Death is a valid wave (if date is known).
                   5132:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5133:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5134:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5135:   */
1.126     brouard  5136: 
1.224     brouard  5137:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5138:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5139:      double sum=0., jmean=0.;*/
1.224     brouard  5140:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5141:   int j, k=0,jk, ju, jl;
                   5142:   double sum=0.;
                   5143:   first=0;
1.214     brouard  5144:   firstwo=0;
1.217     brouard  5145:   firsthree=0;
1.218     brouard  5146:   firstfour=0;
1.164     brouard  5147:   jmin=100000;
1.126     brouard  5148:   jmax=-1;
                   5149:   jmean=0.;
1.224     brouard  5150: 
                   5151: /* Treating live states */
1.214     brouard  5152:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5153:     mi=0;  /* First valid wave */
1.227     brouard  5154:     mli=0; /* Last valid wave */
1.126     brouard  5155:     m=firstpass;
1.214     brouard  5156:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5157:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5158:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5159:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5160:        mw[++mi][i]=m;
                   5161:        mli=m;
1.224     brouard  5162:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5163:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5164:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5165:       }
1.227     brouard  5166:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5167: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5168:        break;
1.224     brouard  5169: #else
1.227     brouard  5170:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5171:          if(firsthree == 0){
1.262     brouard  5172:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5173:            firsthree=1;
                   5174:          }
1.262     brouard  5175:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5176:          mw[++mi][i]=m;
                   5177:          mli=m;
                   5178:        }
                   5179:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5180:          nbwarn++;
                   5181:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5182:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5183:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5184:          }
                   5185:          break;
                   5186:        }
                   5187:        break;
1.224     brouard  5188: #endif
1.227     brouard  5189:       }/* End m >= lastpass */
1.126     brouard  5190:     }/* end while */
1.224     brouard  5191: 
1.227     brouard  5192:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5193:     /* After last pass */
1.224     brouard  5194: /* Treating death states */
1.214     brouard  5195:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5196:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5197:       /* } */
1.126     brouard  5198:       mi++;    /* Death is another wave */
                   5199:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5200:       /* Only death is a correct wave */
1.126     brouard  5201:       mw[mi][i]=m;
1.257     brouard  5202:     } /* else not in a death state */
1.224     brouard  5203: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5204:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5205:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5206:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5207:          nbwarn++;
                   5208:          if(firstfiv==0){
                   5209:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5210:            firstfiv=1;
                   5211:          }else{
                   5212:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5213:          }
                   5214:        }else{ /* Death occured afer last wave potential bias */
                   5215:          nberr++;
                   5216:          if(firstwo==0){
1.257     brouard  5217:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5218:            firstwo=1;
                   5219:          }
1.257     brouard  5220:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5221:        }
1.257     brouard  5222:       }else{ /* if date of interview is unknown */
1.227     brouard  5223:        /* death is known but not confirmed by death status at any wave */
                   5224:        if(firstfour==0){
                   5225:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5226:          firstfour=1;
                   5227:        }
                   5228:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5229:       }
1.224     brouard  5230:     } /* end if date of death is known */
                   5231: #endif
                   5232:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5233:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5234:     if(mi==0){
                   5235:       nbwarn++;
                   5236:       if(first==0){
1.227     brouard  5237:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5238:        first=1;
1.126     brouard  5239:       }
                   5240:       if(first==1){
1.227     brouard  5241:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5242:       }
                   5243:     } /* end mi==0 */
                   5244:   } /* End individuals */
1.214     brouard  5245:   /* wav and mw are no more changed */
1.223     brouard  5246:        
1.214     brouard  5247:   
1.126     brouard  5248:   for(i=1; i<=imx; i++){
                   5249:     for(mi=1; mi<wav[i];mi++){
                   5250:       if (stepm <=0)
1.227     brouard  5251:        dh[mi][i]=1;
1.126     brouard  5252:       else{
1.260     brouard  5253:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5254:          if (agedc[i] < 2*AGESUP) {
                   5255:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5256:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5257:            else if(j<0){
                   5258:              nberr++;
                   5259:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5260:              j=1; /* Temporary Dangerous patch */
                   5261:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5262:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5263:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5264:            }
                   5265:            k=k+1;
                   5266:            if (j >= jmax){
                   5267:              jmax=j;
                   5268:              ijmax=i;
                   5269:            }
                   5270:            if (j <= jmin){
                   5271:              jmin=j;
                   5272:              ijmin=i;
                   5273:            }
                   5274:            sum=sum+j;
                   5275:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5276:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5277:          }
                   5278:        }
                   5279:        else{
                   5280:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5281: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5282:                                        
1.227     brouard  5283:          k=k+1;
                   5284:          if (j >= jmax) {
                   5285:            jmax=j;
                   5286:            ijmax=i;
                   5287:          }
                   5288:          else if (j <= jmin){
                   5289:            jmin=j;
                   5290:            ijmin=i;
                   5291:          }
                   5292:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5293:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5294:          if(j<0){
                   5295:            nberr++;
                   5296:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5297:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5298:          }
                   5299:          sum=sum+j;
                   5300:        }
                   5301:        jk= j/stepm;
                   5302:        jl= j -jk*stepm;
                   5303:        ju= j -(jk+1)*stepm;
                   5304:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5305:          if(jl==0){
                   5306:            dh[mi][i]=jk;
                   5307:            bh[mi][i]=0;
                   5308:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5309:                  * to avoid the price of an extra matrix product in likelihood */
                   5310:            dh[mi][i]=jk+1;
                   5311:            bh[mi][i]=ju;
                   5312:          }
                   5313:        }else{
                   5314:          if(jl <= -ju){
                   5315:            dh[mi][i]=jk;
                   5316:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5317:                                 * is higher than the multiple of stepm and negative otherwise.
                   5318:                                 */
                   5319:          }
                   5320:          else{
                   5321:            dh[mi][i]=jk+1;
                   5322:            bh[mi][i]=ju;
                   5323:          }
                   5324:          if(dh[mi][i]==0){
                   5325:            dh[mi][i]=1; /* At least one step */
                   5326:            bh[mi][i]=ju; /* At least one step */
                   5327:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5328:          }
                   5329:        } /* end if mle */
1.126     brouard  5330:       }
                   5331:     } /* end wave */
                   5332:   }
                   5333:   jmean=sum/k;
                   5334:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5335:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5336: }
1.126     brouard  5337: 
                   5338: /*********** Tricode ****************************/
1.220     brouard  5339:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5340:  {
                   5341:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5342:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5343:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5344:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5345:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5346:     */
1.130     brouard  5347: 
1.242     brouard  5348:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5349:    int modmaxcovj=0; /* Modality max of covariates j */
                   5350:    int cptcode=0; /* Modality max of covariates j */
                   5351:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5352: 
                   5353: 
1.242     brouard  5354:    /* cptcoveff=0;  */
                   5355:    /* *cptcov=0; */
1.126     brouard  5356:  
1.242     brouard  5357:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285   ! brouard  5358:    for (k=1; k <= maxncov; k++)
        !          5359:      for(j=1; j<=2; j++)
        !          5360:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5361: 
1.242     brouard  5362:    /* Loop on covariates without age and products and no quantitative variable */
                   5363:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5364:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5365:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5366:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5367:        switch(Fixed[k]) {
                   5368:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5369:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5370:           ij=(int)(covar[Tvar[k]][i]);
                   5371:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5372:            * If product of Vn*Vm, still boolean *:
                   5373:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5374:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5375:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5376:              modality of the nth covariate of individual i. */
                   5377:           if (ij > modmaxcovj)
                   5378:             modmaxcovj=ij; 
                   5379:           else if (ij < modmincovj) 
                   5380:             modmincovj=ij; 
                   5381:           if ((ij < -1) && (ij > NCOVMAX)){
                   5382:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5383:             exit(1);
                   5384:           }else
                   5385:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5386:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5387:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5388:           /* getting the maximum value of the modality of the covariate
                   5389:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5390:              female ies 1, then modmaxcovj=1.
                   5391:           */
                   5392:         } /* end for loop on individuals i */
                   5393:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5394:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5395:         cptcode=modmaxcovj;
                   5396:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5397:         /*for (i=0; i<=cptcode; i++) {*/
                   5398:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5399:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5400:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5401:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5402:             if( j != -1){
                   5403:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5404:                                  covariate for which somebody answered excluding 
                   5405:                                  undefined. Usually 2: 0 and 1. */
                   5406:             }
                   5407:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5408:                                     covariate for which somebody answered including 
                   5409:                                     undefined. Usually 3: -1, 0 and 1. */
                   5410:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5411:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5412:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5413:                        
1.242     brouard  5414:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5415:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5416:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5417:         /* modmincovj=3; modmaxcovj = 7; */
                   5418:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5419:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5420:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5421:         /* nbcode[Tvar[j]][ij]=k; */
                   5422:         /* nbcode[Tvar[j]][1]=0; */
                   5423:         /* nbcode[Tvar[j]][2]=1; */
                   5424:         /* nbcode[Tvar[j]][3]=2; */
                   5425:         /* To be continued (not working yet). */
                   5426:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5427:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5428:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5429:             break;
                   5430:           }
                   5431:           ij++;
                   5432:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5433:           cptcode = ij; /* New max modality for covar j */
                   5434:         } /* end of loop on modality i=-1 to 1 or more */
                   5435:         break;
                   5436:        case 1: /* Testing on varying covariate, could be simple and
                   5437:                * should look at waves or product of fixed *
                   5438:                * varying. No time to test -1, assuming 0 and 1 only */
                   5439:         ij=0;
                   5440:         for(i=0; i<=1;i++){
                   5441:           nbcode[Tvar[k]][++ij]=i;
                   5442:         }
                   5443:         break;
                   5444:        default:
                   5445:         break;
                   5446:        } /* end switch */
                   5447:      } /* end dummy test */
                   5448:     
                   5449:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5450:      /*        /\*recode from 0 *\/ */
                   5451:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5452:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5453:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5454:      /*        } */
                   5455:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5456:      /*        if (ij > ncodemax[j]) { */
                   5457:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5458:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5459:      /*          break; */
                   5460:      /*        } */
                   5461:      /*   }  /\* end of loop on modality k *\/ */
                   5462:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5463:   
                   5464:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5465:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5466:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5467:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5468:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5469:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5470:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5471:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5472:   
                   5473:    ij=0;
                   5474:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5475:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5476:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5477:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5478:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5479:        /* If product not in single variable we don't print results */
                   5480:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5481:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5482:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5483:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5484:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5485:        if(Fixed[k]!=0)
                   5486:         anyvaryingduminmodel=1;
                   5487:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5488:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5489:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5490:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5491:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5492:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5493:      } 
                   5494:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5495:    /* ij--; */
                   5496:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5497:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5498:                * because they can be excluded from the model and real
                   5499:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5500:    for(j=ij+1; j<= cptcovt; j++){
                   5501:      Tvaraff[j]=0;
                   5502:      Tmodelind[j]=0;
                   5503:    }
                   5504:    for(j=ntveff+1; j<= cptcovt; j++){
                   5505:      TmodelInvind[j]=0;
                   5506:    }
                   5507:    /* To be sorted */
                   5508:    ;
                   5509:  }
1.126     brouard  5510: 
1.145     brouard  5511: 
1.126     brouard  5512: /*********** Health Expectancies ****************/
                   5513: 
1.235     brouard  5514:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5515: 
                   5516: {
                   5517:   /* Health expectancies, no variances */
1.164     brouard  5518:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5519:   int nhstepma, nstepma; /* Decreasing with age */
                   5520:   double age, agelim, hf;
                   5521:   double ***p3mat;
                   5522:   double eip;
                   5523: 
1.238     brouard  5524:   /* pstamp(ficreseij); */
1.126     brouard  5525:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5526:   fprintf(ficreseij,"# Age");
                   5527:   for(i=1; i<=nlstate;i++){
                   5528:     for(j=1; j<=nlstate;j++){
                   5529:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5530:     }
                   5531:     fprintf(ficreseij," e%1d. ",i);
                   5532:   }
                   5533:   fprintf(ficreseij,"\n");
                   5534: 
                   5535:   
                   5536:   if(estepm < stepm){
                   5537:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5538:   }
                   5539:   else  hstepm=estepm;   
                   5540:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5541:    * This is mainly to measure the difference between two models: for example
                   5542:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5543:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5544:    * progression in between and thus overestimating or underestimating according
                   5545:    * to the curvature of the survival function. If, for the same date, we 
                   5546:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5547:    * to compare the new estimate of Life expectancy with the same linear 
                   5548:    * hypothesis. A more precise result, taking into account a more precise
                   5549:    * curvature will be obtained if estepm is as small as stepm. */
                   5550: 
                   5551:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5552:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5553:      nhstepm is the number of hstepm from age to agelim 
                   5554:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5555:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5556:      and note for a fixed period like estepm months */
                   5557:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5558:      survival function given by stepm (the optimization length). Unfortunately it
                   5559:      means that if the survival funtion is printed only each two years of age and if
                   5560:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5561:      results. So we changed our mind and took the option of the best precision.
                   5562:   */
                   5563:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5564: 
                   5565:   agelim=AGESUP;
                   5566:   /* If stepm=6 months */
                   5567:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5568:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5569:     
                   5570: /* nhstepm age range expressed in number of stepm */
                   5571:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5572:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5573:   /* if (stepm >= YEARM) hstepm=1;*/
                   5574:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5575:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5576: 
                   5577:   for (age=bage; age<=fage; age ++){ 
                   5578:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5579:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5580:     /* if (stepm >= YEARM) hstepm=1;*/
                   5581:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5582: 
                   5583:     /* If stepm=6 months */
                   5584:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5585:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5586:     
1.235     brouard  5587:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5588:     
                   5589:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5590:     
                   5591:     printf("%d|",(int)age);fflush(stdout);
                   5592:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5593:     
                   5594:     /* Computing expectancies */
                   5595:     for(i=1; i<=nlstate;i++)
                   5596:       for(j=1; j<=nlstate;j++)
                   5597:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5598:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5599:          
                   5600:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5601: 
                   5602:        }
                   5603: 
                   5604:     fprintf(ficreseij,"%3.0f",age );
                   5605:     for(i=1; i<=nlstate;i++){
                   5606:       eip=0;
                   5607:       for(j=1; j<=nlstate;j++){
                   5608:        eip +=eij[i][j][(int)age];
                   5609:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5610:       }
                   5611:       fprintf(ficreseij,"%9.4f", eip );
                   5612:     }
                   5613:     fprintf(ficreseij,"\n");
                   5614:     
                   5615:   }
                   5616:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5617:   printf("\n");
                   5618:   fprintf(ficlog,"\n");
                   5619:   
                   5620: }
                   5621: 
1.235     brouard  5622:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5623: 
                   5624: {
                   5625:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5626:      to initial status i, ei. .
1.126     brouard  5627:   */
                   5628:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5629:   int nhstepma, nstepma; /* Decreasing with age */
                   5630:   double age, agelim, hf;
                   5631:   double ***p3matp, ***p3matm, ***varhe;
                   5632:   double **dnewm,**doldm;
                   5633:   double *xp, *xm;
                   5634:   double **gp, **gm;
                   5635:   double ***gradg, ***trgradg;
                   5636:   int theta;
                   5637: 
                   5638:   double eip, vip;
                   5639: 
                   5640:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5641:   xp=vector(1,npar);
                   5642:   xm=vector(1,npar);
                   5643:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5644:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5645:   
                   5646:   pstamp(ficresstdeij);
                   5647:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5648:   fprintf(ficresstdeij,"# Age");
                   5649:   for(i=1; i<=nlstate;i++){
                   5650:     for(j=1; j<=nlstate;j++)
                   5651:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5652:     fprintf(ficresstdeij," e%1d. ",i);
                   5653:   }
                   5654:   fprintf(ficresstdeij,"\n");
                   5655: 
                   5656:   pstamp(ficrescveij);
                   5657:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5658:   fprintf(ficrescveij,"# Age");
                   5659:   for(i=1; i<=nlstate;i++)
                   5660:     for(j=1; j<=nlstate;j++){
                   5661:       cptj= (j-1)*nlstate+i;
                   5662:       for(i2=1; i2<=nlstate;i2++)
                   5663:        for(j2=1; j2<=nlstate;j2++){
                   5664:          cptj2= (j2-1)*nlstate+i2;
                   5665:          if(cptj2 <= cptj)
                   5666:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5667:        }
                   5668:     }
                   5669:   fprintf(ficrescveij,"\n");
                   5670:   
                   5671:   if(estepm < stepm){
                   5672:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5673:   }
                   5674:   else  hstepm=estepm;   
                   5675:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5676:    * This is mainly to measure the difference between two models: for example
                   5677:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5678:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5679:    * progression in between and thus overestimating or underestimating according
                   5680:    * to the curvature of the survival function. If, for the same date, we 
                   5681:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5682:    * to compare the new estimate of Life expectancy with the same linear 
                   5683:    * hypothesis. A more precise result, taking into account a more precise
                   5684:    * curvature will be obtained if estepm is as small as stepm. */
                   5685: 
                   5686:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5687:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5688:      nhstepm is the number of hstepm from age to agelim 
                   5689:      nstepm is the number of stepm from age to agelin. 
                   5690:      Look at hpijx to understand the reason of that which relies in memory size
                   5691:      and note for a fixed period like estepm months */
                   5692:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5693:      survival function given by stepm (the optimization length). Unfortunately it
                   5694:      means that if the survival funtion is printed only each two years of age and if
                   5695:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5696:      results. So we changed our mind and took the option of the best precision.
                   5697:   */
                   5698:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5699: 
                   5700:   /* If stepm=6 months */
                   5701:   /* nhstepm age range expressed in number of stepm */
                   5702:   agelim=AGESUP;
                   5703:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5704:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5705:   /* if (stepm >= YEARM) hstepm=1;*/
                   5706:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5707:   
                   5708:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5709:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5710:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5711:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5712:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5713:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5714: 
                   5715:   for (age=bage; age<=fage; age ++){ 
                   5716:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5717:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5718:     /* if (stepm >= YEARM) hstepm=1;*/
                   5719:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5720:                
1.126     brouard  5721:     /* If stepm=6 months */
                   5722:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5723:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5724:     
                   5725:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5726:                
1.126     brouard  5727:     /* Computing  Variances of health expectancies */
                   5728:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5729:        decrease memory allocation */
                   5730:     for(theta=1; theta <=npar; theta++){
                   5731:       for(i=1; i<=npar; i++){ 
1.222     brouard  5732:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5733:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5734:       }
1.235     brouard  5735:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5736:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5737:                        
1.126     brouard  5738:       for(j=1; j<= nlstate; j++){
1.222     brouard  5739:        for(i=1; i<=nlstate; i++){
                   5740:          for(h=0; h<=nhstepm-1; h++){
                   5741:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5742:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5743:          }
                   5744:        }
1.126     brouard  5745:       }
1.218     brouard  5746:                        
1.126     brouard  5747:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5748:        for(h=0; h<=nhstepm-1; h++){
                   5749:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5750:        }
1.126     brouard  5751:     }/* End theta */
                   5752:     
                   5753:     
                   5754:     for(h=0; h<=nhstepm-1; h++)
                   5755:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5756:        for(theta=1; theta <=npar; theta++)
                   5757:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5758:     
1.218     brouard  5759:                
1.222     brouard  5760:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5761:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5762:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5763:                
1.222     brouard  5764:     printf("%d|",(int)age);fflush(stdout);
                   5765:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5766:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5767:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5768:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5769:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5770:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5771:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5772:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5773:       }
                   5774:     }
1.218     brouard  5775:                
1.126     brouard  5776:     /* Computing expectancies */
1.235     brouard  5777:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5778:     for(i=1; i<=nlstate;i++)
                   5779:       for(j=1; j<=nlstate;j++)
1.222     brouard  5780:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5781:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5782:                                        
1.222     brouard  5783:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5784:                                        
1.222     brouard  5785:        }
1.269     brouard  5786: 
                   5787:     /* Standard deviation of expectancies ij */                
1.126     brouard  5788:     fprintf(ficresstdeij,"%3.0f",age );
                   5789:     for(i=1; i<=nlstate;i++){
                   5790:       eip=0.;
                   5791:       vip=0.;
                   5792:       for(j=1; j<=nlstate;j++){
1.222     brouard  5793:        eip += eij[i][j][(int)age];
                   5794:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5795:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5796:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5797:       }
                   5798:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5799:     }
                   5800:     fprintf(ficresstdeij,"\n");
1.218     brouard  5801:                
1.269     brouard  5802:     /* Variance of expectancies ij */          
1.126     brouard  5803:     fprintf(ficrescveij,"%3.0f",age );
                   5804:     for(i=1; i<=nlstate;i++)
                   5805:       for(j=1; j<=nlstate;j++){
1.222     brouard  5806:        cptj= (j-1)*nlstate+i;
                   5807:        for(i2=1; i2<=nlstate;i2++)
                   5808:          for(j2=1; j2<=nlstate;j2++){
                   5809:            cptj2= (j2-1)*nlstate+i2;
                   5810:            if(cptj2 <= cptj)
                   5811:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5812:          }
1.126     brouard  5813:       }
                   5814:     fprintf(ficrescveij,"\n");
1.218     brouard  5815:                
1.126     brouard  5816:   }
                   5817:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5818:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5819:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5820:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5821:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5822:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5823:   printf("\n");
                   5824:   fprintf(ficlog,"\n");
1.218     brouard  5825:        
1.126     brouard  5826:   free_vector(xm,1,npar);
                   5827:   free_vector(xp,1,npar);
                   5828:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5829:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5830:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5831: }
1.218     brouard  5832:  
1.126     brouard  5833: /************ Variance ******************/
1.235     brouard  5834:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5835:  {
1.279     brouard  5836:    /** Variance of health expectancies 
                   5837:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5838:     * double **newm;
                   5839:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5840:     */
1.218     brouard  5841:   
                   5842:    /* int movingaverage(); */
                   5843:    double **dnewm,**doldm;
                   5844:    double **dnewmp,**doldmp;
                   5845:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5846:    int k;
                   5847:    double *xp;
1.279     brouard  5848:    double **gp, **gm;  /**< for var eij */
                   5849:    double ***gradg, ***trgradg; /**< for var eij */
                   5850:    double **gradgp, **trgradgp; /**< for var p point j */
                   5851:    double *gpp, *gmp; /**< for var p point j */
                   5852:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5853:    double ***p3mat;
                   5854:    double age,agelim, hf;
                   5855:    /* double ***mobaverage; */
                   5856:    int theta;
                   5857:    char digit[4];
                   5858:    char digitp[25];
                   5859: 
                   5860:    char fileresprobmorprev[FILENAMELENGTH];
                   5861: 
                   5862:    if(popbased==1){
                   5863:      if(mobilav!=0)
                   5864:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5865:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5866:    }
                   5867:    else 
                   5868:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5869: 
1.218     brouard  5870:    /* if (mobilav!=0) { */
                   5871:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5872:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5873:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5874:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5875:    /*   } */
                   5876:    /* } */
                   5877: 
                   5878:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5879:    sprintf(digit,"%-d",ij);
                   5880:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5881:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5882:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5883:    strcat(fileresprobmorprev,fileresu);
                   5884:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5885:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5886:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5887:    }
                   5888:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5889:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5890:    pstamp(ficresprobmorprev);
                   5891:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5892:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5893:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5894:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5895:    }
                   5896:    for(j=1;j<=cptcoveff;j++) 
                   5897:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5898:    fprintf(ficresprobmorprev,"\n");
                   5899: 
1.218     brouard  5900:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5901:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5902:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5903:      for(i=1; i<=nlstate;i++)
                   5904:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5905:    }  
                   5906:    fprintf(ficresprobmorprev,"\n");
                   5907:   
                   5908:    fprintf(ficgp,"\n# Routine varevsij");
                   5909:    fprintf(ficgp,"\nunset title \n");
                   5910:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5911:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5912:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5913: 
1.218     brouard  5914:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5915:    pstamp(ficresvij);
                   5916:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5917:    if(popbased==1)
                   5918:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5919:    else
                   5920:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5921:    fprintf(ficresvij,"# Age");
                   5922:    for(i=1; i<=nlstate;i++)
                   5923:      for(j=1; j<=nlstate;j++)
                   5924:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5925:    fprintf(ficresvij,"\n");
                   5926: 
                   5927:    xp=vector(1,npar);
                   5928:    dnewm=matrix(1,nlstate,1,npar);
                   5929:    doldm=matrix(1,nlstate,1,nlstate);
                   5930:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5931:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5932: 
                   5933:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5934:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5935:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5936:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5937:   
1.218     brouard  5938:    if(estepm < stepm){
                   5939:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5940:    }
                   5941:    else  hstepm=estepm;   
                   5942:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5943:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5944:       nhstepm is the number of hstepm from age to agelim 
                   5945:       nstepm is the number of stepm from age to agelim. 
                   5946:       Look at function hpijx to understand why because of memory size limitations, 
                   5947:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5948:       survival function given by stepm (the optimization length). Unfortunately it
                   5949:       means that if the survival funtion is printed every two years of age and if
                   5950:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5951:       results. So we changed our mind and took the option of the best precision.
                   5952:    */
                   5953:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5954:    agelim = AGESUP;
                   5955:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5956:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5957:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5958:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5959:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5960:      gp=matrix(0,nhstepm,1,nlstate);
                   5961:      gm=matrix(0,nhstepm,1,nlstate);
                   5962:                
                   5963:                
                   5964:      for(theta=1; theta <=npar; theta++){
                   5965:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5966:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5967:        }
1.279     brouard  5968:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5969:        * returns into prlim .
                   5970:        */              
1.242     brouard  5971:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5972: 
                   5973:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5974:        if (popbased==1) {
                   5975:         if(mobilav ==0){
                   5976:           for(i=1; i<=nlstate;i++)
                   5977:             prlim[i][i]=probs[(int)age][i][ij];
                   5978:         }else{ /* mobilav */ 
                   5979:           for(i=1; i<=nlstate;i++)
                   5980:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5981:         }
                   5982:        }
1.279     brouard  5983:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5984:        */                      
                   5985:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   5986:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   5987:        * at horizon h in state j including mortality.
                   5988:        */
1.218     brouard  5989:        for(j=1; j<= nlstate; j++){
                   5990:         for(h=0; h<=nhstepm; h++){
                   5991:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5992:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5993:         }
                   5994:        }
1.279     brouard  5995:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  5996:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  5997:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  5998:        */
                   5999:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6000:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6001:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6002:        }
                   6003:        
                   6004:        /* Again with minus shift */
1.218     brouard  6005:                        
                   6006:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6007:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6008:                        
1.242     brouard  6009:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6010:                        
                   6011:        if (popbased==1) {
                   6012:         if(mobilav ==0){
                   6013:           for(i=1; i<=nlstate;i++)
                   6014:             prlim[i][i]=probs[(int)age][i][ij];
                   6015:         }else{ /* mobilav */ 
                   6016:           for(i=1; i<=nlstate;i++)
                   6017:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6018:         }
                   6019:        }
                   6020:                        
1.235     brouard  6021:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6022:                        
                   6023:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6024:         for(h=0; h<=nhstepm; h++){
                   6025:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6026:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6027:         }
                   6028:        }
                   6029:        /* This for computing probability of death (h=1 means
                   6030:          computed over hstepm matrices product = hstepm*stepm months) 
                   6031:          as a weighted average of prlim.
                   6032:        */
                   6033:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6034:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6035:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6036:        }    
1.279     brouard  6037:        /* end shifting computations */
                   6038: 
                   6039:        /**< Computing gradient matrix at horizon h 
                   6040:        */
1.218     brouard  6041:        for(j=1; j<= nlstate; j++) /* vareij */
                   6042:         for(h=0; h<=nhstepm; h++){
                   6043:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6044:         }
1.279     brouard  6045:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6046:        */
                   6047:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6048:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6049:        }
                   6050:                        
                   6051:      } /* End theta */
1.279     brouard  6052:      
                   6053:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6054:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6055:                
                   6056:      for(h=0; h<=nhstepm; h++) /* veij */
                   6057:        for(j=1; j<=nlstate;j++)
                   6058:         for(theta=1; theta <=npar; theta++)
                   6059:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6060:                
                   6061:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6062:        for(theta=1; theta <=npar; theta++)
                   6063:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6064:      /**< as well as its transposed matrix 
                   6065:       */               
1.218     brouard  6066:                
                   6067:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6068:      for(i=1;i<=nlstate;i++)
                   6069:        for(j=1;j<=nlstate;j++)
                   6070:         vareij[i][j][(int)age] =0.;
1.279     brouard  6071: 
                   6072:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6073:       * and k (nhstepm) formula 15 of article
                   6074:       * Lievre-Brouard-Heathcote
                   6075:       */
                   6076:      
1.218     brouard  6077:      for(h=0;h<=nhstepm;h++){
                   6078:        for(k=0;k<=nhstepm;k++){
                   6079:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6080:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6081:         for(i=1;i<=nlstate;i++)
                   6082:           for(j=1;j<=nlstate;j++)
                   6083:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6084:        }
                   6085:      }
                   6086:                
1.279     brouard  6087:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6088:       * p.j overall mortality formula 49 but computed directly because
                   6089:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6090:       * wix is independent of theta.
                   6091:       */
1.218     brouard  6092:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6093:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6094:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6095:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6096:         varppt[j][i]=doldmp[j][i];
                   6097:      /* end ppptj */
                   6098:      /*  x centered again */
                   6099:                
1.242     brouard  6100:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6101:                
                   6102:      if (popbased==1) {
                   6103:        if(mobilav ==0){
                   6104:         for(i=1; i<=nlstate;i++)
                   6105:           prlim[i][i]=probs[(int)age][i][ij];
                   6106:        }else{ /* mobilav */ 
                   6107:         for(i=1; i<=nlstate;i++)
                   6108:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6109:        }
                   6110:      }
                   6111:                
                   6112:      /* This for computing probability of death (h=1 means
                   6113:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6114:        as a weighted average of prlim.
                   6115:      */
1.235     brouard  6116:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6117:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6118:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6119:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6120:      }    
                   6121:      /* end probability of death */
                   6122:                
                   6123:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6124:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6125:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6126:        for(i=1; i<=nlstate;i++){
                   6127:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6128:        }
                   6129:      } 
                   6130:      fprintf(ficresprobmorprev,"\n");
                   6131:                
                   6132:      fprintf(ficresvij,"%.0f ",age );
                   6133:      for(i=1; i<=nlstate;i++)
                   6134:        for(j=1; j<=nlstate;j++){
                   6135:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6136:        }
                   6137:      fprintf(ficresvij,"\n");
                   6138:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6139:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6140:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6141:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6142:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6143:    } /* End age */
                   6144:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6145:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6146:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6147:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6148:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6149:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6150:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6151:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6152:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6153:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6154:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6155:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6156:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6157:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6158:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6159:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6160:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6161:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6162:     */
1.218     brouard  6163:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6164:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6165: 
1.218     brouard  6166:    free_vector(xp,1,npar);
                   6167:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6168:    free_matrix(dnewm,1,nlstate,1,npar);
                   6169:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6170:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6171:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6172:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6173:    fclose(ficresprobmorprev);
                   6174:    fflush(ficgp);
                   6175:    fflush(fichtm); 
                   6176:  }  /* end varevsij */
1.126     brouard  6177: 
                   6178: /************ Variance of prevlim ******************/
1.269     brouard  6179:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6180: {
1.205     brouard  6181:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6182:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6183: 
1.268     brouard  6184:   double **dnewmpar,**doldm;
1.126     brouard  6185:   int i, j, nhstepm, hstepm;
                   6186:   double *xp;
                   6187:   double *gp, *gm;
                   6188:   double **gradg, **trgradg;
1.208     brouard  6189:   double **mgm, **mgp;
1.126     brouard  6190:   double age,agelim;
                   6191:   int theta;
                   6192:   
                   6193:   pstamp(ficresvpl);
                   6194:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6195:   fprintf(ficresvpl,"# Age ");
                   6196:   if(nresult >=1)
                   6197:     fprintf(ficresvpl," Result# ");
1.126     brouard  6198:   for(i=1; i<=nlstate;i++)
                   6199:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6200:   fprintf(ficresvpl,"\n");
                   6201: 
                   6202:   xp=vector(1,npar);
1.268     brouard  6203:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6204:   doldm=matrix(1,nlstate,1,nlstate);
                   6205:   
                   6206:   hstepm=1*YEARM; /* Every year of age */
                   6207:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6208:   agelim = AGESUP;
                   6209:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6210:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6211:     if (stepm >= YEARM) hstepm=1;
                   6212:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6213:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6214:     mgp=matrix(1,npar,1,nlstate);
                   6215:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6216:     gp=vector(1,nlstate);
                   6217:     gm=vector(1,nlstate);
                   6218: 
                   6219:     for(theta=1; theta <=npar; theta++){
                   6220:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6221:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6222:       }
1.209     brouard  6223:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6224:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6225:       else
1.235     brouard  6226:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6227:       for(i=1;i<=nlstate;i++){
1.126     brouard  6228:        gp[i] = prlim[i][i];
1.208     brouard  6229:        mgp[theta][i] = prlim[i][i];
                   6230:       }
1.126     brouard  6231:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6232:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6233:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6234:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6235:       else
1.235     brouard  6236:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6237:       for(i=1;i<=nlstate;i++){
1.126     brouard  6238:        gm[i] = prlim[i][i];
1.208     brouard  6239:        mgm[theta][i] = prlim[i][i];
                   6240:       }
1.126     brouard  6241:       for(i=1;i<=nlstate;i++)
                   6242:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6243:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6244:     } /* End theta */
                   6245: 
                   6246:     trgradg =matrix(1,nlstate,1,npar);
                   6247: 
                   6248:     for(j=1; j<=nlstate;j++)
                   6249:       for(theta=1; theta <=npar; theta++)
                   6250:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6251:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6252:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6253:     /*   for(j=1; j<=nlstate;j++){ */
                   6254:     /*         printf(" %d ",j); */
                   6255:     /*         for(theta=1; theta <=npar; theta++) */
                   6256:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6257:     /*         printf("\n "); */
                   6258:     /*   } */
                   6259:     /* } */
                   6260:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6261:     /*   printf("\n gradg %d ",(int)age); */
                   6262:     /*   for(j=1; j<=nlstate;j++){ */
                   6263:     /*         printf("%d ",j); */
                   6264:     /*         for(theta=1; theta <=npar; theta++) */
                   6265:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6266:     /*         printf("\n "); */
                   6267:     /*   } */
                   6268:     /* } */
1.126     brouard  6269: 
                   6270:     for(i=1;i<=nlstate;i++)
                   6271:       varpl[i][(int)age] =0.;
1.209     brouard  6272:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6273:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6274:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6275:     }else{
1.268     brouard  6276:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6277:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6278:     }
1.126     brouard  6279:     for(i=1;i<=nlstate;i++)
                   6280:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6281: 
                   6282:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6283:     if(nresult >=1)
                   6284:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6285:     for(i=1; i<=nlstate;i++)
                   6286:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6287:     fprintf(ficresvpl,"\n");
                   6288:     free_vector(gp,1,nlstate);
                   6289:     free_vector(gm,1,nlstate);
1.208     brouard  6290:     free_matrix(mgm,1,npar,1,nlstate);
                   6291:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6292:     free_matrix(gradg,1,npar,1,nlstate);
                   6293:     free_matrix(trgradg,1,nlstate,1,npar);
                   6294:   } /* End age */
                   6295: 
                   6296:   free_vector(xp,1,npar);
                   6297:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6298:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6299: 
                   6300: }
                   6301: 
                   6302: 
                   6303: /************ Variance of backprevalence limit ******************/
1.269     brouard  6304:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6305: {
                   6306:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6307:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6308: 
                   6309:   double **dnewmpar,**doldm;
                   6310:   int i, j, nhstepm, hstepm;
                   6311:   double *xp;
                   6312:   double *gp, *gm;
                   6313:   double **gradg, **trgradg;
                   6314:   double **mgm, **mgp;
                   6315:   double age,agelim;
                   6316:   int theta;
                   6317:   
                   6318:   pstamp(ficresvbl);
                   6319:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6320:   fprintf(ficresvbl,"# Age ");
                   6321:   if(nresult >=1)
                   6322:     fprintf(ficresvbl," Result# ");
                   6323:   for(i=1; i<=nlstate;i++)
                   6324:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6325:   fprintf(ficresvbl,"\n");
                   6326: 
                   6327:   xp=vector(1,npar);
                   6328:   dnewmpar=matrix(1,nlstate,1,npar);
                   6329:   doldm=matrix(1,nlstate,1,nlstate);
                   6330:   
                   6331:   hstepm=1*YEARM; /* Every year of age */
                   6332:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6333:   agelim = AGEINF;
                   6334:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6335:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6336:     if (stepm >= YEARM) hstepm=1;
                   6337:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6338:     gradg=matrix(1,npar,1,nlstate);
                   6339:     mgp=matrix(1,npar,1,nlstate);
                   6340:     mgm=matrix(1,npar,1,nlstate);
                   6341:     gp=vector(1,nlstate);
                   6342:     gm=vector(1,nlstate);
                   6343: 
                   6344:     for(theta=1; theta <=npar; theta++){
                   6345:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6346:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6347:       }
                   6348:       if(mobilavproj > 0 )
                   6349:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6350:       else
                   6351:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6352:       for(i=1;i<=nlstate;i++){
                   6353:        gp[i] = bprlim[i][i];
                   6354:        mgp[theta][i] = bprlim[i][i];
                   6355:       }
                   6356:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6357:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6358:        if(mobilavproj > 0 )
                   6359:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6360:        else
                   6361:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6362:       for(i=1;i<=nlstate;i++){
                   6363:        gm[i] = bprlim[i][i];
                   6364:        mgm[theta][i] = bprlim[i][i];
                   6365:       }
                   6366:       for(i=1;i<=nlstate;i++)
                   6367:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6368:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6369:     } /* End theta */
                   6370: 
                   6371:     trgradg =matrix(1,nlstate,1,npar);
                   6372: 
                   6373:     for(j=1; j<=nlstate;j++)
                   6374:       for(theta=1; theta <=npar; theta++)
                   6375:        trgradg[j][theta]=gradg[theta][j];
                   6376:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6377:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6378:     /*   for(j=1; j<=nlstate;j++){ */
                   6379:     /*         printf(" %d ",j); */
                   6380:     /*         for(theta=1; theta <=npar; theta++) */
                   6381:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6382:     /*         printf("\n "); */
                   6383:     /*   } */
                   6384:     /* } */
                   6385:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6386:     /*   printf("\n gradg %d ",(int)age); */
                   6387:     /*   for(j=1; j<=nlstate;j++){ */
                   6388:     /*         printf("%d ",j); */
                   6389:     /*         for(theta=1; theta <=npar; theta++) */
                   6390:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6391:     /*         printf("\n "); */
                   6392:     /*   } */
                   6393:     /* } */
                   6394: 
                   6395:     for(i=1;i<=nlstate;i++)
                   6396:       varbpl[i][(int)age] =0.;
                   6397:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6398:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6399:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6400:     }else{
                   6401:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6402:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6403:     }
                   6404:     for(i=1;i<=nlstate;i++)
                   6405:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6406: 
                   6407:     fprintf(ficresvbl,"%.0f ",age );
                   6408:     if(nresult >=1)
                   6409:       fprintf(ficresvbl,"%d ",nres );
                   6410:     for(i=1; i<=nlstate;i++)
                   6411:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6412:     fprintf(ficresvbl,"\n");
                   6413:     free_vector(gp,1,nlstate);
                   6414:     free_vector(gm,1,nlstate);
                   6415:     free_matrix(mgm,1,npar,1,nlstate);
                   6416:     free_matrix(mgp,1,npar,1,nlstate);
                   6417:     free_matrix(gradg,1,npar,1,nlstate);
                   6418:     free_matrix(trgradg,1,nlstate,1,npar);
                   6419:   } /* End age */
                   6420: 
                   6421:   free_vector(xp,1,npar);
                   6422:   free_matrix(doldm,1,nlstate,1,npar);
                   6423:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6424: 
                   6425: }
                   6426: 
                   6427: /************ Variance of one-step probabilities  ******************/
                   6428: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6429:  {
                   6430:    int i, j=0,  k1, l1, tj;
                   6431:    int k2, l2, j1,  z1;
                   6432:    int k=0, l;
                   6433:    int first=1, first1, first2;
                   6434:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6435:    double **dnewm,**doldm;
                   6436:    double *xp;
                   6437:    double *gp, *gm;
                   6438:    double **gradg, **trgradg;
                   6439:    double **mu;
                   6440:    double age, cov[NCOVMAX+1];
                   6441:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6442:    int theta;
                   6443:    char fileresprob[FILENAMELENGTH];
                   6444:    char fileresprobcov[FILENAMELENGTH];
                   6445:    char fileresprobcor[FILENAMELENGTH];
                   6446:    double ***varpij;
                   6447: 
                   6448:    strcpy(fileresprob,"PROB_"); 
                   6449:    strcat(fileresprob,fileres);
                   6450:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6451:      printf("Problem with resultfile: %s\n", fileresprob);
                   6452:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6453:    }
                   6454:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6455:    strcat(fileresprobcov,fileresu);
                   6456:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6457:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6458:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6459:    }
                   6460:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6461:    strcat(fileresprobcor,fileresu);
                   6462:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6463:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6464:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6465:    }
                   6466:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6467:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6468:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6469:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6470:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6471:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6472:    pstamp(ficresprob);
                   6473:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6474:    fprintf(ficresprob,"# Age");
                   6475:    pstamp(ficresprobcov);
                   6476:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6477:    fprintf(ficresprobcov,"# Age");
                   6478:    pstamp(ficresprobcor);
                   6479:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6480:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6481: 
                   6482: 
1.222     brouard  6483:    for(i=1; i<=nlstate;i++)
                   6484:      for(j=1; j<=(nlstate+ndeath);j++){
                   6485:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6486:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6487:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6488:      }  
                   6489:    /* fprintf(ficresprob,"\n");
                   6490:       fprintf(ficresprobcov,"\n");
                   6491:       fprintf(ficresprobcor,"\n");
                   6492:    */
                   6493:    xp=vector(1,npar);
                   6494:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6495:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6496:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6497:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6498:    first=1;
                   6499:    fprintf(ficgp,"\n# Routine varprob");
                   6500:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6501:    fprintf(fichtm,"\n");
                   6502: 
1.266     brouard  6503:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6504:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6505:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6506: and drawn. It helps understanding how is the covariance between two incidences.\
                   6507:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6508:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6509: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6510: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6511: standard deviations wide on each axis. <br>\
                   6512:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6513:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6514: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6515: 
1.222     brouard  6516:    cov[1]=1;
                   6517:    /* tj=cptcoveff; */
1.225     brouard  6518:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6519:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6520:    j1=0;
1.224     brouard  6521:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6522:      if  (cptcovn>0) {
                   6523:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6524:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6525:        fprintf(ficresprob, "**********\n#\n");
                   6526:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6527:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6528:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6529:                        
1.222     brouard  6530:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6531:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6532:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6533:                        
                   6534:                        
1.222     brouard  6535:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6536:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6537:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6538:                        
1.222     brouard  6539:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6540:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6541:        fprintf(ficresprobcor, "**********\n#");    
                   6542:        if(invalidvarcomb[j1]){
                   6543:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6544:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6545:         continue;
                   6546:        }
                   6547:      }
                   6548:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6549:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6550:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6551:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6552:      for (age=bage; age<=fage; age ++){ 
                   6553:        cov[2]=age;
                   6554:        if(nagesqr==1)
                   6555:         cov[3]= age*age;
                   6556:        for (k=1; k<=cptcovn;k++) {
                   6557:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6558:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6559:                                                                    * 1  1 1 1 1
                   6560:                                                                    * 2  2 1 1 1
                   6561:                                                                    * 3  1 2 1 1
                   6562:                                                                    */
                   6563:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6564:        }
                   6565:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6566:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6567:        for (k=1; k<=cptcovprod;k++)
                   6568:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6569:                        
                   6570:                        
1.222     brouard  6571:        for(theta=1; theta <=npar; theta++){
                   6572:         for(i=1; i<=npar; i++)
                   6573:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6574:                                
1.222     brouard  6575:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6576:                                
1.222     brouard  6577:         k=0;
                   6578:         for(i=1; i<= (nlstate); i++){
                   6579:           for(j=1; j<=(nlstate+ndeath);j++){
                   6580:             k=k+1;
                   6581:             gp[k]=pmmij[i][j];
                   6582:           }
                   6583:         }
1.220     brouard  6584:                                
1.222     brouard  6585:         for(i=1; i<=npar; i++)
                   6586:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6587:                                
1.222     brouard  6588:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6589:         k=0;
                   6590:         for(i=1; i<=(nlstate); i++){
                   6591:           for(j=1; j<=(nlstate+ndeath);j++){
                   6592:             k=k+1;
                   6593:             gm[k]=pmmij[i][j];
                   6594:           }
                   6595:         }
1.220     brouard  6596:                                
1.222     brouard  6597:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6598:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6599:        }
1.126     brouard  6600: 
1.222     brouard  6601:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6602:         for(theta=1; theta <=npar; theta++)
                   6603:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6604:                        
1.222     brouard  6605:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6606:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6607:                        
1.222     brouard  6608:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6609:                        
1.222     brouard  6610:        k=0;
                   6611:        for(i=1; i<=(nlstate); i++){
                   6612:         for(j=1; j<=(nlstate+ndeath);j++){
                   6613:           k=k+1;
                   6614:           mu[k][(int) age]=pmmij[i][j];
                   6615:         }
                   6616:        }
                   6617:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6618:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6619:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6620:                        
1.222     brouard  6621:        /*printf("\n%d ",(int)age);
                   6622:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6623:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6624:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6625:         }*/
1.220     brouard  6626:                        
1.222     brouard  6627:        fprintf(ficresprob,"\n%d ",(int)age);
                   6628:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6629:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6630:                        
1.222     brouard  6631:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6632:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6633:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6634:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6635:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6636:        }
                   6637:        i=0;
                   6638:        for (k=1; k<=(nlstate);k++){
                   6639:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6640:           i++;
                   6641:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6642:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6643:           for (j=1; j<=i;j++){
                   6644:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6645:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6646:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6647:           }
                   6648:         }
                   6649:        }/* end of loop for state */
                   6650:      } /* end of loop for age */
                   6651:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6652:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6653:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6654:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6655:     
                   6656:      /* Confidence intervalle of pij  */
                   6657:      /*
                   6658:        fprintf(ficgp,"\nunset parametric;unset label");
                   6659:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6660:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6661:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6662:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6663:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6664:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6665:      */
                   6666:                
                   6667:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6668:      first1=1;first2=2;
                   6669:      for (k2=1; k2<=(nlstate);k2++){
                   6670:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6671:         if(l2==k2) continue;
                   6672:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6673:         for (k1=1; k1<=(nlstate);k1++){
                   6674:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6675:             if(l1==k1) continue;
                   6676:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6677:             if(i<=j) continue;
                   6678:             for (age=bage; age<=fage; age ++){ 
                   6679:               if ((int)age %5==0){
                   6680:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6681:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6682:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6683:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6684:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6685:                 c12=cv12/sqrt(v1*v2);
                   6686:                 /* Computing eigen value of matrix of covariance */
                   6687:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6688:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6689:                 if ((lc2 <0) || (lc1 <0) ){
                   6690:                   if(first2==1){
                   6691:                     first1=0;
                   6692:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6693:                   }
                   6694:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6695:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6696:                   /* lc2=fabs(lc2); */
                   6697:                 }
1.220     brouard  6698:                                                                
1.222     brouard  6699:                 /* Eigen vectors */
1.280     brouard  6700:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6701:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6702:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6703:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6704:                 }else
                   6705:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6706:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6707:                 v21=(lc1-v1)/cv12*v11;
                   6708:                 v12=-v21;
                   6709:                 v22=v11;
                   6710:                 tnalp=v21/v11;
                   6711:                 if(first1==1){
                   6712:                   first1=0;
                   6713:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6714:                 }
                   6715:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6716:                 /*printf(fignu*/
                   6717:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6718:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6719:                 if(first==1){
                   6720:                   first=0;
                   6721:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6722:                   fprintf(ficgp,"\nset parametric;unset label");
                   6723:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6724:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6725:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6726:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6727: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6728:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6729:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6730:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6731:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6732:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6733:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6734:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6735:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6736:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6737:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6738:                 }else{
                   6739:                   first=0;
                   6740:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6741:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6742:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6743:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6744:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6745:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6746:                 }/* if first */
                   6747:               } /* age mod 5 */
                   6748:             } /* end loop age */
                   6749:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6750:             first=1;
                   6751:           } /*l12 */
                   6752:         } /* k12 */
                   6753:        } /*l1 */
                   6754:      }/* k1 */
                   6755:    }  /* loop on combination of covariates j1 */
                   6756:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6757:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6758:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6759:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6760:    free_vector(xp,1,npar);
                   6761:    fclose(ficresprob);
                   6762:    fclose(ficresprobcov);
                   6763:    fclose(ficresprobcor);
                   6764:    fflush(ficgp);
                   6765:    fflush(fichtmcov);
                   6766:  }
1.126     brouard  6767: 
                   6768: 
                   6769: /******************* Printing html file ***********/
1.201     brouard  6770: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6771:                  int lastpass, int stepm, int weightopt, char model[],\
                   6772:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6773:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6774:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6775:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6776:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6777: 
                   6778:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6779:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6780: </ul>");
1.237     brouard  6781:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6782: </ul>", model);
1.214     brouard  6783:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6784:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6785:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6786:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6787:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6788:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6789:    fprintf(fichtm,"\
                   6790:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6791:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6792:    fprintf(fichtm,"\
1.217     brouard  6793:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6794:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6795:    fprintf(fichtm,"\
1.126     brouard  6796:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6797:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6798:    fprintf(fichtm,"\
1.217     brouard  6799:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6800:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6801:    fprintf(fichtm,"\
1.211     brouard  6802:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6803:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6804:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6805:    if(prevfcast==1){
                   6806:      fprintf(fichtm,"\
                   6807:  - Prevalence projections by age and states:                           \
1.201     brouard  6808:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6809:    }
1.126     brouard  6810: 
                   6811: 
1.225     brouard  6812:    m=pow(2,cptcoveff);
1.222     brouard  6813:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6814: 
1.264     brouard  6815:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6816: 
                   6817:    jj1=0;
                   6818: 
                   6819:    fprintf(fichtm," \n<ul>");
                   6820:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6821:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6822:      if(m != 1 && TKresult[nres]!= k1)
                   6823:        continue;
                   6824:      jj1++;
                   6825:      if (cptcovn > 0) {
                   6826:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6827:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6828:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6829:        }
                   6830:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6831:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6832:        }
                   6833:        fprintf(fichtm,"\">");
                   6834:        
                   6835:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6836:        fprintf(fichtm,"************ Results for covariates");
                   6837:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6838:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6839:        }
                   6840:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6841:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6842:        }
                   6843:        if(invalidvarcomb[k1]){
                   6844:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6845:         continue;
                   6846:        }
                   6847:        fprintf(fichtm,"</a></li>");
                   6848:      } /* cptcovn >0 */
                   6849:    }
                   6850:      fprintf(fichtm," \n</ul>");
                   6851: 
1.222     brouard  6852:    jj1=0;
1.237     brouard  6853: 
                   6854:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6855:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6856:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6857:        continue;
1.220     brouard  6858: 
1.222     brouard  6859:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6860:      jj1++;
                   6861:      if (cptcovn > 0) {
1.264     brouard  6862:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6863:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6864:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6865:        }
                   6866:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6867:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6868:        }
                   6869:        fprintf(fichtm,"\"</a>");
                   6870:  
1.222     brouard  6871:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6872:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6873:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6874:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6875:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6876:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6877:        }
1.237     brouard  6878:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6879:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6880:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6881:       }
                   6882:        
1.230     brouard  6883:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6884:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6885:        if(invalidvarcomb[k1]){
                   6886:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6887:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6888:         continue;
                   6889:        }
                   6890:      }
                   6891:      /* aij, bij */
1.259     brouard  6892:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6893: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6894:      /* Pij */
1.241     brouard  6895:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6896: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6897:      /* Quasi-incidences */
                   6898:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6899:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6900:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6901: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6902: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6903:      /* Survival functions (period) in state j */
                   6904:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6905:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6906: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6907:      }
                   6908:      /* State specific survival functions (period) */
                   6909:      for(cpt=1; cpt<=nlstate;cpt++){
                   6910:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6911:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6912:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6913:      }
                   6914:      /* Period (stable) prevalence in each health state */
                   6915:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6916:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6917: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6918:      }
                   6919:      if(backcast==1){
                   6920:        /* Period (stable) back prevalence in each health state */
                   6921:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6922:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6923: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6924:        }
1.217     brouard  6925:      }
1.222     brouard  6926:      if(prevfcast==1){
                   6927:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6928:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6929:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6930: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6931:        }
                   6932:      }
1.268     brouard  6933:      if(backcast==1){
                   6934:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6935:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6936:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6937:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6938:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6939: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6940:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6941:        }
                   6942:      }
1.220     brouard  6943:         
1.222     brouard  6944:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6945:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6946: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6947:      }
                   6948:      /* } /\* end i1 *\/ */
                   6949:    }/* End k1 */
                   6950:    fprintf(fichtm,"</ul>");
1.126     brouard  6951: 
1.222     brouard  6952:    fprintf(fichtm,"\
1.126     brouard  6953: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6954:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6955:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6956: But because parameters are usually highly correlated (a higher incidence of disability \
                   6957: and a higher incidence of recovery can give very close observed transition) it might \
                   6958: be very useful to look not only at linear confidence intervals estimated from the \
                   6959: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6960: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6961: covariance matrix of the one-step probabilities. \
                   6962: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6963: 
1.222     brouard  6964:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6965:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6966:    fprintf(fichtm,"\
1.126     brouard  6967:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6968:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6969: 
1.222     brouard  6970:    fprintf(fichtm,"\
1.126     brouard  6971:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6972:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6973:    fprintf(fichtm,"\
1.126     brouard  6974:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6975:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6976:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6977:    fprintf(fichtm,"\
1.126     brouard  6978:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6979:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6980:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6981:    fprintf(fichtm,"\
1.128     brouard  6982:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6983:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6984:    fprintf(fichtm,"\
1.128     brouard  6985:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6986:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6987:    fprintf(fichtm,"\
1.126     brouard  6988:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6989:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6990: 
                   6991: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6992: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6993: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6994: /*     <br>",fileres,fileres,fileres,fileres); */
                   6995: /*  else  */
                   6996: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6997:    fflush(fichtm);
                   6998:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6999: 
1.225     brouard  7000:    m=pow(2,cptcoveff);
1.222     brouard  7001:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7002: 
1.222     brouard  7003:    jj1=0;
1.237     brouard  7004: 
1.241     brouard  7005:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7006:    for(k1=1; k1<=m;k1++){
1.253     brouard  7007:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7008:        continue;
1.222     brouard  7009:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7010:      jj1++;
1.126     brouard  7011:      if (cptcovn > 0) {
                   7012:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7013:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7014:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7015:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7016:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7017:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7018:       }
                   7019: 
1.126     brouard  7020:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7021: 
1.222     brouard  7022:        if(invalidvarcomb[k1]){
                   7023:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7024:         continue;
                   7025:        }
1.126     brouard  7026:      }
                   7027:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7028:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7029: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7030: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7031:      }
                   7032:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7033: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7034: true period expectancies (those weighted with period prevalences are also\
                   7035:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7036:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7037: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7038:      /* } /\* end i1 *\/ */
                   7039:    }/* End k1 */
1.241     brouard  7040:   }/* End nres */
1.222     brouard  7041:    fprintf(fichtm,"</ul>");
                   7042:    fflush(fichtm);
1.126     brouard  7043: }
                   7044: 
                   7045: /******************* Gnuplot file **************/
1.270     brouard  7046: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7047: 
                   7048:   char dirfileres[132],optfileres[132];
1.264     brouard  7049:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7050:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7051:   int lv=0, vlv=0, kl=0;
1.130     brouard  7052:   int ng=0;
1.201     brouard  7053:   int vpopbased;
1.223     brouard  7054:   int ioffset; /* variable offset for columns */
1.270     brouard  7055:   int iyearc=1; /* variable column for year of projection  */
                   7056:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7057:   int nres=0; /* Index of resultline */
1.266     brouard  7058:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7059: 
1.126     brouard  7060: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7061: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7062: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7063: /*   } */
                   7064: 
                   7065:   /*#ifdef windows */
                   7066:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7067:   /*#endif */
1.225     brouard  7068:   m=pow(2,cptcoveff);
1.126     brouard  7069: 
1.274     brouard  7070:   /* diagram of the model */
                   7071:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7072:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7073:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7074:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7075: 
                   7076:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7077:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7078:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7079:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7080:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7081:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7082:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7083: 
1.202     brouard  7084:   /* Contribution to likelihood */
                   7085:   /* Plot the probability implied in the likelihood */
1.223     brouard  7086:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7087:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7088:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7089:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7090: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7091:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7092: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7093:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7094:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7095:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7096:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7097:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7098:   for (i=1; i<= nlstate ; i ++) {
                   7099:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7100:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7101:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7102:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7103:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7104:     }
                   7105:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7106:   }
                   7107:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7108:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7109:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7110:   fprintf(ficgp,"\nset out;unset log\n");
                   7111:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7112: 
1.126     brouard  7113:   strcpy(dirfileres,optionfilefiname);
                   7114:   strcpy(optfileres,"vpl");
1.223     brouard  7115:   /* 1eme*/
1.238     brouard  7116:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7117:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7118:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7119:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7120:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7121:          continue;
                   7122:        /* We are interested in selected combination by the resultline */
1.246     brouard  7123:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7124:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7125:        strcpy(gplotlabel,"(");
1.238     brouard  7126:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7127:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7128:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7129:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7130:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7131:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7132:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7133:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7134:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7135:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7136:        }
                   7137:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7138:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7139:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7140:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7141:        }
                   7142:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7143:        /* printf("\n#\n"); */
1.238     brouard  7144:        fprintf(ficgp,"\n#\n");
                   7145:        if(invalidvarcomb[k1]){
1.260     brouard  7146:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7147:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7148:          continue;
                   7149:        }
1.235     brouard  7150:       
1.241     brouard  7151:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7152:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7153:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7154:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7155:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7156:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7157:       /* k1-1 error should be nres-1*/
1.238     brouard  7158:        for (i=1; i<= nlstate ; i ++) {
                   7159:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7160:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7161:        }
1.260     brouard  7162:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7163:        for (i=1; i<= nlstate ; i ++) {
                   7164:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7165:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7166:        } 
1.260     brouard  7167:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7168:        for (i=1; i<= nlstate ; i ++) {
                   7169:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7170:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7171:        }  
1.265     brouard  7172:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7173:        
                   7174:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7175:         if(cptcoveff ==0){
1.271     brouard  7176:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7177:        }else{
                   7178:          kl=0;
                   7179:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7180:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7181:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7182:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7183:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7184:            vlv= nbcode[Tvaraff[k]][lv];
                   7185:            kl++;
                   7186:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7187:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7188:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7189:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7190:            if(k==cptcoveff){
                   7191:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7192:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7193:            }else{
                   7194:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7195:              kl++;
                   7196:            }
                   7197:          } /* end covariate */
                   7198:        } /* end if no covariate */
                   7199: 
1.238     brouard  7200:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7201:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7202:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7203:          if(cptcoveff ==0){
1.245     brouard  7204:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7205:          }else{
                   7206:            kl=0;
                   7207:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7208:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7209:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7210:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7211:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7212:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7213:              kl++;
1.238     brouard  7214:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7215:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7216:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7217:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7218:              if(k==cptcoveff){
1.245     brouard  7219:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7220:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7221:              }else{
                   7222:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7223:                kl++;
                   7224:              }
                   7225:            } /* end covariate */
                   7226:          } /* end if no covariate */
1.268     brouard  7227:          if(backcast == 1){
                   7228:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7229:            /* k1-1 error should be nres-1*/
                   7230:            for (i=1; i<= nlstate ; i ++) {
                   7231:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7232:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7233:            }
1.271     brouard  7234:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7235:            for (i=1; i<= nlstate ; i ++) {
                   7236:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7237:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7238:            } 
1.276     brouard  7239:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7240:            for (i=1; i<= nlstate ; i ++) {
                   7241:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7242:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7243:            } 
1.274     brouard  7244:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7245:          } /* end if backprojcast */
1.238     brouard  7246:        } /* end if backcast */
1.276     brouard  7247:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7248:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7249:       } /* nres */
1.201     brouard  7250:     } /* k1 */
                   7251:   } /* cpt */
1.235     brouard  7252: 
                   7253:   
1.126     brouard  7254:   /*2 eme*/
1.238     brouard  7255:   for (k1=1; k1<= m ; k1 ++){  
                   7256:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7257:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7258:        continue;
                   7259:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7260:       strcpy(gplotlabel,"(");
1.238     brouard  7261:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7262:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7263:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7264:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7265:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7266:        vlv= nbcode[Tvaraff[k]][lv];
                   7267:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7268:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7269:       }
1.237     brouard  7270:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7271:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7272:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7273:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7274:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7275:       }
1.264     brouard  7276:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7277:       fprintf(ficgp,"\n#\n");
1.223     brouard  7278:       if(invalidvarcomb[k1]){
                   7279:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7280:        continue;
                   7281:       }
1.219     brouard  7282:                        
1.241     brouard  7283:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7284:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7285:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7286:        if(vpopbased==0){
1.238     brouard  7287:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7288:        }else
1.238     brouard  7289:          fprintf(ficgp,"\nreplot ");
                   7290:        for (i=1; i<= nlstate+1 ; i ++) {
                   7291:          k=2*i;
1.261     brouard  7292:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7293:          for (j=1; j<= nlstate+1 ; j ++) {
                   7294:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7295:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7296:          }   
                   7297:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7298:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7299:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7300:          for (j=1; j<= nlstate+1 ; j ++) {
                   7301:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7302:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7303:          }   
                   7304:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7305:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7306:          for (j=1; j<= nlstate+1 ; j ++) {
                   7307:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7308:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7309:          }   
                   7310:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7311:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7312:        } /* state */
                   7313:       } /* vpopbased */
1.264     brouard  7314:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7315:     } /* end nres */
                   7316:   } /* k1 end 2 eme*/
                   7317:        
                   7318:        
                   7319:   /*3eme*/
                   7320:   for (k1=1; k1<= m ; k1 ++){
                   7321:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7322:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7323:        continue;
                   7324: 
                   7325:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7326:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7327:        strcpy(gplotlabel,"(");
1.238     brouard  7328:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7329:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7330:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7331:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7332:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7333:          vlv= nbcode[Tvaraff[k]][lv];
                   7334:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7335:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7336:        }
                   7337:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7338:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7339:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7340:        }       
1.264     brouard  7341:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7342:        fprintf(ficgp,"\n#\n");
                   7343:        if(invalidvarcomb[k1]){
                   7344:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7345:          continue;
                   7346:        }
                   7347:                        
                   7348:        /*       k=2+nlstate*(2*cpt-2); */
                   7349:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7350:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7351:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7352:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7353: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7354:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7355:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7356:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7357:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7358:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7359:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7360:                                
1.238     brouard  7361:        */
                   7362:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7363:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7364:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7365:                                
1.238     brouard  7366:        } 
1.261     brouard  7367:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7368:       }
1.264     brouard  7369:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7370:     } /* end nres */
                   7371:   } /* end kl 3eme */
1.126     brouard  7372:   
1.223     brouard  7373:   /* 4eme */
1.201     brouard  7374:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7375:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7376:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7377:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7378:        continue;
1.238     brouard  7379:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7380:        strcpy(gplotlabel,"(");
1.238     brouard  7381:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7382:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7383:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7384:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7385:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7386:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7387:          vlv= nbcode[Tvaraff[k]][lv];
                   7388:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7389:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7390:        }
                   7391:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7392:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7393:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7394:        }       
1.264     brouard  7395:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7396:        fprintf(ficgp,"\n#\n");
                   7397:        if(invalidvarcomb[k1]){
                   7398:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7399:          continue;
1.223     brouard  7400:        }
1.238     brouard  7401:       
1.241     brouard  7402:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7403:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7404:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7405: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7406:        k=3;
                   7407:        for (i=1; i<= nlstate ; i ++){
                   7408:          if(i==1){
                   7409:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7410:          }else{
                   7411:            fprintf(ficgp,", '' ");
                   7412:          }
                   7413:          l=(nlstate+ndeath)*(i-1)+1;
                   7414:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7415:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7416:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7417:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7418:        } /* nlstate */
1.264     brouard  7419:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7420:       } /* end cpt state*/ 
                   7421:     } /* end nres */
                   7422:   } /* end covariate k1 */  
                   7423: 
1.220     brouard  7424: /* 5eme */
1.201     brouard  7425:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7426:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7427:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7428:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7429:        continue;
1.238     brouard  7430:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7431:        strcpy(gplotlabel,"(");
1.238     brouard  7432:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7433:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7434:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7435:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7436:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7437:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7438:          vlv= nbcode[Tvaraff[k]][lv];
                   7439:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7440:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7441:        }
                   7442:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7443:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7444:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7445:        }       
1.264     brouard  7446:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7447:        fprintf(ficgp,"\n#\n");
                   7448:        if(invalidvarcomb[k1]){
                   7449:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7450:          continue;
                   7451:        }
1.227     brouard  7452:       
1.241     brouard  7453:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7454:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7455:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7456: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7457:        k=3;
                   7458:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7459:          if(j==1)
                   7460:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7461:          else
                   7462:            fprintf(ficgp,", '' ");
                   7463:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7464:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7465:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7466:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7467:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7468:        } /* nlstate */
                   7469:        fprintf(ficgp,", '' ");
                   7470:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7471:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7472:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7473:          if(j < nlstate)
                   7474:            fprintf(ficgp,"$%d +",k+l);
                   7475:          else
                   7476:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7477:        }
1.264     brouard  7478:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7479:       } /* end cpt state*/ 
                   7480:     } /* end covariate */  
                   7481:   } /* end nres */
1.227     brouard  7482:   
1.220     brouard  7483: /* 6eme */
1.202     brouard  7484:   /* CV preval stable (period) for each covariate */
1.237     brouard  7485:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7486:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7487:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7488:       continue;
1.255     brouard  7489:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7490:       strcpy(gplotlabel,"(");      
1.211     brouard  7491:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7492:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7493:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7494:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7495:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7496:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7497:        vlv= nbcode[Tvaraff[k]][lv];
                   7498:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7499:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7500:       }
1.237     brouard  7501:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7502:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7503:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7504:       }        
1.264     brouard  7505:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7506:       fprintf(ficgp,"\n#\n");
1.223     brouard  7507:       if(invalidvarcomb[k1]){
1.227     brouard  7508:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7509:        continue;
1.223     brouard  7510:       }
1.227     brouard  7511:       
1.241     brouard  7512:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7513:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7514:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7515: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7516:       k=3; /* Offset */
1.255     brouard  7517:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7518:        if(i==1)
                   7519:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7520:        else
                   7521:          fprintf(ficgp,", '' ");
1.255     brouard  7522:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7523:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7524:        for (j=2; j<= nlstate ; j ++)
                   7525:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7526:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7527:       } /* nlstate */
1.264     brouard  7528:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7529:     } /* end cpt state*/ 
                   7530:   } /* end covariate */  
1.227     brouard  7531:   
                   7532:   
1.220     brouard  7533: /* 7eme */
1.218     brouard  7534:   if(backcast == 1){
1.217     brouard  7535:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7536:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7537:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7538:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7539:        continue;
1.268     brouard  7540:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7541:        strcpy(gplotlabel,"(");      
                   7542:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7543:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7544:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7545:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7546:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7547:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7548:          vlv= nbcode[Tvaraff[k]][lv];
                   7549:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7550:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7551:        }
1.237     brouard  7552:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7553:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7554:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7555:        }       
1.264     brouard  7556:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7557:        fprintf(ficgp,"\n#\n");
                   7558:        if(invalidvarcomb[k1]){
                   7559:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7560:          continue;
                   7561:        }
                   7562:        
1.241     brouard  7563:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7564:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7565:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7566: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7567:        k=3; /* Offset */
1.268     brouard  7568:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7569:          if(i==1)
                   7570:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7571:          else
                   7572:            fprintf(ficgp,", '' ");
                   7573:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7574:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7575:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7576:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7577:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7578:          /* for (j=2; j<= nlstate ; j ++) */
                   7579:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7580:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7581:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7582:        } /* nlstate */
1.264     brouard  7583:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7584:       } /* end cpt state*/ 
                   7585:     } /* end covariate */  
                   7586:   } /* End if backcast */
                   7587:   
1.223     brouard  7588:   /* 8eme */
1.218     brouard  7589:   if(prevfcast==1){
                   7590:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7591:     
1.237     brouard  7592:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7593:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7594:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7595:        continue;
1.211     brouard  7596:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7597:        strcpy(gplotlabel,"(");      
1.227     brouard  7598:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7599:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7600:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7601:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7602:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7603:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7604:          vlv= nbcode[Tvaraff[k]][lv];
                   7605:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7606:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7607:        }
1.237     brouard  7608:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7609:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7610:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7611:        }       
1.264     brouard  7612:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7613:        fprintf(ficgp,"\n#\n");
                   7614:        if(invalidvarcomb[k1]){
                   7615:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7616:          continue;
                   7617:        }
                   7618:        
                   7619:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7620:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7621:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7622:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7623: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7624: 
                   7625:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7626:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7627:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7628:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7629:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7630:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7631:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7632:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7633:          if(i==istart){
1.227     brouard  7634:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7635:          }else{
                   7636:            fprintf(ficgp,",\\\n '' ");
                   7637:          }
                   7638:          if(cptcoveff ==0){ /* No covariate */
                   7639:            ioffset=2; /* Age is in 2 */
                   7640:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7641:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7642:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7643:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7644:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7645:            if(i==nlstate+1){
1.270     brouard  7646:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7647:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7648:              fprintf(ficgp,",\\\n '' ");
                   7649:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7650:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7651:                     offyear,                           \
1.268     brouard  7652:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7653:            }else
1.227     brouard  7654:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7655:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7656:          }else{ /* more than 2 covariates */
1.270     brouard  7657:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7658:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7659:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7660:            iyearc=ioffset-1;
                   7661:            iagec=ioffset;
1.227     brouard  7662:            fprintf(ficgp," u %d:(",ioffset); 
                   7663:            kl=0;
                   7664:            strcpy(gplotcondition,"(");
                   7665:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7666:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7667:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7668:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7669:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7670:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7671:              kl++;
                   7672:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7673:              kl++;
                   7674:              if(k <cptcoveff && cptcoveff>1)
                   7675:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7676:            }
                   7677:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7678:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7679:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7680:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7681:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7682:            if(i==nlstate+1){
1.270     brouard  7683:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7684:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7685:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7686:              fprintf(ficgp," u %d:(",iagec); 
                   7687:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7688:                      iyearc, iagec, offyear,                           \
                   7689:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7690: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7691:            }else{
                   7692:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7693:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7694:            }
                   7695:          } /* end if covariate */
                   7696:        } /* nlstate */
1.264     brouard  7697:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7698:       } /* end cpt state*/
                   7699:     } /* end covariate */
                   7700:   } /* End if prevfcast */
1.227     brouard  7701:   
1.268     brouard  7702:   if(backcast==1){
                   7703:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7704:     
                   7705:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7706:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7707:       if(m != 1 && TKresult[nres]!= k1)
                   7708:        continue;
                   7709:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7710:        strcpy(gplotlabel,"(");      
                   7711:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7712:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7713:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7714:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7715:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7716:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7717:          vlv= nbcode[Tvaraff[k]][lv];
                   7718:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7719:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7720:        }
                   7721:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7722:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7723:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7724:        }       
                   7725:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7726:        fprintf(ficgp,"\n#\n");
                   7727:        if(invalidvarcomb[k1]){
                   7728:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7729:          continue;
                   7730:        }
                   7731:        
                   7732:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7733:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7734:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7735:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7736: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7737: 
                   7738:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7739:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7740:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7741:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7742:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7743:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7744:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7745:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7746:          if(i==istart){
                   7747:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7748:          }else{
                   7749:            fprintf(ficgp,",\\\n '' ");
                   7750:          }
                   7751:          if(cptcoveff ==0){ /* No covariate */
                   7752:            ioffset=2; /* Age is in 2 */
                   7753:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7754:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7755:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7756:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7757:            fprintf(ficgp," u %d:(", ioffset); 
                   7758:            if(i==nlstate+1){
1.270     brouard  7759:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7760:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7761:              fprintf(ficgp,",\\\n '' ");
                   7762:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7763:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7764:                     offbyear,                          \
                   7765:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7766:            }else
                   7767:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7768:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7769:          }else{ /* more than 2 covariates */
1.270     brouard  7770:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7771:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7772:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7773:            iyearc=ioffset-1;
                   7774:            iagec=ioffset;
1.268     brouard  7775:            fprintf(ficgp," u %d:(",ioffset); 
                   7776:            kl=0;
                   7777:            strcpy(gplotcondition,"(");
                   7778:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7779:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7780:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7781:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7782:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7783:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7784:              kl++;
                   7785:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7786:              kl++;
                   7787:              if(k <cptcoveff && cptcoveff>1)
                   7788:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7789:            }
                   7790:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7791:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7792:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7793:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7794:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7795:            if(i==nlstate+1){
1.270     brouard  7796:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7797:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7798:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7799:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7800:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7801:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7802:                      iyearc,iagec,offbyear,                            \
                   7803:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7804: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7805:            }else{
                   7806:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7807:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7808:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7809:            }
                   7810:          } /* end if covariate */
                   7811:        } /* nlstate */
                   7812:        fprintf(ficgp,"\nset out; unset label;\n");
                   7813:       } /* end cpt state*/
                   7814:     } /* end covariate */
                   7815:   } /* End if backcast */
                   7816:   
1.227     brouard  7817:   
1.238     brouard  7818:   /* 9eme writing MLE parameters */
                   7819:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7820:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7821:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7822:     for(k=1; k <=(nlstate+ndeath); k++){
                   7823:       if (k != i) {
1.227     brouard  7824:        fprintf(ficgp,"#   current state %d\n",k);
                   7825:        for(j=1; j <=ncovmodel; j++){
                   7826:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7827:          jk++; 
                   7828:        }
                   7829:        fprintf(ficgp,"\n");
1.126     brouard  7830:       }
                   7831:     }
1.223     brouard  7832:   }
1.187     brouard  7833:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7834:   
1.145     brouard  7835:   /*goto avoid;*/
1.238     brouard  7836:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7837:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7838:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7839:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7840:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7841:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7842:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7843:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7844:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7845:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7846:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7847:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7848:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7849:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7850:   fprintf(ficgp,"#\n");
1.223     brouard  7851:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7852:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7853:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7854:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7855:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7856:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7857:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7858:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7859:        continue;
1.264     brouard  7860:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7861:       strcpy(gplotlabel,"(");
1.276     brouard  7862:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7863:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7864:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7865:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7866:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7867:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7868:        vlv= nbcode[Tvaraff[k]][lv];
                   7869:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7870:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7871:       }
1.237     brouard  7872:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7873:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7874:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7875:       }        
1.264     brouard  7876:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7877:       fprintf(ficgp,"\n#\n");
1.264     brouard  7878:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7879:       fprintf(ficgp,"\nset key outside ");
                   7880:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7881:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7882:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7883:       if (ng==1){
                   7884:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7885:        fprintf(ficgp,"\nunset log y");
                   7886:       }else if (ng==2){
                   7887:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7888:        fprintf(ficgp,"\nset log y");
                   7889:       }else if (ng==3){
                   7890:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7891:        fprintf(ficgp,"\nset log y");
                   7892:       }else
                   7893:        fprintf(ficgp,"\nunset title ");
                   7894:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7895:       i=1;
                   7896:       for(k2=1; k2<=nlstate; k2++) {
                   7897:        k3=i;
                   7898:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7899:          if (k != k2){
                   7900:            switch( ng) {
                   7901:            case 1:
                   7902:              if(nagesqr==0)
                   7903:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7904:              else /* nagesqr =1 */
                   7905:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7906:              break;
                   7907:            case 2: /* ng=2 */
                   7908:              if(nagesqr==0)
                   7909:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7910:              else /* nagesqr =1 */
                   7911:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7912:              break;
                   7913:            case 3:
                   7914:              if(nagesqr==0)
                   7915:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7916:              else /* nagesqr =1 */
                   7917:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7918:              break;
                   7919:            }
                   7920:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7921:            ijp=1; /* product no age */
                   7922:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7923:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7924:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7925:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7926:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7927:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7928:                    if(DummyV[j]==0){
                   7929:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7930:                    }else{ /* quantitative */
                   7931:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7932:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7933:                    }
                   7934:                    ij++;
1.237     brouard  7935:                  }
1.268     brouard  7936:                } 
                   7937:              }else if(cptcovprod >0){
                   7938:                if(j==Tprod[ijp]) { /* */ 
                   7939:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7940:                  if(ijp <=cptcovprod) { /* Product */
                   7941:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7942:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7943:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7944:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7945:                      }else{ /* Vn is dummy and Vm is quanti */
                   7946:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7947:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7948:                      }
                   7949:                    }else{ /* Vn*Vm Vn is quanti */
                   7950:                      if(DummyV[Tvard[ijp][2]]==0){
                   7951:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7952:                      }else{ /* Both quanti */
                   7953:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7954:                      }
1.237     brouard  7955:                    }
1.268     brouard  7956:                    ijp++;
1.237     brouard  7957:                  }
1.268     brouard  7958:                } /* end Tprod */
1.237     brouard  7959:              } else{  /* simple covariate */
1.264     brouard  7960:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7961:                if(Dummy[j]==0){
                   7962:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7963:                }else{ /* quantitative */
                   7964:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7965:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7966:                }
1.237     brouard  7967:              } /* end simple */
                   7968:            } /* end j */
1.223     brouard  7969:          }else{
                   7970:            i=i-ncovmodel;
                   7971:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7972:              fprintf(ficgp," (1.");
                   7973:          }
1.227     brouard  7974:          
1.223     brouard  7975:          if(ng != 1){
                   7976:            fprintf(ficgp,")/(1");
1.227     brouard  7977:            
1.264     brouard  7978:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7979:              if(nagesqr==0)
1.264     brouard  7980:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7981:              else /* nagesqr =1 */
1.264     brouard  7982:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7983:               
1.223     brouard  7984:              ij=1;
                   7985:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7986:                 if(cptcovage >0){ 
                   7987:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7988:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7989:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7990:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7991:                       ij++;
                   7992:                     }
                   7993:                   }
                   7994:                 }else
                   7995:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7996:              }
                   7997:              fprintf(ficgp,")");
                   7998:            }
                   7999:            fprintf(ficgp,")");
                   8000:            if(ng ==2)
1.276     brouard  8001:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8002:            else /* ng= 3 */
1.276     brouard  8003:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8004:          }else{ /* end ng <> 1 */
                   8005:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8006:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8007:          }
                   8008:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8009:            fprintf(ficgp,",");
                   8010:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8011:            fprintf(ficgp,",");
                   8012:          i=i+ncovmodel;
                   8013:        } /* end k */
                   8014:       } /* end k2 */
1.276     brouard  8015:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8016:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8017:     } /* end k1 */
1.223     brouard  8018:   } /* end ng */
                   8019:   /* avoid: */
                   8020:   fflush(ficgp); 
1.126     brouard  8021: }  /* end gnuplot */
                   8022: 
                   8023: 
                   8024: /*************** Moving average **************/
1.219     brouard  8025: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8026:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8027:    
1.222     brouard  8028:    int i, cpt, cptcod;
                   8029:    int modcovmax =1;
                   8030:    int mobilavrange, mob;
                   8031:    int iage=0;
                   8032: 
1.266     brouard  8033:    double sum=0., sumr=0.;
1.222     brouard  8034:    double age;
1.266     brouard  8035:    double *sumnewp, *sumnewm, *sumnewmr;
                   8036:    double *agemingood, *agemaxgood; 
                   8037:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8038:   
                   8039:   
1.278     brouard  8040:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8041:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8042: 
                   8043:    sumnewp = vector(1,ncovcombmax);
                   8044:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8045:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8046:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8047:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8048:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8049:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8050: 
                   8051:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8052:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8053:      sumnewp[cptcod]=0.;
1.266     brouard  8054:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8055:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8056:    }
                   8057:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8058:   
1.266     brouard  8059:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8060:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8061:      else mobilavrange=mobilav;
                   8062:      for (age=bage; age<=fage; age++)
                   8063:        for (i=1; i<=nlstate;i++)
                   8064:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8065:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8066:      /* We keep the original values on the extreme ages bage, fage and for 
                   8067:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8068:        we use a 5 terms etc. until the borders are no more concerned. 
                   8069:      */ 
                   8070:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8071:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8072:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8073:           sumnewm[cptcod]=0.;
                   8074:           for (i=1; i<=nlstate;i++){
1.222     brouard  8075:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8076:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8077:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8078:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8079:             }
                   8080:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8081:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8082:           } /* end i */
                   8083:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8084:         } /* end cptcod */
1.222     brouard  8085:        }/* end age */
                   8086:      }/* end mob */
1.266     brouard  8087:    }else{
                   8088:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8089:      return -1;
1.266     brouard  8090:    }
                   8091: 
                   8092:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8093:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8094:      if(invalidvarcomb[cptcod]){
                   8095:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8096:        continue;
                   8097:      }
1.219     brouard  8098: 
1.266     brouard  8099:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8100:        sumnewm[cptcod]=0.;
                   8101:        sumnewmr[cptcod]=0.;
                   8102:        for (i=1; i<=nlstate;i++){
                   8103:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8104:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8105:        }
                   8106:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8107:         agemingoodr[cptcod]=age;
                   8108:        }
                   8109:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8110:           agemingood[cptcod]=age;
                   8111:        }
                   8112:      } /* age */
                   8113:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8114:        sumnewm[cptcod]=0.;
1.266     brouard  8115:        sumnewmr[cptcod]=0.;
1.222     brouard  8116:        for (i=1; i<=nlstate;i++){
                   8117:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8118:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8119:        }
                   8120:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8121:         agemaxgoodr[cptcod]=age;
1.222     brouard  8122:        }
                   8123:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8124:         agemaxgood[cptcod]=age;
                   8125:        }
                   8126:      } /* age */
                   8127:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8128:      /* but they will change */
                   8129:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8130:        sumnewm[cptcod]=0.;
                   8131:        sumnewmr[cptcod]=0.;
                   8132:        for (i=1; i<=nlstate;i++){
                   8133:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8134:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8135:        }
                   8136:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8137:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8138:           agemaxgoodr[cptcod]=age;  /* age min */
                   8139:           for (i=1; i<=nlstate;i++)
                   8140:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8141:         }else{ /* bad we change the value with the values of good ages */
                   8142:           for (i=1; i<=nlstate;i++){
                   8143:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8144:           } /* i */
                   8145:         } /* end bad */
                   8146:        }else{
                   8147:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8148:           agemaxgood[cptcod]=age;
                   8149:         }else{ /* bad we change the value with the values of good ages */
                   8150:           for (i=1; i<=nlstate;i++){
                   8151:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8152:           } /* i */
                   8153:         } /* end bad */
                   8154:        }/* end else */
                   8155:        sum=0.;sumr=0.;
                   8156:        for (i=1; i<=nlstate;i++){
                   8157:         sum+=mobaverage[(int)age][i][cptcod];
                   8158:         sumr+=probs[(int)age][i][cptcod];
                   8159:        }
                   8160:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8161:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8162:        } /* end bad */
                   8163:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8164:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8165:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8166:        } /* end bad */
                   8167:      }/* age */
1.266     brouard  8168: 
                   8169:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8170:        sumnewm[cptcod]=0.;
1.266     brouard  8171:        sumnewmr[cptcod]=0.;
1.222     brouard  8172:        for (i=1; i<=nlstate;i++){
                   8173:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8174:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8175:        } 
                   8176:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8177:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8178:           agemingoodr[cptcod]=age;
                   8179:           for (i=1; i<=nlstate;i++)
                   8180:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8181:         }else{ /* bad we change the value with the values of good ages */
                   8182:           for (i=1; i<=nlstate;i++){
                   8183:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8184:           } /* i */
                   8185:         } /* end bad */
                   8186:        }else{
                   8187:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8188:           agemingood[cptcod]=age;
                   8189:         }else{ /* bad */
                   8190:           for (i=1; i<=nlstate;i++){
                   8191:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8192:           } /* i */
                   8193:         } /* end bad */
                   8194:        }/* end else */
                   8195:        sum=0.;sumr=0.;
                   8196:        for (i=1; i<=nlstate;i++){
                   8197:         sum+=mobaverage[(int)age][i][cptcod];
                   8198:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8199:        }
1.266     brouard  8200:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8201:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8202:        } /* end bad */
                   8203:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8204:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8205:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8206:        } /* end bad */
                   8207:      }/* age */
1.266     brouard  8208: 
1.222     brouard  8209:                
                   8210:      for (age=bage; age<=fage; age++){
1.235     brouard  8211:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8212:        sumnewp[cptcod]=0.;
                   8213:        sumnewm[cptcod]=0.;
                   8214:        for (i=1; i<=nlstate;i++){
                   8215:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8216:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8217:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8218:        }
                   8219:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8220:      }
                   8221:      /* printf("\n"); */
                   8222:      /* } */
1.266     brouard  8223: 
1.222     brouard  8224:      /* brutal averaging */
1.266     brouard  8225:      /* for (i=1; i<=nlstate;i++){ */
                   8226:      /*   for (age=1; age<=bage; age++){ */
                   8227:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8228:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8229:      /*   }     */
                   8230:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8231:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8232:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8233:      /*   } */
                   8234:      /* } /\* end i status *\/ */
                   8235:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8236:      /*   for (age=1; age<=AGESUP; age++){ */
                   8237:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8238:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8239:      /*   } */
                   8240:      /* } */
1.222     brouard  8241:    }/* end cptcod */
1.266     brouard  8242:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8243:    free_vector(agemaxgood,1, ncovcombmax);
                   8244:    free_vector(agemingood,1, ncovcombmax);
                   8245:    free_vector(agemingoodr,1, ncovcombmax);
                   8246:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8247:    free_vector(sumnewm,1, ncovcombmax);
                   8248:    free_vector(sumnewp,1, ncovcombmax);
                   8249:    return 0;
                   8250:  }/* End movingaverage */
1.218     brouard  8251:  
1.126     brouard  8252: 
                   8253: /************** Forecasting ******************/
1.269     brouard  8254:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8255:   /* proj1, year, month, day of starting projection 
                   8256:      agemin, agemax range of age
                   8257:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8258:      anproj2 year of en of projection (same day and month as proj1).
                   8259:   */
1.267     brouard  8260:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8261:   double agec; /* generic age */
                   8262:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8263:   double *popeffectif,*popcount;
                   8264:   double ***p3mat;
1.218     brouard  8265:   /* double ***mobaverage; */
1.126     brouard  8266:   char fileresf[FILENAMELENGTH];
                   8267: 
                   8268:   agelim=AGESUP;
1.211     brouard  8269:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8270:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8271:      We still use firstpass and lastpass as another selection.
                   8272:   */
1.214     brouard  8273:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8274:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8275:  
1.201     brouard  8276:   strcpy(fileresf,"F_"); 
                   8277:   strcat(fileresf,fileresu);
1.126     brouard  8278:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8279:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8280:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8281:   }
1.235     brouard  8282:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8283:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8284: 
1.225     brouard  8285:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8286: 
                   8287: 
                   8288:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8289:   if (stepm<=12) stepsize=1;
                   8290:   if(estepm < stepm){
                   8291:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8292:   }
1.270     brouard  8293:   else{
                   8294:     hstepm=estepm;   
                   8295:   }
                   8296:   if(estepm > stepm){ /* Yes every two year */
                   8297:     stepsize=2;
                   8298:   }
1.126     brouard  8299: 
                   8300:   hstepm=hstepm/stepm; 
                   8301:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8302:                                fractional in yp1 */
                   8303:   anprojmean=yp;
                   8304:   yp2=modf((yp1*12),&yp);
                   8305:   mprojmean=yp;
                   8306:   yp1=modf((yp2*30.5),&yp);
                   8307:   jprojmean=yp;
                   8308:   if(jprojmean==0) jprojmean=1;
                   8309:   if(mprojmean==0) jprojmean=1;
                   8310: 
1.227     brouard  8311:   i1=pow(2,cptcoveff);
1.126     brouard  8312:   if (cptcovn < 1){i1=1;}
                   8313:   
                   8314:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8315:   
                   8316:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8317:   
1.126     brouard  8318: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8319:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8320:   for(k=1; k<=i1;k++){
1.253     brouard  8321:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8322:       continue;
1.227     brouard  8323:     if(invalidvarcomb[k]){
                   8324:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8325:       continue;
                   8326:     }
                   8327:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8328:     for(j=1;j<=cptcoveff;j++) {
                   8329:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8330:     }
1.235     brouard  8331:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8332:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8333:     }
1.227     brouard  8334:     fprintf(ficresf," yearproj age");
                   8335:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8336:       for(i=1; i<=nlstate;i++)               
                   8337:        fprintf(ficresf," p%d%d",i,j);
                   8338:       fprintf(ficresf," wp.%d",j);
                   8339:     }
                   8340:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8341:       fprintf(ficresf,"\n");
                   8342:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8343:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8344:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8345:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8346:        nhstepm = nhstepm/hstepm; 
                   8347:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8348:        oldm=oldms;savm=savms;
1.268     brouard  8349:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8350:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8351:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8352:        for (h=0; h<=nhstepm; h++){
                   8353:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8354:            break;
                   8355:          }
                   8356:        }
                   8357:        fprintf(ficresf,"\n");
                   8358:        for(j=1;j<=cptcoveff;j++) 
                   8359:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8360:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8361:        
                   8362:        for(j=1; j<=nlstate+ndeath;j++) {
                   8363:          ppij=0.;
                   8364:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8365:            if (mobilav>=1)
                   8366:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8367:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8368:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8369:            }
1.268     brouard  8370:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8371:          } /* end i */
                   8372:          fprintf(ficresf," %.3f", ppij);
                   8373:        }/* end j */
1.227     brouard  8374:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8375:       } /* end agec */
1.266     brouard  8376:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8377:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8378:     } /* end yearp */
                   8379:   } /* end  k */
1.219     brouard  8380:        
1.126     brouard  8381:   fclose(ficresf);
1.215     brouard  8382:   printf("End of Computing forecasting \n");
                   8383:   fprintf(ficlog,"End of Computing forecasting\n");
                   8384: 
1.126     brouard  8385: }
                   8386: 
1.269     brouard  8387: /************** Back Forecasting ******************/
                   8388:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8389:   /* back1, year, month, day of starting backection
                   8390:      agemin, agemax range of age
                   8391:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8392:      anback2 year of end of backprojection (same day and month as back1).
                   8393:      prevacurrent and prev are prevalences.
1.267     brouard  8394:   */
                   8395:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8396:   double agec; /* generic age */
1.268     brouard  8397:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8398:   double *popeffectif,*popcount;
                   8399:   double ***p3mat;
                   8400:   /* double ***mobaverage; */
                   8401:   char fileresfb[FILENAMELENGTH];
                   8402:  
1.268     brouard  8403:   agelim=AGEINF;
1.267     brouard  8404:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8405:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8406:      We still use firstpass and lastpass as another selection.
                   8407:   */
                   8408:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8409:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8410: 
                   8411:   /*Do we need to compute prevalence again?*/
                   8412: 
                   8413:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8414:   
                   8415:   strcpy(fileresfb,"FB_");
                   8416:   strcat(fileresfb,fileresu);
                   8417:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8418:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8419:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8420:   }
                   8421:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8422:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8423:   
                   8424:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8425:   
                   8426:    
                   8427:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8428:   if (stepm<=12) stepsize=1;
                   8429:   if(estepm < stepm){
                   8430:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8431:   }
1.270     brouard  8432:   else{
                   8433:     hstepm=estepm;   
                   8434:   }
                   8435:   if(estepm >= stepm){ /* Yes every two year */
                   8436:     stepsize=2;
                   8437:   }
1.267     brouard  8438:   
                   8439:   hstepm=hstepm/stepm;
                   8440:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8441:                                fractional in yp1 */
                   8442:   anprojmean=yp;
                   8443:   yp2=modf((yp1*12),&yp);
                   8444:   mprojmean=yp;
                   8445:   yp1=modf((yp2*30.5),&yp);
                   8446:   jprojmean=yp;
                   8447:   if(jprojmean==0) jprojmean=1;
                   8448:   if(mprojmean==0) jprojmean=1;
                   8449:   
                   8450:   i1=pow(2,cptcoveff);
                   8451:   if (cptcovn < 1){i1=1;}
                   8452:   
                   8453:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8454:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8455:   
                   8456:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8457:   
                   8458:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8459:   for(k=1; k<=i1;k++){
                   8460:     if(i1 != 1 && TKresult[nres]!= k)
                   8461:       continue;
                   8462:     if(invalidvarcomb[k]){
                   8463:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8464:       continue;
                   8465:     }
1.268     brouard  8466:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8467:     for(j=1;j<=cptcoveff;j++) {
                   8468:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8469:     }
                   8470:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8471:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8472:     }
                   8473:     fprintf(ficresfb," yearbproj age");
                   8474:     for(j=1; j<=nlstate+ndeath;j++){
                   8475:       for(i=1; i<=nlstate;i++)
1.268     brouard  8476:        fprintf(ficresfb," b%d%d",i,j);
                   8477:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8478:     }
                   8479:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8480:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8481:       fprintf(ficresfb,"\n");
                   8482:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8483:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8484:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8485:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8486:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8487:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8488:        nhstepm = nhstepm/hstepm;
                   8489:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8490:        oldm=oldms;savm=savms;
1.268     brouard  8491:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8492:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8493:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8494:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8495:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8496:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8497:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8498:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8499:            break;
                   8500:          }
                   8501:        }
                   8502:        fprintf(ficresfb,"\n");
                   8503:        for(j=1;j<=cptcoveff;j++)
                   8504:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8505:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8506:        for(i=1; i<=nlstate+ndeath;i++) {
                   8507:          ppij=0.;ppi=0.;
                   8508:          for(j=1; j<=nlstate;j++) {
                   8509:            /* if (mobilav==1) */
1.269     brouard  8510:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8511:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8512:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8513:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8514:              /* else { */
                   8515:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8516:              /* } */
1.268     brouard  8517:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8518:          } /* end j */
                   8519:          if(ppi <0.99){
                   8520:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8521:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8522:          }
                   8523:          fprintf(ficresfb," %.3f", ppij);
                   8524:        }/* end j */
1.267     brouard  8525:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8526:       } /* end agec */
                   8527:     } /* end yearp */
                   8528:   } /* end k */
1.217     brouard  8529:   
1.267     brouard  8530:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8531:   
1.267     brouard  8532:   fclose(ficresfb);
                   8533:   printf("End of Computing Back forecasting \n");
                   8534:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8535:        
1.267     brouard  8536: }
1.217     brouard  8537: 
1.269     brouard  8538: /* Variance of prevalence limit: varprlim */
                   8539:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8540:     /*------- Variance of period (stable) prevalence------*/   
                   8541:  
                   8542:    char fileresvpl[FILENAMELENGTH];  
                   8543:    FILE *ficresvpl;
                   8544:    double **oldm, **savm;
                   8545:    double **varpl; /* Variances of prevalence limits by age */   
                   8546:    int i1, k, nres, j ;
                   8547:    
                   8548:     strcpy(fileresvpl,"VPL_");
                   8549:     strcat(fileresvpl,fileresu);
                   8550:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8551:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8552:       exit(0);
                   8553:     }
                   8554:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8555:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8556:     
                   8557:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8558:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8559:     
                   8560:     i1=pow(2,cptcoveff);
                   8561:     if (cptcovn < 1){i1=1;}
                   8562: 
                   8563:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8564:     for(k=1; k<=i1;k++){
                   8565:       if(i1 != 1 && TKresult[nres]!= k)
                   8566:        continue;
                   8567:       fprintf(ficresvpl,"\n#****** ");
                   8568:       printf("\n#****** ");
                   8569:       fprintf(ficlog,"\n#****** ");
                   8570:       for(j=1;j<=cptcoveff;j++) {
                   8571:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8572:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8573:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8574:       }
                   8575:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8576:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8577:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8578:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8579:       }        
                   8580:       fprintf(ficresvpl,"******\n");
                   8581:       printf("******\n");
                   8582:       fprintf(ficlog,"******\n");
                   8583:       
                   8584:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8585:       oldm=oldms;savm=savms;
                   8586:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8587:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8588:       /*}*/
                   8589:     }
                   8590:     
                   8591:     fclose(ficresvpl);
                   8592:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8593:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8594: 
                   8595:  }
                   8596: /* Variance of back prevalence: varbprlim */
                   8597:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8598:       /*------- Variance of back (stable) prevalence------*/
                   8599: 
                   8600:    char fileresvbl[FILENAMELENGTH];  
                   8601:    FILE  *ficresvbl;
                   8602: 
                   8603:    double **oldm, **savm;
                   8604:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8605:    int i1, k, nres, j ;
                   8606: 
                   8607:    strcpy(fileresvbl,"VBL_");
                   8608:    strcat(fileresvbl,fileresu);
                   8609:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8610:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8611:      exit(0);
                   8612:    }
                   8613:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8614:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8615:    
                   8616:    
                   8617:    i1=pow(2,cptcoveff);
                   8618:    if (cptcovn < 1){i1=1;}
                   8619:    
                   8620:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8621:      for(k=1; k<=i1;k++){
                   8622:        if(i1 != 1 && TKresult[nres]!= k)
                   8623:         continue;
                   8624:        fprintf(ficresvbl,"\n#****** ");
                   8625:        printf("\n#****** ");
                   8626:        fprintf(ficlog,"\n#****** ");
                   8627:        for(j=1;j<=cptcoveff;j++) {
                   8628:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8629:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8630:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8631:        }
                   8632:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8633:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8634:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8635:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8636:        }
                   8637:        fprintf(ficresvbl,"******\n");
                   8638:        printf("******\n");
                   8639:        fprintf(ficlog,"******\n");
                   8640:        
                   8641:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8642:        oldm=oldms;savm=savms;
                   8643:        
                   8644:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8645:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8646:        /*}*/
                   8647:      }
                   8648:    
                   8649:    fclose(ficresvbl);
                   8650:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8651:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8652: 
                   8653:  } /* End of varbprlim */
                   8654: 
1.126     brouard  8655: /************** Forecasting *****not tested NB*************/
1.227     brouard  8656: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8657:   
1.227     brouard  8658: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8659: /*   int *popage; */
                   8660: /*   double calagedatem, agelim, kk1, kk2; */
                   8661: /*   double *popeffectif,*popcount; */
                   8662: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8663: /*   /\* double ***mobaverage; *\/ */
                   8664: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8665: 
1.227     brouard  8666: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8667: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8668: /*   agelim=AGESUP; */
                   8669: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8670:   
1.227     brouard  8671: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8672:   
                   8673:   
1.227     brouard  8674: /*   strcpy(filerespop,"POP_");  */
                   8675: /*   strcat(filerespop,fileresu); */
                   8676: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8677: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8678: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8679: /*   } */
                   8680: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8681: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8682: 
1.227     brouard  8683: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8684: 
1.227     brouard  8685: /*   /\* if (mobilav!=0) { *\/ */
                   8686: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8687: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8688: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8689: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8690: /*   /\*   } *\/ */
                   8691: /*   /\* } *\/ */
1.126     brouard  8692: 
1.227     brouard  8693: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8694: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8695:   
1.227     brouard  8696: /*   agelim=AGESUP; */
1.126     brouard  8697:   
1.227     brouard  8698: /*   hstepm=1; */
                   8699: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8700:        
1.227     brouard  8701: /*   if (popforecast==1) { */
                   8702: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8703: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8704: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8705: /*     }  */
                   8706: /*     popage=ivector(0,AGESUP); */
                   8707: /*     popeffectif=vector(0,AGESUP); */
                   8708: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8709:     
1.227     brouard  8710: /*     i=1;    */
                   8711: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8712:     
1.227     brouard  8713: /*     imx=i; */
                   8714: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8715: /*   } */
1.218     brouard  8716:   
1.227     brouard  8717: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8718: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8719: /*       k=k+1; */
                   8720: /*       fprintf(ficrespop,"\n#******"); */
                   8721: /*       for(j=1;j<=cptcoveff;j++) { */
                   8722: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8723: /*       } */
                   8724: /*       fprintf(ficrespop,"******\n"); */
                   8725: /*       fprintf(ficrespop,"# Age"); */
                   8726: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8727: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8728:       
1.227     brouard  8729: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8730: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8731:        
1.227     brouard  8732: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8733: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8734: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8735:          
1.227     brouard  8736: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8737: /*       oldm=oldms;savm=savms; */
                   8738: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8739:          
1.227     brouard  8740: /*       for (h=0; h<=nhstepm; h++){ */
                   8741: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8742: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8743: /*         }  */
                   8744: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8745: /*           kk1=0.;kk2=0; */
                   8746: /*           for(i=1; i<=nlstate;i++) {               */
                   8747: /*             if (mobilav==1)  */
                   8748: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8749: /*             else { */
                   8750: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8751: /*             } */
                   8752: /*           } */
                   8753: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8754: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8755: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8756: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8757: /*           } */
                   8758: /*         } */
                   8759: /*         for(i=1; i<=nlstate;i++){ */
                   8760: /*           kk1=0.; */
                   8761: /*           for(j=1; j<=nlstate;j++){ */
                   8762: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8763: /*           } */
                   8764: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8765: /*         } */
1.218     brouard  8766:            
1.227     brouard  8767: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8768: /*           for(j=1; j<=nlstate;j++)  */
                   8769: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8770: /*       } */
                   8771: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8772: /*     } */
                   8773: /*       } */
1.218     brouard  8774:       
1.227     brouard  8775: /*       /\******\/ */
1.218     brouard  8776:       
1.227     brouard  8777: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8778: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8779: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8780: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8781: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8782:          
1.227     brouard  8783: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8784: /*       oldm=oldms;savm=savms; */
                   8785: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8786: /*       for (h=0; h<=nhstepm; h++){ */
                   8787: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8788: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8789: /*         }  */
                   8790: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8791: /*           kk1=0.;kk2=0; */
                   8792: /*           for(i=1; i<=nlstate;i++) {               */
                   8793: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8794: /*           } */
                   8795: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8796: /*         } */
                   8797: /*       } */
                   8798: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8799: /*     } */
                   8800: /*       } */
                   8801: /*     }  */
                   8802: /*   } */
1.218     brouard  8803:   
1.227     brouard  8804: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8805:   
1.227     brouard  8806: /*   if (popforecast==1) { */
                   8807: /*     free_ivector(popage,0,AGESUP); */
                   8808: /*     free_vector(popeffectif,0,AGESUP); */
                   8809: /*     free_vector(popcount,0,AGESUP); */
                   8810: /*   } */
                   8811: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8812: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8813: /*   fclose(ficrespop); */
                   8814: /* } /\* End of popforecast *\/ */
1.218     brouard  8815:  
1.126     brouard  8816: int fileappend(FILE *fichier, char *optionfich)
                   8817: {
                   8818:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8819:     printf("Problem with file: %s\n", optionfich);
                   8820:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8821:     return (0);
                   8822:   }
                   8823:   fflush(fichier);
                   8824:   return (1);
                   8825: }
                   8826: 
                   8827: 
                   8828: /**************** function prwizard **********************/
                   8829: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8830: {
                   8831: 
                   8832:   /* Wizard to print covariance matrix template */
                   8833: 
1.164     brouard  8834:   char ca[32], cb[32];
                   8835:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8836:   int numlinepar;
                   8837: 
                   8838:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8839:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8840:   for(i=1; i <=nlstate; i++){
                   8841:     jj=0;
                   8842:     for(j=1; j <=nlstate+ndeath; j++){
                   8843:       if(j==i) continue;
                   8844:       jj++;
                   8845:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8846:       printf("%1d%1d",i,j);
                   8847:       fprintf(ficparo,"%1d%1d",i,j);
                   8848:       for(k=1; k<=ncovmodel;k++){
                   8849:        /*        printf(" %lf",param[i][j][k]); */
                   8850:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8851:        printf(" 0.");
                   8852:        fprintf(ficparo," 0.");
                   8853:       }
                   8854:       printf("\n");
                   8855:       fprintf(ficparo,"\n");
                   8856:     }
                   8857:   }
                   8858:   printf("# Scales (for hessian or gradient estimation)\n");
                   8859:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8860:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8861:   for(i=1; i <=nlstate; i++){
                   8862:     jj=0;
                   8863:     for(j=1; j <=nlstate+ndeath; j++){
                   8864:       if(j==i) continue;
                   8865:       jj++;
                   8866:       fprintf(ficparo,"%1d%1d",i,j);
                   8867:       printf("%1d%1d",i,j);
                   8868:       fflush(stdout);
                   8869:       for(k=1; k<=ncovmodel;k++){
                   8870:        /*      printf(" %le",delti3[i][j][k]); */
                   8871:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8872:        printf(" 0.");
                   8873:        fprintf(ficparo," 0.");
                   8874:       }
                   8875:       numlinepar++;
                   8876:       printf("\n");
                   8877:       fprintf(ficparo,"\n");
                   8878:     }
                   8879:   }
                   8880:   printf("# Covariance matrix\n");
                   8881: /* # 121 Var(a12)\n\ */
                   8882: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8883: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8884: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8885: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8886: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8887: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8888: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8889:   fflush(stdout);
                   8890:   fprintf(ficparo,"# Covariance matrix\n");
                   8891:   /* # 121 Var(a12)\n\ */
                   8892:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8893:   /* #   ...\n\ */
                   8894:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8895:   
                   8896:   for(itimes=1;itimes<=2;itimes++){
                   8897:     jj=0;
                   8898:     for(i=1; i <=nlstate; i++){
                   8899:       for(j=1; j <=nlstate+ndeath; j++){
                   8900:        if(j==i) continue;
                   8901:        for(k=1; k<=ncovmodel;k++){
                   8902:          jj++;
                   8903:          ca[0]= k+'a'-1;ca[1]='\0';
                   8904:          if(itimes==1){
                   8905:            printf("#%1d%1d%d",i,j,k);
                   8906:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8907:          }else{
                   8908:            printf("%1d%1d%d",i,j,k);
                   8909:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8910:            /*  printf(" %.5le",matcov[i][j]); */
                   8911:          }
                   8912:          ll=0;
                   8913:          for(li=1;li <=nlstate; li++){
                   8914:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8915:              if(lj==li) continue;
                   8916:              for(lk=1;lk<=ncovmodel;lk++){
                   8917:                ll++;
                   8918:                if(ll<=jj){
                   8919:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8920:                  if(ll<jj){
                   8921:                    if(itimes==1){
                   8922:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8923:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8924:                    }else{
                   8925:                      printf(" 0.");
                   8926:                      fprintf(ficparo," 0.");
                   8927:                    }
                   8928:                  }else{
                   8929:                    if(itimes==1){
                   8930:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8931:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8932:                    }else{
                   8933:                      printf(" 0.");
                   8934:                      fprintf(ficparo," 0.");
                   8935:                    }
                   8936:                  }
                   8937:                }
                   8938:              } /* end lk */
                   8939:            } /* end lj */
                   8940:          } /* end li */
                   8941:          printf("\n");
                   8942:          fprintf(ficparo,"\n");
                   8943:          numlinepar++;
                   8944:        } /* end k*/
                   8945:       } /*end j */
                   8946:     } /* end i */
                   8947:   } /* end itimes */
                   8948: 
                   8949: } /* end of prwizard */
                   8950: /******************* Gompertz Likelihood ******************************/
                   8951: double gompertz(double x[])
                   8952: { 
                   8953:   double A,B,L=0.0,sump=0.,num=0.;
                   8954:   int i,n=0; /* n is the size of the sample */
                   8955: 
1.220     brouard  8956:   for (i=1;i<=imx ; i++) {
1.126     brouard  8957:     sump=sump+weight[i];
                   8958:     /*    sump=sump+1;*/
                   8959:     num=num+1;
                   8960:   }
                   8961:  
                   8962:  
                   8963:   /* for (i=0; i<=imx; i++) 
                   8964:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8965: 
                   8966:   for (i=1;i<=imx ; i++)
                   8967:     {
                   8968:       if (cens[i] == 1 && wav[i]>1)
                   8969:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8970:       
                   8971:       if (cens[i] == 0 && wav[i]>1)
                   8972:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8973:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8974:       
                   8975:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8976:       if (wav[i] > 1 ) { /* ??? */
                   8977:        L=L+A*weight[i];
                   8978:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8979:       }
                   8980:     }
                   8981: 
                   8982:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8983:  
                   8984:   return -2*L*num/sump;
                   8985: }
                   8986: 
1.136     brouard  8987: #ifdef GSL
                   8988: /******************* Gompertz_f Likelihood ******************************/
                   8989: double gompertz_f(const gsl_vector *v, void *params)
                   8990: { 
                   8991:   double A,B,LL=0.0,sump=0.,num=0.;
                   8992:   double *x= (double *) v->data;
                   8993:   int i,n=0; /* n is the size of the sample */
                   8994: 
                   8995:   for (i=0;i<=imx-1 ; i++) {
                   8996:     sump=sump+weight[i];
                   8997:     /*    sump=sump+1;*/
                   8998:     num=num+1;
                   8999:   }
                   9000:  
                   9001:  
                   9002:   /* for (i=0; i<=imx; i++) 
                   9003:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9004:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9005:   for (i=1;i<=imx ; i++)
                   9006:     {
                   9007:       if (cens[i] == 1 && wav[i]>1)
                   9008:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9009:       
                   9010:       if (cens[i] == 0 && wav[i]>1)
                   9011:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9012:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9013:       
                   9014:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9015:       if (wav[i] > 1 ) { /* ??? */
                   9016:        LL=LL+A*weight[i];
                   9017:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9018:       }
                   9019:     }
                   9020: 
                   9021:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9022:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9023:  
                   9024:   return -2*LL*num/sump;
                   9025: }
                   9026: #endif
                   9027: 
1.126     brouard  9028: /******************* Printing html file ***********/
1.201     brouard  9029: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9030:                  int lastpass, int stepm, int weightopt, char model[],\
                   9031:                  int imx,  double p[],double **matcov,double agemortsup){
                   9032:   int i,k;
                   9033: 
                   9034:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9035:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9036:   for (i=1;i<=2;i++) 
                   9037:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9038:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9039:   fprintf(fichtm,"</ul>");
                   9040: 
                   9041: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9042: 
                   9043:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9044: 
                   9045:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9046:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9047: 
                   9048:  
                   9049:   fflush(fichtm);
                   9050: }
                   9051: 
                   9052: /******************* Gnuplot file **************/
1.201     brouard  9053: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9054: 
                   9055:   char dirfileres[132],optfileres[132];
1.164     brouard  9056: 
1.126     brouard  9057:   int ng;
                   9058: 
                   9059: 
                   9060:   /*#ifdef windows */
                   9061:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9062:     /*#endif */
                   9063: 
                   9064: 
                   9065:   strcpy(dirfileres,optionfilefiname);
                   9066:   strcpy(optfileres,"vpl");
1.199     brouard  9067:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9068:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9069:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9070:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9071:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9072: 
                   9073: } 
                   9074: 
1.136     brouard  9075: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9076: {
1.126     brouard  9077: 
1.136     brouard  9078:   /*-------- data file ----------*/
                   9079:   FILE *fic;
                   9080:   char dummy[]="                         ";
1.240     brouard  9081:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9082:   int lstra;
1.136     brouard  9083:   int linei, month, year,iout;
                   9084:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9085:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9086:   char *stratrunc;
1.223     brouard  9087: 
1.240     brouard  9088:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9089:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9090: 
1.240     brouard  9091:   for(v=1; v <=ncovcol;v++){
                   9092:     DummyV[v]=0;
                   9093:     FixedV[v]=0;
                   9094:   }
                   9095:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9096:     DummyV[v]=1;
                   9097:     FixedV[v]=0;
                   9098:   }
                   9099:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9100:     DummyV[v]=0;
                   9101:     FixedV[v]=1;
                   9102:   }
                   9103:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9104:     DummyV[v]=1;
                   9105:     FixedV[v]=1;
                   9106:   }
                   9107:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9108:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9109:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9110:   }
1.126     brouard  9111: 
1.136     brouard  9112:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9113:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9114:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9115:   }
1.126     brouard  9116: 
1.136     brouard  9117:   i=1;
                   9118:   linei=0;
                   9119:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9120:     linei=linei+1;
                   9121:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9122:       if(line[j] == '\t')
                   9123:        line[j] = ' ';
                   9124:     }
                   9125:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9126:       ;
                   9127:     };
                   9128:     line[j+1]=0;  /* Trims blanks at end of line */
                   9129:     if(line[0]=='#'){
                   9130:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9131:       printf("Comment line\n%s\n",line);
                   9132:       continue;
                   9133:     }
                   9134:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9135:     strcpy(line, linetmp);
1.223     brouard  9136:     
                   9137:     /* Loops on waves */
                   9138:     for (j=maxwav;j>=1;j--){
                   9139:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9140:        cutv(stra, strb, line, ' '); 
                   9141:        if(strb[0]=='.') { /* Missing value */
                   9142:          lval=-1;
                   9143:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9144:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9145:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9146:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9147:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9148:            return 1;
                   9149:          }
                   9150:        }else{
                   9151:          errno=0;
                   9152:          /* what_kind_of_number(strb); */
                   9153:          dval=strtod(strb,&endptr); 
                   9154:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9155:          /* if(strb != endptr && *endptr == '\0') */
                   9156:          /*    dval=dlval; */
                   9157:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9158:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9159:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9160:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9161:            return 1;
                   9162:          }
                   9163:          cotqvar[j][iv][i]=dval; 
                   9164:          cotvar[j][ntv+iv][i]=dval; 
                   9165:        }
                   9166:        strcpy(line,stra);
1.223     brouard  9167:       }/* end loop ntqv */
1.225     brouard  9168:       
1.223     brouard  9169:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9170:        cutv(stra, strb, line, ' '); 
                   9171:        if(strb[0]=='.') { /* Missing value */
                   9172:          lval=-1;
                   9173:        }else{
                   9174:          errno=0;
                   9175:          lval=strtol(strb,&endptr,10); 
                   9176:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9177:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9178:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9179:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9180:            return 1;
                   9181:          }
                   9182:        }
                   9183:        if(lval <-1 || lval >1){
                   9184:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9185:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9186:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9187:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9188:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9189:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9190:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9191:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9192:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9193:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9194:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9195:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9196:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9197:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9198:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9199:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9200:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9201:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9202:          return 1;
                   9203:        }
                   9204:        cotvar[j][iv][i]=(double)(lval);
                   9205:        strcpy(line,stra);
1.223     brouard  9206:       }/* end loop ntv */
1.225     brouard  9207:       
1.223     brouard  9208:       /* Statuses  at wave */
1.137     brouard  9209:       cutv(stra, strb, line, ' '); 
1.223     brouard  9210:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9211:        lval=-1;
1.136     brouard  9212:       }else{
1.238     brouard  9213:        errno=0;
                   9214:        lval=strtol(strb,&endptr,10); 
                   9215:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9216:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9217:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9218:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9219:          return 1;
                   9220:        }
1.136     brouard  9221:       }
1.225     brouard  9222:       
1.136     brouard  9223:       s[j][i]=lval;
1.225     brouard  9224:       
1.223     brouard  9225:       /* Date of Interview */
1.136     brouard  9226:       strcpy(line,stra);
                   9227:       cutv(stra, strb,line,' ');
1.169     brouard  9228:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9229:       }
1.169     brouard  9230:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9231:        month=99;
                   9232:        year=9999;
1.136     brouard  9233:       }else{
1.225     brouard  9234:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9235:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9236:        return 1;
1.136     brouard  9237:       }
                   9238:       anint[j][i]= (double) year; 
                   9239:       mint[j][i]= (double)month; 
                   9240:       strcpy(line,stra);
1.223     brouard  9241:     } /* End loop on waves */
1.225     brouard  9242:     
1.223     brouard  9243:     /* Date of death */
1.136     brouard  9244:     cutv(stra, strb,line,' '); 
1.169     brouard  9245:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9246:     }
1.169     brouard  9247:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9248:       month=99;
                   9249:       year=9999;
                   9250:     }else{
1.141     brouard  9251:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9252:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9253:       return 1;
1.136     brouard  9254:     }
                   9255:     andc[i]=(double) year; 
                   9256:     moisdc[i]=(double) month; 
                   9257:     strcpy(line,stra);
                   9258:     
1.223     brouard  9259:     /* Date of birth */
1.136     brouard  9260:     cutv(stra, strb,line,' '); 
1.169     brouard  9261:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9262:     }
1.169     brouard  9263:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9264:       month=99;
                   9265:       year=9999;
                   9266:     }else{
1.141     brouard  9267:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9268:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9269:       return 1;
1.136     brouard  9270:     }
                   9271:     if (year==9999) {
1.141     brouard  9272:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9273:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9274:       return 1;
                   9275:       
1.136     brouard  9276:     }
                   9277:     annais[i]=(double)(year);
                   9278:     moisnais[i]=(double)(month); 
                   9279:     strcpy(line,stra);
1.225     brouard  9280:     
1.223     brouard  9281:     /* Sample weight */
1.136     brouard  9282:     cutv(stra, strb,line,' '); 
                   9283:     errno=0;
                   9284:     dval=strtod(strb,&endptr); 
                   9285:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9286:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9287:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9288:       fflush(ficlog);
                   9289:       return 1;
                   9290:     }
                   9291:     weight[i]=dval; 
                   9292:     strcpy(line,stra);
1.225     brouard  9293:     
1.223     brouard  9294:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9295:       cutv(stra, strb, line, ' '); 
                   9296:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9297:        lval=-1;
1.223     brouard  9298:       }else{
1.225     brouard  9299:        errno=0;
                   9300:        /* what_kind_of_number(strb); */
                   9301:        dval=strtod(strb,&endptr);
                   9302:        /* if(strb != endptr && *endptr == '\0') */
                   9303:        /*   dval=dlval; */
                   9304:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9305:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9306:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9307:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9308:          return 1;
                   9309:        }
                   9310:        coqvar[iv][i]=dval; 
1.226     brouard  9311:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9312:       }
                   9313:       strcpy(line,stra);
                   9314:     }/* end loop nqv */
1.136     brouard  9315:     
1.223     brouard  9316:     /* Covariate values */
1.136     brouard  9317:     for (j=ncovcol;j>=1;j--){
                   9318:       cutv(stra, strb,line,' '); 
1.223     brouard  9319:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9320:        lval=-1;
1.136     brouard  9321:       }else{
1.225     brouard  9322:        errno=0;
                   9323:        lval=strtol(strb,&endptr,10); 
                   9324:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9325:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9326:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9327:          return 1;
                   9328:        }
1.136     brouard  9329:       }
                   9330:       if(lval <-1 || lval >1){
1.225     brouard  9331:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9332:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9333:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9334:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9335:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9336:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9337:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9338:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9339:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9340:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9341:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9342:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9343:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9344:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9345:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9346:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9347:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9348:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9349:        return 1;
1.136     brouard  9350:       }
                   9351:       covar[j][i]=(double)(lval);
                   9352:       strcpy(line,stra);
                   9353:     }  
                   9354:     lstra=strlen(stra);
1.225     brouard  9355:     
1.136     brouard  9356:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9357:       stratrunc = &(stra[lstra-9]);
                   9358:       num[i]=atol(stratrunc);
                   9359:     }
                   9360:     else
                   9361:       num[i]=atol(stra);
                   9362:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9363:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9364:     
                   9365:     i=i+1;
                   9366:   } /* End loop reading  data */
1.225     brouard  9367:   
1.136     brouard  9368:   *imax=i-1; /* Number of individuals */
                   9369:   fclose(fic);
1.225     brouard  9370:   
1.136     brouard  9371:   return (0);
1.164     brouard  9372:   /* endread: */
1.225     brouard  9373:   printf("Exiting readdata: ");
                   9374:   fclose(fic);
                   9375:   return (1);
1.223     brouard  9376: }
1.126     brouard  9377: 
1.234     brouard  9378: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9379:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9380:   while (*p2 == ' ')
1.234     brouard  9381:     p2++; 
                   9382:   /* while ((*p1++ = *p2++) !=0) */
                   9383:   /*   ; */
                   9384:   /* do */
                   9385:   /*   while (*p2 == ' ') */
                   9386:   /*     p2++; */
                   9387:   /* while (*p1++ == *p2++); */
                   9388:   *stri=p2; 
1.145     brouard  9389: }
                   9390: 
1.235     brouard  9391: int decoderesult ( char resultline[], int nres)
1.230     brouard  9392: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9393: {
1.235     brouard  9394:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9395:   char resultsav[MAXLINE];
1.234     brouard  9396:   int resultmodel[MAXLINE];
                   9397:   int modelresult[MAXLINE];
1.230     brouard  9398:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9399: 
1.234     brouard  9400:   removefirstspace(&resultline);
1.233     brouard  9401:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9402: 
                   9403:   if (strstr(resultline,"v") !=0){
                   9404:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9405:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9406:     return 1;
                   9407:   }
                   9408:   trimbb(resultsav, resultline);
                   9409:   if (strlen(resultsav) >1){
                   9410:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9411:   }
1.253     brouard  9412:   if(j == 0){ /* Resultline but no = */
                   9413:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9414:     return (0);
                   9415:   }
                   9416:     
1.234     brouard  9417:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9418:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9419:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9420:   }
                   9421:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9422:     if(nbocc(resultsav,'=') >1){
                   9423:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9424:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9425:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9426:     }else
                   9427:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9428:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9429:     
1.230     brouard  9430:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9431:     Tvarsel[k]=atoi(strc);
                   9432:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9433:     /* cptcovsel++;     */
                   9434:     if (nbocc(stra,'=') >0)
                   9435:       strcpy(resultsav,stra); /* and analyzes it */
                   9436:   }
1.235     brouard  9437:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9438:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9439:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9440:       match=0;
1.236     brouard  9441:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9442:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9443:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9444:          match=1;
                   9445:          break;
                   9446:        }
                   9447:       }
                   9448:       if(match == 0){
                   9449:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9450:       }
                   9451:     }
                   9452:   }
1.235     brouard  9453:   /* Checking for missing or useless values in comparison of current model needs */
                   9454:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9455:     match=0;
1.235     brouard  9456:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9457:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9458:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9459:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9460:          ++match;
                   9461:        }
                   9462:       }
                   9463:     }
                   9464:     if(match == 0){
                   9465:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9466:     }else if(match > 1){
                   9467:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9468:     }
                   9469:   }
1.235     brouard  9470:       
1.234     brouard  9471:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9472:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9473:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9474:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9475:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9476:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9477:   /*    1 0 0 0 */
                   9478:   /*    2 1 0 0 */
                   9479:   /*    3 0 1 0 */ 
                   9480:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9481:   /*    5 0 0 1 */
                   9482:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9483:   /*    7 0 1 1 */
                   9484:   /*    8 1 1 1 */
1.237     brouard  9485:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9486:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9487:   /* V5*age V5 known which value for nres?  */
                   9488:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9489:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9490:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9491:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9492:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9493:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9494:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9495:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9496:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9497:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9498:       k4++;;
                   9499:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9500:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9501:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9502:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9503:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9504:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9505:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9506:       k4q++;;
                   9507:     }
                   9508:   }
1.234     brouard  9509:   
1.235     brouard  9510:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9511:   return (0);
                   9512: }
1.235     brouard  9513: 
1.230     brouard  9514: int decodemodel( char model[], int lastobs)
                   9515:  /**< This routine decodes the model and returns:
1.224     brouard  9516:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9517:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9518:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9519:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9520:        * - cptcovage number of covariates with age*products =2
                   9521:        * - cptcovs number of simple covariates
                   9522:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9523:        *     which is a new column after the 9 (ncovcol) variables. 
                   9524:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9525:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9526:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9527:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9528:        */
1.136     brouard  9529: {
1.238     brouard  9530:   int i, j, k, ks, v;
1.227     brouard  9531:   int  j1, k1, k2, k3, k4;
1.136     brouard  9532:   char modelsav[80];
1.145     brouard  9533:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9534:   char *strpt;
1.136     brouard  9535: 
1.145     brouard  9536:   /*removespace(model);*/
1.136     brouard  9537:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9538:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9539:     if (strstr(model,"AGE") !=0){
1.192     brouard  9540:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9541:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9542:       return 1;
                   9543:     }
1.141     brouard  9544:     if (strstr(model,"v") !=0){
                   9545:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9546:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9547:       return 1;
                   9548:     }
1.187     brouard  9549:     strcpy(modelsav,model); 
                   9550:     if ((strpt=strstr(model,"age*age")) !=0){
                   9551:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9552:       if(strpt != model){
1.234     brouard  9553:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9554:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9555:  corresponding column of parameters.\n",model);
1.234     brouard  9556:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9557:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9558:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9559:        return 1;
1.225     brouard  9560:       }
1.187     brouard  9561:       nagesqr=1;
                   9562:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9563:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9564:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9565:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9566:       else 
1.234     brouard  9567:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9568:     }else
                   9569:       nagesqr=0;
                   9570:     if (strlen(modelsav) >1){
                   9571:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9572:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9573:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9574:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9575:                     * cst, age and age*age 
                   9576:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9577:       /* including age products which are counted in cptcovage.
                   9578:        * but the covariates which are products must be treated 
                   9579:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9580:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9581:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9582:       
                   9583:       
1.187     brouard  9584:       /*   Design
                   9585:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9586:        *  <          ncovcol=8                >
                   9587:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9588:        *   k=  1    2      3       4     5       6      7        8
                   9589:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9590:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9591:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9592:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9593:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9594:        *  Tage[++cptcovage]=k
                   9595:        *       if products, new covar are created after ncovcol with k1
                   9596:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9597:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9598:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9599:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9600:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9601:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9602:        *  <          ncovcol=8                >
                   9603:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9604:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9605:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9606:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9607:        * p Tprod[1]@2={                         6, 5}
                   9608:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9609:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9610:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9611:        *How to reorganize?
                   9612:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9613:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9614:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9615:        * Struct []
                   9616:        */
1.225     brouard  9617:       
1.187     brouard  9618:       /* This loop fills the array Tvar from the string 'model'.*/
                   9619:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9620:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9621:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9622:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9623:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9624:       /*       k=1 Tvar[1]=2 (from V2) */
                   9625:       /*       k=5 Tvar[5] */
                   9626:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9627:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9628:       /*       } */
1.198     brouard  9629:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9630:       /*
                   9631:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9632:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9633:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9634:       }
1.187     brouard  9635:       cptcovage=0;
                   9636:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9637:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9638:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9639:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9640:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9641:        /*scanf("%d",i);*/
                   9642:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9643:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9644:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9645:            /* covar is not filled and then is empty */
                   9646:            cptcovprod--;
                   9647:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9648:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9649:            Typevar[k]=1;  /* 1 for age product */
                   9650:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9651:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9652:            /*printf("stre=%s ", stre);*/
                   9653:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9654:            cptcovprod--;
                   9655:            cutl(stre,strb,strc,'V');
                   9656:            Tvar[k]=atoi(stre);
                   9657:            Typevar[k]=1;  /* 1 for age product */
                   9658:            cptcovage++;
                   9659:            Tage[cptcovage]=k;
                   9660:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9661:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9662:            cptcovn++;
                   9663:            cptcovprodnoage++;k1++;
                   9664:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9665:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9666:                                                because this model-covariate is a construction we invent a new column
                   9667:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9668:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9669:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9670:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9671:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9672:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9673:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9674:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9675:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9676:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9677:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9678:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9679:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9680:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9681:            for (i=1; i<=lastobs;i++){
                   9682:              /* Computes the new covariate which is a product of
                   9683:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9684:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9685:            }
                   9686:          } /* End age is not in the model */
                   9687:        } /* End if model includes a product */
                   9688:        else { /* no more sum */
                   9689:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9690:          /*  scanf("%d",i);*/
                   9691:          cutl(strd,strc,strb,'V');
                   9692:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9693:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9694:          Tvar[k]=atoi(strd);
                   9695:          Typevar[k]=0;  /* 0 for simple covariates */
                   9696:        }
                   9697:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9698:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9699:                                  scanf("%d",i);*/
1.187     brouard  9700:       } /* end of loop + on total covariates */
                   9701:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9702:   } /* end if strlen(model == 0) */
1.136     brouard  9703:   
                   9704:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9705:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9706:   
1.136     brouard  9707:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9708:      printf("cptcovprod=%d ", cptcovprod);
                   9709:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9710:      scanf("%d ",i);*/
                   9711: 
                   9712: 
1.230     brouard  9713: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9714:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9715: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9716:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9717:    k =           1    2   3     4       5       6      7      8        9
                   9718:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9719:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9720:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9721:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9722:          Tmodelind[combination of covar]=k;
1.225     brouard  9723: */  
                   9724: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9725:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9726:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9727:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9728:   printf("Model=%s\n\
                   9729: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9730: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9731: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9732:   fprintf(ficlog,"Model=%s\n\
                   9733: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9734: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9735: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285   ! brouard  9736:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9737:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9738:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9739:       Fixed[k]= 0;
                   9740:       Dummy[k]= 0;
1.225     brouard  9741:       ncoveff++;
1.232     brouard  9742:       ncovf++;
1.234     brouard  9743:       nsd++;
                   9744:       modell[k].maintype= FTYPE;
                   9745:       TvarsD[nsd]=Tvar[k];
                   9746:       TvarsDind[nsd]=k;
                   9747:       TvarF[ncovf]=Tvar[k];
                   9748:       TvarFind[ncovf]=k;
                   9749:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9750:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9751:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9752:       Fixed[k]= 0;
                   9753:       Dummy[k]= 0;
                   9754:       ncoveff++;
                   9755:       ncovf++;
                   9756:       modell[k].maintype= FTYPE;
                   9757:       TvarF[ncovf]=Tvar[k];
                   9758:       TvarFind[ncovf]=k;
1.230     brouard  9759:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9760:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9761:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9762:       Fixed[k]= 0;
                   9763:       Dummy[k]= 1;
1.230     brouard  9764:       nqfveff++;
1.234     brouard  9765:       modell[k].maintype= FTYPE;
                   9766:       modell[k].subtype= FQ;
                   9767:       nsq++;
                   9768:       TvarsQ[nsq]=Tvar[k];
                   9769:       TvarsQind[nsq]=k;
1.232     brouard  9770:       ncovf++;
1.234     brouard  9771:       TvarF[ncovf]=Tvar[k];
                   9772:       TvarFind[ncovf]=k;
1.231     brouard  9773:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9774:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9775:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9776:       Fixed[k]= 1;
                   9777:       Dummy[k]= 0;
1.225     brouard  9778:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9779:       modell[k].maintype= VTYPE;
                   9780:       modell[k].subtype= VD;
                   9781:       nsd++;
                   9782:       TvarsD[nsd]=Tvar[k];
                   9783:       TvarsDind[nsd]=k;
                   9784:       ncovv++; /* Only simple time varying variables */
                   9785:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9786:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9787:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9788:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9789:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9790:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9791:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9792:       Fixed[k]= 1;
                   9793:       Dummy[k]= 1;
                   9794:       nqtveff++;
                   9795:       modell[k].maintype= VTYPE;
                   9796:       modell[k].subtype= VQ;
                   9797:       ncovv++; /* Only simple time varying variables */
                   9798:       nsq++;
                   9799:       TvarsQ[nsq]=Tvar[k];
                   9800:       TvarsQind[nsq]=k;
                   9801:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9802:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9803:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9804:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9805:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9806:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9807:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9808:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9809:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9810:       ncova++;
                   9811:       TvarA[ncova]=Tvar[k];
                   9812:       TvarAind[ncova]=k;
1.231     brouard  9813:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9814:        Fixed[k]= 2;
                   9815:        Dummy[k]= 2;
                   9816:        modell[k].maintype= ATYPE;
                   9817:        modell[k].subtype= APFD;
                   9818:        /* ncoveff++; */
1.227     brouard  9819:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9820:        Fixed[k]= 2;
                   9821:        Dummy[k]= 3;
                   9822:        modell[k].maintype= ATYPE;
                   9823:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9824:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9825:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9826:        Fixed[k]= 3;
                   9827:        Dummy[k]= 2;
                   9828:        modell[k].maintype= ATYPE;
                   9829:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9830:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9831:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9832:        Fixed[k]= 3;
                   9833:        Dummy[k]= 3;
                   9834:        modell[k].maintype= ATYPE;
                   9835:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9836:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9837:       }
                   9838:     }else if (Typevar[k] == 2) {  /* product without age */
                   9839:       k1=Tposprod[k];
                   9840:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9841:        if(Tvard[k1][2] <=ncovcol){
                   9842:          Fixed[k]= 1;
                   9843:          Dummy[k]= 0;
                   9844:          modell[k].maintype= FTYPE;
                   9845:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9846:          ncovf++; /* Fixed variables without age */
                   9847:          TvarF[ncovf]=Tvar[k];
                   9848:          TvarFind[ncovf]=k;
                   9849:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9850:          Fixed[k]= 0;  /* or 2 ?*/
                   9851:          Dummy[k]= 1;
                   9852:          modell[k].maintype= FTYPE;
                   9853:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9854:          ncovf++; /* Varying variables without age */
                   9855:          TvarF[ncovf]=Tvar[k];
                   9856:          TvarFind[ncovf]=k;
                   9857:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9858:          Fixed[k]= 1;
                   9859:          Dummy[k]= 0;
                   9860:          modell[k].maintype= VTYPE;
                   9861:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9862:          ncovv++; /* Varying variables without age */
                   9863:          TvarV[ncovv]=Tvar[k];
                   9864:          TvarVind[ncovv]=k;
                   9865:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9866:          Fixed[k]= 1;
                   9867:          Dummy[k]= 1;
                   9868:          modell[k].maintype= VTYPE;
                   9869:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9870:          ncovv++; /* Varying variables without age */
                   9871:          TvarV[ncovv]=Tvar[k];
                   9872:          TvarVind[ncovv]=k;
                   9873:        }
1.227     brouard  9874:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9875:        if(Tvard[k1][2] <=ncovcol){
                   9876:          Fixed[k]= 0;  /* or 2 ?*/
                   9877:          Dummy[k]= 1;
                   9878:          modell[k].maintype= FTYPE;
                   9879:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9880:          ncovf++; /* Fixed variables without age */
                   9881:          TvarF[ncovf]=Tvar[k];
                   9882:          TvarFind[ncovf]=k;
                   9883:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9884:          Fixed[k]= 1;
                   9885:          Dummy[k]= 1;
                   9886:          modell[k].maintype= VTYPE;
                   9887:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9888:          ncovv++; /* Varying variables without age */
                   9889:          TvarV[ncovv]=Tvar[k];
                   9890:          TvarVind[ncovv]=k;
                   9891:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9892:          Fixed[k]= 1;
                   9893:          Dummy[k]= 1;
                   9894:          modell[k].maintype= VTYPE;
                   9895:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9896:          ncovv++; /* Varying variables without age */
                   9897:          TvarV[ncovv]=Tvar[k];
                   9898:          TvarVind[ncovv]=k;
                   9899:          ncovv++; /* Varying variables without age */
                   9900:          TvarV[ncovv]=Tvar[k];
                   9901:          TvarVind[ncovv]=k;
                   9902:        }
1.227     brouard  9903:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9904:        if(Tvard[k1][2] <=ncovcol){
                   9905:          Fixed[k]= 1;
                   9906:          Dummy[k]= 1;
                   9907:          modell[k].maintype= VTYPE;
                   9908:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9909:          ncovv++; /* Varying variables without age */
                   9910:          TvarV[ncovv]=Tvar[k];
                   9911:          TvarVind[ncovv]=k;
                   9912:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9913:          Fixed[k]= 1;
                   9914:          Dummy[k]= 1;
                   9915:          modell[k].maintype= VTYPE;
                   9916:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9917:          ncovv++; /* Varying variables without age */
                   9918:          TvarV[ncovv]=Tvar[k];
                   9919:          TvarVind[ncovv]=k;
                   9920:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9921:          Fixed[k]= 1;
                   9922:          Dummy[k]= 0;
                   9923:          modell[k].maintype= VTYPE;
                   9924:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9925:          ncovv++; /* Varying variables without age */
                   9926:          TvarV[ncovv]=Tvar[k];
                   9927:          TvarVind[ncovv]=k;
                   9928:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9929:          Fixed[k]= 1;
                   9930:          Dummy[k]= 1;
                   9931:          modell[k].maintype= VTYPE;
                   9932:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9933:          ncovv++; /* Varying variables without age */
                   9934:          TvarV[ncovv]=Tvar[k];
                   9935:          TvarVind[ncovv]=k;
                   9936:        }
1.227     brouard  9937:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9938:        if(Tvard[k1][2] <=ncovcol){
                   9939:          Fixed[k]= 1;
                   9940:          Dummy[k]= 1;
                   9941:          modell[k].maintype= VTYPE;
                   9942:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9943:          ncovv++; /* Varying variables without age */
                   9944:          TvarV[ncovv]=Tvar[k];
                   9945:          TvarVind[ncovv]=k;
                   9946:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9947:          Fixed[k]= 1;
                   9948:          Dummy[k]= 1;
                   9949:          modell[k].maintype= VTYPE;
                   9950:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9951:          ncovv++; /* Varying variables without age */
                   9952:          TvarV[ncovv]=Tvar[k];
                   9953:          TvarVind[ncovv]=k;
                   9954:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9955:          Fixed[k]= 1;
                   9956:          Dummy[k]= 1;
                   9957:          modell[k].maintype= VTYPE;
                   9958:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9959:          ncovv++; /* Varying variables without age */
                   9960:          TvarV[ncovv]=Tvar[k];
                   9961:          TvarVind[ncovv]=k;
                   9962:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9963:          Fixed[k]= 1;
                   9964:          Dummy[k]= 1;
                   9965:          modell[k].maintype= VTYPE;
                   9966:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9967:          ncovv++; /* Varying variables without age */
                   9968:          TvarV[ncovv]=Tvar[k];
                   9969:          TvarVind[ncovv]=k;
                   9970:        }
1.227     brouard  9971:       }else{
1.240     brouard  9972:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9973:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9974:       } /*end k1*/
1.225     brouard  9975:     }else{
1.226     brouard  9976:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9977:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9978:     }
1.227     brouard  9979:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9980:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9981:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9982:   }
                   9983:   /* Searching for doublons in the model */
                   9984:   for(k1=1; k1<= cptcovt;k1++){
                   9985:     for(k2=1; k2 <k1;k2++){
1.285   ! brouard  9986:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
        !          9987:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  9988:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9989:          if(Tvar[k1]==Tvar[k2]){
1.285   ! brouard  9990:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
        !          9991:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  9992:            return(1);
                   9993:          }
                   9994:        }else if (Typevar[k1] ==2){
                   9995:          k3=Tposprod[k1];
                   9996:          k4=Tposprod[k2];
                   9997:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9998:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9999:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10000:            return(1);
                   10001:          }
                   10002:        }
1.227     brouard  10003:       }
                   10004:     }
1.225     brouard  10005:   }
                   10006:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10007:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10008:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10009:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10010:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10011:   /*endread:*/
1.225     brouard  10012:   printf("Exiting decodemodel: ");
                   10013:   return (1);
1.136     brouard  10014: }
                   10015: 
1.169     brouard  10016: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10017: {/* Check ages at death */
1.136     brouard  10018:   int i, m;
1.218     brouard  10019:   int firstone=0;
                   10020:   
1.136     brouard  10021:   for (i=1; i<=imx; i++) {
                   10022:     for(m=2; (m<= maxwav); m++) {
                   10023:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10024:        anint[m][i]=9999;
1.216     brouard  10025:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10026:          s[m][i]=-1;
1.136     brouard  10027:       }
                   10028:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10029:        *nberr = *nberr + 1;
1.218     brouard  10030:        if(firstone == 0){
                   10031:          firstone=1;
1.260     brouard  10032:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10033:        }
1.262     brouard  10034:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10035:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10036:       }
                   10037:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10038:        (*nberr)++;
1.259     brouard  10039:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10040:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10041:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10042:       }
                   10043:     }
                   10044:   }
                   10045: 
                   10046:   for (i=1; i<=imx; i++)  {
                   10047:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10048:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10049:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10050:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10051:          if(agedc[i]>0){
                   10052:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10053:              agev[m][i]=agedc[i];
1.214     brouard  10054:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10055:            }else {
1.136     brouard  10056:              if ((int)andc[i]!=9999){
                   10057:                nbwarn++;
                   10058:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10059:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10060:                agev[m][i]=-1;
                   10061:              }
                   10062:            }
1.169     brouard  10063:          } /* agedc > 0 */
1.214     brouard  10064:        } /* end if */
1.136     brouard  10065:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10066:                                 years but with the precision of a month */
                   10067:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10068:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10069:            agev[m][i]=1;
                   10070:          else if(agev[m][i] < *agemin){ 
                   10071:            *agemin=agev[m][i];
                   10072:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10073:          }
                   10074:          else if(agev[m][i] >*agemax){
                   10075:            *agemax=agev[m][i];
1.156     brouard  10076:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10077:          }
                   10078:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10079:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10080:        } /* en if 9*/
1.136     brouard  10081:        else { /* =9 */
1.214     brouard  10082:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10083:          agev[m][i]=1;
                   10084:          s[m][i]=-1;
                   10085:        }
                   10086:       }
1.214     brouard  10087:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10088:        agev[m][i]=1;
1.214     brouard  10089:       else{
                   10090:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10091:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10092:        agev[m][i]=0;
                   10093:       }
                   10094:     } /* End for lastpass */
                   10095:   }
1.136     brouard  10096:     
                   10097:   for (i=1; i<=imx; i++)  {
                   10098:     for(m=firstpass; (m<=lastpass); m++){
                   10099:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10100:        (*nberr)++;
1.136     brouard  10101:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10102:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10103:        return 1;
                   10104:       }
                   10105:     }
                   10106:   }
                   10107: 
                   10108:   /*for (i=1; i<=imx; i++){
                   10109:   for (m=firstpass; (m<lastpass); m++){
                   10110:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10111: }
                   10112: 
                   10113: }*/
                   10114: 
                   10115: 
1.139     brouard  10116:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10117:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10118: 
                   10119:   return (0);
1.164     brouard  10120:  /* endread:*/
1.136     brouard  10121:     printf("Exiting calandcheckages: ");
                   10122:     return (1);
                   10123: }
                   10124: 
1.172     brouard  10125: #if defined(_MSC_VER)
                   10126: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10127: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10128: //#include "stdafx.h"
                   10129: //#include <stdio.h>
                   10130: //#include <tchar.h>
                   10131: //#include <windows.h>
                   10132: //#include <iostream>
                   10133: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10134: 
                   10135: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10136: 
                   10137: BOOL IsWow64()
                   10138: {
                   10139:        BOOL bIsWow64 = FALSE;
                   10140: 
                   10141:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10142:        //  (HANDLE, PBOOL);
                   10143: 
                   10144:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10145: 
                   10146:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10147:        const char funcName[] = "IsWow64Process";
                   10148:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10149:                GetProcAddress(module, funcName);
                   10150: 
                   10151:        if (NULL != fnIsWow64Process)
                   10152:        {
                   10153:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10154:                        &bIsWow64))
                   10155:                        //throw std::exception("Unknown error");
                   10156:                        printf("Unknown error\n");
                   10157:        }
                   10158:        return bIsWow64 != FALSE;
                   10159: }
                   10160: #endif
1.177     brouard  10161: 
1.191     brouard  10162: void syscompilerinfo(int logged)
1.167     brouard  10163:  {
                   10164:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10165:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10166:    /* /GS /W3 /Gy
                   10167:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10168:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10169:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10170:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10171:    */ 
                   10172:    /* 64 bits */
1.185     brouard  10173:    /*
                   10174:      /GS /W3 /Gy
                   10175:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10176:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10177:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10178:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10179:    /* Optimization are useless and O3 is slower than O2 */
                   10180:    /*
                   10181:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10182:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10183:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10184:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10185:    */
1.186     brouard  10186:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10187:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10188:       /PDB:"visual studio
                   10189:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10190:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10191:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10192:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10193:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10194:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10195:       uiAccess='false'"
                   10196:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10197:       /NOLOGO /TLBID:1
                   10198:    */
1.177     brouard  10199: #if defined __INTEL_COMPILER
1.178     brouard  10200: #if defined(__GNUC__)
                   10201:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10202: #endif
1.177     brouard  10203: #elif defined(__GNUC__) 
1.179     brouard  10204: #ifndef  __APPLE__
1.174     brouard  10205: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10206: #endif
1.177     brouard  10207:    struct utsname sysInfo;
1.178     brouard  10208:    int cross = CROSS;
                   10209:    if (cross){
                   10210:           printf("Cross-");
1.191     brouard  10211:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10212:    }
1.174     brouard  10213: #endif
                   10214: 
1.171     brouard  10215: #include <stdint.h>
1.178     brouard  10216: 
1.191     brouard  10217:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10218: #if defined(__clang__)
1.191     brouard  10219:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10220: #endif
                   10221: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10222:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10223: #endif
                   10224: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10225:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10226: #endif
                   10227: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10228:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10229: #endif
                   10230: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10231:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10232: #endif
                   10233: #if defined(_MSC_VER)
1.191     brouard  10234:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10235: #endif
                   10236: #if defined(__PGI)
1.191     brouard  10237:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10238: #endif
                   10239: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10240:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10241: #endif
1.191     brouard  10242:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10243:    
1.167     brouard  10244: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10245: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10246:     // Windows (x64 and x86)
1.191     brouard  10247:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10248: #elif __unix__ // all unices, not all compilers
                   10249:     // Unix
1.191     brouard  10250:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10251: #elif __linux__
                   10252:     // linux
1.191     brouard  10253:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10254: #elif __APPLE__
1.174     brouard  10255:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10256:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10257: #endif
                   10258: 
                   10259: /*  __MINGW32__          */
                   10260: /*  __CYGWIN__  */
                   10261: /* __MINGW64__  */
                   10262: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10263: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10264: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10265: /* _WIN64  // Defined for applications for Win64. */
                   10266: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10267: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10268: 
1.167     brouard  10269: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10270:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10271: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10272:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10273: #else
1.191     brouard  10274:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10275: #endif
                   10276: 
1.169     brouard  10277: #if defined(__GNUC__)
                   10278: # if defined(__GNUC_PATCHLEVEL__)
                   10279: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10280:                             + __GNUC_MINOR__ * 100 \
                   10281:                             + __GNUC_PATCHLEVEL__)
                   10282: # else
                   10283: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10284:                             + __GNUC_MINOR__ * 100)
                   10285: # endif
1.174     brouard  10286:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10287:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10288: 
                   10289:    if (uname(&sysInfo) != -1) {
                   10290:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10291:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10292:    }
                   10293:    else
                   10294:       perror("uname() error");
1.179     brouard  10295:    //#ifndef __INTEL_COMPILER 
                   10296: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10297:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10298:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10299: #endif
1.169     brouard  10300: #endif
1.172     brouard  10301: 
                   10302:    //   void main()
                   10303:    //   {
1.169     brouard  10304: #if defined(_MSC_VER)
1.174     brouard  10305:    if (IsWow64()){
1.191     brouard  10306:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10307:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10308:    }
                   10309:    else{
1.191     brouard  10310:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10311:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10312:    }
1.172     brouard  10313:    //     printf("\nPress Enter to continue...");
                   10314:    //     getchar();
                   10315:    //   }
                   10316: 
1.169     brouard  10317: #endif
                   10318:    
1.167     brouard  10319: 
1.219     brouard  10320: }
1.136     brouard  10321: 
1.219     brouard  10322: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10323:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10324:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10325:   /* double ftolpl = 1.e-10; */
1.180     brouard  10326:   double age, agebase, agelim;
1.203     brouard  10327:   double tot;
1.180     brouard  10328: 
1.202     brouard  10329:   strcpy(filerespl,"PL_");
                   10330:   strcat(filerespl,fileresu);
                   10331:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10332:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10333:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10334:   }
1.227     brouard  10335:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10336:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10337:   pstamp(ficrespl);
1.203     brouard  10338:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10339:   fprintf(ficrespl,"#Age ");
                   10340:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10341:   fprintf(ficrespl,"\n");
1.180     brouard  10342:   
1.219     brouard  10343:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10344: 
1.219     brouard  10345:   agebase=ageminpar;
                   10346:   agelim=agemaxpar;
1.180     brouard  10347: 
1.227     brouard  10348:   /* i1=pow(2,ncoveff); */
1.234     brouard  10349:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10350:   if (cptcovn < 1){i1=1;}
1.180     brouard  10351: 
1.238     brouard  10352:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10353:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10354:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10355:        continue;
1.235     brouard  10356: 
1.238     brouard  10357:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10358:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10359:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10360:       /* k=k+1; */
                   10361:       /* to clean */
                   10362:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10363:       fprintf(ficrespl,"#******");
                   10364:       printf("#******");
                   10365:       fprintf(ficlog,"#******");
                   10366:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10367:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10368:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10369:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10370:       }
                   10371:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10372:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10373:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10374:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10375:       }
                   10376:       fprintf(ficrespl,"******\n");
                   10377:       printf("******\n");
                   10378:       fprintf(ficlog,"******\n");
                   10379:       if(invalidvarcomb[k]){
                   10380:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10381:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10382:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10383:        continue;
                   10384:       }
1.219     brouard  10385: 
1.238     brouard  10386:       fprintf(ficrespl,"#Age ");
                   10387:       for(j=1;j<=cptcoveff;j++) {
                   10388:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10389:       }
                   10390:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10391:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10392:     
1.238     brouard  10393:       for (age=agebase; age<=agelim; age++){
                   10394:        /* for (age=agebase; age<=agebase; age++){ */
                   10395:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10396:        fprintf(ficrespl,"%.0f ",age );
                   10397:        for(j=1;j<=cptcoveff;j++)
                   10398:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10399:        tot=0.;
                   10400:        for(i=1; i<=nlstate;i++){
                   10401:          tot +=  prlim[i][i];
                   10402:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10403:        }
                   10404:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10405:       } /* Age */
                   10406:       /* was end of cptcod */
                   10407:     } /* cptcov */
                   10408:   } /* nres */
1.219     brouard  10409:   return 0;
1.180     brouard  10410: }
                   10411: 
1.218     brouard  10412: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10413:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10414:        
                   10415:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10416:    * at any age between ageminpar and agemaxpar
                   10417:         */
1.235     brouard  10418:   int i, j, k, i1, nres=0 ;
1.217     brouard  10419:   /* double ftolpl = 1.e-10; */
                   10420:   double age, agebase, agelim;
                   10421:   double tot;
1.218     brouard  10422:   /* double ***mobaverage; */
                   10423:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10424: 
                   10425:   strcpy(fileresplb,"PLB_");
                   10426:   strcat(fileresplb,fileresu);
                   10427:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10428:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10429:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10430:   }
                   10431:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10432:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10433:   pstamp(ficresplb);
                   10434:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10435:   fprintf(ficresplb,"#Age ");
                   10436:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10437:   fprintf(ficresplb,"\n");
                   10438:   
1.218     brouard  10439:   
                   10440:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10441:   
                   10442:   agebase=ageminpar;
                   10443:   agelim=agemaxpar;
                   10444:   
                   10445:   
1.227     brouard  10446:   i1=pow(2,cptcoveff);
1.218     brouard  10447:   if (cptcovn < 1){i1=1;}
1.227     brouard  10448:   
1.238     brouard  10449:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10450:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10451:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10452:        continue;
                   10453:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10454:       fprintf(ficresplb,"#******");
                   10455:       printf("#******");
                   10456:       fprintf(ficlog,"#******");
                   10457:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10458:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10459:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10460:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10461:       }
                   10462:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10463:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10464:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10465:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10466:       }
                   10467:       fprintf(ficresplb,"******\n");
                   10468:       printf("******\n");
                   10469:       fprintf(ficlog,"******\n");
                   10470:       if(invalidvarcomb[k]){
                   10471:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10472:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10473:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10474:        continue;
                   10475:       }
1.218     brouard  10476:     
1.238     brouard  10477:       fprintf(ficresplb,"#Age ");
                   10478:       for(j=1;j<=cptcoveff;j++) {
                   10479:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10480:       }
                   10481:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10482:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10483:     
                   10484:     
1.238     brouard  10485:       for (age=agebase; age<=agelim; age++){
                   10486:        /* for (age=agebase; age<=agebase; age++){ */
                   10487:        if(mobilavproj > 0){
                   10488:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10489:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10490:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10491:        }else if (mobilavproj == 0){
                   10492:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10493:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10494:          exit(1);
                   10495:        }else{
                   10496:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10497:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10498:          /* printf("TOTOT\n"); */
                   10499:           /* exit(1); */
1.238     brouard  10500:        }
                   10501:        fprintf(ficresplb,"%.0f ",age );
                   10502:        for(j=1;j<=cptcoveff;j++)
                   10503:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10504:        tot=0.;
                   10505:        for(i=1; i<=nlstate;i++){
                   10506:          tot +=  bprlim[i][i];
                   10507:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10508:        }
                   10509:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10510:       } /* Age */
                   10511:       /* was end of cptcod */
1.255     brouard  10512:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10513:     } /* end of any combination */
                   10514:   } /* end of nres */  
1.218     brouard  10515:   /* hBijx(p, bage, fage); */
                   10516:   /* fclose(ficrespijb); */
                   10517:   
                   10518:   return 0;
1.217     brouard  10519: }
1.218     brouard  10520:  
1.180     brouard  10521: int hPijx(double *p, int bage, int fage){
                   10522:     /*------------- h Pij x at various ages ------------*/
                   10523: 
                   10524:   int stepsize;
                   10525:   int agelim;
                   10526:   int hstepm;
                   10527:   int nhstepm;
1.235     brouard  10528:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10529: 
                   10530:   double agedeb;
                   10531:   double ***p3mat;
                   10532: 
1.201     brouard  10533:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10534:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10535:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10536:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10537:     }
                   10538:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10539:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10540:   
                   10541:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10542:     /*if (stepm<=24) stepsize=2;*/
                   10543: 
                   10544:     agelim=AGESUP;
                   10545:     hstepm=stepsize*YEARM; /* Every year of age */
                   10546:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10547:                
1.180     brouard  10548:     /* hstepm=1;   aff par mois*/
                   10549:     pstamp(ficrespij);
                   10550:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10551:     i1= pow(2,cptcoveff);
1.218     brouard  10552:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10553:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10554:                /*      k=k+1;  */
1.235     brouard  10555:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10556:     for(k=1; k<=i1;k++){
1.253     brouard  10557:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10558:        continue;
1.183     brouard  10559:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10560:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10561:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10562:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10563:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10564:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10565:       }
1.183     brouard  10566:       fprintf(ficrespij,"******\n");
                   10567:       
                   10568:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10569:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10570:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10571:        
                   10572:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10573:        
1.183     brouard  10574:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10575:        oldm=oldms;savm=savms;
1.235     brouard  10576:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10577:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10578:        for(i=1; i<=nlstate;i++)
                   10579:          for(j=1; j<=nlstate+ndeath;j++)
                   10580:            fprintf(ficrespij," %1d-%1d",i,j);
                   10581:        fprintf(ficrespij,"\n");
                   10582:        for (h=0; h<=nhstepm; h++){
                   10583:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10584:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10585:          for(i=1; i<=nlstate;i++)
                   10586:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10587:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10588:          fprintf(ficrespij,"\n");
                   10589:        }
1.183     brouard  10590:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10591:        fprintf(ficrespij,"\n");
                   10592:       }
1.180     brouard  10593:       /*}*/
                   10594:     }
1.218     brouard  10595:     return 0;
1.180     brouard  10596: }
1.218     brouard  10597:  
                   10598:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10599:     /*------------- h Bij x at various ages ------------*/
                   10600: 
                   10601:   int stepsize;
1.218     brouard  10602:   /* int agelim; */
                   10603:        int ageminl;
1.217     brouard  10604:   int hstepm;
                   10605:   int nhstepm;
1.238     brouard  10606:   int h, i, i1, j, k, nres;
1.218     brouard  10607:        
1.217     brouard  10608:   double agedeb;
                   10609:   double ***p3mat;
1.218     brouard  10610:        
                   10611:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10612:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10613:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10614:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10615:   }
                   10616:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10617:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10618:   
                   10619:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10620:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10621:   
1.218     brouard  10622:   /* agelim=AGESUP; */
                   10623:   ageminl=30;
                   10624:   hstepm=stepsize*YEARM; /* Every year of age */
                   10625:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10626:   
                   10627:   /* hstepm=1;   aff par mois*/
                   10628:   pstamp(ficrespijb);
1.255     brouard  10629:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10630:   i1= pow(2,cptcoveff);
1.218     brouard  10631:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10632:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10633:   /*   k=k+1;  */
1.238     brouard  10634:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10635:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10636:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10637:        continue;
                   10638:       fprintf(ficrespijb,"\n#****** ");
                   10639:       for(j=1;j<=cptcoveff;j++)
                   10640:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10641:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10642:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10643:       }
                   10644:       fprintf(ficrespijb,"******\n");
1.264     brouard  10645:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10646:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10647:        continue;
                   10648:       }
                   10649:       
                   10650:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10651:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10652:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10653:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10654:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10655:        
                   10656:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10657:        
1.266     brouard  10658:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10659:        /* and memory limitations if stepm is small */
                   10660: 
1.238     brouard  10661:        /* oldm=oldms;savm=savms; */
                   10662:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10663:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10664:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10665:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10666:        for(i=1; i<=nlstate;i++)
                   10667:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10668:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10669:        fprintf(ficrespijb,"\n");
1.238     brouard  10670:        for (h=0; h<=nhstepm; h++){
                   10671:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10672:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10673:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10674:          for(i=1; i<=nlstate;i++)
                   10675:            for(j=1; j<=nlstate+ndeath;j++)
                   10676:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10677:          fprintf(ficrespijb,"\n");
                   10678:        }
                   10679:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10680:        fprintf(ficrespijb,"\n");
                   10681:       } /* end age deb */
                   10682:     } /* end combination */
                   10683:   } /* end nres */
1.218     brouard  10684:   return 0;
                   10685:  } /*  hBijx */
1.217     brouard  10686: 
1.180     brouard  10687: 
1.136     brouard  10688: /***********************************************/
                   10689: /**************** Main Program *****************/
                   10690: /***********************************************/
                   10691: 
                   10692: int main(int argc, char *argv[])
                   10693: {
                   10694: #ifdef GSL
                   10695:   const gsl_multimin_fminimizer_type *T;
                   10696:   size_t iteri = 0, it;
                   10697:   int rval = GSL_CONTINUE;
                   10698:   int status = GSL_SUCCESS;
                   10699:   double ssval;
                   10700: #endif
                   10701:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10702:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10703:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10704:   int jj, ll, li, lj, lk;
1.136     brouard  10705:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10706:   int num_filled;
1.136     brouard  10707:   int itimes;
                   10708:   int NDIM=2;
                   10709:   int vpopbased=0;
1.235     brouard  10710:   int nres=0;
1.258     brouard  10711:   int endishere=0;
1.277     brouard  10712:   int noffset=0;
1.274     brouard  10713:   int ncurrv=0; /* Temporary variable */
                   10714:   
1.164     brouard  10715:   char ca[32], cb[32];
1.136     brouard  10716:   /*  FILE *fichtm; *//* Html File */
                   10717:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10718:   struct stat info;
1.191     brouard  10719:   double agedeb=0.;
1.194     brouard  10720: 
                   10721:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10722:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10723: 
1.165     brouard  10724:   double fret;
1.191     brouard  10725:   double dum=0.; /* Dummy variable */
1.136     brouard  10726:   double ***p3mat;
1.218     brouard  10727:   /* double ***mobaverage; */
1.164     brouard  10728: 
                   10729:   char line[MAXLINE];
1.197     brouard  10730:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10731: 
1.234     brouard  10732:   char  modeltemp[MAXLINE];
1.230     brouard  10733:   char resultline[MAXLINE];
                   10734:   
1.136     brouard  10735:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10736:   char *tok, *val; /* pathtot */
1.136     brouard  10737:   int firstobs=1, lastobs=10;
1.195     brouard  10738:   int c,  h , cpt, c2;
1.191     brouard  10739:   int jl=0;
                   10740:   int i1, j1, jk, stepsize=0;
1.194     brouard  10741:   int count=0;
                   10742: 
1.164     brouard  10743:   int *tab; 
1.136     brouard  10744:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10745:   int backcast=0;
1.136     brouard  10746:   int mobilav=0,popforecast=0;
1.191     brouard  10747:   int hstepm=0, nhstepm=0;
1.136     brouard  10748:   int agemortsup;
                   10749:   float  sumlpop=0.;
                   10750:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10751:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10752: 
1.191     brouard  10753:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10754:   double ftolpl=FTOL;
                   10755:   double **prlim;
1.217     brouard  10756:   double **bprlim;
1.136     brouard  10757:   double ***param; /* Matrix of parameters */
1.251     brouard  10758:   double ***paramstart; /* Matrix of starting parameter values */
                   10759:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10760:   double **matcov; /* Matrix of covariance */
1.203     brouard  10761:   double **hess; /* Hessian matrix */
1.136     brouard  10762:   double ***delti3; /* Scale */
                   10763:   double *delti; /* Scale */
                   10764:   double ***eij, ***vareij;
                   10765:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10766: 
1.136     brouard  10767:   double *epj, vepp;
1.164     brouard  10768: 
1.273     brouard  10769:   double dateprev1, dateprev2;
                   10770:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10771:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10772: 
1.136     brouard  10773:   double **ximort;
1.145     brouard  10774:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10775:   int *dcwave;
                   10776: 
1.164     brouard  10777:   char z[1]="c";
1.136     brouard  10778: 
                   10779:   /*char  *strt;*/
                   10780:   char strtend[80];
1.126     brouard  10781: 
1.164     brouard  10782: 
1.126     brouard  10783: /*   setlocale (LC_ALL, ""); */
                   10784: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10785: /*   textdomain (PACKAGE); */
                   10786: /*   setlocale (LC_CTYPE, ""); */
                   10787: /*   setlocale (LC_MESSAGES, ""); */
                   10788: 
                   10789:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10790:   rstart_time = time(NULL);  
                   10791:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10792:   start_time = *localtime(&rstart_time);
1.126     brouard  10793:   curr_time=start_time;
1.157     brouard  10794:   /*tml = *localtime(&start_time.tm_sec);*/
                   10795:   /* strcpy(strstart,asctime(&tml)); */
                   10796:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10797: 
                   10798: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10799: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10800: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10801: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10802: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10803: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10804: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10805: /*   strt=asctime(&tmg); */
                   10806: /*   printf("Time(after) =%s",strstart);  */
                   10807: /*  (void) time (&time_value);
                   10808: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10809: *  tm = *localtime(&time_value);
                   10810: *  strstart=asctime(&tm);
                   10811: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10812: */
                   10813: 
                   10814:   nberr=0; /* Number of errors and warnings */
                   10815:   nbwarn=0;
1.184     brouard  10816: #ifdef WIN32
                   10817:   _getcwd(pathcd, size);
                   10818: #else
1.126     brouard  10819:   getcwd(pathcd, size);
1.184     brouard  10820: #endif
1.191     brouard  10821:   syscompilerinfo(0);
1.196     brouard  10822:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10823:   if(argc <=1){
                   10824:     printf("\nEnter the parameter file name: ");
1.205     brouard  10825:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10826:       printf("ERROR Empty parameter file name\n");
                   10827:       goto end;
                   10828:     }
1.126     brouard  10829:     i=strlen(pathr);
                   10830:     if(pathr[i-1]=='\n')
                   10831:       pathr[i-1]='\0';
1.156     brouard  10832:     i=strlen(pathr);
1.205     brouard  10833:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10834:       pathr[i-1]='\0';
1.205     brouard  10835:     }
                   10836:     i=strlen(pathr);
                   10837:     if( i==0 ){
                   10838:       printf("ERROR Empty parameter file name\n");
                   10839:       goto end;
                   10840:     }
                   10841:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10842:       printf("Pathr |%s|\n",pathr);
                   10843:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10844:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10845:       strcpy (pathtot, val);
                   10846:       if(pathr[0] == '\0') break; /* Dirty */
                   10847:     }
                   10848:   }
1.281     brouard  10849:   else if (argc<=2){
                   10850:     strcpy(pathtot,argv[1]);
                   10851:   }
1.126     brouard  10852:   else{
                   10853:     strcpy(pathtot,argv[1]);
1.281     brouard  10854:     strcpy(z,argv[2]);
                   10855:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10856:   }
                   10857:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10858:   /*cygwin_split_path(pathtot,path,optionfile);
                   10859:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10860:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10861: 
                   10862:   /* Split argv[0], imach program to get pathimach */
                   10863:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10864:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10865:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10866:  /*   strcpy(pathimach,argv[0]); */
                   10867:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10868:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10869:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10870: #ifdef WIN32
                   10871:   _chdir(path); /* Can be a relative path */
                   10872:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10873: #else
1.126     brouard  10874:   chdir(path); /* Can be a relative path */
1.184     brouard  10875:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10876: #endif
                   10877:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10878:   strcpy(command,"mkdir ");
                   10879:   strcat(command,optionfilefiname);
                   10880:   if((outcmd=system(command)) != 0){
1.169     brouard  10881:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10882:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10883:     /* fclose(ficlog); */
                   10884: /*     exit(1); */
                   10885:   }
                   10886: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10887: /*     perror("mkdir"); */
                   10888: /*   } */
                   10889: 
                   10890:   /*-------- arguments in the command line --------*/
                   10891: 
1.186     brouard  10892:   /* Main Log file */
1.126     brouard  10893:   strcat(filelog, optionfilefiname);
                   10894:   strcat(filelog,".log");    /* */
                   10895:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10896:     printf("Problem with logfile %s\n",filelog);
                   10897:     goto end;
                   10898:   }
                   10899:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10900:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10901:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10902:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10903:  path=%s \n\
                   10904:  optionfile=%s\n\
                   10905:  optionfilext=%s\n\
1.156     brouard  10906:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10907: 
1.197     brouard  10908:   syscompilerinfo(1);
1.167     brouard  10909: 
1.126     brouard  10910:   printf("Local time (at start):%s",strstart);
                   10911:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10912:   fflush(ficlog);
                   10913: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10914: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10915: 
                   10916:   /* */
                   10917:   strcpy(fileres,"r");
                   10918:   strcat(fileres, optionfilefiname);
1.201     brouard  10919:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10920:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10921:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10922: 
1.186     brouard  10923:   /* Main ---------arguments file --------*/
1.126     brouard  10924: 
                   10925:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10926:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10927:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10928:     fflush(ficlog);
1.149     brouard  10929:     /* goto end; */
                   10930:     exit(70); 
1.126     brouard  10931:   }
                   10932: 
                   10933:   strcpy(filereso,"o");
1.201     brouard  10934:   strcat(filereso,fileresu);
1.126     brouard  10935:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10936:     printf("Problem with Output resultfile: %s\n", filereso);
                   10937:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10938:     fflush(ficlog);
                   10939:     goto end;
                   10940:   }
1.278     brouard  10941:       /*-------- Rewriting parameter file ----------*/
                   10942:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10943:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10944:   strcat(rfileres,".");    /* */
                   10945:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10946:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10947:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10948:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10949:     fflush(ficlog);
                   10950:     goto end;
                   10951:   }
                   10952:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10953: 
1.278     brouard  10954:                                      
1.126     brouard  10955:   /* Reads comments: lines beginning with '#' */
                   10956:   numlinepar=0;
1.277     brouard  10957:   /* Is it a BOM UTF-8 Windows file? */
                   10958:   /* First parameter line */
1.197     brouard  10959:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10960:     noffset=0;
                   10961:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10962:     {
                   10963:       noffset=noffset+3;
                   10964:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10965:     }
                   10966:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10967:     {
                   10968:       noffset=noffset+2;
                   10969:       printf("# File is an UTF16BE BOM file\n");
                   10970:     }
                   10971:     else if( line[0] == 0 && line[1] == 0)
                   10972:     {
                   10973:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   10974:        noffset=noffset+4;
                   10975:        printf("# File is an UTF16BE BOM file\n");
                   10976:       }
                   10977:     } else{
                   10978:       ;/*printf(" Not a BOM file\n");*/
                   10979:     }
                   10980:   
1.197     brouard  10981:     /* If line starts with a # it is a comment */
1.277     brouard  10982:     if (line[noffset] == '#') {
1.197     brouard  10983:       numlinepar++;
                   10984:       fputs(line,stdout);
                   10985:       fputs(line,ficparo);
1.278     brouard  10986:       fputs(line,ficres);
1.197     brouard  10987:       fputs(line,ficlog);
                   10988:       continue;
                   10989:     }else
                   10990:       break;
                   10991:   }
                   10992:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10993:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10994:     if (num_filled != 5) {
                   10995:       printf("Should be 5 parameters\n");
1.283     brouard  10996:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  10997:     }
1.126     brouard  10998:     numlinepar++;
1.197     brouard  10999:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11000:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11001:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11002:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11003:   }
                   11004:   /* Second parameter line */
                   11005:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11006:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11007:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11008:     if (line[0] == '#') {
                   11009:       numlinepar++;
1.283     brouard  11010:       printf("%s",line);
                   11011:       fprintf(ficres,"%s",line);
                   11012:       fprintf(ficparo,"%s",line);
                   11013:       fprintf(ficlog,"%s",line);
1.197     brouard  11014:       continue;
                   11015:     }else
                   11016:       break;
                   11017:   }
1.223     brouard  11018:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11019:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11020:     if (num_filled != 11) {
                   11021:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11022:       printf("but line=%s\n",line);
1.283     brouard  11023:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11024:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11025:     }
1.223     brouard  11026:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11027:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
                   11028:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
                   11029:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11030:   }
1.203     brouard  11031:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11032:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11033:   /* Third parameter line */
                   11034:   while(fgets(line, MAXLINE, ficpar)) {
                   11035:     /* If line starts with a # it is a comment */
                   11036:     if (line[0] == '#') {
                   11037:       numlinepar++;
1.283     brouard  11038:       printf("%s",line);
                   11039:       fprintf(ficres,"%s",line);
                   11040:       fprintf(ficparo,"%s",line);
                   11041:       fprintf(ficlog,"%s",line);
1.197     brouard  11042:       continue;
                   11043:     }else
                   11044:       break;
                   11045:   }
1.201     brouard  11046:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11047:     if (num_filled != 1){
                   11048:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11049:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11050:       model[0]='\0';
                   11051:       goto end;
                   11052:     }
                   11053:     else{
                   11054:       if (model[0]=='+'){
                   11055:        for(i=1; i<=strlen(model);i++)
                   11056:          modeltemp[i-1]=model[i];
1.201     brouard  11057:        strcpy(model,modeltemp); 
1.197     brouard  11058:       }
                   11059:     }
1.199     brouard  11060:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11061:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11062:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11063:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11064:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11065:   }
                   11066:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11067:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11068:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11069:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11070:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11071:   fflush(ficlog);
1.190     brouard  11072:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11073:   if(model[0]=='#'){
1.279     brouard  11074:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11075:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11076:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11077:     if(mle != -1){
1.279     brouard  11078:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11079:       exit(1);
                   11080:     }
                   11081:   }
1.126     brouard  11082:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11083:     ungetc(c,ficpar);
                   11084:     fgets(line, MAXLINE, ficpar);
                   11085:     numlinepar++;
1.195     brouard  11086:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11087:       z[0]=line[1];
                   11088:     }
                   11089:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11090:     fputs(line, stdout);
                   11091:     //puts(line);
1.126     brouard  11092:     fputs(line,ficparo);
                   11093:     fputs(line,ficlog);
                   11094:   }
                   11095:   ungetc(c,ficpar);
                   11096: 
                   11097:    
1.145     brouard  11098:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11099:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11100:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11101:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11102:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11103:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11104:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11105:   */
                   11106:   if (strlen(model)>1) 
1.187     brouard  11107:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11108:   else
1.187     brouard  11109:     ncovmodel=2; /* Constant and age */
1.133     brouard  11110:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11111:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11112:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11113:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11114:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11115:     fflush(stdout);
                   11116:     fclose (ficlog);
                   11117:     goto end;
                   11118:   }
1.126     brouard  11119:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11120:   delti=delti3[1][1];
                   11121:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11122:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11123: /* We could also provide initial parameters values giving by simple logistic regression 
                   11124:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11125:       /* for(i=1;i<nlstate;i++){ */
                   11126:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11127:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11128:       /* } */
1.126     brouard  11129:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11130:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11131:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11132:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11133:     fclose (ficparo);
                   11134:     fclose (ficlog);
                   11135:     goto end;
                   11136:     exit(0);
1.220     brouard  11137:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11138:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11139:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11140:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11141:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11142:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11143:     hess=matrix(1,npar,1,npar);
1.220     brouard  11144:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11145:     /* Read guessed parameters */
1.126     brouard  11146:     /* Reads comments: lines beginning with '#' */
                   11147:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11148:       ungetc(c,ficpar);
                   11149:       fgets(line, MAXLINE, ficpar);
                   11150:       numlinepar++;
1.141     brouard  11151:       fputs(line,stdout);
1.126     brouard  11152:       fputs(line,ficparo);
                   11153:       fputs(line,ficlog);
                   11154:     }
                   11155:     ungetc(c,ficpar);
                   11156:     
                   11157:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11158:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11159:     for(i=1; i <=nlstate; i++){
1.234     brouard  11160:       j=0;
1.126     brouard  11161:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11162:        if(jj==i) continue;
                   11163:        j++;
                   11164:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11165:        if ((i1 != i) || (j1 != jj)){
                   11166:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11167: It might be a problem of design; if ncovcol and the model are correct\n \
                   11168: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11169:          exit(1);
                   11170:        }
                   11171:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11172:        if(mle==1)
                   11173:          printf("%1d%1d",i,jj);
                   11174:        fprintf(ficlog,"%1d%1d",i,jj);
                   11175:        for(k=1; k<=ncovmodel;k++){
                   11176:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11177:          if(mle==1){
                   11178:            printf(" %lf",param[i][j][k]);
                   11179:            fprintf(ficlog," %lf",param[i][j][k]);
                   11180:          }
                   11181:          else
                   11182:            fprintf(ficlog," %lf",param[i][j][k]);
                   11183:          fprintf(ficparo," %lf",param[i][j][k]);
                   11184:        }
                   11185:        fscanf(ficpar,"\n");
                   11186:        numlinepar++;
                   11187:        if(mle==1)
                   11188:          printf("\n");
                   11189:        fprintf(ficlog,"\n");
                   11190:        fprintf(ficparo,"\n");
1.126     brouard  11191:       }
                   11192:     }  
                   11193:     fflush(ficlog);
1.234     brouard  11194:     
1.251     brouard  11195:     /* Reads parameters values */
1.126     brouard  11196:     p=param[1][1];
1.251     brouard  11197:     pstart=paramstart[1][1];
1.126     brouard  11198:     
                   11199:     /* Reads comments: lines beginning with '#' */
                   11200:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11201:       ungetc(c,ficpar);
                   11202:       fgets(line, MAXLINE, ficpar);
                   11203:       numlinepar++;
1.141     brouard  11204:       fputs(line,stdout);
1.126     brouard  11205:       fputs(line,ficparo);
                   11206:       fputs(line,ficlog);
                   11207:     }
                   11208:     ungetc(c,ficpar);
                   11209: 
                   11210:     for(i=1; i <=nlstate; i++){
                   11211:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11212:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11213:        if ( (i1-i) * (j1-j) != 0){
                   11214:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11215:          exit(1);
                   11216:        }
                   11217:        printf("%1d%1d",i,j);
                   11218:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11219:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11220:        for(k=1; k<=ncovmodel;k++){
                   11221:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11222:          printf(" %le",delti3[i][j][k]);
                   11223:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11224:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11225:        }
                   11226:        fscanf(ficpar,"\n");
                   11227:        numlinepar++;
                   11228:        printf("\n");
                   11229:        fprintf(ficparo,"\n");
                   11230:        fprintf(ficlog,"\n");
1.126     brouard  11231:       }
                   11232:     }
                   11233:     fflush(ficlog);
1.234     brouard  11234:     
1.145     brouard  11235:     /* Reads covariance matrix */
1.126     brouard  11236:     delti=delti3[1][1];
1.220     brouard  11237:                
                   11238:                
1.126     brouard  11239:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11240:                
1.126     brouard  11241:     /* Reads comments: lines beginning with '#' */
                   11242:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11243:       ungetc(c,ficpar);
                   11244:       fgets(line, MAXLINE, ficpar);
                   11245:       numlinepar++;
1.141     brouard  11246:       fputs(line,stdout);
1.126     brouard  11247:       fputs(line,ficparo);
                   11248:       fputs(line,ficlog);
                   11249:     }
                   11250:     ungetc(c,ficpar);
1.220     brouard  11251:                
1.126     brouard  11252:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11253:     hess=matrix(1,npar,1,npar);
1.131     brouard  11254:     for(i=1; i <=npar; i++)
                   11255:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11256:                
1.194     brouard  11257:     /* Scans npar lines */
1.126     brouard  11258:     for(i=1; i <=npar; i++){
1.226     brouard  11259:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11260:       if(count != 3){
1.226     brouard  11261:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11262: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11263: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11264:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11265: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11266: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11267:        exit(1);
1.220     brouard  11268:       }else{
1.226     brouard  11269:        if(mle==1)
                   11270:          printf("%1d%1d%d",i1,j1,jk);
                   11271:       }
                   11272:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11273:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11274:       for(j=1; j <=i; j++){
1.226     brouard  11275:        fscanf(ficpar," %le",&matcov[i][j]);
                   11276:        if(mle==1){
                   11277:          printf(" %.5le",matcov[i][j]);
                   11278:        }
                   11279:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11280:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11281:       }
                   11282:       fscanf(ficpar,"\n");
                   11283:       numlinepar++;
                   11284:       if(mle==1)
1.220     brouard  11285:                                printf("\n");
1.126     brouard  11286:       fprintf(ficlog,"\n");
                   11287:       fprintf(ficparo,"\n");
                   11288:     }
1.194     brouard  11289:     /* End of read covariance matrix npar lines */
1.126     brouard  11290:     for(i=1; i <=npar; i++)
                   11291:       for(j=i+1;j<=npar;j++)
1.226     brouard  11292:        matcov[i][j]=matcov[j][i];
1.126     brouard  11293:     
                   11294:     if(mle==1)
                   11295:       printf("\n");
                   11296:     fprintf(ficlog,"\n");
                   11297:     
                   11298:     fflush(ficlog);
                   11299:     
                   11300:   }    /* End of mle != -3 */
1.218     brouard  11301:   
1.186     brouard  11302:   /*  Main data
                   11303:    */
1.126     brouard  11304:   n= lastobs;
                   11305:   num=lvector(1,n);
                   11306:   moisnais=vector(1,n);
                   11307:   annais=vector(1,n);
                   11308:   moisdc=vector(1,n);
                   11309:   andc=vector(1,n);
1.220     brouard  11310:   weight=vector(1,n);
1.126     brouard  11311:   agedc=vector(1,n);
                   11312:   cod=ivector(1,n);
1.220     brouard  11313:   for(i=1;i<=n;i++){
1.234     brouard  11314:     num[i]=0;
                   11315:     moisnais[i]=0;
                   11316:     annais[i]=0;
                   11317:     moisdc[i]=0;
                   11318:     andc[i]=0;
                   11319:     agedc[i]=0;
                   11320:     cod[i]=0;
                   11321:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11322:   }
1.126     brouard  11323:   mint=matrix(1,maxwav,1,n);
                   11324:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11325:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11326:   tab=ivector(1,NCOVMAX);
1.144     brouard  11327:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11328:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11329: 
1.136     brouard  11330:   /* Reads data from file datafile */
                   11331:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11332:     goto end;
                   11333: 
                   11334:   /* Calculation of the number of parameters from char model */
1.234     brouard  11335:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11336:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11337:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11338:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11339:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11340:   */
                   11341:   
                   11342:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11343:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11344:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11345:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11346:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11347:   TvarF=ivector(1,NCOVMAX); /*  */
                   11348:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11349:   TvarV=ivector(1,NCOVMAX); /*  */
                   11350:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11351:   TvarA=ivector(1,NCOVMAX); /*  */
                   11352:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11353:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11354:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11355:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11356:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11357:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11358:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11359:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11360:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11361: 
1.230     brouard  11362:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11363:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11364:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11365:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11366:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11367:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11368:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11369:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11370:   */
                   11371:   /* For model-covariate k tells which data-covariate to use but
                   11372:     because this model-covariate is a construction we invent a new column
                   11373:     ncovcol + k1
                   11374:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11375:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11376:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11377:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11378:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11379:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11380:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11381:   */
1.145     brouard  11382:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11383:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11384:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11385:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11386:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11387:                         4 covariates (3 plus signs)
                   11388:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11389:                      */  
1.230     brouard  11390:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11391:                                * individual dummy, fixed or varying:
                   11392:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11393:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11394:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11395:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11396:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11397:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11398:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11399:                                * individual quantitative, fixed or varying:
                   11400:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11401:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11402:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11403: /* Main decodemodel */
                   11404: 
1.187     brouard  11405: 
1.223     brouard  11406:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11407:     goto end;
                   11408: 
1.137     brouard  11409:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11410:     nbwarn++;
                   11411:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11412:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11413:   }
1.136     brouard  11414:     /*  if(mle==1){*/
1.137     brouard  11415:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11416:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11417:   }
                   11418: 
                   11419:     /*-calculation of age at interview from date of interview and age at death -*/
                   11420:   agev=matrix(1,maxwav,1,imx);
                   11421: 
                   11422:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11423:     goto end;
                   11424: 
1.126     brouard  11425: 
1.136     brouard  11426:   agegomp=(int)agemin;
                   11427:   free_vector(moisnais,1,n);
                   11428:   free_vector(annais,1,n);
1.126     brouard  11429:   /* free_matrix(mint,1,maxwav,1,n);
                   11430:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11431:   /* free_vector(moisdc,1,n); */
                   11432:   /* free_vector(andc,1,n); */
1.145     brouard  11433:   /* */
                   11434:   
1.126     brouard  11435:   wav=ivector(1,imx);
1.214     brouard  11436:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11437:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11438:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11439:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11440:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11441:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11442:    
                   11443:   /* Concatenates waves */
1.214     brouard  11444:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11445:      Death is a valid wave (if date is known).
                   11446:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11447:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11448:      and mw[mi+1][i]. dh depends on stepm.
                   11449:   */
                   11450: 
1.126     brouard  11451:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11452:   /* Concatenates waves */
1.145     brouard  11453:  
1.215     brouard  11454:   free_vector(moisdc,1,n);
                   11455:   free_vector(andc,1,n);
                   11456: 
1.126     brouard  11457:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11458:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11459:   ncodemax[1]=1;
1.145     brouard  11460:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11461:   cptcoveff=0;
1.220     brouard  11462:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11463:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11464:   }
                   11465:   
                   11466:   ncovcombmax=pow(2,cptcoveff);
                   11467:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11468:   for(i=1;i<ncovcombmax;i++)
                   11469:     invalidvarcomb[i]=0;
                   11470:   
1.211     brouard  11471:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11472:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11473:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11474:   
1.200     brouard  11475:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11476:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11477:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11478:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11479:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11480:    * (currently 0 or 1) in the data.
                   11481:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11482:    * corresponding modality (h,j).
                   11483:    */
                   11484: 
1.145     brouard  11485:   h=0;
                   11486:   /*if (cptcovn > 0) */
1.126     brouard  11487:   m=pow(2,cptcoveff);
                   11488:  
1.144     brouard  11489:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11490:           * For k=4 covariates, h goes from 1 to m=2**k
                   11491:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11492:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11493:           *     h\k   1     2     3     4
1.143     brouard  11494:           *______________________________  
                   11495:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11496:           *     2     2     1     1     1
                   11497:           *     3 i=2 1     2     1     1
                   11498:           *     4     2     2     1     1
                   11499:           *     5 i=3 1 i=2 1     2     1
                   11500:           *     6     2     1     2     1
                   11501:           *     7 i=4 1     2     2     1
                   11502:           *     8     2     2     2     1
1.197     brouard  11503:           *     9 i=5 1 i=3 1 i=2 1     2
                   11504:           *    10     2     1     1     2
                   11505:           *    11 i=6 1     2     1     2
                   11506:           *    12     2     2     1     2
                   11507:           *    13 i=7 1 i=4 1     2     2    
                   11508:           *    14     2     1     2     2
                   11509:           *    15 i=8 1     2     2     2
                   11510:           *    16     2     2     2     2
1.143     brouard  11511:           */
1.212     brouard  11512:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11513:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11514:      * and the value of each covariate?
                   11515:      * V1=1, V2=1, V3=2, V4=1 ?
                   11516:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11517:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11518:      * In order to get the real value in the data, we use nbcode
                   11519:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11520:      * We are keeping this crazy system in order to be able (in the future?) 
                   11521:      * to have more than 2 values (0 or 1) for a covariate.
                   11522:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11523:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11524:      *              bbbbbbbb
                   11525:      *              76543210     
                   11526:      *   h-1        00000101 (6-1=5)
1.219     brouard  11527:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11528:      *           &
                   11529:      *     1        00000001 (1)
1.219     brouard  11530:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11531:      *          +1= 00000001 =1 
1.211     brouard  11532:      *
                   11533:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11534:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11535:      *    >>k'            11
                   11536:      *          &   00000001
                   11537:      *            = 00000001
                   11538:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11539:      * Reverse h=6 and m=16?
                   11540:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11541:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11542:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11543:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11544:      * V3=decodtabm(14,3,2**4)=2
                   11545:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11546:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11547:      *          &1 000000001
                   11548:      *           = 000000001
                   11549:      *         +1= 000000010 =2
                   11550:      *                  2211
                   11551:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11552:      *                  V3=2
1.220     brouard  11553:                 * codtabm and decodtabm are identical
1.211     brouard  11554:      */
                   11555: 
1.145     brouard  11556: 
                   11557:  free_ivector(Ndum,-1,NCOVMAX);
                   11558: 
                   11559: 
1.126     brouard  11560:     
1.186     brouard  11561:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11562:   strcpy(optionfilegnuplot,optionfilefiname);
                   11563:   if(mle==-3)
1.201     brouard  11564:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11565:   strcat(optionfilegnuplot,".gp");
                   11566: 
                   11567:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11568:     printf("Problem with file %s",optionfilegnuplot);
                   11569:   }
                   11570:   else{
1.204     brouard  11571:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11572:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11573:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11574:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11575:   }
                   11576:   /*  fclose(ficgp);*/
1.186     brouard  11577: 
                   11578: 
                   11579:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11580: 
                   11581:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11582:   if(mle==-3)
1.201     brouard  11583:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11584:   strcat(optionfilehtm,".htm");
                   11585:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11586:     printf("Problem with %s \n",optionfilehtm);
                   11587:     exit(0);
1.126     brouard  11588:   }
                   11589: 
                   11590:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11591:   strcat(optionfilehtmcov,"-cov.htm");
                   11592:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11593:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11594:   }
                   11595:   else{
                   11596:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11597: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11598: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11599:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11600:   }
                   11601: 
1.213     brouard  11602:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11603: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11604: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11605: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11606: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11607: \n\
                   11608: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11609:  <ul><li><h4>Parameter files</h4>\n\
                   11610:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11611:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11612:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11613:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11614:  - Date and time at start: %s</ul>\n",\
                   11615:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11616:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11617:          fileres,fileres,\
                   11618:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11619:   fflush(fichtm);
                   11620: 
                   11621:   strcpy(pathr,path);
                   11622:   strcat(pathr,optionfilefiname);
1.184     brouard  11623: #ifdef WIN32
                   11624:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11625: #else
1.126     brouard  11626:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11627: #endif
                   11628:          
1.126     brouard  11629:   
1.220     brouard  11630:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11631:                 and for any valid combination of covariates
1.126     brouard  11632:      and prints on file fileres'p'. */
1.251     brouard  11633:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11634:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11635: 
                   11636:   fprintf(fichtm,"\n");
1.274     brouard  11637:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%f \n<li>Interval for the elementary matrix (in month): stepm=%d",\
                   11638:          ftol, stepm);
                   11639:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11640:   ncurrv=1;
                   11641:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11642:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11643:   ncurrv=i;
                   11644:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11645:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11646:   ncurrv=i;
                   11647:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11648:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11649:   ncurrv=i;
                   11650:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11651:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11652:           nlstate, ndeath, maxwav, mle, weightopt);
                   11653: 
                   11654:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11655: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11656: 
                   11657:   
                   11658:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11659: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11660: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11661:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11662:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11663:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11664:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11665:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11666:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11667: 
1.126     brouard  11668:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11669:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11670:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11671: 
                   11672:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11673:   /* For mortality only */
1.126     brouard  11674:   if (mle==-3){
1.136     brouard  11675:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11676:     for(i=1;i<=NDIM;i++)
                   11677:       for(j=1;j<=NDIM;j++)
                   11678:        ximort[i][j]=0.;
1.186     brouard  11679:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11680:     cens=ivector(1,n);
                   11681:     ageexmed=vector(1,n);
                   11682:     agecens=vector(1,n);
                   11683:     dcwave=ivector(1,n);
1.223     brouard  11684:                
1.126     brouard  11685:     for (i=1; i<=imx; i++){
                   11686:       dcwave[i]=-1;
                   11687:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11688:        if (s[m][i]>nlstate) {
                   11689:          dcwave[i]=m;
                   11690:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11691:          break;
                   11692:        }
1.126     brouard  11693:     }
1.226     brouard  11694:     
1.126     brouard  11695:     for (i=1; i<=imx; i++) {
                   11696:       if (wav[i]>0){
1.226     brouard  11697:        ageexmed[i]=agev[mw[1][i]][i];
                   11698:        j=wav[i];
                   11699:        agecens[i]=1.; 
                   11700:        
                   11701:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11702:          agecens[i]=agev[mw[j][i]][i];
                   11703:          cens[i]= 1;
                   11704:        }else if (ageexmed[i]< 1) 
                   11705:          cens[i]= -1;
                   11706:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11707:          cens[i]=0 ;
1.126     brouard  11708:       }
                   11709:       else cens[i]=-1;
                   11710:     }
                   11711:     
                   11712:     for (i=1;i<=NDIM;i++) {
                   11713:       for (j=1;j<=NDIM;j++)
1.226     brouard  11714:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11715:     }
                   11716:     
1.145     brouard  11717:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11718:     /*printf("%lf %lf", p[1], p[2]);*/
                   11719:     
                   11720:     
1.136     brouard  11721: #ifdef GSL
                   11722:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11723: #else
1.126     brouard  11724:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11725: #endif
1.201     brouard  11726:     strcpy(filerespow,"POW-MORT_"); 
                   11727:     strcat(filerespow,fileresu);
1.126     brouard  11728:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11729:       printf("Problem with resultfile: %s\n", filerespow);
                   11730:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11731:     }
1.136     brouard  11732: #ifdef GSL
                   11733:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11734: #else
1.126     brouard  11735:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11736: #endif
1.126     brouard  11737:     /*  for (i=1;i<=nlstate;i++)
                   11738:        for(j=1;j<=nlstate+ndeath;j++)
                   11739:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11740:     */
                   11741:     fprintf(ficrespow,"\n");
1.136     brouard  11742: #ifdef GSL
                   11743:     /* gsl starts here */ 
                   11744:     T = gsl_multimin_fminimizer_nmsimplex;
                   11745:     gsl_multimin_fminimizer *sfm = NULL;
                   11746:     gsl_vector *ss, *x;
                   11747:     gsl_multimin_function minex_func;
                   11748: 
                   11749:     /* Initial vertex size vector */
                   11750:     ss = gsl_vector_alloc (NDIM);
                   11751:     
                   11752:     if (ss == NULL){
                   11753:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11754:     }
                   11755:     /* Set all step sizes to 1 */
                   11756:     gsl_vector_set_all (ss, 0.001);
                   11757: 
                   11758:     /* Starting point */
1.126     brouard  11759:     
1.136     brouard  11760:     x = gsl_vector_alloc (NDIM);
                   11761:     
                   11762:     if (x == NULL){
                   11763:       gsl_vector_free(ss);
                   11764:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11765:     }
                   11766:   
                   11767:     /* Initialize method and iterate */
                   11768:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11769:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11770:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11771:     gsl_vector_set(x, 0, p[1]);
                   11772:     gsl_vector_set(x, 1, p[2]);
                   11773: 
                   11774:     minex_func.f = &gompertz_f;
                   11775:     minex_func.n = NDIM;
                   11776:     minex_func.params = (void *)&p; /* ??? */
                   11777:     
                   11778:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11779:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11780:     
                   11781:     printf("Iterations beginning .....\n\n");
                   11782:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11783: 
                   11784:     iteri=0;
                   11785:     while (rval == GSL_CONTINUE){
                   11786:       iteri++;
                   11787:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11788:       
                   11789:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11790:       fflush(0);
                   11791:       
                   11792:       if (status) 
                   11793:         break;
                   11794:       
                   11795:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11796:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11797:       
                   11798:       if (rval == GSL_SUCCESS)
                   11799:         printf ("converged to a local maximum at\n");
                   11800:       
                   11801:       printf("%5d ", iteri);
                   11802:       for (it = 0; it < NDIM; it++){
                   11803:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11804:       }
                   11805:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11806:     }
                   11807:     
                   11808:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11809:     
                   11810:     gsl_vector_free(x); /* initial values */
                   11811:     gsl_vector_free(ss); /* inital step size */
                   11812:     for (it=0; it<NDIM; it++){
                   11813:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11814:       fprintf(ficrespow," %.12lf", p[it]);
                   11815:     }
                   11816:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11817: #endif
                   11818: #ifdef POWELL
                   11819:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11820: #endif  
1.126     brouard  11821:     fclose(ficrespow);
                   11822:     
1.203     brouard  11823:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11824: 
                   11825:     for(i=1; i <=NDIM; i++)
                   11826:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11827:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11828:     
                   11829:     printf("\nCovariance matrix\n ");
1.203     brouard  11830:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11831:     for(i=1; i <=NDIM; i++) {
                   11832:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11833:                                printf("%f ",matcov[i][j]);
                   11834:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11835:       }
1.203     brouard  11836:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11837:     }
                   11838:     
                   11839:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11840:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11841:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11842:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11843:     }
1.126     brouard  11844:     lsurv=vector(1,AGESUP);
                   11845:     lpop=vector(1,AGESUP);
                   11846:     tpop=vector(1,AGESUP);
                   11847:     lsurv[agegomp]=100000;
                   11848:     
                   11849:     for (k=agegomp;k<=AGESUP;k++) {
                   11850:       agemortsup=k;
                   11851:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11852:     }
                   11853:     
                   11854:     for (k=agegomp;k<agemortsup;k++)
                   11855:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11856:     
                   11857:     for (k=agegomp;k<agemortsup;k++){
                   11858:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11859:       sumlpop=sumlpop+lpop[k];
                   11860:     }
                   11861:     
                   11862:     tpop[agegomp]=sumlpop;
                   11863:     for (k=agegomp;k<(agemortsup-3);k++){
                   11864:       /*  tpop[k+1]=2;*/
                   11865:       tpop[k+1]=tpop[k]-lpop[k];
                   11866:     }
                   11867:     
                   11868:     
                   11869:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11870:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11871:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11872:     
                   11873:     
                   11874:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11875:                ageminpar=50;
                   11876:                agemaxpar=100;
1.194     brouard  11877:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11878:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11879: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11880: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11881:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11882: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11883: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11884:     }else{
                   11885:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11886:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11887:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11888:                }
1.201     brouard  11889:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11890:                     stepm, weightopt,\
                   11891:                     model,imx,p,matcov,agemortsup);
                   11892:     
                   11893:     free_vector(lsurv,1,AGESUP);
                   11894:     free_vector(lpop,1,AGESUP);
                   11895:     free_vector(tpop,1,AGESUP);
1.220     brouard  11896:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11897:     free_ivector(cens,1,n);
                   11898:     free_vector(agecens,1,n);
                   11899:     free_ivector(dcwave,1,n);
1.220     brouard  11900: #ifdef GSL
1.136     brouard  11901: #endif
1.186     brouard  11902:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11903:   /* Standard  */
                   11904:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11905:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11906:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11907:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11908:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11909:     for (k=1; k<=npar;k++)
                   11910:       printf(" %d %8.5f",k,p[k]);
                   11911:     printf("\n");
1.205     brouard  11912:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11913:       /* mlikeli uses func not funcone */
1.247     brouard  11914:       /* for(i=1;i<nlstate;i++){ */
                   11915:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11916:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11917:       /* } */
1.205     brouard  11918:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11919:     }
                   11920:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11921:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11922:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11923:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11924:     }
                   11925:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11926:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11927:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11928:     for (k=1; k<=npar;k++)
                   11929:       printf(" %d %8.5f",k,p[k]);
                   11930:     printf("\n");
                   11931:     
                   11932:     /*--------- results files --------------*/
1.283     brouard  11933:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11934:     
                   11935:     
                   11936:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11937:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11938:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11939:     for(i=1,jk=1; i <=nlstate; i++){
                   11940:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11941:        if (k != i) {
                   11942:          printf("%d%d ",i,k);
                   11943:          fprintf(ficlog,"%d%d ",i,k);
                   11944:          fprintf(ficres,"%1d%1d ",i,k);
                   11945:          for(j=1; j <=ncovmodel; j++){
                   11946:            printf("%12.7f ",p[jk]);
                   11947:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11948:            fprintf(ficres,"%12.7f ",p[jk]);
                   11949:            jk++; 
                   11950:          }
                   11951:          printf("\n");
                   11952:          fprintf(ficlog,"\n");
                   11953:          fprintf(ficres,"\n");
                   11954:        }
1.126     brouard  11955:       }
                   11956:     }
1.203     brouard  11957:     if(mle != 0){
                   11958:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11959:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11960:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11961:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11962:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11963:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11964:        for(k=1; k <=(nlstate+ndeath); k++){
                   11965:          if (k != i) {
                   11966:            printf("%d%d ",i,k);
                   11967:            fprintf(ficlog,"%d%d ",i,k);
                   11968:            for(j=1; j <=ncovmodel; j++){
                   11969:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11970:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11971:              jk++; 
                   11972:            }
                   11973:            printf("\n");
                   11974:            fprintf(ficlog,"\n");
                   11975:          }
                   11976:        }
1.193     brouard  11977:       }
1.203     brouard  11978:     } /* end of hesscov and Wald tests */
1.225     brouard  11979:     
1.203     brouard  11980:     /*  */
1.126     brouard  11981:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11982:     printf("# Scales (for hessian or gradient estimation)\n");
                   11983:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11984:     for(i=1,jk=1; i <=nlstate; i++){
                   11985:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11986:        if (j!=i) {
                   11987:          fprintf(ficres,"%1d%1d",i,j);
                   11988:          printf("%1d%1d",i,j);
                   11989:          fprintf(ficlog,"%1d%1d",i,j);
                   11990:          for(k=1; k<=ncovmodel;k++){
                   11991:            printf(" %.5e",delti[jk]);
                   11992:            fprintf(ficlog," %.5e",delti[jk]);
                   11993:            fprintf(ficres," %.5e",delti[jk]);
                   11994:            jk++;
                   11995:          }
                   11996:          printf("\n");
                   11997:          fprintf(ficlog,"\n");
                   11998:          fprintf(ficres,"\n");
                   11999:        }
1.126     brouard  12000:       }
                   12001:     }
                   12002:     
                   12003:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12004:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12005:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12006:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12007:     /* # 121 Var(a12)\n\ */
                   12008:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12009:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12010:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12011:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12012:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12013:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12014:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12015:     
                   12016:     
                   12017:     /* Just to have a covariance matrix which will be more understandable
                   12018:        even is we still don't want to manage dictionary of variables
                   12019:     */
                   12020:     for(itimes=1;itimes<=2;itimes++){
                   12021:       jj=0;
                   12022:       for(i=1; i <=nlstate; i++){
1.225     brouard  12023:        for(j=1; j <=nlstate+ndeath; j++){
                   12024:          if(j==i) continue;
                   12025:          for(k=1; k<=ncovmodel;k++){
                   12026:            jj++;
                   12027:            ca[0]= k+'a'-1;ca[1]='\0';
                   12028:            if(itimes==1){
                   12029:              if(mle>=1)
                   12030:                printf("#%1d%1d%d",i,j,k);
                   12031:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12032:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12033:            }else{
                   12034:              if(mle>=1)
                   12035:                printf("%1d%1d%d",i,j,k);
                   12036:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12037:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12038:            }
                   12039:            ll=0;
                   12040:            for(li=1;li <=nlstate; li++){
                   12041:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12042:                if(lj==li) continue;
                   12043:                for(lk=1;lk<=ncovmodel;lk++){
                   12044:                  ll++;
                   12045:                  if(ll<=jj){
                   12046:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12047:                    if(ll<jj){
                   12048:                      if(itimes==1){
                   12049:                        if(mle>=1)
                   12050:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12051:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12052:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12053:                      }else{
                   12054:                        if(mle>=1)
                   12055:                          printf(" %.5e",matcov[jj][ll]); 
                   12056:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12057:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12058:                      }
                   12059:                    }else{
                   12060:                      if(itimes==1){
                   12061:                        if(mle>=1)
                   12062:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12063:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12064:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12065:                      }else{
                   12066:                        if(mle>=1)
                   12067:                          printf(" %.7e",matcov[jj][ll]); 
                   12068:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12069:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12070:                      }
                   12071:                    }
                   12072:                  }
                   12073:                } /* end lk */
                   12074:              } /* end lj */
                   12075:            } /* end li */
                   12076:            if(mle>=1)
                   12077:              printf("\n");
                   12078:            fprintf(ficlog,"\n");
                   12079:            fprintf(ficres,"\n");
                   12080:            numlinepar++;
                   12081:          } /* end k*/
                   12082:        } /*end j */
1.126     brouard  12083:       } /* end i */
                   12084:     } /* end itimes */
                   12085:     
                   12086:     fflush(ficlog);
                   12087:     fflush(ficres);
1.225     brouard  12088:     while(fgets(line, MAXLINE, ficpar)) {
                   12089:       /* If line starts with a # it is a comment */
                   12090:       if (line[0] == '#') {
                   12091:        numlinepar++;
                   12092:        fputs(line,stdout);
                   12093:        fputs(line,ficparo);
                   12094:        fputs(line,ficlog);
                   12095:        continue;
                   12096:       }else
                   12097:        break;
                   12098:     }
                   12099:     
1.209     brouard  12100:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12101:     /*   ungetc(c,ficpar); */
                   12102:     /*   fgets(line, MAXLINE, ficpar); */
                   12103:     /*   fputs(line,stdout); */
                   12104:     /*   fputs(line,ficparo); */
                   12105:     /* } */
                   12106:     /* ungetc(c,ficpar); */
1.126     brouard  12107:     
                   12108:     estepm=0;
1.209     brouard  12109:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12110:       
                   12111:       if (num_filled != 6) {
                   12112:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12113:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12114:        goto end;
                   12115:       }
                   12116:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12117:     }
                   12118:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12119:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12120:     
1.209     brouard  12121:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12122:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12123:     if (fage <= 2) {
                   12124:       bage = ageminpar;
                   12125:       fage = agemaxpar;
                   12126:     }
                   12127:     
                   12128:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12129:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12130:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12131:                
1.186     brouard  12132:     /* Other stuffs, more or less useful */    
1.254     brouard  12133:     while(fgets(line, MAXLINE, ficpar)) {
                   12134:       /* If line starts with a # it is a comment */
                   12135:       if (line[0] == '#') {
                   12136:        numlinepar++;
                   12137:        fputs(line,stdout);
                   12138:        fputs(line,ficparo);
                   12139:        fputs(line,ficlog);
                   12140:        continue;
                   12141:       }else
                   12142:        break;
                   12143:     }
                   12144: 
                   12145:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12146:       
                   12147:       if (num_filled != 7) {
                   12148:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12149:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12150:        goto end;
                   12151:       }
                   12152:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12153:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12154:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12155:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12156:     }
1.254     brouard  12157: 
                   12158:     while(fgets(line, MAXLINE, ficpar)) {
                   12159:       /* If line starts with a # it is a comment */
                   12160:       if (line[0] == '#') {
                   12161:        numlinepar++;
                   12162:        fputs(line,stdout);
                   12163:        fputs(line,ficparo);
                   12164:        fputs(line,ficlog);
                   12165:        continue;
                   12166:       }else
                   12167:        break;
1.126     brouard  12168:     }
                   12169:     
                   12170:     
                   12171:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12172:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12173:     
1.254     brouard  12174:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12175:       if (num_filled != 1) {
                   12176:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12177:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12178:        goto end;
                   12179:       }
                   12180:       printf("pop_based=%d\n",popbased);
                   12181:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12182:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12183:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12184:     }
                   12185:      
1.258     brouard  12186:     /* Results */
                   12187:     nresult=0;
                   12188:     do{
                   12189:       if(!fgets(line, MAXLINE, ficpar)){
                   12190:        endishere=1;
                   12191:        parameterline=14;
                   12192:       }else if (line[0] == '#') {
                   12193:        /* If line starts with a # it is a comment */
1.254     brouard  12194:        numlinepar++;
                   12195:        fputs(line,stdout);
                   12196:        fputs(line,ficparo);
                   12197:        fputs(line,ficlog);
                   12198:        continue;
1.258     brouard  12199:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12200:        parameterline=11;
                   12201:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12202:        parameterline=12;
                   12203:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12204:        parameterline=13;
                   12205:       else{
                   12206:        parameterline=14;
1.254     brouard  12207:       }
1.258     brouard  12208:       switch (parameterline){ 
                   12209:       case 11:
                   12210:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12211:          if (num_filled != 8) {
                   12212:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12213:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12214:            goto end;
                   12215:          }
                   12216:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12217:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12218:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12219:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12220:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12221:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12222:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12223: 
1.258     brouard  12224:        }
1.254     brouard  12225:        break;
1.258     brouard  12226:       case 12:
                   12227:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12228:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12229:          if (num_filled != 8) {
1.262     brouard  12230:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12231:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12232:            goto end;
                   12233:          }
                   12234:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12235:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12236:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12237:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12238:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12239:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12240:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12241:        }
1.230     brouard  12242:        break;
1.258     brouard  12243:       case 13:
                   12244:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12245:          if (num_filled == 0){
                   12246:            resultline[0]='\0';
                   12247:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12248:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12249:            break;
                   12250:          } else if (num_filled != 1){
                   12251:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12252:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12253:          }
                   12254:          nresult++; /* Sum of resultlines */
                   12255:          printf("Result %d: result=%s\n",nresult, resultline);
                   12256:          if(nresult > MAXRESULTLINES){
                   12257:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12258:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12259:            goto end;
                   12260:          }
                   12261:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12262:          fprintf(ficparo,"result: %s\n",resultline);
                   12263:          fprintf(ficres,"result: %s\n",resultline);
                   12264:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12265:          break;
1.258     brouard  12266:        case 14: 
1.259     brouard  12267:          if(ncovmodel >2 && nresult==0 ){
                   12268:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12269:            goto end;
                   12270:          }
1.259     brouard  12271:          break;
1.258     brouard  12272:        default:
                   12273:          nresult=1;
                   12274:          decoderesult(".",nresult ); /* No covariate */
                   12275:        }
                   12276:       } /* End switch parameterline */
                   12277:     }while(endishere==0); /* End do */
1.126     brouard  12278:     
1.230     brouard  12279:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12280:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12281:     
                   12282:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12283:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12284:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12285: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12286: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12287:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12288: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12289: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12290:     }else{
1.270     brouard  12291:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12292:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12293:     }
                   12294:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12295:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12296:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12297:                
1.225     brouard  12298:     /*------------ free_vector  -------------*/
                   12299:     /*  chdir(path); */
1.220     brouard  12300:                
1.215     brouard  12301:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12302:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12303:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12304:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12305:     free_lvector(num,1,n);
                   12306:     free_vector(agedc,1,n);
                   12307:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12308:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12309:     fclose(ficparo);
                   12310:     fclose(ficres);
1.220     brouard  12311:                
                   12312:                
1.186     brouard  12313:     /* Other results (useful)*/
1.220     brouard  12314:                
                   12315:                
1.126     brouard  12316:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12317:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12318:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12319:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12320:     fclose(ficrespl);
                   12321: 
                   12322:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12323:     /*#include "hpijx.h"*/
                   12324:     hPijx(p, bage, fage);
1.145     brouard  12325:     fclose(ficrespij);
1.227     brouard  12326:     
1.220     brouard  12327:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12328:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12329:     k=1;
1.126     brouard  12330:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12331:     
1.269     brouard  12332:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12333:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12334:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12335:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12336:        for(k=1;k<=ncovcombmax;k++)
                   12337:          probs[i][j][k]=0.;
1.269     brouard  12338:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12339:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12340:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12341:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12342:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12343:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12344:          for(k=1;k<=ncovcombmax;k++)
                   12345:            mobaverages[i][j][k]=0.;
1.219     brouard  12346:       mobaverage=mobaverages;
                   12347:       if (mobilav!=0) {
1.235     brouard  12348:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12349:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12350:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12351:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12352:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12353:        }
1.269     brouard  12354:       } else if (mobilavproj !=0) {
1.235     brouard  12355:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12356:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12357:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12358:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12359:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12360:        }
1.269     brouard  12361:       }else{
                   12362:        printf("Internal error moving average\n");
                   12363:        fflush(stdout);
                   12364:        exit(1);
1.219     brouard  12365:       }
                   12366:     }/* end if moving average */
1.227     brouard  12367:     
1.126     brouard  12368:     /*---------- Forecasting ------------------*/
                   12369:     if(prevfcast==1){
                   12370:       /*    if(stepm ==1){*/
1.269     brouard  12371:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12372:     }
1.269     brouard  12373: 
                   12374:     /* Backcasting */
1.217     brouard  12375:     if(backcast==1){
1.219     brouard  12376:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12377:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12378:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12379: 
                   12380:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12381: 
                   12382:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12383: 
1.219     brouard  12384:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12385:       fclose(ficresplb);
                   12386: 
1.222     brouard  12387:       hBijx(p, bage, fage, mobaverage);
                   12388:       fclose(ficrespijb);
1.219     brouard  12389: 
1.269     brouard  12390:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12391:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12392:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12393: 
                   12394:       
1.269     brouard  12395:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12396:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12397:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12398:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12399:     }    /* end  Backcasting */
1.268     brouard  12400:  
1.186     brouard  12401:  
                   12402:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12403: 
1.215     brouard  12404:     free_ivector(wav,1,imx);
                   12405:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12406:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12407:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12408:                
                   12409:                
1.127     brouard  12410:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12411:                
1.201     brouard  12412:     strcpy(filerese,"E_");
                   12413:     strcat(filerese,fileresu);
1.126     brouard  12414:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12415:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12416:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12417:     }
1.208     brouard  12418:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12419:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12420: 
                   12421:     pstamp(ficreseij);
1.219     brouard  12422:                
1.235     brouard  12423:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12424:     if (cptcovn < 1){i1=1;}
                   12425:     
                   12426:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12427:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12428:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12429:        continue;
1.219     brouard  12430:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12431:       printf("\n#****** ");
1.225     brouard  12432:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12433:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12434:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12435:       }
                   12436:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12437:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12438:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12439:       }
                   12440:       fprintf(ficreseij,"******\n");
1.235     brouard  12441:       printf("******\n");
1.219     brouard  12442:       
                   12443:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12444:       oldm=oldms;savm=savms;
1.235     brouard  12445:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12446:       
1.219     brouard  12447:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12448:     }
                   12449:     fclose(ficreseij);
1.208     brouard  12450:     printf("done evsij\n");fflush(stdout);
                   12451:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12452: 
1.218     brouard  12453:                
1.227     brouard  12454:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12455:                
1.201     brouard  12456:     strcpy(filerest,"T_");
                   12457:     strcat(filerest,fileresu);
1.127     brouard  12458:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12459:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12460:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12461:     }
1.208     brouard  12462:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12463:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12464:     strcpy(fileresstde,"STDE_");
                   12465:     strcat(fileresstde,fileresu);
1.126     brouard  12466:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12467:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12468:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12469:     }
1.227     brouard  12470:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12471:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12472: 
1.201     brouard  12473:     strcpy(filerescve,"CVE_");
                   12474:     strcat(filerescve,fileresu);
1.126     brouard  12475:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12476:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12477:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12478:     }
1.227     brouard  12479:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12480:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12481: 
1.201     brouard  12482:     strcpy(fileresv,"V_");
                   12483:     strcat(fileresv,fileresu);
1.126     brouard  12484:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12485:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12486:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12487:     }
1.227     brouard  12488:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12489:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12490: 
1.235     brouard  12491:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12492:     if (cptcovn < 1){i1=1;}
                   12493:     
                   12494:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12495:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12496:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12497:        continue;
1.242     brouard  12498:       printf("\n#****** Result for:");
                   12499:       fprintf(ficrest,"\n#****** Result for:");
                   12500:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12501:       for(j=1;j<=cptcoveff;j++){ 
                   12502:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12503:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12504:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12505:       }
1.235     brouard  12506:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12507:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12508:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12509:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12510:       }        
1.208     brouard  12511:       fprintf(ficrest,"******\n");
1.227     brouard  12512:       fprintf(ficlog,"******\n");
                   12513:       printf("******\n");
1.208     brouard  12514:       
                   12515:       fprintf(ficresstdeij,"\n#****** ");
                   12516:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12517:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12518:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12519:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12520:       }
1.235     brouard  12521:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12522:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12523:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12524:       }        
1.208     brouard  12525:       fprintf(ficresstdeij,"******\n");
                   12526:       fprintf(ficrescveij,"******\n");
                   12527:       
                   12528:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12529:       /* pstamp(ficresvij); */
1.225     brouard  12530:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12531:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12532:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12533:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12534:       }        
1.208     brouard  12535:       fprintf(ficresvij,"******\n");
                   12536:       
                   12537:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12538:       oldm=oldms;savm=savms;
1.235     brouard  12539:       printf(" cvevsij ");
                   12540:       fprintf(ficlog, " cvevsij ");
                   12541:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12542:       printf(" end cvevsij \n ");
                   12543:       fprintf(ficlog, " end cvevsij \n ");
                   12544:       
                   12545:       /*
                   12546:        */
                   12547:       /* goto endfree; */
                   12548:       
                   12549:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12550:       pstamp(ficrest);
                   12551:       
1.269     brouard  12552:       epj=vector(1,nlstate+1);
1.208     brouard  12553:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12554:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12555:        cptcod= 0; /* To be deleted */
                   12556:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12557:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12558:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12559:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12560:        if(vpopbased==1)
                   12561:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12562:        else
                   12563:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12564:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12565:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12566:        fprintf(ficrest,"\n");
                   12567:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12568:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12569:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12570:        for(age=bage; age <=fage ;age++){
1.235     brouard  12571:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12572:          if (vpopbased==1) {
                   12573:            if(mobilav ==0){
                   12574:              for(i=1; i<=nlstate;i++)
                   12575:                prlim[i][i]=probs[(int)age][i][k];
                   12576:            }else{ /* mobilav */ 
                   12577:              for(i=1; i<=nlstate;i++)
                   12578:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12579:            }
                   12580:          }
1.219     brouard  12581:          
1.227     brouard  12582:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12583:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12584:          /* printf(" age %4.0f ",age); */
                   12585:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12586:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12587:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12588:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12589:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12590:            }
                   12591:            epj[nlstate+1] +=epj[j];
                   12592:          }
                   12593:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12594:          
1.227     brouard  12595:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12596:            for(j=1;j <=nlstate;j++)
                   12597:              vepp += vareij[i][j][(int)age];
                   12598:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12599:          for(j=1;j <=nlstate;j++){
                   12600:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12601:          }
                   12602:          fprintf(ficrest,"\n");
                   12603:        }
1.208     brouard  12604:       } /* End vpopbased */
1.269     brouard  12605:       free_vector(epj,1,nlstate+1);
1.208     brouard  12606:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12607:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12608:       printf("done selection\n");fflush(stdout);
                   12609:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12610:       
1.235     brouard  12611:     } /* End k selection */
1.227     brouard  12612: 
                   12613:     printf("done State-specific expectancies\n");fflush(stdout);
                   12614:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12615: 
1.269     brouard  12616:     /* variance-covariance of period prevalence*/
                   12617:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12618: 
1.227     brouard  12619:     
                   12620:     free_vector(weight,1,n);
                   12621:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12622:     free_imatrix(s,1,maxwav+1,1,n);
                   12623:     free_matrix(anint,1,maxwav,1,n); 
                   12624:     free_matrix(mint,1,maxwav,1,n);
                   12625:     free_ivector(cod,1,n);
                   12626:     free_ivector(tab,1,NCOVMAX);
                   12627:     fclose(ficresstdeij);
                   12628:     fclose(ficrescveij);
                   12629:     fclose(ficresvij);
                   12630:     fclose(ficrest);
                   12631:     fclose(ficpar);
                   12632:     
                   12633:     
1.126     brouard  12634:     /*---------- End : free ----------------*/
1.219     brouard  12635:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12636:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12637:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12638:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12639:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12640:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12641:   /* endfree:*/
                   12642:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12643:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12644:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12645:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12646:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12647:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12648:   free_matrix(covar,0,NCOVMAX,1,n);
                   12649:   free_matrix(matcov,1,npar,1,npar);
                   12650:   free_matrix(hess,1,npar,1,npar);
                   12651:   /*free_vector(delti,1,npar);*/
                   12652:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12653:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12654:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12655:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12656:   
                   12657:   free_ivector(ncodemax,1,NCOVMAX);
                   12658:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12659:   free_ivector(Dummy,-1,NCOVMAX);
                   12660:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12661:   free_ivector(DummyV,1,NCOVMAX);
                   12662:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12663:   free_ivector(Typevar,-1,NCOVMAX);
                   12664:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12665:   free_ivector(TvarsQ,1,NCOVMAX);
                   12666:   free_ivector(TvarsQind,1,NCOVMAX);
                   12667:   free_ivector(TvarsD,1,NCOVMAX);
                   12668:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12669:   free_ivector(TvarFD,1,NCOVMAX);
                   12670:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12671:   free_ivector(TvarF,1,NCOVMAX);
                   12672:   free_ivector(TvarFind,1,NCOVMAX);
                   12673:   free_ivector(TvarV,1,NCOVMAX);
                   12674:   free_ivector(TvarVind,1,NCOVMAX);
                   12675:   free_ivector(TvarA,1,NCOVMAX);
                   12676:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12677:   free_ivector(TvarFQ,1,NCOVMAX);
                   12678:   free_ivector(TvarFQind,1,NCOVMAX);
                   12679:   free_ivector(TvarVD,1,NCOVMAX);
                   12680:   free_ivector(TvarVDind,1,NCOVMAX);
                   12681:   free_ivector(TvarVQ,1,NCOVMAX);
                   12682:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12683:   free_ivector(Tvarsel,1,NCOVMAX);
                   12684:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12685:   free_ivector(Tposprod,1,NCOVMAX);
                   12686:   free_ivector(Tprod,1,NCOVMAX);
                   12687:   free_ivector(Tvaraff,1,NCOVMAX);
                   12688:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12689:   free_ivector(Tage,1,NCOVMAX);
                   12690:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12691:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12692:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12693:   
                   12694:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12695:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12696:   fflush(fichtm);
                   12697:   fflush(ficgp);
                   12698:   
1.227     brouard  12699:   
1.126     brouard  12700:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12701:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12702:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12703:   }else{
                   12704:     printf("End of Imach\n");
                   12705:     fprintf(ficlog,"End of Imach\n");
                   12706:   }
                   12707:   printf("See log file on %s\n",filelog);
                   12708:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12709:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12710:   rend_time = time(NULL);  
                   12711:   end_time = *localtime(&rend_time);
                   12712:   /* tml = *localtime(&end_time.tm_sec); */
                   12713:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12714:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12715:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12716:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12717:   
1.157     brouard  12718:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12719:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12720:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12721:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12722: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12723:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12724:   fclose(fichtm);
                   12725:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12726:   fclose(fichtmcov);
                   12727:   fclose(ficgp);
                   12728:   fclose(ficlog);
                   12729:   /*------ End -----------*/
1.227     brouard  12730:   
1.281     brouard  12731: 
                   12732: /* Executes gnuplot */
1.227     brouard  12733:   
                   12734:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12735: #ifdef WIN32
1.227     brouard  12736:   if (_chdir(pathcd) != 0)
                   12737:     printf("Can't move to directory %s!\n",path);
                   12738:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12739: #else
1.227     brouard  12740:     if(chdir(pathcd) != 0)
                   12741:       printf("Can't move to directory %s!\n", path);
                   12742:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12743: #endif 
1.126     brouard  12744:     printf("Current directory %s!\n",pathcd);
                   12745:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12746:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12747: #ifdef _WIN32
1.126     brouard  12748:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12749: #endif
                   12750:   if(!stat(plotcmd,&info)){
1.158     brouard  12751:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12752:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12753:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12754:     }else
                   12755:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12756: #ifdef __unix
1.126     brouard  12757:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12758:     if(!stat(plotcmd,&info)){
1.158     brouard  12759:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12760:     }else
                   12761:       strcpy(pplotcmd,plotcmd);
                   12762: #endif
                   12763:   }else
                   12764:     strcpy(pplotcmd,plotcmd);
                   12765:   
                   12766:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12767:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12768:   
1.126     brouard  12769:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12770:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12771:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12772:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12773:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12774:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12775:   }
1.158     brouard  12776:   printf(" Successful, please wait...");
1.126     brouard  12777:   while (z[0] != 'q') {
                   12778:     /* chdir(path); */
1.154     brouard  12779:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12780:     scanf("%s",z);
                   12781: /*     if (z[0] == 'c') system("./imach"); */
                   12782:     if (z[0] == 'e') {
1.158     brouard  12783: #ifdef __APPLE__
1.152     brouard  12784:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12785: #elif __linux
                   12786:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12787: #else
1.152     brouard  12788:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12789: #endif
                   12790:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12791:       system(pplotcmd);
1.126     brouard  12792:     }
                   12793:     else if (z[0] == 'g') system(plotcmd);
                   12794:     else if (z[0] == 'q') exit(0);
                   12795:   }
1.227     brouard  12796: end:
1.126     brouard  12797:   while (z[0] != 'q') {
1.195     brouard  12798:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12799:     scanf("%s",z);
                   12800:   }
1.283     brouard  12801:   printf("End\n");
1.282     brouard  12802:   exit(0);
1.126     brouard  12803: }

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